Bone Neoplasms - Ontology Report - Rat Genome Database

Submit Data | Help | Video Tutorials | News | Publications | Download | REST API | Citing RGD | Contact

Advanced Search (OLGA)

RGD DISEASE ONTOLOGY - ANNOTATIONS

{{ watchLinkText }}

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:	Bone Neoplasms	go back to main search page
Accession:	DOID:9004389	browse the term
Definition:	Tumors or cancer located in bone tissue or specific BONES.
Synonyms:	exact_synonym:	bone neoplasm; bone tumour; neoplasm of bone; osseous tumor
	primary_id:	MESH:D001859
	alt_id:	RDO:0001001
	xref:	EFO:0003820

show annotations for term's descendants Sort by:
Rat (790) Mouse (839) Human (15250) Chinchilla (657) Bonobo (693) Dog (862) Squirrel (663) Pig (683) Green Monkey (679) Naked Mole-rat (649) All
Genes (709) Strains (4) Cell Lines (77)

Bone Neoplasms

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

BRCA1 associated deubiquitinase 1

CTD Direct Evidence: marker/mechanism

NCBI chr16:6,446,709...6,455,535
Ensembl chr16:6,446,709...6,455,535

G

matrix metallopeptidase 2

CTD Direct Evidence: marker/mechanism

NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870

G

matrix metallopeptidase 9

CTD Direct Evidence: marker/mechanism

NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120

G

nuclear receptor coactivator 3

CTD Direct Evidence: marker/mechanism

NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594

G

plasminogen activator, urokinase

CTD Direct Evidence: marker/mechanism

NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775

G

procollagen lysine, 2-oxoglutarate 5-dioxygenase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255

G

prostaglandin-endoperoxide synthase 2

CTD Direct Evidence: marker/mechanism

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

transforming growth factor, beta receptor 2

CTD Direct Evidence: therapeutic

NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228

Adult Cerebral Astrocytoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

matrix metallopeptidase 1

susceptibility

DNA:insertion:promoter:g.-1607insG (human)

RGD

NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097

anaplastic astrocytoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATRX, chromatin remodeler

ClinVar Annotator: match by term: Astrocytoma, anaplastic

PMID:7697714 PMID:8968741 PMID:18414213 PMID:22995991 PMID:24082139 More...

NCBI chr X:70,850,981...70,997,330
Ensembl chr X:70,850,981...70,997,330

G

KRAS proto-oncogene, GTPase

mRNA:decreased expression:brain

RGD

NCBI chr 4:178,185,418...178,218,484

G

tumor protein p53

ClinVar Annotator: match by term: Astrocytoma, anaplastic

PMID:1349175 PMID:1565143 PMID:1565144 PMID:1591732 PMID:1631137 More...

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

anaplastic ependymoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

partner and localizer of BRCA2

ClinVar Annotator: match by term: Anaplastic ependymoma

PMID:21285249 PMID:25085752 PMID:25741868 PMID:26315354 PMID:26467025 More...

NCBI chr 1:176,665,076...176,689,053
Ensembl chr 1:176,665,076...176,688,990

G

ring finger protein 213

ClinVar Annotator: match by term: Anaplastic ependymoma

NCBI chr10:104,656,329...104,755,669
Ensembl chr10:104,656,883...104,757,918

G

RUNX family transcription factor 1

ClinVar Annotator: match by term: Anaplastic ependymoma

PMID:23753029 PMID:25741868 PMID:26580448 PMID:28492532 PMID:28801348 More...

NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542

astroblastoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

microRNA 542

disease_progression

RGD

NCBI chr X:132,802,623...132,802,701
Ensembl chr X:132,802,623...132,802,701

G

phosphoinositide-3-kinase regulatory subunit 1

severity

RGD

PMID:26956052 PMID:26286747

RGD:11343921, RGD:13782052

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

G

DNA polymerase epsilon, catalytic subunit

ClinVar Annotator: match by term: Neuroepithelial neoplasm

PMID:24033266 PMID:25741868 PMID:26467025 PMID:28492532 PMID:29987844

NCBI chr12:46,345,420...46,393,984
Ensembl chr12:46,345,420...46,393,939

astroblastoma, MN1-altered

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATM serine/threonine kinase

ClinVar Annotator: match by term: Astroblastoma, MN1-altered

PMID:17344846 PMID:20305132 PMID:25741868 PMID:25980754 PMID:26206375 More...

NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437

G

similar to human chromosome 11 open reading frame 65

ClinVar Annotator: match by term: Astroblastoma, MN1-altered

PMID:17344846 PMID:20305132 PMID:25741868 PMID:25980754 PMID:26206375 More...

NCBI chr 8:53,796,033...53,825,277
Ensembl chr 8:53,796,366...53,824,748

G

TSC complex subunit 2

ClinVar Annotator: match by term: Astroblastoma, MN1-altered

PMID:25741868 PMID:28492532

NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951

Bone Metastasis

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

arachidonate 12-lipoxygenase, 12S type

associated with Prostatic Neoplasms;

RGD

NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542

G

BRCA1 interacting DNA helicase 1

associated with Breast Neoplasms; human gene in a mouse model

RGD

NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324

G

C-X-C motif chemokine receptor 4

disease_progression

associated with hepatocellular carcinoma;protein:increased expression:liver (human)

NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883

G

ectonucleotide pyrophosphatase/phosphodiesterase 1

associated with Breast Neoplasms;mRNA:increased expression:bone element (human)

RGD

NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715

G

microRNA 34a

susceptibility

associated with hepatocellular carcinoma;miRNA:decreased expression:serum, bone

RGD

NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103

G

matrix metallopeptidase 13

associated with Carcinoma, Renal Cell; mRNA, protein:increased expression:bone (human)

RGD

NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239

G

platelet derived growth factor D

associated with prostate carcinoma

RGD

NCBI chr 8:3,488,448...3,722,395
Ensembl chr 8:3,488,423...3,722,395

bone osteosarcoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATRX, chromatin remodeler

ClinVar Annotator: match by term: Bone osteosarcoma

PMID:7697714 PMID:23820649 PMID:24690944 PMID:24805811 PMID:25741868 More...

NCBI chr X:70,850,981...70,997,330
Ensembl chr X:70,850,981...70,997,330

G

checkpoint kinase 2

ClinVar Annotator: match by term: Bone osteosarcoma

PMID:3313277 PMID:9536098 PMID:10617473 PMID:11053450 PMID:11298456 More...

NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286

G

EGF containing fibulin extracellular matrix protein 2

exacerbates
disease_progression

mRNA, protein:increased expression:bone tissue (human )
protein:increased expression:bone tissue (human)

RGD

PMID:28339091 PMID:27157136

RGD:42722011, RGD:42722013

NCBI chr 1:202,781,692...202,789,784
Ensembl chr 1:202,781,665...202,789,414

G

RB transcriptional corepressor 1

ClinVar Annotator: match by term: Bone osteosarcoma

PMID:1352883 PMID:2594029 PMID:2601691 PMID:7881418 PMID:8651278 More...

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

G

tumor protein p53

ClinVar Annotator: match by term: Bone osteosarcoma

PMID:1565143 PMID:1565144 PMID:1591732 PMID:1631137 PMID:1683921 More...

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

G

TSC complex subunit 2

ClinVar Annotator: match by term: Bone osteosarcoma

PMID:25741868 PMID:26822237

NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951

brain glioblastoma multiforme

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

eukaryotic translation elongation factor 2

protein:increased expression:brain (human)

RGD

NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183

G

microRNA 139

RNA:decreased expression:brain:

RGD

NCBI chr 1:155,878,828...155,878,895
Ensembl chr 1:155,878,825...155,878,902

G

neural cell adhesion molecule 1

disease_progression

RGD

NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014

G

SUFU negative regulator of hedgehog signaling

human, rat, and/or mouse glioma cells in a mouse model

RGD

NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577

brain glioma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ADAM metallopeptidase domain 3A

DNA:deletion

RGD

NCBI chr16:67,299,949...67,349,970
Ensembl chr16:67,299,949...67,349,968

G

BCL2 associated X, apoptosis regulator

treatment

RGD

PMID:27255231 PMID:29324390

RGD:13792502, RGD:13792598

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

BCL2, apoptosis regulator

treatment

RGD

PMID:27255231 PMID:29324390

RGD:13792502, RGD:13792598

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

baculoviral IAP repeat-containing 3

exacerbates

mRNA:increased expression:brain (human)

NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802

G

baculoviral IAP repeat-containing 5

exacerbates

mRNA:increased expression:brain (human)

NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380

G

bone marrow stromal cell antigen 2

mRNA,protein:increased expression:brain:

RGD

NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979

G

caspase 3

treatment

RGD

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

Fas associated via death domain

treatment

RGD

NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653

G

Fas cell surface death receptor

treatment

RGD

NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591

G

Fas ligand

treatment

RGD

NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215

G

forkhead box A1

disease_progression

RGD

NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188

G

glyceraldehyde-3-phosphate dehydrogenase

RGD

NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235

G

kinase insert domain receptor

protein:increased expression:brain (human)

RGD

NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018

G

microRNA 21

human cells in mouse model; RNA:increased expression:brain (human)

RGD

NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348

G

NLR family, apoptosis inhibitory protein 6

exacerbates

mRNA:increased expression:brain (human)

NCBI chr 2:31,507,423...31,559,098
Ensembl chr 2:31,507,424...31,570,542

G

protein tyrosine phosphatase, receptor type, B

protein:increased expression:brain (human)
human cell in mouse model

RGD

PMID:33900414 PMID:16923162

RGD:151660356, RGD:151660368

NCBI chr 7:51,953,375...52,034,751
Ensembl chr 7:51,930,015...52,034,748

G

vascular endothelial growth factor A

protein:increased expression:brain (human)

RGD

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

G

X-ray repair cross complementing 1

susceptibility

DNA:SNP:exon 10: p.R399Q (human)

