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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Head and Neck Neoplasms
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Accession:DOID:9006169 term browser browse the term
Definition:Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)
Synonyms:exact_synonym: Head Neoplasms;   Head, Neck Neoplasms;   Neck Neoplasms;   UADT Neoplasm;   UADT Neoplasms;   Upper Aerodigestive Tract Neoplasms;   upper aerodigestive tract neoplasm
 narrow_synonym: Cancer of Head;   Cancer of Neck;   Cancer of the Head;   Cancer of the Neck;   Head Cancer;   Neck Cancer
 primary_id: MESH:D006258
 alt_id: RDO:0000780
 xref: EFO:0004284;   EFO:0005950


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Head and Neck Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOBEC3B apolipoprotein B mRNA editing enzyme catalytic subunit 3B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23852168
G AREG amphiregulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:15342401 NCBI chr 7:22,979,574...22,990,179
Ensembl chr 7:22,980,249...22,990,162
JBrowse link
G BAP1 BRCA1 associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231345 NCBI chr22:13,765,510...13,774,866
Ensembl chr22:13,764,686...13,774,740
JBrowse link
G BCL2 BCL2 apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:18566236 NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895
JBrowse link
G BCL2L1 BCL2 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18566236 NCBI chr 2:36,059,024...36,118,332
Ensembl chr 2:36,058,919...36,116,470
JBrowse link
G CEBPA CCAAT enhancer binding protein alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:17510391 NCBI chr 6:28,342,506...28,345,759
Ensembl chr 6:28,343,907...28,344,977
JBrowse link
G CSF3 colony stimulating factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:7692001 NCBI chr16:66,162,814...66,166,192
Ensembl chr16:66,163,681...66,165,172
JBrowse link
G DPYD dihydropyrimidine dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19020767 NCBI chr20:35,376,738...36,215,388
Ensembl chr20:35,377,266...36,215,679
JBrowse link
G EGFR epidermal growth factor receptor ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:12942316 PMID:15342401 PMID:16467544 PMID:23917044 RGD:5131641 NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit severity ISO mRNA:increased expression: : RGD PMID:26659720 RGD:11573297 NCBI chr 6:38,804,296...38,823,229
Ensembl chr 6:38,801,423...38,823,073
JBrowse link
G FAT1 FAT atypical cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23354438 NCBI chr 7:132,475,689...132,616,151
Ensembl chr 7:132,483,032...132,616,112
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ISO ClinVar Annotator: match by term: Head and Neck Neoplasms ClinVar PMID:7668257 PMID:7719344 PMID:8651276 PMID:9677057 PMID:9700203 More... NCBI chr 9:114,234,344...114,354,736
Ensembl chr 9:114,234,250...114,354,704
JBrowse link
G GPX1 glutathione peroxidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15557674 NCBI chr22:10,754,976...10,756,617 JBrowse link
G GRP gastrin releasing peptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:15342401 NCBI chr18:20,496,201...20,508,551
Ensembl chr18:20,496,516...20,507,153
JBrowse link
G MAL mal, T cell differentiation protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19445022 NCBI chr14:66,521...92,476
Ensembl chr14:66,610...93,588
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15342401 NCBI chr19:4,246,144...4,352,648
Ensembl chr19:4,246,122...4,353,325
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15342401 NCBI chr 5:26,536,471...26,545,666
Ensembl chr 5:26,536,532...26,546,461
JBrowse link
G MMP1 matrix metallopeptidase 1 ISO DNA:insertion:promoter:g.-1607insG (human) RGD PMID:19843588 RGD:7207056 NCBI chr 1:94,167,507...94,177,357
Ensembl chr 1:94,167,219...94,176,767
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Head and Neck Neoplasms ClinVar PMID:15016963 PMID:15254419 PMID:15647370 PMID:15805248 PMID:16906227 More... NCBI chr15:10,218,034...10,304,874
Ensembl chr15:10,218,805...10,294,316
JBrowse link
G RAD51 RAD51 recombinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22613844 NCBI chr26:42,281,085...42,319,394
Ensembl chr26:42,279,608...42,318,169
JBrowse link
G RARB retinoic acid receptor beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:17549354 NCBI chr15:69,851,447...70,266,215
Ensembl chr15:70,096,117...70,264,905
JBrowse link
G SRSF2 serine and arginine rich splicing factor 2 ISO mRNA:increased expression:head and neck (human) RGD PMID:21764905 RGD:11039047 NCBI chr16:44,945,193...44,948,496
Ensembl chr16:44,945,200...44,946,438
JBrowse link
G STAT6 signal transducer and activator of transcription 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21765211 NCBI chr11:53,005,378...53,020,899
Ensembl chr11:53,006,145...53,021,203
JBrowse link
G TGFA transforming growth factor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:15342401 NCBI chr14:36,545,641...36,654,213
Ensembl chr14:36,545,875...36,648,237
JBrowse link
G TP53 tumor protein p53 ISO ClinVar Annotator: match by term: Head and Neck Neoplasms ClinVar PMID:9067756 PMID:11370630 PMID:11782540 PMID:16818505 PMID:17606709 More... NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223
JBrowse link
G TYMS thymidylate synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19020767 NCBI chr18:60,030,640...60,043,297
Ensembl chr18:60,030,658...60,041,856
JBrowse link
G UROD uroporphyrinogen decarboxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21270338 NCBI chr20:87,772,685...87,776,110
Ensembl chr20:87,772,261...87,775,978
JBrowse link
G VEGFA vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16499871 NCBI chr17:28,377,959...28,394,508 JBrowse link
G XRCC3 X-ray repair cross complementing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22613844 NCBI chr24:81,627,911...81,641,598
Ensembl chr24:81,630,099...81,641,218
JBrowse link
acoustic neuroma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARTN artemin ISO mRNA:increased expression:peripheral nerve: RGD PMID:19937367 RGD:8655552 NCBI chr20:88,869,463...88,874,036
Ensembl chr20:88,869,941...88,871,049
JBrowse link
G BDNF brain derived neurotrophic factor ISO mRNA:increased expression:peripheral nerve: RGD PMID:19937367 RGD:8655552 NCBI chr 1:37,386,825...37,451,380
Ensembl chr 1:37,449,593...37,450,336
JBrowse link
G CAV1 caveolin 1 ISO RGD PMID:20881564 RGD:8661782 NCBI chr21:85,222,724...85,258,562
Ensembl chr21:85,222,879...85,258,627
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A ISO mRNA,protein:decreased expression:myelinated nerve: RGD PMID:20600642 RGD:8661792 NCBI chr17:35,445,668...35,454,334
Ensembl chr17:35,445,223...35,454,342
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO DNA:snp:promoter:c.-1053C>T (human) RGD PMID:12540498 RGD:1358568 NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit susceptibility ISO DNA:missense mutation:cds:p.D312N (rs1799793) (human) RGD PMID:20150366 RGD:5688735 NCBI chr 6:38,804,296...38,823,229
Ensembl chr 6:38,801,423...38,823,073
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 disease_progression ISO RGD PMID:15354013 RGD:11567268 NCBI chr 8:36,426,116...36,485,683
Ensembl chr 8:36,427,110...36,485,508
JBrowse link
G GDNF glial cell derived neurotrophic factor ISO mRNA:increased expression:peripheral nerve: RGD PMID:19937367 RGD:8655552 NCBI chr 4:36,662,033...36,691,761
Ensembl chr 4:36,665,009...36,684,257
JBrowse link
G IGF1 insulin like growth factor 1 susceptibility ISO protein:increased expression:serum: RGD PMID:21788435 RGD:8548833 NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308
JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 susceptibility ISO protein:increased expression:serum: RGD PMID:21788435 RGD:8548833 NCBI chr21:12,905,309...12,914,199
Ensembl chr21:12,905,280...12,914,205
JBrowse link
G NF2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor ISO protein:decreased expression:myelinated nerve: RGD PMID:20600642 RGD:8661792 NCBI chr19:12,474,479...12,572,144
Ensembl chr19:12,474,468...12,572,250
JBrowse link
G VEGFA vascular endothelial growth factor A ISO RGD PMID:14660915 RGD:8547959 NCBI chr17:28,377,959...28,394,508 JBrowse link
adenoid cystic carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 (Colton blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr21:27,456,553...27,473,196
Ensembl chr21:27,456,259...27,470,728
JBrowse link
G ARID1A AT-rich interaction domain 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr20:105,981,549...106,066,093
Ensembl chr20:105,981,290...106,065,672
JBrowse link
G ARID2 AT-rich interaction domain 2 ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar NCBI chr11:41,933,650...42,117,495
Ensembl chr11:42,028,083...42,118,892
JBrowse link
G ARID4B AT-rich interaction domain 4B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr25:72,338,190...72,501,999
Ensembl chr25:72,337,590...72,501,988
JBrowse link
G ARID5B AT-rich interaction domain 5B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 9:69,190,100...69,382,448
Ensembl chr 9:69,190,045...69,382,069
JBrowse link
G ASPM assembly factor for spindle microtubules ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr25:32,269,518...32,334,617
Ensembl chr25:32,281,424...32,334,977
JBrowse link
G ATM ATM serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 1:99,653,208...99,786,889
Ensembl chr 1:99,653,139...99,791,520
JBrowse link
G ATR ATR serine/threonine kinase treatment ISO RGD PMID:32001675 RGD:150340693 NCBI chr15:48,048,785...48,173,120
Ensembl chr15:48,048,882...48,173,137
JBrowse link
G ATRX ATRX chromatin remodeler ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr  X:66,449,830...66,737,220
Ensembl chr  X:66,448,449...66,737,164
JBrowse link
G BAP1 BRCA1 associated protein 1 ISO ClinVar Annotator: match by term: Adenocystic carcinoma | ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar PMID:21642991 PMID:24894717 PMID:26166446 PMID:26452128 PMID:28492532 NCBI chr22:13,765,510...13,774,866
Ensembl chr22:13,764,686...13,774,740
JBrowse link
G BCL11A BCL11 transcription factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr14:46,453,102...46,553,802 JBrowse link
G BCOR BCL6 corepressor ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar NCBI chr  X:37,191,242...37,319,966
Ensembl chr  X:37,192,874...37,319,782
JBrowse link
G BCORL1 BCL6 corepressor like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr  X:105,238,616...105,314,326
Ensembl chr  X:105,240,043...105,314,553
JBrowse link
G BRCA1 BRCA1 DNA repair associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr16:63,162,827...63,243,928 JBrowse link
G BRD1 bromodomain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr19:32,261,796...32,323,528
Ensembl chr19:32,261,833...32,320,706
JBrowse link
G CCND1 cyclin D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357
JBrowse link
G CMTR2 cap methyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 5:54,428,889...54,435,770
Ensembl chr 5:54,430,197...54,432,509
JBrowse link
G CNTN6 contactin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr22:37,212,995...37,518,060
Ensembl chr22:37,343,770...37,517,626
JBrowse link
G CREBBP CREB binding protein ISO ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:21390126 PMID:21680795 PMID:21796119 PMID:22832583 PMID:23334668 More... NCBI chr 5:3,415,548...3,570,030
Ensembl chr 5:3,415,412...3,540,943
JBrowse link
G DAPK1 death associated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr12:98,118,948...98,330,435
Ensembl chr12:98,118,603...98,330,471
JBrowse link
G DTL denticleless E3 ubiquitin protein ligase homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr25:17,418,078...17,485,320
Ensembl chr25:17,418,090...17,485,164
JBrowse link
G DTX4 deltex E3 ubiquitin ligase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 1:14,354,752...14,390,630
Ensembl chr 1:14,358,001...14,390,239
JBrowse link
G EFHD1 EF-hand domain family member D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr10:118,652,927...118,704,717
Ensembl chr10:118,653,349...118,704,701
JBrowse link
G EN1 engrailed homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 Ensembl chr10:11,475,221...11,479,475 JBrowse link
G EP300 E1A binding protein p300 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr19:23,634,132...23,726,095
Ensembl chr19:23,634,571...23,724,979
JBrowse link
G ERBIN erbb2 interacting protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 4:62,123,012...62,267,832
Ensembl chr 4:62,182,705...62,268,617
JBrowse link
G ESPL1 extra spindle pole bodies like 1, separase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr11:49,374,333...49,401,801 JBrowse link
G FANCA FA complementation group A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 5:75,073,161...75,149,110
Ensembl chr 5:75,073,358...75,148,591
JBrowse link
G FAT1 FAT atypical cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 7:132,475,689...132,616,151
Ensembl chr 7:132,483,032...132,616,112
JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 ISO ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:26619011 NCBI chr 7:98,894,261...99,105,955
Ensembl chr 7:98,892,504...99,106,084
JBrowse link
G FGF16 fibroblast growth factor 16 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr  X:66,389,983...66,401,562 JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar PMID:26619011 NCBI chr 9:114,234,344...114,354,736
Ensembl chr 9:114,234,250...114,354,704
JBrowse link
G FGFR4 fibroblast growth factor receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr23:79,095,031...79,106,018
Ensembl chr23:79,097,429...79,105,456
JBrowse link
G FOXO3 forkhead box O3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr13:65,175,764...65,303,107
