Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Head and Neck Neoplasms
go back to main search page
Accession:DOID:9006169 term browser browse the term
Definition:Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)
Synonyms:exact_synonym: Head Neoplasms;   Head, Neck Neoplasms;   Neck Neoplasms;   UADT Neoplasm;   UADT Neoplasms;   Upper Aerodigestive Tract Neoplasms;   upper aerodigestive tract neoplasm
 narrow_synonym: Cancer of Head;   Cancer of Neck;   Cancer of the Head;   Cancer of the Neck;   Head Cancer;   Neck Cancer
 primary_id: MESH:D006258
 alt_id: RDO:0000780
 xref: EFO:0004284;   EFO:0005950



show annotations for term's descendants           Sort by:
Head and Neck Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOBEC3B apolipoprotein B mRNA editing enzyme catalytic subunit 3B EXP CTD Direct Evidence: marker/mechanism CTD PMID:23852168 NCBI chr22:38,982,347...38,992,779
Ensembl chr22:38,982,347...38,992,804
JBrowse link
G AREG amphiregulin EXP CTD Direct Evidence: marker/mechanism CTD PMID:15342401 NCBI chr 4:74,445,136...74,455,005
Ensembl chr 4:74,445,136...74,455,005
JBrowse link
G BAP1 BRCA1 associated protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25231345 NCBI chr 3:52,401,008...52,410,008
Ensembl chr 3:52,401,008...52,410,008
JBrowse link
G BCL2 BCL2 apoptosis regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:18566236 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L1 BCL2 like 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18566236 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G CEBPA CCAAT enhancer binding protein alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:17510391 NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534
JBrowse link
G CSF3 colony stimulating factor 3 EXP CTD Direct Evidence: therapeutic CTD PMID:7692001 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813
JBrowse link
G DPYD dihydropyrimidine dehydrogenase EXP CTD Direct Evidence: marker/mechanism CTD PMID:19020767 NCBI chr 1:97,077,743...97,921,059
Ensembl chr 1:97,077,743...97,995,000
JBrowse link
G EGFR epidermal growth factor receptor IMP
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:12942316 PMID:15342401 PMID:23917044 PMID:16467544 RGD:5131641 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit severity IEP mRNA:increased expression: : RGD PMID:26659720 RGD:11573297 NCBI chr19:45,349,837...45,370,573
Ensembl chr19:45,349,837...45,370,918
JBrowse link
G FAT1 FAT atypical cadherin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23354438 NCBI chr 4:186,587,794...186,726,696
Ensembl chr 4:186,587,794...186,726,722
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 IAGP ClinVar Annotator: match by term: Head and Neck Neoplasms ClinVar PMID:7668257 PMID:7719344 PMID:8651276 PMID:9677057 PMID:9700203 More... NCBI chr10:121,478,330...121,598,458
Ensembl chr10:121,478,332...121,598,458
JBrowse link
G GPX1 glutathione peroxidase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15557674 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
JBrowse link
G GRP gastrin releasing peptide EXP CTD Direct Evidence: marker/mechanism CTD PMID:15342401 NCBI chr18:59,219,189...59,230,771
Ensembl chr18:59,220,158...59,230,774
JBrowse link
G MAL mal, T cell differentiation protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:19445022 NCBI chr 2:95,025,708...95,053,992
Ensembl chr 2:95,025,677...95,053,992
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15342401 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15342401 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MMP1 matrix metallopeptidase 1 IAGP DNA:insertion:promoter:g.-1607insG (human) RGD PMID:19843588 RGD:7207056 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha IAGP ClinVar Annotator: match by term: Head and Neck Neoplasms ClinVar PMID:15016963 PMID:15254419 PMID:15647370 PMID:15805248 PMID:16906227 More... NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093
JBrowse link
G PRAME PRAME nuclear receptor transcriptional regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:16179254 NCBI chr22:22,547,701...22,559,265
Ensembl chr22:22,547,701...22,559,361
JBrowse link
G RAD51 RAD51 recombinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:22613844 NCBI chr15:40,694,733...40,732,340
Ensembl chr15:40,694,774...40,732,340
JBrowse link
G RARB retinoic acid receptor beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:17549354 NCBI chr 3:24,829,321...25,597,932
Ensembl chr 3:24,687,887...25,597,932
JBrowse link
G SRSF2 serine and arginine rich splicing factor 2 IEP mRNA:increased expression:head and neck (human) RGD PMID:21764905 RGD:11039047 NCBI chr17:76,734,115...76,737,411
Ensembl chr17:76,734,115...76,737,333
JBrowse link
G STAT6 signal transducer and activator of transcription 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21765211 NCBI chr12:57,095,408...57,111,362
Ensembl chr12:57,095,408...57,132,139
JBrowse link
G TGFA transforming growth factor alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:15342401 NCBI chr 2:70,447,284...70,553,826
Ensembl chr 2:70,447,284...70,554,193
JBrowse link
G TP53 tumor protein p53 IAGP ClinVar Annotator: match by term: Head and Neck Neoplasms ClinVar PMID:9067756 PMID:11370630 PMID:11782540 PMID:16818505 PMID:17606709 More... NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TYMS thymidylate synthetase EXP CTD Direct Evidence: marker/mechanism CTD PMID:19020767 NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578
JBrowse link
G UROD uroporphyrinogen decarboxylase EXP CTD Direct Evidence: marker/mechanism CTD PMID:21270338 NCBI chr 1:45,012,254...45,015,575
Ensembl chr 1:45,010,950...45,015,575
JBrowse link
G VEGFA vascular endothelial growth factor A EXP CTD Direct Evidence: marker/mechanism CTD PMID:16499871 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
G XRCC3 X-ray repair cross complementing 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22613844 NCBI chr14:103,697,617...103,715,451
Ensembl chr14:103,697,609...103,715,504
JBrowse link
acoustic neuroma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARTN artemin IEP mRNA:increased expression:peripheral nerve: RGD PMID:19937367 RGD:8655552 NCBI chr 1:43,933,801...43,937,240
Ensembl chr 1:43,933,320...43,937,240
JBrowse link
G BDNF brain derived neurotrophic factor IEP mRNA:increased expression:peripheral nerve: RGD PMID:19937367 RGD:8655552 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
JBrowse link
G CAV1 caveolin 1 IEP RGD PMID:20881564 RGD:8661782 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A IEP mRNA,protein:decreased expression:myelinated nerve: RGD PMID:20600642 RGD:8661792 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 IAGP DNA:snp:promoter:c.-1053C>T (human) RGD PMID:12540498 RGD:1358568 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit susceptibility IAGP DNA:missense mutation:cds:p.D312N (rs1799793) (human) RGD PMID:20150366 RGD:5688735 NCBI chr19:45,349,837...45,370,573
Ensembl chr19:45,349,837...45,370,918
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 disease_progression IEP RGD PMID:15354013 RGD:11567268 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834
JBrowse link
G GDNF glial cell derived neurotrophic factor IEP mRNA:increased expression:peripheral nerve: RGD PMID:19937367 RGD:8655552 NCBI chr 5:37,812,677...37,840,041
Ensembl chr 5:37,812,677...37,840,041
JBrowse link
G IGF1 insulin like growth factor 1 susceptibility IEP protein:increased expression:serum: RGD PMID:21788435 RGD:8548833 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744
JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 susceptibility IEP protein:increased expression:serum: RGD PMID:21788435 RGD:8548833 NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874
JBrowse link
G NF2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor IEP protein:decreased expression:myelinated nerve: RGD PMID:20600642 RGD:8661792 NCBI chr22:29,603,556...29,698,600
Ensembl chr22:29,603,556...29,698,598
JBrowse link
G VEGFA vascular endothelial growth factor A IDA RGD PMID:14660915 RGD:8547959 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
adenoid cystic carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 (Colton blood group) EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 7:30,911,853...30,925,516
Ensembl chr 7:30,911,853...30,925,517
JBrowse link
G ARID1A AT-rich interaction domain 1A EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 1:26,696,015...26,782,104
Ensembl chr 1:26,693,236...26,782,104
JBrowse link
G ARID2 AT-rich interaction domain 2 IAGP ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar NCBI chr12:45,729,706...45,908,037
Ensembl chr12:45,729,706...45,908,040
JBrowse link
G ARID4B AT-rich interaction domain 4B EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 1:235,166,902...235,328,179
Ensembl chr 1:235,131,634...235,328,219
JBrowse link
G ARID5B AT-rich interaction domain 5B EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr10:61,901,699...62,096,944
Ensembl chr10:61,901,684...62,096,944
JBrowse link
G ASPM assembly factor for spindle microtubules EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 1:197,084,127...197,146,669
Ensembl chr 1:197,084,121...197,146,694
JBrowse link
G ATM ATM serine/threonine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,823...108,369,102
JBrowse link
G ATR ATR serine/threonine kinase treatment IMP RGD PMID:32001675 RGD:150340693 NCBI chr 3:142,449,235...142,578,733
Ensembl chr 3:142,449,007...142,578,733
JBrowse link
G ATRX ATRX chromatin remodeler EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr  X:77,504,880...77,786,216
Ensembl chr  X:77,504,880...77,786,233
JBrowse link
G BAP1 BRCA1 associated protein 1 IAGP ClinVar Annotator: match by term: Adenoid cystic carcinoma
ClinVar Annotator: match by term: Adenocystic carcinoma
ClinVar PMID:21642991 PMID:24894717 PMID:26166446 PMID:26452128 PMID:28492532 NCBI chr 3:52,401,008...52,410,008
Ensembl chr 3:52,401,008...52,410,008
JBrowse link
G BCL11A BCL11 transcription factor A EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 2:60,450,520...60,553,924
Ensembl chr 2:60,450,520...60,554,467
JBrowse link
G BCOR BCL6 corepressor EXP
IAGP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenoid cystic carcinoma
CTD
ClinVar
PMID:23685749 NCBI chr  X:40,051,246...40,177,329
Ensembl chr  X:40,049,815...40,177,329
JBrowse link
G BCORL1 BCL6 corepressor like 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr  X:129,980,313...130,058,071
Ensembl chr  X:129,981,107...130,058,071
JBrowse link
G BRCA1 BRCA1 DNA repair associated EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr17:43,044,295...43,170,327
Ensembl chr17:43,044,295...43,170,245
JBrowse link
G BRD1 bromodomain containing 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr22:49,773,278...49,827,873
Ensembl chr22:49,773,283...49,827,873
JBrowse link
G CCND1 cyclin D1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CDH1 cadherin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17520682 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537
JBrowse link
G CMTR2 cap methyltransferase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr16:71,281,392...71,289,722
Ensembl chr16:71,281,389...71,289,715
JBrowse link
G CNTN6 contactin 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 3:1,093,024...1,404,217
Ensembl chr 3:1,092,658...1,404,217
JBrowse link
G CREBBP CREB binding protein EXP
IAGP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenocystic carcinoma
CTD
ClinVar
PMID:21390126 PMID:21680795 PMID:21796119 PMID:22832583 PMID:23334668 More... NCBI chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713
JBrowse link
G DAPK1 death associated protein kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 9:87,497,228...87,708,634
Ensembl chr 9:87,497,228...87,708,634
JBrowse link
G DTL denticleless E3 ubiquitin protein ligase homolog EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 1:212,035,748...212,105,013
Ensembl chr 1:212,035,553...212,107,400
JBrowse link
G DTX4 deltex E3 ubiquitin ligase 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr11:59,171,430...59,208,588
Ensembl chr11:59,171,430...59,208,588
JBrowse link
G EFHD1 EF-hand domain family member D1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 2:232,606,057...232,682,776
Ensembl chr 2:232,606,057...232,682,776
JBrowse link
G EN1 engrailed homeobox 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 2:118,842,171...118,847,648
Ensembl chr 2:118,842,171...118,847,648
JBrowse link
G EP300 E1A binding protein p300 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,592...41,180,077
JBrowse link
G ERBIN erbb2 interacting protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 5:65,926,575...66,082,546
Ensembl chr 5:65,883,128...66,082,546
JBrowse link
G ESPL1 extra spindle pole bodies like 1, separase EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr12:53,268,299...53,293,638
Ensembl chr12:53,268,299...53,293,638
JBrowse link
G FANCA FA complementation group A EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr16:89,737,549...89,816,647
Ensembl chr16:89,726,683...89,816,977
JBrowse link
G FAT1 FAT atypical cadherin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 4:186,587,794...186,726,696
Ensembl chr 4:186,587,794...186,726,722
JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 EXP
IAGP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenocystic carcinoma
CTD
ClinVar
PMID:23685749 PMID:26619011 NCBI chr 4:152,320,544...152,536,092
Ensembl chr 4:152,320,544...152,536,092
JBrowse link
G FGF16 fibroblast growth factor 16 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr  X:77,447,389...77,457,278
Ensembl chr  X:77,447,389...77,457,278
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 IAGP ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar PMID:26619011 NCBI chr10:121,478,330...121,598,458
Ensembl chr10:121,478,332...121,598,458
JBrowse link
G FGFR4 fibroblast growth factor receptor 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 5:177,086,915...177,098,144
Ensembl chr 5:177,086,905...177,098,144
JBrowse link