RGD

NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701

G

X-ray repair cross complementing 3

susceptibility

DNA:SNP:exon 8: p.T241M (rs861539) (Human)

RGD

NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444

brain stem glioma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

paired box 3

mRNA,protein:increased expression:brain stem:

RGD

NCBI chr 9:79,567,455...79,664,042
Ensembl chr 9:79,568,634...79,664,042

G

platelet derived growth factor receptor alpha

severity

RGD

NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335

cerebellar medulloblastoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

mutS homolog 6

ClinVar Annotator: match by term: Cerebellar medulloblastoma

NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956

childhood astrocytic tumor

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

regulator of telomere elongation helicase 1

ameliorates
susceptibility

DNA:SNP:cds:rs6089953|rs6010620|rs2297440 (human)
DNA:SNP:cds:rs4809324 (human)

RGD

PMID:26014354 PMID:26014354

RGD:152985535, RGD:152985535

NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348

childhood pilocytic astrocytoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

mitogen activated protein kinase 1

protein:increased expression:brain:

RGD

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

chondrosarcoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

chitinase 3 like 1

mRNA:increased expression:tumor (human)

RGD

NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787

G

collagen type II alpha 1 chain

DNA:mutations:multiple (human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:23770606 PMID:23770606

NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546

G

exostosin glycosyltransferase 1

ClinVar Annotator: match by term: Chondrosarcoma | ClinVar Annotator: match by term: Chondrosarcoma, somatic
CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:epiphyseal plate (human)

OMIM
ClinVar
CTD
RGD

PMID:7550340 PMID:8981950 PMID:9521425 PMID:10679937 PMID:10713884 More...

NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357

G

fibroblast growth factor receptor 3

protein:increased expression:growth plate

RGD

NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341

G

mechanistic target of rapamycin kinase

disease_progression

RGD

NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311

G

TATA-box binding protein associated factor 15

extraskeletal myxoid chondrosarcomas (EMC)

RGD

NCBI chr10:68,272,921...68,304,951
Ensembl chr10:68,272,969...68,304,949

chordoid glioma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

protein kinase C, alpha

DNA:mutation:cds:c.1387G>C,p.D463H(human)

RGD

NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012

chordoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

BRCA2, DNA repair associated

ClinVar Annotator: match by term: Chordoma

PMID:186727 PMID:10923033 PMID:11304778 PMID:11873550 PMID:11920621 More...

NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567

G

partner and localizer of BRCA2

ClinVar Annotator: match by term: Chordoma

PMID:25085752 PMID:25741868 PMID:26283626 PMID:26315354 PMID:27106063 More...

NCBI chr 1:176,665,076...176,689,053
Ensembl chr 1:176,665,076...176,688,990

G

T-box transcription factor T

CTD Direct Evidence: marker/mechanism

PMID:19801981 PMID:23064415

NCBI chr 1:52,298,104...52,309,813
Ensembl chr 1:52,298,099...52,305,864

chromosome 13q14 deletion syndrome

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aconitate decarboxylase 1

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529

G

ALG11, alpha-1,2-mannosyltransferase

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr16:69,940,540...69,951,617
Ensembl chr16:69,944,349...69,951,601

G

ARF like GTPase 11

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:35,483,330...35,485,579
Ensembl chr15:35,480,018...35,496,596

G

ATPase copper transporting beta

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636

G

bora, aurora kinase A activator

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:75,797,624...75,835,599
Ensembl chr15:75,797,891...75,821,322

G

similar to human chromosome 13 open reading frame 42

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:36,674,840...36,701,304
Ensembl chr15:36,677,527...36,701,211

G

calcium binding protein 39-like

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:33,606,588...33,710,518
Ensembl chr15:33,606,694...33,743,545

G

coiled-coil domain containing 70

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr16:70,037,309...70,042,401
Ensembl chr16:70,037,309...70,042,339

G

cytidine and dCMP deaminase domain containing 1

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:33,726,590...33,755,611
Ensembl chr15:33,723,435...33,755,576

G

cytoskeleton associated protein 2

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913

G

CLN5, intracellular trafficking protein

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:79,893,573...79,903,438
Ensembl chr15:79,893,548...79,903,438
Ensembl chr 2:79,893,548...79,903,438

G

chondromodulin

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:55,041,548...55,066,297
Ensembl chr15:55,041,561...55,066,297

G

COMM domain containing 6

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:78,467,333...78,474,382
Ensembl chr15:78,467,804...78,474,382

G

cysteinyl leukotriene receptor 2

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:48,189,476...48,228,750
Ensembl chr15:48,189,073...48,304,136

G

dachshund family transcription factor 1

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:74,528,122...74,909,811
Ensembl chr15:74,529,208...74,909,922

G

diaphanous-related formin 3

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:62,543,375...63,013,060
Ensembl chr15:62,543,375...63,012,975

G

DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:75,820,040...75,850,450
Ensembl chr15:75,823,436...75,850,642

G

deleted in lymphocytic leukemia, 7

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:36,479,533...36,495,730
Ensembl chr15:36,479,534...36,495,697

G

EBP like

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:35,508,074...35,531,472
Ensembl chr15:35,508,074...35,531,472

G

endothelin receptor type B

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115

G

family with sequence similarity 124 member A

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:36,799,836...36,855,062
Ensembl chr15:36,799,877...36,853,683

G

F-box and leucine-rich repeat protein 3

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:79,906,795...79,926,678
Ensembl chr15:79,906,795...79,927,867

G

fibronectin type III domain containing 3a

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:47,689,909...47,867,354
Ensembl chr15:47,689,919...47,866,784

G

integrator complex subunit 6

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:36,908,966...37,048,043
Ensembl chr15:36,933,724...37,021,527

G

integral membrane protein 2B

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:48,545,998...48,568,904
Ensembl chr15:48,546,001...48,568,917

G

potassium channel regulator

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:35,774,456...35,779,409
Ensembl chr15:35,774,326...35,779,415

G

potassium channel tetramerization domain containing 12

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:79,800,078...79,806,017
Ensembl chr15:79,801,191...79,806,282

G

KLF transcription factor 12

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:76,628,778...77,062,000
Ensembl chr15:76,637,654...77,062,056

G

KLF transcription factor 5

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445

G

kelch-like family member 1

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:72,698,191...73,142,726
Ensembl chr15:72,699,094...73,142,594

G

karyopherin subunit alpha 3

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:35,536,310...35,610,066
Ensembl chr15:35,536,316...35,610,419

G

LIM domain 7

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:78,566,999...78,769,833
Ensembl chr15:78,567,023...78,769,783

G

lysophosphatidic acid receptor 6

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:48,416,548...48,418,357
Ensembl chr15:48,416,544...48,422,331

G

mediator complex subunit 4

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:48,696,542...48,706,818
Ensembl chr15:48,696,511...48,706,820

G

MYC binding protein 2

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:79,937,354...80,175,432
Ensembl chr15:79,937,354...80,175,498

G

mitotic spindle organizing protein 1

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:75,787,281...75,797,589
Ensembl chr15:75,786,994...75,797,589

G

Nedd4 family interacting protein 2

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:82,032,366...82,087,043
Ensembl chr15:82,032,366...82,086,317

G

NIMA-related kinase 3

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr16:69,867,020...69,892,477
Ensembl chr16:69,867,047...69,892,508

G

NIMA-related kinase 5

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr16:69,895,414...69,938,668
Ensembl chr16:69,895,422...69,939,429

G

nudix hydrolase 15

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:48,707,776...48,713,847
Ensembl chr15:48,709,700...48,747,363

G

ORC ubiquitin ligase 1

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:81,269,413...81,308,734
Ensembl chr15:81,269,416...81,308,734

G

olfactomedin 4

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:55,385,100...55,429,687
Ensembl chr15:55,407,148...55,429,681

G

protocadherin 17

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:60,222,088...60,316,172
Ensembl chr15:60,222,004...60,313,999

G

protocadherin 20

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:64,425,534...64,431,790
Ensembl chr15:64,425,534...64,431,790

G

protocadherin 8

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:55,198,470...55,203,039
Ensembl chr15:55,198,459...55,205,872

G

protocadherin 9

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:69,340,108...70,237,531
Ensembl chr15:69,340,645...70,237,538

G

PHD finger protein 11

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:33,390,290...33,414,647
Ensembl chr15:33,390,292...33,413,009

G

progesterone immunomodulatory binding factor 1

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:75,850,389...76,019,711
Ensembl chr15:75,850,624...76,019,712

G

POU class 4 homeobox 1

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:81,253,714...81,260,057
Ensembl chr15:81,257,781...81,259,728

G

proline rich 20E

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr 4:121,566,632...121,574,734
Ensembl chr 4:121,571,797...121,573,140

G

RB transcriptional corepressor 1

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

G

RNA binding motif protein 26

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:81,884,783...81,964,245
Ensembl chr15:81,887,219...81,964,118

G

RCC1 and BTB domain containing protein 1

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:33,319,586...33,362,421
Ensembl chr15:33,319,586...33,365,302

G

RCC1 and BTB domain containing protein 2

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:48,319,809...48,364,441
Ensembl chr15:48,323,866...48,383,750

G

ribonuclease H2, subunit B

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:36,541,200...36,592,016
Ensembl chr15:36,541,218...36,584,118

G

sciellin

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:80,339,661...80,456,546
Ensembl chr15:80,339,951...80,456,372

G

serpin family E member 3

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:36,908,816...36,931,825
Ensembl chr15:36,907,131...36,933,150

G

SET domain bifurcated histone lysine methyltransferase 2

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:33,553,657...33,606,586
Ensembl chr15:33,453,952...33,606,470

G

SLAIN motif family, member 1

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:80,482,818...80,542,461
Ensembl chr15:80,482,367...80,542,350

G

SLIT and NTRK-like family, member 1

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:85,723,252...85,727,290
Ensembl chr15:85,724,475...85,727,509