Ensembl chr13:65,195,376...65,301,725
JBrowse link
G FOXP2 forkhead box P2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr21:82,799,147...83,392,568
Ensembl chr21:83,129,308...83,389,483
JBrowse link
G GAS2 growth arrest specific 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 1:42,201,546...42,376,934 JBrowse link
G GINS2 GINS complex subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 5:71,088,766...71,099,845
Ensembl chr 5:71,089,564...71,099,688
JBrowse link
G GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 7:102,206,438...102,310,535
Ensembl chr 7:102,238,477...102,303,673
JBrowse link
G H1-4 H1.4 linker histone, cluster member ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr17:46,099,264...46,100,067
Ensembl chr17:46,099,330...46,099,986
JBrowse link
G HOMER3 homer scaffold protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 6:17,385,176...17,396,506
Ensembl chr 6:17,385,175...17,394,319
JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr 1:343,613...345,782
Ensembl chr 1:343,506...346,637
JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 ISO ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20946881 More... NCBI chr10:94,021,002...94,039,997
Ensembl chr10:94,020,818...94,039,975
JBrowse link
G IGFBP2 insulin like growth factor binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr10:102,469,611...102,503,229
Ensembl chr10:102,469,669...102,503,276
JBrowse link
G IL17RD interleukin 17 receptor D ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr22:18,416,143...18,489,855
Ensembl chr22:18,416,443...18,434,271
JBrowse link
G INSRR insulin receptor related receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr20:7,008,882...7,029,377
Ensembl chr20:7,010,504...7,028,557
JBrowse link
G IRX4 iroquois homeobox 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 4:1,712,382...1,723,284
Ensembl chr 4:1,718,737...1,723,403
JBrowse link
G ISYNA1 inositol-3-phosphate synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 6:16,906,724...16,910,194
Ensembl chr 6:16,905,472...16,910,030
JBrowse link
G ITGB4 integrin subunit beta 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr16:45,926,543...45,962,967 JBrowse link
G JAG1 jagged canonical Notch ligand 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 2:27,484,699...27,521,108
Ensembl chr 2:27,484,760...27,522,504
JBrowse link
G JAK3 Janus kinase 3 ISO ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:14615376 PMID:28492532 PMID:33040328 NCBI chr 6:16,301,760...16,323,343
Ensembl chr 6:16,300,525...16,322,859
JBrowse link
G JMJD1C jumonji domain containing 1C ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 9:67,913,062...68,135,555 JBrowse link
G KANSL1 KAT8 regulatory NSL complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr16:59,692,890...59,888,955
Ensembl chr16:59,747,522...59,890,061
JBrowse link
G KAT6A lysine acetyltransferase 6A ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 8:39,912,120...40,035,776
Ensembl chr 8:39,911,776...39,962,735
JBrowse link
G KDM6A lysine demethylase 6A exacerbates ISO DNA:mutations:multiple: (human)
DNA:splice-site mutation, missense mutations:splice junction, CDS:multiple: (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:23685749 PMID:31483290 RGD:150429732 RGD:150429736 NCBI chr  X:42,053,272...42,291,013
Ensembl chr  X:42,053,336...42,290,526
JBrowse link
G KDM6B lysine demethylase 6B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr16:7,221,769...7,241,230
Ensembl chr16:7,232,426...7,241,040
JBrowse link
G KMT2C lysine methyltransferase 2C disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:23685749 PMID:31483290 RGD:150429736 NCBI chr21:120,299,295...120,587,843
Ensembl chr21:120,301,188...120,587,137
JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:6695174 PMID:12460918 PMID:15696205 PMID:16361624 PMID:16618717 More... NCBI chr11:24,963,396...25,010,747
Ensembl chr11:24,973,619...25,005,191
JBrowse link
G KRT15 keratin 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr16:64,723,180...64,729,589
Ensembl chr16:64,724,364...64,729,581
JBrowse link
G KRT5 keratin 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr11:48,660,946...48,673,593
Ensembl chr11:48,660,961...48,666,830
JBrowse link
G LOC103214855 growth arrest-specific protein 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 3:91,720,871...91,762,712 JBrowse link
G LOC103219433 nuclear factor 1 B-type ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr12:65,043,819...65,487,832
Ensembl chr12:65,256,407...65,481,485
JBrowse link
G LOC103233229 cadherin-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17520682 NCBI chr 5:58,578,244...58,679,677
Ensembl chr 5:58,578,146...58,679,541
JBrowse link
G LOC103247035 glycogen phosphorylase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588
G LRRC56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr 1:352,131...370,276
Ensembl chr 1:355,982...369,633
JBrowse link
G MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr22:26,383,310...27,057,081
Ensembl chr22:26,384,511...26,645,528
JBrowse link
G MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr21:69,460,345...70,916,684 JBrowse link
G MAML3 mastermind like transcriptional coactivator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 7:86,673,649...87,107,768
Ensembl chr 7:86,673,346...86,848,086
JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 6:3,848,441...3,881,367
Ensembl chr 6:3,848,401...3,881,412
JBrowse link
G MARCKS myristoylated alanine rich protein kinase C substrate ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr13:59,989,920...59,995,921
Ensembl chr13:59,989,778...59,995,940
JBrowse link
G MARK2 microtubule affinity regulating kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 1:10,336,690...10,410,539
Ensembl chr 1:10,336,639...10,409,951
JBrowse link
G MECOM MDS1 and EVI1 complex locus ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar NCBI chr15:19,726,423...20,320,832
Ensembl chr15:20,256,384...20,320,834
JBrowse link
G MGA MAX dimerization protein MGA ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr26:41,215,424...41,381,828
Ensembl chr26:41,218,082...41,311,526
JBrowse link
G MIER2 MIER family member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 6:35,532...70,736 JBrowse link
G MLC1 modulator of VRAC current 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr19:32,559,208...32,583,522
Ensembl chr19:32,557,536...32,583,060
JBrowse link
G MORF4L1 mortality factor 4 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr26:4,500,848...4,520,830 JBrowse link
G MYB MYB proto-oncogene, transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 PMID:26829750 NCBI chr13:38,203,923...38,242,148
Ensembl chr13:38,203,731...38,241,864
JBrowse link
G MYBL1 MYB proto-oncogene like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 8:62,440,620...62,489,148
Ensembl chr 8:62,442,204...62,478,819
JBrowse link
G MYCBP MYC binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr20:94,017,529...94,027,727
Ensembl chr20:94,017,632...94,029,150
JBrowse link
G MYCN MYCN proto-oncogene, bHLH transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr14:91,685,376...91,692,091 JBrowse link
G NETO2 neuropilin and tolloid like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 5:32,929,091...32,991,240
Ensembl chr 5:32,930,692...32,979,561
JBrowse link
G NOTCH1 notch receptor 1 ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar NCBI chr12:1,656,815...1,707,566
Ensembl chr12:1,656,918...1,709,585
JBrowse link
G NSD1 nuclear receptor binding SET domain protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr23:79,140,148...79,309,579
Ensembl chr23:79,141,114...79,304,820
JBrowse link
G NTRK3 neurotrophic receptor tyrosine kinase 3 treatment ISO RGD PMID:23027130 RGD:150519921 NCBI chr29:6,441,824...6,831,029
Ensembl chr29:6,447,256...6,830,526
JBrowse link
G PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr  X:45,957,760...45,962,588
Ensembl chr  X:45,957,715...45,962,601
JBrowse link
G PDZK1 PDZ domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr20:13,026,422...13,076,094
Ensembl chr20:13,040,475...13,079,241
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:15930273 PMID:17376864 PMID:18074223 PMID:19366826 PMID:22120714 More... NCBI chr15:10,218,034...10,304,874
Ensembl chr15:10,218,805...10,294,316
JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 8:43,915,226...44,119,547
Ensembl chr 8:43,914,636...44,119,541
JBrowse link
G PTEN phosphatase and tensin homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146
JBrowse link
G RBFOX2 RNA binding fox-1 homolog 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr19:18,507,184...18,801,535 JBrowse link
G SERPINF1 serpin family F member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr16:1,408,453...1,424,197 JBrowse link
G SETD2 SET domain containing 2, histone lysine methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr22:8,421,178...8,567,221
Ensembl chr22:8,420,960...8,567,201
JBrowse link
G SF3B1 splicing factor 3b subunit 1 ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar PMID:25741868 PMID:26619011 NCBI chr10:82,901,908...82,952,094
Ensembl chr10:82,899,079...82,952,071
JBrowse link
G SLC24A3 solute carrier family 24 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 2:48,238,872...48,736,517 JBrowse link
G SLC3A2 solute carrier family 3 member 2 disease_progression ISO RGD PMID:23516127 RGD:151361211 NCBI chr 1:11,011,351...11,050,494
Ensembl chr 1:11,008,120...11,050,298
JBrowse link
G SLC7A5 solute carrier family 7 member 5 disease_progression ISO RGD PMID:23516127 RGD:151361211 NCBI chr 5:73,229,953...73,269,801
Ensembl chr 5:73,229,951...73,269,754
JBrowse link
G SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar NCBI chr12:77,364,468...77,546,356
Ensembl chr12:77,375,500...77,546,314
JBrowse link
G SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar NCBI chr19:6,902,985...6,945,111
Ensembl chr19:6,902,951...6,944,784
JBrowse link
G SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr16:65,539,138...65,559,810
Ensembl chr16:65,541,513...65,561,401
JBrowse link
G SMC1A structural maintenance of chromosomes 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr  X:49,514,652...49,558,490
Ensembl chr  X:49,515,061...49,558,447
JBrowse link
G SON SON DNA and RNA binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 2:58,610,076...58,643,758 JBrowse link
G SOX11 SRY-box transcription factor 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr14:101,982,551...101,991,305
Ensembl chr14:101,989,895...101,991,220
JBrowse link
G SRCAP Snf2 related CREBBP activator protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 5:27,386,923...27,428,360
Ensembl chr 5:27,389,572...27,427,953
JBrowse link
G ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 1:117,479,328...117,543,262
Ensembl chr 1:117,480,451...117,542,671
JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar NCBI chr16:63,877,884...63,957,894
Ensembl chr16:63,922,862...63,957,984
JBrowse link
G TLK1 tousled like kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr10:56,521,983...56,688,458
Ensembl chr10:56,523,879...56,592,671
JBrowse link
G TOP2A DNA topoisomerase II alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr16:65,761,391...65,792,041
Ensembl chr16:65,761,416...65,792,701
JBrowse link
G TP53 tumor protein p53 disease_progression ISO ClinVar Annotator: match by term: Adenocystic carcinoma | ClinVar Annotator: match by term: Adenoid cystic carcinoma RGD
ClinVar
PMID:1673792 PMID:1686725 PMID:6736287 PMID:7707106 PMID:7881428 More... RGD:8547828 NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223
JBrowse link
G UHRF1 ubiquitin like with PHD and ring finger domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 6:4,592,362...4,642,179
Ensembl chr 6:4,592,919...4,642,445
JBrowse link
G VCAN versican ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 4:77,581,627...77,692,495
Ensembl chr 4:77,593,449...77,690,616
JBrowse link
G WNT5B Wnt family member 5B ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr11:1,571,569...1,689,750
Ensembl chr11:1,674,245...1,690,299
JBrowse link
G XRN2 5'-3' exoribonuclease 2 ISO DNA:hypermethylation:3' utr: (human) RGD PMID:21692051 RGD:11041796 NCBI chr 2:50,287,718...50,373,869
Ensembl chr 2:50,288,073...50,373,883
JBrowse link
G ZIM2 zinc finger imprinted 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 6:49,249,179...49,269,826 JBrowse link
adenoid squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNF1A HNF1 homeobox A ISO RGD PMID:10489374 RGD:150540314 NCBI chr11:116,334,935...116,358,582
Ensembl chr11:116,335,675...116,357,751
JBrowse link
Barrett's adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPX3 glutathione peroxidase 3 ISO DNA:hypermethylation
DNA:hypermethylation:promoter
RGD PMID:16229808 PMID:18664505 RGD:151665354 RGD:151665749 NCBI chr23:53,576,950...53,585,321 JBrowse link
G GPX7 glutathione peroxidase 7 ISO DNA:hypermethylation:promoter RGD PMID:18664505 RGD:151665749 NCBI chr20:80,335,248...80,342,687
Ensembl chr20:80,335,033...80,342,124
JBrowse link
G LOC103216270 cytochrome P450 26A1 ISO RGD PMID:18059332 RGD:13782259 NCBI chr 9:86,310,142...86,328,622
Ensembl chr 9:86,325,401...86,328,775
JBrowse link
congenital heart defects, hamartomas of tongue, and polysyndactyly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WDPCP WD repeat containing planar cell polarity effector ISO ClinVar Annotator: match by term: Heart defect - tongue hamartoma - polysyndactyly syndrome | ClinVar Annotator: match by term: WDPCP-related condition OMIM
ClinVar
PMID:9536098 PMID:16199547 PMID:17576681 PMID:20671153 PMID:25326635 More... NCBI chr14:43,425,405...43,896,015