G FOXO3 forkhead box O3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774
JBrowse link
G FOXP2 forkhead box P2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 7:114,086,327...114,693,765
Ensembl chr 7:114,086,327...114,693,772
JBrowse link
G GAS2 growth arrest specific 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr11:22,626,002...22,813,055
Ensembl chr11:22,625,509...22,813,001
JBrowse link
G GAS6 growth arrest specific 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr13:113,820,549...113,864,076
Ensembl chr13:113,820,549...113,864,076
JBrowse link
G GINS2 GINS complex subunit 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr16:85,676,198...85,688,954
Ensembl chr16:85,676,198...85,690,073
JBrowse link
G GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 4:155,666,848...155,737,059
Ensembl chr 4:155,666,726...155,737,059
JBrowse link
G H1-4 H1.4 linker histone, cluster member EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 6:26,156,329...26,157,115
Ensembl chr 6:26,156,329...26,157,115
JBrowse link
G H2AC16 H2A clustered histone 16 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 6:27,865,317...27,865,798
Ensembl chr 6:27,865,317...27,865,798
JBrowse link
G HOMER3 homer scaffold protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr19:18,929,201...18,941,217
Ensembl chr19:18,929,201...18,941,261
JBrowse link
G HRAS HRas proto-oncogene, GTPase EXP
IAGP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenocystic carcinoma
CTD
ClinVar
PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321
JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 IAGP ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20946881 More... NCBI chr 2:208,236,227...208,255,071
Ensembl chr 2:208,236,229...208,266,074
JBrowse link
G IGFBP2 insulin like growth factor binding protein 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 2:216,632,828...216,664,436
Ensembl chr 2:216,632,828...216,664,436
JBrowse link
G IL17RD interleukin 17 receptor D EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 3:57,089,982...57,170,317
Ensembl chr 3:57,089,982...57,170,306
JBrowse link
G INSRR insulin receptor related receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 1:156,840,063...156,859,117
Ensembl chr 1:156,840,063...156,859,117
JBrowse link
G IRX4 iroquois homeobox 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 5:1,877,413...1,887,179
Ensembl chr 5:1,877,413...1,887,236
JBrowse link
G ISYNA1 inositol-3-phosphate synthase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr19:18,434,388...18,438,133
Ensembl chr19:18,434,388...18,438,167
JBrowse link
G ITGB4 integrin subunit beta 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr17:75,721,459...75,757,818
Ensembl chr17:75,721,328...75,757,818
JBrowse link
G JAG1 jagged canonical Notch ligand 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr20:10,637,684...10,673,999
Ensembl chr20:10,637,684...10,673,999
JBrowse link
G JAK3 Janus kinase 3 IAGP ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:14615376 PMID:28492532 PMID:33040328 NCBI chr19:17,824,782...17,847,982
Ensembl chr19:17,824,780...17,848,071
JBrowse link
G JMJD1C jumonji domain containing 1C EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr10:63,167,225...63,521,890
Ensembl chr10:63,167,221...63,521,850
JBrowse link
G KANSL1 KAT8 regulatory NSL complex subunit 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr17:46,029,916...46,225,367
Ensembl chr17:46,029,916...46,225,389
JBrowse link
G KAT6A lysine acetyltransferase 6A EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 8:41,929,479...42,051,987
Ensembl chr 8:41,929,479...42,051,994
JBrowse link
G KDM6A lysine demethylase 6A exacerbates EXP
IAGP
CTD Direct Evidence: marker/mechanism
DNA:mutations:multiple: (human)
DNA:splice-site mutation, missense mutations:splice junction, CDS:multiple: (human)
CTD
RGD
PMID:23685749 PMID:31483290 PMID:23685749 RGD:150429736, RGD:150429732 NCBI chr  X:44,873,188...45,112,779
Ensembl chr  X:44,873,188...45,112,779
JBrowse link
G KDM6B lysine demethylase 6B EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr17:7,834,217...7,854,796
Ensembl chr17:7,834,217...7,854,796
JBrowse link
G KMT2C lysine methyltransferase 2C disease_progression EXP
IAGP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:23685749 PMID:31483290 RGD:150429736 NCBI chr 7:152,134,925...152,436,003
Ensembl chr 7:152,134,922...152,436,644
JBrowse link
G KRAS KRAS proto-oncogene, GTPase IAGP ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:6695174 PMID:12460918 PMID:15696205 PMID:16361624 PMID:16618717 More... NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936
JBrowse link
G KRT15 keratin 15 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr17:41,513,745...41,518,890
Ensembl chr17:41,513,745...41,522,529
JBrowse link
G KRT5 keratin 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr12:52,514,575...52,520,394
Ensembl chr12:52,514,575...52,520,530
JBrowse link
G LRRC56 leucine rich repeat containing 56 IAGP ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr11:506,462...554,912
Ensembl chr11:537,527...554,912
JBrowse link
G MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 3:65,353,526...66,038,918
Ensembl chr 3:65,353,525...66,038,918
JBrowse link
G MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 7:78,017,055...79,453,667
Ensembl chr 7:78,017,055...79,453,667
JBrowse link
G MAML3 mastermind like transcriptional coactivator 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 4:139,716,753...140,154,184
Ensembl chr 4:139,716,753...140,154,184
JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr19:4,090,321...4,124,122
Ensembl chr19:4,090,321...4,124,122
JBrowse link
G MARCKS myristoylated alanine rich protein kinase C substrate EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 6:113,857,345...113,863,475
Ensembl chr 6:113,857,345...113,863,475
JBrowse link
G MARK2 microtubule affinity regulating kinase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr11:63,839,110...63,911,020
Ensembl chr11:63,838,928...63,911,020
JBrowse link
G MECOM MDS1 and EVI1 complex locus IAGP ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar NCBI chr 3:169,083,507...169,663,712
Ensembl chr 3:169,083,499...169,663,775
JBrowse link
G MGA MAX dimerization protein MGA EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr15:41,621,224...41,769,940
Ensembl chr15:41,621,134...41,773,081
JBrowse link
G MIER2 MIER family member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr19:305,573...344,796
Ensembl chr19:305,573...344,815
JBrowse link
G MLC1 modulator of VRAC current 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr22:50,059,391...50,085,875
Ensembl chr22:50,059,391...50,085,426
JBrowse link
G MORF4L1 mortality factor 4 like 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr15:78,872,890...78,898,139
Ensembl chr15:78,810,487...78,898,139
JBrowse link
G MYB MYB proto-oncogene, transcription factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 PMID:26829750 NCBI chr 6:135,181,308...135,219,172
Ensembl chr 6:135,181,308...135,219,173
JBrowse link
G MYBL1 MYB proto-oncogene like 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 8:66,562,175...66,613,218
Ensembl chr 8:66,562,175...66,614,247
JBrowse link
G MYCBP MYC binding protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 1:38,862,490...38,873,378
Ensembl chr 1:38,862,493...38,873,368
JBrowse link
G MYCN MYCN proto-oncogene, bHLH transcription factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 2:15,940,550...15,947,004
Ensembl chr 2:15,940,550...15,947,007
JBrowse link
G NETO2 neuropilin and tolloid like 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr16:47,077,703...47,143,945
Ensembl chr16:47,077,703...47,143,945
JBrowse link
G NFIB nuclear factor I B EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 9:14,081,843...14,532,077
Ensembl chr 9:14,081,843...14,398,983
JBrowse link
G NOTCH1 notch receptor 1 EXP
IAGP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenoid cystic carcinoma
CTD
ClinVar
PMID:23685749 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048
JBrowse link
G NSD1 nuclear receptor binding SET domain protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 5:177,131,798...177,300,213
Ensembl chr 5:177,131,830...177,300,213
JBrowse link
G NTRK3 neurotrophic receptor tyrosine kinase 3 treatment IMP RGD PMID:23027130 RGD:150519921 NCBI chr15:87,859,751...88,256,739
Ensembl chr15:87,859,751...88,256,791
JBrowse link
G PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr  X:48,831,096...48,835,610
Ensembl chr  X:48,831,096...48,835,610
JBrowse link
G PDZK1 PDZ domain containing 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 1:145,670,852...145,707,400
Ensembl chr 1:145,670,852...145,708,148
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha EXP
IAGP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenocystic carcinoma
CTD
ClinVar
PMID:15930273 PMID:17376864 PMID:18074223 PMID:19366826 PMID:22120714 More... NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093
JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 8:47,773,111...47,960,136
Ensembl chr 8:47,773,111...47,960,178
JBrowse link
G PTEN phosphatase and tensin homolog EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930
JBrowse link
G PYGB glycogen phosphorylase B EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr20:25,248,085...25,298,012
Ensembl chr20:25,248,085...25,298,012
JBrowse link
G RBFOX2 RNA binding fox-1 homolog 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr22:35,738,736...36,028,824
Ensembl chr22:35,738,736...36,028,824
JBrowse link
G SERPINF1 serpin family F member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr17:1,762,060...1,777,565
Ensembl chr17:1,762,029...1,777,565
JBrowse link
G SETD2 SET domain containing 2, histone lysine methyltransferase EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 3:47,016,436...47,164,840
Ensembl chr 3:47,016,428...47,164,113
JBrowse link
G SF3B1 splicing factor 3b subunit 1 IAGP ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar PMID:25741868 PMID:26619011 NCBI chr 2:197,389,784...197,435,093
Ensembl chr 2:197,388,515...197,435,079
JBrowse link
G SLC24A3 solute carrier family 24 member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr20:19,212,642...19,722,926
Ensembl chr20:19,212,642...19,722,926
JBrowse link
G SLC3A2 solute carrier family 3 member 2 disease_progression IEP RGD PMID:23516127 RGD:151361211 NCBI chr11:62,856,109...62,888,860
Ensembl chr11:62,856,004...62,888,880
JBrowse link
G SLC7A5 solute carrier family 7 member 5 disease_progression IEP RGD PMID:23516127 RGD:151361211 NCBI chr16:87,830,023...87,869,507
Ensembl chr16:87,830,023...87,869,507
JBrowse link
G SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 EXP
IAGP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenoid cystic carcinoma
CTD
ClinVar
PMID:23685749 NCBI chr 9:2,015,347...2,193,624
Ensembl chr 9:1,980,290...2,193,624
JBrowse link
G SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 IAGP ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar NCBI chr22:23,786,966...23,838,009
Ensembl chr22:23,786,931...23,838,009
JBrowse link
G SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr17:40,624,962...40,647,818
Ensembl chr17:40,624,962...40,648,654
JBrowse link
G SMC1A structural maintenance of chromosomes 1A EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr  X:53,374,149...53,422,728
Ensembl chr  X:53,374,149...53,422,728
JBrowse link
G SON SON DNA and RNA binding protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr21:33,543,038...33,577,481
Ensembl chr21:33,543,038...33,577,481
JBrowse link
G SOX11 SRY-box transcription factor 11 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 2:5,692,384...5,701,385
Ensembl chr 2:5,692,384...5,701,385
JBrowse link
G SOX4 SRY-box transcription factor 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 6:21,593,751...21,598,619
Ensembl chr 6:21,593,751...21,598,619
JBrowse link
G SRCAP Snf2 related CREBBP activator protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr16:30,699,171...30,741,409
Ensembl chr16:30,698,209...30,741,409
JBrowse link
G ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr11:126,355,686...126,414,638
Ensembl chr11:126,355,640...126,440,344
JBrowse link
G STAG3L1 STAG3 cohesin complex component like 1 (pseudogene) EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 7:75,359,200...75,367,809
Ensembl chr 7:75,361,374...75,367,087
JBrowse link
G STAT3 signal transducer and activator of transcription 3 IAGP ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568
JBrowse link
G TLK1 tousled like kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 2:170,990,823...171,231,293
Ensembl chr 2:170,990,823...171,231,314
JBrowse link
G TOP2A DNA topoisomerase II alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896
JBrowse link
G TP53 tumor protein p53 disease_progression IEP
IAGP
EXP
ClinVar Annotator: match by term: Adenocystic carcinoma
ClinVar Annotator: match by term: Adenoid cystic carcinoma
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
RGD
PMID:1673792 PMID:1686725 PMID:6736287 PMID:7707106 PMID:7881428 More... RGD:8547828 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G UHRF1 ubiquitin like with PHD and ring finger domains 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr19:4,903,080...4,962,154
Ensembl chr19:4,903,080...4,962,154
JBrowse link
G VCAN versican EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 5:83,471,744...83,582,302
Ensembl chr 5:83,471,618...83,582,303
JBrowse link
G WNT5B Wnt family member 5B EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr12:1,617,056...1,647,212
Ensembl chr12:1,529,891...1,647,212
JBrowse link
G XAGE1A X antigen family member 1A EXP CTD Direct Evidence: marker/mechanism CTD PMID:24648988 NCBI chr  X:52,495,808...52,500,812
Ensembl chr  X:52,495,808...52,500,812
JBrowse link
G XRN2 5'-3' exoribonuclease 2 IAGP DNA:hypermethylation:3' utr: (human) RGD PMID:21692051 RGD:11041796 NCBI chr20:21,303,331...21,389,825
Ensembl chr20:21,303,331...21,389,825
JBrowse link
G ZIM2 zinc finger imprinted 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr19:56,774,547...56,840,726