G

SLIT and NTRK-like family, member 6

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:87,563,506...87,570,125
Ensembl chr15:87,563,322...87,570,393

G

sprouty RTK signaling antagonist 2

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:82,692,291...82,697,408
Ensembl chr15:82,692,143...82,698,009

G

SPRY domain containing 7

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:35,707,185...35,727,704
Ensembl chr15:35,707,060...35,727,509

G

succinate-CoA ligase ADP-forming subunit beta

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:48,752,356...48,805,495
Ensembl chr15:48,752,312...48,805,138

G

SGT1 homolog, MIS12 kinetochore complex assembly cochaperone

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:54,991,419...55,032,244
Ensembl chr15:54,990,672...55,069,150

G

TBC1 domain family, member 4

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265

G

tudor domain containing 3

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:63,340,531...63,497,208
Ensembl chr15:63,341,235...63,476,110

G

thrombospondin type 1 domain containing 1

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr16:69,771,408...69,804,844
Ensembl chr16:69,771,408...69,801,504

G

tripartite motif-containing 13

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:35,733,548...35,772,676
Ensembl chr15:35,734,107...35,772,677

G

ubiquitin C-terminal hydrolase L3

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:78,485,304...78,527,355
Ensembl chr15:78,485,315...78,527,355
Ensembl chr 3:78,485,315...78,527,355

G

vacuolar protein sorting 36 homolog

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr16:69,810,404...69,834,789
Ensembl chr16:69,808,193...69,834,810

G

WD repeat and FYVE domain containing 2

ClinVar Annotator: match by term: Chromosome 13q14 deletion syndrome

NCBI chr15:37,083,842...37,209,559
Ensembl chr15:37,042,987...37,209,304

desmoplastic/nodular medulloblastoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

actin related protein 1A

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:245,237,821...245,256,618
Ensembl chr 1:245,237,826...245,256,495

G

AT-rich interaction domain 2

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 7:127,447,192...127,565,987
Ensembl chr 7:127,447,278...127,563,512

G

ARF like GTPase 3

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:245,400,659...245,446,673
Ensembl chr 1:245,400,550...245,446,820

G

arsenite methyltransferase

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:245,595,939...245,628,921
Ensembl chr 1:245,596,108...245,627,872

G

ATP synthase membrane subunit K

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:245,973,910...245,980,702
Ensembl chr 1:245,973,914...245,980,761
Ensembl chr10:245,973,914...245,980,761

G

BLOC-1 related complex subunit 7

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:245,564,347...245,578,182
Ensembl chr 1:245,564,369...245,579,343

G

similar to human chromosome 10 open reading frame 95

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:245,210,228...245,212,080
Ensembl chr 1:245,210,973...245,211,602

G

calcium homeostasis modulator 1

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:246,030,269...246,032,988
Ensembl chr 1:246,030,269...246,032,988

G

calcium homeostasis modulator family member 2

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:246,022,324...246,028,050
Ensembl chr 1:246,022,324...246,028,218

G

calcium homeostasis modulator 3

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:246,043,258...246,048,259
Ensembl chr 1:246,043,258...246,048,259

G

cilia and flagella associated protein 43

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:246,625,259...246,712,438
Ensembl chr 1:246,625,262...246,712,443

G

cilia and flagella associated protein 58

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:246,802,691...246,911,363
Ensembl chr 1:246,802,665...246,911,374

G

cyclin and CBS domain divalent metal cation transport mediator 2

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:245,643,682...245,769,542
Ensembl chr 1:245,643,768...245,763,286

G

collagen type XVII alpha 1 chain

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:246,530,589...246,577,559
Ensembl chr 1:246,531,367...246,577,632

G

CCCTC-binding factor

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr19:33,521,726...33,571,124
Ensembl chr19:33,529,319...33,571,123

G

cytochrome P450, family 17, subfamily a, polypeptide 1

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573

G

glutathione S-transferase omega 1

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468

G

glutathione S-transferase omega 2

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:246,731,314...246,757,592
Ensembl chr 1:246,732,089...246,753,866

G

internexin neuronal intermediate filament protein, alpha

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:245,896,775...245,908,330
Ensembl chr 1:245,896,775...245,908,330

G

inositol 1,4,5-trisphosphate receptor interacting protein

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:246,762,804...246,786,379
Ensembl chr 1:246,762,472...246,786,408

G

major facilitator superfamily domain containing 13A

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:245,216,610...245,236,314
Ensembl chr 1:245,217,067...245,236,767

G

neuralized E3 ubiquitin protein ligase 1

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:246,066,830...246,152,890
Ensembl chr 1:246,067,100...246,152,903

G

5'-nucleotidase, cytosolic II

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:245,770,993...245,896,925
Ensembl chr 1:245,772,277...245,897,913

G

polycomb group ring finger 6

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:245,925,354...245,944,964
Ensembl chr 1:245,925,360...245,944,914

G

programmed cell death 11

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:245,980,840...246,021,999
Ensembl chr 1:245,980,880...246,021,999

G

SWI5-dependent homologous recombination repair protein 1

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:246,619,235...246,623,250
Ensembl chr 1:246,597,044...246,623,250

G

sideroflexin 2

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:245,447,014...245,459,312
Ensembl chr 1:245,447,015...245,468,411
Ensembl chr 1:245,447,015...245,468,411

G

SH3 and PX domains 2A

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:246,153,660...246,359,806
Ensembl chr 1:246,160,502...246,360,166

G

STE20-like kinase

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:246,473,712...246,529,643
Ensembl chr 1:246,473,712...246,526,530

G

sortilin-related VPS10 domain containing receptor 3

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:247,099,178...247,734,027
Ensembl chr 1:247,099,408...247,734,027

G

STN1 subunit of CST complex

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:246,391,311...246,429,844
Ensembl chr 1:246,395,613...246,429,531

G

SUFU negative regulator of hedgehog signaling

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577

G

TATA-box binding protein associated factor 5

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:245,958,428...245,973,914
Ensembl chr 1:245,958,428...245,973,914

G

tripartite motif-containing 8

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:245,369,632...245,384,513
Ensembl chr 1:245,369,632...245,384,513

G

WW domain binding protein 1-like

ClinVar Annotator: match by term: Desmoplastic/nodular medulloblastoma

NCBI chr 1:245,472,292...245,528,627
Ensembl chr 1:245,472,296...245,528,627

diffuse intrinsic pontine glioma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

BRCA1 interacting DNA helicase 1

ClinVar Annotator: match by term: Diffuse intrinsic pontine glioma

PMID:16116424 PMID:16116426 PMID:16973432 PMID:18510924 PMID:19099189 More...

NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324

G

neurofibromin 1

ClinVar Annotator: match by term: Diffuse intrinsic pontine glioma

PMID:25741868 PMID:28492532

NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658

diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ALK receptor tyrosine kinase

ClinVar Annotator: match by term: Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype

PMID:25741868 PMID:28492532

NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034

G

BRCA2, DNA repair associated

ClinVar Annotator: match by term: Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype

PMID:25741868 PMID:26467025 PMID:28492532

NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567

G

cyclin-dependent kinase 4

ClinVar Annotator: match by term: Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype

PMID:25741868 PMID:28492532

NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403

G

FA complementation group A

ClinVar Annotator: match by term: Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype

NCBI chr19:51,304,126...51,362,586
Ensembl chr19:51,304,021...51,362,527

G

fibroblast growth factor receptor 3

ClinVar Annotator: match by term: Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype

PMID:25741868 PMID:28492532

NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341

G

isocitrate dehydrogenase (NADP(+)) 1

ClinVar Annotator: match by term: Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype

NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708

G

lysine demethylase 5B

ClinVar Annotator: match by term: Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype

NCBI chr13:46,001,589...46,073,868
Ensembl chr13:46,002,542...46,073,872

G

neurofibromin 1

ClinVar Annotator: match by term: Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype

PMID:25741868 PMID:26740943 PMID:28492532 PMID:31882575

NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658

G

partner and localizer of BRCA2

ClinVar Annotator: match by term: Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype

NCBI chr 1:176,665,076...176,689,053
Ensembl chr 1:176,665,076...176,688,990

G

PMS1 homolog 2, mismatch repair system component

ClinVar Annotator: match by term: Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype

PMID:23435383 PMID:25741868 PMID:28492532 PMID:35451539

NCBI chr12:10,676,818...10,701,161
Ensembl chr12:10,676,764...10,701,066

G

ret proto-oncogene

ClinVar Annotator: match by term: Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype

PMID:22648184 PMID:25741868 PMID:28492532 PMID:28946813 PMID:31159747 More...

NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176

G

succinate dehydrogenase complex flavoprotein subunit A

ClinVar Annotator: match by term: Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype

PMID:25741868 PMID:28492532

NCBI chr 1:28,935,965...28,960,936
Ensembl chr 1:28,940,164...28,961,535

G

tumor protein p53

ClinVar Annotator: match by term: Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype

PMID:1349175 PMID:1565143 PMID:1565144 PMID:1631137 PMID:8401536 More...