Ensembl chr14:43,526,525...43,898,300
JBrowse link
Cutaneous Telangiectasia and Cancer Syndrome, Familial term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATR ATR serine/threonine kinase ISO ClinVar Annotator: match by term: Cutaneous telangiectasia and cancer syndrome, familial OMIM
ClinVar
PMID:9536098 PMID:15987455 PMID:17010193 PMID:17576681 PMID:18414213 More... NCBI chr15:48,048,785...48,173,120
Ensembl chr15:48,048,882...48,173,137
JBrowse link
esophageal cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 ISO protein:increased expression:esophagus (human) RGD PMID:27188433 RGD:152995510 NCBI chr24:82,704,087...82,730,711
Ensembl chr24:82,704,068...82,727,698
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member ISO ClinVar Annotator: match by term: Esophageal cancer, alcohol-related, susceptibility to ClinVar PMID:2987944 PMID:4065146 PMID:6650498 PMID:7180842 PMID:7593603 More... NCBI chr11:107,019,015...107,060,784
Ensembl chr11:107,019,111...107,060,374
JBrowse link
G BHLHE41 basic helix-loop-helix family member e41 ISO protein:increased expression:esophagus(human) RGD PMID:29890466 RGD:151665308 NCBI chr11:25,872,139...25,879,985
Ensembl chr11:25,874,108...25,876,826
JBrowse link
G BRCA2 BRCA2 DNA repair associated ISO ClinVar Annotator: match by term: Esophagus cancer ClinVar PMID:25741868 PMID:28492532 PMID:31911673 NCBI chr 3:11,070,086...11,155,257
Ensembl chr 3:11,071,682...11,155,213
JBrowse link
G CTNNA1 catenin alpha 1 disease_progression ISO RGD PMID:9863006 RGD:2289811 NCBI chr23:41,423,504...41,599,458
Ensembl chr23:41,447,675...41,600,190
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 ISO protein:increased expression:serum RGD PMID:20232121 RGD:5134997 NCBI chr 7:22,327,041...22,329,405
Ensembl chr 7:22,569,355...22,569,900
Ensembl chr 7:22,569,355...22,569,900
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO RGD PMID:11833070 PMID:26782562 RGD:11554919 RGD:14700950 NCBI chr26:8,753,236...8,759,378
Ensembl chr26:8,753,327...8,759,384
JBrowse link
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 ameliorates ISO RNA:decreased expression:esophagus (human) RGD PMID:14760115 RGD:152025255 NCBI chr 2:9,868,794...9,889,510
Ensembl chr 2:9,868,678...9,885,884
JBrowse link
G DLEC1 DLEC1 cilia and flagella associated protein ISO ClinVar Annotator: match by term: Esophagus cancer ClinVar PMID:25741868 NCBI chr15:1,297,129...1,364,134
Ensembl chr15:1,296,204...1,363,806
JBrowse link
G FGF2 fibroblast growth factor 2 ISO RGD PMID:29660336 RGD:21409755 NCBI chr 7:70,089,394...70,157,423 JBrowse link
G GPX3 glutathione peroxidase 3 treatment ISO DNA:hypermethylation RGD PMID:33292587 RGD:151665781 NCBI chr23:53,576,950...53,585,321 JBrowse link
G HMOX1 heme oxygenase 1 ISO protein:increased expression:esophagus RGD PMID:20498946 RGD:4145286 NCBI chr19:18,144,466...18,157,944
Ensembl chr19:18,144,545...18,157,971
JBrowse link
G IL10 interleukin 10 treatment ISO RGD PMID:26603620 RGD:152998997 NCBI chr25:22,590,389...22,595,877
Ensembl chr25:22,590,962...22,594,836
JBrowse link
G IL1B interleukin 1 beta treatment ISO RGD PMID:26603620 RGD:152998997 NCBI chr14:15,844,628...15,852,652
Ensembl chr14:15,844,672...15,850,729
JBrowse link
G IL1R2 interleukin 1 receptor type 2 susceptibility ISO DNA:SNP:cds:rs11674595|rs2072472 (human) RGD PMID:31744444 RGD:152998961 NCBI chr14:5,672,434...5,708,270
Ensembl chr14:5,673,163...5,708,372
JBrowse link
G IL5 interleukin 5 treatment ISO RGD PMID:20232121 RGD:5134997 NCBI chr23:35,360,143...35,375,169
Ensembl chr23:35,360,506...35,362,178
JBrowse link
G LOC103224275 glutathione S-transferase Mu 1 ISO RGD PMID:11833070 PMID:12406553 PMID:23749488 PMID:26782562 RGD:11554919 RGD:14700950 RGD:14700964 RGD:14700969 NCBI chr20:23,854,969...23,861,634 JBrowse link
G LZTS1 leucine zipper tumor suppressor 1 ISO esophageal squamous cell carcinoma, OMIM:133239 RGD PMID:10097140 RGD:1600104 NCBI chr 8:18,315,243...18,377,492
Ensembl chr 8:18,315,130...18,324,345
JBrowse link
G MAF MAF bZIP transcription factor ISO ClinVar Annotator: match by term: Esophagus cancer ClinVar PMID:25741868 PMID:28492532 NCBI chr 5:65,064,715...65,078,972 JBrowse link
G MXI1 MAX interactor 1, dimerization protein ISO RGD PMID:10849326 RGD:1298988 NCBI chr 9:103,131,534...103,211,609
Ensembl chr 9:103,131,420...103,209,231
JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor ISO mRNA:splice variants:esophagus (human) RGD PMID:24527027 RGD:150519911 NCBI chr15:1,276,804...1,281,811
Ensembl chr15:1,276,798...1,281,166
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO protein:increased expression:esophagus (human) RGD PMID:27188433 RGD:152995510 NCBI chr15:10,218,034...10,304,874
Ensembl chr15:10,218,805...10,294,316
JBrowse link
G PTEN phosphatase and tensin homolog treatment ISO human gene and cells in a mouse model
protein:decreased expression:esophagus (human)
RGD PMID:20378992 PMID:27188433 RGD:127285592 RGD:152995510 NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146
JBrowse link
G SOCS1 suppressor of cytokine signaling 1 ISO mRNA,protein:decreased expression:esophagus: RGD PMID:33862112 RGD:151232285 NCBI chr 5:10,731,866...10,733,745
Ensembl chr 5:10,732,350...10,732,991
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO ClinVar Annotator: match by term: Esophagus cancer ClinVar PMID:7664267 PMID:9395234 PMID:9536098 PMID:10789724 PMID:11212236 More... NCBI chr15:75,112,903...75,200,263
Ensembl chr15:75,112,561...75,197,711
JBrowse link
G TNFAIP3 TNF alpha induced protein 3 disease_progression
severity
ISO DNA:SNP:intron 6: (rs610604) (human)
DNA:SNP:3'utr: (rs583522) (human)
RGD PMID:25354935 PMID:26598072 RGD:11075880 RGD:151347597 NCBI chr13:35,537,103...35,553,396
Ensembl chr13:35,537,102...35,549,197
JBrowse link
G TP53 tumor protein p53 ISO ClinVar Annotator: match by term: Esophagus cancer ClinVar PMID:7887414 PMID:8023157 PMID:8118819 PMID:8164043 PMID:8825920 More... NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223
JBrowse link
G WWOX WW domain containing oxidoreductase ISO ClinVar Annotator: match by term: Esophagus cancer ClinVar PMID:24456803 PMID:25411445 PMID:25741868 PMID:26467025 PMID:28492532 More... NCBI chr 5:63,580,049...64,698,212
Ensembl chr 5:63,580,741...63,916,157
JBrowse link
G XRCC1 X-ray repair cross complementing 1 susceptibility ISO DNA:missense mutation:exon 9: p.T304A, c.910A>G (human) RGD PMID:24345911 RGD:150530620 NCBI chr 6:37,062,149...37,095,138
Ensembl chr 6:37,060,439...37,095,094
JBrowse link
esophageal carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIRC7 baculoviral IAP repeat containing 7 disease_progression ISO mRNA:increased expression:esophagus (human) RGD PMID:31964418 RGD:153344516 NCBI chr 2:965,811...970,983 JBrowse link
G BRCA2 BRCA2 DNA repair associated ISO ClinVar Annotator: match by term: Carcinoma of esophagus ClinVar PMID:17972177 PMID:18431501 PMID:18627636 PMID:18779604 PMID:21120943 More... NCBI chr 3:11,070,086...11,155,257
Ensembl chr 3:11,071,682...11,155,213
JBrowse link
G CTNNB1 catenin beta 1 ISO ClinVar Annotator: match by term: Carcinoma of esophagus | ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:9065402 PMID:9065403 PMID:9294210 PMID:10027390 PMID:10192393 More... NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949
JBrowse link
G DCC DCC netrin 1 receptor ISO ClinVar Annotator: match by term: Esophageal carcinoma, somatic ClinVar PMID:8187090 NCBI chr18:27,437,224...28,623,717
Ensembl chr18:27,442,489...28,212,697
JBrowse link
G EGFR epidermal growth factor receptor ISO ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:15623594 PMID:16205628 PMID:16707764 PMID:16863509 PMID:17653080 More... NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239
JBrowse link
G EP300 E1A binding protein p300 ISO ClinVar Annotator: match by term: Carcinoma of esophagus ClinVar PMID:26619011 NCBI chr19:23,634,132...23,726,095
Ensembl chr19:23,634,571...23,724,979
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: Carcinoma of esophagus ClinVar PMID:16397024 PMID:23220880 PMID:25157968 PMID:26619011 NCBI chr16:66,435,488...66,464,993
Ensembl chr16:66,434,251...66,464,952
JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 ISO ClinVar Annotator: match by term: Carcinoma of esophagus | ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:25741868 PMID:26619011 NCBI chr 7:98,894,261...99,105,955
Ensembl chr 7:98,892,504...99,106,084
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ISO ClinVar Annotator: match by term: Carcinoma of esophagus | ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:25157968 PMID:26619011 NCBI chr 9:114,234,344...114,354,736
Ensembl chr 9:114,234,250...114,354,704
JBrowse link
G GRB7 growth factor receptor bound protein 7 exacerbates ISO mRNA:increased expression:esophagus mucosa (human) RGD PMID:8988034 RGD:151347660 NCBI chr16:66,416,978...66,427,035
Ensembl chr16:66,416,904...66,426,300
JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Carcinoma of esophagus | ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr 1:343,613...345,782
Ensembl chr 1:343,506...346,637
JBrowse link
G HTRA1 HtrA serine peptidase 1 disease_progression ISO mRNA,protein:decreased expression:esophagus (human) RGD PMID:22935172 RGD:152985525 NCBI chr 9:115,197,543...115,250,092
Ensembl chr 9:115,197,566...115,253,919
JBrowse link
G JAK2 Janus kinase 2 treatment ISO associated with Immune Deficiency Disease, human cells in mouse model RGD PMID:25724470 RGD:127285656 NCBI chr12:74,421,243...74,566,766
Ensembl chr12:74,421,016...74,566,710
JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:16361624 PMID:16618717 PMID:18316791 PMID:19114683 PMID:19679400 More... NCBI chr11:24,963,396...25,010,747
Ensembl chr11:24,973,619...25,005,191
JBrowse link
G LRRC56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Carcinoma of esophagus | ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr 1:352,131...370,276
Ensembl chr 1:355,982...369,633
JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 exacerbates ISO mRNA:decreased expression:espohagus (human) RGD PMID:32831056 RGD:155630592 NCBI chr 6:7,355,387...7,365,944
Ensembl chr 6:7,355,434...7,364,398
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO ClinVar Annotator: match by term: Carcinoma of esophagus ClinVar PMID:25157968 PMID:26619011 NCBI chr 8:122,282,989...122,288,392
Ensembl chr 8:122,282,630...122,288,384
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Esophageal carcinoma
ClinVar Annotator: match by term: Carcinoma of esophagus | ClinVar Annotator: match by term: Esophageal carcinoma
ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr15:10,218,034...10,304,874
Ensembl chr15:10,218,805...10,294,316
JBrowse link
G RHOA ras homolog family member A ISO ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:26619011 NCBI chr22:10,757,381...10,809,257
Ensembl chr22:10,757,337...10,772,704
JBrowse link
G SLC7A5 solute carrier family 7 member 5 severity ISO RGD PMID:15906366 RGD:151361282 NCBI chr 5:73,229,953...73,269,801
Ensembl chr 5:73,229,951...73,269,754
JBrowse link
G SMAD4 SMAD family member 4 ISO ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:6604412 PMID:8898652 PMID:9214508 PMID:9285566 PMID:9582123 More... NCBI chr18:29,894,157...29,951,445
Ensembl chr18:29,897,621...29,934,478
JBrowse link
G STAT3 signal transducer and activator of transcription 3 treatment ISO associated with Immune Deficiency Disease, human cells in mouse model RGD PMID:25724470 RGD:127285656 NCBI chr16:63,877,884...63,957,894
Ensembl chr16:63,922,862...63,957,984
JBrowse link
G TP53 tumor protein p53 ISO ClinVar Annotator: match by term: Carcinoma of esophagus | ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:124622 PMID:253702 PMID:960674 PMID:1349175 PMID:1359493 More... NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223
JBrowse link
Esophageal Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21332314 NCBI chr21:61,211,044...61,430,691
Ensembl chr21:61,322,748...61,529,274
JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chr12:7,258,932...7,435,658
Ensembl chr12:7,256,648...7,312,734
JBrowse link
G ACTB actin beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr28:16,195,676...16,197,161
Ensembl chr12:52,426,752...52,427,879
JBrowse link
G ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:18500343 NCBI chr 7:47,571,477...47,592,502
Ensembl chr 7:47,571,564...47,590,593
JBrowse link
G AKAP13 A-kinase anchoring protein 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17068819 NCBI chr29:4,009,921...4,364,226
Ensembl chr29:4,106,732...4,359,516
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:8850269 NCBI chr11:107,019,015...107,060,784
Ensembl chr11:107,019,111...107,060,374
JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:11406566 NCBI chr16:4,112,795...4,121,764
Ensembl chr16:4,111,151...4,121,645
JBrowse link
G AQP3 aquaporin 3 (Gill blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:21401805 NCBI chr12:46,817,790...46,825,154 JBrowse link
G BAX BCL2 associated X, apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:17634542 NCBI chr 6:42,186,028...42,193,105 JBrowse link
G BBC3 BCL2 binding component 3 ISO CTD Direct Evidence: therapeutic CTD PMID:16481741 NCBI chr 6:40,560,550...40,572,428
Ensembl chr 6:40,561,274...40,567,853
JBrowse link
G BCL2 BCL2 apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895
JBrowse link
G BCL2A1 BCL2 related protein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17634542 NCBI chr26:3,451,773...3,461,215
Ensembl chr26:3,451,873...3,461,180
JBrowse link
G BSG basigin (Ok blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:36574092 NCBI chr 6:309,579...320,209
Ensembl chr 6:309,506...321,785
JBrowse link