Ensembl chr19:56,774,547...56,840,731
JBrowse link
adenoid squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNF1A HNF1 homeobox A ISO RGD PMID:10489374 RGD:150540314 NCBI chr12:120,978,543...121,002,512
Ensembl chr12:120,978,543...121,002,512
JBrowse link
Barrett's adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP26A1 cytochrome P450 family 26 subfamily A member 1 IEP RGD PMID:18059332 RGD:13782259 NCBI chr10:93,073,475...93,077,885
Ensembl chr10:93,073,475...93,077,885
JBrowse link
G GPX3 glutathione peroxidase 3 IDA DNA:hypermethylation
DNA:hypermethylation:promoter
RGD PMID:16229808 PMID:18664505 RGD:151665354, RGD:151665749 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988
JBrowse link
G GPX7 glutathione peroxidase 7 IDA DNA:hypermethylation:promoter RGD PMID:18664505 RGD:151665749 NCBI chr 1:52,602,371...52,609,051
Ensembl chr 1:52,602,371...52,609,051
JBrowse link
congenital heart defects, hamartomas of tongue, and polysyndactyly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WDPCP WD repeat containing planar cell polarity effector IAGP
EXP
ClinVar Annotator: match by term: Heart defect - tongue hamartoma - polysyndactyly syndrome
ClinVar Annotator: match by term: Heart defect - tongue hamartoma - polysyndactyly syndrome | ClinVar Annotator: match by term: WDPCP-related condition
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:9536098 PMID:16199547 PMID:17576681 PMID:20671153 PMID:25326635 More... NCBI chr 2:63,119,559...63,840,826
Ensembl chr 2:63,119,559...63,827,843
JBrowse link
Cutaneous Telangiectasia and Cancer Syndrome, Familial term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATR ATR serine/threonine kinase IAGP
EXP
ClinVar Annotator: match by term: Cutaneous telangiectasia and cancer syndrome, familial
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:9536098 PMID:15987455 PMID:17010193 PMID:17576681 PMID:18414213 More... NCBI chr 3:142,449,235...142,578,733
Ensembl chr 3:142,449,007...142,578,733
JBrowse link
G LOC126806830 BRD4-independent group 4 enhancer GRCh37_chr3:142203676-142204875 IAGP ClinVar Annotator: match by term: Cutaneous telangiectasia and cancer syndrome, familial ClinVar PMID:25741868 PMID:28492532 NCBI chr 3:142,484,834...142,486,033 JBrowse link
G LOC129937703 ATAC-STARR-seq lymphoblastoid active region 20643 IAGP ClinVar Annotator: match by term: Cutaneous telangiectasia and cancer syndrome, familial ClinVar PMID:25741868 PMID:28492532
esophageal cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 IEP protein:increased expression:esophagus (human) RGD PMID:27188433 RGD:152995510 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member IAGP ClinVar Annotator: match by term: Esophageal cancer, alcohol-related, susceptibility to ClinVar PMID:2987944 PMID:4065146 PMID:6650498 PMID:7180842 PMID:7593603 More... NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
JBrowse link
G BHLHE41 basic helix-loop-helix family member e41 IEP protein:increased expression:esophagus(human) RGD PMID:29890466 RGD:151665308 NCBI chr12:26,120,030...26,125,037
Ensembl chr12:26,120,030...26,125,037
JBrowse link
G BRCA2 BRCA2 DNA repair associated IAGP ClinVar Annotator: match by term: Esophagus cancer ClinVar PMID:25741868 PMID:28492532 PMID:31911673 NCBI chr13:32,315,508...32,400,268
Ensembl chr13:32,315,086...32,400,268
JBrowse link
G CTNNA1 catenin alpha 1 disease_progression ISO RGD PMID:9863006 RGD:2289811 NCBI chr 5:138,753,425...138,935,034
Ensembl chr 5:138,610,967...138,935,034
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 ISO protein:increased expression:serum RGD PMID:20232121 RGD:5134997 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 IAGP RGD PMID:11833070 PMID:26782562 RGD:14700950, RGD:11554919 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 ameliorates IEP RNA:decreased expression:esophagus (human) RGD PMID:14760115 RGD:152025255 NCBI chr20:54,143,538...54,173,986
Ensembl chr20:54,153,446...54,173,986
JBrowse link
G DLEC1 DLEC1 cilia and flagella associated protein IAGP ClinVar Annotator: match by term: Esophagus cancer ClinVar PMID:25741868 NCBI chr 3:38,039,208...38,124,025
Ensembl chr 3:38,039,205...38,124,025
JBrowse link
G FGF2 fibroblast growth factor 2 IEP RGD PMID:29660336 RGD:21409755 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236
JBrowse link
G GPX3 glutathione peroxidase 3 treatment IDA DNA:hypermethylation RGD PMID:33292587 RGD:151665781 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988
JBrowse link
G GSTM1 glutathione S-transferase mu 1 IAGP RGD PMID:11833070 PMID:23749488 PMID:12406553 PMID:26782562 RGD:14700950, RGD:14700969, RGD:14700964, RGD:11554919 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTT1 glutathione S-transferase theta 1 IAGP RGD PMID:23749488 RGD:14700969
G HMOX1 heme oxygenase 1 ISO protein:increased expression:esophagus RGD PMID:20498946 RGD:4145286 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G IL10 interleukin 10 treatment IEP RGD PMID:26603620 RGD:152998997 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL1B interleukin 1 beta treatment IEP RGD PMID:26603620 RGD:152998997 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL1R2 interleukin 1 receptor type 2 susceptibility IAGP DNA:SNP:cds:rs11674595|rs2072472 (human) RGD PMID:31744444 RGD:152998961 NCBI chr 2:101,991,960...102,028,544
Ensembl chr 2:101,991,960...102,028,544
JBrowse link
G IL5 interleukin 5 treatment ISO RGD PMID:20232121 RGD:5134997 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838
JBrowse link
G LZTS1 leucine zipper tumor suppressor 1 IAGP esophageal squamous cell carcinoma, OMIM:133239 RGD PMID:10097140 RGD:1600104 NCBI chr 8:20,246,165...20,303,963
Ensembl chr 8:20,246,165...20,303,963
JBrowse link
G MAF MAF bZIP transcription factor IAGP ClinVar Annotator: match by term: Esophagus cancer ClinVar PMID:25741868 PMID:28492532 NCBI chr16:79,202,622...79,600,737
Ensembl chr16:79,585,843...79,600,737
JBrowse link
G MIR155 microRNA 155 IEP RGD PMID:29660336 RGD:21409755 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044
JBrowse link
G MIR21 microRNA 21 IEP RNA:increased expression:esophagus (human)
RNA:increased expression:blood serum (human)
RGD PMID:27188433 PMID:22638884 RGD:152995510, RGD:152998900 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337
JBrowse link
G MXI1 MAX interactor 1, dimerization protein ISO RGD PMID:10849326 RGD:1298988 NCBI chr10:110,207,605...110,287,365
Ensembl chr10:110,207,605...110,287,365
JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor IEP mRNA:splice variants:esophagus (human) RGD PMID:24527027 RGD:150519911 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha IEP protein:increased expression:esophagus (human) RGD PMID:27188433 RGD:152995510 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093
JBrowse link
G PTEN phosphatase and tensin homolog treatment IMP
IEP
human gene and cells in a mouse model
protein:decreased expression:esophagus (human)
RGD PMID:20378992 PMID:27188433 RGD:127285592, RGD:152995510 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930
JBrowse link
G SOCS1 suppressor of cytokine signaling 1 IEP mRNA,protein:decreased expression:esophagus: RGD PMID:33862112 RGD:151232285 NCBI chr16:11,254,417...11,256,204
Ensembl chr16:11,254,417...11,256,204
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 IAGP ClinVar Annotator: match by term: Esophagus cancer ClinVar PMID:7664267 PMID:9395234 PMID:9536098 PMID:10789724 PMID:11212236 More... NCBI chr 3:30,606,356...30,694,142
Ensembl chr 3:30,606,601...30,694,142
JBrowse link
G TNFAIP3 TNF alpha induced protein 3 disease_progression
severity
IAGP DNA:SNP:intron 6: (rs610604) (human)
DNA:SNP:3'utr: (rs583522) (human)
RGD PMID:25354935 PMID:26598072 RGD:151347597, RGD:11075880 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314
JBrowse link
G TP53 tumor protein p53 IAGP ClinVar Annotator: match by term: Esophagus cancer ClinVar PMID:7887414 PMID:8023157 PMID:8118819 PMID:8164043 PMID:8825920 More... NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G WWOX WW domain containing oxidoreductase IAGP ClinVar Annotator: match by term: Esophagus cancer ClinVar PMID:24456803 PMID:25411445 PMID:25741868 PMID:26467025 PMID:28492532 More... NCBI chr16:78,099,654...79,212,667
Ensembl chr16:78,099,400...79,212,667
JBrowse link
G XRCC1 X-ray repair cross complementing 1 susceptibility IAGP DNA:missense mutation:exon 9: p.T304A, c.910A>G (human) RGD PMID:24345911 RGD:150530620 NCBI chr19:43,543,311...43,575,527
Ensembl chr19:43,543,311...43,580,473
JBrowse link
esophageal carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIRC7 baculoviral IAP repeat containing 7 disease_progression HEP mRNA:increased expression:esophagus (human) RGD PMID:31964418 RGD:153344516 NCBI chr20:63,235,905...63,240,495
Ensembl chr20:63,235,883...63,240,495
JBrowse link
G BRCA2 BRCA2 DNA repair associated IAGP ClinVar Annotator: match by term: Carcinoma of esophagus ClinVar PMID:17972177 PMID:18431501 PMID:18627636 PMID:18779604 PMID:21120943 More... NCBI chr13:32,315,508...32,400,268
Ensembl chr13:32,315,086...32,400,268
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A IAGP ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:25741868 PMID:26619011 PMID:28492532 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301
JBrowse link
G CTNNB1 catenin beta 1 IAGP ClinVar Annotator: match by term: Esophageal carcinoma
ClinVar Annotator: match by term: Carcinoma of esophagus | ClinVar Annotator: match by term: Esophageal carcinoma
ClinVar PMID:9065402 PMID:9065403 PMID:9294210 PMID:10027390 PMID:10192393 More... NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G DCC DCC netrin 1 receptor IAGP ClinVar Annotator: match by term: Esophageal carcinoma, somatic ClinVar PMID:8187090 NCBI chr18:52,340,197...53,535,899
Ensembl chr18:52,340,197...53,535,899
JBrowse link
G EGFR epidermal growth factor receptor IAGP ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:15623594 PMID:16205628 PMID:16707764 PMID:16863509 PMID:17653080 More... NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G EGFR-AS1 EGFR antisense RNA 1 IAGP ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:15623594 PMID:16205628 PMID:16707764 PMID:16863509 PMID:17653080 More... NCBI chr 7:55,179,750...55,188,949
Ensembl chr 7:55,179,750...55,188,977
JBrowse link
G EP300 E1A binding protein p300 IAGP ClinVar Annotator: match by term: Carcinoma of esophagus ClinVar PMID:26619011 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,592...41,180,077
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 IAGP ClinVar Annotator: match by term: Carcinoma of esophagus ClinVar PMID:16397024 PMID:23220880 PMID:25157968 PMID:26619011 NCBI chr17:39,688,094...39,728,658
Ensembl chr17:39,687,914...39,730,426
JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 IAGP ClinVar Annotator: match by term: Esophageal carcinoma
ClinVar Annotator: match by term: Carcinoma of esophagus | ClinVar Annotator: match by term: Esophageal carcinoma
ClinVar PMID:25741868 PMID:26619011 NCBI chr 4:152,320,544...152,536,092
Ensembl chr 4:152,320,544...152,536,092
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 IAGP ClinVar Annotator: match by term: Esophageal carcinoma
ClinVar Annotator: match by term: Carcinoma of esophagus
ClinVar PMID:25157968 PMID:26619011 NCBI chr10:121,478,330...121,598,458
Ensembl chr10:121,478,332...121,598,458
JBrowse link
G GRB7 growth factor receptor bound protein 7 exacerbates IEP mRNA:increased expression:esophagus mucosa (human) RGD PMID:8988034 RGD:151347660 NCBI chr17:39,737,938...39,747,285
Ensembl chr17:39,737,927...39,747,291
JBrowse link
G HRAS HRas proto-oncogene, GTPase IAGP ClinVar Annotator: match by term: Esophageal carcinoma
ClinVar Annotator: match by term: Carcinoma of esophagus
ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321
JBrowse link
G HTRA1 HtrA serine peptidase 1 disease_progression IEP mRNA,protein:decreased expression:esophagus (human) RGD PMID:22935172 RGD:152985525 NCBI chr10:122,461,553...122,514,907
Ensembl chr10:122,458,551...122,514,907
JBrowse link
G JAK2 Janus kinase 2 treatment IDA associated with Immune Deficiency Disease, human cells in mouse model RGD PMID:25724470 RGD:127285656 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948
JBrowse link
G KRAS KRAS proto-oncogene, GTPase IAGP ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:16361624 PMID:16618717 PMID:18316791 PMID:19114683 PMID:19679400 More... NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936
JBrowse link
G LOC126806658 BRD4-independent group 4 enhancer GRCh37_chr3:41265899-41267098 IAGP ClinVar Annotator: match by term: Esophageal carcinoma
ClinVar Annotator: match by term: Carcinoma of esophagus | ClinVar Annotator: match by term: Esophageal carcinoma
ClinVar PMID:9065402 PMID:9065403 PMID:9294210 PMID:10027390 PMID:10192393 More... NCBI chr 3:41,224,408...41,225,607 JBrowse link
G LRRC56 leucine rich repeat containing 56 IAGP ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr11:506,462...554,912
Ensembl chr11:537,527...554,912
JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 exacerbates HEP mRNA:decreased expression:espohagus (human) RGD PMID:32831056 RGD:155630592 NCBI chr19:7,903,877...7,914,478
Ensembl chr19:7,903,843...7,914,478
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor IAGP ClinVar Annotator: match by term: Carcinoma of esophagus ClinVar PMID:25157968 PMID:26619011 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha IAGP ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093
JBrowse link
G RHOA ras homolog family member A IAGP ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:26619011 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998
JBrowse link
G SLC7A5 solute carrier family 7 member 5 severity IEP RGD PMID:15906366 RGD:151361282 NCBI chr16:87,830,023...87,869,507
Ensembl chr16:87,830,023...87,869,507
JBrowse link
G SMAD4 SMAD family member 4 IAGP ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:6604412 PMID:8898652 PMID:9214508 PMID:9285566 PMID:9582123 More... NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,528...51,085,045
JBrowse link