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

G

tetraspanin 31

ClinVar Annotator: match by term: Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype

PMID:25741868 PMID:28492532

NCBI chr 7:62,889,552...62,892,428
Ensembl chr 7:62,889,552...62,898,388

dysembryoplastic neuroepithelial tumor

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

B-Raf proto-oncogene, serine/threonine kinase

DNA:mutation:cds:p.V600E(human)

RGD

NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463

Ependymomas

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

BAF chromatin remodeling complex subunit BCL7C

CTD Direct Evidence: marker/mechanism

NCBI chr 1:182,277,163...182,324,274
Ensembl chr 1:182,260,164...182,324,163

G

Eph receptor B2

CTD Direct Evidence: marker/mechanism

NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059

G

glial cell derived neurotrophic factor

CTD Direct Evidence: marker/mechanism

NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209

G

insulin-like growth factor 2

mRNA:increased expression:cerebellum

RGD

NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018

G

RAB3A, member RAS oncogene family

CTD Direct Evidence: marker/mechanism

NCBI chr16:18,684,185...18,688,297
Ensembl chr16:18,684,188...18,688,336

G

retbindin

CTD Direct Evidence: marker/mechanism

NCBI chr19:23,197,506...23,205,544
Ensembl chr19:23,197,506...23,204,438

G

SHC adaptor protein 3

DNA:amplification:brain:

RGD

NCBI chr17:13,652,247...13,772,710
Ensembl chr17:13,651,202...13,772,710

G

zinc finger protein 668

CTD Direct Evidence: marker/mechanism

NCBI chr 1:182,474,633...182,484,957
Ensembl chr 1:182,474,633...182,492,878

extraskeletal myxoid chondrosarcoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

nuclear receptor subfamily 4, group A, member 3

CTD Direct Evidence: marker/mechanism

NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733

G

TATA-box binding protein associated factor 15

ClinVar Annotator: match by term: TAF15-related condition
CTD Direct Evidence: marker/mechanism

OMIM
ClinVar
CTD

PMID:25741868 PMID:28492532

NCBI chr10:68,272,921...68,304,951
Ensembl chr10:68,272,969...68,304,949

Familial Cystic Parathyroid Adenomatosis

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cell division cycle 73

ClinVar Annotator: match by term: Cystic parathyroid adenoma

NCBI chr13:55,357,226...55,449,690
Ensembl chr13:55,357,226...55,449,656

familial retinoblastoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

RB transcriptional corepressor 1

DNA:mutations:promoter, intron, exon:multiple
ClinVar Annotator: match by term: Hereditary retinoblastoma

PMID:7881418 PMID:8346255 PMID:8605116 PMID:8651278 PMID:9536098 More...

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

fibrillary astrocytoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

KRAS proto-oncogene, GTPase

mRNA:decreased expression:brain

RGD

NCBI chr 4:178,185,418...178,218,484

glioblastoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

actin related protein 3

mRNA:increased expression:brain (human)

RGD

NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124

G

adhesion G protein-coupled receptor B1

treatment

mRNA:decreased expression:brain:

RGD

PMID:16244591 PMID:12507886

RGD:13831352, RGD:13831355

NCBI chr 7:106,404,827...106,476,902
Ensembl chr 7:106,404,958...106,476,902

G

adhesion G protein-coupled receptor L4

treatment
severity

RGD

PMID:27416955 PMID:23096411 PMID:23096411

RGD:13838664, RGD:13838665, RGD:13838665

NCBI chr 2:240,354,909...240,457,231
Ensembl chr 2:240,354,941...240,457,225

G

AKT serine/threonine kinase 1

RGD

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

AKT serine/threonine kinase 3

disease_progression

RGD

NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708

G

APC regulator of WNT signaling pathway

CTD Direct Evidence: marker/mechanism

NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696

G

arrestin, beta 2

ameliorates

RGD

NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850

G

assembly factor for spindle microtubules

mRNA:increased expression:brain:

RGD

NCBI chr13:51,074,849...51,123,755
Ensembl chr13:51,074,849...51,123,755

G

ATM serine/threonine kinase

ClinVar Annotator: match by term: Glioblastoma

PMID:9054948 PMID:19781682 PMID:23322442 PMID:23807571 PMID:25525159 More...

NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437

G

ATRX, chromatin remodeler

disease_progression

RGD

NCBI chr X:70,850,981...70,997,330
Ensembl chr X:70,850,981...70,997,330

G

BAG cochaperone 3

treatment

RGD

NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858

G

butyrylcholinesterase

CTD Direct Evidence: marker/mechanism

NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148

G

beclin 1

disease_progression

RGD

NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742

G

basic helix-loop-helix family, member e40

CTD Direct Evidence: marker/mechanism

NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774

G

baculoviral IAP repeat-containing 3

exacerbates

mRNA:increased expression:brain (human)

NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802

G

BMI1 proto-oncogene, polycomb ring finger

CTD Direct Evidence: marker/mechanism

NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690

G

bromodomain containing 2

CTD Direct Evidence: marker/mechanism

NCBI chr20:4,727,078...4,735,389
Ensembl chr20:4,728,151...4,735,388

G

bromodomain containing 4

CTD Direct Evidence: marker/mechanism

PMID:26455392 PMID:27388964

NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539

G

bromodomain containing 7

protein:increased expression:brain:

RGD

NCBI chr19:18,708,792...18,737,497
Ensembl chr19:18,709,022...18,737,494

G

similar to human chromosome 11 open reading frame 65

ClinVar Annotator: match by term: Glioblastoma

PMID:9054948 PMID:19781682 PMID:23322442 PMID:23807571 PMID:25525159 More...

NCBI chr 8:53,796,033...53,825,277
Ensembl chr 8:53,796,366...53,824,748

G

chromobox 6

disease_progression

mRNA,protein:decreased expression:astrocyte:

RGD

NCBI chr 7:111,372,979...111,383,026
Ensembl chr 7:111,372,980...111,383,091

G

chromobox 7

disease_progression

mRNA,protein:decreased expression:astrocyte:

RGD

NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973

G

chromobox 8

mRNA:increased expression:astrocyte:

RGD

NCBI chr10:104,294,518...104,296,956
Ensembl chr10:104,294,518...104,297,024

G

cyclin H

CTD Direct Evidence: marker/mechanism

NCBI chr 2:15,835,064...15,855,648
Ensembl chr 2:15,834,833...15,855,819

G

CD9 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222

G

cyclin-dependent kinase 4

DNA:amplication

RGD

NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403

G

cyclin-dependent kinase 6

severity

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:20534551 PMID:10884881

NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634

G

cyclin-dependent kinase inhibitor 2A

treatment

RGD

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

G

cyclin-dependent kinase inhibitor 2A, variant 1

treatment

RGD

G

chromatin assembly factor 1 subunit B

protein:increased expression:brain:

RGD

NCBI chr11:33,200,894...33,221,076
Ensembl chr11:33,200,981...33,221,070

G

chitinase 3 like 1

mRNA:increased expression:brain, tumor (human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:21029458 PMID:11161003

NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787

G

carboxypeptidase E

disease_progression

mRNA, protein:decreased expression:brain tumor (human)

RGD

NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233

G

cytoplasmic polyadenylation element binding protein 1

disease_progression

RGD

NCBI chr 1:135,300,048...135,407,688
Ensembl chr 1:135,300,461...135,409,760

G

cystatin A

CTD Direct Evidence: marker/mechanism

NCBI chr11:64,620,483...64,631,488
Ensembl chr11:64,620,483...64,631,488

G

cystatin B

CTD Direct Evidence: marker/mechanism

NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526

G

catenin delta 2

CTD Direct Evidence: marker/mechanism

NCBI chr 2:81,168,525...82,016,495
Ensembl chr 2:81,167,117...82,015,764

G

cathepsin B

protein:increased expression:glioma cell (human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:22287159 PMID:17898873

NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500

G

cathepsin H

protein:increased expression:brain

RGD

NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824

G

cathepsin K

CTD Direct Evidence: marker/mechanism

NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550

G

deuterosome assembly protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:12,380,300...12,442,649
Ensembl chr 8:12,380,302...12,442,199

G

deleted in malignant brain tumors 1

DNA:deletion

RGD

NCBI chr 1:185,617,469...185,696,476
Ensembl chr 1:185,617,294...185,696,478

G

DNA methyltransferase 3 alpha

ClinVar Annotator: match by term: Glioblastoma

NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687

G

dual specificity phosphatase 6

CTD Direct Evidence: marker/mechanism

NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185

G

E2F transcription factor 1

disease_progression

RGD

NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361

G

epidermal growth factor

susceptibility

CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter:+61A>G(human)

CTD
RGD

PMID:16598420 PMID:22481252

NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064

G

epidermal growth factor receptor

CTD Direct Evidence: marker/mechanism

PMID:19204207 PMID:23917401 PMID:26455392

NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382

G

ectonucleotide pyrophosphatase/phosphodiesterase 1

severity

protein:increased expression:brain (human)

RGD

NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715

G

enhancer of zeste 2 polycomb repressive complex 2 subunit

treatment

RGD

NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362

G

fatty acid binding protein 7

severity

mRNA, protein:increased expression:brain (human)

RGD

NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880

G

family with sequence similarity 83, member D

CTD Direct Evidence: marker/mechanism

NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192

G

FAT atypical cadherin 1

CTD Direct Evidence: marker/mechanism

NCBI chr16:47,177,253...47,296,261
Ensembl chr16:47,177,248...47,296,107

G

Fms related receptor tyrosine kinase 3 ligand

treatment

RGD

NCBI chr 1:95,615,056...95,620,463
Ensembl chr 1:95,609,370...95,620,463

G

fibronectin 1

CTD Direct Evidence: marker/mechanism

NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678

G

FOS like 2, AP-1 transcription factor subunit

CTD Direct Evidence: marker/mechanism

NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034

G

frataxin

RGD

NCBI chr 1:221,874,007...221,897,543
Ensembl chr 1:221,872,420...221,897,540

G

glial cell derived neurotrophic factor

CTD Direct Evidence: marker/mechanism

NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209

G

glutamate ionotropic receptor kainate type subunit 2

CTD Direct Evidence: marker/mechanism

NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375

G

glutathione S-transferase theta 1

CTD Direct Evidence: marker/mechanism

NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585

G

H2A.X variant histone

CTD Direct Evidence: marker/mechanism

NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239

G

H3.3 histone A

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Glioblastoma

PMID:22286216 PMID:23817572 PMID:26822237

NCBI chr13:92,533,289...92,544,902
Ensembl chr13:92,533,298...92,544,908

G

HEAT repeat containing 1

mRNA, protein:increased expression:brain

RGD

NCBI chr17:58,053,288...58,093,895
Ensembl chr17:58,051,700...58,093,948

G

hes family bHLH transcription factor 1

CTD Direct Evidence: marker/mechanism

NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192

G

hes-related family bHLH transcription factor with YRPW motif 1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312

G

hypoxia inducible factor 1 subunit alpha

CTD Direct Evidence: marker/mechanism

NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261

G

homeo box D10

CTD Direct Evidence: marker/mechanism

NCBI chr 3:59,594,516...59,597,725
Ensembl chr 3:59,594,516...59,597,725

G

HRas proto-oncogene, GTPase

severity

DNA:missense mutation:cds:p.G61L(human)
ClinVar Annotator: match by term: Glioblastoma | ClinVar Annotator: match by term: Glioblastoma, somatic

PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More...

