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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Reperfusion Injury
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Accession:DOID:9004009 term browser browse the term
Definition:Adverse functional, metabolic, or structural changes in ischemic tissues resulting from the restoration of blood flow to the tissue (REPERFUSION), including swelling; HEMORRHAGE; NECROSIS; and damage from FREE RADICALS. The most common instance is MYOCARDIAL REPERFUSION INJURY.
Synonyms:exact_synonym: Ischemia Reperfusion Injury;   Ischemia-Reperfusion Injuries;   Reperfusion Damage;   Reperfusion Damages;   Reperfusion Injuries
 primary_id: MESH:D015427
 xref: EFO:0002687


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Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A EXP CTD Direct Evidence: marker/mechanism CTD PMID:22749977 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Abcc5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 ISO mRNA, protein:increased expression:brain, neuron RGD PMID:16997484 RGD:2301088 NCBI chr16:20,150,053...20,245,178
Ensembl chr16:20,150,053...20,245,144 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) ISO mRNA, protein:increased expression, altered localization:small intestine RGD PMID:18451542 RGD:2315580 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661 		JBrowse link
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 ISO RGD PMID:20436217 RGD:2325213 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790 		JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 ISO mRNA:increased expression:hippocampal granule cell RGD PMID:19647005 RGD:2315956 NCBI chr17:93,506,448...93,513,967
Ensembl chr17:93,506,445...93,513,965 		JBrowse link
G Adcyap1r1 adenylate cyclase activating polypeptide 1 receptor 1 ISO mRNA:decreased expression:dentate gyrus (rat) RGD PMID:19647005 RGD:2315956 NCBI chr 6:55,428,486...55,478,440
Ensembl chr 6:55,428,963...55,478,436 		JBrowse link
G Adgrl1 adhesion G protein-coupled receptor L1 ISO RGD PMID:12225880 RGD:2314400 NCBI chr 8:84,626,598...84,668,583
Ensembl chr 8:84,626,734...84,668,583 		JBrowse link
G Adgrl3 adhesion G protein-coupled receptor L3 ISO RGD PMID:12225880 RGD:2314400 NCBI chr 5:81,167,600...81,980,556
Ensembl chr 5:81,167,985...81,972,980 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO associated with Non-alcoholic Fatty Liver Disease; RGD PMID:18098300 RGD:5686804 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778 		JBrowse link
G Adm adrenomedullin ISO protein:increased expression:plasma: RGD PMID:17263982 RGD:7364988 NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027 		JBrowse link
G Adora2a adenosine A2a receptor ISO CTD Direct Evidence: therapeutic CTD
RGD		 PMID:27757725 PMID:17937935 RGD:4890367 NCBI chr10:75,152,711...75,170,626
Ensembl chr10:75,152,711...75,170,618 		JBrowse link
G Adora2b adenosine A2b receptor ISO CTD Direct Evidence: therapeutic CTD PMID:27757725 NCBI chr11:62,139,810...62,157,278
Ensembl chr11:62,139,810...62,157,279 		JBrowse link
G Adrb1 adrenergic receptor, beta 1 ISO RGD PMID:20451506 RGD:5129116 NCBI chr19:56,710,549...56,713,582
Ensembl chr19:56,710,631...56,721,545 		JBrowse link
G Adrb2 adrenergic receptor, beta 2 ISO RGD PMID:14630341 PMID:18336819 RGD:1598754, RGD:4145097 NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030 		JBrowse link
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) ISO CTD Direct Evidence: marker/mechanism CTD PMID:23875703 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 ISO RGD PMID:22920387 RGD:6903870 NCBI chr  X:21,350,863...21,355,072
Ensembl chr  X:21,350,783...21,355,403 		JBrowse link
G Aif1 allograft inflammatory factor 1 ISO protein:increased expression:Kupffer cell (rat) RGD PMID:16500929 RGD:2313040 NCBI chr17:35,389,967...35,394,977
Ensembl chr17:35,389,967...35,395,044 		JBrowse link
G Akt1 thymoma viral proto-oncogene 1 IMP RGD PMID:21351045 RGD:5509067 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318 		JBrowse link
G Akt1s1 AKT1 substrate 1 (proline-rich) ISO CTD Direct Evidence: marker/mechanism CTD PMID:16397181 NCBI chr 7:44,498,648...44,504,845
Ensembl chr 7:44,498,415...44,504,845 		JBrowse link
G Alb albumin ISO mRNA, protein:increased expression:brain RGD PMID:20193666 RGD:2325686 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461 		JBrowse link
G Aldoa aldolase A, fructose-bisphosphate ISO RGD PMID:10395295 RGD:1599061 NCBI chr 7:126,394,406...126,399,537
Ensembl chr 7:126,394,406...126,399,923
Ensembl chr 7:126,394,406...126,399,923 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase ISO RGD PMID:15518705 RGD:5509617 NCBI chr11:70,132,283...70,146,206
Ensembl chr11:70,132,283...70,146,179 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase IMP RGD PMID:18635843 RGD:5509608 NCBI chr11:70,234,973...70,279,465
Ensembl chr11:70,234,978...70,242,857 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO protein:increased expression:cerebral hemisphere
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:15266012 PMID:14769366 PMID:19816089 RGD:1626152, RGD:2317531 NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139 		JBrowse link
G Ang angiogenin, ribonuclease, RNase A family, 5 ISO protein:increased expression:brain RGD PMID:19666176 RGD:2325717 NCBI chr14:51,328,607...51,339,462
Ensembl chr14:51,328,607...51,339,466 		JBrowse link
G Angpt1 angiopoietin 1 ISO RGD PMID:19885826 RGD:2316041 NCBI chr15:42,288,063...42,540,373
Ensembl chr15:42,288,119...42,540,373 		JBrowse link
G Aoc3 amine oxidase, copper containing 3 ISO RGD PMID:16339390 RGD:2313821 NCBI chr11:101,221,432...101,230,256
Ensembl chr11:101,221,431...101,232,764 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 ISO RGD PMID:18205898 RGD:2292105 NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632 		JBrowse link
G Apex1 apurinic/apyrimidinic endonuclease 1 ISO protein:increased expression:placenta RGD PMID:18373555 RGD:2315671 NCBI chr14:51,162,406...51,164,645
Ensembl chr14:51,162,425...51,164,596 		JBrowse link
G Aqp4 aquaporin 4 ISO
IDA
IMP		 protein:increased expression:cerebral cortex
mRNA, protein:increased expression:parietal cortex		 RGD PMID:20979759 PMID:21718723 PMID:19806476 PMID:20924629 RGD:5148016, RGD:5684013, RGD:5148037, RGD:5148022 NCBI chr18:15,522,451...15,544,039
Ensembl chr18:15,522,553...15,544,039 		JBrowse link
G Arg1 arginase, liver ISO protein:increased expression:serum (rat) RGD PMID:17023552 RGD:4143185 NCBI chr10:24,791,105...24,803,368
Ensembl chr10:24,791,119...24,803,382 		JBrowse link
G Asl argininosuccinate lyase resistance ISO protein:increased expression:brain, neuron (rat) RGD PMID:17198704 RGD:1599263 NCBI chr 5:130,040,099...130,053,222
Ensembl chr 5:130,040,099...130,058,088 		JBrowse link
G Ass1 argininosuccinate synthetase 1 resistance ISO protein:increased expression:brain, neuron (rat) RGD PMID:17198704 RGD:1599263 NCBI chr 2:31,360,282...31,410,682
Ensembl chr 2:31,360,219...31,410,684 		JBrowse link
G Bad BCL2-associated agonist of cell death ISO protein:altered localization:brain, mitochondria RGD PMID:18347331 RGD:2292679 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267 		JBrowse link
G Bag1 BCL2-associated athanogene 1 ISO RGD PMID:12215270 RGD:2296021 NCBI chr 4:40,936,398...40,948,294
Ensembl chr 4:40,936,398...40,948,294 		JBrowse link
G Bag3 BCL2-associated athanogene 3 ISO protein:increased expression:hippocampus, astrocyte RGD PMID:12061864 RGD:2325848 NCBI chr 7:128,125,307...128,148,705
Ensembl chr 7:128,125,340...128,148,705 		JBrowse link
G Bax BCL2-associated X protein ISO protein:increased expression:brain RGD PMID:18221257 PMID:18083315 RGD:2293026, RGD:2290557 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 ISO CTD Direct Evidence: therapeutic CTD PMID:15449323 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Bdnf brain derived neurotrophic factor ISO mRNA:increased expression:retina RGD PMID:20554625 RGD:4891135 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352 		JBrowse link
G Becn1 beclin 1, autophagy related ISO protein:increased expression:brain RGD PMID:22306244 RGD:6483054 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112 		JBrowse link
G Bid BH3 interacting domain death agonist ISO RGD PMID:19888517 RGD:2317562 NCBI chr 6:120,870,080...120,894,074
Ensembl chr 6:120,868,891...120,893,814 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 ISO protein:increased expression:brain RGD PMID:18159002 RGD:2293126 NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569 		JBrowse link
G Bmp6 bone morphogenetic protein 6 ISO RGD PMID:11245809 RGD:2289024 NCBI chr13:38,529,098...38,684,283
Ensembl chr13:38,529,083...38,684,278 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor, type II (serine/threonine kinase) ISO mRNA:increased expression:dentate gyrus, granule cell RGD PMID:10996456 RGD:5129486 NCBI chr 1:59,802,721...59,917,240
Ensembl chr 1:59,802,559...59,918,173 		JBrowse link
G Bsg basigin ISO protein:increased expression:basal ganglia RGD PMID:16029217 RGD:2289063 NCBI chr10:79,540,192...79,547,813
Ensembl chr10:79,540,325...79,547,803 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 ISO mRNA:increased expression:kidney RGD PMID:9712737 RGD:2289078 NCBI chr 1:134,002,603...134,006,893
Ensembl chr 1:134,002,908...134,006,858 		JBrowse link
G C3 complement component 3 ISO protein:increased expression:intestine RGD PMID:17981193 RGD:5129536 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G C3ar1 complement component 3a receptor 1 ISO RGD PMID:15159277 RGD:5129702 NCBI chr 6:122,824,099...122,833,116
Ensembl chr 6:122,824,097...122,833,120 		JBrowse link
G C5ar1 complement component 5a receptor 1 ISO RGD PMID:15158333 PMID:15159277 RGD:1600597, RGD:5129702 NCBI chr 7:15,980,668...15,993,465
Ensembl chr 7:15,980,668...15,993,465 		JBrowse link
G Casp1 caspase 1 ISO RGD PMID:17845807 RGD:2315890 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290 		JBrowse link
G Casp12 caspase 12 ISO RGD PMID:18273070 RGD:2311461 NCBI chr 9:5,345,419...5,373,034
Ensembl chr 9:5,345,430...5,373,032 		JBrowse link
G Casp3 caspase 3 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:23875703 PMID:18490106 PMID:29568770 RGD:2293311, RGD:13792595 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp6 caspase 6 ISO protein:increased expression, increased activity:small intestine mucosa RGD PMID:15010362 RGD:2301320 NCBI chr 3:129,695,064...129,707,761
Ensembl chr 3:129,695,074...129,707,752 		JBrowse link
G Casp8 caspase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23875703 NCBI chr 1:58,834,398...58,886,662
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Casp9 caspase 9 treatment ISO RGD PMID:29568770 RGD:13792595 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287 		JBrowse link
G Cast calpastatin ISO RGD PMID:11035539 RGD:5509823 NCBI chr13:74,840,485...74,956,993
Ensembl chr13:74,840,487...74,956,929 		JBrowse link
G Cat catalase ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:8215636 PMID:16682413 PMID:23743330 PMID:23875703 PMID:19196076 More... RGD:5130760, RGD:5130200 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Cav1 caveolin 1, caveolae protein ISO protein:increased expression:brain RGD PMID:17293479 RGD:2289123 NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451 		JBrowse link
G Ccl11 chemokine (C-C motif) ligand 11 ISO mRNA:increased expression:aorta RGD PMID:9665468 RGD:4145482 NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781 		JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 treatment ISO Gastric Reperfusion Injury
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:12468449 PMID:15829914 PMID:22611311 RGD:8549744 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Ccl3 chemokine (C-C motif) ligand 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829914 NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181 		JBrowse link
G Ccl5 chemokine (C-C motif) ligand 5 ISO
IEP		 protein:increased expression:gut
protein:increased secretion:lung, secretion (mouse)		 RGD PMID:15542513 PMID:19558673 RGD:2307184, RGD:4891479 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344 		JBrowse link
G Ccnb1 cyclin B1 ISO protein;altered expression:cerebral cortex, hippocampus CA1, neuron RGD PMID:18278459 RGD:2315990 NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078 		JBrowse link
G Ccnd1 cyclin D1 ISO RGD PMID:16718823 RGD:2289145 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
G Ccne1 cyclin E1 ISO protein:decreased expression:liver RGD PMID:17584601 RGD:2289275 NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959 		JBrowse link
G Ccng1 cyclin G1 ISO mRNA, protein:increased expression:brain RGD PMID:9698156 RGD:2316027 NCBI chr11:40,639,379...40,646,044
Ensembl chr11:40,639,379...40,646,138 		JBrowse link
G Ccr1 chemokine (C-C motif) receptor 1 IEP mRNA:increased expression:kidney RGD PMID:20410256 RGD:5688141 NCBI chr 9:123,762,163...123,768,729
Ensembl chr 9:123,762,161...123,768,729 		JBrowse link
G Cd2ap CD2-associated protein ISO RGD PMID:16088078 RGD:1581187 NCBI chr17:43,059,857...43,187,593
Ensembl chr17:43,103,842...43,187,556 		JBrowse link
G Cd36 CD36 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 5:17,986,688...18,093,957
Ensembl chr 5:17,986,688...18,093,799 		JBrowse link
G Cd40 CD40 antigen ISO RGD PMID:12388354 RGD:5508171 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868 		JBrowse link
G Cd40lg CD40 ligand IMP
ISO		 RGD PMID:20659085 PMID:12388354 RGD:5490531, RGD:5508171 NCBI chr  X:56,257,448...56,269,402
Ensembl chr  X:56,257,503...56,269,402 		JBrowse link
G Cd44 CD44 antigen ISO protein:increased expression:kidney
protein:increased expression:testis, macrophage		 RGD PMID:16786159 PMID:16891795 RGD:2289354, RGD:2289369 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010 		JBrowse link
G Cd55 CD55 molecule, decay accelerating factor for complement ISO RGD PMID:20403613 RGD:2326175 NCBI chr 1:130,357,526...130,390,513
Ensembl chr 1:130,366,764...130,390,481 		JBrowse link
G Cd59a CD59a antigen ISO RGD PMID:10530491 RGD:1600493 NCBI chr 2:103,926,177...103,945,755
Ensembl chr 2:103,926,146...103,945,699 		JBrowse link
G Cd59b CD59b antigen ISO RGD PMID:10530491 RGD:1600493 NCBI chr 2:103,900,127...103,920,619
Ensembl chr 2:103,900,194...103,921,532 		JBrowse link
G Cdc42 cell division cycle 42 ISO protein:increased activation:hippocampus CA1 RGD PMID:17161586 RGD:2298583 NCBI chr 4:137,047,007...137,085,070
Ensembl chr 4:137,047,007...137,085,031 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A (P21) ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16968891 PMID:10451498 RGD:10043817 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B ISO protein:increased expression:skeletal muscle RGD PMID:15799773 RGD:2293627 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476 		JBrowse link