G STAT3 signal transducer and activator of transcription 3 treatment IDA associated with Immune Deficiency Disease, human cells in mouse model RGD PMID:25724470 RGD:127285656 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568
JBrowse link
G TP53 tumor protein p53 IAGP ClinVar Annotator: match by term: Esophageal carcinoma
ClinVar Annotator: match by term: Carcinoma of esophagus
ClinVar Annotator: match by term: Carcinoma of esophagus | ClinVar Annotator: match by term: Esophageal carcinoma
ClinVar PMID:124622 PMID:253702 PMID:960674 PMID:1349175 PMID:1359493 More... NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
Esophageal Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21332314 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,043...130,887,675
JBrowse link
G ACTB actin beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902
JBrowse link
G ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide EXP CTD Direct Evidence: marker/mechanism CTD PMID:18500343 NCBI chr 4:99,304,971...99,321,401
Ensembl chr 4:99,304,971...99,321,401
JBrowse link
G ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide EXP CTD Direct Evidence: marker/mechanism CTD PMID:18500343 NCBI chr 4:99,412,263...99,435,342
Ensembl chr 4:99,412,261...99,435,510
JBrowse link
G AKAP13 A-kinase anchoring protein 13 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17068819 NCBI chr15:85,380,603...85,749,358
Ensembl chr15:85,380,571...85,749,358
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member EXP CTD Direct Evidence: marker/mechanism CTD PMID:8850269 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
JBrowse link
G ALOX15 arachidonate 15-lipoxygenase EXP CTD Direct Evidence: marker/mechanism CTD PMID:11406566 NCBI chr17:4,630,919...4,641,678
Ensembl chr17:4,630,919...4,642,294
JBrowse link
G AQP3 aquaporin 3 (Gill blood group) EXP CTD Direct Evidence: marker/mechanism CTD PMID:21401805 NCBI chr 9:33,441,160...33,447,593
Ensembl chr 9:33,441,156...33,447,596
JBrowse link
G BAX BCL2 associated X, apoptosis regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:17634542 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BBC3 BCL2 binding component 3 EXP CTD Direct Evidence: therapeutic CTD PMID:16481741 NCBI chr19:47,220,824...47,232,860
Ensembl chr19:47,220,822...47,232,766
JBrowse link
G BCL2 BCL2 apoptosis regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2A1 BCL2 related protein A1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17634542 NCBI chr15:79,960,892...79,971,196
Ensembl chr15:79,960,892...79,971,196
JBrowse link
G BSG basigin (Ok blood group) EXP CTD Direct Evidence: marker/mechanism CTD PMID:36574092 NCBI chr19:571,283...583,493
Ensembl chr19:571,277...583,494
JBrowse link
G CASP8 caspase 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17450141 PMID:21472143 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
JBrowse link
G CCND1 cyclin D1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12235107 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CCNH cyclin H EXP CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 5:87,311,471...87,412,930
Ensembl chr 5:87,318,416...87,413,029
JBrowse link
G CDH13 cadherin 13 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18729198 NCBI chr16:82,626,969...83,800,640
Ensembl chr16:82,626,965...83,800,640
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A disease_progression IEP RGD PMID:11903577 RGD:8662379 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A ISO
EXP
Protein:decreased expression:esophagus
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:18410530 PMID:10969811 RGD:1600828 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301
JBrowse link
G CRYAB crystallin alpha B EXP CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr11:111,908,564...111,923,740
Ensembl chr11:111,908,564...111,923,722
JBrowse link
G CSF3 colony stimulating factor 3 EXP CTD Direct Evidence: therapeutic CTD PMID:7692001 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813
JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21509778 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601
JBrowse link
G CYP26A1 cytochrome P450 family 26 subfamily A member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18059332 NCBI chr10:93,073,475...93,077,885
Ensembl chr10:93,073,475...93,077,885
JBrowse link
G DCC DCC netrin 1 receptor EXP CTD Direct Evidence: marker/mechanism CTD NCBI chr18:52,340,197...53,535,899
Ensembl chr18:52,340,197...53,535,899
JBrowse link
G EGFR epidermal growth factor receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:21298351 PMID:21468131 PMID:22042947 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G ENO1 enolase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22042947 NCBI chr17:39,688,094...39,728,658
Ensembl chr17:39,687,914...39,730,426
JBrowse link
G FAS Fas cell surface death receptor IEP protein:decreased expression:esophageal mucosa: RGD PMID:9605741 RGD:11049151 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
JBrowse link
G FASLG Fas ligand IEP protein:increased expression:esophageal mucosa: RGD PMID:9605741 RGD:11049151 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase EXP CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374
JBrowse link
G GHRL ghrelin and obestatin prepropeptide EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chr 3:10,285,666...10,292,947
Ensembl chr 3:10,285,666...10,292,947
JBrowse link
G GNG7 G protein subunit gamma 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18219292 NCBI chr19:2,511,219...2,702,694
Ensembl chr19:2,511,219...2,702,694
JBrowse link
G GRIK2 glutamate ionotropic receptor kainate type subunit 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 6:101,393,708...102,070,083
Ensembl chr 6:100,962,701...102,081,622
JBrowse link
G GSTT1 glutathione S-transferase theta 1 susceptibility IAGP DNA:deletion: : RGD PMID:15526353 RGD:5490562
G KDR kinase insert domain receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472143 PMID:35917945 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595
JBrowse link
G LGALS3 galectin 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17634542 NCBI chr14:55,129,252...55,145,430
Ensembl chr14:55,124,110...55,145,423
JBrowse link
G LZTS1 leucine zipper tumor suppressor 1 EXP CTD Direct Evidence: marker/mechanism CTD NCBI chr 8:20,246,165...20,303,963
Ensembl chr 8:20,246,165...20,303,963
JBrowse link
G MACIR macrophage immunometabolism regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 5:103,258,374...103,278,660
Ensembl chr 5:103,258,763...103,278,660
JBrowse link
G MAP3K3 mitogen-activated protein kinase kinase kinase 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17068819 NCBI chr17:63,622,417...63,696,305
Ensembl chr17:63,622,415...63,696,305
JBrowse link
G MARCHF8 membrane associated ring-CH-type finger 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17068819 NCBI chr10:45,454,585...45,594,907
Ensembl chr10:45,454,585...45,594,906
JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:22042947 NCBI chr 7:116,672,196...116,798,377
Ensembl chr 7:116,672,196...116,798,377
JBrowse link
G MIR145 microRNA 145 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21248297 NCBI chr 5:149,430,646...149,430,733
Ensembl chr 5:149,430,646...149,430,733
JBrowse link
G MIR200C microRNA 200c EXP CTD Direct Evidence: marker/mechanism CTD PMID:21248297 NCBI chr12:6,963,699...6,963,766
Ensembl chr12:6,963,699...6,963,766
JBrowse link
G MIR21 microRNA 21 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21248297 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337
JBrowse link
G MIR98 microRNA 98 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27270317 NCBI chr  X:53,556,223...53,556,341
Ensembl chr  X:53,556,223...53,556,341
JBrowse link
G MLH3 mutL homolog 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16981255 NCBI chr14:75,013,775...75,051,467
Ensembl chr14:75,013,769...75,051,532
JBrowse link
G MMP14 matrix metallopeptidase 14 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chr14:22,836,585...22,847,758
Ensembl chr14:22,836,560...22,849,041
JBrowse link
G MT1G metallothionein 1G EXP CTD Direct Evidence: marker/mechanism CTD PMID:17068819 NCBI chr16:56,666,730...56,668,065
Ensembl chr16:56,666,730...56,668,065
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor treatment ISO RGD PMID:22844359 RGD:7207890 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G NOS2 nitric oxide synthase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15264214 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NOS3 nitric oxide synthase 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21977915 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487
JBrowse link
G PHB1 prohibitin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr17:49,404,052...49,414,882
Ensembl chr17:49,404,049...49,414,905
JBrowse link
G PRDX1 peroxiredoxin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,510,914...45,542,732
JBrowse link
G PRDX2 peroxiredoxin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr19:12,796,823...12,801,800
Ensembl chr19:12,796,820...12,801,800
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12189197 NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 susceptibility IAGP
EXP
ISO
DNA:SNPs: :-1195A > G, -765G > C (human)
CTD Direct Evidence: marker/mechanism
mRNA,protein:increased expression:Esophagus
CTD
RGD
PMID:11059772 PMID:16322294 PMID:17707579 PMID:16083713 PMID:22165968 RGD:5135528, RGD:5687745 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G RNF6 ring finger protein 6 EXP CTD Direct Evidence: marker/mechanism CTD NCBI chr13:26,132,115...26,223,085
Ensembl chr13:26,132,115...26,222,314
JBrowse link
G RPRM reprimo, TP53 dependent G2 arrest mediator homolog EXP CTD Direct Evidence: marker/mechanism CTD PMID:17121882 NCBI chr 2:153,477,338...153,478,762
Ensembl chr 2:153,477,338...153,478,762
JBrowse link
G RUNX3 RUNX family transcription factor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18058463 NCBI chr 1:24,899,511...24,965,138
Ensembl chr 1:24,899,511...24,965,121
JBrowse link
G SERPINB3 serpin family B member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr18:63,655,197...63,661,893
Ensembl chr18:63,655,197...63,661,893
JBrowse link
G SFN stratifin EXP CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr 1:26,863,149...26,864,456
Ensembl chr 1:26,863,149...26,864,456
JBrowse link
G SLC30A7 solute carrier family 30 member 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17068819 NCBI chr 1:100,896,090...100,996,078
Ensembl chr 1:100,896,076...100,981,757
JBrowse link
G SMYD2 SET and MYND domain containing 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25825497 NCBI chr 1:214,281,159...214,337,131
Ensembl chr 1:214,281,102...214,337,131
JBrowse link
G SNAI2 snail family transcriptional repressor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17068819 NCBI chr 8:48,917,598...48,921,429
Ensembl chr 8:48,917,598...48,921,740
JBrowse link
G SOD2 superoxide dismutase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:11053990 PMID:15986332 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SST somatostatin EXP CTD Direct Evidence: marker/mechanism CTD PMID:17999418 NCBI chr 3:187,668,912...187,670,394
Ensembl chr 3:187,668,912...187,670,394
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:10789724 NCBI chr 3:30,606,356...30,694,142
Ensembl chr 3:30,606,601...30,694,142
JBrowse link
G TGM2 transglutaminase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17068819 NCBI chr20:38,127,385...38,168,475
Ensembl chr20:38,127,385...38,166,578
JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chr 8:23,190,452...23,225,102
Ensembl chr 8:23,190,452...23,225,102
JBrowse link
G TP53 tumor protein p53 ISO
EXP
CTD Direct Evidence: marker/mechanism
protein:increased expression:esophageal mucosa:
CTD
RGD
PMID:12706858 PMID:17634542 PMID:26192916 PMID:16778087 PMID:26439224 RGD:8547873, RGD:11075085 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TPM1 tropomyosin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr15:63,042,747...63,071,915
Ensembl chr15:63,042,620...63,071,915
JBrowse link
G TPM4 tropomyosin 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr19:16,067,538...16,103,002
Ensembl chr19:16,067,021...16,103,002
JBrowse link
G TRMT11 tRNA methyltransferase 11 homolog EXP CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 6:125,986,540...126,272,343
Ensembl chr 6:125,986,479...126,203,817
JBrowse link
G TUFM Tu translation elongation factor, mitochondrial EXP CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr16:28,842,411...28,846,348
Ensembl chr16:28,842,411...28,846,348
JBrowse link
G UCHL1 ubiquitin C-terminal hydrolase L1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15930319 NCBI chr 4:41,256,928...41,268,455
Ensembl chr 4:41,256,413...41,268,455
JBrowse link
G WIF1 WNT inhibitory factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17384664 NCBI chr12:65,050,626...65,121,305
Ensembl chr12:65,050,626...65,121,305
JBrowse link
G WWOX WW domain containing oxidoreductase EXP CTD Direct Evidence: marker/mechanism CTD NCBI chr16:78,099,654...79,212,667
Ensembl chr16:78,099,400...79,212,667
JBrowse link
G XIAP X-linked inhibitor of apoptosis EXP CTD Direct Evidence: marker/mechanism CTD PMID:17611394 NCBI chr  X:123,859,708...123,913,972
Ensembl chr  X:123,859,712...123,913,972
JBrowse link
G XRCC3 X-ray repair cross complementing 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21347786 NCBI chr14:103,697,617...103,715,451
Ensembl chr14:103,697,609...103,715,504
JBrowse link
G ZNF667-AS1 ZNF667 antisense RNA 1 (head to head) EXP CTD Direct Evidence: marker/mechanism CTD PMID:29707199 NCBI chr19:56,477,874...56,495,437
Ensembl chr19:56,477,250...56,504,362
JBrowse link
esophagus adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase onset IAGP DNA:SNP:3'utr: (rs4740363) (human) RGD PMID:21472143 RGD:126925218 NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,043...130,887,675
JBrowse link
G ARID1A AT-rich interaction domain 1A disease_progression EXP
