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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Infarction
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Accession:DOID:9005600 term browser browse the term
Definition:Formation of an infarct, which is NECROSIS in tissue due to local ISCHEMIA resulting from obstruction of BLOOD CIRCULATION, most commonly by a THROMBUS or EMBOLUS.
Synonyms:exact_synonym: Infarctions
 primary_id: MESH:D007238
 xref: EFO:0009463



show annotations for term's descendants           Sort by:
Infarction term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf3 colony stimulating factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:15135374 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
JBrowse link
G Epas1 endothelial PAS domain protein 1 IEP RGD PMID:12911537 RGD:10395384 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IEP RGD PMID:12911537 RGD:10395384 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Notch3 notch receptor 3 TAS RGD PMID:11925448 RGD:632418 NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025
JBrowse link
G Polr2a RNA polymerase II subunit A IEP RGD PMID:22535878 RGD:9681722 NCBI chr10:54,452,438...54,478,486
Ensembl chr10:54,452,441...54,478,455
JBrowse link
G Prl prolactin ISO CTD Direct Evidence: marker/mechanism CTD PMID:718334 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19141
    Pathological Conditions, Signs and Symptoms 13624
      Pathologic Processes 8326
        ischemia 1502
          Infarction 6
            hepatic infarction 0
Path 2
Term Annotations click to browse term
  disease 19141
    disease of anatomical entity 18453
      cardiovascular system disease 5545
        vascular disease 4027
          ischemia 1502
            Infarction 6
              hepatic infarction 0
paths to the root