G Cfh complement component factor h ISO protein:increased expression:plasma: RGD PMID:17263982 RGD:7364988 NCBI chr 1:140,013,593...140,111,149
Ensembl chr 1:140,012,446...140,111,502 		JBrowse link
G Chat choline acetyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23075401 NCBI chr14:32,130,160...32,187,866
Ensembl chr14:32,130,160...32,187,946 		JBrowse link
G Cldn4 claudin 4 ISO protein:increased expression, altered localization:small intestine epithelium RGD PMID:17375208 RGD:2317600 NCBI chr 5:134,973,977...134,975,788
Ensembl chr 5:134,973,973...134,975,788 		JBrowse link
G Cnr1 cannabinoid receptor 1 (brain) ISO RGD PMID:19372445 RGD:2314674 NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831 		JBrowse link
G Cspg4 chondroitin sulfate proteoglycan 4 ISO RGD PMID:17565360 RGD:5686869 NCBI chr 9:56,772,388...56,807,154
Ensembl chr 9:56,772,317...56,807,154 		JBrowse link
G Ctsb cathepsin B ISO protein:increased expression:cerebral cortex, mitochondrion (rat) RGD PMID:18938146 RGD:2315506 NCBI chr14:63,359,911...63,383,372
Ensembl chr14:63,359,911...63,383,372 		JBrowse link
G Ctsg cathepsin G IMP RGD PMID:17322378 RGD:7242055 NCBI chr14:56,337,342...56,340,031
Ensembl chr14:56,337,338...56,340,031 		JBrowse link
G Cx3cl1 chemokine (C-X3-C motif) ligand 1 ISO mRNA, protein:increased expression:brain RGD PMID:19563789 RGD:4891956 NCBI chr 8:95,498,808...95,509,055
Ensembl chr 8:95,498,637...95,509,055 		JBrowse link
G Cxcl1 chemokine (C-X-C motif) ligand 1 IEP
ISO		 mRNA:increased expression:liver
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16526316 PMID:20160675 PMID:10655268 RGD:5134970, RGD:5135270 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974 		JBrowse link
G Cxcl10 chemokine (C-X-C motif) ligand 10 ISO
IEP		 mRNA:increased expression:liver
protein:increased expression:respiratory system fluid/secretion
associated with Anemia, Sickle Cell;protein:increased expression:lung		 RGD PMID:18589091 PMID:16709871 PMID:19433855 RGD:2311376, RGD:5135441, RGD:5135307 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748 		JBrowse link
G Cxcl12 chemokine (C-X-C motif) ligand 12 ISO protein:increased expression:retina RGD PMID:18709383 RGD:2306570 NCBI chr 6:117,145,496...117,158,329
Ensembl chr 6:117,145,496...117,158,328 		JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12865660 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926 		JBrowse link
G Cxcl2 chemokine (C-X-C motif) ligand 2 ISO
IEP		 mRNA:increased expression:jejunum, lung
CTD Direct Evidence: marker/mechanism
protein:increased expression:liver
mRNA:increased expression:liver		 CTD
RGD		 PMID:12468449 PMID:19691980 PMID:10655268 PMID:11580116 PMID:20160675 RGD:5134974, RGD:5135270, RGD:5135251, RGD:5134970 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797 		JBrowse link
G Cxcl3 chemokine (C-X-C motif) ligand 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459 		JBrowse link
G Cxcl5 chemokine (C-X-C motif) ligand 5 ISO protein:increased expression:liver RGD PMID:11580116 PMID:10655268 RGD:5135251, RGD:5135270 NCBI chr 5:90,907,157...90,909,484
Ensembl chr 5:90,907,219...90,909,483 		JBrowse link
G Cxcl9 chemokine (C-X-C motif) ligand 9 IEP associated with Anemia, Sickle Cell;protein:increased expression:lung RGD PMID:19433855 RGD:5135307 NCBI chr 5:92,469,190...92,475,938
Ensembl chr 5:92,469,206...92,475,938 		JBrowse link
G Cxcr3 chemokine (C-X-C motif) receptor 3 ISO mRNA:increased expression:liver RGD PMID:18589091 RGD:2311376 NCBI chr  X:100,775,141...100,777,753
Ensembl chr  X:100,775,141...100,777,875 		JBrowse link
G Cyba cytochrome b-245, alpha polypeptide ISO RGD PMID:15148062 RGD:1599683 NCBI chr 8:123,151,510...123,159,679
Ensembl chr 8:123,151,515...123,159,669 		JBrowse link
G Cybb cytochrome b-245, beta polypeptide ISO Protein:increase expression:brain
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:19193722 PMID:16766636 RGD:1599677 NCBI chr  X:9,301,493...9,354,005
Ensembl chr  X:9,301,491...9,354,010 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 ISO protein:increased expression:hippocampus (rat) RGD PMID:21114983 RGD:4890041 NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO protein:decreased expression:liver RGD PMID:21094789 RGD:4892235 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900 		JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22749977 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881 		JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 ISO protein:increased expression:kidney RGD PMID:18790177 RGD:4781446 NCBI chr  X:105,617,952...105,647,329
Ensembl chr  X:105,617,952...105,647,285 		JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 ISO protein:increased expression:brain RGD PMID:21664436 RGD:5144004 NCBI chr14:73,263,043...73,286,554
Ensembl chr14:73,263,043...73,286,554 		JBrowse link
G Dcc deleted in colorectal carcinoma ISO protein:increased expression:brain RGD PMID:17574219 RGD:2314372 NCBI chr18:71,386,703...72,484,299
Ensembl chr18:71,386,705...72,484,140 		JBrowse link
G Dsg1a desmoglein 1 alpha ISO protein:decreased expression:lung RGD PMID:19500802 RGD:2316254 NCBI chr18:20,443,930...20,476,410
Ensembl chr18:20,443,868...20,476,407 		JBrowse link
G Dsg1b desmoglein 1 beta ISO protein:decreased expression:lung RGD PMID:19500802 RGD:2316254 NCBI chr18:20,509,786...20,545,240
Ensembl chr18:20,509,786...20,543,253 		JBrowse link
G Edn1 endothelin 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17470888 PMID:18722366 RGD:4892577 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466 		JBrowse link
G Edn2 endothelin 2 ISO RGD PMID:1479622 RGD:1580920 NCBI chr 4:120,018,403...120,024,557
Ensembl chr 4:120,018,403...120,024,557 		JBrowse link
G Ednrb endothelin receptor type B ISO RGD PMID:18722366 RGD:4892577 NCBI chr14:104,052,051...104,083,248
Ensembl chr14:104,052,061...104,081,838 		JBrowse link
G Eef2 eukaryotic translation elongation factor 2 ISO protein:hypophosphorylation:cortex, hippocampus: RGD PMID:15211596 RGD:10401223 NCBI chr10:81,012,465...81,018,343
Ensembl chr10:81,012,465...81,018,332 		JBrowse link
G Efna5 ephrin A5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr17:62,909,949...63,188,431
Ensembl chr17:62,911,179...63,188,312 		JBrowse link
G Efnb2 ephrin B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 8:8,667,235...8,711,242
Ensembl chr 8:8,667,434...8,711,242 		JBrowse link
G Egf epidermal growth factor resistance ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16526316 PMID:16417467 RGD:6906916 NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965 		JBrowse link
G Egr1 early growth response 1 IEP
ISO
IMP		 Lung Reperfusion Injury; protein:increased expression:lung, nucleus (mouse)
CTD Direct Evidence: marker/mechanism
Lung Reperfusion Injury; protein:increased expression:lung, nucleus (rat)		 CTD
RGD		 PMID:12468449 PMID:19342415 PMID:16488723 PMID:16551742 RGD:5131887, RGD:5131904, RGD:5131903 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037 		JBrowse link
G Eif2a eukaryotic translation initiation factor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19041636 NCBI chr 3:58,433,252...58,464,922
Ensembl chr 3:58,433,242...58,464,922 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO protein:increased phosphorylation:kidney RGD PMID:15936177 RGD:1581062 NCBI chr 6:70,821,468...70,882,225
Ensembl chr 6:70,821,499...70,882,229 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha ISO protein:increased phosphorylation:kidney RGD PMID:15936177 RGD:1581062 NCBI chr12:78,908,846...78,933,784
Ensembl chr12:78,908,593...78,933,784 		JBrowse link
G Eno2 enolase 2, gamma neuronal ISO RGD PMID:17683050 RGD:2293745 NCBI chr 6:124,737,018...124,746,489
Ensembl chr 6:124,737,016...124,746,636 		JBrowse link
G Ep300 E1A binding protein p300 treatment ISO retina
retina; protein:altered localization:Hsp70, promoter (rat)		 RGD PMID:22143029 PMID:22143029 RGD:5686888, RGD:5686888 NCBI chr15:81,470,329...81,536,278
Ensembl chr15:81,469,552...81,536,278 		JBrowse link
G Epha2 Eph receptor A2 ISO RGD PMID:16735461 RGD:1580976 NCBI chr 4:141,028,532...141,056,695
Ensembl chr 4:141,028,551...141,056,695 		JBrowse link
G Ephx2 epoxide hydrolase 2, cytoplasmic IMP RGD PMID:19471280 RGD:5688359 NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949 		JBrowse link
G Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 ISO RGD PMID:19440222 RGD:2313668 NCBI chr 7:19,079,016...19,090,449
Ensembl chr 7:19,078,703...19,090,449 		JBrowse link
G Ets1 E26 avian leukemia oncogene 1, 5' domain ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 9:32,547,501...32,669,116
Ensembl chr 9:32,547,517...32,669,116 		JBrowse link
G F2 coagulation factor II ISO RGD PMID:20705928 RGD:5147777 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759 		JBrowse link
G Fas Fas (TNF receptor superfamily member 6) treatment ISO RGD PMID:29568770 RGD:13792595 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Fgf1 fibroblast growth factor 1 ISO Rat model using human FGF1 RGD PMID:19497570 PMID:16635575 RGD:5509879, RGD:5509881 NCBI chr18:38,971,725...39,062,532
Ensembl chr18:38,971,726...39,062,525 		JBrowse link
G Fgf2 fibroblast growth factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257 		JBrowse link
G Fgf7 fibroblast growth factor 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 2:125,876,578...125,933,105
Ensembl chr 2:125,876,578...125,933,105 		JBrowse link
G Fos FBJ osteosarcoma oncogene ISO protein:increased expression:brain
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:7922267 PMID:15121240 RGD:2293779 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047 		JBrowse link
G Fosl1 fos-like antigen 1 ISO mRNA:increased expression:hippocampus RGD PMID:15306117 RGD:1642465 NCBI chr19:5,497,726...5,505,966
Ensembl chr19:5,497,575...5,505,974 		JBrowse link
G Fosl2 fos-like antigen 2 ISO protein:increased expression:brain RGD PMID:15121240 RGD:2293779 NCBI chr 5:32,292,599...32,315,184
Ensembl chr 5:32,293,145...32,315,186 		JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked ISO RGD PMID:17250641 RGD:2307361 NCBI chr  X:73,453,089...73,472,486
Ensembl chr  X:73,453,089...73,472,800 		JBrowse link
G Gast gastrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:10594344 NCBI chr11:100,225,233...100,227,823
Ensembl chr11:100,225,233...100,227,822 		JBrowse link
G Gh growth hormone treatment ISO RGD PMID:21439711 RGD:10003153 NCBI chr11:106,191,087...106,194,529
Ensembl chr11:106,191,097...106,192,691 		JBrowse link
G Ghrl ghrelin ISO CTD Direct Evidence: therapeutic CTD PMID:16581065 NCBI chr 6:113,693,080...113,696,872
Ensembl chr 6:113,693,080...113,696,841 		JBrowse link
G Gjb1 gap junction protein, beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25530438 NCBI chr  X:100,419,982...100,429,235
Ensembl chr  X:100,419,984...100,429,235 		JBrowse link
G Glud1 glutamate dehydrogenase 1 ISO protein:decreased activity:brain RGD PMID:7808037 RGD:6484655 NCBI chr14:34,032,684...34,066,990
Ensembl chr14:34,032,684...34,067,222 		JBrowse link
G Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 ISO RGD PMID:11367746 RGD:13513922 NCBI chr 9:107,491,324...107,512,542
Ensembl chr 9:107,491,324...107,512,566 		JBrowse link
G Gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting 3 ISO RGD PMID:11367746 RGD:13513922 NCBI chr 3:108,014,591...108,053,468
Ensembl chr 3:108,014,596...108,053,462 		JBrowse link
G Gpt glutamic pyruvic transaminase, soluble ISO CTD Direct Evidence: marker/mechanism CTD PMID:8215636 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886 		JBrowse link
G Gpx1 glutathione peroxidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23743330 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542 		JBrowse link
G Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1) ISO mRNA:decreased expression:hippocampus (rat) RGD PMID:20408958 RGD:4107069 NCBI chr11:56,902,342...57,221,070
Ensembl chr11:56,902,213...57,221,070 		JBrowse link
G Grik2 glutamate receptor, ionotropic, kainate 2 (beta 2) ISO RGD PMID:17639597 RGD:2316528 NCBI chr10:48,969,776...49,666,523
Ensembl chr10:48,970,929...49,664,862 		JBrowse link
G Grik5 glutamate receptor, ionotropic, kainate 5 (gamma 2) ISO RGD PMID:17639597 RGD:2316528 NCBI chr 7:24,709,274...24,775,421
Ensembl chr 7:24,709,274...24,771,771 		JBrowse link
G Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) ISO mRNA, protein:decreased expression:cerebral cortex, hippocampus (rat) RGD PMID:20350575 RGD:2325867 NCBI chr16:9,385,765...9,813,744
Ensembl chr16:9,385,762...9,813,424 		JBrowse link
G Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) ISO mRNA, protein:decreased expression:cerebral cortex, hippocampus (rat) RGD PMID:20350575 RGD:2325867 NCBI chr 6:135,690,219...136,150,658
Ensembl chr 6:135,690,231...136,150,509 		JBrowse link
G Gsr glutathione reductase treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:24904723 RGD:10401882 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191 		JBrowse link
G Gstp1 glutathione S-transferase, pi 1 IEP RGD PMID:17142801 RGD:6903953 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:7635938 NCBI chr18:36,637,980...36,648,858
Ensembl chr18:36,637,980...36,648,858 		JBrowse link
G Hc hemolytic complement ISO RGD PMID:15158333 RGD:1600597 NCBI chr 2:34,873,341...34,958,518
Ensembl chr 2:34,873,343...34,951,450 		JBrowse link
G Hgf hepatocyte growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 5:16,758,493...16,827,448
Ensembl chr 5:16,758,493...16,825,150 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit treatment ISO Spinal Cord Reperfusion Injury
Limb Reperfusion Injury		 RGD PMID:16465055 PMID:23816242 RGD:9068924, RGD:9068927 NCBI chr12:73,948,098...73,994,328
Ensembl chr12:73,948,149...73,994,304 		JBrowse link
G Hmgb1 high mobility group box 1 treatment ISO RGD PMID:22392147 RGD:10402071 NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase ISO
IMP		 associated with Diabetes Mellitus, Experimental RGD PMID:21724106 PMID:16009498 PMID:18398369 RGD:5508445, RGD:5508473, RGD:2315888 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444 		JBrowse link
G Hmox1 heme oxygenase 1 ISO CTD Direct Evidence: marker/mechanism|therapeutic
protein:increased expression:serum, Bronchoalveolar Lavage Fluid 		CTD
RGD		 PMID:12352873 PMID:16982915 PMID:17660127 PMID:17906103 PMID:23075401 More... RGD:1582708, RGD:4145514, RGD:4145338 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hrh3 histamine receptor H3 ISO RGD PMID:17169356 RGD:1626416 NCBI chr 2:179,741,258...179,746,264
Ensembl chr 2:179,741,258...179,746,281 		JBrowse link
G Hspa1a heat shock protein 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:7922267 NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132 		JBrowse link
G Hspa1b heat shock protein 1B ISO RGD PMID:10965299 PMID:10550516 RGD:7242748, RGD:7242749 NCBI chr17:35,175,405...35,178,214
Ensembl chr17:35,175,412...35,178,214 		JBrowse link