IEP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:23525077 PMID:31906887 RGD:127285649 NCBI chr 1:26,696,015...26,782,104
Ensembl chr 1:26,693,236...26,782,104
JBrowse link
G BARX1 BARX homeobox 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24121790 NCBI chr 9:93,951,627...93,955,355
Ensembl chr 9:93,951,627...93,955,355
JBrowse link
G BCL2 BCL2 apoptosis regulator onset IAGP DNA:SNPs:3'utr: (rs720321, rs17757541) (human) RGD PMID:21472143 RGD:126925218 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BECN1 beclin 1 IEP RGD PMID:22301112 RGD:11561943 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 treatment IDA RGD PMID:26291056 RGD:152999007 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403
JBrowse link
G CASP8 caspase 8 onset IAGP DNA:SNP:5'utr: (rs1035142) (human) RGD PMID:21472143 RGD:126925218 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
JBrowse link
G CDC5L cell division cycle 5 like disease_progression IEP protein:increased expression:esophageal mucosa (human) RGD PMID:15725809 RGD:10047052 NCBI chr 6:44,387,706...44,450,425
Ensembl chr 6:44,387,706...44,450,425
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A EXP CTD Direct Evidence: marker/mechanism CTD PMID:23525077 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301
JBrowse link
G CRTC1 CREB regulated transcription coactivator 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24121790 NCBI chr19:18,683,680...18,782,333
Ensembl chr19:18,683,678...18,782,333
JBrowse link
G CTSB cathepsin B IEP RGD PMID:9770500 RGD:734853 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533
JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 onset IAGP DNA:SNP:5'utr: (rs2445762) (human) RGD PMID:21472143 RGD:126925218 NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601
JBrowse link
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 treatment IEP mRNA:increased expression:esophagus (human) RGD PMID:30187205 RGD:151665176 NCBI chr20:54,143,538...54,173,986
Ensembl chr20:54,153,446...54,173,986
JBrowse link
G DOCK2 dedicator of cytokinesis 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23525077 NCBI chr 5:169,637,275...170,083,382
Ensembl chr 5:169,637,268...170,083,382
JBrowse link
G ELMO1 engulfment and cell motility 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23525077 NCBI chr 7:36,852,906...37,449,326
Ensembl chr 7:36,852,906...37,449,223
JBrowse link
G EMX2 empty spiracles homeobox 2 IEP protein:decreased expression:esophagus (human) RGD PMID:31432154 RGD:153323302 NCBI chr10:117,542,746...117,549,546
Ensembl chr10:117,542,445...117,549,546
JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit susceptibility IAGP DNA:snps:cds, 3' utr:c.354C>T, c.8092C>A (human) RGD PMID:18478337 RGD:13207314 NCBI chr19:45,407,334...45,451,547
Ensembl chr19:45,407,334...45,478,828
JBrowse link
G FAS Fas cell surface death receptor IEP associated with Barrett Esophagus;protein:increased expression:esophageal mucosa (human) RGD PMID:10340890 RGD:8662425 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
JBrowse link
G FOXA1 forkhead box A1 IEP protein:increased expression:esophagus RGD PMID:12234996 RGD:151665758 NCBI chr14:37,589,552...37,595,249
Ensembl chr14:37,589,552...37,596,059
JBrowse link
G FOXP1 forkhead box P1 IAGP
EXP
DNA:snps:intron, enhancer:g.70959438A>G, g.70879779A>C (rs9837992, rs2687201) (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:24121790 PMID:26383589 RGD:11535321 NCBI chr 3:70,954,708...71,583,978
Ensembl chr 3:70,954,693...71,583,978
JBrowse link
G GHRL ghrelin and obestatin prepropeptide onset IAGP DNA:SNP:5'utr: (rs696217) (human) RGD PMID:21472143 RGD:126925218 NCBI chr 3:10,285,666...10,292,947
Ensembl chr 3:10,285,666...10,292,947
JBrowse link
G GPX3 glutathione peroxidase 3 susceptibility IAGP DNA:SNPs:intron: (rs4958872, rs3792797) (human) RGD PMID:22715394 RGD:152995500 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988
JBrowse link
G GRB7 growth factor receptor bound protein 7 exacerbates
treatment
IMP
IDA
human cells in a mouse model RGD PMID:32737994 PMID:31809243 RGD:151347656, RGD:151347659 NCBI chr17:39,737,938...39,747,285
Ensembl chr17:39,737,927...39,747,291
JBrowse link
G GSTM1 glutathione S-transferase mu 1 IAGP DNA:deletion:: (human) RGD PMID:17064856 RGD:12792242 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTT1 glutathione S-transferase theta 1 IAGP DNA:deletion:: (human) RGD PMID:17064856 RGD:12792242
G KDR kinase insert domain receptor onset IAGP DNA:SNP:5'utr: (rs11941492) (human) RGD PMID:21472143 RGD:126925218 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595
JBrowse link
G MIR21 microRNA 21 disease_progression IEP RGD PMID:26481465 RGD:41404702 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337
JBrowse link
G MMP1 matrix metallopeptidase 1 susceptibility IAGP DNA:insertion:promoter:g.-1607insG rs1799750 (human) RGD PMID:19321798 RGD:7207058 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160
JBrowse link
G MMP12 matrix metallopeptidase 12 IAGP DNA:snp:promoter:g.-82A>G rs2276109 (human) RGD PMID:19321798 RGD:7207058 NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982
JBrowse link
G MMP14 matrix metallopeptidase 14 onset IAGP DNA:SNP:5'utr: (rs2236302) (human) RGD PMID:21472143 RGD:126925218 NCBI chr14:22,836,585...22,847,758
Ensembl chr14:22,836,560...22,849,041
JBrowse link
G MMP3 matrix metallopeptidase 3 IAGP DNA:insertion:promoter:g.-1613insA rs3025058 (human) RGD PMID:19321798 RGD:7207058 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609
JBrowse link
G MMP9 matrix metallopeptidase 9 IEP protein:increased expression:esophagus RGD PMID:25562781 RGD:13204790 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G NELL1 neural EGFL like 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17452981 NCBI chr11:20,669,551...21,575,686
Ensembl chr11:20,669,551...21,575,686
JBrowse link
G NOS3 nitric oxide synthase 3 onset IAGP DNA:SNP:3'utr: (rs2070744) (human) RGD PMID:21472143 RGD:126925218 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:23525077 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO mRNA,protein:increased expression:Esophagus RGD PMID:22165968 RGD:5687745 NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 disease_progression IEP
EXP
protein: increased expression: esophagus
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:12507933 PMID:12055587 RGD:13207437 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G SLC22A18 solute carrier family 22 member 18 disease_progression IDA DNA:hypermethylation: (human) RGD PMID:23243219 RGD:150557426 NCBI chr11:2,899,691...2,925,246
Ensembl chr11:2,899,721...2,925,246
JBrowse link
G SMAD4 SMAD family member 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23525077 PMID:24952744 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,528...51,085,045
JBrowse link
G SMO smoothened, frizzled class receptor treatment ISO RGD PMID:23108119 RGD:150340553 NCBI chr 7:129,188,633...129,213,545
Ensembl chr 7:129,188,633...129,213,545
JBrowse link
G SOD2 superoxide dismutase 2 ISO RGD PMID:17785574 RGD:2317403 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SPART spartin EXP CTD Direct Evidence: marker/mechanism CTD PMID:23525077 NCBI chr13:36,301,638...36,370,180
Ensembl chr13:36,301,638...36,370,180
JBrowse link
G TLR4 toll like receptor 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23525077 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a onset IAGP DNA:SNP:3'utr: (rs11775256) (human) RGD PMID:21472143 RGD:126925218 NCBI chr 8:23,190,452...23,225,102
Ensembl chr 8:23,190,452...23,225,102
JBrowse link
G TP53 tumor protein p53 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23525077 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G VDR vitamin D receptor susceptibility
disease_progression
IAGP
IEP
DNA:SNPs,haplotype:exon:rs1989969,rs2238135 (human)
DNA:amplication: :
RGD PMID:25910066 PMID:24951052 PMID:24951052 RGD:11055189, RGD:13432070, RGD:13432070 NCBI chr12:47,841,537...47,904,994
Ensembl chr12:47,841,537...47,943,048
JBrowse link
esophagus small cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KRT14 keratin 14 ISO protein:increased expression:esophagus RGD PMID:16140947 RGD:1600174 NCBI chr17:41,582,279...41,586,895
Ensembl chr17:41,582,279...41,586,895
JBrowse link
esophagus squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC2 ATP binding cassette subfamily C member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21206495 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594
JBrowse link
G ADCYAP1 adenylate cyclase activating polypeptide 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr18:904,411...912,172
Ensembl chr18:904,871...912,172
JBrowse link
G ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide EXP CTD Direct Evidence: marker/mechanism CTD PMID:22960999 NCBI chr 4:99,304,971...99,321,401
Ensembl chr 4:99,304,971...99,321,401
JBrowse link
G AJUBA ajuba LIM protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr14:22,971,177...22,982,551
Ensembl chr14:22,971,177...22,982,551
JBrowse link
G AKT1 AKT serine/threonine kinase 1 disease_progression IEP protein:increased expression:esophagus (human) RGD PMID:32642408 RGD:152995512 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member EXP CTD Direct Evidence: marker/mechanism CTD PMID:16639733 PMID:22960999 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
JBrowse link
G ANXA1 annexin A1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393
JBrowse link
G ATM ATM serine/threonine kinase disease_progression IEP Smoke Inhalation Injury; mRNA:increased expression:esophagus (human) RGD PMID:17019709 RGD:150340713 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,823...108,369,102
JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25129146 NCBI chr17:7,646,627...7,657,770
Ensembl chr17:7,646,627...7,657,770
JBrowse link
G AXIN1 axin 1 disease_progression IEP protein:decreased expression:esophagus (human) RGD PMID:12771989 RGD:150530473 NCBI chr16:287,440...352,723
Ensembl chr16:287,440...352,723
JBrowse link
G AZGP1 alpha-2-glycoprotein 1, zinc-binding disease_progression IEP RGD PMID:28053542 RGD:153350138 NCBI chr 7:99,966,730...99,976,031
Ensembl chr 7:99,966,720...99,976,042
JBrowse link
G AZIN1 antizyme inhibitor 1 IMP RGD PMID:24302582 RGD:14700707 NCBI chr 8:102,826,302...102,864,200
Ensembl chr 8:102,826,111...102,893,864
JBrowse link
G B2M beta-2-microglobulin EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr15:44,711,517...44,718,145
Ensembl chr15:44,711,358...44,718,851
JBrowse link
G BLVRB biliverdin reductase B EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr19:40,447,768...40,465,745
Ensembl chr19:40,447,765...40,465,764
JBrowse link
G BMI1 BMI1 proto-oncogene, polycomb ring finger IEP RGD PMID:21165554 RGD:126781701 NCBI chr10:22,321,099...22,331,484
Ensembl chr10:22,321,099...22,331,484
JBrowse link
G BMP6 bone morphogenetic protein 6 IEP protein:increased expression:esophagus RGD PMID:22364398 RGD:7242413 NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728
JBrowse link
G BRCA1 BRCA1 DNA repair associated IAGP DNA:SNP: :rs799917 (human) RGD PMID:23749772 RGD:126925960 NCBI chr17:43,044,295...43,170,327
Ensembl chr17:43,044,295...43,170,245
JBrowse link
G BRCA2 BRCA2 DNA repair associated IAGP DNA:nonsense mutation: :p.K3326X (human) RGD PMID:21279724 RGD:11344913 NCBI chr13:32,315,508...32,400,268
Ensembl chr13:32,315,086...32,400,268
JBrowse link
G BST2 bone marrow stromal cell antigen 2 disease_progression IEP RGD PMID:26832883 RGD:14398496 NCBI chr19:17,402,939...17,405,630
Ensembl chr19:17,402,939...17,405,630
JBrowse link
G BUB1B BUB1 mitotic checkpoint serine/threonine kinase B EXP CTD Direct Evidence: marker/mechanism CTD PMID:18691855 NCBI chr15:40,161,069...40,221,123
Ensembl chr15:40,161,023...40,221,123
JBrowse link
G CA1 carbonic anhydrase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 8:85,327,608...85,378,113
Ensembl chr 8:85,327,608...85,379,014
JBrowse link
G CA12 carbonic anhydrase 12 severity IEP RGD PMID:26316888 RGD:155226859 NCBI chr15:63,321,378...63,381,846
Ensembl chr15:63,321,378...63,381,846
JBrowse link
G CA2 carbonic anhydrase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 8:85,464,007...85,481,493
Ensembl chr 8:85,463,968...85,481,493
JBrowse link
G CALR calreticulin ameliorates EXP
IMP
CTD Direct Evidence: marker/mechanism
human cells in a mouse model
CTD
RGD
PMID:21517111 PMID:19684620 PMID:23814025 RGD:150521703, RGD:150521679 NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489
JBrowse link
G CAPZA1 capping actin protein of muscle Z-line subunit alpha 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 1:112,619,832...112,671,616
Ensembl chr 1:112,619,805...112,671,616
JBrowse link
G CASP8 caspase 8 exacerbates IEP mRNA,protein:decreased expression:esophagus squamous epithelium (human) RGD PMID:31885720 RGD:153300949 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
JBrowse link
G CBX8 chromobox 8 severity IEP mRNA:increased expression:esophagus: RGD PMID:25197352 RGD:9587436 NCBI chr17:79,792,132...79,797,077
Ensembl chr17:79,792,132...79,801,683
JBrowse link
G CCHCR1 coiled-coil alpha-helical rod protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chr 6:31,142,439...31,158,197
Ensembl chr 6:31,142,439...31,158,238
JBrowse link
G CCND1 cyclin D1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A EXP CTD Direct Evidence: therapeutic CTD PMID:15375580 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A EXP CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301
JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B IAGP DNA:SNPs: :rs615552, rs573687 (human) RGD PMID:23361049 RGD:7248756 NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305
JBrowse link
G CFL1 cofilin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026
JBrowse link
G CHRNA5 cholinergic receptor nicotinic alpha 5 subunit susceptibility IAGP
IEP
DNA:SNP: :rs667282(human)
mRNA:increased expression:esophagus (human)
RGD PMID:23844051 PMID:27610024 RGD:150524358, RGD:151361143 NCBI chr15:78,565,520...78,595,269
Ensembl chr15:78,565,520...78,595,269
JBrowse link
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit exacerbates
disease_progression