RGD:13702475, RGD:13702872

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

G

isocitrate dehydrogenase (NADP(+)) 1

disease_progression
onset

DNA:mutation:cds:p.R132(human)
ClinVar Annotator: match by term: Glioblastoma, somatic
DNA:mutation:cds:p.R132H(human)

PMID:18772396 PMID:21446021 PMID:25043048 PMID:25741868 PMID:36201590 More...

RGD:11074562, RGD:11522732

NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708

G

interleukin 16

protein:increased expression:brain

RGD

NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130

G

interleukin 1 beta

CTD Direct Evidence: marker/mechanism

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 2

CTD Direct Evidence: therapeutic

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

jagged canonical Notch ligand 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209

G

jagged canonical Notch ligand 2

CTD Direct Evidence: marker/mechanism

NCBI chr 6:131,983,059...132,005,665
Ensembl chr 6:131,983,056...132,005,818

G

potassium voltage-gated channel subfamily C member 2

mRNA:splice variant (human)

RGD

NCBI chr 7:47,700,035...47,883,979
Ensembl chr 7:47,700,288...47,883,968

G

kinase insert domain receptor

treatment

RGD

NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018

G

KRAS proto-oncogene, GTPase

treatment

mRNA:decreased expression:brain

RGD

PMID:16166301 PMID:19179066

RGD:13702861, RGD:13702872

NCBI chr 4:178,185,418...178,218,484

G

L1 cell adhesion molecule

mRNA:decreased expression:brain, temporal lobe (human)

RGD

NCBI chr X:151,597,270...151,623,776
Ensembl chr X:151,597,277...151,623,857

G

leucine rich repeat containing 59

CTD Direct Evidence: marker/mechanism

NCBI chr10:79,572,295...79,586,953
Ensembl chr10:79,572,317...79,602,533

G

latent transforming growth factor beta binding protein 4

CTD Direct Evidence: marker/mechanism

NCBI chr 1:82,600,136...82,634,346
Ensembl chr 1:82,600,136...82,632,178

G

leucine zipper like post translational regulator 1

CTD Direct Evidence: marker/mechanism
DNA:mutations:multiple (human)

CTD
RGD

PMID:23917401 PMID:23917401

NCBI chr11:83,487,717...83,503,896
Ensembl chr11:83,487,717...83,503,633

G

macrophage immunometabolism regulator

CTD Direct Evidence: marker/mechanism

NCBI chr 9:98,420,760...98,440,818
Ensembl chr 9:98,420,376...98,441,733

G

microtubule-associated protein 1 light chain 3 alpha

treatment

RGD

NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670

G

mitogen activated protein kinase kinase 2

treatment

RGD

NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243

G

mitogen activated protein kinase kinase 3

disease_progression

protein:increased expression, increased phosphorylation:brain

RGD

NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492

G

MDM2 proto-oncogene

DNA:amplication

RGD

NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915

G

MDM4 regulator of p53

CTD Direct Evidence: marker/mechanism

NCBI chr13:44,432,596...44,516,165
Ensembl chr13:44,406,213...44,474,226

G

mediator complex subunit 12

ClinVar Annotator: match by term: Glioblastoma

NCBI chr X:66,404,807...66,427,775
Ensembl chr X:66,404,760...66,428,387

G

MET proto-oncogene, receptor tyrosine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876

G

O-6-methylguanine-DNA methyltransferase

DNA:transition:cds:p.L84F (human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:20131314 PMID:22162573 PMID:14669534

NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756

G

microRNA 21

ameliorates

RGD

NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348

G

microRNA 31

RNA:decreased expression:brain (human)

RGD

NCBI chr 5:103,599,038...103,599,143

G

matrix metallopeptidase 2

severity

protein:increased expression:brain (human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:16598420 PMID:7616276

NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870

G

matrix metallopeptidase 7

severity

protein:increased expression:brain (human)

RGD

NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902

G

matrix metallopeptidase 9

severity
treatment

protein:increased expression:brain (human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:16598420 PMID:7616276 PMID:12439751

RGD:7207145, RGD:8547973

NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120

G

mutS homolog 2

ClinVar Annotator: match by term: Glioblastoma

NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938

G

mechanistic target of rapamycin kinase

CTD Direct Evidence: marker/mechanism

NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311

G

MYC proto-oncogene, bHLH transcription factor

CTD Direct Evidence: marker/mechanism

NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630

G

nuclear receptor co-repressor 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032

G

N-myc downstream regulated 1

CTD Direct Evidence: marker/mechanism

NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880

G

NDRG family member 4

mRNA, protein:decreased expression:brain

RGD

NCBI chr19:9,351,408...9,387,398
Ensembl chr19:9,351,404...9,386,914

G

neurofibromin 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658

G

NFKB inhibitor alpha

treatment

human cell line in a mouse model

RGD

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

notch receptor 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531

G

notch receptor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088

G

notch receptor 3

CTD Direct Evidence: marker/mechanism

NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025

G

NRAS proto-oncogene, GTPase

DNA:mutation:cds:c.35G>A, p.G12D(human)
DNA:amplication::

RGD

PMID:15517309 PMID:11351043

RGD:13702875, RGD:13702876

NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626

G

platelet derived growth factor subunit B

RGD

NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984

G

platelet derived growth factor receptor beta

treatment

RGD

NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843

G

podoplanin

RGD

NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656

G

platelet and endothelial cell adhesion molecule 1

RGD

NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116

G

placental growth factor

disease_progression

RGD

NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

ClinVar Annotator: match by term: Glioblastoma | ClinVar Annotator: match by term: Glioblastoma multiforme
ClinVar Annotator: match by term: Glioblastoma | ClinVar Annotator: match by term: Glioblastoma, somatic

PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More...

NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta

disease_progression

RGD

PMID:26956052 PMID:21188471

RGD:11343921, RGD:13782050

NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta

disease_progression

RGD

NCBI chr 5:160,094,952...160,142,962
Ensembl chr 5:160,094,952...160,120,930

G

Pim-1 proto-oncogene, serine/threonine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174

G

PML nuclear body scaffold

CTD Direct Evidence: marker/mechanism

NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971

G

DNA polymerase kappa

CTD Direct Evidence: marker/mechanism

NCBI chr 2:27,822,228...27,882,331
Ensembl chr 2:27,822,679...27,882,313

G

protection of telomeres 1

ClinVar Annotator: match by term: Glioblastoma, somatic

NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042

G

peroxisome proliferator-activated receptor gamma

ClinVar Annotator: match by term: Glioblastoma, somatic

PMID:9467001 PMID:10381354 PMID:10523018 PMID:10690291 PMID:10851250 More...

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

G

parkin RBR E3 ubiquitin protein ligase

CTD Direct Evidence: marker/mechanism

NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555

G

prominin 1

CTD Direct Evidence: marker/mechanism

PMID:18679414 PMID:18829568 PMID:19718438

NCBI chr14:66,989,545...67,094,534
Ensembl chr14:66,990,160...67,094,527

G

phosphatase and tensin homolog

RGD

NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838

G

prostaglandin-endoperoxide synthase 1

disease_progression

protein:increased expression:microglia, macrophage,

RGD

PMID:11121536 PMID:10229132

RGD:5688245, RGD:5688250

NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586

G

prostaglandin-endoperoxide synthase 2

disease_progression

protein:increased expression:endothelial cell

RGD

PMID:11121536 PMID:10229132

RGD:5688245, RGD:5688250

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

protein tyrosine kinase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783

G

pleiotrophin

protein:increased expression:brain (human)

RGD

NCBI chr 4:65,293,731...65,375,572
Ensembl chr 4:65,293,734...65,375,456

G

protein tyrosine phosphatase, receptor type, B

treatment

human cells in mouse model
protein:increased expression:brain (human)

RGD

PMID:16489031 PMID:15831233 PMID:14692702

RGD:151660504, RGD:151664746, RGD:151660507

NCBI chr 7:51,953,375...52,034,751
Ensembl chr 7:51,930,015...52,034,748

G

RB transcriptional corepressor 1

severity

DNA:hypermethylation:promoter:

RGD

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

G

reversion-inducing-cysteine-rich protein with kazal motifs

CTD Direct Evidence: therapeutic

NCBI chr 5:58,102,961...58,169,516
Ensembl chr 5:58,102,981...58,169,502

G

ribosomal protein L35A

mRNA:increased expression:brain (human)

RGD

NCBI chr11:67,726,031...67,729,953
Ensembl chr11:67,726,032...67,729,942
Ensembl chr 5:67,726,032...67,729,942
Ensembl chr 6:67,726,032...67,729,942
Ensembl chr 7:67,726,032...67,729,942
Ensembl chr12:67,726,032...67,729,942

G

ribosomal protein L5

DNA:mutations:multiple (human)