G Hspa5 heat shock protein 5 ISO associated with Diabetes Mellitus, experimental (D003921): protein:increased expression:brain RGD PMID:22075494 RGD:5685650 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559 		JBrowse link
G Hspa8 heat shock protein 8 ISO CTD Direct Evidence: therapeutic CTD PMID:10216529 NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383 		JBrowse link
G Hspb1 heat shock protein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:19193722 NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417 		JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11557319 PMID:23743330 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113 		JBrowse link
G Id3 inhibitor of DNA binding 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 4:135,871,133...135,872,703
Ensembl chr 4:135,870,808...135,873,066 		JBrowse link
G Ifng interferon gamma ISO protein:increased expression:plasma RGD PMID:19514843 RGD:2308950 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Igf1 insulin-like growth factor 1 IEP RGD PMID:16306169 RGD:1598442 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904 		JBrowse link
G Il10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:18460982 PMID:19514843 PMID:12388354 PMID:16141682 RGD:2308950, RGD:5508171, RGD:1598625 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il12a interleukin 12a ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 3:68,597,977...68,605,881
Ensembl chr 3:68,597,977...68,605,880 		JBrowse link
G Il13 interleukin 13 ISO protein:decreased expression:plasma RGD PMID:18354382 PMID:18354382 RGD:2301685, RGD:2301685 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529 		JBrowse link
G Il18 interleukin 18 IMP
IEP		 protein:increased expression:serum RGD PMID:19394645 PMID:16052682 RGD:4889555, RGD:4889825 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140 		JBrowse link
G Il1a interleukin 1 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:23875703 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892 		JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:10594344 PMID:12468449 PMID:15829914 PMID:19058328 PMID:19673871 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il6 interleukin 6 ISO
IEP		 CTD Direct Evidence: marker/mechanism
protein:increased expression:lung		 CTD
RGD		 PMID:15829914 PMID:17032661 PMID:18258783 PMID:19673871 PMID:21940958 More... RGD:4143250, RGD:4143253 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Il6ra interleukin 6 receptor, alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:21940958 NCBI chr 3:89,776,631...89,820,503
Ensembl chr 3:89,771,366...89,820,503 		JBrowse link
G Il6st interleukin 6 signal transducer ISO CTD Direct Evidence: marker/mechanism CTD PMID:21940958 NCBI chr13:112,600,604...112,643,394
Ensembl chr13:112,600,604...112,646,620 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D ISO CTD Direct Evidence: therapeutic CTD PMID:25780291 NCBI chr 1:87,548,034...87,648,232
Ensembl chr 1:87,548,034...87,648,229 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 ISO CTD Direct Evidence: therapeutic CTD PMID:25780291 NCBI chr10:119,977,553...120,038,035
Ensembl chr10:119,977,553...120,038,035 		JBrowse link
G Irf1 interferon regulatory factor 1 ISO mRNA:increased expression:cerebral cortex RGD PMID:12437578 RGD:632385 NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200 		JBrowse link
G Itga2b integrin alpha 2b ISO RGD PMID:11705748 RGD:2316361 NCBI chr11:102,344,123...102,360,709
Ensembl chr11:102,344,123...102,360,948 		JBrowse link
G Itga5 integrin alpha 5 (fibronectin receptor alpha) ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr15:103,252,713...103,275,218
Ensembl chr15:103,252,713...103,275,190 		JBrowse link
G Itgb3 integrin beta 3 ISO RGD PMID:11705748 RGD:2316361 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302 		JBrowse link
G Jak2 Janus kinase 2 IMP RGD PMID:20440769 RGD:6483026 NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480 		JBrowse link
G Jun jun proto-oncogene ISO CTD Direct Evidence: marker/mechanism CTD PMID:7922267 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459 		JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 ISO RGD PMID:10708603 RGD:1581697 NCBI chr 6:142,510,563...142,517,340
Ensembl chr 6:142,510,563...142,517,340 		JBrowse link
G Kdr kinase insert domain protein receptor ISO mRNA:increased expression:hippocampus
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16526316 PMID:17402857 RGD:5684415 NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118 		JBrowse link
G Keap1 kelch-like ECH-associated protein 1 IEP
ISO		 protein:decreased expression:brain, neuron, cytoplasm (mouse)
protein:decreased expression:left coronary artery (rat)		 RGD PMID:21075092 PMID:18078953 RGD:6893270, RGD:6902919 NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657 		JBrowse link
G Klk1 kallikrein 1 ISO RGD PMID:12746231 RGD:1641806 NCBI chr 7:43,874,784...43,879,046
Ensembl chr 7:43,874,784...43,879,042 		JBrowse link
G Ldlr low density lipoprotein receptor ISO RGD PMID:17288738 RGD:2324630 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215 		JBrowse link
G Lep leptin ISO RGD PMID:21086559 RGD:5128549 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876 		JBrowse link
G Lig3 ligase III, DNA, ATP-dependent ISO protein:increased expression:brain RGD PMID:17412650 RGD:2302580 NCBI chr11:82,671,977...82,695,100
Ensembl chr11:82,671,934...82,695,100 		JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor ISO protein:increased expression:brain RGD PMID:19773801 RGD:2325809 NCBI chr 9:106,765,952...106,769,137
Ensembl chr 9:106,715,511...106,769,178 		JBrowse link
G Map2 microtubule-associated protein 2 ISO protein:increased expression:serum RGD PMID:21948028 RGD:6483082 NCBI chr 1:66,214,337...66,481,742
Ensembl chr 1:66,214,432...66,481,742 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20302854 PMID:16699462 RGD:1582310 NCBI chr14:33,099,855...33,169,215
Ensembl chr14:33,099,855...33,169,115 		JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 ISO protein:increased activity:hippocampus RGD PMID:16805806 RGD:2293339 NCBI chr17:25,116,480...25,155,951
Ensembl chr17:25,111,127...25,155,951 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19667931 PMID:20302854 NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248 		JBrowse link
G Mb myoglobin ISO RGD PMID:12788661 RGD:1582427 NCBI chr15:76,899,687...76,934,868
Ensembl chr15:76,899,687...76,934,870 		JBrowse link
G Mbl1 mannose-binding lectin (protein A) 1 IMP
IEP		 protein:decreased expression:serum RGD PMID:16982912 PMID:15509537 RGD:1582132, RGD:6903263 NCBI chr14:40,873,413...40,885,861
Ensembl chr14:40,873,415...40,881,558 		JBrowse link
G Mbl2 mannose-binding lectin (protein C) 2 ISO
IEP		 protein:increased expression:serum RGD PMID:15882434 PMID:15509537 RGD:6903262, RGD:6903263 NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087 		JBrowse link
G Mc1r melanocortin 1 receptor no_association IEP RGD PMID:18757499 RGD:5687323 NCBI chr 8:124,133,839...124,137,483
Ensembl chr 8:124,133,846...124,137,483 		JBrowse link
G Mdk midkine IDA RGD PMID:15780085 RGD:1582475 NCBI chr 2:91,760,149...91,762,348
Ensembl chr 2:91,760,150...91,762,642 		JBrowse link
G Met met proto-oncogene ISO mRNA:increased expression:retina (rat) RGD PMID:17113948 RGD:2317505 NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979 		JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) disease_progression IMP RGD PMID:18055556 RGD:4891010 NCBI chr10:75,695,187...75,696,111
Ensembl chr10:75,695,187...75,696,074 		JBrowse link
G Mir148b microRNA 148b ISO CTD Direct Evidence: marker/mechanism CTD PMID:30308185 NCBI chr15:103,193,552...103,193,648
Ensembl chr15:103,193,552...103,193,648 		JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO protein:increased protein, activity:brain RGD PMID:15099024 RGD:2325962 NCBI chr 9:7,445,822...7,455,975
Ensembl chr 9:7,445,822...7,455,975 		JBrowse link
G Mmp9 matrix metallopeptidase 9 IEP
ISO
IDA		 protein:increased expression:limb muscle (mouse)
CTD Direct Evidence: marker/mechanism
associated with lung injury; mRNA, protein:increased expression:lung		 CTD
RGD		 PMID:23075401 PMID:16251419 PMID:19545667 PMID:16551680 RGD:1582631, RGD:5129531, RGD:1582618 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770 		JBrowse link
G Mpo myeloperoxidase ISO protein:increased activity:lung
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:8869312 PMID:10706834 PMID:12024109 PMID:16971220 PMID:19058328 More... RGD:5130958 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239 		JBrowse link
G mt-Atp6 ATP synthase 6, mitochondrial ISO RGD PMID:20450733 RGD:5490294 NCBI chr MT:7,927...8,607
Ensembl chr MT:7,927...8,607 		JBrowse link
G mt-Atp8 ATP synthase 8, mitochondrial ISO RGD PMID:20450733 RGD:5490294 NCBI chr MT:7,766...7,969
Ensembl chr MT:7,766...7,969 		JBrowse link
G mt-Cytb cytochrome b, mitochondrial ISO mRNA:decreased expression:kidney RGD PMID:7692737 RGD:2298967 NCBI chr MT:14,145...15,288
Ensembl chr MT:14,145...15,288 		JBrowse link
G Mt2 metallothionein 2 IEP mRNA:increased expression:cerebrum (mouse) RGD PMID:12122050 RGD:6483850 NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196 		JBrowse link
G Mt3 metallothionein 3 IMP RGD PMID:19635467 RGD:6480529 NCBI chr 8:94,879,235...94,880,776
Ensembl chr 8:94,879,235...94,880,774 		JBrowse link
G Muc1 mucin 1, transmembrane ISO RGD PMID:23977093 RGD:7349380 NCBI chr 3:89,136,363...89,140,688
Ensembl chr 3:89,136,364...89,140,688 		JBrowse link
G Myd88 myeloid differentiation primary response gene 88 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25780291 NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477 		JBrowse link
G Nes nestin ISO protein:increased expression:cerebral cortex RGD PMID:17569338 RGD:1642074 NCBI chr 3:87,878,400...87,887,758
Ensembl chr 3:87,878,385...87,887,758 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO protein:increased expression:small intestine RGD PMID:20107953 RGD:5131440 NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102 		JBrowse link
G Nos1 nitric oxide synthase 1, neuronal ISO RGD PMID:17451676 RGD:1642142 NCBI chr 5:118,004,904...118,096,905
Ensembl chr 5:117,919,097...118,096,905 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible ISO
IEP		 mRNA:increased expression:liver
CTD Direct Evidence: marker/mechanism
protein:increased expression:venule, arteriole, endothelium (mouse)
mRNA, protein:increased expression:liver		 CTD
RGD		 PMID:10383581 PMID:19673871 PMID:23061969 PMID:23075401 PMID:11592783 More... RGD:2325259, RGD:5509100, RGD:1580938 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell ISO CTD Direct Evidence: marker/mechanism CTD PMID:21968084 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472 		JBrowse link
G Nox4 NADPH oxidase 4 ISO mRNA:increased expression:cerebral cortex RGD PMID:18438942 RGD:2324666 NCBI chr 7:86,893,638...87,047,918
Ensembl chr 7:86,895,304...87,047,918 		JBrowse link
G Oga O-GlcNAcase ISO RGD PMID:16899550 RGD:2305957 NCBI chr19:45,738,698...45,772,274
Ensembl chr19:45,738,698...45,772,276 		JBrowse link
G Oprm1 opioid receptor, mu 1 ISO mRNA, protein:decreased expression:hippocampus RGD PMID:17360495 RGD:2316611 NCBI chr10:6,708,593...6,988,209
Ensembl chr10:6,708,506...6,988,198 		JBrowse link
G Otc ornithine transcarbamylase ISO protein:increased activity:serum RGD PMID:1499453 RGD:4144083 NCBI chr  X:10,118,584...10,187,275
Ensembl chr  X:10,118,544...10,187,263 		JBrowse link
G Oxt oxytocin ISO RGD PMID:18403049 RGD:2304111 NCBI chr 2:130,416,432...130,418,974
Ensembl chr 2:130,418,093...130,418,974 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 IMP
ISO		 CTD Direct Evidence: marker/mechanism
protein:increased expression:liver (rat)		 CTD
RGD		 PMID:15696051 PMID:16798486 PMID:9390645 PMID:21850691 RGD:5510018, RGD:5510020 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819 		JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 ISO
IMP		 RGD PMID:19142196 PMID:19142196 RGD:6483555, RGD:6483555 NCBI chr 2:143,388,053...143,658,204
Ensembl chr 2:143,388,076...143,658,205 		JBrowse link
G Pde5a phosphodiesterase 5A, cGMP-specific ISO RGD PMID:19474186 RGD:2314462 NCBI chr 3:122,522,822...122,653,023
Ensembl chr 3:122,522,596...122,653,023 		JBrowse link
G Pecam1 platelet/endothelial cell adhesion molecule 1 ISO
IEP		 protein:decreased expression:lung (rat)
protein:increased expression:brain (mouse)		 RGD PMID:12121711 PMID:21872880 PMID:22382321 RGD:2311660, RGD:6771206, RGD:6766379 NCBI chr11:106,545,039...106,606,107
Ensembl chr11:106,545,043...106,641,454 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO proetin:decreased dimerization:skeletal muscle (rat) RGD PMID:19100383 RGD:4108481 NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725 		JBrowse link
G Pink1 PTEN induced putative kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35312153 NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618 		JBrowse link
G Pklr pyruvate kinase liver and red blood cell ISO RGD PMID:17013507 RGD:1625588 NCBI chr 3:89,043,429...89,054,122
Ensembl chr 3:89,043,449...89,054,091 		JBrowse link
G Pla2g2a phospholipase A2, group IIA (platelets, synovial fluid) ISO CTD Direct Evidence: marker/mechanism CTD PMID:12967936 NCBI chr 4:138,559,168...138,562,500
Ensembl chr 4:138,559,171...138,562,497 		JBrowse link
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) ISO protein:increased activity:alveolar macrophage RGD PMID:1642455 RGD:1642456 NCBI chr 1:149,705,369...149,837,041
Ensembl chr 1:149,705,369...149,837,041 		JBrowse link
G Plat plasminogen activator, tissue ISO CTD Direct Evidence: therapeutic CTD
RGD		 PMID:9472885 PMID:15223382 RGD:2311674 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860 		JBrowse link
G Plau plasminogen activator, urokinase ISO
IDA		 protein:increased expression:spinal cord (rat)
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:15181847 PMID:19663807 PMID:18586014 RGD:6483808, RGD:6483830 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453 		JBrowse link
G Plaur plasminogen activator, urokinase receptor IMP RGD PMID:18606671 RGD:6483829 NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393 		JBrowse link
G Pld2 phospholipase D2 ISO protein:increased expression:hippocampus CA1, hippocampus granule cell layer
mRNA:decreased expression:brainstem, cerebellum		 RGD PMID:17393174 PMID:17024567 RGD:2299901, RGD:2299902 NCBI chr11:70,430,318...70,448,936
Ensembl chr11:70,430,890...70,448,936 		JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase ISO protein:increased expression:medulla oblongata (human) RGD PMID:21061149 RGD:5128821 NCBI chr11:98,277,449...98,279,006
Ensembl chr11:98,277,276...98,279,007 		JBrowse link
G Polb polymerase (DNA directed), beta ISO protein:increased expression:cerebral cortex RGD PMID:17412650 RGD:2302580 NCBI chr 8:23,118,135...23,143,482