IEP
IDA
mRNA:increased expression:esophagus (human) RGD PMID:27610024 PMID:33603170 PMID:33603170 RGD:151361143, RGD:151667905, RGD:151667905 NCBI chr15:32,030,483...32,173,018
Ensembl chr15:31,923,438...32,173,018
JBrowse link
G CHRNB4 cholinergic receptor nicotinic beta 4 subunit IEP mRNA:increased expression:esophagus (human) RGD PMID:27610024 RGD:151361143 NCBI chr15:78,624,111...78,661,641
Ensembl chr15:78,624,111...78,727,754
JBrowse link
G CLIC1 chloride intracellular channel 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 6:31,730,581...31,737,318
Ensembl chr 6:31,730,581...31,739,763
JBrowse link
G CLPTM1L CLPTM1 like susceptibility
no_association
IAGP
IEP
DNA:SNP: :rs451360(human)
DNA:SNP: :rs401681(human)
mRNA:increased expression:esophagus
RGD PMID:26716642 PMID:24386361 PMID:25480402 PMID:25007268 RGD:11572962, RGD:150537098, RGD:150530497, RGD:150530488 NCBI chr 5:1,317,752...1,345,099
Ensembl chr 5:1,317,752...1,345,099
JBrowse link
G COL14A1 collagen type XIV alpha 1 chain disease_progression IDA DNA:hypermethylation RGD PMID:25050929 RGD:151665741 NCBI chr 8:120,124,454...120,373,573
Ensembl chr 8:120,059,780...120,373,573
JBrowse link
G CRABP1 cellular retinoic acid binding protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17438526 NCBI chr15:78,340,353...78,348,225
Ensembl chr15:78,340,353...78,348,225
JBrowse link
G CREBBP CREB binding protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713
JBrowse link
G CSF1R colony stimulating factor 1 receptor HEP mRNA:decreased expression:esophagus squamous epithelium (human) RGD PMID:32038997 RGD:150524298 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372
JBrowse link
G CSTB cystatin B EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr21:43,773,950...43,776,308
Ensembl chr21:43,772,511...43,776,330
JBrowse link
G CTNNB1 catenin beta 1 IAGP ClinVar Annotator: match by term: Esophageal squamous cell carcinoma ClinVar PMID:25157968 PMID:25741868 PMID:26619011 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 severity IEP mRNA:increased expression:esophagus (human) RGD PMID:31423201 RGD:150520019 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 disease_progression IEP protein:increased expression:esophagus squamous epithelium (human) RGD PMID:17171785 RGD:152023646 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 IAGP RGD PMID:11860825 RGD:14700943 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 ISO protein:increased expression:esophagus (rat) RGD PMID:18618592 RGD:7829715 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
JBrowse link
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 susceptibility IAGP DNA:SNP:CDS: (rs2296241) (human) RGD PMID:28362172 RGD:151665500 NCBI chr20:54,143,538...54,173,986
Ensembl chr20:54,153,446...54,173,986
JBrowse link
G CYP26B1 cytochrome P450 family 26 subfamily B member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chr 2:72,129,238...72,147,862
Ensembl chr 2:72,129,238...72,147,862
JBrowse link
G CYP2A6 cytochrome P450 family 2 subfamily A member 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:11241319 NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447
JBrowse link
G DAB2IP DAB2 interacting protein severity IEP protein:decreased expression:esophagus (human) RGD PMID:30464518 RGD:151665168 NCBI chr 9:121,567,074...121,785,530
Ensembl chr 9:121,567,057...121,785,530
JBrowse link
G DCC DCC netrin 1 receptor IAGP DNA:deletions:multiple (human) OMIM
RGD
PMID:8187090 RGD:734879 NCBI chr18:52,340,197...53,535,899
Ensembl chr18:52,340,197...53,535,899
JBrowse link
G DIDO1 death inducer-obliterator 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30431698 NCBI chr20:62,877,743...62,937,904
Ensembl chr20:62,877,738...62,937,952
JBrowse link
G DNMT3B DNA methyltransferase 3 beta disease_progression IEP protein:increased expression:nucleus: RGD PMID:22213175 RGD:9589085 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359
JBrowse link
G DPP4 dipeptidyl peptidase 4 IEP protein:increased expression: esophagus RGD PMID:24789592 RGD:152600903 NCBI chr 2:161,992,245...162,074,215
Ensembl chr 2:161,992,245...162,074,394
JBrowse link
G EFNB2 ephrin B2 severity
exacerbates
ameliorates
IEP
IMP
mRNA:increased expression:esophagus squamous epithelium (human)
mRNA,protein:increased expression:esophagus squamous epithelium (human)
human cells in mouse model
RGD PMID:17611172 PMID:31885720 PMID:29190834 RGD:153300947, RGD:153300949, RGD:153300948 NCBI chr13:106,489,745...106,535,662
Ensembl chr13:106,489,745...106,535,662
JBrowse link
G EGFR epidermal growth factor receptor severity IEP
EXP
IAGP
protein:increased expression:esophagus (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Esophageal squamous cell carcinoma
CTD
ClinVar
RGD
PMID:21947696 PMID:23485129 PMID:25157968 PMID:10385363 RGD:5131486 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G EHMT1 euchromatic histone lysine methyltransferase 1 disease_progression IEP protein:increased expression:esophagus:
protein:increased expression:esophagus mucosa:
RGD PMID:24649311 PMID:24805087 RGD:9589143, RGD:9590071 NCBI chr 9:137,619,005...137,836,127
Ensembl chr 9:137,618,992...137,870,016
JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 disease_progression IEP protein:increased expression:esophagus mucosa: RGD PMID:24805087 RGD:9590071 NCBI chr 6:31,879,759...31,897,698
Ensembl chr 6:31,879,759...31,897,698
JBrowse link
G EP300 E1A binding protein p300 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17965222 PMID:25151357 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,592...41,180,077
JBrowse link
G EPB41L3 erythrocyte membrane protein band 4.1 like 3 disease_progression IDA DNA:hypermethylation RGD PMID:25050929 RGD:151665741 NCBI chr18:5,392,386...5,630,663
Ensembl chr18:5,392,381...5,630,700
JBrowse link
G EPHB4 EPH receptor B4 exacerbates IEP mRNA,protein:increased expression:esophagus squamous epithelium (human) RGD PMID:31885720 RGD:153300949 NCBI chr 7:100,802,565...100,827,523
Ensembl chr 7:100,802,565...100,827,523
JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 susceptibility
disease_progression
IAGP
IEP
DNA:SNPs, haplotypes: :rs1595066 and rs16845990 (human)
protein:altered localization:nucleus
RGD PMID:24916311 PMID:18000820 RGD:126781764, RGD:126781765 NCBI chr 2:211,375,717...212,538,802
Ensembl chr 2:211,375,717...212,538,841
JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit treatment IEP RGD PMID:23263828 RGD:11252162 NCBI chr19:45,407,334...45,451,547
Ensembl chr19:45,407,334...45,478,828
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit disease_progression IEP RGD PMID:25613619 PMID:21165554 RGD:126781697, RGD:126781701 NCBI chr 7:148,807,383...148,884,291
Ensembl chr 7:148,807,257...148,884,321
JBrowse link
G FANCA FA complementation group A IAGP DNA:missense mutation: :p.S858R (human) RGD PMID:21279724 RGD:11344913 NCBI chr16:89,737,549...89,816,647
Ensembl chr16:89,726,683...89,816,977
JBrowse link
G FAP fibroblast activation protein alpha IEP protein:increased expression: esophagus RGD PMID:24789592 RGD:152600903 NCBI chr 2:162,170,684...162,243,445
Ensembl chr 2:162,170,684...162,245,151
JBrowse link
G FASN fatty acid synthase EXP CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294
JBrowse link
G FAT1 FAT atypical cadherin 1 EXP
IEP
IMP
HEP
CTD Direct Evidence: marker/mechanism
protein:decreased expression:esophagus squamous epithelium (human)
protein:decreased expression:esophagus squamous epithelium (human)
CTD
RGD
PMID:25151357 PMID:29365412 PMID:24590895 PMID:24590895 RGD:151347646, RGD:151347630, RGD:151347630 NCBI chr 4:186,587,794...186,726,696
Ensembl chr 4:186,587,794...186,726,722
JBrowse link
G FAT2 FAT atypical cadherin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 5:151,504,092...151,594,819
Ensembl chr 5:151,504,092...151,591,331
JBrowse link
G FAT3 FAT atypical cadherin 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr11:92,224,818...92,896,473
Ensembl chr11:92,224,818...92,896,473
JBrowse link
G FAT4 FAT atypical cadherin 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 4:125,314,955...125,492,932
Ensembl chr 4:125,314,918...125,492,932
JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 4:152,320,544...152,536,092
Ensembl chr 4:152,320,544...152,536,092
JBrowse link
G FES FES proto-oncogene, tyrosine kinase exacerbates IDA DNA:hypermethylation: (human) RGD PMID:24936140 RGD:153323298 NCBI chr15:90,884,504...90,895,776
Ensembl chr15:90,883,695...90,895,776
JBrowse link
G FGFR4 fibroblast growth factor receptor 4 treatment IAGP RGD PMID:25989802 RGD:150520041 NCBI chr 5:177,086,915...177,098,144
Ensembl chr 5:177,086,905...177,098,144
JBrowse link
G FKBP1A FKBP prolyl isomerase 1A EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr20:1,368,978...1,393,054
Ensembl chr20:1,368,977...1,393,164
JBrowse link
G FOXA1 forkhead box A1 onset IAGP
IEP
DNA:SNPs: :rs12894364 C>T, rs2145146 C>A (human) RGD PMID:27050876 PMID:29788741 RGD:151665743, RGD:151665759 NCBI chr14:37,589,552...37,595,249
Ensembl chr14:37,589,552...37,596,059
JBrowse link
G FUBP1 far upstream element binding protein 1 exacerbates IEP protein:increased expression:esophagus (human)
mRNA:increased expression:esophagus (human)
RGD PMID:26490982 PMID:32481602 RGD:151361192, RGD:151361197 NCBI chr 1:77,944,055...77,979,501
Ensembl chr 1:77,944,055...77,979,110
JBrowse link
G GDI2 GDP dissociation inhibitor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr10:5,765,223...5,813,434
Ensembl chr10:5,765,223...5,842,132
JBrowse link
G GLO1 glyoxalase I EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 6:38,675,925...38,703,145
Ensembl chr 6:38,675,925...38,703,145
JBrowse link
G GPX3 glutathione peroxidase 3 disease_progression IDA
HDA
DNA:hypermethylation RGD PMID:30018730 PMID:25050929 PMID:20725785 RGD:151665494, RGD:151665741, RGD:151665495 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988
JBrowse link
G GRB7 growth factor receptor bound protein 7 exacerbates IEP
HEP
protein:increased expression:esophagus (human)
mRNA:increased expression:esophagus mucosa (human)
RGD PMID:10797316 PMID:26465158 RGD:151347654, RGD:151347661 NCBI chr17:39,737,938...39,747,285
Ensembl chr17:39,737,927...39,747,291
JBrowse link
G GSTM1 glutathione S-transferase mu 1 no_association IAGP RGD PMID:11860825 PMID:17916905 PMID:25432134 RGD:14700943, RGD:14700982, RGD:14700948 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTO1 glutathione S-transferase omega 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr10:104,254,173...104,267,455
Ensembl chr10:104,235,356...104,267,459
JBrowse link
G GSTP1 glutathione S-transferase pi 1 IAGP DNA:polymorphism: :p.I105V (human) RGD PMID:17916905 RGD:14700982 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
JBrowse link
G GSTT1 glutathione S-transferase theta 1 IAGP
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:17173682 PMID:25432134 PMID:17916905 RGD:14700948, RGD:14700982
G H19 H19 imprinted maternally expressed transcript EXP CTD Direct Evidence: marker/mechanism CTD PMID:32739445 NCBI chr11:1,995,176...2,001,466
Ensembl chr11:1,995,166...2,004,552
JBrowse link
G H2BC14 H2B clustered histone 14 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 6:27,815,022...27,815,489
Ensembl chr 6:27,815,022...27,815,489
JBrowse link
G HEIH hepatocellular carcinoma up-regulated EZH2-associated long non-coding RNA exacerbates IEP mRNA:increased expression:esophagus squamous epithelium (human) RGD PMID:32449803 RGD:153345544 NCBI chr 5:180,829,954...180,831,618
Ensembl chr 5:180,826,871...180,831,621
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:17201171 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G HMGB1 high mobility group box 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597
JBrowse link
G HMGN5 high mobility group nucleosome binding domain 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28914995 NCBI chr  X:81,113,699...81,201,913
Ensembl chr  X:81,113,699...81,201,913
JBrowse link
G HOXB7 homeobox B7 severity IEP protein:increased expression:esophageal mucosa (human) RGD PMID:26076456 RGD:10402177 NCBI chr17:48,607,232...48,611,017
Ensembl chr17:48,607,232...48,633,572
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
JBrowse link
G HTRA1 HtrA serine peptidase 1 exacerbates
ameliorates
IEP
IMP
mRNA,protein:decreased expression:epithelium of esophagus (human)
human gene and cells in mouse model
RGD PMID:23079781 PMID:23079781 RGD:152975633, RGD:152975633 NCBI chr10:122,461,553...122,514,907
Ensembl chr10:122,458,551...122,514,907
JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 severity IMP human cells in mouse model RGD PMID:32367071 RGD:149735568 NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,477
JBrowse link
G JAK2 Janus kinase 2 severity IEP protein:increased phosphorylation:esophagus squamous epithelium (human) RGD PMID:32158193 RGD:127285669 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948
JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit exacerbates IEP protein:increased expression:esophagus (human) RGD PMID:30227324 PMID:19758438 RGD:151347669, RGD:151347672 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315
JBrowse link
G KAT2B lysine acetyltransferase 2B IEP mRNA:decreased expression:esophagus (human) RGD PMID:19525977 RGD:9590307 NCBI chr 3:20,040,446...20,154,404
Ensembl chr 3:20,040,446...20,154,404
JBrowse link
G KDM4C lysine demethylase 4C severity
susceptibility
IEP
IAGP
protein:increased expression:esophageal epithelium, nucleus (human)
DNA:snp:intron:IVS8-3292G>A (rs1340513) (human)
RGD PMID:24224128 PMID:15805246 RGD:9587746, RGD:9587752 NCBI chr 9:6,720,863...7,175,648
Ensembl chr 9:6,757,641...7,175,648
JBrowse link
G KDM5B lysine demethylase 5B severity IEP protein:increased expression:esophageal mucosa, cytoplasm (human) RGD PMID:22534467 RGD:9587776 NCBI chr 1:202,724,495...202,808,421
Ensembl chr 1:202,724,495...202,808,487
JBrowse link
G KDM6A lysine demethylase 6A ameliorates IAGP
IEP
EXP
DNA:mutations:multiple (human)
mRNA:increased expression:esophagus (human)
