Nevi and Melanomas - Ontology Report - Rat Genome Database

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RGD DISEASE ONTOLOGY - ANNOTATIONS

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RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:	Nevi and Melanomas	go back to main search page
Accession:	DOID:9005825	browse the term
Definition:	A collective term for the various types of nevi and melanomas.
Synonyms:	primary_id:	MESH:D018326; RDO:0006092

show annotations for term's descendants Sort by:
Rat (397) Mouse (600) Human (8843) Chinchilla (371) Bonobo (393) Dog (403) Squirrel (378) Pig (388) Green Monkey (383) Naked Mole-rat (371) All
Genes (394) Cell Lines (3)

Nevi and Melanomas

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

BRCA1 associated deubiquitinase 1

CTD Direct Evidence: marker/mechanism

NCBI chr16:6,446,709...6,455,535
Ensembl chr16:6,446,709...6,455,535

amelanotic melanoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

interferon beta 1

CTD Direct Evidence: therapeutic

NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523

Becker Nevus Syndrome

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

actin, beta

ClinVar Annotator: match by term: BECKER NEVUS, ISOLATED, SOMATIC, MOSAIC

PMID:28347698 PMID:32170967

NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877

Blue Rubber Bleb Nevus Syndrome

term browser

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Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

glomulin, FKBP associated protein

ClinVar Annotator: match by term: Blue rubber bleb nevus

NCBI chr14:2,187,144...2,231,295
Ensembl chr14:2,187,642...2,230,420

G

TEK receptor tyrosine kinase

ClinVar Annotator: match by term: Blue rubber bleb nevus

PMID:10369874 PMID:20301733 PMID:25741868

NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804

CLOVES syndrome

term browser

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Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

G protein subunit alpha 11

ClinVar Annotator: match by term: Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi

PMID:25741868 PMID:27476652

NCBI chr 7:8,163,520...8,177,863
Ensembl chr 7:8,162,750...8,179,812

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

ClinVar Annotator: match by term: CLOVE SYNDROME | ClinVar Annotator: match by term: CLOVES syndrome | ClinVar Annotator: match by term: CONGENITAL LIPOMATOUS OVERGROWTH, VASCULAR MALFORMATIONS, EPIDERMAL NEVI, AND SKELETAL/SPINAL ABNORMALITIES | ClinVar Annotator: match by term: Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi
OMIM:612918
CTD Direct Evidence: marker/mechanism
DNA: missense mutations: exon :p.H1047R, p.H1047L

OMIM
ClinVar
MouseDO
CTD
RGD

PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More...

NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032

G

phosphoinositide-3-kinase regulatory subunit 1

ClinVar Annotator: match by term: CLOVES syndrome

PMID:25741868 PMID:34040190

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

dysplastic nevus syndrome

term browser

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Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

B-Raf proto-oncogene, serine/threonine kinase

ClinVar Annotator: match by term: B-K MOLE SYNDROME

PMID:16439621 PMID:16474404 PMID:17366577 PMID:17551924 PMID:17703371 More...

NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463

G

cyclin-dependent kinase inhibitor 2A

DNA:missense mutation:exon:p.P48L (human)

RGD

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

G

protection of telomeres 1

ClinVar Annotator: match by term: B-K MOLE SYNDROME

PMID:24686846 PMID:25741868 PMID:26467025 PMID:28492532 PMID:30451293 More...

NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042

G

phosphatase and tensin homolog

ClinVar Annotator: match by term: B-K MOLE SYNDROME

PMID:24033266 PMID:24055113 PMID:25741868 PMID:25980754 PMID:28492532 More...

NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838

G

serine/threonine kinase 11

ClinVar Annotator: match by term: B-K MOLE SYNDROME

PMID:25741868 PMID:26467025 PMID:26580448 PMID:28492532 PMID:29368341 More...

NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315

epidermal nevus

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

fibroblast growth factor receptor 3

ClinVar Annotator: match by term: Epidermal nevus | ClinVar Annotator: match by term: NEVUS, KERATINOCYTIC, NONEPIDERMOLYTIC
ClinVar Annotator: match by term: Epidermal nevus | ClinVar Annotator: match by term: NEVUS, KERATINOCYTIC, NONEPIDERMOLYTIC | ClinVar Annotator: match by term: Woolly hair nevus
CTD Direct Evidence: marker/mechanism

OMIM
ClinVar
CTD

PMID:1908846 PMID:7647778 PMID:7649548 PMID:7670477 PMID:7702086 More...

NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341

G

HRas proto-oncogene, GTPase

ClinVar Annotator: match by term: Epidermal nevus | ClinVar Annotator: match by term: NEVUS, KERATINOCYTIC, NONEPIDERMOLYTIC | ClinVar Annotator: match by term: Nevus sebaceous | ClinVar Annotator: match by term: Woolly hair nevus
CTD Direct Evidence: marker/mechanism

OMIM
ClinVar
CTD

PMID:2105486 PMID:2999610 PMID:3537694 PMID:6092966 PMID:6330729 More...

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

G

KRAS proto-oncogene, GTPase

ClinVar Annotator: match by term: NEVUS, KERATINOCYTIC, NONEPIDERMOLYTIC | ClinVar Annotator: match by term: Nevus sebaceous

PMID:2278970 PMID:2547513 PMID:3122217 PMID:3627975 PMID:7773929 More...

NCBI chr 4:178,185,418...178,218,484

G

leucine rich repeat containing 56

ClinVar Annotator: match by term: Epidermal nevus | ClinVar Annotator: match by term: NEVUS, KERATINOCYTIC, NONEPIDERMOLYTIC | ClinVar Annotator: match by term: Nevus sebaceous
ClinVar Annotator: match by term: Epidermal nevus | ClinVar Annotator: match by term: NEVUS, KERATINOCYTIC, NONEPIDERMOLYTIC | ClinVar Annotator: match by term: Nevus sebaceous | ClinVar Annotator: match by term: Woolly hair nevus

PMID:2105486 PMID:2999610 PMID:3537694 PMID:6092966 PMID:6330729 More...

NCBI chr 1:196,299,843...196,315,170
Ensembl chr 1:196,299,846...196,315,172

G

NRAS proto-oncogene, GTPase

ClinVar Annotator: match by term: Epidermal nevus | ClinVar Annotator: match by term: NEVUS, KERATINOCYTIC, NONEPIDERMOLYTIC
CTD Direct Evidence: marker/mechanism

OMIM
ClinVar
CTD

PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More...

NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

ClinVar Annotator: match by term: Epidermal nevus | ClinVar Annotator: match by term: NEVUS, KERATINOCYTIC, NONEPIDERMOLYTIC
CTD Direct Evidence: marker/mechanism

OMIM
ClinVar
CTD

PMID:15016963 PMID:15254419 PMID:15520168 PMID:15647370 PMID:15805248 More...

NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032

Experimental Melanoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acyl-CoA synthetase short-chain family member 1

treatment

RGD

NCBI chr 3:139,450,383...139,500,325
Ensembl chr 3:139,450,383...139,500,325

G

acyl-CoA synthetase short-chain family member 2

treatment

RGD

NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675

G

ANTXR cell adhesion molecule 1

treatment

RGD

PMID:19622764 PMID:19609240

RGD:9684925, RGD:9684939

NCBI chr 4:119,590,770...119,778,232
Ensembl chr 4:119,590,771...119,778,232

G

B-Raf proto-oncogene, serine/threonine kinase

CTD Direct Evidence: marker/mechanism

PMID:29179997 PMID:29438700

NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463

G

calreticulin

CTD Direct Evidence: therapeutic

NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414

G

C-C motif chemokine ligand 20

treatment

RGD

NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629

G

cytotoxic T-lymphocyte-associated protein 4

treatment

RGD

NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963

G

early growth response 1

mRNA, protein:increased expression:salivary gland (mouse)

RGD

NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766

G

estrogen receptor 2

severity

RGD

NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919

G

hepatocyte growth factor

RGD

NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409

G

interferon beta 1

CTD Direct Evidence: therapeutic

NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523

G

inhibitor of nuclear factor kappa B kinase subunit beta

RGD

NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250

G

interleukin 18

treatment

RGD

PMID:12230493 PMID:17411412

RGD:8655870, RGD:8655901

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

G

interleukin 1 alpha

treatment

RGD

NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822

G

interleukin 1 beta

RGD

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 2

RGD

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

lysine demethylase 1A

CTD Direct Evidence: marker/mechanism

NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319

G

lysine demethylase 4C

CTD Direct Evidence: marker/mechanism

NCBI chr 5:88,100,710...88,306,821
Ensembl chr 5:88,100,733...88,306,818

G

melanocortin 1 receptor

RGD

NCBI chr19:51,452,448...51,455,375
Ensembl chr19:51,453,239...51,454,192

G

programmed cell death 1

treatment

RGD

NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937

G

phosphatase and tensin homolog

CTD Direct Evidence: marker/mechanism

NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838

G

paxillin

CTD Direct Evidence: marker/mechanism

NCBI chr12:41,060,791...41,107,952
Ensembl chr12:41,060,791...41,107,931

G

telomerase reverse transcriptase

treatment

RGD

NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561

familial melanoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ArfGAP with GTPase domain, ankyrin repeat and PH domain 2

ClinVar Annotator: match by term: Familial melanoma

NCBI chr 7:62,897,282...62,914,295
Ensembl chr 7:62,897,282...62,914,295

G

Rho GTPase activating protein 9

ClinVar Annotator: match by term: Familial melanoma

NCBI chr 7:63,148,573...63,157,025
Ensembl chr 7:63,148,900...63,157,524

G

Rho guanine nucleotide exchange factor 25

ClinVar Annotator: match by term: Familial melanoma

NCBI chr 7:63,005,938...63,013,325
Ensembl chr 7:63,005,940...63,013,719

G

beta-1,4-N-acetyl-galactosaminyl transferase 1

ClinVar Annotator: match by term: Familial melanoma

NCBI chr 7:62,988,429...62,996,190
Ensembl chr 7:62,988,930...62,996,190

G

BRCA1 associated deubiquitinase 1

ClinVar Annotator: match by term: Familial melanoma

PMID:21874000 PMID:23684012 PMID:25741868 PMID:28492532

NCBI chr16:6,446,709...6,455,535
Ensembl chr16:6,446,709...6,455,535

G

B-Raf proto-oncogene, serine/threonine kinase

ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 1
ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 1 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10

PMID:2500657 PMID:16439621 PMID:16474404 PMID:17366577 PMID:17551924 More...

NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463

G

cyclin-dependent kinase 4

ClinVar Annotator: match by term: Cutaneous Malignant Melanoma, Dominant | ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 3 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5
ClinVar Annotator: match by term: Cutaneous Malignant Melanoma, Dominant | ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: MELANOMA AND RENAL CELL CARCINOMA, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 3
ClinVar Annotator: match by term: Cutaneous Malignant Melanoma, Dominant | ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Hereditary cutaneous melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 3 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5
ClinVar Annotator: match by term: Cutaneous Malignant Melanoma, Dominant | ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 2 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 3
ClinVar Annotator: match by term: Cutaneous Malignant Melanoma, Dominant | ClinVar Annotator: match by term: Cutaneous malignant melanoma 5 | ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 3 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5
ClinVar Annotator: match by term: Cutaneous Malignant Melanoma, Dominant | ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 2 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 3 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5

PMID:5377176 PMID:7652577 PMID:8528263 PMID:8968104 PMID:9228064 More...

NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403

G

cyclin-dependent kinase inhibitor 2A

ClinVar Annotator: match by term: Cutaneous malignant melanoma 9 | ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Hereditary cutaneous melanoma | ClinVar Annotator: match by term: MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 9 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 1 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 2 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 3 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5
ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Hereditary cutaneous melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 1 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 2
ClinVar Annotator: match by term: Cutaneous malignant melanoma 9 | ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Hereditary cutaneous melanoma | ClinVar Annotator: match by term: MELANOMA AND RENAL CELL CARCINOMA, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 1 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 2 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 3 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 9
ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Hereditary cutaneous melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 2 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 3 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5
ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Hereditary cutaneous melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 1 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 2 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5
ClinVar Annotator: match by term: Cutaneous Malignant Melanoma, Dominant | ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Hereditary cutaneous melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 2
ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Hereditary cutaneous melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 2 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5
ClinVar Annotator: match by term: Cutaneous malignant melanoma 5 | ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Hereditary cutaneous melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 2 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 3 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5
ClinVar Annotator: match by term: Cutaneous Malignant Melanoma, Dominant | ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Hereditary cutaneous melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 2 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 3 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5

PMID:539244 PMID:649266 PMID:865368 PMID:1038976 PMID:2319082 More...

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

G

cyclin-dependent kinase inhibitor 2B

ClinVar Annotator: match by term: Familial melanoma

PMID:9622062 PMID:28492532

NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050

G

cytochrome P450, family 27, subfamily b, polypeptide 1

ClinVar Annotator: match by term: Familial melanoma

NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241

G

dynactin subunit 2

ClinVar Annotator: match by term: Familial melanoma

NCBI chr 7:63,092,061...63,107,560
Ensembl chr 7:63,092,057...63,108,543

G

DNA-damage inducible transcript 3

ClinVar Annotator: match by term: Familial melanoma

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

dynein, axonemal, heavy chain 1

ClinVar Annotator: match by term: Familial melanoma

PMID:21874000 PMID:23684012 PMID:25741868 PMID:28492532

NCBI chr16:6,455,514...6,517,103
Ensembl chr16:6,456,002...6,518,350

G

deltex E3 ubiquitin ligase 3

ClinVar Annotator: match by term: Familial melanoma

NCBI chr 7:63,013,769...63,018,431
Ensembl chr 7:63,013,371...63,018,522

G

EEF1A lysine methyltransferase 3

ClinVar Annotator: match by term: Familial melanoma

NCBI chr 7:62,853,304...62,864,558
Ensembl chr 7:62,854,899...62,864,617

G

FA complementation group A

ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5

NCBI chr19:51,304,126...51,362,586
Ensembl chr19:51,304,021...51,362,527

G

GLI family zinc finger 1

ClinVar Annotator: match by term: Familial melanoma

NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251

G

inhibin subunit beta C

ClinVar Annotator: match by term: Familial melanoma

NCBI chr 7:63,184,141...63,197,630
Ensembl chr 7:63,184,142...63,197,630

G

inhibin subunit beta E

ClinVar Annotator: match by term: Familial melanoma

NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172

G

kinesin family member 5A

ClinVar Annotator: match by term: Familial melanoma

NCBI chr 7:63,051,894...63,089,024
Ensembl chr 7:63,049,424...63,092,858

G

kinesin light chain 1

ClinVar Annotator: match by term: Cutaneous malignant melanoma 6

PMID:11059748 PMID:28492532

NCBI chr 6:130,823,416...130,866,729
Ensembl chr 6:130,823,419...130,867,031

G

LDL receptor related protein 1

ClinVar Annotator: match by term: Familial melanoma

NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910

G

membrane associated ring-CH-type finger 9

ClinVar Annotator: match by term: Familial melanoma

NCBI chr 7:62,879,017...62,882,495
Ensembl chr 7:62,879,018...62,882,495

G

methionyl-tRNA synthetase 1

ClinVar Annotator: match by term: Familial melanoma

NCBI chr 7:63,121,142...63,138,550
Ensembl chr 7:63,121,142...63,138,495

G

methyl-CpG binding domain protein 6

ClinVar Annotator: match by term: Familial melanoma

NCBI chr 7:63,107,562...63,115,841
Ensembl chr 7:63,107,562...63,113,274

G

melanocortin 1 receptor

ClinVar Annotator: match by term: Cutaneous malignant melanoma 5 | ClinVar Annotator: match by term: Cutaneous malignant melanoma 9 | ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: MELANOMA AND RENAL CELL CARCINOMA, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5
ClinVar Annotator: match by term: Cutaneous malignant melanoma 5 | ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 2 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 3 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5
ClinVar Annotator: match by term: Cutaneous malignant melanoma 5 | ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5

PMID:7581459 PMID:8605020 PMID:8894704 PMID:8944016 PMID:8990005 More...

NCBI chr19:51,452,448...51,455,375
Ensembl chr19:51,453,239...51,454,192

G

methyltransferase 1, tRNA methylguanosine

ClinVar Annotator: match by term: Familial melanoma

NCBI chr 7:62,864,860...62,869,202
Ensembl chr 7:62,864,853...62,869,202

G

melanocyte inducing transcription factor

ClinVar Annotator: match by term: MELANOMA AND RENAL CELL CARCINOMA, SUSCEPTIBILITY TO
ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: MELANOMA AND RENAL CELL CARCINOMA, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 8
ClinVar Annotator: match by term: MELANOMA AND RENAL CELL CARCINOMA, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 8

PMID:2440678 PMID:8589691 PMID:8659547 PMID:9536098 PMID:10587587 More...

NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145

G

NDUFA4, mitochondrial complex associated like 2

ClinVar Annotator: match by term: Familial melanoma

NCBI chr 7:63,351,021...63,359,010
Ensembl chr 7:63,356,883...63,359,010

G

neurexophilin 4

ClinVar Annotator: match by term: Familial melanoma

NCBI chr 7:63,367,758...63,376,579
Ensembl chr 7:63,367,761...63,376,579

G

OS9, endoplasmic reticulum lectin

ClinVar Annotator: match by term: Familial melanoma

NCBI chr 7:62,915,498...62,957,591
Ensembl chr 7:62,915,515...62,943,745

G

phosphatidylinositol-5-phosphate 4-kinase type 2 gamma

ClinVar Annotator: match by term: Familial melanoma

NCBI chr 7:63,020,004...63,035,086
Ensembl chr 7:63,020,000...63,035,078

G

protection of telomeres 1

ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 3 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5
ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 1 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 3 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5
ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Hereditary cutaneous melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 1 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 3 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 8 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 9
ClinVar Annotator: match by term: Cutaneous malignant melanoma 9 | ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: MELANOMA AND RENAL CELL CARCINOMA, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 1 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 2 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 3 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 8
ClinVar Annotator: match by term: Cutaneous malignant melanoma 5 | ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 1 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 2 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 8
ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Hereditary cutaneous melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 1 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5
ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 1 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5
ClinVar Annotator: match by term: Cutaneous Malignant Melanoma, Dominant | ClinVar Annotator: match by term: Cutaneous malignant melanoma 5 | ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 3 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5
ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 2 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 3 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 8
ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5
ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 2 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 6
ClinVar Annotator: match by term: Cutaneous malignant melanoma 5 | ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5

PMID:9536098 PMID:16199547 PMID:17576681 PMID:19461895 PMID:19763152 More...

NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042

G

phosphatase and tensin homolog

ClinVar Annotator: match by term: MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 1

PMID:24033266 PMID:24055113 PMID:25741868 PMID:25980754 PMID:28492532 More...

NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838

G

R3H domain containing 2

ClinVar Annotator: match by term: Familial melanoma

NCBI chr 7:63,212,519...63,340,574
Ensembl chr 7:63,232,346...63,340,540

G

serine hydroxymethyltransferase 2

ClinVar Annotator: match by term: Familial melanoma

NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236

G

spire-type actin nucleation factor 2

ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5

NCBI chr19:51,373,368...51,411,920
Ensembl chr19:51,373,228...51,411,920

G

SH3 and cysteine rich domain 3

ClinVar Annotator: match by term: Familial melanoma

NCBI chr 7:63,343,078...63,350,590
Ensembl chr 7:63,343,186...63,350,589

G

serine/threonine kinase 11

ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 1 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10
ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: MELANOMA AND RENAL CELL CARCINOMA, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 1 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10

PMID:9536098 PMID:9887330 PMID:10201537 PMID:10208439 PMID:10676634 More...

NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315

G

transcription factor 25

ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5

NCBI chr19:51,415,341...51,449,725
Ensembl chr19:51,415,543...51,449,723

G

telomerase reverse transcriptase

ClinVar Annotator: match by term: Cutaneous malignant melanoma 9 | ClinVar Annotator: match by term: MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 9 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 1 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 3 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 9
ClinVar Annotator: match by term: Cutaneous malignant melanoma 9 | ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 9 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 1 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 9
ClinVar Annotator: match by term: Cutaneous malignant melanoma 9 | ClinVar Annotator: match by term: MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 9 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 1 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 9

PMID:15814878 PMID:19561322 PMID:20301779 PMID:20871597 PMID:21436073 More...

NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561

G

tumor protein p53

ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5
ClinVar Annotator: match by term: Familial melanoma

PMID:12826609 PMID:25741868 PMID:28492532 PMID:29979965 PMID:30224644

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

G

Ts translation elongation factor, mitochondrial

ClinVar Annotator: match by term: Familial melanoma

NCBI chr 7:62,828,997...62,864,784
Ensembl chr 7:62,845,488...62,864,769

G

tetraspanin 31

ClinVar Annotator: match by term: Cutaneous Malignant Melanoma, Dominant | ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 3 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5
ClinVar Annotator: match by term: Cutaneous Malignant Melanoma, Dominant | ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 3
ClinVar Annotator: match by term: Cutaneous Malignant Melanoma, Dominant | ClinVar Annotator: match by term: Familial melanoma | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 3 | ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 5

PMID:9536098 PMID:17576681 PMID:20668451 PMID:21520333 PMID:23718828 More...

NCBI chr 7:62,889,552...62,892,428
Ensembl chr 7:62,889,552...62,898,388

G

tyrosinase

ClinVar Annotator: match by term: Melanoma, cutaneous malignant, susceptibility to, 10

PMID:666627 PMID:1429711 PMID:1820207 PMID:7704033 PMID:9158138 More...

NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207

G

X-ray repair cross complementing 3

ClinVar Annotator: match by term: Cutaneous malignant melanoma 6

PMID:11059748 PMID:28492532

NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444

large congenital melanocytic nevus

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

HRas proto-oncogene, GTPase

ClinVar Annotator: match by term: Congenital giant melanocytic nevus | ClinVar Annotator: match by term: Large congenital melanocytic nevus
CTD Direct Evidence: marker/mechanism

OMIM
ClinVar
CTD

PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 PMID:16835863 More...

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

G

leucine rich repeat containing 56

ClinVar Annotator: match by term: Congenital giant melanocytic nevus | ClinVar Annotator: match by term: Large congenital melanocytic nevus | ClinVar Annotator: match by term: MELANOCYTIC NEVUS SYNDROME, CONGENITAL, SOMATIC

PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 PMID:16835863 More...

NCBI chr 1:196,299,843...196,315,170
Ensembl chr 1:196,299,846...196,315,172

G

NRAS proto-oncogene, GTPase

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Congenital giant melanocytic nevus | ClinVar Annotator: match by term: Large congenital melanocytic nevus

OMIM
CTD
ClinVar

PMID:1654209 PMID:2278970 PMID:2674680 PMID:3102434 PMID:3122217 More...

NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626

linear nevus sebaceous syndrome

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

HRas proto-oncogene, GTPase

ClinVar Annotator: match by term: Linear nevus sebaceous | ClinVar Annotator: match by term: Linear nevus sebaceous syndrome | ClinVar Annotator: match by term: Organoid nevus phakomatosis
DNA:mutation:cds:c.37G>C(p.G13R)(human)
CTD Direct Evidence: marker/mechanism

OMIM
ClinVar
CTD
RGD

PMID:12835555 PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 More...

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

G

KRAS proto-oncogene, GTPase

ClinVar Annotator: match by term: Linear nevus sebaceous
CTD Direct Evidence: marker/mechanism

OMIM
ClinVar
CTD

PMID:2278970 PMID:3122217 PMID:7773929 PMID:8439212 PMID:12110640 More...

NCBI chr 4:178,185,418...178,218,484

G

leucine rich repeat containing 56

ClinVar Annotator: match by term: Linear nevus sebaceous | ClinVar Annotator: match by term: Linear nevus sebaceous syndrome | ClinVar Annotator: match by term: Organoid nevus phakomatosis

PMID:12835555 PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 More...

NCBI chr 1:196,299,843...196,315,170
Ensembl chr 1:196,299,846...196,315,172

G

NRAS proto-oncogene, GTPase

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Linear nevus sebaceous

OMIM
CTD
ClinVar

PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More...

NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626

melanoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily B member 5

CTD Direct Evidence: marker/mechanism

NCBI chr 6:139,836,528...139,932,830
Ensembl chr 6:139,835,949...139,932,830

G

alkaline ceramidase 3

CTD Direct Evidence: marker/mechanism

NCBI chr 1:152,504,180...152,606,596
Ensembl chr 1:152,504,186...152,606,591

G

ADAM metallopeptidase with thrombospondin type 1 motif, 20

CTD Direct Evidence: marker/mechanism

NCBI chr 7:125,396,227...125,528,020
Ensembl chr 7:125,397,734...125,527,777

G

advanced glycosylation end product-specific receptor

treatment

RGD

NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078

G

aldo-keto reductase family 1 member B10

CTD Direct Evidence: marker/mechanism

NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852

G

AKT serine/threonine kinase 1

ClinVar Annotator: match by term: Malignant melanoma, somatic | ClinVar Annotator: match by term: Melanoma

PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 More...

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

aldehyde dehydrogenase 1 family, member A1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961

G

aldehyde dehydrogenase 1 family, member A3

CTD Direct Evidence: marker/mechanism

NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436

G

adhesion molecule with Ig like domain 2

treatment

RGD

NCBI chr 7:128,391,493...128,394,589
Ensembl chr 7:128,390,412...128,394,695

G

apurinic/apyrimidinic endodeoxyribonuclease 1

CTD Direct Evidence: marker/mechanism

NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785

G

ARF like GTPase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:203,434,129...203,446,156
Ensembl chr 1:203,434,129...203,446,119

G

ARF like GTPase 5B

CTD Direct Evidence: marker/mechanism

NCBI chr17:77,955,864...77,979,895
Ensembl chr17:77,955,818...77,979,854

G

aryl hydrocarbon receptor nuclear translocator

CTD Direct Evidence: marker/mechanism

NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580

G

actin related protein 2/3 complex, subunit 2

protein:increased expression:nevus (human)

RGD

NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471

G

anti-silencing function 1A histone chaperone

CTD Direct Evidence: marker/mechanism

NCBI chr20:32,893,962...32,908,808
Ensembl chr20:32,893,573...32,908,808

G

agouti signaling protein

CTD Direct Evidence: marker/mechanism

PMID:18488027 PMID:18641652 PMID:21983785

NCBI chr 3:143,473,584...143,561,170
Ensembl chr 3:143,555,696...143,561,171

G

argininosuccinate synthase 1

RGD

NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903

G

ATM serine/threonine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437

G

ATRX, chromatin remodeler

disease_progression

protein:decreased expression:skin:

RGD

NCBI chr X:70,850,981...70,997,330
Ensembl chr X:70,850,981...70,997,330

G

aurora kinase A

CTD Direct Evidence: marker/mechanism

NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390

G

beta-2 microglobulin

ClinVar Annotator: match by term: Malignant melanoma, somatic

NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766

G

basic leucine zipper ATF-like transcription factor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:203,467,291...203,479,428
Ensembl chr 1:203,468,097...203,475,889

G

BCL2, apoptosis regulator

severity

protein:increased expression:lymph node (human)

RGD

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

Bcl2-like 1

disease_progression

protein:increased expression:skin, subcutaneous tissue (human)

RGD

NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479

G

Bcl2 like 12

ClinVar Annotator: match by term: Malignant melanoma, somatic

NCBI chr 1:95,472,272...95,480,991
Ensembl chr 1:95,472,272...95,480,991

G

basophilic leukemia expressed protein BLES03

CTD Direct Evidence: marker/mechanism

NCBI chr 1:202,734,555...202,736,809
Ensembl chr 1:202,734,555...202,736,804

G

bone morphogenetic protein 4

susceptibility

DNA:SNP:cds:6007C>T (rs17563)(human)

RGD

NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306

G

B-Raf proto-oncogene, serine/threonine kinase

treatment
onset

ClinVar Annotator: match by term: MELANOMA, MALIGNANT | ClinVar Annotator: match by term: Malignant melanoma, somatic | ClinVar Annotator: match by term: Melanoma
associated with Neoplasm Metastasis; DNA:mutation:multiple (human)
CTD Direct Evidence: marker/mechanism
DNA:mutations: :

ClinVar
MouseDO
CTD
RGD

PMID:2493360 PMID:2872605 PMID:8042262 PMID:12068308 PMID:12198537 More...