G CASP8 caspase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17450141 PMID:21472143 NCBI chr10:86,888,654...86,944,159
Ensembl chr10:86,916,527...86,943,829
JBrowse link
G CCND1 cyclin D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12235107 NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357
JBrowse link
G CCNH cyclin H ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 4:81,373,812...81,392,454
Ensembl chr 4:81,373,994...81,392,326
JBrowse link
G CDH13 cadherin 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18729198 NCBI chr 5:68,048,655...69,213,102
Ensembl chr 5:68,451,894...69,211,534
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A disease_progression ISO RGD PMID:11903577 RGD:8662379 NCBI chr17:35,445,668...35,454,334
Ensembl chr17:35,445,223...35,454,342
JBrowse link
G CRYAB crystallin alpha B ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr 1:103,258,715...103,263,274
Ensembl chr 1:103,257,347...103,261,990
JBrowse link
G CSF3 colony stimulating factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:7692001 NCBI chr16:66,162,814...66,166,192
Ensembl chr16:66,163,681...66,165,172
JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chr26:32,074,260...32,164,926
Ensembl chr26:32,132,425...32,164,277
JBrowse link
G DCC DCC netrin 1 receptor ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr18:27,437,224...28,623,717
Ensembl chr18:27,442,489...28,212,697
JBrowse link
G EGFR epidermal growth factor receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21298351 PMID:21468131 PMID:22042947 NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239
JBrowse link
G ENO1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr20:122,884,846...122,902,669
Ensembl chr20:122,884,727...122,903,372
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22042947 NCBI chr16:66,435,488...66,464,993
Ensembl chr16:66,434,251...66,464,952
JBrowse link
G FASLG Fas ligand ISO protein:increased expression:esophageal mucosa: RGD PMID:9605741 RGD:11049151 NCBI chr25:56,488,572...56,496,469
Ensembl chr25:56,489,417...56,496,251
JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr11:6,569,029...6,572,877 JBrowse link
G GHRL ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chr22:46,326,458...46,332,906
Ensembl chr22:46,325,913...46,330,962
JBrowse link
G GNG7 G protein subunit gamma 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18219292 NCBI chr 6:2,287,339...2,485,304
Ensembl chr 6:2,287,895...2,293,067
JBrowse link
G GRIK2 glutamate ionotropic receptor kainate type subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr13:71,855,960...72,545,376
Ensembl chr13:71,855,794...72,325,857
JBrowse link
G KDR kinase insert domain receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472143 PMID:35917945 NCBI chr 7:13,435,059...13,482,236
Ensembl chr 7:13,435,096...13,482,771
JBrowse link
G LGALS3 galectin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17634542 NCBI chr24:32,311,343...32,328,335
Ensembl chr24:32,311,271...32,328,339
JBrowse link
G LOC103216270 cytochrome P450 26A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18059332 NCBI chr 9:86,310,142...86,328,622
Ensembl chr 9:86,325,401...86,328,775
JBrowse link
G LZTS1 leucine zipper tumor suppressor 1 ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr 8:18,315,243...18,377,492
Ensembl chr 8:18,315,130...18,324,345
JBrowse link
G MACIR macrophage immunometabolism regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr23:6,695,131...6,714,925
Ensembl chr23:6,712,171...6,712,791
JBrowse link
G MAP3K3 mitogen-activated protein kinase kinase kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17068819 NCBI chr16:57,594,770...57,670,047
Ensembl chr16:57,597,288...57,669,720
JBrowse link
G MARCHF8 membrane associated ring-CH-type finger 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17068819 NCBI chr 9:41,157,445...41,294,277 JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22042947 NCBI chr21:85,370,574...85,486,405
Ensembl chr21:85,397,645...85,488,093
JBrowse link
G MLH3 mutL homolog 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16981255 NCBI chr24:52,231,468...52,266,179 JBrowse link
G MMP14 matrix metallopeptidase 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chr29:23,201,425...23,212,408
Ensembl chr29:23,201,112...23,212,679
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor treatment ISO RGD PMID:22844359 RGD:7207890 NCBI chr 8:122,282,989...122,288,392
Ensembl chr 8:122,282,630...122,288,384
JBrowse link
G NOS2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15264214 NCBI chr16:21,533,011...21,576,645
Ensembl chr16:21,533,484...21,574,257
JBrowse link
G NOS3 nitric oxide synthase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chr21:119,174,829...119,196,840 JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21977915 NCBI chr22:61,005,404...61,043,016
Ensembl chr22:61,006,667...61,040,832
JBrowse link
G PHB1 prohibitin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr16:69,805,968...69,816,792
Ensembl chr16:69,806,923...69,816,754
JBrowse link
G PRDX1 peroxiredoxin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr20:87,267,026...87,277,634
Ensembl chr20:87,267,044...87,279,978
JBrowse link
G PRDX2 peroxiredoxin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr 6:11,484,452...11,489,067
Ensembl chr 6:11,481,784...11,489,051
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12189197 NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 susceptibility ISO mRNA,protein:increased expression:Esophagus
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :-1195A > G, -765G > C (human)
RGD
CTD
PMID:11059772 PMID:16083713 PMID:16322294 PMID:17707579 PMID:22165968 RGD:5135528 RGD:5687745 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429
JBrowse link
G RNF6 ring finger protein 6 ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr 3:5,461,053...5,471,268
Ensembl chr 3:5,462,126...5,468,555
JBrowse link
G RPRM reprimo, TP53 dependent G2 arrest mediator homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:17121882 NCBI chr10:38,863,940...38,865,912
Ensembl chr10:38,864,844...38,865,170
JBrowse link
G RUNX3 RUNX family transcription factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18058463 NCBI chr20:107,769,244...107,802,154
Ensembl chr20:107,736,683...107,802,307
JBrowse link
G SFN stratifin ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr20:105,902,481...105,904,313
Ensembl chr20:105,902,974...105,903,720
JBrowse link
G SLC30A7 solute carrier family 30 member 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17068819 NCBI chr20:32,355,201...32,457,491
Ensembl chr20:32,377,130...32,457,490
JBrowse link
G SMYD2 SET and MYND domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25825497 NCBI chr25:15,236,773...15,293,154
Ensembl chr25:15,235,653...15,293,153
JBrowse link
G SNAI2 snail family transcriptional repressor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17068819 NCBI chr 8:45,043,381...45,047,054
Ensembl chr 8:45,043,393...45,046,978
JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11053990 PMID:15986332 NCBI chr13:87,284,537...87,297,998
Ensembl chr13:87,280,686...87,297,974
JBrowse link
G SST somatostatin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17999418 NCBI chr15:81,946,287...81,947,775
Ensembl chr15:81,946,206...81,947,790
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10789724 NCBI chr15:75,112,903...75,200,263
Ensembl chr15:75,112,561...75,197,711
JBrowse link
G TGM2 transglutaminase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17068819 NCBI chr 2:25,585,827...25,623,961
Ensembl chr 2:25,585,865...25,624,280
JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chr 8:21,318,987...21,351,641
Ensembl chr 8:21,315,149...21,351,673
JBrowse link
G TP53 tumor protein p53 ISO protein:increased expression:esophageal mucosa:
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:12706858 PMID:16778087 PMID:17634542 PMID:26192916 PMID:26439224 RGD:11075085 RGD:8547873 NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223
JBrowse link
G TPM1 tropomyosin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr26:20,458,287...20,487,387
Ensembl chr26:20,466,037...20,487,135
JBrowse link
G TPM4 tropomyosin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr 6:14,566,958...14,604,754
Ensembl chr 6:14,566,869...14,598,934
JBrowse link
G TRMT11 tRNA methyltransferase 11 homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr13:47,680,321...47,735,103
Ensembl chr13:47,680,332...47,734,857
JBrowse link
G TUFM Tu translation elongation factor, mitochondrial ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr 5:26,221,203...26,225,080
Ensembl chr 5:26,221,337...26,225,083
JBrowse link
G UCHL1 ubiquitin C-terminal hydrolase L1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15930319 NCBI chr27:9,074,961...9,086,606
Ensembl chr27:9,074,923...9,086,517
JBrowse link
G WIF1 WNT inhibitory factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17384664 NCBI chr11:60,728,316...60,800,181
Ensembl chr11:60,727,948...60,799,960
JBrowse link
G WWOX WW domain containing oxidoreductase ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr 5:63,580,049...64,698,212
Ensembl chr 5:63,580,741...63,916,157
JBrowse link
G XIAP X-linked inhibitor of apoptosis ISO CTD Direct Evidence: marker/mechanism CTD PMID:17611394
G XRCC3 X-ray repair cross complementing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21347786 NCBI chr24:81,627,911...81,641,598
Ensembl chr24:81,630,099...81,641,218
JBrowse link
esophagus adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase onset ISO DNA:SNP:3'utr: (rs4740363) (human) RGD PMID:21472143 RGD:126925218 NCBI chr12:7,258,932...7,435,658
Ensembl chr12:7,256,648...7,312,734
JBrowse link
G ARID1A AT-rich interaction domain 1A disease_progression ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:23525077 PMID:31906887 RGD:127285649 NCBI chr20:105,981,549...106,066,093
Ensembl chr20:105,981,290...106,065,672
JBrowse link
G BARX1 BARX homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24121790 NCBI chr12:104,299,516...104,307,613
Ensembl chr12:104,303,265...104,306,251
JBrowse link
G BCL2 BCL2 apoptosis regulator onset ISO DNA:SNPs:3'utr: (rs720321, rs17757541) (human) RGD PMID:21472143 RGD:126925218 NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895
JBrowse link
G BECN1 beclin 1 ISO RGD PMID:22301112 RGD:11561943 NCBI chr16:63,469,187...63,482,627
Ensembl chr16:63,469,192...63,485,322
JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 treatment ISO RGD PMID:26291056 RGD:152999007 NCBI chr 1:93,692,239...93,711,905 JBrowse link
G CASP8 caspase 8 onset ISO DNA:SNP:5'utr: (rs1035142) (human) RGD PMID:21472143 RGD:126925218 NCBI chr10:86,888,654...86,944,159
Ensembl chr10:86,916,527...86,943,829
JBrowse link
G CDC5L cell division cycle 5 like disease_progression ISO protein:increased expression:esophageal mucosa (human) RGD PMID:15725809 RGD:10047052 NCBI chr17:27,727,185...27,785,233
Ensembl chr17:27,722,819...27,785,268
JBrowse link
G CRTC1 CREB regulated transcription coactivator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24121790 NCBI chr 6:17,146,954...17,246,209 JBrowse link
G CTSB cathepsin B ISO RGD PMID:9770500 RGD:734853 NCBI chr 8:7,246,076...7,269,655
Ensembl chr 8:7,246,013...7,268,854
JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 onset ISO DNA:SNP:5'utr: (rs2445762) (human) RGD PMID:21472143 RGD:126925218 NCBI chr26:32,074,260...32,164,926
Ensembl chr26:32,132,425...32,164,277
JBrowse link
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 treatment ISO mRNA:increased expression:esophagus (human) RGD PMID:30187205 RGD:151665176 NCBI chr 2:9,868,794...9,889,510
Ensembl chr 2:9,868,678...9,885,884
JBrowse link
G DOCK2 dedicator of cytokinesis 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23525077 NCBI chr23:71,866,196...72,299,066
Ensembl chr23:71,866,251...72,299,056
JBrowse link
G ELMO1 engulfment and cell motility 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23525077 NCBI chr21:21,066,910...21,639,149
Ensembl chr21:21,066,924...21,640,705
JBrowse link
G EMX2 empty spiracles homeobox 2 ISO protein:decreased expression:esophagus (human) RGD PMID:31432154 RGD:153323302 NCBI chr 9:110,347,043...110,353,647
Ensembl chr 9:110,347,379...110,353,643
JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit susceptibility ISO DNA:snps:cds, 3' utr:c.354C>T, c.8092C>A (human) RGD PMID:18478337 RGD:13207314 NCBI chr 6:38,857,067...38,900,177
Ensembl chr 6:38,854,803...38,872,967
JBrowse link
G FOXA1 forkhead box A1 ISO protein:increased expression:esophagus RGD PMID:12234996 RGD:151665758 NCBI chr24:14,397,759...14,403,078
Ensembl chr24:14,396,702...14,403,094
JBrowse link
G FOXP1 forkhead box P1 ISO DNA:snps:intron, enhancer:g.70959438A>G, g.70879779A>C (rs9837992, rs2687201) (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:24121790 PMID:26383589 RGD:11535321 NCBI chr22:31,907,941...32,538,294
Ensembl chr22:31,912,460...32,154,502
JBrowse link
G GHRL ghrelin and obestatin prepropeptide onset ISO DNA:SNP:5'utr: (rs696217) (human) RGD PMID:21472143 RGD:126925218 NCBI chr22:46,326,458...46,332,906
Ensembl chr22:46,325,913...46,330,962
JBrowse link
G GPX3 glutathione peroxidase 3 susceptibility ISO DNA:SNPs:intron: (rs4958872, rs3792797) (human) RGD PMID:22715394 RGD:152995500 NCBI chr23:53,576,950...53,585,321 JBrowse link
G GRB7 growth factor receptor bound protein 7 treatment
exacerbates
ISO human cells in a mouse model RGD PMID:31809243 PMID:32737994 RGD:151347656 RGD:151347659 NCBI chr16:66,416,978...66,427,035
Ensembl chr16:66,416,904...66,426,300
JBrowse link
G KDR kinase insert domain receptor onset ISO DNA:SNP:5'utr: (rs11941492) (human) RGD PMID:21472143 RGD:126925218 NCBI chr 7:13,435,059...13,482,236