protein:increased expression:esophagus (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:25151357 PMID:25151357 PMID:31804468 PMID:29351209 RGD:9588233, RGD:150429742, RGD:150429739 NCBI chr  X:44,873,188...45,112,779
Ensembl chr  X:44,873,188...45,112,779
JBrowse link
G KMT2C lysine methyltransferase 2C IAGP
EXP
DNA:mutations:multiple (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:25151357 PMID:25151357 RGD:9588233 NCBI chr 7:152,134,925...152,436,003
Ensembl chr 7:152,134,922...152,436,644
JBrowse link
G KMT2D lysine methyltransferase 2D IAGP
IEP
EXP
DNA:mutations:multiple (human)
mRNA:increased expression:esophagus
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:25151357 PMID:25151357 PMID:29532228 RGD:9588233, RGD:150521712 NCBI chr12:49,018,978...49,060,794
Ensembl chr12:49,018,975...49,060,794
JBrowse link
G KRT13 keratin 13 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr17:41,500,981...41,505,612
Ensembl chr17:41,500,981...41,505,705
JBrowse link
G KRT14 keratin 14 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16543248 NCBI chr17:41,582,279...41,586,895
Ensembl chr17:41,582,279...41,586,895
JBrowse link
G KRT16 keratin 16 ISO RGD PMID:8950218 RGD:633113 NCBI chr17:41,609,778...41,612,767
Ensembl chr17:41,609,778...41,615,899
JBrowse link
G KRT17 keratin 17 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr17:41,619,442...41,624,575
Ensembl chr17:41,619,442...41,624,842
JBrowse link
G KRT19 keratin 19 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr17:41,523,617...41,528,308
Ensembl chr17:41,523,617...41,528,308
JBrowse link
G KRT7 keratin 7 disease_progression IEP RGD PMID:29788741 RGD:151665759 NCBI chr12:52,233,243...52,255,853
Ensembl chr12:52,232,520...52,252,186
JBrowse link
G LOC126806658 BRD4-independent group 4 enhancer GRCh37_chr3:41265899-41267098 IAGP ClinVar Annotator: match by term: Esophageal squamous cell carcinoma ClinVar PMID:25157968 PMID:25741868 PMID:26619011 NCBI chr 3:41,224,408...41,225,607 JBrowse link
G LOXL2 lysyl oxidase like 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24716982 NCBI chr 8:23,296,897...23,404,120
Ensembl chr 8:23,296,897...23,425,328
JBrowse link
G LTA lymphotoxin alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chr 6:31,560,610...31,574,324
Ensembl chr 6:31,572,054...31,574,324
JBrowse link
G LZTS1 leucine zipper tumor suppressor 1 IAGP ClinVar Annotator: match by term: Esophageal squamous cell carcinoma, somatic
ClinVar Annotator: match by term: LZTS1-related condition
OMIM
ClinVar
PMID:10097140 PMID:25741868 PMID:26504261 PMID:28492532 NCBI chr 8:20,246,165...20,303,963
Ensembl chr 8:20,246,165...20,303,963
JBrowse link
G MAD2L1 mitotic arrest deficient 2 like 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18691855 NCBI chr 4:120,055,623...120,066,848
Ensembl chr 4:120,055,623...120,066,858
JBrowse link
G MALAT1 metastasis associated lung adenocarcinoma transcript 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25538231 NCBI chr11:65,497,738...65,506,516
Ensembl chr11:65,497,640...65,508,073
JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 sexual_dimorphism IAGP DNA:missense mutation, SNP:CDS, exon 14, 3'-UTR: (rs702689,rs702688) (human) RGD PMID:32753933 RGD:150573717 NCBI chr 5:56,815,549...56,896,152
Ensembl chr 5:56,815,549...56,896,152
JBrowse link
G MBD4 methyl-CpG binding domain 4, DNA glycosylase susceptibility IAGP DNA:snp:cds:p.E346K (rs140693) (human)
DNA:snp:intron:IVS5-140A>G (rs3138355) (human)
RGD PMID:15205355 PMID:25162968 RGD:9588976, RGD:9588980 NCBI chr 3:129,430,947...129,439,948
Ensembl chr 3:129,430,947...129,440,179
JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase disease_progression EXP
IDA
CTD Direct Evidence: marker/mechanism
DNA, protein:hypermethylation, decreased expression:promoter, esophagus
CTD
RGD
PMID:25520135 PMID:21674174 RGD:126790574 NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983
JBrowse link
G MIR10A microRNA 10a IEP miRNA:increased expression:esophagus squamous epithelium (human) RGD PMID:32997362 RGD:153323343 NCBI chr17:48,579,838...48,579,947
Ensembl chr17:48,579,838...48,579,947
JBrowse link
G MIR127 microRNA 127 IEP RNA:decreased expression:esophagus (human) RGD PMID:27645894 RGD:152995354 NCBI chr14:100,882,979...100,883,075
Ensembl chr14:100,882,979...100,883,075
JBrowse link
G MIR193A microRNA 193a exacerbates IEP miRNA:decreased expression:esophagus (human) RGD PMID:27203740 RGD:153323341 NCBI chr17:31,559,996...31,560,083
Ensembl chr17:31,559,996...31,560,083
JBrowse link
G MIR217 microRNA 217 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25538231 NCBI chr 2:55,982,967...55,983,076
Ensembl chr 2:55,982,967...55,983,076
JBrowse link
G MIR31 microRNA 31 ameliorates ISO
IEP
RGD PMID:32123074 PMID:21658006 RGD:127285381, RGD:152998938 NCBI chr 9:21,512,115...21,512,185
Ensembl chr 9:21,512,115...21,512,185
JBrowse link
G MIR31HG MIR31 host gene disease_progression IEP RNA:increased expression:blood plasma, esophagus squamous epithelium (human) RGD PMID:29605445 RGD:153297774 NCBI chr 9:21,454,268...21,559,798
Ensembl chr 9:21,380,073...21,559,891
JBrowse link
G MIR423 microRNA 423 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24205249 NCBI chr17:30,117,079...30,117,172
Ensembl chr17:30,117,079...30,117,172
JBrowse link
G MIR432 microRNA 432 IEP mRNA:increased expression:esophagus (human) RGD PMID:28760781 RGD:153002560 NCBI chr14:100,884,483...100,884,576
Ensembl chr14:100,884,483...100,884,576
JBrowse link
G MIR4458 microRNA 4458 IEP RNA:decreased expression:esophagus squamous epithelium (human) RGD PMID:32449803 RGD:153345544 NCBI chr 5:8,460,925...8,460,999
Ensembl chr 5:8,460,925...8,460,999
JBrowse link
G MIR494 microRNA 494 IEP mRNA:decreased expression:esophagus RGD PMID:25480402 RGD:150530497 NCBI chr14:101,029,634...101,029,714
Ensembl chr14:101,029,634...101,029,714
JBrowse link
G MLH1 mutL homolog 1 disease_progression IDA DNA, protein:hypermethylation, decreased expression:promoter, esophagus RGD PMID:21674174 RGD:126790574 NCBI chr 3:36,993,466...37,050,846
Ensembl chr 3:36,993,226...37,050,896
JBrowse link
G MMP14 matrix metallopeptidase 14 IEP protein:increased expression: esophagus RGD PMID:24789592 RGD:152600903 NCBI chr14:22,836,585...22,847,758
Ensembl chr14:22,836,560...22,849,041
JBrowse link
G MMP2 matrix metallopeptidase 2 IEP protein:increased activity: esophagus RGD PMID:24789592 RGD:152600903 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G MMP9 matrix metallopeptidase 9 IEP protein:increased activity: esophagus RGD PMID:24789592 RGD:152600903 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G MSH2 mutS homolog 2 disease_progression IDA DNA, protein:hypermethylation, decreased expression:promoter, esophagus
DNA, protein:hypermethylation, decreased expression:esophagus
RGD PMID:22265839 PMID:21674174 PMID:24366688 RGD:126790560, RGD:126790574, RGD:126790573 NCBI chr 2:47,403,067...47,709,830
Ensembl chr 2:47,403,067...47,663,146
JBrowse link
G MT1X metallothionein 1X ISO CTD Direct Evidence: marker/mechanism CTD PMID:16543248 NCBI chr16:56,682,470...56,684,196
Ensembl chr16:56,682,470...56,684,196
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
JBrowse link
G NOTCH1 notch receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048
JBrowse link
G NOTCH2 notch receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 1:119,911,553...120,069,662
Ensembl chr 1:119,911,553...120,100,779
JBrowse link
G NOTCH3 notch receptor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr19:15,159,038...15,200,995
Ensembl chr19:15,159,038...15,200,995
JBrowse link
G PAGR1 PAXIP1 associated glutamate rich protein 1 IEP mRNA, protein:decreased expression:esophagus (human) RGD PMID:33833989 RGD:153344568 NCBI chr16:29,816,152...29,822,489
Ensembl chr16:29,816,152...29,822,489
JBrowse link
G PBX3 PBX homeobox 3 IEP RNA:increased expression:esophagus squamous epithelium (human) RGD PMID:32449803 RGD:153345544 NCBI chr 9:125,747,373...125,967,377
Ensembl chr 9:125,747,345...125,967,377
JBrowse link
G PFN1 profilin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr17:4,945,652...4,948,530
Ensembl chr17:4,945,652...4,949,061
JBrowse link
G PLCE1 phospholipase C epsilon 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20729852 PMID:20729853 NCBI chr10:93,993,931...94,332,823
Ensembl chr10:93,993,931...94,332,823
JBrowse link
G PRDX1 peroxiredoxin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,510,914...45,542,732
JBrowse link
G PSMB9 proteasome 20S subunit beta 9 disease_progression IEP RGD PMID:19492245 RGD:6482249 NCBI chr 6:32,854,192...32,859,851
Ensembl chr 6:32,844,136...32,859,851
JBrowse link
G PSME1 proteasome activator subunit 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr14:24,136,194...24,138,962
Ensembl chr14:24,136,163...24,138,967
JBrowse link
G PSME2 proteasome activator subunit 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr14:24,143,365...24,146,610
Ensembl chr14:24,143,362...24,147,570
JBrowse link
G PTCH1 patched 1 disease_progression IEP RGD PMID:16475698 RGD:150523841 NCBI chr 9:95,442,980...95,516,971
Ensembl chr 9:95,442,980...95,517,057
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15756444 PMID:16543248 PMID:18197933 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G PTPRT protein tyrosine phosphatase receptor type T susceptibility IAGP DNA:SNPs:3'utr: (rs2866943 , rs6029959 ) (human) RGD PMID:25967969 RGD:150520191 NCBI chr20:42,031,890...43,189,906
Ensembl chr20:42,072,752...43,189,970
JBrowse link
G RB1 RB transcriptional corepressor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436
JBrowse link
G RICTOR RPTOR independent companion of MTOR complex 2 disease_progression
severity
IMP
IEP
human cells in mouse model
protein:increased expression:esophagus (human)
RGD PMID:30119206 PMID:32642408 PMID:28132115 RGD:152995460, RGD:152995512, RGD:152995470 NCBI chr 5:38,937,920...39,074,399
Ensembl chr 5:38,937,920...39,074,402
JBrowse link
G RNF6 ring finger protein 6 IAGP ClinVar Annotator: match by term: Esophageal squamous cell carcinoma, somatic OMIM
ClinVar
PMID:12154016 NCBI chr13:26,132,115...26,223,085
Ensembl chr13:26,132,115...26,222,314
JBrowse link
G RUNX1 RUNX family transcription factor 1 IAGP DNA:SNP: :rs2014300 (human) RGD PMID:30666517 RGD:126775149 NCBI chr21:34,787,801...35,049,302
Ensembl chr21:34,787,801...36,004,667
JBrowse link
G RUNX2 RUNX family transcription factor 2 IEP mRNA:increased expression:esophagus mucosa RGD PMID:18500170 RGD:126779568 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349
JBrowse link
G RUNX3 RUNX family transcription factor 3 disease_progression IEP mRNA:decreased expression:esophagus mucosa RGD PMID:18500170 RGD:126779568 NCBI chr 1:24,899,511...24,965,138
Ensembl chr 1:24,899,511...24,965,121
JBrowse link
G SALL4 spalt like transcription factor 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30431698 NCBI chr20:51,782,331...51,802,521
Ensembl chr20:51,782,331...51,802,521
JBrowse link
G SERPINB3 serpin family B member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr18:63,655,197...63,661,893
Ensembl chr18:63,655,197...63,661,893
JBrowse link
G SETD5 SET domain containing 5 disease_progression IEP RGD PMID:31981592 RGD:155804254 NCBI chr 3:9,397,615...9,478,154
Ensembl chr 3:9,397,615...9,479,240
JBrowse link
G SFN stratifin EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 1:26,863,149...26,864,456
Ensembl chr 1:26,863,149...26,864,456
JBrowse link
G SLC16A10 solute carrier family 16 member 10 IEP protein:increased expression:esophagus RGD PMID:33609949 RGD:151361149 NCBI chr 6:111,087,503...111,231,194
Ensembl chr 6:111,087,503...111,231,194
JBrowse link
G SLC1A5 solute carrier family 1 member 5 disease_progression IEP protein:increased expression:esophagus RGD PMID:33609949 PMID:26936531 RGD:151361149, RGD:11532833 NCBI chr19:46,774,883...46,788,594
Ensembl chr19:46,774,883...46,788,594
JBrowse link
G SLC39A6 solute carrier family 39 member 6 EXP CTD Direct Evidence: therapeutic CTD PMID:23644492 NCBI chr18:36,108,531...36,129,340
Ensembl chr18:36,108,531...36,129,385
JBrowse link
G SLC52A3 solute carrier family 52 member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20729853 NCBI chr20:760,080...780,033
Ensembl chr20:760,080...776,015
JBrowse link
G SLC7A5 solute carrier family 7 member 5 disease_progression IEP protein:increased expression:esophagus RGD PMID:31726270 PMID:26936531 PMID:33609949 RGD:151361144, RGD:11532833, RGD:151361149 NCBI chr16:87,830,023...87,869,507
Ensembl chr16:87,830,023...87,869,507
JBrowse link
G SOCS1 suppressor of cytokine signaling 1 severity
treatment
IEP
ISO
mRNA:decreased expression:esophagus RGD PMID:21385099 PMID:31728180 PMID:28233302 RGD:150573691, RGD:150573815, RGD:150573812 NCBI chr16:11,254,417...11,256,204
Ensembl chr16:11,254,417...11,256,204
JBrowse link
G SOD2 superoxide dismutase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18167182 PMID:21517111 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SOX2 SRY-box transcription factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19801978 NCBI chr 3:181,711,925...181,714,436
Ensembl chr 3:181,711,925...181,714,436
JBrowse link
G SPEN spen family transcriptional repressor IAGP associated with Neoplasm Metastasis; DNA:mutations RGD PMID:33363385 RGD:151347445 NCBI chr 1:15,847,707...15,940,456
Ensembl chr 1:15,836,095...15,940,456
JBrowse link
G STIM1 stromal interaction molecule 1 exacerbates HEP protein:increased expression:esophagus (human) RGD PMID:31843504 RGD:152995393 NCBI chr11:3,854,604...4,093,210
Ensembl chr11:3,854,527...4,093,210
JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25129146 NCBI chr 5:139,475,533...139,482,758
Ensembl chr 5:139,475,533...139,482,935
JBrowse link
G SULT1A1 sulfotransferase family 1A member 1 IAGP DNA:SNP:exon:p.R213H, 638G>A (human) RGD PMID:12455060 RGD:1581448 NCBI chr16:28,605,258...28,623,375
Ensembl chr16:28,605,196...28,610,044
JBrowse link
G TAGLN transgelin EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr11:117,199,294...117,207,465
Ensembl chr11:117,199,370...117,207,464
JBrowse link
G TAP1 transporter 1, ATP binding cassette subfamily B member IEP protein:decreased expression:esophagus RGD PMID:19492245 RGD:6482249 NCBI chr 6:32,845,209...32,853,704