RGD:1580103, RGD:151660349, RGD:11567267, RGD:11567259

NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463

G

BRCA2, DNA repair associated

susceptibility

DNA:polymorphism:cds:p.N991D(human)
ClinVar Annotator: match by term: Melanoma

PMID:25741868 PMID:28492532 PMID:31911673 PMID:18024013

NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567

G

bromodomain containing 2

protein:mRNA:skin:

RGD

NCBI chr20:4,727,078...4,735,389
Ensembl chr20:4,728,151...4,735,388

G

bromodomain containing 4

protein:mRNA:skin:

RGD

NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539

G

basigin

CTD Direct Evidence: marker/mechanism

NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387

G

basic leucine zipper and W2 domains 1

CTD Direct Evidence: marker/mechanism

NCBI chr 9:59,930,672...59,944,468
Ensembl chr 9:59,930,744...59,944,430

G

complement C3

treatment

RGD

NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429

G

calpain 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177

G

caspase 8

CTD Direct Evidence: marker/mechanism

PMID:18563783 PMID:21983787

NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542

G

catalase

protein:increased activity:melanocyte:
protein:increased activity:multiple:

RGD

PMID:9758419 PMID:15224238

RGD:9479151, RGD:9479742

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

caveolin 1

disease_progression

RGD

NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705

G

cystathionine beta synthase

CTD Direct Evidence: marker/mechanism

NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764

G

coiled-coil domain containing 63

CTD Direct Evidence: marker/mechanism

NCBI chr12:34,424,388...34,453,080
Ensembl chr12:34,424,344...34,453,085

G

CD274 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450

G

CD40 molecule

treatment

RGD

PMID:22421945 PMID:17327609

RGD:11522740, RGD:11522745

NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534

G

cyclin dependent kinase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403

G

cyclin-dependent kinase 4

ClinVar Annotator: match by term: Melanoma

PMID:5377176 PMID:7652577 PMID:8528263 PMID:8968104 PMID:9228064 More...

NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403

G

cyclin-dependent kinase inhibitor 1A

protein:increased expression:skin

RGD

PMID:22311377 PMID:9194578

RGD:8662421, RGD:8662817

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1C

CTD Direct Evidence: marker/mechanism

NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048

G

cyclin-dependent kinase inhibitor 2A

susceptibility

DNA:point mutation, insertion:exon
ClinVar Annotator: match by term: Malignant melanoma, somatic | ClinVar Annotator: match by term: Melanoma
CTD Direct Evidence: marker/mechanism

ClinVar
CTD
RGD

PMID:7566978 PMID:7647780 PMID:7666917 PMID:7718873 PMID:7777061 More...

RGD:1600812, RGD:8552300

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

G

checkpoint kinase 2

ClinVar Annotator: match by term: Melanoma

PMID:12533788 PMID:15087378 PMID:15095295 PMID:15492928 PMID:15810020 More...

NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286

G

chitinase 3 like 1

severity

protein:increased secretion:serum (human)

RGD

NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787

G

chloride nucleotide-sensitive channel 1A

CTD Direct Evidence: marker/mechanism

NCBI chr 1:152,019,369...152,039,670
Ensembl chr 1:152,019,378...152,039,661

G

clusterin

CTD Direct Evidence: therapeutic

NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315

G

cyclin and CBS domain divalent metal cation transport mediator 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:242,296,367...242,354,957
Ensembl chr 1:242,296,422...242,353,513

G

collagen type II alpha 1 chain

CTD Direct Evidence: marker/mechanism

NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546

G

ceruloplasmin

CTD Direct Evidence: marker/mechanism

NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075

G

carnitine palmitoyltransferase 1c

CTD Direct Evidence: marker/mechanism

NCBI chr 1:95,442,814...95,457,347
Ensembl chr 1:95,442,817...95,457,342

G

CREB binding protein

ClinVar Annotator: match by term: Malignant melanoma, somatic

PMID:21390126 PMID:21680795 PMID:21796119 PMID:22832583 PMID:23334668 More...

NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888

G

crooked neck pre-mRNA splicing factor 1

ClinVar Annotator: match by term: Malignant melanoma, somatic

NCBI chr 3:133,338,593...133,354,329
Ensembl chr 3:133,337,039...133,354,302
Ensembl chr 6:133,337,039...133,354,302

G

crystallin beta-gamma domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr20:47,425,030...47,496,918
Ensembl chr20:47,426,183...47,621,392

G

colony stimulating factor 2

CTD Direct Evidence: therapeutic

NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199

G

colony stimulating factor 3

CTD Direct Evidence: therapeutic

PMID:16120623 PMID:16260693

NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603

G

cystatin E/M

CTD Direct Evidence: marker/mechanism

NCBI chr 1:202,655,322...202,657,030
Ensembl chr 1:202,655,322...202,657,030

G

cystathionine gamma-lyase

CTD Direct Evidence: marker/mechanism

NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234

G

cytotoxic T-lymphocyte-associated protein 4

treatment

DNA:SNPs: :-11577G>A,rs3087243(human)
CTD Direct Evidence: therapeutic

CTD
RGD

PMID:21802280 PMID:23641913

NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963

G

catenin beta 1

ClinVar Annotator: match by term: Malignant melanoma, somatic | ClinVar Annotator: match by term: Melanoma

PMID:9065402 PMID:9065403 PMID:9294210 PMID:9500465 PMID:9927029 More...

NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111

G

cubilin

CTD Direct Evidence: marker/mechanism

NCBI chr17:76,385,046...76,593,133
Ensembl chr17:76,385,060...76,593,231

G

cullin 3

CTD Direct Evidence: marker/mechanism

NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462

G

cytochrome P450, family 1, subfamily b, polypeptide 1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917

G

discoidin, CUB and LCCL domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr20:31,618,556...31,711,697
Ensembl chr20:31,618,542...31,711,692

G

DCC netrin 1 receptor

CTD Direct Evidence: marker/mechanism

NCBI chr18:64,868,987...65,972,783
Ensembl chr18:64,873,898...65,972,740

G

DNA-damage-inducible transcript 4-like

CTD Direct Evidence: marker/mechanism

NCBI chr 2:226,128,273...226,131,044
Ensembl chr 2:226,128,276...226,131,375

G

discoidin domain receptor tyrosine kinase 2

ameliorates

DNA:deletion:exons:

RGD

NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363

G

discs large MAGUK scaffold protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:144,451,653...146,503,949
Ensembl chr 1:144,451,472...146,499,475

G

DnaJ heat shock protein family (Hsp40) member C1

CTD Direct Evidence: marker/mechanism

NCBI chr17:80,955,209...81,112,025
Ensembl chr17:80,955,237...81,111,988

G

DnaJ heat shock protein family (Hsp40) member C15

CTD Direct Evidence: marker/mechanism

NCBI chr15:53,182,060...53,249,675
Ensembl chr15:53,184,855...53,249,675

G

DNA methyltransferase 3 alpha

ClinVar Annotator: match by term: Melanoma

PMID:24614070 PMID:28475857 PMID:28492532 PMID:29900417

NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687

G

Dr1 associated protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:202,731,775...202,734,468
Ensembl chr 1:202,731,788...202,734,425

G

desmocollin 1

CTD Direct Evidence: marker/mechanism

NCBI chr18:11,499,936...11,556,801
Ensembl chr18:11,502,003...11,528,494

G

E2F transcription factor 1

CTD Direct Evidence: marker/mechanism|therapeutic

PMID:15574415 PMID:16827129

NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361

G

ethylmalonyl-CoA decarboxylase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:28,476,354...28,507,173
Ensembl chr 1:28,476,200...28,507,319

G

ectodysplasin-A

CTD Direct Evidence: marker/mechanism

NCBI chr X:65,078,454...65,480,172
Ensembl chr X:65,078,673...65,480,172

G

euchromatic histone lysine methyltransferase 2

disease_progression

RGD

NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547

G

eukaryotic translation initiation factor 1A domain containing

CTD Direct Evidence: marker/mechanism

NCBI chr 1:202,674,362...202,679,662
Ensembl chr 1:202,674,185...202,679,658

G

elastin

disease_progression

associated with Nevus, Pigmented;

RGD

PMID:11979070 PMID:19032378

RGD:9585752, RGD:9585768

NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928

G

endoglin

treatment

RGD

NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230

G

E1A binding protein p300

CTD Direct Evidence: marker/mechanism

NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088

G

erythrocyte membrane protein band 4.1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:144,110,010...144,264,037
Ensembl chr 5:144,111,906...144,237,821

G

epoxide hydrolase 3

CTD Direct Evidence: marker/mechanism

NCBI chr 7:11,206,812...11,212,122
Ensembl chr 7:11,206,812...11,212,122

G

erythropoietin

CTD Direct Evidence: marker/mechanism

NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946

G

erythropoietin receptor

CTD Direct Evidence: marker/mechanism

NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257

G

erb-b2 receptor tyrosine kinase 2

ClinVar Annotator: match by term: Malignant melanoma, somatic

PMID:18413839 PMID:22046346 PMID:23220880 PMID:25157968 PMID:26619011

NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078

G

erb-b2 receptor tyrosine kinase 4

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Melanoma

NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595

G

ERCC excision repair 1, endonuclease non-catalytic subunit

CTD Direct Evidence: marker/mechanism

NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963

G

ERCC excision repair 2, TFIIH core complex helicase subunit

disease_progression

DNA:polymorphism:exon:p.K751Q(human)

RGD

NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102

G

ERCC excision repair 5, endonuclease

disease_progression

DNA:polymorphism:exon:p.D1104H(human)

RGD

NCBI chr 9:46,309,477...46,354,478
Ensembl chr 9:46,309,389...46,354,472

G

estrogen receptor 1

severity

RGD

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

estrogen receptor 2

severity

RGD

NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919

G

F2R like trypsin receptor 1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226

G

Fas cell surface death receptor

susceptibility

DNA:polymorphisms:promoter:-1377A>G,-670A>G(human)

RGD

NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591

G

Fas ligand

susceptibility

CTD Direct Evidence: therapeutic
DNA:polymorphisms,haplotype:promoter:-844C>T,IVS2nt-124A>G(human)

CTD
RGD

PMID:16487513 PMID:16538172

NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215

G

fatty acid synthase

CTD Direct Evidence: marker/mechanism

PMID:18770866 PMID:20805790 PMID:21213365

NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261

G

FAT atypical cadherin 4

CTD Direct Evidence: marker/mechanism

NCBI chr 2:121,927,266...122,056,700
Ensembl chr 2:121,927,942...122,056,707

G

fibrillin 1

ClinVar Annotator: match by term: Melanoma

PMID:7611299 PMID:8894692 PMID:9401003 PMID:9536098 PMID:10533071 More...

NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889

G

F-box and WD repeat domain containing 7

ClinVar Annotator: match by term: Malignant melanoma, somatic

PMID:25741868 PMID:26619011

NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941

G

FHF complex subunit HOOK interacting protein 2A

CTD Direct Evidence: marker/mechanism

NCBI chr 1:256,417,533...256,444,109
Ensembl chr 1:256,417,788...256,441,617

G

Fms related receptor tyrosine kinase 1

protein:increased expression:serum:
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:19718025 PMID:21730877

NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626

G

FTO, alpha-ketoglutarate dependent dioxygenase

CTD Direct Evidence: marker/mechanism

NCBI chr19:15,284,898...15,692,142
Ensembl chr19:15,349,696...15,692,083

G

GRB2-associated binding protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:151,429,844...151,625,708
Ensembl chr 1:151,429,695...151,625,031

G

growth differentiation factor 15

CTD Direct Evidence: marker/mechanism

NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055

G

gamma-glutamyltransferase 1

disease_progression

RGD

NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442

G

glyoxalase 1

CTD Direct Evidence: marker/mechanism

NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649

G

G protein subunit alpha 11

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Melanoma

PMID:1328859 PMID:2549426 PMID:21083380 PMID:21444680 PMID:22733540 More...

NCBI chr 7:8,163,520...8,177,863
Ensembl chr 7:8,162,750...8,179,812

G

G protein subunit alpha q

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Malignant melanoma, somatic | ClinVar Annotator: match by term: Melanoma

PMID:1328859 PMID:2549426 PMID:18719078 PMID:19078957 PMID:21083380 More...

NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672

G

GNAS complex locus

ClinVar Annotator: match by term: Malignant melanoma, somatic

PMID:1517386 PMID:1594625 PMID:1944469 PMID:2549426 PMID:3720010 More...

NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262

G

golgi associated PDZ and coiled-coil motif containing

CTD Direct Evidence: marker/mechanism

NCBI chr20:31,727,617...31,776,904
Ensembl chr20:31,727,620...31,776,903

G

glycerol-3-phosphate acyltransferase, mitochondrial

CTD Direct Evidence: marker/mechanism

NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639

G

G protein-coupled estrogen receptor 1

severity

protein:increased expression:skin (human)

RGD

NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889

G

glycoprotein hormone subunit alpha 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:203,525,952...203,527,271
Ensembl chr 1:203,526,122...203,527,270

G

glutamate ionotropic receptor NMDA type subunit 2A

CTD Direct Evidence: marker/mechanism

NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637

G

glutamate metabotropic receptor 3

CTD Direct Evidence: marker/mechanism

PMID:21946352 PMID:22842228

NCBI chr 4:24,364,854...24,643,972
Ensembl chr 4:24,365,115...24,609,804

G

glutathione S-transferase pi 1

DNA:polymorphism:cds:p.I50V(human)

RGD

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

histone deacetylase 2

CTD Direct Evidence: marker/mechanism

NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609

G

histone deacetylase 3

associated with Anaphylaxis;

RGD

NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856

G

histone deacetylase 6

CTD Direct Evidence: marker/mechanism

NCBI chr X:14,550,645...14,572,445
Ensembl chr X:14,551,044...14,572,441

G

heat shock protein nuclear import factor hikeshi

CTD Direct Evidence: marker/mechanism

NCBI chr 1:143,825,399...143,849,361
Ensembl chr 1:143,825,923...143,849,363

G

homeobox A9

CTD Direct Evidence: marker/mechanism

NCBI chr 4:81,323,235...81,329,344
Ensembl chr 4:81,323,382...81,326,358

G

homeo box B13

CTD Direct Evidence: marker/mechanism

NCBI chr10:81,160,498...81,162,777
Ensembl chr10:81,160,498...81,162,777

G

homeo box D12

CTD Direct Evidence: marker/mechanism

NCBI chr 3:59,577,677...59,578,798
Ensembl chr 3:59,577,677...59,578,798

G

heparanase

CTD Direct Evidence: marker/mechanism

NCBI chr14:8,896,593...8,937,011
Ensembl chr14:8,896,593...8,937,010

G

HRas proto-oncogene, GTPase

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Malignant melanoma, somatic | ClinVar Annotator: match by term: Melanoma

PMID:1904555 PMID:2999610 PMID:3510078 PMID:3537694 PMID:6092966 More...

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

G

heparan sulfate-glucosamine 3-sulfotransferase 5

CTD Direct Evidence: marker/mechanism

NCBI chr20:40,106,876...40,417,661
Ensembl chr20:40,106,876...40,417,653

G

heat shock protein family A (Hsp70) member 1A

CTD Direct Evidence: marker/mechanism

NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227

G

intercellular adhesion molecule 1

disease_progression

RGD

NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438

G

isocitrate dehydrogenase (NADP(+)) 1

ClinVar Annotator: match by term: Malignant melanoma, somatic

PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20946881 More...

NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708

G

immediate early response 2

disease_progression

mRNA:increased expression:skin (human)

RGD

NCBI chr19:23,494,551...23,496,075
Ensembl chr19:23,494,184...23,499,211

G

interferon, alpha 1

CTD Direct Evidence: therapeutic

PMID:15176220 PMID:15577320 PMID:15577323 PMID:16034308 PMID:16260693 More...

NCBI chr 5:103,097,356...103,097,925
Ensembl chr 5:103,097,356...103,097,925

G

interferon beta 1

CTD Direct Evidence: therapeutic

PMID:16928243 PMID:21846298

NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523

G

interferon gamma

CTD Direct Evidence: therapeutic

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

interleukin 17D

severity

RGD

NCBI chr15:31,671,337...31,688,833

G

interleukin 1 receptor accessory protein-like 1

CTD Direct Evidence: marker/mechanism

NCBI chr X:51,371,969...52,876,726
Ensembl chr X:51,378,215...52,876,772

G

interleukin 1 receptor antagonist

mouse model treated with human protein

RGD

NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445

G

interleukin 2

CTD Direct Evidence: therapeutic

PMID:12374674 PMID:12439608 PMID:15577323 PMID:15917704 PMID:16131448 More...

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

interleukin 21

treatment

RGD

NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996

G

inner centromere protein

CTD Direct Evidence: marker/mechanism

NCBI chr 1:206,520,655...206,550,575
Ensembl chr 1:206,523,380...206,553,265

G

IQ motif containing H

CTD Direct Evidence: marker/mechanism

NCBI chr 8:63,889,816...64,083,248
Ensembl chr 8:63,892,370...64,083,223

G

janus kinase and microtubule interacting protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr18:35,532,552...35,747,938
Ensembl chr18:35,532,552...35,747,775

G

jumonji domain containing 6, arginine demethylase and lysine hydroxylase

CTD Direct Evidence: marker/mechanism

NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182

G

JunB proto-oncogene, AP-1 transcription factor subunit

treatment

human cell line in a mouse model

RGD

NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035

G

lysine demethylase 1A

CTD Direct Evidence: marker/mechanism

NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319

G

lysine demethylase 4A

CTD Direct Evidence: marker/mechanism

NCBI chr 5:131,672,754...131,719,534
Ensembl chr 5:131,672,754...131,719,501

G

lysine demethylase 4B

CTD Direct Evidence: marker/mechanism

NCBI chr 9:1,158,737...1,237,233
Ensembl chr 9:1,158,752...1,236,543

G

lysine demethylase 4C

CTD Direct Evidence: marker/mechanism

NCBI chr 5:88,100,710...88,306,821
Ensembl chr 5:88,100,733...88,306,818

G

lysine demethylase 7A

human gene in a mouse model

RGD

NCBI chr 4:67,899,407...67,974,264
Ensembl chr 4:67,904,307...67,966,998

G

kinase insert domain receptor

disease_progression
treatment

protein:increased expression, altered expression:skin:
protein:increased expression:serum:

RGD

PMID:15714119 PMID:12415261 PMID:21730877

RGD:8551851, RGD:126925192, RGD:8552360

NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018

G

KH RNA binding domain containing, signal transduction associated 2

CTD Direct Evidence: marker/mechanism

NCBI chr 9:34,447,023...34,953,684
Ensembl chr 9:34,447,056...34,915,530

G

kinesin family member 18B

CTD Direct Evidence: marker/mechanism

NCBI chr10:87,870,424...87,889,895
Ensembl chr10:87,870,428...87,889,850

G

KIT proto-oncogene receptor tyrosine kinase

disease_progression

ClinVar Annotator: match by term: MELANOMA, MALIGNANT | ClinVar Annotator: match by term: Malignant melanoma, somatic | ClinVar Annotator: match by term: Melanoma

PMID:7513208 PMID:7530509 PMID:8589724 PMID:9438854 PMID:9657776 More...

NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652

G

killer cell lectin like receptor B1A

CTD Direct Evidence: marker/mechanism

NCBI chr 4:161,890,577...161,904,050
Ensembl chr 4:161,890,577...161,961,675

G

killer cell lectin like receptor K1

CTD Direct Evidence: marker/mechanism

NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459

G

kinetochore-localized astrin/SPAG5 binding protein

ClinVar Annotator: match by term: Malignant melanoma, somatic

NCBI chr 3:105,800,762...105,820,555
Ensembl chr 3:105,800,954...105,820,715

G

KRAS proto-oncogene, GTPase

ClinVar Annotator: match by term: Malignant melanoma, somatic

PMID:2278970 PMID:3122217 PMID:12460918 PMID:15696205 PMID:16361624 More...

NCBI chr 4:178,185,418...178,218,484

G

galectin 3

CTD Direct Evidence: marker/mechanism

NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025

G

interferon alpha-1-like

CTD Direct Evidence: therapeutic

NCBI chr 5:103,227,820...103,230,500

G

LDL receptor related protein 1B

ameliorates

CTD Direct Evidence: marker/mechanism
DNA:mutations:multiple: (human)

CTD
RGD

PMID:22197931 PMID:31164891

NCBI chr 3:24,594,302...26,715,037
Ensembl chr 3:24,594,991...26,715,505

G

leucine rich repeat containing 56

ClinVar Annotator: match by term: MELANOMA, MALIGNANT | ClinVar Annotator: match by term: Malignant melanoma, somatic | ClinVar Annotator: match by term: Melanoma

PMID:1904555 PMID:2999610 PMID:3510078 PMID:3537694 PMID:6092966 More...

NCBI chr 1:196,299,843...196,315,170
Ensembl chr 1:196,299,846...196,315,172

G

lymphotoxin alpha

disease_progression

RGD

NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859

G

latexin

CTD Direct Evidence: marker/mechanism

NCBI chr 2:151,727,556...151,733,426
Ensembl chr 2:151,727,102...151,733,460

G

mitogen activated protein kinase kinase 1

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Malignant melanoma, somatic | ClinVar Annotator: match by term: Melanoma

PMID:7651428 PMID:17366577 PMID:17551924 PMID:17704260 PMID:18060073 More...

NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147

G

mitogen activated protein kinase kinase 2

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Melanoma

PMID:22197931 PMID:24265153 PMID:24265154 PMID:25487361 PMID:28492532

NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243

G

mitogen-activated protein kinase kinase kinase 5

CTD Direct Evidence: marker/mechanism

NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800

G

mitogen-activated protein kinase kinase kinase 9

CTD Direct Evidence: marker/mechanism

NCBI chr 6:101,423,754...101,488,822
Ensembl chr 6:101,430,292...101,488,822

G

mitogen activated protein kinase 1

treatment

RGD

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 14

ameliorates

mouse cell line in a mouse model

RGD

NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589

G

melanocortin 1 receptor

DNA:missense mutations:cds:multiple (human)
ClinVar Annotator: match by term: Malignant Melanoma Susceptibility | ClinVar Annotator: match by term: Melanoma
CTD Direct Evidence: marker/mechanism

ClinVar
CTD
RGD

PMID:7581459 PMID:16809487 PMID:16982779 PMID:17616515 PMID:18366057 More...

RGD:1600619, RGD:6484659

NCBI chr19:51,452,448...51,455,375
Ensembl chr19:51,453,239...51,454,192

G

MDM2 proto-oncogene

CTD Direct Evidence: marker/mechanism

NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915

G

melanotransferrin

CTD Direct Evidence: marker/mechanism

NCBI chr11:68,884,446...68,906,300
Ensembl chr11:68,884,446...68,906,300

G

MET proto-oncogene, receptor tyrosine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876

G

O-6-methylguanine-DNA methyltransferase

protein:increased activity:skin tumor (rat)

RGD

NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756

G

microRNA 340-1

CTD Direct Evidence: marker/mechanism

NCBI chr10:34,393,568...34,393,665
Ensembl chr10:34,393,568...34,393,665

G

melanocyte inducing transcription factor

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Melanoma
mRNA:increased expression:blood

CTD
ClinVar
RGD

PMID:2440678 PMID:22012259 PMID:22080950 PMID:22158021 PMID:23167872 More...

NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145

G

melan-A

CTD Direct Evidence: marker/mechanism

NCBI chr 1:227,469,537...227,483,343
Ensembl chr 1:227,469,537...227,483,343

G

MLLT10, histone lysine methyltransferase DOT1L cofactor

CTD Direct Evidence: marker/mechanism

NCBI chr17:80,821,870...80,949,349
Ensembl chr17:80,822,556...80,949,345

G

matrix metallopeptidase 8

CTD Direct Evidence: therapeutic

NCBI chr 8:4,724,009...4,733,864
Ensembl chr 8:4,724,029...4,733,520

G

mercaptopyruvate sulfurtransferase

CTD Direct Evidence: marker/mechanism

NCBI chr 7:109,955,581...109,963,155
Ensembl chr 7:109,955,675...109,963,141

G

mitochondrial ribosomal protein L49

CTD Direct Evidence: marker/mechanism

NCBI chr 1:203,346,068...203,350,040
Ensembl chr 1:203,332,481...203,350,049

G

methylthioadenosine phosphorylase

CTD Direct Evidence: marker/mechanism

NCBI chr 5:103,874,460...103,920,684
Ensembl chr 5:103,873,020...103,939,406

G

mechanistic target of rapamycin kinase

ClinVar Annotator: match by term: Malignant melanoma, somatic

PMID:20190810 PMID:24631838 PMID:25741868 PMID:26018084 PMID:26619011 More...

NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311

G

mitochondrial poly(A) polymerase

CTD Direct Evidence: marker/mechanism

NCBI chr17:53,320,739...53,341,500
Ensembl chr17:53,320,741...53,341,538

G

MX dynamin like GTPase 2

CTD Direct Evidence: marker/mechanism

NCBI chr11:36,905,698...36,936,308
Ensembl chr11:36,906,111...36,930,342

G

MYD88, innate immune signal transduction adaptor

treatment

mouse cell line in a mouse model

RGD

NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415

G

myosin VIIA

CTD Direct Evidence: marker/mechanism

NCBI chr 1:152,342,611...152,414,171
Ensembl chr 1:152,344,448...152,414,157

G

nuclear assembly factor 1 ribonucleoprotein

DNA:SNP:cds:rs7675988 (human)

RGD

NCBI chr16:22,837,583...22,868,320
Ensembl chr16:22,837,588...22,868,293

G

N-myc downstream regulated 1

CTD Direct Evidence: marker/mechanism

NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880

G

neurofibromin 1

CTD Direct Evidence: marker/mechanism

PMID:25119042 PMID:26214590

NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658

G

nuclear factor kappa B subunit 1

RGD

NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404

G

NFKB inhibitor alpha

RGD

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

NFKB inhibitor epsilon

CTD Direct Evidence: marker/mechanism

NCBI chr 9:15,443,600...15,450,437
Ensembl chr 9:15,436,941...15,450,437

G

nerve growth factor receptor

CTD Direct Evidence: marker/mechanism

NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518

G

natriuretic peptide A

CTD Direct Evidence: therapeutic

NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351

G

NRAS proto-oncogene, GTPase

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Malignant melanoma, somatic | ClinVar Annotator: match by term: Melanoma
associated with Neoplasm Metastasis; DNA:mutation:multiple (human)

CTD
ClinVar
RGD

PMID:1654209 PMID:2278970 PMID:2407301 PMID:2674680 PMID:2989702 More...

NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626

G

5'-nucleotidase domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr20:38,105,677...38,208,613
Ensembl chr20:38,105,678...38,208,591

G

NUF2 component of NDC80 kinetochore complex

disease_progression

RGD

NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766

G

NUS1 dehydrodolichyl diphosphate synthase subunit

CTD Direct Evidence: marker/mechanism

NCBI chr20:31,811,817...31,838,562
Ensembl chr20:31,811,817...31,838,561

G

poly (ADP-ribose) polymerase 1

CTD Direct Evidence: marker/mechanism

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

G

paired box 4

CTD Direct Evidence: marker/mechanism

NCBI chr 4:57,058,453...57,065,995
Ensembl chr 4:57,058,462...57,063,408

G

paired box 6

CTD Direct Evidence: marker/mechanism

NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014

G

programmed cell death 1

treatment

CTD Direct Evidence: therapeutic
associated with influenza

CTD
RGD

PMID:21802280 PMID:27760326

NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937

G

platelet derived growth factor receptor alpha

ClinVar Annotator: match by term: Melanoma

PMID:24132921 PMID:28492532

NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335

G

phosphoglycerate dehydrogenase

CTD Direct Evidence: marker/mechanism

NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

ClinVar Annotator: match by term: Malignant melanoma, somatic | ClinVar Annotator: match by term: Melanoma

PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More...

NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032

G

phosphoinositide-3-kinase regulatory subunit 1

ClinVar Annotator: match by term: Malignant melanoma, somatic

PMID:25157968 PMID:25741868 PMID:26619011

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

G

phosphatidylinositol-5-phosphate 4-kinase type 2 alpha

CTD Direct Evidence: marker/mechanism

NCBI chr17:81,496,669...81,668,180
Ensembl chr17:81,496,670...81,668,029

G

protein kinase, membrane associated tyrosine/threonine 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:12,748,221...12,758,995
Ensembl chr10:12,748,237...12,758,995

G

phospholipase C, beta 4

CTD Direct Evidence: marker/mechanism

NCBI chr 3:122,952,965...123,322,522
Ensembl chr 3:122,953,196...123,322,392

G

premelanosome protein

CTD Direct Evidence: marker/mechanism

NCBI chr 7:1,138,202...1,148,735
Ensembl chr 7:1,138,586...1,148,746

G

proopiomelanocortin

CTD Direct Evidence: therapeutic

NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664

G

protection of telomeres 1

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: MELANOMA, MALIGNANT
ClinVar Annotator: match by term: Malignant melanoma, somatic

PMID:24686846 PMID:24686849 PMID:25741868 PMID:26467025 PMID:28492532 More...

NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042

G

peroxisome proliferator-activated receptor delta

CTD Direct Evidence: therapeutic

NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968

G

peroxisome proliferator-activated receptor gamma

CTD Direct Evidence: marker/mechanism|therapeutic

PMID:14512786 PMID:28962521

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

G

PPARG coactivator 1 alpha

severity

mRNA:increased expression:tumor (human)

RGD

NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656

G

protein phosphatase 1, regulatory (inhibitor) subunit 14B

CTD Direct Evidence: marker/mechanism

NCBI chr 1:204,165,210...204,167,320
Ensembl chr 1:204,163,299...204,167,319
Ensembl chr12:204,163,299...204,167,319

G

protein phosphatase 6, catalytic subunit

CTD Direct Evidence: marker/mechanism

NCBI chr 3:22,929,816...22,962,123
Ensembl chr 3:22,931,577...22,962,113

G

PRAME like, X-linked 1

mRNA:increased expression:skin of body (human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:16179254 PMID:27505074 PMID:9047241

RGD:11535038, RGD:11535062

NCBI chr X:98,567,994...98,574,654
Ensembl chr X:98,569,415...98,572,096

G

peroxiredoxin 2

CTD Direct Evidence: marker/mechanism

NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194

G

serine protease 23

CTD Direct Evidence: marker/mechanism

NCBI chr 1:143,402,725...143,422,182
Ensembl chr 1:143,401,396...143,422,091

G

phosphatase and tensin homolog

ClinVar Annotator: match by term: MELANOMA, MALIGNANT | ClinVar Annotator: match by term: Malignant melanoma, somatic | ClinVar Annotator: match by term: Melanoma
CTD Direct Evidence: marker/mechanism

ClinVar
CTD
RGD

PMID:1097835 PMID:1945792 PMID:9467011 PMID:9915974 PMID:10866302 More...

NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838

G

phosphotriesterase related

CTD Direct Evidence: marker/mechanism

NCBI chr17:76,058,388...76,119,633
Ensembl chr17:76,058,503...76,119,627

G

prostaglandin-endoperoxide synthase 2

CTD Direct Evidence: marker/mechanism

PMID:17145863 PMID:17499752 PMID:18454317

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

protein tyrosine kinase 2 beta

CTD Direct Evidence: marker/mechanism

NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282

G

protein tyrosine phosphatase, receptor type, K

CTD Direct Evidence: marker/mechanism

PMID:22535842 PMID:22842228

NCBI chr 1:16,738,896...17,236,687
Ensembl chr 1:16,850,576...17,103,605

G

protein tyrosine phosphatase, receptor type, O

CTD Direct Evidence: marker/mechanism

NCBI chr 4:170,164,071...170,374,790
Ensembl chr 4:170,164,431...170,374,771

G

glutaminyl-peptide cyclotransferase

CTD Direct Evidence: marker/mechanism

NCBI chr 6:15,964,656...15,996,730
Ensembl chr 6:15,964,657...15,996,711

G

Rac family small GTPase 1

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Malignant melanoma, somatic

PMID:22842228 PMID:25056119 PMID:26619011

NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251

G

Rac family small GTPase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720

G

Raf-1 proto-oncogene, serine/threonine kinase

ClinVar Annotator: match by term: Malignant melanoma, somatic | ClinVar Annotator: match by term: Melanoma

PMID:1760348 PMID:10064593 PMID:12077328 PMID:17603482 PMID:17603483 More...

NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317

G

retinoic acid induced 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:44,913,231...45,008,232
Ensembl chr10:44,947,909...45,008,232

G

Rap1 GTPase-activating protein

protein:decreased expression:epidermal melanocyte (human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:19147557 PMID:22614916 PMID:19147557

NCBI chr 5:149,873,987...149,939,254
Ensembl chr 5:149,892,019...149,939,253

G

RAS p21 protein activator 2

CTD Direct Evidence: marker/mechanism

PMID:26214590 PMID:26502337

NCBI chr 8:97,119,983...97,236,687
Ensembl chr 8:97,118,802...97,236,671

G

retina and anterior neural fold homeobox

CTD Direct Evidence: marker/mechanism

NCBI chr18:59,463,347...59,467,469
Ensembl chr18:59,463,737...59,467,431

G

REC8 meiotic recombination protein

CTD Direct Evidence: marker/mechanism

NCBI chr15:29,109,862...29,117,327
Ensembl chr15:29,109,863...29,117,326

G

regulatory factor X, 6

CTD Direct Evidence: marker/mechanism

NCBI chr20:31,019,784...31,073,266
Ensembl chr20:31,019,829...31,073,147

G

ras homolog family member B

RGD

NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108

G

Ras and Rab interactor 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:202,355,729...202,362,731
Ensembl chr 1:202,355,890...202,362,729

G

ribonuclease T2

human cells in mouse model

RGD

NCBI chr 1:52,576,344...52,603,151
Ensembl chr 1:52,585,929...52,603,147

G

ROS proto-oncogene 1 , receptor tyrosine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr20:31,432,636...31,583,998
Ensembl chr20:31,432,637...31,583,865

G

ribonuclease P/MRP subunit p38

CTD Direct Evidence: marker/mechanism

NCBI chr17:74,914,066...74,917,742
Ensembl chr17:74,908,932...74,927,431

G

ribosomal protein S3

CTD Direct Evidence: marker/mechanism

NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680

G

RT1 class II, locus Ba

susceptibility

DNA:polymorphisms: :

RGD

NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744

G

regulator of telomere elongation helicase 1

DNA:SNP:cds:rs75691080 (human)

RGD

NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348

G

S100 calcium-binding protein A4

CTD Direct Evidence: marker/mechanism

NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254

G

SAC3 domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:203,414,184...203,416,563
Ensembl chr 1:203,414,187...203,416,604

G

succinate dehydrogenase complex subunit D

CTD Direct Evidence: marker/mechanism

NCBI chr 8:50,944,702...50,954,298
Ensembl chr 8:50,944,704...50,954,238

G

SET domain bifurcated histone lysine methyltransferase 1

severity

protein:increased expression:dermis, subcutis, nucleus (human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:21983785 PMID:24673285

NCBI chr 2:182,898,738...182,930,283
Ensembl chr 2:182,898,738...182,930,506

G

splicing factor 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:203,670,016...203,683,432
Ensembl chr 1:203,670,018...203,684,330

G

signal-induced proliferation-associated 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:202,938,532...202,950,672
Ensembl chr 1:202,938,580...202,950,591

G

solute carrier family 15 member 2

CTD Direct Evidence: marker/mechanism

NCBI chr11:64,014,182...64,043,228
Ensembl chr11:64,014,182...64,043,225

G

solute carrier family 17 member 5

CTD Direct Evidence: marker/mechanism

NCBI chr 8:79,394,416...79,429,387

G

solute carrier family 25, member 45

CTD Direct Evidence: marker/mechanism

NCBI chr 1:203,166,362...203,174,473
Ensembl chr 1:203,166,683...203,174,473

G

solute carrier family 35, member G2

CTD Direct Evidence: marker/mechanism

NCBI chr 8:101,085,579...101,113,339
Ensembl chr 8:101,085,545...101,113,349

G

solute carrier family 39 member 12

CTD Direct Evidence: marker/mechanism

NCBI chr17:77,353,761...77,440,384
Ensembl chr17:77,353,805...77,440,353

G

solute carrier family 45, member 2

CTD Direct Evidence: marker/mechanism

PMID:18563784 PMID:21559390

NCBI chr 2:59,963,599...59,996,408
Ensembl chr 2:59,963,706...59,996,317

G

solute carrier family 5 member 5

CTD Direct Evidence: therapeutic

NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697

G

solute carrier family 6 member 11

CTD Direct Evidence: marker/mechanism

NCBI chr 4:147,297,972...147,413,319
Ensembl chr 4:147,297,969...147,413,443

G

small nuclear RNA activating complex, polypeptide 5

ClinVar Annotator: match by term: Melanoma

NCBI chr 8:64,677,204...64,680,769
Ensembl chr 8:64,677,205...64,681,964

G

suppressor of cytokine signaling 1

ameliorates

RGD

NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383

G

superoxide dismutase 2

protein:increased expression:serum:

RGD

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

G

SRY-box transcription factor 2

disease_progression

RGD

NCBI chr 2:117,536,929...117,539,340
Ensembl chr 2:117,536,929...117,539,338

G

secreted phosphoprotein 1

RGD

NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162

G

stress-induced phosphoprotein 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:204,209,433...204,228,452
Ensembl chr 1:204,178,932...204,228,476

G

serine/threonine kinase 11

ClinVar Annotator: match by term: MELANOMA, MALIGNANT | ClinVar Annotator: match by term: Melanoma

PMID:9760200 PMID:10201537 PMID:10208439 PMID:10353780 PMID:15188174 More...

NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315

G

serine/threonine kinase 19

ClinVar Annotator: match by term: Malignant melanoma, somatic

NCBI chr20:3,995,590...4,005,117
Ensembl chr20:3,995,587...4,005,116

G

STN1 subunit of CST complex

DNA:SNP:cds:rs9420907|rs2995264 (human)

RGD

NCBI chr 1:246,391,311...246,429,844
Ensembl chr 1:246,395,613...246,429,531

G

syntaxin 17

CTD Direct Evidence: marker/mechanism

NCBI chr 5:62,446,138...62,506,108
Ensembl chr 5:62,446,187...62,504,451

G

SUZ12 polycomb repressive complex 2 subunit

CTD Direct Evidence: marker/mechanism

NCBI chr10:64,967,035...65,012,916
Ensembl chr10:64,966,967...65,012,738

G

spleen associated tyrosine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410

G

synaptotagmin 4

CTD Direct Evidence: marker/mechanism

NCBI chr18:23,036,973...23,046,380
Ensembl chr18:23,038,378...23,046,332

G

taste receptor, type 2, member 135

CTD Direct Evidence: marker/mechanism

NCBI chr 4:71,292,912...71,293,877
Ensembl chr 4:71,292,912...71,293,877

G

telomerase RNA component

RNA:increased expression:plasma
DNA:SNP:cds:rs10936599|rs12696304 (human)

RGD

PMID:14654933 PMID:25231748

RGD:2291969, RGD:152995261

NCBI chr 2:112,815,654...112,816,041

G

telomerase reverse transcriptase

mRNA:increased expression:plasma
DNA:SNP:cds:rs455433|rs2736100 (human)
CTD Direct Evidence: therapeutic

CTD
RGD

PMID:20856939 PMID:14654933 PMID:25231748

RGD:2291969, RGD:152995261

NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561

G

tissue factor pathway inhibitor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 4:31,981,786...31,986,707
Ensembl chr 4:31,982,178...31,986,600

G

toll-like receptor 4

DNA:polymorphisms:exons:p.D299G (896A>G)(human;)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:22842228 PMID:22552381

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

G

transmembrane protein 132B

CTD Direct Evidence: marker/mechanism

NCBI chr12:30,829,831...31,093,841
Ensembl chr12:30,832,605...31,093,896

G

transmembrane protein 30B

CTD Direct Evidence: marker/mechanism

NCBI chr 6:92,251,626...92,254,702
Ensembl chr 6:92,249,790...92,254,842

G

tenascin C

CTD Direct Evidence: marker/mechanism

NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624

G

tumor necrosis factor

CTD Direct Evidence: therapeutic

PMID:9794839 PMID:9843018 PMID:10379864 PMID:18388930

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

TNF receptor superfamily member 19

CTD Direct Evidence: marker/mechanism

NCBI chr15:35,092,206...35,158,472
Ensembl chr15:35,092,206...35,180,795

G

tumor protein p53

ClinVar Annotator: match by term: Malignant melanoma, somatic | ClinVar Annotator: match by term: Melanoma
ClinVar Annotator: match by term: Malignant Melanoma Susceptibility | ClinVar Annotator: match by term: Malignant melanoma, somatic | ClinVar Annotator: match by term: Melanoma
ClinVar Annotator: match by term: MELANOMA, MALIGNANT | ClinVar Annotator: match by term: Malignant melanoma, somatic
ClinVar Annotator: match by term: Malignant melanoma | ClinVar Annotator: match by term: Malignant melanoma, somatic
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:cds:p.R72P(human)

ClinVar
CTD
RGD

PMID:253702 PMID:1349175 PMID:1359493 PMID:1565143 PMID:1565144 More...

RGD:8547796, RGD:8547833

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

G

transformation/transcription domain-associated protein

CTD Direct Evidence: marker/mechanism

NCBI chr12:9,738,006...9,827,708
Ensembl chr12:9,738,006...9,827,674

G

TSPY-like 4

CTD Direct Evidence: marker/mechanism

NCBI chr20:38,098,756...38,100,752
Ensembl chr20:38,098,677...38,103,053

G

tyrosinase

disease_progression

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:18488027 PMID:19578364 PMID:21559390 PMID:26640592 PMID:8609659 More...

RGD:8694384, RGD:8694387

NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207

G

tyrosinase-related protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:95,280,982...95,299,516
Ensembl chr 5:95,280,982...95,299,516

G

USP6 N-terminal like

CTD Direct Evidence: marker/mechanism

NCBI chr17:71,828,433...71,956,878
Ensembl chr17:71,830,469...71,956,027

G

vitamin D receptor

severity
disease_progression

DNA:SNP:promoter:rs4516035 (human)
DNA:SNPs:exons: (rs731236, rs2228570) (human)

RGD

PMID:19105801 PMID:10690530

RGD:8158067, RGD:8158068

NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677

G

vascular endothelial growth factor A

disease_progression

RGD

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

G

vascular endothelial growth factor C

CTD Direct Evidence: marker/mechanism

NCBI chr16:37,712,251...37,827,845
Ensembl chr16:37,712,262...37,827,848

G

vestigial-like family member 2

CTD Direct Evidence: marker/mechanism

NCBI chr20:31,409,529...31,415,408
Ensembl chr20:31,409,552...31,415,408

G

WD repeat domain 74

CTD Direct Evidence: marker/mechanism

NCBI chr 1:205,631,769...205,636,558
Ensembl chr 1:205,631,824...205,636,563

G

WAP four-disulfide core domain 1

CTD Direct Evidence: marker/mechanism

NCBI chr19:47,720,191...47,739,121
Ensembl chr19:47,720,423...47,739,108

G

X-ray repair cross complementing 3

CTD Direct Evidence: marker/mechanism

PMID:11059748 PMID:15118671

NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444

G

zinc finger protein 438

CTD Direct Evidence: marker/mechanism

NCBI chr17:52,426,221...52,547,472
Ensembl chr17:52,426,221...52,547,472

G

zinc finger protein 831

CTD Direct Evidence: marker/mechanism

NCBI chr 3:163,393,787...163,510,654
Ensembl chr 3:163,438,006...163,509,095

melanoma and neural system tumor syndrome

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cyclin-dependent kinase inhibitor 2A

ClinVar Annotator: match by term: Melanoma and neural system tumor syndrome | ClinVar Annotator: match by term: Melanoma astrocytoma syndrome
CTD Direct Evidence: marker/mechanism

OMIM
ClinVar
CTD

PMID:865368 PMID:2677576 PMID:5001868 PMID:7566978 PMID:7640518 More...

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

Melanoma-Pancreatic Cancer Syndrome

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cyclin-dependent kinase inhibitor 2A

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Melanoma-pancreatic cancer syndrome

OMIM
CTD
ClinVar

PMID:2319082 PMID:2813514 PMID:5001868 PMID:7566978 PMID:7632931 More...

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

Nevus

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

B-Raf proto-oncogene, serine/threonine kinase

no_association

DNA:mutation:cds:p.V600E(human)
DNA:mutation: :T1796A(human)

RGD

PMID:25490715 PMID:14984580

RGD:11567234, RGD:11567261

NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463

G

methylthioadenosine phosphorylase

CTD Direct Evidence: marker/mechanism

NCBI chr 5:103,874,460...103,920,684
Ensembl chr 5:103,873,020...103,939,406

G

phospholipase A2 group VI

CTD Direct Evidence: marker/mechanism

NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114

Nevus Comedonicus

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

NIMA-related kinase 9

ClinVar Annotator: match by term: Nevus comedonicus

NCBI chr 6:104,944,056...104,984,538
Ensembl chr 6:104,944,056...104,984,538

Nevus, Epithelioid and Spindle Cell

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

BRCA1 associated deubiquitinase 1

CTD Direct Evidence: marker/mechanism

NCBI chr16:6,446,709...6,455,535
Ensembl chr16:6,446,709...6,455,535

ocular melanoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

BRCA1 associated deubiquitinase 1

ClinVar Annotator: match by term: Intraocular melanoma

NCBI chr16:6,446,709...6,455,535
Ensembl chr16:6,446,709...6,455,535

G

transmembrane protein 127

ClinVar Annotator: match by term: Intraocular melanoma

PMID:25741868 PMID:28492532

NCBI chr 3:114,466,095...114,478,894
Ensembl chr 3:114,466,171...114,477,519

Pigmented Nevus

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

HRas proto-oncogene, GTPase

ClinVar Annotator: match by term: PIGMENTED MOLES

PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 PMID:16835863 More...

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

G

leucine rich repeat containing 56

ClinVar Annotator: match by term: PIGMENTED MOLES

PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 PMID:16835863 More...

NCBI chr 1:196,299,843...196,315,170
Ensembl chr 1:196,299,846...196,315,172

G

neurofibromin 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658

G

NRAS proto-oncogene, GTPase

ClinVar Annotator: match by term: PIGMENTED MOLES

PMID:1654209 PMID:2278970 PMID:2674680 PMID:3102434 PMID:3122217 More...

NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626

G

SUZ12 polycomb repressive complex 2 subunit

CTD Direct Evidence: marker/mechanism

NCBI chr10:64,967,035...65,012,916
Ensembl chr10:64,966,967...65,012,738

Sebaceous Nevus Syndrome and Hemimegalencephaly

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

HRas proto-oncogene, GTPase

ClinVar Annotator: match by term: Sebaceous nevus syndrome and hemimegalencephaly

PMID:12835555 PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 More...

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

G

KRAS proto-oncogene, GTPase

ClinVar Annotator: match by term: Sebaceous nevus syndrome and hemimegalencephaly

PMID:2278970 PMID:3122217 PMID:7773929 PMID:8439212 PMID:12110640 More...

NCBI chr 4:178,185,418...178,218,484

G

leucine rich repeat containing 56

ClinVar Annotator: match by term: Sebaceous nevus syndrome and hemimegalencephaly

PMID:12835555 PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 More...

NCBI chr 1:196,299,843...196,315,170
Ensembl chr 1:196,299,846...196,315,172

G

NRAS proto-oncogene, GTPase

ClinVar Annotator: match by term: Sebaceous nevus syndrome and hemimegalencephaly

PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More...

NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626

skin melanoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ALF transcription elongation factor 4

disease_progression

RGD

NCBI chr10:37,498,825...37,579,751
Ensembl chr10:37,498,825...37,579,751

G

angiotensinogen

protein:increased expression:serum

RGD

NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977

G

AKT serine/threonine kinase 1

ClinVar Annotator: match by term: Cutaneous melanoma

PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285