Ensembl chr 8:23,118,142...23,143,451 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO liver ischemia/reperfusion injury (rat)
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:19151258 PMID:21305343 RGD:5509942 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO CTD Direct Evidence: therapeutic CTD PMID:12468449 PMID:24011919 PMID:24433871 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360 		JBrowse link
G Ppp3ca protein phosphatase 3, catalytic subunit, alpha isoform ISO RGD PMID:14762344 RGD:1580702 NCBI chr 3:136,375,778...136,643,488
Ensembl chr 3:136,375,885...136,643,488 		JBrowse link
G Ppp3cb protein phosphatase 3, catalytic subunit, beta isoform IAGP RGD PMID:14615291 RGD:1580705 NCBI chr14:20,549,432...20,596,641
Ensembl chr14:20,549,432...20,596,641 		JBrowse link
G Prdx6 peroxiredoxin 6 IAGP RGD PMID:16766642 RGD:1580710 NCBI chr 1:161,067,682...161,078,780
Ensembl chr 1:161,067,682...161,078,789 		JBrowse link
G Prkca protein kinase C, alpha ISO RGD PMID:17905752 RGD:2292474 NCBI chr11:107,824,213...108,237,360
Ensembl chr11:107,824,213...108,234,754 		JBrowse link
G Prss1 protease, serine 1 (trypsin 1) ISO RGD PMID:11062314 RGD:1599961 NCBI chr 6:41,435,864...41,440,720
Ensembl chr 6:41,435,866...41,440,720 		JBrowse link
G Ptafr platelet-activating factor receptor treatment IAGP
ISO		 RGD PMID:12812996 PMID:11139461 RGD:1581279, RGD:10043168 NCBI chr 4:132,291,378...132,309,994
Ensembl chr 4:132,291,378...132,309,994 		JBrowse link
G Pten phosphatase and tensin homolog ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19038262 PMID:17239858 RGD:2292538 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
G Ptges prostaglandin E synthase IEP
ISO		 RGD PMID:16864802 PMID:12431630 RGD:2300094, RGD:2300116 NCBI chr 2:30,779,483...30,793,309
Ensembl chr 2:30,779,483...30,819,875 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:10594344 PMID:16385084 RGD:5688223 NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO protein:decreased expression:kidney
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:10588920 PMID:10594344 PMID:11567657 PMID:16386242 PMID:18258783 More... RGD:5135045, RGD:5508180, RGD:1580660 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Ptk2 PTK2 protein tyrosine kinase 2 ISO protein:increased tyrosine phosphorylation:kidney RGD PMID:17620366 RGD:2292577 NCBI chr15:73,076,951...73,297,192
Ensembl chr15:73,076,951...73,295,129 		JBrowse link
G Ptk2b PTK2 protein tyrosine kinase 2 beta ISO protein:increased phosphorylation:hippocampus RGD PMID:15970382 RGD:1642621 NCBI chr14:66,390,706...66,518,549
Ensembl chr14:66,390,706...66,518,501 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) ISO protein:increased expression:nucleus, liver
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:20302854 PMID:23743330 PMID:18621400 RGD:2298777 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G S100b S100 protein, beta polypeptide, neural ISO RGD PMID:18840784 RGD:5508834 NCBI chr10:76,089,670...76,097,153
Ensembl chr10:76,089,687...76,096,993 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 IDA RGD PMID:16403835 RGD:1580913 NCBI chr 3:115,504,082...115,508,704
Ensembl chr 3:115,504,082...115,508,721 		JBrowse link
G Scfd1 Sec1 family domain containing 1 ISO protein:increased expression:cerebral cortex RGD PMID:9195952 RGD:633771 NCBI chr12:51,424,296...51,496,887
Ensembl chr12:51,424,293...51,496,884 		JBrowse link
G Sele selectin, endothelial cell ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17112405 PMID:23743330 PMID:19489247 RGD:2313598 NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,773...163,885,246 		JBrowse link
G Sell selectin, lymphocyte ISO RGD PMID:19489247 RGD:2313598 NCBI chr 1:163,889,556...163,908,354
Ensembl chr 1:163,889,551...163,911,750 		JBrowse link
G Selp selectin, platelet ISO
IEP		 RGD PMID:18521901 PMID:21701413 RGD:2312314, RGD:6218990 NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595 		JBrowse link
G Serpine2 serine (or cysteine) peptidase inhibitor, clade E, member 2 ISO RGD PMID:8261109 RGD:2317936 NCBI chr 1:79,772,038...79,836,382
Ensembl chr 1:79,771,914...79,838,897 		JBrowse link
G Serping1 serine (or cysteine) peptidase inhibitor, clade G, member 1 treatment ISO RGD PMID:23991040 RGD:8661644 NCBI chr 2:84,595,704...84,605,778
Ensembl chr 2:84,595,731...84,605,788 		JBrowse link
G Sftpc surfactant associated protein C ISO mRNA:decreased expression:lung RGD PMID:20560845 RGD:4144062 NCBI chr14:70,758,381...70,761,521
Ensembl chr14:70,758,389...70,761,521 		JBrowse link
G Sirt7 sirtuin 7 ISO CTD Direct Evidence: therapeutic CTD PMID:28675767 NCBI chr11:120,509,197...120,515,840
Ensembl chr11:120,509,198...120,516,066 		JBrowse link
G Sis sucrase isomaltase (alpha-glucosidase) ISO RGD PMID:9724271 RGD:1625550 NCBI chr 3:72,795,890...72,875,196
Ensembl chr 3:72,795,890...72,875,196 		JBrowse link
G Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 ISO mRNA, protein:increased expression:brain RGD PMID:19781384 RGD:2313601 NCBI chr 4:118,965,942...118,994,527
Ensembl chr 4:118,965,908...118,995,180 		JBrowse link
G Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 ISO mRNA, protein:increased expression:brain RGD PMID:19781384 RGD:2313601 NCBI chr 6:122,704,783...122,779,149
Ensembl chr 6:122,704,768...122,778,599 		JBrowse link
G Slc30a4 solute carrier family 30 (zinc transporter), member 4 ISO mRNA:increased expression:brain RGD PMID:18289514 RGD:2299950 NCBI chr 2:122,523,153...122,544,583
Ensembl chr 2:122,523,153...122,544,583 		JBrowse link
G Slc34a1 solute carrier family 34 (sodium phosphate), member 1 ISO protein:decreased expression:renal proximal tubule RGD PMID:15775707 RGD:2311304 NCBI chr13:55,547,435...55,562,508
Ensembl chr13:55,546,000...55,563,405 		JBrowse link
G Slc6a11 solute carrier family 6 (neurotransmitter transporter, GABA), member 11 ISO RGD PMID:13678673 RGD:1299345 NCBI chr 6:114,108,202...114,226,847
Ensembl chr 6:114,108,202...114,226,913 		JBrowse link
G Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1 ISO RGD PMID:18037393 RGD:2316975 NCBI chr17:81,680,534...82,045,816
Ensembl chr17:81,680,534...82,045,806 		JBrowse link
G Slc8a2 solute carrier family 8 (sodium/calcium exchanger), member 2 ISO RGD PMID:18037393 RGD:2316975 NCBI chr 7:15,861,540...15,894,988
Ensembl chr 7:15,863,751...15,894,988 		JBrowse link
G Slc8a3 solute carrier family 8 (sodium/calcium exchanger), member 3 ISO RGD PMID:18037393 RGD:2316975 NCBI chr12:81,244,689...81,380,506
Ensembl chr12:81,244,689...81,379,954 		JBrowse link
G Slc9a1 solute carrier family 9 (sodium/hydrogen exchanger), member 1 ISO CTD Direct Evidence: therapeutic CTD
RGD		 PMID:19027022 PMID:20337040 RGD:6771332 NCBI chr 4:133,097,022...133,151,013
Ensembl chr 4:133,097,017...133,151,013 		JBrowse link
G Slco1b2 solute carrier organic anion transporter family, member 1b2 ISO mRNA:decreased expression:liver RGD PMID:16858290 RGD:2303111 NCBI chr 6:141,575,178...141,632,372
Ensembl chr 6:141,575,244...141,632,372 		JBrowse link
G Slk STE20-like kinase ISO protein:increased expression:kidney RGD PMID:12965890 RGD:2304069 NCBI chr19:47,568,458...47,633,685
Ensembl chr19:47,568,117...47,633,685 		JBrowse link
G Slpi secretory leukocyte peptidase inhibitor ISO CTD Direct Evidence: therapeutic CTD PMID:8215636 NCBI chr 2:164,195,990...164,231,086
Ensembl chr 2:164,195,990...164,231,015 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 ISO CTD Direct Evidence: therapeutic CTD PMID:25780291 NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 ISO associated with Brain Ischemia;mRNA, protein:increased expression:cerebral cortex RGD PMID:12437578 RGD:632385 NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873 		JBrowse link
G Socs4 suppressor of cytokine signaling 4 ISO mRNA:increased expression:hippocampus RGD PMID:17880360 RGD:2303397 NCBI chr14:47,514,377...47,533,559
Ensembl chr14:47,514,388...47,533,559 		JBrowse link
G Sod1 superoxide dismutase 1, soluble IDA
ISO		 CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:15364863 PMID:16397181 PMID:23061969 PMID:23743330 PMID:15364863 RGD:1580834 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217 		JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial ISO protein:increased expression:liver
CTD Direct Evidence: marker/mechanism|therapeutic		 CTD
RGD		 PMID:8215636 PMID:16682413 PMID:19193722 PMID:19917352 PMID:21940958 More... RGD:1582141, RGD:1581259 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950 		JBrowse link
G Sod3 superoxide dismutase 3, extracellular IDA RGD PMID:15778274 RGD:1581264 NCBI chr 5:52,521,146...52,527,080
Ensembl chr 5:52,521,133...52,528,760 		JBrowse link
G Spp1 secreted phosphoprotein 1 IAGP RGD PMID:20548025 RGD:6903275 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916 		JBrowse link
G Src Rous sarcoma oncogene ISO protein:increased phosphorylation:hippocampus CA1 (rat) RGD PMID:20197063 RGD:2325012 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 ISO protein:increased serine phosphorylation:brain
protein:increased phosphorylation:kidney		 RGD PMID:15262323 PMID:17670769 RGD:1600103, RGD:2291900 NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024 		JBrowse link
G Stat2 signal transducer and activator of transcription 2 ISO mRNA:increased expression:hippocampus RGD PMID:17880360 RGD:2303397 NCBI chr10:128,106,367...128,128,722
Ensembl chr10:128,106,428...128,128,718 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21940958 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A ISO mRNA:increased expression:hippocampus RGD PMID:17880360 RGD:2303397 NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B ISO mRNA:increased expression:hippocampus RGD PMID:17880360 RGD:2303397 NCBI chr11:100,671,557...100,741,407
Ensembl chr11:100,671,557...100,741,550 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 ISO mRNA:increased expression:hippocampus RGD PMID:17880360 RGD:2303397 NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826 		JBrowse link
G Stc1 stanniocalcin 1 ISO mRNA:increased expression:cerebral cortex RGD PMID:15485913 RGD:2324700 NCBI chr14:69,266,738...69,278,850
Ensembl chr14:69,266,687...69,279,253 		JBrowse link
G Stc2 stanniocalcin 2 ISO mRNA, protein:increased expression:cerebral cortex RGD PMID:15485913 RGD:2324700 NCBI chr11:31,309,441...31,320,061
Ensembl chr11:31,307,307...31,320,074 		JBrowse link
G Sult1e1 sulfotransferase family 1E, member 1 ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:25922074 PMID:16908442 RGD:2302564 NCBI chr 5:87,723,827...87,739,470
Ensembl chr 5:87,723,828...87,739,453 		JBrowse link
G Tbxas1 thromboxane A synthase 1, platelet ISO associated with Cholestasis, Extrahepatic RGD PMID:8680115 PMID:15000260 RGD:1601451 RGD:1601475 NCBI chr 6:38,817,897...39,061,524
Ensembl chr 6:38,852,338...39,061,519 		JBrowse link
G Tert telomerase reverse transcriptase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16968891 NCBI chr13:73,775,030...73,797,962
Ensembl chr13:73,775,030...73,797,962 		JBrowse link
G Tfam transcription factor A, mitochondrial ISO RGD PMID:22266265 RGD:6767573 NCBI chr10:71,061,298...71,074,157
Ensembl chr10:71,061,294...71,074,110 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor II ISO RGD PMID:15613744 RGD:1579926 NCBI chr 9:115,916,763...116,004,431
Ensembl chr 9:115,913,361...116,004,428 		JBrowse link
G Th tyrosine hydroxylase ISO protein:increased expression:medulla oblongata (human) RGD PMID:21061149 RGD:5128821 NCBI chr 7:142,446,516...142,453,732
Ensembl chr 7:142,446,489...142,484,865 		JBrowse link
G Thbd thrombomodulin IDA RGD PMID:19342415 RGD:5131887 NCBI chr 2:148,246,391...148,250,108
Ensembl chr 2:148,246,386...148,250,108 		JBrowse link
G Thbs1 thrombospondin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614 		JBrowse link
G Thy1 thymus cell antigen 1, theta ISO CTD Direct Evidence: marker/mechanism CTD PMID:23075401 NCBI chr 9:43,954,681...43,959,876
Ensembl chr 9:43,954,681...43,959,876 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25780291 NCBI chr17:56,576,462...56,583,767
Ensembl chr17:56,576,319...56,583,786 		JBrowse link
G Timp3 tissue inhibitor of metalloproteinase 3 ISO protein:decreased expression:brain RGD PMID:17551674 RGD:2290424 NCBI chr10:86,136,276...86,185,369
Ensembl chr10:86,136,236...86,185,370 		JBrowse link
G Tjp1 tight junction protein 1 ISO protein:decreased expression:brain, endothelial cell RGD PMID:19374856 PMID:19929946 RGD:2325135, RGD:2325127 NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529 		JBrowse link
G Tlr2 toll-like receptor 2 ISO mRNA, protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:25780291 PMID:15912106 RGD:2312727 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074 		JBrowse link
G Tlr3 toll-like receptor 3 ISO protein:increased expression:liver (rat) RGD PMID:21355876 RGD:5128693 NCBI chr 8:45,848,702...45,864,112
Ensembl chr 8:45,848,702...45,864,117 		JBrowse link
G Tlr4 toll-like receptor 4 ISO
IMP		 protein:increased expression:liver
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:25780291 PMID:27064547 PMID:19473433 PMID:17126102 RGD:2312503, RGD:4144169 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 ISO protein:increased expression:liver RGD PMID:18005084 RGD:2291961 NCBI chr15:99,290,828...99,307,930
Ensembl chr15:99,290,763...99,307,930 		JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:10706834 PMID:12024109 PMID:15829914 PMID:16971220 PMID:17112405 More... NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a ISO RGD PMID:17109621 RGD:1624182 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447 		JBrowse link
G Trp53 transformation related protein 53 ISO protein:increased expression:brain, mitochondrion RGD PMID:17661174 RGD:2290568 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 treatment ISO RGD PMID:20554625 RGD:4891135 NCBI chr 9:8,543,868...8,680,753
Ensembl chr 9:8,544,143...8,680,742 		JBrowse link
G Trpm7 transient receptor potential cation channel, subfamily M, member 7 ISO mRNA,protein:increased expression:hippocampus RGD PMID:18395621 RGD:5684390 NCBI chr 2:126,633,478...126,718,181
Ensembl chr 2:126,633,485...126,718,150 		JBrowse link
G Try10 trypsin 10 ISO RGD PMID:11062314 RGD:1599961 NCBI chr 6:41,331,039...41,334,878
Ensembl chr 6:41,331,039...41,334,848 		JBrowse link
G Txn1 thioredoxin 1 ISO mRNA:decreased expression:cerebral cortex RGD PMID:19128823 RGD:5685030 NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411 		JBrowse link
G Txn2 thioredoxin 2 ISO mRNA:decreased expression:cerebral cortex RGD PMID:19128823 RGD:5685030 NCBI chr15:77,799,251...77,813,194
Ensembl chr15:77,799,247...77,813,206 		JBrowse link
G Txnrd1 thioredoxin reductase 1 ISO mRNA:decreased expression:cerebral cortex
mRNA:decreased expression:spinal cord		 RGD PMID:19128823 PMID:19409971 RGD:5685030, RGD:5685028 NCBI chr10:82,669,785...82,733,558