Ensembl chr 7:13,435,096...13,482,771
JBrowse link
G LOC103224275 glutathione S-transferase Mu 1 ISO DNA:deletion:: (human) RGD PMID:17064856 RGD:12792242 NCBI chr20:23,854,969...23,861,634 JBrowse link
G MMP1 matrix metallopeptidase 1 susceptibility ISO DNA:insertion:promoter:g.-1607insG rs1799750 (human) RGD PMID:19321798 RGD:7207058 NCBI chr 1:94,167,507...94,177,357
Ensembl chr 1:94,167,219...94,176,767
JBrowse link
G MMP12 matrix metallopeptidase 12 ISO DNA:snp:promoter:g.-82A>G rs2276109 (human) RGD PMID:19321798 RGD:7207058 NCBI chr 1:94,243,061...94,261,035
Ensembl chr 1:94,243,875...94,259,591
JBrowse link
G MMP14 matrix metallopeptidase 14 onset ISO DNA:SNP:5'utr: (rs2236302) (human) RGD PMID:21472143 RGD:126925218 NCBI chr29:23,201,425...23,212,408
Ensembl chr29:23,201,112...23,212,679
JBrowse link
G MMP3 matrix metallopeptidase 3 ISO DNA:insertion:promoter:g.-1613insA rs3025058 (human) RGD PMID:19321798 RGD:7207058 NCBI chr 1:94,216,156...94,224,437
Ensembl chr 1:94,216,173...94,224,264
JBrowse link
G MMP9 matrix metallopeptidase 9 ISO protein:increased expression:esophagus RGD PMID:25562781 RGD:13204790 NCBI chr 2:17,867,267...17,874,757
Ensembl chr 2:17,867,177...17,874,712
JBrowse link
G NELL1 neural EGFL like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17452981 NCBI chr 1:43,416,052...44,335,894
Ensembl chr 1:43,415,553...44,335,381
JBrowse link
G NOS3 nitric oxide synthase 3 onset ISO DNA:SNP:3'utr: (rs2070744) (human) RGD PMID:21472143 RGD:126925218 NCBI chr21:119,174,829...119,196,840 JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:23525077 NCBI chr15:10,218,034...10,304,874
Ensembl chr15:10,218,805...10,294,316
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO mRNA,protein:increased expression:Esophagus RGD PMID:22165968 RGD:5687745 NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 disease_progression ISO CTD Direct Evidence: marker/mechanism
protein: increased expression: esophagus
CTD
RGD
PMID:12055587 PMID:12507933 RGD:13207437 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429
JBrowse link
G SLC22A18 solute carrier family 22 member 18 disease_progression ISO DNA:hypermethylation: (human) RGD PMID:23243219 RGD:150557426 NCBI chr 1:2,712,792...2,737,874
Ensembl chr 1:2,715,027...2,737,872
JBrowse link
G SMAD4 SMAD family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23525077 PMID:24952744 NCBI chr18:29,894,157...29,951,445
Ensembl chr18:29,897,621...29,934,478
JBrowse link
G SMO smoothened, frizzled class receptor treatment ISO RGD PMID:23108119 RGD:150340553 NCBI chr21:97,788,955...97,814,549
Ensembl chr21:97,788,624...97,814,709
JBrowse link
G SOD2 superoxide dismutase 2 ISO RGD PMID:17785574 RGD:2317403 NCBI chr13:87,284,537...87,297,998
Ensembl chr13:87,280,686...87,297,974
JBrowse link
G SPART spartin ISO CTD Direct Evidence: marker/mechanism CTD PMID:23525077 NCBI chr 3:14,887,896...14,925,296
Ensembl chr 3:14,886,633...14,924,865
JBrowse link
G TLR4 toll like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23525077 NCBI chr12:21,873,762...21,885,562
Ensembl chr12:21,871,773...21,885,515
JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a onset ISO DNA:SNP:3'utr: (rs11775256) (human) RGD PMID:21472143 RGD:126925218 NCBI chr 8:21,318,987...21,351,641
Ensembl chr 8:21,315,149...21,351,673
JBrowse link
G TP53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23525077 NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223
JBrowse link
G VDR vitamin D receptor susceptibility
disease_progression
ISO DNA:SNPs,haplotype:exon:rs1989969,rs2238135 (human)
DNA:amplication: :
RGD PMID:24951052 PMID:25910066 RGD:11055189 RGD:13432070 NCBI chr11:44,062,198...44,126,295
Ensembl chr11:44,065,457...44,166,684
JBrowse link
esophagus small cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103243443 keratin, type I cytoskeletal 14 ISO protein:increased expression:esophagus RGD PMID:16140947 RGD:1600174 NCBI chr16:64,654,988...64,660,327
Ensembl chr16:64,655,807...64,660,319
JBrowse link
esophagus squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC2 ATP binding cassette subfamily C member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21206495 NCBI chr 9:92,826,423...92,902,389
Ensembl chr 9:92,841,818...92,902,265
JBrowse link
G ADCYAP1 adenylate cyclase activating polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr18:60,259,479...60,267,302 JBrowse link
G AJUBA ajuba LIM protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr29:23,341,841...23,352,630
Ensembl chr29:23,341,249...23,352,685
JBrowse link
G AKT1 AKT serine/threonine kinase 1 disease_progression ISO protein:increased expression:esophagus (human) RGD PMID:32642408 RGD:152995512 NCBI chr24:82,704,087...82,730,711
Ensembl chr24:82,704,068...82,727,698
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:16639733 PMID:22960999 NCBI chr11:107,019,015...107,060,784
Ensembl chr11:107,019,111...107,060,374
JBrowse link
G ANXA1 annexin A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr12:84,207,818...84,226,438
Ensembl chr12:84,207,820...84,226,562
JBrowse link
G ATM ATM serine/threonine kinase disease_progression ISO Smoke Inhalation Injury; mRNA:increased expression:esophagus (human) RGD PMID:17019709 RGD:150340713 NCBI chr 1:99,653,208...99,786,889
Ensembl chr 1:99,653,139...99,791,520
JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25129146 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754
JBrowse link
G AXIN1 axin 1 disease_progression ISO protein:decreased expression:esophagus (human) RGD PMID:12771989 RGD:150530473 NCBI chr 5:233,520...295,134
Ensembl chr 5:234,060...290,575
JBrowse link
G AZGP1 alpha-2-glycoprotein 1, zinc-binding disease_progression ISO RGD PMID:28053542 RGD:153350138 NCBI chr28:13,104,262...13,120,329
Ensembl chr28:13,104,323...13,120,363
JBrowse link
G AZIN1 antizyme inhibitor 1 ISO RGD PMID:24302582 RGD:14700707 NCBI chr 8:97,679,775...97,717,486
Ensembl chr 8:97,679,468...97,696,928
JBrowse link
G B2M beta-2-microglobulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr26:38,331,818...38,338,785
Ensembl chr26:38,331,442...38,338,809
JBrowse link
G BLVRB biliverdin reductase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 6:34,902,632...34,925,105
Ensembl chr 6:34,902,598...34,925,100
JBrowse link
G BMI1 BMI1 proto-oncogene, polycomb ring finger ISO RGD PMID:21165554 RGD:126781701 NCBI chr 9:22,095,592...22,104,894 JBrowse link
G BMP6 bone morphogenetic protein 6 ISO protein:increased expression:esophagus RGD PMID:22364398 RGD:7242413 NCBI chr17:64,279,243...64,436,356
Ensembl chr17:64,280,609...64,435,382
JBrowse link
G BRCA1 BRCA1 DNA repair associated ISO DNA:SNP: :rs799917 (human) RGD PMID:23749772 RGD:126925960 NCBI chr16:63,162,827...63,243,928 JBrowse link
G BRCA2 BRCA2 DNA repair associated ISO DNA:nonsense mutation: :p.K3326X (human) RGD PMID:21279724 RGD:11344913 NCBI chr 3:11,070,086...11,155,257
Ensembl chr 3:11,071,682...11,155,213
JBrowse link
G BST2 bone marrow stromal cell antigen 2 disease_progression ISO RGD PMID:26832883 RGD:14398496 NCBI chr 6:15,900,396...15,903,072
Ensembl chr 6:15,900,011...15,903,060
JBrowse link
G BUB1B BUB1 mitotic checkpoint serine/threonine kinase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:18691855 NCBI chr26:42,769,955...42,855,353
Ensembl chr26:42,792,830...42,855,306
JBrowse link
G CA1 carbonic anhydrase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 8:80,699,114...80,729,932
Ensembl chr 8:80,699,651...80,712,858
JBrowse link
G CA12 carbonic anhydrase 12 severity ISO RGD PMID:26316888 RGD:155226859 NCBI chr26:20,162,706...20,221,680
Ensembl chr26:20,162,926...20,224,502
JBrowse link
G CA2 carbonic anhydrase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 8:80,830,963...80,848,245
Ensembl chr 8:80,830,939...80,848,707
JBrowse link
G CALR calreticulin ameliorates ISO CTD Direct Evidence: marker/mechanism
human cells in a mouse model
CTD
RGD
PMID:19684620 PMID:21517111 PMID:23814025 RGD:150521679 RGD:150521703 NCBI chr 6:11,618,691...11,624,299
Ensembl chr 6:11,618,396...11,623,792
JBrowse link
G CAPZA1 capping actin protein of muscle Z-line subunit alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr20:20,968,348...21,017,256
Ensembl chr20:20,969,828...20,991,971
JBrowse link
G CASP8 caspase 8 exacerbates ISO mRNA,protein:decreased expression:esophagus squamous epithelium (human) RGD PMID:31885720 RGD:153300949 NCBI chr10:86,888,654...86,944,159
Ensembl chr10:86,916,527...86,943,829
JBrowse link
G CBX8 chromobox 8 severity ISO mRNA:increased expression:esophagus: RGD PMID:25197352 RGD:9587436 NCBI chr16:71,755,598...71,760,611
Ensembl chr16:71,755,627...71,760,632
JBrowse link
G CCHCR1 coiled-coil alpha-helical rod protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chr17:41,319,392...41,334,661
Ensembl chr17:41,319,423...41,334,502
JBrowse link
G CCND1 cyclin D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A ISO CTD Direct Evidence: therapeutic CTD PMID:15375580 NCBI chr17:35,445,668...35,454,334
Ensembl chr17:35,445,223...35,454,342
JBrowse link
G CFL1 cofilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 1:8,408,560...8,410,564 JBrowse link
G CHRNA5 cholinergic receptor nicotinic alpha 5 subunit susceptibility ISO DNA:SNP: :rs667282(human)
mRNA:increased expression:esophagus (human)
RGD PMID:23844051 PMID:27610024 RGD:150524358 RGD:151361143 NCBI chr26:4,747,734...4,779,231
Ensembl chr26:4,749,766...4,776,822
JBrowse link
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit exacerbates
disease_progression
ISO mRNA:increased expression:esophagus (human) RGD PMID:27610024 PMID:33603170 RGD:151361143 RGD:151667905 NCBI chr26:50,554,143...50,686,847
Ensembl chr26:50,551,829...50,686,803
JBrowse link
G CHRNB4 cholinergic receptor nicotinic beta 4 subunit ISO mRNA:increased expression:esophagus (human) RGD PMID:27610024 RGD:151361143 NCBI chr26:4,700,217...4,717,363
Ensembl chr26:4,701,321...4,719,319
JBrowse link
G CLIC1 chloride intracellular channel 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr17:40,286,051...40,292,377
Ensembl chr17:40,286,491...40,292,113
JBrowse link
G CLPTM1L CLPTM1 like susceptibility
no_association
ISO DNA:SNP: :rs401681(human)
mRNA:increased expression:esophagus
DNA:SNP: :rs451360(human)
RGD PMID:24386361 PMID:25007268 PMID:25480402 PMID:26716642 RGD:11572962 RGD:150530488 RGD:150530497 RGD:150537098 NCBI chr 4:1,140,272...1,162,663
Ensembl chr 4:1,140,132...1,162,898
JBrowse link
G COL14A1 collagen type XIV alpha 1 chain disease_progression ISO DNA:hypermethylation RGD PMID:25050929 RGD:151665741 NCBI chr 8:114,701,662...114,946,216
Ensembl chr 8:114,701,664...114,887,483
JBrowse link
G CRABP1 cellular retinoic acid binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17438526 NCBI chr26:4,987,927...4,996,431
Ensembl chr26:4,987,882...4,996,343
JBrowse link
G CREBBP CREB binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 5:3,415,548...3,570,030
Ensembl chr 5:3,415,412...3,540,943
JBrowse link
G CSF1R colony stimulating factor 1 receptor ISO mRNA:decreased expression:esophagus squamous epithelium (human) RGD PMID:32038997 RGD:150524298 NCBI chr23:52,663,290...52,723,652
Ensembl chr23:52,664,076...52,697,304
JBrowse link
G CSTB cystatin B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 2:87,551,341...87,555,145 JBrowse link
G CTNNB1 catenin beta 1 ISO ClinVar Annotator: match by term: Esophageal squamous cell carcinoma ClinVar PMID:25157968 PMID:25741868 PMID:26619011 NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 severity ISO mRNA:increased expression:esophagus (human) RGD PMID:31423201 RGD:150520019 NCBI chr 7:22,202,497...22,205,730
Ensembl chr 7:22,202,527...22,204,068
JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 disease_progression ISO protein:increased expression:esophagus squamous epithelium (human) RGD PMID:17171785 RGD:152023646 NCBI chr10:20,336,470...20,340,308
Ensembl chr10:20,336,247...20,340,309
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO RGD PMID:11860825 RGD:14700943 NCBI chr26:8,753,236...8,759,378
Ensembl chr26:8,753,327...8,759,384
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 ISO protein:increased expression:esophagus (rat) RGD PMID:18618592 RGD:7829715 NCBI chr14:69,318,713...69,327,277
Ensembl chr14:69,319,495...69,324,157
JBrowse link
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 susceptibility ISO DNA:SNP:CDS: (rs2296241) (human) RGD PMID:28362172 RGD:151665500 NCBI chr 2:9,868,794...9,889,510
Ensembl chr 2:9,868,678...9,885,884
JBrowse link
G CYP26B1 cytochrome P450 family 26 subfamily B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chr14:35,030,011...35,057,164
Ensembl chr14:35,038,654...35,057,176
JBrowse link
G DAB2IP DAB2 interacting protein severity ISO protein:decreased expression:esophagus (human) RGD PMID:30464518 RGD:151665168 NCBI chr12:17,802,030...18,017,648
Ensembl chr12:17,801,831...17,830,890
JBrowse link
G DCC DCC netrin 1 receptor ISO OMIM NCBI chr18:27,437,224...28,623,717
Ensembl chr18:27,442,489...28,212,697
JBrowse link
G DIDO1 death inducer-obliterator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30431698 NCBI chr 2:1,285,027...1,345,726
Ensembl chr 2:1,285,051...1,345,846
JBrowse link
G DNMT3B DNA methyltransferase 3 beta disease_progression ISO protein:increased expression:nucleus: RGD PMID:22213175 RGD:9589085 NCBI chr 2:37,128,635...37,176,033
Ensembl chr 2:37,146,538...37,174,570
JBrowse link
G DPP4 dipeptidyl peptidase 4 ISO protein:increased expression: esophagus RGD PMID:24789592 RGD:152600903 NCBI chr10:47,396,605...47,481,478
Ensembl chr10:47,394,093...47,480,893
JBrowse link
G EFNB2 ephrin B2 severity
exacerbates
ameliorates
ISO mRNA:increased expression:esophagus squamous epithelium (human)
mRNA,protein:increased expression:esophagus squamous epithelium (human)