RGD

NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290

G

RUNX family transcription factor 1

CTD Direct Evidence: marker/mechanism

NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542

G

RUNX family transcription factor 3

CTD Direct Evidence: marker/mechanism

NCBI chr 5:147,360,587...147,419,161
Ensembl chr 5:147,360,994...147,419,156

G

septin 14

CTD Direct Evidence: marker/mechanism

NCBI chr12:26,975,283...27,005,588
Ensembl chr12:26,975,344...26,998,299

G

serpin family G member 1

treatment

RGD

NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034

G

solute carrier family 22 member 22

CTD Direct Evidence: marker/mechanism

NCBI chr 7:88,720,425...88,750,111
Ensembl chr 7:88,720,427...88,750,111

G

solute carrier family 7 member 5

disease_progression

RGD

NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823

G

SLX4 structure-specific endonuclease subunit

ClinVar Annotator: match by term: Glioblastoma multiforme

NCBI chr10:11,526,623...11,549,313
Ensembl chr10:11,528,424...11,549,295

G

serrate, RNA effector molecule

CTD Direct Evidence: marker/mechanism

NCBI chr12:19,392,578...19,406,098
Ensembl chr12:19,392,625...19,406,095

G

signal transducer and activator of transcription 3

disease_progression

mRNA, protein:increased expression:brain (human)

RGD

NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057

G

signal transducer and activator of transcription 5A

disease_progression
treatment

mRNA, protein:increased expression:brain (human)
human cells in mouse model

RGD

PMID:31783691 PMID:31783691

RGD:151667907, RGD:151667907

NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866

G

SUZ12 polycomb repressive complex 2 subunit

CTD Direct Evidence: marker/mechanism

NCBI chr10:64,967,035...65,012,916
Ensembl chr10:64,966,967...65,012,738

G

testin LIM domain protein

CTD Direct Evidence: marker/mechanism

NCBI chr 4:45,365,304...45,403,829
Ensembl chr 4:45,365,285...45,403,829

G

transglutaminase 2

CTD Direct Evidence: marker/mechanism|therapeutic

PMID:16170020 PMID:17099729

NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981

G

transmembrane protein 135

CTD Direct Evidence: marker/mechanism

NCBI chr 1:143,006,343...143,279,824
Ensembl chr 1:143,006,344...143,221,171

G

tenascin C

RGD

NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624

G

TNF superfamily member 10

CTD Direct Evidence: therapeutic

NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135

G

tumor protein p53

ClinVar Annotator: match by term: Glioblastoma, somatic

MouseDO
ClinVar

PMID:1467311 PMID:1565143 PMID:1565144 PMID:1591732 PMID:1631137 More...

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

G

tumor protein p53 binding protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822

G

tRNA methyltransferase 11 homolog

CTD Direct Evidence: marker/mechanism

NCBI chr 1:27,054,437...27,109,765
Ensembl chr 1:27,054,420...27,201,610

G

vascular endothelial growth factor A

CTD Direct Evidence: marker/mechanism

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

G

WT1 transcription factor

CTD Direct Evidence: marker/mechanism

NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643

G

X-ray repair cross complementing 1

susceptibility

DNA:SNP:exon 10: p.R399Q (human)

NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701

G

zinc finger and BTB domain containing 7a

CTD Direct Evidence: marker/mechanism

NCBI chr 7:8,561,015...8,578,243
Ensembl chr 7:8,563,779...8,576,539

glioblastoma proneural subtype

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

RB transcriptional corepressor 1

RNA:decreased expression:brain:

RGD

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

gliosarcoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

C-C motif chemokine ligand 2

severity

mouse gene in a rat model

RGD

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

cytochrome P450, family 2, subfamily b, polypeptide 3

CTD Direct Evidence: therapeutic

PMID:9766669 PMID:11389073

NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, subfamily 2, polypeptide 11

CTD Direct Evidence: therapeutic

NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066

G

plasminogen activator, urokinase

severity

mouse gene in rat model

RGD

NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775

G

cytochrome p450 oxidoreductase

CTD Direct Evidence: therapeutic

NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245

G

prostaglandin-endoperoxide synthase 1

protein:increased expression:microglia, macrophage,

RGD

NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586

G

prostaglandin-endoperoxide synthase 2

protein:increased expression:endothelial cell

RGD

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

vascular endothelial growth factor A

CTD Direct Evidence: marker/mechanism

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

high grade ependymoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

partner and localizer of BRCA2

ClinVar Annotator: match by term: Malignant ependymoma

PMID:21285249 PMID:25085752 PMID:25741868 PMID:26315354 PMID:26467025 More...

NCBI chr 1:176,665,076...176,689,053
Ensembl chr 1:176,665,076...176,688,990

G

RUNX family transcription factor 1

ClinVar Annotator: match by term: Malignant ependymoma

PMID:23753029 PMID:25741868 PMID:26580448 PMID:28492532 PMID:28801348 More...

NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542

high grade glioma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP-binding cassette, sub-family B member 1B

RGD

NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199

G

activin A receptor type 1

CTD Direct Evidence: marker/mechanism

PMID:24705251 PMID:24705252 PMID:24705254

NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241

G

adhesion G protein-coupled receptor A2

ClinVar Annotator: match by term: Ependymoma

NCBI chr16:64,932,964...64,971,433
Ensembl chr16:64,933,315...64,971,483

G

AKT serine/threonine kinase 2

protein:increased expression:cytoplasm (human)

RGD

PMID:19330838 PMID:19330838

RGD:2313297, RGD:2313297

NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817

G

angiomotin-like 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:11,348,651...11,467,564
Ensembl chr 8:11,353,674...11,467,573

G

angiopoietin 2

protein:increased expression:brain (rat)

RGD

NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804

G

APC regulator of WNT signaling pathway

ClinVar Annotator: match by term: Malignant glioma

NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696

G

apolipoprotein D

CTD Direct Evidence: marker/mechanism

NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305

G

A-Raf proto-oncogene, serine/threonine kinase

disease_progression

RGD

NCBI chr X:1,227,392...1,292,356
Ensembl chr X:1,227,392...1,239,073

G

amphiregulin

RGD

NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535

G

Rho GTPase activating protein 32

ClinVar Annotator: match by term: Ependymoma

NCBI chr 8:30,421,269...30,681,653
Ensembl chr 8:30,421,515...30,678,454

G

AT-rich interaction domain 1B

ClinVar Annotator: match by term: Astrocytoma

NCBI chr 1:45,567,991...45,923,644
Ensembl chr 1:45,563,623...45,923,493

G

assembly factor for spindle microtubules

disease_progression

mRNA:increased expression:brain:

RGD

NCBI chr13:51,074,849...51,123,755
Ensembl chr13:51,074,849...51,123,755

G

activating transcription factor 5

CTD Direct Evidence: marker/mechanism

NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707

G

autophagy related 7

treatment

RGD

NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593

G

ATM serine/threonine kinase

ClinVar Annotator: match by term: Malignant glioma

PMID:8659541 PMID:8808599 PMID:9000145 PMID:9463314 PMID:10330348 More...

NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437

G

ATPase Na+/K+ transporting subunit beta 2

CTD Direct Evidence: marker/mechanism

NCBI chr10:54,318,698...54,324,933
Ensembl chr10:54,318,701...54,324,933

G

ATRX, chromatin remodeler

DNA:mutations: :multiple
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:23583981 PMID:24705251 PMID:23104868

NCBI chr X:70,850,981...70,997,330
Ensembl chr X:70,850,981...70,997,330

G

BCL2-associated agonist of cell death

protein:increased phosphorylation:brain (rat)

RGD

NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823

G

Btg3 associated nuclear protein

ClinVar Annotator: match by term: Ependymoma

NCBI chr19:50,007,710...50,082,742
Ensembl chr19:50,007,881...50,082,738

G

BRCA1 associated deubiquitinase 1

ClinVar Annotator: match by term: Astrocytoma

NCBI chr16:6,446,709...6,455,535
Ensembl chr16:6,446,709...6,455,535

G

BarH-like homeobox 1

protein:increased expression:brain:

RGD

NCBI chr 3:12,241,327...12,248,649
Ensembl chr 3:12,241,327...12,248,649

G

brevican

severity

protein:increased expression:brain:

RGD

PMID:12799382 PMID:23253190 PMID:16061654 PMID:11585735

RGD:14392782, RGD:14392804, RGD:14392797, RGD:14392783

NCBI chr 2:173,454,479...173,467,717
Ensembl chr 2:173,454,482...173,467,460

G

bradykinin receptor B2

mRNA:increased expression:brain

RGD

NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497

G

baculoviral IAP repeat-containing 5

protein:increased expression:brain

RGD

NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380

G

BMI1 proto-oncogene, polycomb ring finger

CTD Direct Evidence: marker/mechanism

NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690

G

B-Raf proto-oncogene, serine/threonine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463

G

BRCA2, DNA repair associated

ClinVar Annotator: match by term: Glioma susceptibility 3
ClinVar Annotator: match by term: Glioma susceptibility 3 | ClinVar Annotator: match by term: Glioma susceptibility 9
ClinVar Annotator: match by term: Glioma susceptibility 1 | ClinVar Annotator: match by term: Glioma susceptibility 3 | ClinVar Annotator: match by term: Glioma susceptibility 9
ClinVar Annotator: match by term: Brainstem glioma | ClinVar Annotator: match by term: Glioma susceptibility 3 | ClinVar Annotator: match by term: Glioma susceptibility 9 | ClinVar Annotator: match by term: Malignant glioma
ClinVar Annotator: match by term: Brainstem glioma | ClinVar Annotator: match by term: Glioma susceptibility 1 | ClinVar Annotator: match by term: Glioma susceptibility 3 | ClinVar Annotator: match by term: Glioma susceptibility 9
CTD Direct Evidence: marker/mechanism

ClinVar
OMIM
CTD

PMID:186727 PMID:251866 PMID:278235 PMID:1772447 PMID:2200631 More...

NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567

G

bromodomain containing 7

protein:increased expression:brain:

RGD

NCBI chr19:18,708,792...18,737,497
Ensembl chr19:18,709,022...18,737,494

G

complement C3

treatment

RGD

NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429

G

similar to human chromosome 11 open reading frame 65

ClinVar Annotator: match by term: Malignant glioma

PMID:8659541 PMID:8808599 PMID:9000145 PMID:9463314 PMID:10330348 More...