Ensembl chr10:82,669,785...82,733,546 		JBrowse link
G Txnrd2 thioredoxin reductase 2 ISO mRNA:decreased expression:cerebral cortex RGD PMID:19128823 RGD:5685030 NCBI chr16:18,245,167...18,297,823
Ensembl chr16:18,245,134...18,297,823 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO mRNA:increased expression:kidney RGD PMID:18813897 RGD:2313108 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337 		JBrowse link
G Vegfc vascular endothelial growth factor C ISO RGD PMID:18704465 RGD:2315487 NCBI chr 8:54,530,567...54,639,489
Ensembl chr 8:54,530,641...54,640,131 		JBrowse link
G Vegfd vascular endothelial growth factor D ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr  X:163,156,282...163,185,643
Ensembl chr  X:163,156,374...163,185,646 		JBrowse link
G Vim vimentin ISO CTD Direct Evidence: marker/mechanism CTD PMID:23075401 NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637 		JBrowse link
G Vip vasoactive intestinal polypeptide IDA RGD PMID:21693218 RGD:5685379 NCBI chr10:5,589,131...5,597,617
Ensembl chr10:5,589,218...5,597,617 		JBrowse link
G Wnt3a wingless-type MMTV integration site family, member 3A ISO CTD Direct Evidence: therapeutic CTD PMID:23875703 NCBI chr11:59,138,859...59,181,579
Ensembl chr11:59,138,859...59,181,578 		JBrowse link
G Xdh xanthine dehydrogenase treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:12910483 PMID:23403765 RGD:7247700 NCBI chr17:74,190,890...74,257,369
Ensembl chr17:74,190,890...74,257,191 		JBrowse link
G Xrcc1 X-ray repair complementing defective repair in Chinese hamster cells 1 ISO protein:increased expression:brain RGD PMID:17412650 RGD:2302580 NCBI chr 7:24,246,124...24,272,863
Ensembl chr 7:24,245,714...24,272,865 		JBrowse link
G Zfp354a zinc finger protein 354A ISO mRNA:decreased expression:kidney RGD PMID:8382778 RGD:1300202 NCBI chr11:50,950,052...50,963,626
Ensembl chr11:50,950,084...50,963,626 		JBrowse link
Cardiac Allograft Vasculopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F3 coagulation factor III ISO RGD PMID:9916935 RGD:11341701 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697 		JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K ISO RGD PMID:21489814 RGD:155260371 NCBI chr13:58,538,946...58,551,157
Ensembl chr13:58,538,956...58,551,157 		JBrowse link
G Pdgfd platelet-derived growth factor, D polypeptide ISO RGD PMID:19213942 RGD:9854642 NCBI chr 9:6,168,377...6,534,284
Ensembl chr 9:6,168,584...6,378,850 		JBrowse link
Chronic Allograft Dysfunction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor treatment ISO RGD PMID:22217518 PMID:23769041 RGD:7245568, RGD:8695995 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910 		JBrowse link
G C3 complement component 3 treatment ISO RGD PMID:25122638 RGD:11040803 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G Cd40 CD40 antigen treatment ISO RGD PMID:22826618 RGD:11352297 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868 		JBrowse link
G Cd40lg CD40 ligand treatment ISO liver RGD PMID:22826618 RGD:11352297 NCBI chr  X:56,257,448...56,269,402
Ensembl chr  X:56,257,503...56,269,402 		JBrowse link
G F7 coagulation factor VII treatment ISO human protein in a rat model RGD PMID:12095034 RGD:11049508 NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809 		JBrowse link
G Hmgb1 high mobility group box 1 treatment ISO RGD PMID:22217518 RGD:7245568 NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299 		JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment ISO RGD PMID:23985719 RGD:10041002 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140 		JBrowse link
G Tnf tumor necrosis factor treatment ISO RGD PMID:24598936 RGD:10450586 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
Chronic Allograft Nephropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 ISO RGD PMID:20176611 RGD:11541086 NCBI chr 4:40,143,265...40,199,009
Ensembl chr 4:40,143,081...40,198,338 		JBrowse link
G Alb albumin disease_progression ISO RGD PMID:24370342 RGD:11035281 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461 		JBrowse link
G Ccl3 chemokine (C-C motif) ligand 3 ISO RGD PMID:17298994 RGD:7241819 NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181 		JBrowse link
G Ccn2 cellular communication network factor 2 disease_progression ISO mRNA, protein:increased expression:kidney (rat) RGD PMID:19921985 RGD:150517553 NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581 		JBrowse link
G Clu clusterin treatment ISO RGD PMID:22494435 RGD:9068431 NCBI chr14:66,205,932...66,218,997
Ensembl chr14:66,205,932...66,218,996 		JBrowse link
G Cs citrate synthase treatment ISO RGD PMID:20005400 RGD:243048470 NCBI chr10:128,173,596...128,198,351
Ensembl chr10:128,173,603...128,198,348 		JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO RGD PMID:22845765 RGD:7241226 NCBI chr 9:7,445,822...7,455,975
Ensembl chr 9:7,445,822...7,455,975 		JBrowse link
G Mmp7 matrix metallopeptidase 7 treatment ISO RGD PMID:18209025 RGD:9685339 NCBI chr 9:7,692,091...7,699,586
Ensembl chr 9:7,692,091...7,699,586 		JBrowse link
G Pdgfa platelet derived growth factor, alpha ISO RGD PMID:11889420 RGD:11080974 NCBI chr 5:138,961,769...138,986,336
Ensembl chr 5:138,961,769...138,983,125 		JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide ISO mRNA:increased expression:kidney: RGD PMID:15785371 PMID:11889420 RGD:10449491, RGD:11080974 NCBI chr15:79,880,066...79,899,178
Ensembl chr15:79,880,075...79,899,178 		JBrowse link
G Pdgfra platelet derived growth factor receptor, alpha polypeptide ISO RGD PMID:11889420 RGD:11080974 NCBI chr 5:75,311,988...75,358,867
Ensembl chr 5:75,312,953...75,358,876 		JBrowse link
G Pdgfrb platelet derived growth factor receptor, beta polypeptide ISO RGD PMID:11889420 RGD:11080974 NCBI chr18:61,178,194...61,218,139
Ensembl chr18:61,178,222...61,218,133 		JBrowse link
G Plau plasminogen activator, urokinase ISO protein:increased secretion:T lymphocyte (human) RGD PMID:16387096 RGD:7241259 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO protein:increased expression:kidney: RGD PMID:16221712 RGD:13208600 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360 		JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 treatment ISO protein:increased expression:kidney: RGD PMID:16221712 PMID:18192922 RGD:13208600, RGD:13208601 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122 		JBrowse link
Chronic Lung Allograft Dysfunction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epas1 endothelial PAS domain protein 1 ISO mRNA:increased expression:lung RGD PMID:22305384 RGD:10395369 NCBI chr17:87,061,292...87,140,838
Ensembl chr17:87,061,128...87,140,838 		JBrowse link
Gastric Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kit KIT proto-oncogene receptor tyrosine kinase ISO mRNA,protein:decreased expression:stomach: RGD PMID:20040059 RGD:12911222 NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382 		JBrowse link
G Kitl kit ligand ISO mRNA:decreased expression:stomach: RGD PMID:20040059 RGD:12911222 NCBI chr10:99,851,477...99,936,278
Ensembl chr10:99,851,492...99,936,278 		JBrowse link
Intestinal Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 ISO RGD PMID:15001561 RGD:13515113 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790 		JBrowse link
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) ISO protein:increased expression:plasma RGD PMID:15001561 RGD:13515113 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445 		JBrowse link
G Atp5f1d ATP synthase F1 subunit delta treatment ISO RGD PMID:24232000 RGD:13792678 NCBI chr10:79,974,451...79,981,662
Ensembl chr10:79,974,466...79,981,652 		JBrowse link
G Casp3 caspase 3 treatment ISO RGD PMID:23946597 RGD:13782356 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp9 caspase 9 treatment ISO RGD PMID:23946597 RGD:13782356 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287 		JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 ISO mRNA:increased expression:small intestine RGD PMID:18475188 RGD:2307016 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Cd14 CD14 antigen ISO protein:increased expression:heart, kidney, liver, lung RGD PMID:22493902 RGD:9685194 NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851 		JBrowse link
G Cldn1 claudin 1 ISO protein:decreased expression:colon: RGD PMID:19929946 RGD:2325127 NCBI chr16:26,175,395...26,190,589
Ensembl chr16:26,175,392...26,190,591 		JBrowse link
G Cldn3 claudin 3 ISO protein:decreased expression:colon: RGD PMID:19929946 RGD:2325127 NCBI chr 5:135,015,068...135,016,330
Ensembl chr 5:135,015,068...135,016,326 		JBrowse link
G Cldn5 claudin 5 ISO protein:decreased expression:colon: RGD PMID:19929946 RGD:2325127 NCBI chr16:18,595,597...18,597,012
Ensembl chr16:18,595,597...18,597,012 		JBrowse link
G Crp C-reactive protein, pentraxin-related ISO protein:increased expression:intestine: RGD PMID:17981193 RGD:5129536 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598 		JBrowse link
G Csf3 colony stimulating factor 3 (granulocyte) treatment ISO RGD PMID:9117128 RGD:11039476 NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455 		JBrowse link
G F7 coagulation factor VII ISO human protein in a rat model RGD PMID:22920553 RGD:11041662 NCBI chr 8:13,075,499...13,085,809
Ensembl chr 8:13,076,034...13,085,809 		JBrowse link
G Fasl Fas ligand (TNF superfamily, member 6) treatment ISO RGD PMID:29170412 RGD:13792603 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064 		JBrowse link
G Hmgb1 high mobility group box 1 ISO RGD PMID:22093738 RGD:10402181 NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299 		JBrowse link
G Hmox1 heme oxygenase 1 treatment ISO RGD PMID:19362701 RGD:10766423 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hp haptoglobin treatment ISO RGD PMID:11922743 RGD:11041790 NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804 		JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO RGD PMID:12095141 RGD:11522715 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113 		JBrowse link
G Il6 interleukin 6 treatment ISO RGD PMID:11959089 RGD:11062110 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Jak2 Janus kinase 2 ISO RGD PMID:22777122 RGD:10403072 NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480 		JBrowse link
G Lbp lipopolysaccharide binding protein ISO protein:increased expression:heart, kidney, liver, lung RGD PMID:22493902 RGD:9685194 NCBI chr 2:158,148,413...158,174,772
Ensembl chr 2:158,148,413...158,174,772 		JBrowse link
G Mbl2 mannose-binding lectin (protein C) 2 severity ISO DNA:polymorphisms:exon: RGD PMID:19477015 RGD:12910933 NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087 		JBrowse link
G Mir155 microRNA 155 IEP miRNA:increased expression:Peyer's patch RGD PMID:30206757 RGD:21409753 NCBI chr16:84,511,028...84,511,092
Ensembl chr16:84,511,028...84,511,092 		JBrowse link
G Mir21a microRNA 21a ISO RGD PMID:30309483 RGD:41410822 NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell treatment ISO RGD PMID:16610051 RGD:7777112 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 treatment ISO RGD PMID:28382390 RGD:13440093 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 disease_progression ISO mRNA:decreased expression:liver (rat) RGD PMID:23331901 RGD:15042883 NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447 		JBrowse link
G Parg poly (ADP-ribose) glycohydrolase treatment IMP RGD PMID:15791006 RGD:13514040 NCBI chr14:31,923,900...32,020,671
Ensembl chr14:31,923,906...32,019,507 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A ISO mRNA:increased expression:jejunum (human) RGD PMID:20965186 RGD:9999150 NCBI chr 7:45,172,341...45,175,692
Ensembl chr 7:45,172,340...45,175,692 		JBrowse link
G Proc protein C treatment ISO RGD PMID:15187522 RGD:11250409 NCBI chr18:32,256,179...32,272,623
Ensembl chr18:32,256,179...32,272,623 		JBrowse link
G Serpinc1 serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 treatment ISO RGD PMID:21046505 RGD:11035258 NCBI chr 1:160,806,153...160,830,113
Ensembl chr 1:160,806,155...160,833,433 		JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 ISO protein:increased activity:plasma (rat) RGD PMID:12717359 RGD:11081012 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 treatment ISO RGD PMID:27538408 RGD:151347179 NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400 		JBrowse link
G Traf6 TNF receptor-associated factor 6 ISO RGD PMID:27538408 RGD:151347179 NCBI chr 2:101,508,765...101,532,013
Ensembl chr 2:101,508,774...101,532,014 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 ameliorates ISO associated with mesenteric vascular occlusion; RGD PMID:18091551 RGD:127284848 NCBI chr17:48,539,763...48,553,955
Ensembl chr17:48,539,796...48,553,952 		JBrowse link
G Vwf Von Willebrand factor ISO protein:increased expression:plasma: RGD PMID:10365842 RGD:11080742 NCBI chr 6:125,529,911...125,663,642
Ensembl chr 6:125,523,737...125,663,642 		JBrowse link
G Xdh xanthine dehydrogenase treatment ISO RGD PMID:23010742 RGD:13209016 NCBI chr17:74,190,890...74,257,369
Ensembl chr17:74,190,890...74,257,191 		JBrowse link
Kidney Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 ISO RGD PMID:21680852 RGD:6893484 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790 		JBrowse link
G Ace2 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 ISO mRNA:decreased expression:kidney RGD PMID:20528771 RGD:9685432 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416 		JBrowse link
G Acvr2b activin receptor IIB treatment ISO human construct in rat model RGD PMID:27732750 RGD:329322881 NCBI chr 9:119,231,081...119,271,214
Ensembl chr 9:119,231,184...119,264,061 		JBrowse link
G Adam17 a disintegrin and metallopeptidase domain 17 treatment ISO RGD PMID:22015440 RGD:13703100 NCBI chr12:21,373,510...21,423,633
Ensembl chr12:21,373,510...21,423,633 		JBrowse link
G Adam2 a disintegrin and metallopeptidase domain 2 ISO RGD PMID:11967014 RGD:10047130 NCBI chr14:66,264,771...66,315,300
Ensembl chr14:66,264,778...66,315,182 		JBrowse link
G Adamts1 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 ISO RGD PMID:18272597 RGD:9684850 NCBI chr16:85,590,715...85,600,001
Ensembl chr16:85,590,715...85,600,001 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing treatment ISO RGD PMID:21412771 RGD:8695946 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778 		JBrowse link
G Adm adrenomedullin treatment ISO protein:increased expression:serum: RGD PMID:20538296 PMID:20538296 RGD:7364948, RGD:7364948 NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027 		JBrowse link
G Akr1a1 aldo-keto reductase family 1, member A1 (aldehyde reductase) IMP RGD PMID:31089212 RGD:27226686 NCBI chr 4:116,493,707...116,508,871
Ensembl chr 4:116,493,707...116,508,877 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial IMP RGD PMID:22022451 RGD:7241603 NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887 		JBrowse link