human cells in mouse model
RGD PMID:17611172 PMID:29190834 PMID:31885720 RGD:153300947 RGD:153300948 RGD:153300949 NCBI chr 3:84,904,421...84,949,292
Ensembl chr 3:84,904,435...84,949,465
JBrowse link
G EGFR epidermal growth factor receptor severity ISO protein:increased expression:esophagus (human)
ClinVar Annotator: match by term: Esophageal squamous cell carcinoma
RGD
ClinVar
PMID:10385363 PMID:23485129 PMID:25157968 RGD:5131486 NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239
JBrowse link
G EHMT1 euchromatic histone lysine methyltransferase 1 disease_progression ISO protein:increased expression:esophagus:
protein:increased expression:esophagus mucosa:
RGD PMID:24649311 PMID:24805087 RGD:9589143 RGD:9590071 NCBI chr12:380,041...545,333
Ensembl chr12:379,943...497,033
JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 disease_progression ISO protein:increased expression:esophagus mucosa: RGD PMID:24805087 RGD:9590071 NCBI chr17:40,123,935...40,141,942
Ensembl chr17:40,124,640...40,141,616
JBrowse link
G EP300 E1A binding protein p300 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17965222 PMID:25151357 NCBI chr19:23,634,132...23,726,095
Ensembl chr19:23,634,571...23,724,979
JBrowse link
G EPB41L3 erythrocyte membrane protein band 4.1 like 3 disease_progression ISO DNA:hypermethylation RGD PMID:25050929 RGD:151665741 NCBI chr18:64,489,194...64,704,733
Ensembl chr18:64,489,042...64,585,973
JBrowse link
G EPHB4 EPH receptor B4 exacerbates ISO mRNA,protein:increased expression:esophagus squamous epithelium (human) RGD PMID:31885720 RGD:153300949 NCBI chr28:12,389,884...12,416,746
Ensembl chr28:12,389,942...12,416,920
JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 disease_progression
susceptibility
ISO protein:altered localization:nucleus
DNA:SNPs, haplotypes: :rs1595066 and rs16845990 (human)
RGD PMID:18000820 PMID:24916311 RGD:126781764 RGD:126781765 NCBI chr10:97,099,090...98,281,697 JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit treatment ISO RGD PMID:23263828 RGD:11252162 NCBI chr 6:38,857,067...38,900,177
Ensembl chr 6:38,854,803...38,872,967
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit disease_progression ISO RGD PMID:21165554 PMID:25613619 RGD:126781697 RGD:126781701 NCBI chr21:117,380,518...117,515,224
Ensembl chr21:117,380,361...117,421,573
JBrowse link
G FANCA FA complementation group A ISO DNA:missense mutation: :p.S858R (human) RGD PMID:21279724 RGD:11344913 NCBI chr 5:75,073,161...75,149,110
Ensembl chr 5:75,073,358...75,148,591
JBrowse link
G FAP fibroblast activation protein alpha ISO protein:increased expression: esophagus RGD PMID:24789592 RGD:152600903 NCBI chr10:47,578,164...47,652,179
Ensembl chr10:47,577,888...47,652,689
JBrowse link
G FASN fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chr16:73,988,410...74,008,374
Ensembl chr16:73,982,899...74,006,551
JBrowse link
G FAT1 FAT atypical cadherin 1 ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:esophagus squamous epithelium (human)
CTD
RGD
PMID:24590895 PMID:25151357 PMID:29365412 RGD:151347630 RGD:151347646 NCBI chr 7:132,475,689...132,616,151
Ensembl chr 7:132,483,032...132,616,112
JBrowse link
G FAT2 FAT atypical cadherin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr23:54,064,687...54,152,696
Ensembl chr23:54,064,393...54,152,416
JBrowse link
G FAT3 FAT atypical cadherin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 1:83,471,266...84,159,858
Ensembl chr 1:83,609,116...84,158,537
JBrowse link
G FAT4 FAT atypical cadherin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 7:72,498,182...72,686,607
Ensembl chr 7:72,500,264...72,685,546
JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 7:98,894,261...99,105,955
Ensembl chr 7:98,892,504...99,106,084
JBrowse link
G FES FES proto-oncogene, tyrosine kinase exacerbates ISO DNA:hypermethylation: (human) RGD PMID:24936140 RGD:153323298 NCBI chr29:8,967,542...8,979,475
Ensembl chr29:8,965,997...8,979,361
JBrowse link
G FGFR4 fibroblast growth factor receptor 4 treatment ISO RGD PMID:25989802 RGD:150520041 NCBI chr23:79,095,031...79,106,018
Ensembl chr23:79,097,429...79,105,456
JBrowse link
G FKBP1A FKBP prolyl isomerase 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 2:55,170,816...55,195,380 JBrowse link
G FOXA1 forkhead box A1 onset ISO DNA:SNPs: :rs12894364 C>T, rs2145146 C>A (human) RGD PMID:27050876 PMID:29788741 RGD:151665743 RGD:151665759 NCBI chr24:14,397,759...14,403,078
Ensembl chr24:14,396,702...14,403,094
JBrowse link
G FUBP1 far upstream element binding protein 1 exacerbates ISO protein:increased expression:esophagus (human)
mRNA:increased expression:esophagus (human)
RGD PMID:26490982 PMID:32481602 RGD:151361192 RGD:151361197 NCBI chr20:55,194,681...55,233,666
Ensembl chr20:55,194,743...55,230,277
JBrowse link
G GDI2 GDP dissociation inhibitor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 9:5,876,245...5,923,011
Ensembl chr 9:5,877,042...5,922,968
JBrowse link
G GLO1 glyoxalase I ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr17:33,446,134...33,472,240
Ensembl chr17:33,446,145...33,473,699
JBrowse link
G GPX3 glutathione peroxidase 3 disease_progression ISO DNA:hypermethylation RGD PMID:25050929 PMID:30018730 RGD:151665494 RGD:151665741 NCBI chr23:53,576,950...53,585,321 JBrowse link
G GRB7 growth factor receptor bound protein 7 exacerbates ISO protein:increased expression:esophagus (human)
mRNA:increased expression:esophagus mucosa (human)
RGD PMID:10797316 PMID:26465158 RGD:151347654 RGD:151347661 NCBI chr16:66,416,978...66,427,035
Ensembl chr16:66,416,904...66,426,300
JBrowse link
G GSTO1 glutathione S-transferase omega 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 9:97,305,094...97,317,892 JBrowse link
G GSTP1 glutathione S-transferase pi 1 ISO DNA:polymorphism: :p.I105V (human) RGD PMID:17916905 RGD:14700982 NCBI chr 1:6,676,897...6,679,936 JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:17201171 NCBI chr24:38,873,830...38,927,657
Ensembl chr24:38,873,861...38,928,288
JBrowse link
G HMGB1 high mobility group box 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 3:9,353,333...9,357,765 JBrowse link
G HMGN5 high mobility group nucleosome binding domain 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28914995 NCBI chr  X:70,103,170...70,201,472
Ensembl chr  X:70,102,034...70,111,019
JBrowse link
G HOXB7 homeobox B7 severity ISO protein:increased expression:esophageal mucosa (human) RGD PMID:26076456 RGD:10402177 NCBI chr16:69,020,325...69,024,362
Ensembl chr16:69,020,906...69,023,671
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr12:12,920,705...12,925,888
Ensembl chr12:12,920,710...12,927,431
JBrowse link
G HTRA1 HtrA serine peptidase 1 exacerbates
ameliorates
ISO mRNA,protein:decreased expression:epithelium of esophagus (human)
human gene and cells in mouse model
RGD PMID:23079781 RGD:152975633 NCBI chr 9:115,197,543...115,250,092
Ensembl chr 9:115,197,566...115,253,919
JBrowse link
G JAK2 Janus kinase 2 severity ISO protein:increased phosphorylation:esophagus squamous epithelium (human) RGD PMID:32158193 RGD:127285669 NCBI chr12:74,421,243...74,566,766
Ensembl chr12:74,421,016...74,566,710
JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit exacerbates ISO protein:increased expression:esophagus (human) RGD PMID:19758438 PMID:30227324 RGD:151347669 RGD:151347672 NCBI chr 6:11,479,108...11,480,942
Ensembl chr 6:11,479,407...11,480,450
JBrowse link
G KAT2B lysine acetyltransferase 2B ISO mRNA:decreased expression:esophagus (human) RGD PMID:19525977 RGD:9590307 NCBI chr15:64,769,590...64,885,536
Ensembl chr15:64,770,185...64,886,219
JBrowse link
G KDM4C lysine demethylase 4C severity
susceptibility
ISO protein:increased expression:esophageal epithelium, nucleus (human)
DNA:snp:intron:IVS8-3292G>A (rs1340513) (human)
RGD PMID:15805246 PMID:24224128 RGD:9587746 RGD:9587752 NCBI chr12:72,346,194...72,763,040
Ensembl chr12:72,347,071...72,761,666
JBrowse link
G KDM5B lysine demethylase 5B severity ISO protein:increased expression:esophageal mucosa, cytoplasm (human) RGD PMID:22534467 RGD:9587776 NCBI chr25:26,599,740...26,685,256
Ensembl chr25:26,600,736...26,683,632
JBrowse link
G KDM6A lysine demethylase 6A ameliorates ISO DNA:mutations:multiple (human)
protein:increased expression:esophagus (human)
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:esophagus (human)
RGD
CTD
PMID:25151357 PMID:29351209 PMID:31804468 RGD:150429739 RGD:150429742 RGD:9588233 NCBI chr  X:42,053,272...42,291,013
Ensembl chr  X:42,053,336...42,290,526
JBrowse link
G KMT2C lysine methyltransferase 2C ISO CTD Direct Evidence: marker/mechanism
DNA:mutations:multiple (human)
CTD
RGD
PMID:25151357 RGD:9588233 NCBI chr21:120,299,295...120,587,843
Ensembl chr21:120,301,188...120,587,137
JBrowse link
G KMT2D lysine methyltransferase 2D ISO DNA:mutations:multiple (human)
mRNA:increased expression:esophagus
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:25151357 PMID:29532228 RGD:150521712 RGD:9588233 NCBI chr11:45,260,873...45,303,898
Ensembl chr11:45,263,408...45,302,423
JBrowse link
G KRT13 keratin 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr16:64,735,285...64,740,791 JBrowse link
G KRT16 keratin 16 ISO RGD PMID:8950218 RGD:633113 NCBI chr16:64,629,385...64,633,125
Ensembl chr16:64,630,042...64,633,114
JBrowse link
G KRT17 keratin 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr16:64,615,194...64,622,931
Ensembl chr16:64,617,219...64,622,971
JBrowse link
G KRT19 keratin 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr16:64,714,497...64,719,805
Ensembl chr16:64,714,970...64,719,678
JBrowse link
G KRT7 keratin 7 disease_progression ISO RGD PMID:29788741 RGD:151665759 NCBI chr11:48,379,460...48,394,638
Ensembl chr11:48,379,465...48,394,643
JBrowse link
G LOC103219825 protein patched homolog 1 disease_progression ISO RGD PMID:16475698 RGD:150523841 NCBI chr12:107,580,895...107,656,443
Ensembl chr12:107,590,663...107,652,985
JBrowse link
G LOC103221937 histone H2B type 1-M ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr17:44,715,875...44,716,426
Ensembl chr17:44,715,922...44,716,299
JBrowse link
G LOC103224275 glutathione S-transferase Mu 1 no_association ISO RGD PMID:11860825 PMID:17916905 PMID:25432134 RGD:14700943 RGD:14700948 RGD:14700982 NCBI chr20:23,854,969...23,861,634 JBrowse link
G LOC103231165 isocitrate dehydrogenase (NADP(+)) 2 severity ISO human cells in mouse model RGD PMID:32367071 RGD:149735568 NCBI chr29:8,633,429...8,650,744
Ensembl chr29:8,633,715...8,650,657
JBrowse link
G LOC103233044 metallothionein-1X ISO CTD Direct Evidence: marker/mechanism CTD PMID:16543248 NCBI chr 5:42,637,027...42,638,751
Ensembl chr 5:42,637,113...42,638,611
JBrowse link
G LOC103243443 keratin, type I cytoskeletal 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16543248 NCBI chr16:64,654,988...64,660,327
Ensembl chr16:64,655,807...64,660,319
JBrowse link
G LOXL2 lysyl oxidase like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24716982 NCBI chr 8:21,416,821...21,516,923
Ensembl chr 8:21,416,787...21,516,854
JBrowse link
G LTA lymphotoxin alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:29379198
G LZTS1 leucine zipper tumor suppressor 1 ISO ClinVar Annotator: match by term: Esophageal squamous cell carcinoma, somatic | ClinVar Annotator: match by term: LZTS1-related condition OMIM
ClinVar
PMID:10097140 PMID:25741868 PMID:26504261 PMID:28492532 NCBI chr 8:18,315,243...18,377,492
Ensembl chr 8:18,315,130...18,324,345
JBrowse link
G MAD2L1 mitotic arrest deficient 2 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18691855 NCBI chr 7:67,351,785...67,360,244 JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 sexual_dimorphism ISO DNA:missense mutation, SNP:CDS, exon 14, 3'-UTR: (rs702689,rs702688) (human) RGD PMID:32753933 RGD:150573717 NCBI chr 4:53,040,731...53,120,784
Ensembl chr 4:53,084,023...53,120,772
JBrowse link
G MBD4 methyl-CpG binding domain 4, DNA glycosylase susceptibility ISO DNA:snp:intron:IVS5-140A>G (rs3138355) (human)
DNA:snp:cds:p.E346K (rs140693) (human)
RGD PMID:15205355 PMID:25162968 RGD:9588976 RGD:9588980 NCBI chr22:51,616,840...51,626,232
Ensembl chr22:51,616,803...51,626,224
JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase disease_progression ISO DNA, protein:hypermethylation, decreased expression:promoter, esophagus
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:21674174 PMID:25520135 RGD:126790574 NCBI chr 9:122,089,768...122,376,320 JBrowse link
G MLH1 mutL homolog 1 disease_progression ISO DNA, protein:hypermethylation, decreased expression:promoter, esophagus RGD PMID:21674174 RGD:126790574 NCBI chr15:2,364,537...2,418,379
Ensembl chr15:2,364,738...2,418,393
JBrowse link
G MMP14 matrix metallopeptidase 14 ISO protein:increased expression: esophagus RGD PMID:24789592 RGD:152600903 NCBI chr29:23,201,425...23,212,408
Ensembl chr29:23,201,112...23,212,679
JBrowse link
G MMP2 matrix metallopeptidase 2 ISO protein:increased activity: esophagus RGD PMID:24789592 RGD:152600903 NCBI chr 5:41,264,382...41,291,657
Ensembl chr 5:41,264,354...41,291,004
JBrowse link
G MMP9 matrix metallopeptidase 9 ISO protein:increased activity: esophagus RGD PMID:24789592 RGD:152600903 NCBI chr 2:17,867,267...17,874,757
Ensembl chr 2:17,867,177...17,874,712
JBrowse link
G MSH2 mutS homolog 2 disease_progression ISO DNA, protein:hypermethylation, decreased expression:promoter, esophagus
DNA, protein:hypermethylation, decreased expression:esophagus
RGD PMID:21674174 PMID:22265839 PMID:24366688 RGD:126790560 RGD:126790573 RGD:126790574 NCBI chr14:59,730,101...59,802,857
Ensembl chr14:59,729,789...59,802,819
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr10:62,789,647...62,825,651
Ensembl chr10:62,790,124...62,825,339
JBrowse link