NCBI chr 8:53,796,033...53,825,277
Ensembl chr 8:53,796,366...53,824,748

G

calcium voltage-gated channel auxiliary subunit gamma 2

ClinVar Annotator: match by term: Ependymoma

NCBI chr 7:109,572,838...109,698,516
Ensembl chr 7:109,574,459...109,697,227

G

calcium/calmodulin-dependent protein kinase II alpha

disease_progression

RGD

NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994

G

calcium/calmodulin-dependent protein kinase II beta

disease_progression

RGD

NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994

G

calcium/calmodulin-dependent protein kinase kinase 2

disease_progression

RGD

NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279

G

catalase

CTD Direct Evidence: marker/mechanism

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

caveolin 1

RGD

NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705

G

caveolin 2

RGD

NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244

G

cellular communication network factor 1

exacerbates

human cells in mouse model

RGD

NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484

G

cyclin D1

susceptibility
disease_progression

RGD

PMID:22304571 PMID:21844184 PMID:21844184

RGD:13681930, RGD:13702091, RGD:13702091

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

G

C-C motif chemokine receptor 4

CTD Direct Evidence: marker/mechanism

NCBI chr 8:114,176,291...114,182,033
Ensembl chr 8:114,176,974...114,178,056

G

CD40 molecule

treatment

RGD

NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534

G

Cd80 molecule

RGD

NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030

G

cyclin-dependent kinase 4

disease_progression

RGD

PMID:23761023 PMID:21844184

RGD:13702090, RGD:13702091

NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403

G

cyclin-dependent kinase 6

severity

DNA:amplification:

RGD

PMID:22736304 PMID:9102208

RGD:13702093, RGD:13702094

NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634

G

cyclin-dependent kinase inhibitor 1A

severity
treatment

DNA:hypermethylation:promoter:

RGD

PMID:20844987 PMID:9144534 PMID:18791688

RGD:13702125, RGD:13702129, RGD:13702128

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 2A

disease_progression

DNA:deletions
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:15814359 PMID:19578367 PMID:11314047

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

G

cyclin-dependent kinase inhibitor 2B

CTD Direct Evidence: marker/mechanism

PMID:19578366 PMID:19578367

NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050

G

chromatin assembly factor 1 subunit A

susceptibility

DNA:SNP:intron:rs243356(human)

RGD

NCBI chr 9:873,953...900,701
Ensembl chr 9:874,051...900,654

G

chromatin assembly factor 1 subunit B

disease_progression

protein:increased expression:brain:

RGD

NCBI chr11:33,200,894...33,221,076
Ensembl chr11:33,200,981...33,221,070

G

checkpoint kinase 2

ClinVar Annotator: match by term: Astrocytoma

PMID:10617473 PMID:11053450 PMID:11479205 PMID:11719428 PMID:11967536 More...

NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286

G

chitinase 3 like 1

CTD Direct Evidence: marker/mechanism

NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787

G

chloride voltage-gated channel 2

CTD Direct Evidence: marker/mechanism

NCBI chr11:80,197,741...80,211,657
Ensembl chr11:80,198,153...80,211,657

G

chloride voltage-gated channel 3

CTD Direct Evidence: marker/mechanism

NCBI chr16:29,127,152...29,200,133
Ensembl chr16:29,127,419...29,200,119

G

chloride voltage-gated channel 5

CTD Direct Evidence: marker/mechanism

NCBI chr X:15,185,380...15,339,977
Ensembl chr X:15,185,451...15,334,264

G

contactin 2

severity

mRNA, protein:increased expression:brain (human)

RGD

NCBI chr13:43,942,868...43,975,973
Ensembl chr13:43,947,265...43,975,887

G

ciliogenesis and planar polarity effector complex subunit 1

ClinVar Annotator: match by term: Astrocytoma

PMID:25741868 PMID:28492532

NCBI chr 2:57,269,195...57,369,580
Ensembl chr 2:57,268,884...57,369,500

G

colony stimulating factor 1

RGD

NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704

G

cathepsin B

RGD

NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500

G

C-X-C motif chemokine receptor 3

RGD

NCBI chr X:66,844,318...66,846,969
Ensembl chr X:66,844,318...66,846,969

G

cytochrome P450, family 2, subfamily b, polypeptide 1

CTD Direct Evidence: therapeutic

NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052

G

cytochrome P450, family 2, subfamily e, polypeptide 1

DNA:snp:promoter:c.-1053C>T (human)

RGD

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

G

decorin

disease_progression

RGD

NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270

G

doublecortin

disease_progression
treatment

RGD

PMID:17178868 PMID:21477071 PMID:19681167

RGD:12904748, RGD:12904761, RGD:12904754

NCBI chr X:107,430,767...107,573,612
Ensembl chr X:107,430,767...107,507,476

G

discoidin domain receptor tyrosine kinase 1

severity

mRNA, protein:increased expression:brain (human)

RGD

NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468

G

DEP domain containing 5, GATOR1 subcomplex subunit

ClinVar Annotator: match by term: Ependymoma

NCBI chr14:77,732,297...77,862,924
Ensembl chr14:77,732,297...77,862,794

G

dicer 1 ribonuclease III

ClinVar Annotator: match by term: Pediatric high-grade glioma

PMID:25741868 PMID:26526666 PMID:28492532 PMID:29708584

NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965

G

delta like non-canonical Notch ligand 1

RGD

NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522

G

delta like canonical Notch ligand 4

ameliorates

RGD

NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931

G

Dmx-like 1

CTD Direct Evidence: marker/mechanism

NCBI chr18:42,993,292...43,163,457
Ensembl chr18:42,993,340...43,163,456

G

E2F transcription factor 1

severity

RGD

NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361

G

E2F transcription factor 3

disease_progression

RGD

NCBI chr17:34,601,756...34,679,139
Ensembl chr17:34,601,830...34,676,253

G

EGF containing fibulin extracellular matrix protein 1

protein:increased expression:brain:

RGD

NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018

G

elongation factor like GTPase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:136,638,527...136,763,518
Ensembl chr 1:136,638,527...136,763,518

G

epidermal growth factor

susceptibility

DNA:polymorphism:promoter:+61A>G(human)
DNA:polymorphism:promoter:GG genotypes were associated with increased risk.

RGD

PMID:22106858 PMID:17473192

RGD:13702473, RGD:13702474

NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064

G

epidermal growth factor receptor

treatment

protein:alternative form:tumor (human)

RGD

PMID:7606735 PMID:10616092

RGD:5131512, RGD:38599219

NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382

G

EH-domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:203,579,850...203,602,226
Ensembl chr 1:203,579,869...203,602,212

G

ectonucleoside triphosphate diphosphohydrolase 2

RGD

NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866

G

EPH receptor A5

ClinVar Annotator: match by term: Astrocytoma

NCBI chr14:23,653,393...24,020,129
Ensembl chr14:23,653,393...24,017,317

G

erythropoietin

RGD

NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946

G

erythropoietin receptor

RGD

NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257

G

erb-b2 receptor tyrosine kinase 2

ClinVar Annotator: match by term: Glioma susceptibility 1
CTD Direct Evidence: marker/mechanism

OMIM
ClinVar
CTD

NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078

G

ERCC excision repair 1, endonuclease non-catalytic subunit

susceptibility

DNA:snp:3'utr:c.8092C>A (human) (rs3212986)

RGD

NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963

G

ERCC excision repair 2, TFIIH core complex helicase subunit

susceptibility

RGD

NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102

G

ERCC excision repair 5, endonuclease

susceptibility

DNA:SNP:cd: p.D1558H (rs17655) (human)

RGD

NCBI chr 9:46,309,477...46,354,478
Ensembl chr 9:46,309,389...46,354,472

G

coagulation factor II, thrombin

treatment

RGD

NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486

G

family with sequence similarity 107, member A

CTD Direct Evidence: marker/mechanism

NCBI chr15:16,608,362...16,630,398
Ensembl chr15:16,607,205...16,630,396

G

FA complementation group A

ClinVar Annotator: match by term: Pediatric high-grade glioma

NCBI chr19:51,304,126...51,362,586
Ensembl chr19:51,304,021...51,362,527

G

FA complementation group B

ClinVar Annotator: match by term: Glioma susceptibility 1

PMID:15502827 PMID:16199547 PMID:23613520 PMID:25741868 PMID:28492532

NCBI chr X:29,403,771...29,420,484
Ensembl chr X:29,403,771...29,420,192

G

Fas cell surface death receptor

severity

mouse gene in a rat model

RGD

NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591

G

F-box and WD repeat domain containing 7

CTD Direct Evidence: marker/mechanism

NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941

G

fibroblast growth factor 2

CTD Direct Evidence: therapeutic

NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221

G

Fibroblast growth factor receptor 1

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Astrocytoma

NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350

G

Fms related receptor tyrosine kinase 3 ligand

treatment

RGD

NCBI chr 1:95,615,056...95,620,463
Ensembl chr 1:95,609,370...95,620,463

G

ferritin heavy chain 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424

G

glial cell derived neurotrophic factor

CTD Direct Evidence: marker/mechanism

NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209

G

gap junction protein, alpha 1

RGD

NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582

G

galactosidase, beta 1

ClinVar Annotator: match by term: Ependymoma

NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127

G

gon-4 like

ClinVar Annotator: match by term: Ependymoma

NCBI chr 2:174,233,461...174,306,636
Ensembl chr 2:174,233,461...174,306,634

G

glutathione S-transferase mu 1

severity

RGD

NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411

G

glutathione S-transferase mu 3

DNA: deletion: intron 6

RGD

NCBI chr 2:195,590,450...195,612,578
Ensembl chr 2:195,607,289...195,612,475

G

glutathione S-transferase, mu 5

DNA: deletion: intron 6

NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553

G

glutathione S-transferase pi 1

susceptibility

DNA:polymorphism:exon:p.I105V (rs1695) (human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:16899598 PMID:15006924