G Anxa1 annexin A1 treatment ISO RGD PMID:20953576 RGD:7421585 NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308 		JBrowse link
G Anxa5 annexin A5 ISO RGD PMID:21918686 RGD:7242028 NCBI chr 3:36,503,072...36,530,036
Ensembl chr 3:36,503,072...36,530,043 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 treatment ISO RGD PMID:26362957 RGD:13703110 NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632 		JBrowse link
G Apoa1 apolipoprotein A-I treatment ISO RGD PMID:18535924 RGD:7241574 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764 		JBrowse link
G Atm ataxia telangiectasia mutated ISO protein:increased expression:kidney RGD PMID:22768306 RGD:10053607 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G Bax BCL2-associated X protein treatment ISO RGD PMID:23151253 RGD:10054101 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 treatment ISO RGD PMID:18221257 PMID:29285062 RGD:2293026, RGD:13792599 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Bdkrb1 bradykinin receptor, beta 1 IMP RGD PMID:18725957 RGD:7241559 NCBI chr12:105,570,350...105,571,770
Ensembl chr12:105,569,344...105,571,687 		JBrowse link
G Becn1 beclin 1, autophagy related treatment ISO RGD PMID:26412257 RGD:11561958 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112 		JBrowse link
G Bmi1 Bmi1 polycomb ring finger oncogene IEP mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr 2:18,681,953...18,691,440
Ensembl chr 2:18,681,829...18,691,440 		JBrowse link
G Bnip3 BCL2/adenovirus E1B interacting protein 3 ISO mRNA, protein:increased expression:kidney RGD PMID:23698117 RGD:11561968 NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248 		JBrowse link
G C3 complement component 3 treatment ISO RGD PMID:19691975 RGD:7411689 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha ISO RGD PMID:19194162 RGD:7204479 NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592 		JBrowse link
G Casp3 caspase 3 treatment ISO RGD PMID:23151253 RGD:10054101 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp7 caspase 7 ISO RGD PMID:17596683 RGD:5684536 NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776 		JBrowse link
G Ccl11 chemokine (C-C motif) ligand 11 treatment IDA RGD PMID:22160777 RGD:7247742 NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781 		JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 treatment IEP
ISO		 mRNA, protein:increased expression:kidney, lung, serum RGD PMID:20396927 PMID:18650485 RGD:4891433, RGD:11526113 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Cd14 CD14 antigen IEP mRNA,protein:increased expression:kidney RGD PMID:10966493 RGD:7204444 NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851 		JBrowse link
G Cd40 CD40 antigen treatment ISO RGD PMID:25993320 RGD:11251055 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868 		JBrowse link
G Cfb complement factor B IMP RGD PMID:16467447 PMID:12538716 RGD:7242709, RGD:7242734 NCBI chr17:35,075,350...35,081,492
Ensembl chr17:35,075,350...35,081,494 		JBrowse link
G Cfh complement component factor h treatment ISO protein:decreased expression:serum: RGD PMID:20538296 PMID:20538296 RGD:7364948, RGD:7364948 NCBI chr 1:140,013,593...140,111,149
Ensembl chr 1:140,012,446...140,111,502 		JBrowse link
G Ciita class II transactivator IEP RGD PMID:14569092 RGD:7242896 NCBI chr16:10,297,877...10,348,928
Ensembl chr16:10,297,923...10,346,282 		JBrowse link
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 IEP mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr  X:101,290,984...101,295,787
Ensembl chr  X:101,290,987...101,295,787 		JBrowse link
G Csf1 colony stimulating factor 1 (macrophage) IMP
ISO		 mRNA:increased expression:kidney RGD PMID:23143303 PMID:19196448 RGD:7257565, RGD:7257570 NCBI chr 3:107,648,364...107,668,048
Ensembl chr 3:107,648,364...107,667,785 		JBrowse link
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:23143303 RGD:7257565 NCBI chr18:61,238,644...61,264,211
Ensembl chr18:61,233,670...61,265,221 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 IMP
ISO		 RGD PMID:22189844 PMID:9407517 RGD:7204675, RGD:7204727 NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991 		JBrowse link
G Cxcr2 chemokine (C-X-C motif) receptor 2 IMP RGD PMID:20038794 RGD:7257679 NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,148...74,200,405 		JBrowse link
G Cxcr4 chemokine (C-X-C motif) receptor 4 ISO protein:increased expression:kidney RGD PMID:29073721 RGD:13825150 NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 treatment ISO RGD PMID:23552495 RGD:7244372 NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394 		JBrowse link
G Daxx Fas death domain-associated protein IEP
ISO		 protein:increased expression:kidney: RGD PMID:18480747 PMID:18480747 RGD:9587836, RGD:9587836 NCBI chr17:34,128,379...34,134,564
Ensembl chr17:34,128,388...34,134,564 		JBrowse link
G Ddr1 discoidin domain receptor family, member 1 IEP protein:increased expression:kidney (mouse) RGD PMID:31383731 RGD:151347540 NCBI chr17:35,992,459...36,015,633
Ensembl chr17:35,992,459...36,015,513 		JBrowse link
G Dhfr dihydrofolate reductase ISO mRNA,protein:decreased expression:kidney: RGD PMID:18408363 RGD:11040540 NCBI chr13:92,491,291...92,525,561
Ensembl chr13:92,491,234...92,525,561 		JBrowse link
G Drd3 dopamine receptor D3 treatment ISO RGD PMID:25989500 RGD:13506961 NCBI chr16:43,574,285...43,646,353
Ensembl chr16:43,574,389...43,643,295 		JBrowse link
G Eed embryonic ectoderm development IEP mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr 7:89,603,862...89,630,184
Ensembl chr 7:89,603,862...89,630,191 		JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 ISO mRNA, protein:decreased expression:kidney RGD PMID:19349364 RGD:11252083 NCBI chr 8:125,635,325...125,676,063
Ensembl chr 8:125,635,326...125,676,063 		JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 ISO mRNA, protein:decreased expression:kidney RGD PMID:19349364 RGD:11252083 NCBI chr12:54,225,767...54,250,660
Ensembl chr12:54,225,767...54,250,646 		JBrowse link
G Elane elastase, neutrophil expressed treatment ISO RGD PMID:16980042 RGD:10450580 NCBI chr10:79,722,146...79,724,050
Ensembl chr10:79,722,081...79,724,049 		JBrowse link
G Eng endoglin ISO
IMP		 mRNA, protein:increased expression:kidney (rat) RGD PMID:16751653 PMID:16751653 RGD:7248779, RGD:7248779 NCBI chr 2:32,536,607...32,572,681
Ensembl chr 2:32,536,607...32,572,681 		JBrowse link
G Ep300 E1A binding protein p300 ISO protein:altered localization:kidney (rat) RGD PMID:23936185 RGD:7257563 NCBI chr15:81,470,329...81,536,278
Ensembl chr15:81,469,552...81,536,278 		JBrowse link
G Epo erythropoietin treatment ISO RGD PMID:19961832 PMID:25581532 RGD:10401077, RGD:11041698 NCBI chr 5:137,481,282...137,484,078
Ensembl chr 5:137,481,282...137,531,504 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit IEP mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr 6:47,507,208...47,613,843
Ensembl chr 6:47,507,073...47,572,275 		JBrowse link
G F3 coagulation factor III ISO protein:decreased expression:lung RGD PMID:25883098 RGD:11341735 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697 		JBrowse link
G Fas Fas (TNF receptor superfamily member 6) treatment ISO RGD PMID:29285062 RGD:13792599 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Fasl Fas ligand (TNF superfamily, member 6) treatment ISO RGD PMID:29285062 RGD:13792599 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064 		JBrowse link
G Fcgr1 Fc receptor, IgG, high affinity I treatment ISO RGD PMID:22402584 RGD:9685699 NCBI chr 3:96,190,225...96,201,285
Ensembl chr 3:96,190,225...96,201,285 		JBrowse link
G Fga fibrinogen alpha chain ISO mRNA,protein:increased expression:kidney RGD PMID:21685370 RGD:7175292 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934 		JBrowse link
G Fgb fibrinogen beta chain treatment ISO mRNA, protein:increased expression:kidney RGD PMID:21685370 PMID:21685370 RGD:7175292, RGD:7175292 NCBI chr 3:82,949,553...82,957,170
Ensembl chr 3:82,947,448...82,957,170 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 exacerbates
ameliorates		 IEP
ISO
IMP		 protein:increased phosphorylation:kidney (mouse) RGD PMID:20591940 PMID:22688984 PMID:29344510 PMID:32523960 RGD:155663667, RGD:155882537, RGD:155782904, RGD:155782882 NCBI chr 7:129,764,181...129,868,538
Ensembl chr 7:129,764,181...132,725,079 		JBrowse link
G Fgg fibrinogen gamma chain ISO mRNA,protein:increased expression:kidney RGD PMID:21685370 RGD:7175292 NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356 		JBrowse link
G Fn1 fibronectin 1 ISO RGD PMID:11352844 RGD:7205629 NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359 		JBrowse link
G Fos FBJ osteosarcoma oncogene IEP RGD PMID:19095962 RGD:7242184 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047 		JBrowse link
G Gfer growth factor, augmenter of liver regeneration treatment ISO protein:increased expression:kidney: RGD PMID:20332418 PMID:20332418 RGD:9685723, RGD:9685723 NCBI chr17:24,912,164...24,915,065
Ensembl chr17:24,912,161...24,915,130 		JBrowse link
G Glo1 glyoxalase 1 ISO RGD PMID:19211689 PMID:19211689 RGD:7242566, RGD:7242566 NCBI chr17:30,811,835...30,831,633
Ensembl chr17:30,803,910...30,845,845 		JBrowse link
G Gsr glutathione reductase treatment ISO RGD PMID:24630969 RGD:10401866 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191 		JBrowse link
G Gstm1 glutathione S-transferase, mu 1 ISO mRNA, protein:decreased expression:kidney RGD PMID:29137244 RGD:158014894 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289 		JBrowse link
G H2ax H2A.X variant histone treatment ISO RGD PMID:23726287 RGD:8693706 NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374 		JBrowse link
G Has1 hyaluronan synthase 1 ISO RGD PMID:22529164 RGD:9588636 NCBI chr17:18,063,588...18,075,450
Ensembl chr17:18,063,585...18,075,467 		JBrowse link
G Has2 hyaluronan synthase 2 ISO RGD PMID:22529164 RGD:9588636 NCBI chr15:56,529,023...56,557,942
Ensembl chr15:56,529,023...56,557,935 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO
IEP		 protein:increased expression:urine: RGD PMID:23552495 PMID:23019274 PMID:23085062 RGD:7244372, RGD:7245495, RGD:7245489 NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit treatment
severity		 ISO RGD PMID:17519789 PMID:22432008 RGD:1626334, RGD:9068883 NCBI chr12:73,948,098...73,994,328
Ensembl chr12:73,948,149...73,994,304 		JBrowse link
G Hmox1 heme oxygenase 1 treatment ISO RGD PMID:21291499 RGD:10755580 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hsf1 heat shock factor 1 ISO protein:increased expression:kidney (rat) RGD PMID:23102208 RGD:10402775 NCBI chr15:76,361,562...76,385,355
Ensembl chr15:76,361,622...76,386,113 		JBrowse link
G Hspa8 heat shock protein 8 ISO RGD PMID:7569112 RGD:7242788 NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383 		JBrowse link
G Hyal1 hyaluronoglucosaminidase 1 ISO RGD PMID:22529164 RGD:9588636 NCBI chr 9:107,454,149...107,458,898
Ensembl chr 9:107,454,126...107,458,909 		JBrowse link
G Hyal2 hyaluronoglucosaminidase 2 ISO RGD PMID:22529164 RGD:9588636 NCBI chr 9:107,445,096...107,449,975
Ensembl chr 9:107,445,144...107,449,978 		JBrowse link
G Ifng interferon gamma treatment IEP RGD PMID:28355607 RGD:14975115 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Igf1r insulin-like growth factor I receptor ISO mRNA: increased expression: kidney: 3 and 5 days post ischemia RGD PMID:10990448 RGD:7242905 NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416 		JBrowse link
G Ikbkb inhibitor of kappaB kinase beta treatment ISO RGD PMID:19546526 RGD:7495779 NCBI chr 8:23,149,221...23,196,605
Ensembl chr 8:23,149,228...23,196,605 		JBrowse link
G Il10 interleukin 10 treatment ISO
IEP		 RGD PMID:24079335 PMID:28664613 RGD:7364864, RGD:14975137 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il18 interleukin 18 treatment ISO RGD PMID:22089199 RGD:8655971 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140 		JBrowse link
G Il1b interleukin 1 beta ISO RGD PMID:20030532 RGD:7175501 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO
IMP		 rat model treated with human protein
mouse model treated with human protein		 RGD PMID:18363573 PMID:9555664 PMID:16849996 RGD:6907101, RGD:6909149, RGD:6907359 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506 		JBrowse link
G Inhbb inhibin beta-B ISO protein:increased expression:serum (rat) RGD PMID:27732750 RGD:329322881 NCBI chr 1:119,343,193...119,349,978
Ensembl chr 1:119,343,195...119,349,978 		JBrowse link
G Itgb2 integrin beta 2 ISO Associated with renal transplant patients RGD PMID:20504838 PMID:11007822 RGD:6907049, RGD:6907073 NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542 		JBrowse link
G Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 ISO protein:decreased expression:kidney RGD PMID:21250976 RGD:7297045 NCBI chr 7:45,746,545...45,750,215
Ensembl chr 7:45,743,377...45,750,188 		JBrowse link
G Kl klotho treatment ISO
IMP		 mRNA,protein:decreased expression:renal tubule: RGD PMID:16204278 PMID:16204278 RGD:10403064, RGD:10403064 NCBI chr 5:150,876,072...150,917,282
Ensembl chr 5:150,876,072...150,917,282 		JBrowse link
G Kmt2a lysine (K)-specific methyltransferase 2A IEP protein:increased expression:kidney (mouse) RGD PMID:31570196 RGD:155888490 NCBI chr 9:44,714,652...44,793,492
Ensembl chr 9:44,714,652...44,792,594 		JBrowse link
G Lcn2 lipocalin 2 ISO
IEP		 protein:increased expression:urine:
mRNA,protein:increased expression:kidney,urine
mRNA,protein:increased expression:kidney:		 RGD PMID:23364806 PMID:27800610 PMID:20181666 PMID:23085062 RGD:7245469, RGD:126790572, RGD:126779563, RGD:7245489 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264 		JBrowse link
G Lep leptin resistance ISO RGD PMID:22969992 RGD:6909133 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876 		JBrowse link
G Lgals3 lectin, galactose binding, soluble 3 ISO mRNA:increased expression:kidney RGD PMID:10980121 RGD:9685228 NCBI chr14:47,611,317...47,623,624
Ensembl chr14:47,605,208...47,623,617 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha treatment IEP
ISO		 RGD PMID:20075199 PMID:26412257 RGD:11561916, RGD:11561958 NCBI chr 2:155,118,284...155,119,993
Ensembl chr 2:155,118,217...155,119,993 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 treatment ISO RGD PMID:23952292 RGD:10412647 NCBI chr10:19,809,847...20,018,496
Ensembl chr10:19,810,218...20,018,499 		JBrowse link
G Mc1r melanocortin 1 receptor ISO protein:decreased expression:kidney outer medulla RGD PMID:18790174 RGD:5687322 NCBI chr 8:124,133,839...124,137,483
Ensembl chr 8:124,133,846...124,137,483 		JBrowse link
G Mir146 microRNA 146 treatment ISO RGD PMID:27760486 RGD:155882556 NCBI chr11:43,265,224...43,265,288
Ensembl chr11:43,265,224...43,265,288 		JBrowse link
G Mir320 microRNA 320 treatment ISO RGD PMID:31089916 PMID:27760486 RGD:155882543, RGD:155882556 NCBI chr14:70,680,950...70,681,031
Ensembl chr14:70,680,950...70,681,031 		JBrowse link