G NOTCH1 notch receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr12:1,656,815...1,707,566
Ensembl chr12:1,656,918...1,709,585
JBrowse link
G NOTCH2 notch receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr20:13,712,140...13,871,777
Ensembl chr20:13,712,292...13,871,784
JBrowse link
G NOTCH3 notch receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 6:13,762,570...13,803,676
Ensembl chr 6:13,761,512...13,793,359
JBrowse link
G PAGR1 PAXIP1 associated glutamate rich protein 1 ISO mRNA, protein:decreased expression:esophagus (human) RGD PMID:33833989 RGD:153344568 NCBI chr 5:26,833,333...26,837,655
Ensembl chr 5:26,833,675...26,837,640
JBrowse link
G PBX3 PBX homeobox 3 ISO RNA:increased expression:esophagus squamous epithelium (human) RGD PMID:32449803 RGD:153345544 NCBI chr12:12,174,407...12,400,184 JBrowse link
G PFN1 profilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr16:4,426,853...4,430,259
Ensembl chr16:4,426,962...4,429,713
JBrowse link
G PLCE1 phospholipase C epsilon 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20729852 PMID:20729853 NCBI chr 9:87,214,166...87,559,010
Ensembl chr 9:87,214,355...87,555,733
JBrowse link
G PRDX1 peroxiredoxin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr20:87,267,026...87,277,634
Ensembl chr20:87,267,044...87,279,978
JBrowse link
G PSMB9 proteasome 20S subunit beta 9 disease_progression ISO RGD PMID:19492245 RGD:6482249 NCBI chr17:39,246,356...39,251,852
Ensembl chr17:39,245,854...39,251,842
JBrowse link
G PSME1 proteasome activator subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr24:1,122,086...1,124,907
Ensembl chr24:1,122,631...1,125,416
JBrowse link
G PSME2 proteasome activator subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr24:1,129,389...1,133,289
Ensembl chr24:1,129,419...1,132,596
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15756444 PMID:16543248 PMID:18197933 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429
JBrowse link
G PTPRT protein tyrosine phosphatase receptor type T susceptibility ISO DNA:SNPs:3'utr: (rs2866943 , rs6029959 ) (human) RGD PMID:25967969 RGD:150520191 NCBI chr 2:20,613,352...21,720,417 JBrowse link
G RB1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 3:26,220,783...26,393,671
Ensembl chr 3:26,220,803...26,394,546
JBrowse link
G RICTOR RPTOR independent companion of MTOR complex 2 severity
disease_progression
ISO protein:increased expression:esophagus (human)
human cells in mouse model
RGD PMID:28132115 PMID:30119206 PMID:32642408 RGD:152995460 RGD:152995470 RGD:152995512 NCBI chr 4:37,758,531...37,885,323
Ensembl chr 4:37,762,901...37,873,766
JBrowse link
G RNF6 ring finger protein 6 ISO ClinVar Annotator: match by term: Esophageal squamous cell carcinoma, somatic ClinVar
OMIM
PMID:12154016 NCBI chr 3:5,461,053...5,471,268
Ensembl chr 3:5,462,126...5,468,555
JBrowse link
G RUNX2 RUNX family transcription factor 2 ISO mRNA:increased expression:esophagus mucosa RGD PMID:18500170 RGD:126779568 NCBI chr17:26,679,386...26,807,812
Ensembl chr17:26,683,175...26,807,319
JBrowse link
G RUNX3 RUNX family transcription factor 3 disease_progression ISO mRNA:decreased expression:esophagus mucosa RGD PMID:18500170 RGD:126779568 NCBI chr20:107,769,244...107,802,154
Ensembl chr20:107,736,683...107,802,307
JBrowse link
G SALL4 spalt like transcription factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30431698 NCBI chr 2:12,179,721...12,199,629
Ensembl chr 2:12,182,357...12,199,321
JBrowse link
G SETD5 SET domain containing 5 disease_progression ISO RGD PMID:31981592 RGD:155804254 NCBI chr22:45,391,871...45,475,183
Ensembl chr22:45,430,660...45,475,217
JBrowse link
G SFN stratifin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr20:105,902,481...105,904,313
Ensembl chr20:105,902,974...105,903,720
JBrowse link
G SLC16A10 solute carrier family 16 member 10 ISO protein:increased expression:esophagus RGD PMID:33609949 RGD:151361149 NCBI chr13:62,645,692...62,787,508
Ensembl chr13:62,646,876...62,786,048
JBrowse link
G SLC1A5 solute carrier family 1 member 5 disease_progression ISO protein:increased expression:esophagus RGD PMID:26936531 PMID:33609949 RGD:11532833 RGD:151361149 NCBI chr 6:40,139,417...40,150,312 JBrowse link
G SLC39A6 solute carrier family 39 member 6 ISO CTD Direct Evidence: therapeutic CTD PMID:23644492 NCBI chr18:44,681,718...44,702,741
Ensembl chr18:44,681,508...44,702,754
JBrowse link
G SLC52A3 solute carrier family 52 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20729853 NCBI chr 2:55,744,934...55,760,957
Ensembl chr 2:55,752,837...55,761,120
JBrowse link
G SLC7A5 solute carrier family 7 member 5 disease_progression ISO protein:increased expression:esophagus RGD PMID:26936531 PMID:31726270 PMID:33609949 RGD:11532833 RGD:151361144 RGD:151361149 NCBI chr 5:73,229,953...73,269,801
Ensembl chr 5:73,229,951...73,269,754
JBrowse link
G SOCS1 suppressor of cytokine signaling 1 severity
treatment
ISO mRNA:decreased expression:esophagus RGD PMID:21385099 PMID:28233302 PMID:31728180 RGD:150573691 RGD:150573812 RGD:150573815 NCBI chr 5:10,731,866...10,733,745
Ensembl chr 5:10,732,350...10,732,991
JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18167182 PMID:21517111 NCBI chr13:87,284,537...87,297,998
Ensembl chr13:87,280,686...87,297,974
JBrowse link
G SOX2 SRY-box transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19801978 NCBI chr15:7,673,581...7,676,812
Ensembl chr15:7,674,867...7,675,826
JBrowse link
G SPEN spen family transcriptional repressor ISO associated with Neoplasm Metastasis; DNA:mutations RGD PMID:33363385 RGD:151347445 NCBI chr20:116,359,981...116,458,156
Ensembl chr20:116,361,008...116,458,064
JBrowse link
G STIM1 stromal interaction molecule 1 exacerbates ISO protein:increased expression:esophagus (human) RGD PMID:31843504 RGD:152995393 NCBI chr 1:62,651,472...62,865,992
Ensembl chr 1:62,651,290...62,865,986
JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25129146 NCBI chr23:42,153,576...42,160,903
Ensembl chr23:42,153,026...42,160,907
JBrowse link
G TAGLN transgelin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 1:108,570,342...108,575,789
Ensembl chr 1:108,574,007...108,575,348
JBrowse link
G TAP1 transporter 1, ATP binding cassette subfamily B member ISO protein:decreased expression:esophagus RGD PMID:19492245 RGD:6482249 NCBI chr17:39,252,000...39,260,195 JBrowse link
G TAP2 transporter 2, ATP binding cassette subfamily B member ISO protein:decreased expression:esophagus RGD PMID:19492245 RGD:6482249 NCBI chr17:39,266,870...39,277,658 JBrowse link
G TCN2 transcobalamin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chr19:13,489,849...13,511,360
Ensembl chr19:13,490,645...13,511,810
JBrowse link
G TERT telomerase reverse transcriptase no_association
susceptibility
ISO DNA:SNP: :rs2736098(human)
mRNA:increased expression:esophagus squamous epithelium:
DNA:SNPs: : rs2853691,rs2736100(human)
RGD PMID:15112252 PMID:25007268 PMID:26716642 RGD:11572962 RGD:150530488 RGD:152977757 NCBI chr 4:1,082,894...1,119,373
Ensembl chr 4:1,083,384...1,117,468
JBrowse link
G TET2 tet methylcytosine dioxygenase 2 severity ISO mRNA:decreased expression:esophagus squamous epithelium (human)
associated with Lymphatic Metastasis;mRNA:decreased expression:esophagus squamous epithelium (human)
DNA:mutations
RGD PMID:26093090 PMID:26873401 PMID:27050164 RGD:11528815 RGD:150429656 RGD:150429668 NCBI chr 7:53,193,824...53,326,813
Ensembl chr 7:53,193,941...53,326,942
JBrowse link
G TET3 tet methylcytosine dioxygenase 3 ISO mRNA:decreased expression:esophagus squamous epithelium (human) RGD PMID:27050164 RGD:150429668 NCBI chr14:33,170,046...33,293,128
Ensembl chr14:33,176,039...33,293,906
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO OMIM NCBI chr15:75,112,903...75,200,263
Ensembl chr15:75,112,561...75,197,711
JBrowse link
G TNFAIP3 TNF alpha induced protein 3 severity ISO mRNA,protein:increased expression:esophagus squamous epithelium (human) RGD PMID:28197630 RGD:151347617 NCBI chr13:35,537,103...35,553,396
Ensembl chr13:35,537,102...35,549,197
JBrowse link
G TNFAIP8 TNF alpha induced protein 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21969086 NCBI chr23:22,514,427...22,636,888
Ensembl chr23:22,573,208...22,636,936
JBrowse link
G TNXB tenascin XB ISO CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chr17:39,919,839...39,988,087
Ensembl chr17:39,919,772...39,986,868
JBrowse link
G TP53 tumor protein p53 ISO DNA:misssense mutation: :p.R72P (rs1042522) (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:16543248 PMID:25151357 PMID:28789369 RGD:14995932 NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223
JBrowse link
G TPI1 triosephosphate isomerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr11:6,900,762...6,904,188
Ensembl chr11:6,900,787...6,906,787
JBrowse link
G TPM1 tropomyosin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr26:20,458,287...20,487,387
Ensembl chr26:20,466,037...20,487,135
JBrowse link
G TPM2 tropomyosin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr12:44,912,250...44,920,615
Ensembl chr12:44,912,223...44,919,456
JBrowse link
G TXNDC17 thioredoxin domain containing 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr16:6,016,273...6,018,500 JBrowse link
G TYMP thymidine phosphorylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:11641616 NCBI chr19:32,997,337...33,001,558
Ensembl chr19:32,997,304...33,001,215
JBrowse link
G USP8 ubiquitin specific peptidase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35022897 NCBI chr26:32,829,627...32,906,493
Ensembl chr26:32,829,523...32,866,073
JBrowse link
G VENTX VENT homeobox ISO CTD Direct Evidence: marker/mechanism CTD PMID:30431698
G WRAP53 WD repeat containing antisense to TP53 disease_progression ISO RGD PMID:24626331 RGD:21081532 NCBI chr16:7,065,531...7,085,590
Ensembl chr16:7,066,333...7,085,625
JBrowse link
G WWOX WW domain containing oxidoreductase ISO ClinVar Annotator: match by term: Esophageal squamous cell carcinoma, somatic ClinVar
OMIM
PMID:11956080 PMID:28492532 NCBI chr 5:63,580,049...64,698,212
Ensembl chr 5:63,580,741...63,916,157
JBrowse link
G XPO1 exportin 1 exacerbates ISO mRNA, protein:increased expression:epithelium of esophagus (human)
protein:increased expression:esophagus (human)
RGD PMID:24898882 PMID:25148895 RGD:151667431 RGD:151667436 NCBI chr14:45,428,279...45,487,965
Ensembl chr14:45,432,619...45,488,723
JBrowse link
G XRCC1 X-ray repair cross complementing 1 susceptibility
no_association
treatment
ISO CTD Direct Evidence: marker/mechanism
DNA:SNPs,haplotypes:multiple (human)
DNA:missense mutation:cds: p.R399Q (human)
DNA:SNPs:exon 6, exon 9, exon 10:multiple (human)
CTD
RGD
PMID:11400117 PMID:16639733 PMID:25710005 PMID:27123143 PMID:28356949 RGD:150530501 RGD:150530505 RGD:150530634 RGD:151347444 NCBI chr 6:37,062,149...37,095,138
Ensembl chr 6:37,060,439...37,095,094
JBrowse link
G ZCCHC12 zinc finger CCHC-type containing 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30431698
Familial Cystic Parathyroid Adenomatosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC73 cell division cycle 73 ISO ClinVar Annotator: match by term: Cystic parathyroid adenoma ClinVar PMID:12434154 NCBI chr25:36,167,482...36,302,918
Ensembl chr25:36,170,134...36,302,812
JBrowse link
familial medullary thyroid carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INSRR insulin receptor related receptor ISO ClinVar Annotator: match by term: Familial medullary thyroid carcinoma | ClinVar Annotator: match by term: Thyroid cancer, familial medullary ClinVar NCBI chr20:7,008,882...7,029,377
Ensembl chr20:7,010,504...7,028,557
JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 ISO ClinVar Annotator: match by term: Familial medullary thyroid carcinoma | ClinVar Annotator: match by term: Thyroid cancer, familial medullary ClinVar PMID:10330344 PMID:10443680 PMID:10861667 PMID:11139246 PMID:11159935 More... NCBI chr20:6,987,903...7,027,381
Ensembl chr20:6,987,905...7,008,670
JBrowse link
G PRLR prolactin receptor ISO OMIM:155240 MouseDO NCBI chr 4:33,933,601...34,108,653
Ensembl chr 4:33,949,935...34,108,619
JBrowse link
G RET ret proto-oncogene ISO ClinVar Annotator: match by term: Familial medullary thyroid carcinoma | ClinVar Annotator: match by term: Thyroid cancer, familial medullary OMIM
ClinVar
PMID:2660074 PMID:3078962 PMID:3697657 PMID:7536460 PMID:7595170 More... NCBI chr 9:38,746,088...38,798,773
Ensembl chr 9:38,769,170...38,796,712
JBrowse link
Follicular Thyroid Cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRAF B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2 ClinVar PMID:12068308 PMID:12198537 PMID:12960123 PMID:14679157 PMID:15035987 More... NCBI chr21:109,495,525...109,690,261 JBrowse link
G CBX7 chromobox 7 ISO protein:decreased expression:thyroid gland: RGD PMID:18701502 RGD:9587357 NCBI chr19:21,776,618...21,798,525
Ensembl chr19:21,775,931...21,798,309
JBrowse link
G CGA glycoprotein hormones, alpha polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:10566621 NCBI chr13:11,560,543...11,578,070
Ensembl chr13:11,560,222...11,578,093
JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: THYROID CANCER, NONMEDULLARY, 2 | ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2 OMIM
ClinVar
PMID:12727991 PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 More... NCBI chr 1:343,613...345,782
Ensembl chr 1:343,506...346,637
JBrowse link
G LRRC56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: THYROID CANCER, NONMEDULLARY, 2 | ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2 ClinVar PMID:12727991 PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 More... NCBI chr 1:352,131...370,276
Ensembl chr 1:355,982...369,633
JBrowse link
G MINPP1 multiple inositol-polyphosphate phosphatase 1 ISO ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2 OMIM