Ensembl chr 6:32,845,209...32,853,816
JBrowse link
G TAP2 transporter 2, ATP binding cassette subfamily B member IEP protein:decreased expression:esophagus RGD PMID:19492245 RGD:6482249 NCBI chr 6:32,821,831...32,838,739
Ensembl chr 6:32,821,833...32,838,739
JBrowse link
G TCN2 transcobalamin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chr22:30,607,174...30,627,271
Ensembl chr22:30,607,003...30,627,271
JBrowse link
G TERT telomerase reverse transcriptase susceptibility
no_association
IAGP
IEP
DNA:SNPs: : rs2853691,rs2736100(human)
mRNA:increased expression:esophagus squamous epithelium:
DNA:SNP: :rs2736098(human)
RGD PMID:26716642 PMID:15112252 PMID:25007268 RGD:11572962, RGD:152977757, RGD:150530488 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068
JBrowse link
G TET2 tet methylcytosine dioxygenase 2 severity IEP
IAGP
mRNA:decreased expression:esophagus squamous epithelium (human)
associated with Lymphatic Metastasis;mRNA:decreased expression:esophagus squamous epithelium (human)
DNA:mutations
RGD PMID:26093090 PMID:27050164 PMID:26873401 RGD:11528815, RGD:150429668, RGD:150429656 NCBI chr 4:105,145,875...105,279,803
Ensembl chr 4:105,145,875...105,279,816
JBrowse link
G TET3 tet methylcytosine dioxygenase 3 IEP mRNA:decreased expression:esophagus squamous epithelium (human) RGD PMID:27050164 RGD:150429668 NCBI chr 2:73,983,631...74,135,498
Ensembl chr 2:73,984,910...74,108,176
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 IAGP OMIM NCBI chr 3:30,606,356...30,694,142
Ensembl chr 3:30,606,601...30,694,142
JBrowse link
G TNFAIP3 TNF alpha induced protein 3 severity IEP mRNA,protein:increased expression:esophagus squamous epithelium (human) RGD PMID:28197630 RGD:151347617 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314
JBrowse link
G TNFAIP8 TNF alpha induced protein 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21969086 NCBI chr 5:119,268,759...119,399,688
Ensembl chr 5:119,268,692...119,399,688
JBrowse link
G TNXB tenascin XB EXP CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chr 6:32,041,153...32,109,338
Ensembl chr 6:32,041,153...32,115,334
JBrowse link
G TP53 tumor protein p53 IAGP
EXP
ISO
DNA:misssense mutation: :p.R72P (rs1042522) (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16543248 PMID:25151357 PMID:28789369 RGD:14995932 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TPI1 triosephosphate isomerase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr12:6,867,420...6,870,948
Ensembl chr12:6,867,119...6,870,948
JBrowse link
G TPM1 tropomyosin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr15:63,042,747...63,071,915
Ensembl chr15:63,042,620...63,071,915
JBrowse link
G TPM2 tropomyosin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 9:35,681,993...35,690,056
Ensembl chr 9:35,681,992...35,690,056
JBrowse link
G TXNDC17 thioredoxin domain containing 17 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr17:6,641,060...6,644,541
Ensembl chr17:6,640,985...6,644,541
JBrowse link
G TYMP thymidine phosphorylase EXP CTD Direct Evidence: marker/mechanism CTD PMID:11641616 NCBI chr22:50,525,752...50,530,085
Ensembl chr22:50,525,752...50,530,032
JBrowse link
G USP8 ubiquitin specific peptidase 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:35022897 NCBI chr15:50,424,405...50,514,421
Ensembl chr15:50,424,380...50,514,421
JBrowse link
G VENTX VENT homeobox EXP CTD Direct Evidence: marker/mechanism CTD PMID:30431698 NCBI chr10:133,237,855...133,241,928
Ensembl chr10:133,237,855...133,241,928
JBrowse link
G WRAP53 WD repeat containing antisense to TP53 disease_progression IEP RGD PMID:24626331 RGD:21081532 NCBI chr17:7,686,071...7,703,502
Ensembl chr17:7,686,071...7,703,502
JBrowse link
G WWOX WW domain containing oxidoreductase IAGP
EXP
esophageal squamous cell carcinoma, OMIM:133239
ClinVar Annotator: match by term: Esophageal squamous cell carcinoma, somatic
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
RGD
PMID:11956080 PMID:25526675 PMID:28492532 PMID:11956080 RGD:1599874 NCBI chr16:78,099,654...79,212,667
Ensembl chr16:78,099,400...79,212,667
JBrowse link
G XPO1 exportin 1 exacerbates IEP mRNA, protein:increased expression:epithelium of esophagus (human)
protein:increased expression:esophagus (human)
RGD PMID:24898882 PMID:25148895 RGD:151667431, RGD:151667436 NCBI chr 2:61,477,849...61,538,612
Ensembl chr 2:61,476,032...61,538,741
JBrowse link
G XRCC1 X-ray repair cross complementing 1 no_association
susceptibility
treatment
EXP
IAGP
CTD Direct Evidence: marker/mechanism
DNA:missense mutation:cds: p.R399Q (human)
DNA:SNPs,haplotypes:multiple (human)
DNA:SNPs:exon 6, exon 9, exon 10:multiple (human)
CTD
RGD
PMID:16639733 PMID:11400117 PMID:25710005 PMID:27123143 PMID:28356949 RGD:151347444, RGD:150530501, RGD:150530634, RGD:150530505 NCBI chr19:43,543,311...43,575,527
Ensembl chr19:43,543,311...43,580,473
JBrowse link
G ZCCHC12 zinc finger CCHC-type containing 12 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30431698 NCBI chr  X:118,823,824...118,826,968
Ensembl chr  X:118,823,824...118,826,968
JBrowse link
Familial Cystic Parathyroid Adenomatosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC73 cell division cycle 73 IAGP ClinVar Annotator: match by term: Cystic parathyroid adenoma ClinVar PMID:12434154 NCBI chr 1:193,122,031...193,254,815
Ensembl chr 1:193,121,983...193,254,815
JBrowse link
familial medullary thyroid carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INSRR insulin receptor related receptor IAGP ClinVar Annotator: match by term: Familial medullary thyroid carcinoma | ClinVar Annotator: match by term: Thyroid cancer, familial medullary ClinVar NCBI chr 1:156,840,063...156,859,117
Ensembl chr 1:156,840,063...156,859,117
JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 IAGP ClinVar Annotator: match by term: Thyroid cancer, familial medullary
ClinVar Annotator: match by term: Familial medullary thyroid carcinoma | ClinVar Annotator: match by term: Thyroid cancer, familial medullary
ClinVar PMID:10330344 PMID:10443680 PMID:10861667 PMID:11139246 PMID:11159935 More... NCBI chr 1:156,815,750...156,881,850
Ensembl chr 1:156,815,636...156,881,850
JBrowse link
G PRLR prolactin receptor ISS OMIM:155240 MouseDO NCBI chr 5:35,048,756...35,230,487
Ensembl chr 5:35,048,756...35,230,487
JBrowse link
G RET ret proto-oncogene IAGP
EXP
ClinVar Annotator: match by term: Familial medullary thyroid carcinoma
ClinVar Annotator: match by term: Familial medullary thyroid carcinoma | ClinVar Annotator: match by term: Thyroid cancer, familial medullary
CTD Direct Evidence: marker/mechanism
ClinVar
OMIM
CTD
PMID:2660074 PMID:3078962 PMID:3697657 PMID:7536460 PMID:7595170 More... NCBI chr10:43,077,069...43,130,351
Ensembl chr10:43,077,064...43,130,351
JBrowse link
Follicular Thyroid Cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRAF B-Raf proto-oncogene, serine/threonine kinase IAGP ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2 ClinVar PMID:12068308 PMID:12198537 PMID:12960123 PMID:14679157 PMID:15035987 More... NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929
JBrowse link
G CBX7 chromobox 7 IEP protein:decreased expression:thyroid gland: RGD PMID:18701502 RGD:9587357 NCBI chr22:39,130,772...39,152,680
Ensembl chr22:39,120,167...39,152,680
JBrowse link
G CGA glycoprotein hormones, alpha polypeptide EXP CTD Direct Evidence: marker/mechanism CTD PMID:10566621 NCBI chr 6:87,085,498...87,095,106
Ensembl chr 6:87,085,498...87,095,106
JBrowse link
G HRAS HRas proto-oncogene, GTPase IAGP
EXP
ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2
ClinVar Annotator: match by term: THYROID CANCER, NONMEDULLARY, 2
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:12727991 PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 More... NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321
JBrowse link
G LRRC56 leucine rich repeat containing 56 IAGP ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2
ClinVar Annotator: match by term: THYROID CANCER, NONMEDULLARY, 2
ClinVar PMID:12727991 PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 More... NCBI chr11:506,462...554,912
Ensembl chr11:537,527...554,912
JBrowse link
G MINPP1 multiple inositol-polyphosphate phosphatase 1 IAGP
EXP
ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:11297621 NCBI chr10:87,504,893...87,553,461
Ensembl chr10:87,504,875...87,553,461
JBrowse link
G NRAS NRAS proto-oncogene, GTPase IAGP
EXP
ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More... NCBI chr 1:114,704,469...114,716,771
Ensembl chr 1:114,704,469...114,716,771
JBrowse link
G PAX8 paired box 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15785241 NCBI chr 2:113,215,997...113,278,921
Ensembl chr 2:113,215,997...113,278,921
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma EXP CTD Direct Evidence: marker/mechanism CTD PMID:15785241 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G PTEN phosphatase and tensin homolog IAGP ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2 ClinVar NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930
JBrowse link
G SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 IAGP
EXP
ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:23539728 PMID:25741868 PMID:28492532 NCBI chr12:63,844,700...64,162,217
Ensembl chr12:63,843,761...64,162,217
JBrowse link
glottis squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WRAP53 WD repeat containing antisense to TP53 disease_progression IEP RGD PMID:28849066 RGD:21081521 NCBI chr17:7,686,071...7,703,502
Ensembl chr17:7,686,071...7,703,502
JBrowse link
head and neck cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCNG1 cyclin G1 IEP mRNA:decreased expression:head and neck (human) RGD PMID:27982046 RGD:151361200 NCBI chr 5:163,437,571...163,457,640
Ensembl chr 5:163,437,569...163,446,151
JBrowse link
G CCNG2 cyclin G2 IEP mRNA:decreased expression:head and neck (human) RGD PMID:27982046 RGD:151361200 NCBI chr 4:77,157,207...77,170,060
Ensembl chr 4:77,157,207...77,433,388
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 exacerbates HEP mRNA:increased expression:head, neck (human) RGD PMID:31452775 RGD:150520018 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 IDA
IAGP
DNA:hypermethylation RGD PMID:20846153 PMID:16721740 RGD:14700957, RGD:14700978 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G DCDC1 doublecortin domain containing 1 IAGP ClinVar Annotator: match by term: Head and neck cancer ClinVar PMID:28492532 PMID:32266149 NCBI chr11:30,863,603...31,369,739
Ensembl chr11:30,830,369...31,369,810
JBrowse link
G EGFR epidermal growth factor receptor IAGP ClinVar Annotator: match by term: Head and neck neoplasm ClinVar PMID:18089823 PMID:18355544 PMID:21172876 PMID:21274259 PMID:23380224 More... NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 IAGP ClinVar Annotator: match by term: Head and neck neoplasm ClinVar PMID:7668257 PMID:7719344 PMID:8651276 PMID:9677057 PMID:9700203 More... NCBI chr10:121,478,330...121,598,458
Ensembl chr10:121,478,332...121,598,458
JBrowse link
G GSTM1 glutathione S-transferase mu 1 IDA
IAGP
DNA:hypermethylation RGD PMID:20846153 PMID:21133595 PMID:16721740 RGD:14700957, RGD:14700998, RGD:14700978 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTT1 glutathione S-transferase theta 1 IAGP RGD PMID:21133595 RGD:14700998
G KDM4C lysine demethylase 4C susceptibility IAGP DNA:snps:cds, intron:p.N396D (rs2296067), IVS10G>T (rs818912) (human) RGD PMID:19339270 RGD:9587748 NCBI chr 9:6,720,863...7,175,648
Ensembl chr 9:6,757,641...7,175,648
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha IAGP ClinVar Annotator: match by term: Head and neck neoplasm ClinVar PMID:15016963 PMID:15254419 PMID:15647370 PMID:15805248 PMID:16906227 More... NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093
JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein IAGP ClinVar Annotator: match by term: Head and neck cancer ClinVar PMID:32266149 NCBI chr17:5,208,920...5,234,860
Ensembl chr17:5,208,920...5,234,860
JBrowse link
G TP53 tumor protein p53 IAGP ClinVar Annotator: match by term: Head and neck neoplasm ClinVar PMID:9067756 PMID:11370630 PMID:11782540 PMID:16818505 PMID:17606709 More... NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G ZNF594-DT ZNF594 divergent transcript IAGP ClinVar Annotator: match by term: Head and neck cancer ClinVar PMID:32266149 NCBI chr17:5,192,007...5,236,003
Ensembl chr17:5,192,007...5,248,182
JBrowse link
head and neck squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25275603 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) EXP CTD Direct Evidence: marker/mechanism CTD PMID:25275603 NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257
JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25275603 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594
JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) EXP CTD Direct Evidence: marker/mechanism CTD PMID:25275603 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628
JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase IAGP ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:11569495 PMID:11853795 PMID:12399961 PMID:12623848 PMID:14745431 More... NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,043...130,887,675
JBrowse link
G AKT1 AKT serine/threonine kinase 1 EXP
IAGP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Head and neck squamous cell carcinoma
CTD
ClinVar
PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 More... NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G ANKRD17 ankyrin repeat domain 17 IAGP ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:28580594 NCBI chr 4:73,073,376...73,258,798
Ensembl chr 4:73,073,376...73,258,798
JBrowse link
G ATP7B ATPase copper transporting beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:12509969 NCBI chr13:51,932,669...52,012,132
Ensembl chr13:51,930,436...52,012,125
JBrowse link
G B2M beta-2-microglobulin IAGP ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:26619011 NCBI chr15:44,711,517...44,718,145
Ensembl chr15:44,711,358...44,718,851
JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 exacerbates HEP mRNA:increased expression:head or neck skin (human) RGD