G Mir381 microRNA 381 ISO RNA:decreased expression:kidney RGD PMID:29073721 RGD:13825150 NCBI chr12:109,693,256...109,693,330
Ensembl chr12:109,693,256...109,693,330 		JBrowse link
G Mir423 microRNA 423 treatment ISO RGD PMID:29137244 RGD:158014894 NCBI chr11:76,968,890...76,968,998
Ensembl chr11:76,968,890...76,968,998 		JBrowse link
G Mir494 microRNA 494 ameliorates IMP RGD PMID:23160513 RGD:155883172 NCBI chr12:109,681,752...109,681,836
Ensembl chr12:109,681,752...109,681,836 		JBrowse link
G Mpo myeloperoxidase ISO
IMP		 protein:increased activity:kidney RGD PMID:22950848 PMID:18055546 RGD:6909167, RGD:7174699 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239 		JBrowse link
G Muc1 mucin 1, transmembrane treatment ISO RGD PMID:22019164 RGD:7245959 NCBI chr 3:89,136,363...89,140,688
Ensembl chr 3:89,136,364...89,140,688 		JBrowse link
G Myc myelocytomatosis oncogene ISO mRNA:increased expression:kidney (rat) RGD PMID:17220792 RGD:7207777 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223 		JBrowse link
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 ISO
IEP		 RGD PMID:24096033 PMID:22160772 RGD:13801197, RGD:13801199 NCBI chr19:44,537,010...44,543,881
Ensembl chr19:44,537,011...44,543,879 		JBrowse link
G Nes nestin ISO RGD PMID:24503548 RGD:11570523 NCBI chr 3:87,878,400...87,887,758
Ensembl chr 3:87,878,385...87,887,758 		JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 treatment ISO RGD PMID:31089916 RGD:155882543 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell treatment ISO RGD PMID:29291552 RGD:13504682 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472 		JBrowse link
G Nppa natriuretic peptide type A ISO RGD PMID:20471588 RGD:7247717 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 treatment ISO RGD PMID:21545725 RGD:11035217 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 severity IEP
IMP		 mRNA:increased expression:kidney RGD PMID:22343121 PMID:22343121 RGD:14700869, RGD:14700869 NCBI chr15:101,151,783...101,172,676
Ensembl chr15:101,152,150...101,172,676 		JBrowse link
G Ogg1 8-oxoguanine DNA-glycosylase 1 ISO RGD PMID:12531391 RGD:2317150 NCBI chr 6:113,303,959...113,311,149
Ensembl chr 6:113,303,933...113,312,029 		JBrowse link
G Pax2 paired box 2 ISO mRNA, protein:increased expression:kidney RGD PMID:12444203 RGD:727468 NCBI chr19:44,735,040...44,826,708
Ensembl chr19:44,744,484...44,826,310 		JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide ISO mRNA,protein:increased expression:tubule, S3 segment: RGD PMID:10550325 RGD:8554477 NCBI chr15:79,880,066...79,899,178
Ensembl chr15:79,880,075...79,899,178 		JBrowse link
G Pdgfra platelet derived growth factor receptor, alpha polypeptide ISO mRNA:increased expression:kidney RGD PMID:10550325 RGD:8554477 NCBI chr 5:75,311,988...75,358,867
Ensembl chr 5:75,312,953...75,358,876 		JBrowse link
G Pdgfrb platelet derived growth factor receptor, beta polypeptide ISO mRNA:increased expression:kidney RGD PMID:12819032 PMID:10550325 RGD:1580850, RGD:8554477 NCBI chr18:61,178,194...61,218,139
Ensembl chr18:61,178,222...61,218,133 		JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel ISO protein:increased expression:kidney (rat) RGD PMID:12454224 RGD:1580868 NCBI chr 5:104,599,379...104,653,685
Ensembl chr 5:104,607,316...104,653,685 		JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha treatment ISO RGD PMID:24918615 RGD:10059636 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068 		JBrowse link
G Rnls renalase, FAD-dependent amine oxidase ISO
IMP
IEP		 mRNA,protein:decreased expression:kidney,plasma: RGD PMID:23393318 PMID:23393318 PMID:23393318 RGD:7327166, RGD:7327166, RGD:7327166 NCBI chr19:33,115,140...33,369,695
Ensembl chr19:33,115,147...33,369,665 		JBrowse link
G Serpinc1 serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 severity ISO RGD PMID:26108065 PMID:26108065 RGD:11354006, RGD:11354006 NCBI chr 1:160,806,153...160,830,113
Ensembl chr 1:160,806,155...160,833,433 		JBrowse link
G Shh sonic hedgehog IEP mRNA, protein:increased expression:kidney RGD PMID:24744439 RGD:12859042 NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254 		JBrowse link
G Sirt1 sirtuin 1 treatment ISO RGD PMID:22324445 RGD:9495930 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483 		JBrowse link
G Six2 sine oculis-related homeobox 2 IEP mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr17:85,970,276...85,995,682
Ensembl chr17:85,991,705...85,995,702 		JBrowse link
G Slc22a1 solute carrier family 22 (organic cation transporter), member 1 ISO RGD PMID:21835768 RGD:7243877 NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716 		JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 ISO RGD PMID:21835768 RGD:7243877 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375 		JBrowse link
G Slc34a1 solute carrier family 34 (sodium phosphate), member 1 ISO protein:decreased expression:renal proximal tubule, brush border membrane (rat) RGD PMID:15775707 RGD:2311304 NCBI chr13:55,547,435...55,562,508
Ensembl chr13:55,546,000...55,563,405 		JBrowse link
G Src Rous sarcoma oncogene ISO RGD PMID:12819032 RGD:1580850 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 severity IMP RGD PMID:12709397 RGD:7244143 NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826 		JBrowse link
G Suz12 SUZ12 polycomb repressive complex 2 subunit IEP mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr11:79,883,932...79,924,949
Ensembl chr11:79,883,932...79,924,949 		JBrowse link
G Tfpi tissue factor pathway inhibitor ISO RGD PMID:11796005 RGD:11062062 NCBI chr 2:84,263,199...84,307,119
Ensembl chr 2:84,263,199...84,307,119 		JBrowse link
G Tlr2 toll-like receptor 2 treatment
severity		 ISO
IEP
IMP
IDA		 RGD PMID:23239000 PMID:11801667 PMID:20130923 PMID:22750071 PMID:23023072 RGD:7207892, RGD:7241087, RGD:7240552, RGD:7207896, RGD:7207894 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074 		JBrowse link
G Tlr4 toll-like receptor 4 treatment ISO
IEP
IMP		 RGD PMID:23239000 PMID:11801667 PMID:20130923 RGD:7207892, RGD:7241087, RGD:7240552 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
G Tnf tumor necrosis factor ISO protein:increased expression:serum RGD PMID:19925291 RGD:2315112 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a IEP mRNA:increased expression:lung RGD PMID:22728466 RGD:7245543 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO protein:increased expression:kidney RGD PMID:20164827 RGD:7240507 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337 		JBrowse link
G Vwf Von Willebrand factor ISO protein:increased expression:serum: RGD PMID:12684225 RGD:11080744 NCBI chr 6:125,529,911...125,663,642
Ensembl chr 6:125,523,737...125,663,642 		JBrowse link
G Wt1 WT1 transcription factor IEP mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr 2:104,956,874...105,003,959
Ensembl chr 2:104,956,874...105,003,961 		JBrowse link
G Xdh xanthine dehydrogenase treatment ISO associated with Diabetes Mellitus, Type 2 RGD PMID:22995295 PMID:20616412 RGD:7247637, RGD:7247695 NCBI chr17:74,190,890...74,257,369
Ensembl chr17:74,190,890...74,257,191 		JBrowse link
Liver Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing treatment ISO RGD PMID:23762489 RGD:8695935 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778 		JBrowse link
G Adm adrenomedullin treatment ISO mRNA,protein:increased expression:liver,plasma: RGD PMID:19212187 PMID:19212187 RGD:7364958, RGD:7364958 NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027 		JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO mRNA:increased expression:liver RGD PMID:21431875 RGD:10402078 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial treatment IMP
ISO		 protein:altered expression:liver (mouse)
protein:altered expression:liver (rat)		 RGD PMID:30671488 PMID:29589772 RGD:15036807, RGD:14975297 NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887 		JBrowse link
G Bad BCL2-associated agonist of cell death treatment ISO mRNA:increased expression:liver
associated with Non-alcoholic Fatty Liver Disease		 RGD PMID:22647552 PMID:22847887 RGD:10053673, RGD:10053710 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267 		JBrowse link
G Bax BCL2-associated X protein treatment ISO mRNA:increased expression:liver
associated with Non-alcoholic Fatty Liver Disease		 RGD PMID:22647552 PMID:21092002 PMID:22847887 RGD:10053673, RGD:5134995, RGD:10053710 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 treatment ISO associated with Non-alcoholic Fatty Liver Disease RGD PMID:22847887 PMID:21092002 RGD:10053710, RGD:5134995 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Bcl2l1 BCL2-like 1 treatment ISO associated with Non-alcoholic Fatty Liver Disease RGD PMID:22847887 RGD:10053710 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648 		JBrowse link
G C3 complement component 3 treatment ISO RGD PMID:19854450 RGD:11040888 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G Casp12 caspase 12 treatment ISO RGD PMID:29428101 RGD:13782166 NCBI chr 9:5,345,419...5,373,034
Ensembl chr 9:5,345,430...5,373,032 		JBrowse link
G Casp8 caspase 8 treatment ISO
IMP		 RGD PMID:23423194 PMID:15300206 RGD:8661760, RGD:14695087 NCBI chr 1:58,834,398...58,886,662
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Casp9 caspase 9 treatment ISO RGD PMID:23364428 RGD:13782358 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287 		JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 treatment
severity		 ISO
IMP		 mRNA, protein:increased expression:liver, serum (rat) RGD PMID:9500701 PMID:10630515 PMID:27229110 RGD:8549627, RGD:14995929, RGD:14995460 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Ccl5 chemokine (C-C motif) ligand 5 treatment
severity		 IMP
IDA		 RGD PMID:28623253 PMID:28623253 RGD:14995305, RGD:14995305 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344 		JBrowse link
G Ccr2 chemokine (C-C motif) receptor 2 severity IMP RGD PMID:27229110 RGD:14995460 NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594 		JBrowse link
G Cd14 CD14 antigen ISO RGD PMID:22564590 RGD:7183676 NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851 		JBrowse link
G Cd40 CD40 antigen treatment ISO RGD PMID:14741776 RGD:8547795 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868 		JBrowse link
G Cfh complement component factor h treatment ISO mRNA,protein:decreased expression:liver,plasma: RGD PMID:19212187 PMID:19212187 RGD:7364958, RGD:7364958 NCBI chr 1:140,013,593...140,111,149
Ensembl chr 1:140,012,446...140,111,502 		JBrowse link
G Cs citrate synthase ISO RGD PMID:25416448 RGD:13504849 NCBI chr10:128,173,596...128,198,351
Ensembl chr10:128,173,603...128,198,348 		JBrowse link
G Cxcl1 chemokine (C-X-C motif) ligand 1 treatment ISO RGD PMID:21092002 PMID:21092002 RGD:5134995, RGD:5134995 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974 		JBrowse link
G Cxcl10 chemokine (C-X-C motif) ligand 10 treatment IMP RGD PMID:18041715 RGD:27095942 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO mRNA:decreased expression:lung RGD PMID:19595018 RGD:2314952 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Elane elastase, neutrophil expressed ISO RGD PMID:10588515 RGD:10450560 NCBI chr10:79,722,146...79,724,050
Ensembl chr10:79,722,081...79,724,049 		JBrowse link
G Epo erythropoietin treatment ISO RGD PMID:25769561 RGD:15090809 NCBI chr 5:137,481,282...137,484,078
Ensembl chr 5:137,481,282...137,531,504 		JBrowse link
G Epor erythropoietin receptor ISO protein:increased phosphorylation:liver: RGD PMID:25769561 RGD:15090809 NCBI chr 9:21,870,193...21,874,915
Ensembl chr 9:21,870,193...21,874,802 		JBrowse link
G F3 coagulation factor III treatment ISO RGD PMID:11750579 RGD:11341708 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697 		JBrowse link
G Fadd Fas (TNFRSF6)-associated via death domain treatment ISO RGD PMID:23423194 RGD:8661760 NCBI chr 7:144,132,060...144,136,178
Ensembl chr 7:144,131,055...144,136,200 		JBrowse link
G Fas Fas (TNF receptor superfamily member 6) treatment ISO protein:increased expression:liver RGD PMID:17235585 PMID:18561025 PMID:16222447 RGD:2290283, RGD:14700680, RGD:1600351 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Fasl Fas ligand (TNF superfamily, member 6) treatment ISO RGD PMID:18561025 RGD:14700680 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064 		JBrowse link
G Fga fibrinogen alpha chain ISO mRNA:increased expression:liver (rat) RGD PMID:23503399 RGD:9685021 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934 		JBrowse link
G Fn1 fibronectin 1 ISO RGD PMID:12651615 RGD:7205470 NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment ISO associated with nonalcoholic fatty liver disease RGD PMID:28807209 RGD:13792730 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446 		JBrowse link
G Gstm1 glutathione S-transferase, mu 1 ISO mRNA:decreased expression:lung RGD PMID:19595018 RGD:2314952 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289 		JBrowse link
G H2ax H2A.X variant histone treatment ISO RGD PMID:23792534 RGD:8693718 NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374 		JBrowse link
G Hmgb1 high mobility group box 1 treatment ISO protein:increased oxidation:liver
mRNA, protein:increased expression, altered localization:serum, hepatocyte, cytoplasm		 RGD PMID:24578610 PMID:22514737 PMID:21431875 RGD:10402068, RGD:10402175, RGD:10402078 NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299 		JBrowse link
G Hmox1 heme oxygenase 1 treatment ISO RGD PMID:20446775 RGD:10755725 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hp haptoglobin treatment ISO RGD PMID:17187421 PMID:21699906 RGD:1626366, RGD:11041815 NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804 		JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment ISO associated with Intestinal Reperfusion Injury;protein:increased expression:liver RGD PMID:7884306 PMID:8780571 RGD:11520784, RGD:14402044 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113 		JBrowse link
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial severity IMP RGD PMID:28938192 RGD:14985248 NCBI chr 7:79,744,594...79,768,356
Ensembl chr 7:79,744,594...79,765,140 		JBrowse link
G Ikbkg inhibitor of kappaB kinase gamma treatment ISO RGD PMID:22381173 RGD:12791280 NCBI chr  X:73,436,883...73,498,013
Ensembl chr  X:73,436,896...73,497,460 		JBrowse link
G Il10 interleukin 10 treatment ISO RGD PMID:21911118 RGD:7364839 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il18 interleukin 18 treatment ISO
IMP		 RGD PMID:25919765 PMID:14999688 RGD:14696667, RGD:14696668 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140 		JBrowse link
G Il18bp interleukin 18 binding protein ISO mRNA,protein:increased expression:liver RGD PMID:25919765 RGD:14696667 NCBI chr 7:101,664,281...101,669,699
Ensembl chr 7:101,664,092...101,667,897 		JBrowse link
G Il1a interleukin 1 alpha treatment ISO mRNA:increased expression:lung