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

H3.3 histone A

CTD Direct Evidence: marker/mechanism

PMID:22286216 PMID:23583981

NCBI chr13:92,533,289...92,544,902
Ensembl chr13:92,533,298...92,544,908

G

histone deacetylase 3

disease_progression

mRNA,protein:increased expression:brain:
ClinVar Annotator: match by term: Ependymoma

NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856

G

helicase, lymphoid specific

severity

RGD

NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844

G

hepatocyte growth factor

disease_progression

protein:increased expression:brain:

RGD

NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409

G

high mobility group box 1

treatment

RGD

NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565

G

high mobility group nucleosome binding domain 5

CTD Direct Evidence: marker/mechanism

NCBI chr X:74,085,871...74,094,488
Ensembl chr X:74,085,875...74,094,441
Ensembl chr 1:74,085,875...74,094,441

G

homeobox D11

CTD Direct Evidence: marker/mechanism

NCBI chr 3:59,584,840...59,587,257
Ensembl chr 3:59,585,039...59,586,783

G

HRas proto-oncogene, GTPase

CTD Direct Evidence: marker/mechanism

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2

ClinVar Annotator: match by term: Ependymoma

NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852

G

heat shock protein family A (Hsp70) member 5

protein:increased expression

RGD

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

isocitrate dehydrogenase (NADP(+)) 1

susceptibility

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Glioma susceptibility 1 | ClinVar Annotator: match by term: IDH1-related condition
ClinVar Annotator: match by term: Brainstem glioma | ClinVar Annotator: match by term: Glioma susceptibility 1 | ClinVar Annotator: match by term: Glioma susceptibility 9 | ClinVar Annotator: match by term: IDH1-related condition
ClinVar Annotator: match by term: Brainstem glioma | ClinVar Annotator: match by term: Ependymoma | ClinVar Annotator: match by term: Glioma susceptibility 1 | ClinVar Annotator: match by term: Glioma susceptibility 9

CTD
ClinVar
OMIM

PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:19901110 More...

NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708

G

interferon gamma

RGD

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

insulin-like growth factor 1

severity

protein:increased expression:serum:

RGD

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

G

insulin-like growth factor 1 receptor

DNA: SNP: : rs2272037 or rs2016347

RGD

NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777

G

insulin-like growth factor binding protein 3

severity

protein:increased expression:serum:

RGD

NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083

G

interleukin 10

susceptibility

DNA:SNP: :rs1800896 (human)

RGD

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

G

interleukin 12A

CTD Direct Evidence: therapeutic

NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734

G

interleukin 12B

CTD Direct Evidence: therapeutic

NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903

G

interleukin 18

treatment

RGD

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

G

interleukin 2

treatment

RGD

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

interleukin 4

treatment

RGD

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

G

interleukin 7

RGD

NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075

G

ISG15 ubiquitin-like modifier

CTD Direct Evidence: marker/mechanism

NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435

G

lysine acetyltransferase 6B

ClinVar Annotator: match by term: Ependymoma

NCBI chr15:2,638,885...2,811,977
Ensembl chr15:2,639,200...2,812,316

G

lysine demethylase 5B

disease_progression

RGD

PMID:25450384 PMID:25450384

RGD:13702126, RGD:13702126

NCBI chr13:46,001,589...46,073,868
Ensembl chr13:46,002,542...46,073,872

G

kinase insert domain receptor

disease_progression
severity

RGD

PMID:20501615 PMID:10506722

RGD:5684393, RGD:5684425

NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018

G

kelch-like family member 21

ClinVar Annotator: match by term: Ependymoma

NCBI chr 5:162,514,888...162,523,545
Ensembl chr 5:162,514,765...162,523,545

G

killin, p53-regulated DNA replication inhibitor

ClinVar Annotator: match by term: Glioma susceptibility 2

PMID:25741868 PMID:26467025 PMID:27535533

G

lysine methyltransferase 2D

ClinVar Annotator: match by term: Astrocytoma

NCBI chr 7:129,980,744...130,022,088
Ensembl chr 7:129,962,887...130,020,325

G

KRAS proto-oncogene, GTPase

severity

RGD

PMID:22207524 PMID:19435821

RGD:13702477, RGD:13702860

NCBI chr 4:178,185,418...178,218,484

G

kringle containing transmembrane protein 2

ClinVar Annotator: match by term: Ependymoma

NCBI chr10:12,763,345...12,767,622
Ensembl chr10:12,763,397...12,767,854

G

large tumor suppressor kinase 1

ClinVar Annotator: match by term: Ependymoma

NCBI chr 1:2,160,411...2,193,640
Ensembl chr 1:2,160,411...2,193,640

G

leucine zipper and EF-hand containing transmembrane protein 1

ClinVar Annotator: match by term: Ependymoma

NCBI chr14:76,942,647...76,982,220
Ensembl chr14:76,942,729...76,984,904

G

galectin 3

disease_progression

RGD

NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025

G

DNA ligase 4

DNA:SNP: :rs1805388 (human)

RGD

NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040

G

lymphotoxin alpha

treatment

RGD

NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859

G

leucine zipper like post translational regulator 1

ClinVar Annotator: match by term: Pediatric high-grade glioma

NCBI chr11:83,487,717...83,503,896
Ensembl chr11:83,487,717...83,503,633

G

mitogen activated protein kinase kinase 1

RGD

NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147

G

mitogen-activated protein kinase kinase kinase kinase 3

ClinVar Annotator: match by term: Ependymoma

NCBI chr 6:14,276,623...14,446,321
Ensembl chr 6:14,277,121...14,446,334

G

mitogen activated protein kinase 3

RGD

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

midkine

CTD Direct Evidence: marker/mechanism

NCBI chr 3:77,901,134...77,903,997
Ensembl chr 3:77,901,158...77,903,130

G

menin 1

ClinVar Annotator: match by term: Ependymoma

NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871

G

MET proto-oncogene, receptor tyrosine kinase

protein:increased expression:brain, glioma (rat)

RGD

NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876

G

O-6-methylguanine-DNA methyltransferase

CTD Direct Evidence: marker/mechanism

PMID:16033832 PMID:16899598 PMID:19901110

NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756

G

marker of proliferation Ki-67

RGD

NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762

G

matrix metallopeptidase 2

treatment

RGD

NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870

G

mutS homolog 2

ClinVar Annotator: match by term: Ependymoma
ClinVar Annotator: match by term: Ependymoma | ClinVar Annotator: match by term: Malignant glioma

PMID:11726306 PMID:15849733 PMID:16395668 PMID:17101317 PMID:25741868 More...

NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4

ClinVar Annotator: match by term: Ependymoma

NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
Ensembl chr MT:10,160...11,537

G

mechanistic target of rapamycin kinase

severity

RGD

NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311

G

MYB proto-oncogene, transcription factor

CTD Direct Evidence: marker/mechanism

PMID:23583981 PMID:26829751

NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057

G

MYB proto-oncogene like 1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183

G

myosin light chain kinase

CTD Direct Evidence: marker/mechanism

NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261

G

NAD synthetase 1

susceptibility

RGD

NCBI chr 1:198,981,559...199,009,853
Ensembl chr 1:198,981,604...199,009,869

G

nibrin

ClinVar Annotator: match by term: Pediatric high-grade glioma

PMID:11325820 PMID:14559852 PMID:15338273 PMID:16474176 PMID:16810201 More...

NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150

G

NDRG family member 4

disease_progression

protein:decreased expression:brain

RGD

NCBI chr19:9,351,408...9,387,398
Ensembl chr19:9,351,404...9,386,914

G

neuroepithelial cell transforming 1

ClinVar Annotator: match by term: Ependymoma

NCBI chr17:66,341,251...66,370,445
Ensembl chr17:66,340,728...66,370,441

G

neurofibromin 1

disease_progression

CTD Direct Evidence: marker/mechanism
DNA:mutations: :

CTD
RGD

PMID:25119042 PMID:26190195

NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658

G

NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor

ClinVar Annotator: match by term: Ependymoma

NCBI chr14:79,627,399...79,710,709
Ensembl chr14:79,627,399...79,710,667

G

nitric oxide synthase 3

protein:increased expression:blood vessel endothelial cell

RGD

NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166

G

neurotrophic receptor tyrosine kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770

G

neurotrophic receptor tyrosine kinase 2

CTD Direct Evidence: marker/mechanism

NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136

G

neurotrophic receptor tyrosine kinase 3

CTD Direct Evidence: marker/mechanism

NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286

G

OTU deubiquitinase 5

ClinVar Annotator: match by term: Ependymoma

NCBI chr X:14,626,173...14,659,331
Ensembl chr X:14,626,164...14,659,573

G

POZ (BTB) and AT hook containing zinc finger 1

ClinVar Annotator: match by term: Ependymoma

NCBI chr14:78,154,590...78,173,032
Ensembl chr14:78,152,516...78,173,032

G

protein-L-isoaspartate (D-aspartate) O-methyltransferase 1

mRNA:decreased expression:brain:

RGD

NCBI chr 1:2,111,756...2,160,354
Ensembl chr 1:2,111,763...2,159,201

G

PDGFA associated protein 1

severity

RGD

NCBI chr12:9,470,652...9,480,880
Ensembl chr12:9,470,574...9,535,374

G

platelet derived growth factor subunit A

in a mouse model

RGD

NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497

G

platelet derived growth factor subunit B

severity

RGD

PMID:27448842 PMID:21677873 PMID:26945107

RGD:13702895, RGD:13702897, RGD:13702896

NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984

G

pleckstrin homology-like domain, family B, member 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:45,003,543...45,051,541
Ensembl chr 8:45,003,538...45,051,522

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

ClinVar Annotator: match by term: Brainstem glioma | ClinVar Annotator: match by term: Glioma susceptibility 9
ClinVar Annotator: match by term: Brainstem glioma | ClinVar Annotator: match by term: Ependymoma | ClinVar Annotator: match by term: Glioma susceptibility 9

PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370