ClinVar
PMID:11297621 NCBI chr 9:80,946,003...80,992,555
Ensembl chr 9:80,946,421...80,991,646
JBrowse link
G NRAS NRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2 OMIM
ClinVar
PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More... NCBI chr20:18,953,273...18,966,002
Ensembl chr20:18,953,883...18,961,931
JBrowse link
G PAX8 paired box 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15785241 NCBI chr14:16,236,074...16,299,650
Ensembl chr14:16,233,378...16,297,365
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:15785241 NCBI chr22:48,262,743...48,407,415
Ensembl chr22:48,275,600...48,407,418
JBrowse link
G PTEN phosphatase and tensin homolog ISO ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2 ClinVar NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146
JBrowse link
G SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 ISO ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2 OMIM
ClinVar
PMID:23539728 PMID:25741868 PMID:28492532 NCBI chr11:59,548,703...59,856,493
Ensembl chr11:59,549,225...59,851,302
JBrowse link
glottis squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WRAP53 WD repeat containing antisense to TP53 disease_progression ISO RGD PMID:28849066 RGD:21081521 NCBI chr16:7,065,531...7,085,590
Ensembl chr16:7,066,333...7,085,625
JBrowse link
head and neck cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCNG2 cyclin G2 ISO mRNA:decreased expression:head and neck (human) RGD PMID:27982046 RGD:151361200 NCBI chr 7:25,657,548...25,667,464
Ensembl chr 7:25,657,441...25,666,254
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 exacerbates ISO mRNA:increased expression:head, neck (human) RGD PMID:31452775 RGD:150520018 NCBI chr 7:22,202,497...22,205,730
Ensembl chr 7:22,202,527...22,204,068
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO DNA:hypermethylation RGD PMID:16721740 PMID:20846153 RGD:14700957 RGD:14700978 NCBI chr26:8,753,236...8,759,378
Ensembl chr26:8,753,327...8,759,384
JBrowse link
G DCDC1 doublecortin domain containing 1 ISO ClinVar Annotator: match by term: Head and neck cancer ClinVar PMID:28492532 PMID:32266149 NCBI chr 1:33,812,925...34,311,269 JBrowse link
G EGFR epidermal growth factor receptor ISO ClinVar Annotator: match by term: Head and neck neoplasm ClinVar PMID:18089823 PMID:18355544 PMID:21172876 PMID:21274259 PMID:23380224 More... NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ISO ClinVar Annotator: match by term: Head and neck neoplasm ClinVar PMID:7668257 PMID:7719344 PMID:8651276 PMID:9677057 PMID:9700203 More... NCBI chr 9:114,234,344...114,354,736
Ensembl chr 9:114,234,250...114,354,704
JBrowse link
G KDM4C lysine demethylase 4C susceptibility ISO DNA:snps:cds, intron:p.N396D (rs2296067), IVS10G>T (rs818912) (human) RGD PMID:19339270 RGD:9587748 NCBI chr12:72,346,194...72,763,040
Ensembl chr12:72,347,071...72,761,666
JBrowse link
G LOC103224275 glutathione S-transferase Mu 1 ISO DNA:hypermethylation RGD PMID:16721740 PMID:20846153 PMID:21133595 RGD:14700957 RGD:14700978 RGD:14700998 NCBI chr20:23,854,969...23,861,634 JBrowse link
G LOC103244924 cyclin-G1 ISO mRNA:decreased expression:head and neck (human) RGD PMID:27982046 RGD:151361200 NCBI chr23:65,709,759...65,716,913
Ensembl chr23:65,709,786...65,714,711
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Head and neck neoplasm ClinVar PMID:15016963 PMID:15254419 PMID:15647370 PMID:15805248 PMID:16906227 More... NCBI chr15:10,218,034...10,304,874
Ensembl chr15:10,218,805...10,294,316
JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein ISO ClinVar Annotator: match by term: Head and neck cancer ClinVar PMID:32266149 NCBI chr16:4,616,325...4,643,791 JBrowse link
G TP53 tumor protein p53 ISO ClinVar Annotator: match by term: Head and neck neoplasm ClinVar PMID:9067756 PMID:11370630 PMID:11782540 PMID:16818505 PMID:17606709 More... NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223
JBrowse link
head and neck squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25275603 NCBI chr21:61,211,044...61,430,691
Ensembl chr21:61,322,748...61,529,274
JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:25275603 NCBI chr 5:14,972,589...15,164,594
Ensembl chr 5:14,972,646...15,164,567
JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25275603 NCBI chr 9:92,826,423...92,902,389
Ensembl chr 9:92,841,818...92,902,265
JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:25275603 NCBI chr 7:36,458,110...36,599,753 JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:11569495 PMID:11853795 PMID:12399961 PMID:12623848 PMID:14745431 More... NCBI chr12:7,258,932...7,435,658
Ensembl chr12:7,256,648...7,312,734
JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO ClinVar Annotator: match by term: Head and neck squamous cell carcinoma ClinVar PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 More... NCBI chr24:82,704,087...82,730,711
Ensembl chr24:82,704,068...82,727,698
JBrowse link
G ANKRD17 ankyrin repeat domain 17 ISO ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:28580594 NCBI chr 7:21,536,241...21,719,320
Ensembl chr 7:21,535,409...21,683,246
JBrowse link
G ATP7B ATPase copper transporting beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:12509969 NCBI chr 3:29,817,712...29,899,302
Ensembl chr 3:29,816,860...29,899,077
JBrowse link
G B2M beta-2-microglobulin ISO ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:26619011 NCBI chr26:38,331,818...38,338,785
Ensembl chr26:38,331,442...38,338,809
JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 exacerbates ISO mRNA:increased expression:head or neck skin (human) RGD PMID:31964418 RGD:153344516 NCBI chr 1:93,721,449...93,746,638 JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 ameliorates ISO mRNA:increased expression:head or neck skin (human) RGD PMID:31964418 RGD:153344516 NCBI chr 1:93,692,239...93,711,905 JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Lip and oral cavity carcinoma | ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:12068308 PMID:12198537 PMID:12447372 PMID:12460918 PMID:12460919 More... NCBI chr21:109,495,525...109,690,261 JBrowse link
G CASP8 caspase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23358896 NCBI chr10:86,888,654...86,944,159
Ensembl chr10:86,916,527...86,943,829
JBrowse link
G CCDC3 coiled-coil domain containing 3 ISO ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:26614431 NCBI chr 9:12,940,629...13,091,520 JBrowse link
G CCNA1 cyclin A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23358896 PMID:29464035 NCBI chr 3:14,979,775...14,992,609
Ensembl chr 3:14,982,392...14,993,562
JBrowse link
G CCNA2 cyclin A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chr 7:69,092,410...69,100,191
Ensembl chr 7:69,093,543...69,099,497
JBrowse link
G CCNB1 cyclin B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chr 4:65,265,798...65,276,465
Ensembl chr 4:65,265,844...65,277,085
JBrowse link
G CCND1 cyclin D1 disease_progression ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:9796972 PMID:26909611 PMID:29464035 RGD:13434911 NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357
JBrowse link
G CCNE1 cyclin E1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chr 6:24,879,923...24,888,985 JBrowse link
G CCNE2 cyclin E2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chr 8:89,846,670...89,863,432
Ensembl chr 8:89,848,077...89,862,037
JBrowse link
G CDC73 cell division cycle 73 exacerbates ISO protein:increased expression:squamous epithelium (human) RGD PMID:26124004 RGD:11065919 NCBI chr25:36,167,482...36,302,918
Ensembl chr25:36,170,134...36,302,812
JBrowse link
G CDK2 cyclin dependent kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chr11:51,905,085...51,910,209
Ensembl chr11:51,905,115...51,909,907
JBrowse link
G CDK4 cyclin dependent kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chr11:53,661,877...53,665,688
Ensembl chr11:53,659,336...53,664,861
JBrowse link
G CDK6 cyclin dependent kinase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chr21:56,167,731...56,403,976
Ensembl chr21:56,170,450...56,393,808
JBrowse link
G CHD4 chromodomain helicase DNA binding protein 4 ISO mRNA:increased expression:head or neck skin (human) RGD PMID:28486105 RGD:153323299 NCBI chr11:6,603,820...6,641,278
Ensembl chr11:6,602,694...6,640,351
JBrowse link
G CLDN1 claudin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33665778 NCBI chr15:84,518,464...84,533,587
Ensembl chr15:84,516,478...84,532,969
JBrowse link
G CNTN4 contactin 4 ISO ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:28595731 NCBI chr22:38,177,481...39,145,568
Ensembl chr22:38,813,569...39,146,953
JBrowse link
G CREBBP CREB binding protein ISO ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:21390126 PMID:21680795 PMID:21796119 PMID:22832583 PMID:23334668 More... NCBI chr 5:3,415,548...3,570,030
Ensembl chr 5:3,415,412...3,540,943
JBrowse link
G CTNNB1 catenin beta 1 ISO ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:9927029 PMID:10192393 PMID:23265383 PMID:25157968 PMID:26619011 More... NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949
JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 treatment ISO DNA:polymorphisms: :CYP2C19*2(human) RGD PMID:19954746 RGD:401901267 NCBI chr 9:87,981,300...88,025,007 JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 treatment ISO DNA:polymorphisms: :CYP2C9*2(human) RGD PMID:19954746 RGD:401901267 NCBI chr 9:88,082,124...88,125,390 JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 treatment ISO DNA:polymorphisms: :CYP2D6*4,CYP2D6*10(human) RGD PMID:19954746 RGD:401901267 NCBI chr19:24,667,207...24,672,580
Ensembl chr19:24,667,282...24,671,513
JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 severity ISO RGD PMID:24556606 RGD:150429746 NCBI chr20:1,298,636...1,451,872
Ensembl chr20:1,299,574...1,359,674
JBrowse link
G DNMT3B DNA methyltransferase 3 beta susceptibility ISO DNA:SNP,haplotype:promoter:-149C>T,-579G>T(human) RGD PMID:18455294 RGD:9589078 NCBI chr 2:37,128,635...37,176,033
Ensembl chr 2:37,146,538...37,174,570
JBrowse link
G DPYD dihydropyrimidine dehydrogenase ISO ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar NCBI chr20:35,376,738...36,215,388
Ensembl chr20:35,377,266...36,215,679
JBrowse link
G EGFR epidermal growth factor receptor ISO ClinVar Annotator: match by term: Head and neck squamous cell carcinoma | ClinVar Annotator: match by term: Lip and oral cavity carcinoma | ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:15118073 PMID:15118125 PMID:15788655 PMID:17177598 PMID:20415598 More... NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239
JBrowse link
G EP300 E1A binding protein p300 ISO ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:26619011 NCBI chr19:23,634,132...23,726,095
Ensembl chr19:23,634,571...23,724,979
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 disease_progression ISO ClinVar Annotator: match by term: Head and neck squamous cell carcinoma RGD
ClinVar
PMID:20604875 PMID:22908275 PMID:26619011 RGD:126790467 NCBI chr16:66,435,488...66,464,993
Ensembl chr16:66,434,251...66,464,952
JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 severity ISO RGD PMID:20604875 RGD:126790467 NCBI chr10:97,099,090...98,281,697 JBrowse link
G FANCB FA complementation group B ISO DNA:hypermethylation:promoter RGD PMID:20332657 RGD:11344903 NCBI chr  X:13,321,304...13,352,368
Ensembl chr  X:13,321,527...13,342,478
JBrowse link
G FANCD2 FA complementation group D2 ISO RGD PMID:20935219 RGD:11344907 NCBI chr22:46,072,797...46,141,107
Ensembl chr22:46,072,761...46,140,713
JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 ISO ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:25741868 PMID:26619011 NCBI chr 7:98,894,261...99,105,955
Ensembl chr 7:98,892,504...99,106,084
JBrowse link
G FGFR3 fibroblast growth factor receptor 3 ISO ClinVar Annotator: match by term: Head and neck squamous cell carcinoma ClinVar PMID:1908846 PMID:7773297 PMID:8589699 PMID:8640234 PMID:8858131 More... NCBI chr27:46,958,444...46,974,032
Ensembl chr27:46,957,254...46,973,392
JBrowse link
G FGFR4 fibroblast growth factor receptor 4 severity ISO DNA:SNP:exon 9: p.G388R (human) RGD PMID:17084840 RGD:150520023 NCBI chr23:79,095,031...79,106,018
Ensembl chr23:79,097,429...79,105,456
JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase ISO ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:28580594 NCBI chr22:21,006,010...22,474,056 JBrowse link
G GRIK2 glutamate ionotropic receptor kainate type subunit 2 ISO ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:26614431 NCBI chr13:71,855,960...72,545,376
Ensembl chr13:71,855,794...72,325,857
JBrowse link
G HOXA5 homeobox A5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22227861 NCBI chr21:31,224,017...31,227,819
Ensembl chr21:31,224,977...31,227,994
JBrowse link
G HOXD10 homeobox D10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22227861 NCBI chr10:61,686,868...61,694,965
Ensembl chr10:61,691,797...61,694,415
JBrowse link
G HOXD11 homeobox D11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22227861 NCBI chr10:61,681,474...61,693,974
Ensembl chr10:61,682,400...61,684,168
JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Head and neck squamous cell carcinoma | ClinVar Annotator: match by term: Lip and oral cavity carcinoma | ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:1904555 PMID:2105486 PMID:3510078 PMID:11150980 PMID:12727991 More... NCBI chr 1:343,613...345,782
Ensembl chr 1:343,506...346,637
JBrowse link
G IFNL3 interferon lambda 3 ISO CTD Direct Evidence: therapeutic CTD PMID:21304406 NCBI chr 6:33,843,140...33,845,444 JBrowse link
G IGF1 insulin like growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30594912 NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308
JBrowse link