protein:increased expression:serum		 RGD PMID:19595018 PMID:9840148 PMID:19283466 RGD:2314952, RGD:11059517, RGD:6907377 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892 		JBrowse link
G Il1b interleukin 1 beta treatment ISO
IEP		 associated with Cholestasis RGD PMID:21468628 PMID:32155285 RGD:7175318, RGD:155260323 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO rat model treated with human protein RGD PMID:9000676 PMID:12451245 RGD:6909138, RGD:8551710 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506 		JBrowse link
G Il6 interleukin 6 treatment ISO
IEP		 RGD PMID:24752458 PMID:32155285 RGD:11062134, RGD:155260323 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Jak2 Janus kinase 2 treatment ISO RGD PMID:22288937 RGD:10403073 NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480 		JBrowse link
G Lbp lipopolysaccharide binding protein ISO mRNA, protein:increased expression:liver RGD PMID:12134092 RGD:9685192 NCBI chr 2:158,148,413...158,174,772
Ensembl chr 2:158,148,413...158,174,772 		JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 ameliorates
exacerbates		 IMP
IEP		 protein:increased phosphorylation:liver (mouse) RGD PMID:30076625 PMID:30622220 RGD:155804280, RGD:155882441 NCBI chr 4:31,963,659...32,023,470
Ensembl chr 4:31,964,097...32,023,467 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 ISO protein:increased activity:liver: RGD PMID:11679968 RGD:10412680 NCBI chr14:33,099,855...33,169,215
Ensembl chr14:33,099,855...33,169,115 		JBrowse link
G Mfn2 mitofusin 2 treatment ISO mRNA, protein:decreased expression:liver (rat) RGD PMID:27363631 PMID:24898700 RGD:12910833, RGD:13204829 NCBI chr 4:147,958,043...147,989,527
Ensembl chr 4:147,958,056...147,989,161 		JBrowse link
G Mir145a microRNA 145a ISO mRNA:decreased expression:small intestine (rat) RGD PMID:23166305 RGD:155230822 NCBI chr18:61,780,896...61,780,965
Ensembl chr18:61,780,896...61,780,965 		JBrowse link
G Mir155 microRNA 155 IMP RGD PMID:28640790 RGD:21079442 NCBI chr16:84,511,028...84,511,092
Ensembl chr16:84,511,028...84,511,092 		JBrowse link
G Mir210 microRNA 210 treatment IEP RGD PMID:32155285 RGD:155260323 NCBI chr 7:140,801,297...140,801,406
Ensembl chr 7:140,801,297...140,801,406 		JBrowse link
G Mir21a microRNA 21a ISO RNA:increased expression:liver RGD PMID:29187695 RGD:41410824 NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984 		JBrowse link
G Mir223 microRNA 223 IEP RNA:increased expression:liver
RNA:increased expression:serum,liver		 RGD PMID:19104939 PMID:28646120 RGD:13831297, RGD:21408574 NCBI chr  X:95,286,423...95,286,532
Ensembl chr  X:95,286,423...95,286,532 		JBrowse link
G Mir34a microRNA 34a ISO miRNA:increased expression:liver RGD PMID:28963950 RGD:14695005 NCBI chr 4:150,152,911...150,153,012
Ensembl chr 4:150,152,911...150,153,012 		JBrowse link
G Mmp15 matrix metallopeptidase 15 ISO mRNA:increased expression:lung RGD PMID:19595018 RGD:2314952 NCBI chr 8:96,078,924...96,100,921
Ensembl chr 8:96,078,896...96,101,708 		JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment ISO associated with Fatty Liver;mRNA, protein:decreased expression, decreased activity:liver RGD PMID:17255325 RGD:8547976 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770 		JBrowse link
G Muc1 mucin 1, transmembrane ISO mRNA, protein:decreased expression:bile duct RGD PMID:21775928 RGD:7364757 NCBI chr 3:89,136,363...89,140,688
Ensembl chr 3:89,136,364...89,140,688 		JBrowse link
G Muc17 mucin 17, cell surface associated ISO mRNA, protein:decreased expression:bile duct RGD PMID:21775928 RGD:7364757 NCBI chr 5:137,163,772...137,202,809
Ensembl chr 5:137,163,770...137,202,830 		JBrowse link
G Muc4 mucin 4 ISO mRNA:decreased expression:bile duct RGD PMID:21775928 RGD:7364757 NCBI chr16:32,555,089...32,602,761
Ensembl chr16:32,555,015...32,602,754 		JBrowse link
G Nfatc1 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 IEP mRNA,protein:increased expression:liver: RGD PMID:36092961 RGD:268357360 NCBI chr18:80,649,418...80,756,286
Ensembl chr18:80,649,420...80,756,286 		JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 treatment ISO RGD PMID:22288937 PMID:31952110 RGD:10403073, RGD:21201304 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell treatment ISO RGD PMID:28966130 RGD:13450941 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472 		JBrowse link
G Proc protein C treatment ISO RGD PMID:12605111 PMID:18507760 RGD:11100021, RGD:11100046 NCBI chr18:32,256,179...32,272,623
Ensembl chr18:32,256,179...32,272,623 		JBrowse link
G Serpinc1 serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 treatment ISO RGD PMID:24726586 PMID:8589354 RGD:10450597, RGD:11038771 NCBI chr 1:160,806,153...160,830,113
Ensembl chr 1:160,806,155...160,833,433 		JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 ISO protein:increased activity:plasma (rat) RGD PMID:12353078 RGD:8547901 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122 		JBrowse link
G Serping1 serine (or cysteine) peptidase inhibitor, clade G, member 1 treatment ISO RGD PMID:16367929 RGD:1580273 NCBI chr 2:84,595,704...84,605,778
Ensembl chr 2:84,595,731...84,605,788 		JBrowse link
G Sirt1 sirtuin 1 treatment ISO RGD PMID:24557422 RGD:9497542 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483 		JBrowse link
G Slpi secretory leukocyte peptidase inhibitor ISO RGD PMID:19595018 RGD:2314952 NCBI chr 2:164,195,990...164,231,086
Ensembl chr 2:164,195,990...164,231,015 		JBrowse link
G Sod1 superoxide dismutase 1, soluble treatment ISO human gene in a rat model RGD PMID:16555330 PMID:11779401 RGD:8655889, RGD:1581095 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217 		JBrowse link
G Sod3 superoxide dismutase 3, extracellular treatment ISO human gene in a rat model RGD PMID:11779401 RGD:1581095 NCBI chr 5:52,521,146...52,527,080
Ensembl chr 5:52,521,133...52,528,760 		JBrowse link
G Tert telomerase reverse transcriptase treatment ISO RGD PMID:19545665 RGD:11038676 NCBI chr13:73,775,030...73,797,962
Ensembl chr13:73,775,030...73,797,962 		JBrowse link
G Tfpi tissue factor pathway inhibitor ISO RGD PMID:9921794 RGD:11062061 NCBI chr 2:84,263,199...84,307,119
Ensembl chr 2:84,263,199...84,307,119 		JBrowse link
G Tlr2 toll-like receptor 2 treatment IEP
ISO		 RGD PMID:16038046 PMID:25769561 RGD:15090805, RGD:15090809 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074 		JBrowse link
G Tlr4 toll-like receptor 4 treatment
severity		 ISO
IEP
IMP		 mRNA:increased expression:liver
protein:increased expression:membrane raft:		 RGD PMID:21431875 PMID:21693218 PMID:22797797 PMID:23395256 PMID:27064547 RGD:10402078, RGD:5685379, RGD:14697702, RGD:14697699, RGD:14697698 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
G Tnf tumor necrosis factor treatment ISO
IEP		 protein:increased expression:serum (rat) RGD PMID:24726586 PMID:32155285 PMID:11592783 PMID:19357028 PMID:11129814 More... RGD:10450597, RGD:155260323, RGD:2325259, RGD:15039406, RGD:14995473, RGD:14995447, RGD:14985258, RGD:14985257, RGD:14696803 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a ISO protein:increased localization:mitochondrion RGD PMID:23423194 RGD:8661760 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447 		JBrowse link
G Tradd TNFRSF1A-associated via death domain treatment ISO RGD PMID:23423194 RGD:8661760 NCBI chr 8:105,985,207...105,991,226
Ensembl chr 8:105,984,918...105,991,241 		JBrowse link
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) ISO mRNA:increased expression:liver RGD PMID:22195248 RGD:7175309 NCBI chr 7:100,142,565...100,148,832
Ensembl chr 7:100,142,544...100,151,227 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO RGD PMID:26451003 RGD:15036791 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
G Xdh xanthine dehydrogenase treatment ISO RGD PMID:24768926 RGD:13209011 NCBI chr17:74,190,890...74,257,369
Ensembl chr17:74,190,890...74,257,191 		JBrowse link
Lung Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2-associated X protein treatment
ameliorates		 ISO
IEP		 RGD PMID:23953793 PMID:34238924 RGD:10054119, RGD:153350155 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 treatment ISO RGD PMID:23953793 RGD:10054119 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Casp3 caspase 3 treatment ISO RGD PMID:23953793 RGD:10054119 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Col1a1 collagen, type I, alpha 1 IEP mRNA:increased expression:lung (mouse) RGD PMID:34238924 RGD:153350155 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868 		JBrowse link
G Col3a1 collagen, type III, alpha 1 IEP mRNA:increased expression:lung (mouse) RGD PMID:34238924 RGD:153350155 NCBI chr 1:45,350,698...45,388,866
Ensembl chr 1:45,350,698...45,388,866 		JBrowse link
G Crebbp CREB binding protein ameliorates IMP RGD PMID:34238924 RGD:153350155 NCBI chr16:3,899,198...4,031,864
Ensembl chr16:3,899,192...4,031,861 		JBrowse link
G Egr1 early growth response 1 treatment ISO RGD PMID:22878149 PMID:23232597 RGD:10395282, RGD:10395299 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037 		JBrowse link
G Elane elastase, neutrophil expressed treatment ISO RGD PMID:17888675 RGD:10450582 NCBI chr10:79,722,146...79,724,050
Ensembl chr10:79,722,081...79,724,049 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO mRNA:increased expression:lung (rat) RGD PMID:35600952 RGD:155663563 NCBI chr 7:129,764,181...129,868,538
Ensembl chr 7:129,764,181...132,725,079 		JBrowse link
G Hmgb1 high mobility group box 1 ISO protein:increased expression:lung RGD PMID:22115333 RGD:10402095 NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299 		JBrowse link
G Hmox1 heme oxygenase 1 ISO protein:increased expression:lung RGD PMID:21227458 RGD:10755577 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment ISO RGD PMID:22503847 RGD:7240537 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113 		JBrowse link
G Il1b interleukin 1 beta ameliorates ISO
IEP		 protein:increased expression:lung (rat) RGD PMID:23142117 PMID:34238924 PMID:23122581 RGD:7183185, RGD:153350155, RGD:7204125 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il4 interleukin 4 treatment ISO RGD PMID:24365768 RGD:10402797 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Il6 interleukin 6 ameliorates IEP RGD PMID:34238924 RGD:153350155 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog ameliorates IEP RGD PMID:34238924 RGD:153350155 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO protein:increased activity:lung RGD PMID:18694576 RGD:5129703 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770 		JBrowse link
G Myc myelocytomatosis oncogene treatment ISO RGD PMID:22503847 RGD:7240537 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell ISO
IEP		 mRNA:increased expression:lung (mouse) RGD PMID:20815765 PMID:25382268 RGD:4892012, RGD:11533932 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 treatment ISO RGD PMID:21781312 RGD:6771212 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Pecam1 platelet/endothelial cell adhesion molecule 1 ISO protein:increased expression:alveolar macrophage (rat) RGD PMID:21781312 PMID:16449942 RGD:6771212, RGD:11541083 NCBI chr11:106,545,039...106,606,107
Ensembl chr11:106,545,043...106,641,454 		JBrowse link
G Proc protein C treatment ISO RGD PMID:19782612 RGD:11100035 NCBI chr18:32,256,179...32,272,623
Ensembl chr18:32,256,179...32,272,623 		JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 treatment ISO RGD PMID:11606484 RGD:11080966 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122 		JBrowse link
G Tlr4 toll-like receptor 4 treatment ISO RGD PMID:22115333 RGD:10402095 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
G Tnf tumor necrosis factor ameliorates ISO
IEP		 RGD PMID:17294835 PMID:34238924 RGD:4143397, RGD:153350155 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Zfp36 zinc finger protein 36 exacerbates IMP RGD PMID:34238924 RGD:153350155 NCBI chr 7:28,076,208...28,078,680
Ensembl chr 7:28,076,209...28,079,678 		JBrowse link
Myocardial Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 IAGP RGD PMID:18316485 RGD:2301903 NCBI chr 7:45,753,952...45,829,441
Ensembl chr 7:45,753,947...45,829,457 		JBrowse link
G Ada adenosine deaminase ISO protein:increased expression RGD PMID:16641873 RGD:1624305 NCBI chr 2:163,565,703...163,592,154
Ensembl chr 2:163,568,504...163,592,159 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: therapeutic CTD PMID:16155579 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778 		JBrowse link
G Adrb1 adrenergic receptor, beta 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:10900253 PMID:17201736 RGD:5129149 NCBI chr19:56,710,549...56,713,582
Ensembl chr19:56,710,631...56,721,545 		JBrowse link
G Adrb2 adrenergic receptor, beta 2 ISO RGD PMID:16269402 RGD:1598746 NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030 		JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO protein:increased expression:heart (rat) RGD PMID:16505177 RGD:1625342 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910 		JBrowse link
G Agl amylo-1,6-glucosidase, 4-alpha-glucanotransferase ISO RGD PMID:9281456 RGD:1598779 NCBI chr 3:116,533,648...116,601,815
Ensembl chr 3:116,533,648...116,601,815 		JBrowse link
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:2535056 PMID:19166939 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a ISO protein:increased expression:myocardium RGD PMID:21078800 RGD:5129194 NCBI chr13:30,520,339...30,566,850
Ensembl chr13:30,520,424...30,566,850 		JBrowse link
G Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 ISO
IMP		 protein:decreased expression:mitochondrion: RGD PMID:23685150 PMID:23685150 RGD:10053560, RGD:10053560 NCBI chr  X:47,563,821...47,602,440
Ensembl chr  X:47,563,821...47,602,440 		JBrowse link
G Akt1 thymoma viral proto-oncogene 1 ISO protein:increased phosphorylation:heart left ventricle RGD PMID:20217242 RGD:5509104 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318 		JBrowse link
G Akt2 thymoma viral proto-oncogene 2 ISO RGD PMID:16418318 RGD:2313347 NCBI chr 7:27,290,977...27,340,251
Ensembl chr 7:27,290,977...27,340,251 		JBrowse link
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:9572063 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial ISO RGD PMID:23468836 RGD:7241598 NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO RGD PMID:20011686 RGD:2317527 NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139 		JBrowse link
G Angpt2 angiopoietin 2 ISO mRNA, protein:increased expression:myocardium (rat) RGD PMID:12737621 RGD:1601505 NCBI chr 8:18,740,279...18,791,578
Ensembl chr 8:18,740,279...18,791,578 		JBrowse link
G Ank1 ankyrin 1, erythroid ISO RGD PMID:9378703 RGD:1599110 NCBI chr 8:23,464,852...23,640,517
Ensembl chr 8:23,464,860...23,640,513 		JBrowse link
G Ank2 ankyrin 2, brain ISO RGD PMID:9378703 RGD:1599110 NCBI chr 3:126,715,256...127,293,996
Ensembl chr 3:126,715,261...127,292,999 		JBrowse link
G Ankrd1 ankyrin repeat domain 1 (cardiac muscle) ISO protein:decreased expression:myocardium RGD PMID:19299913 RGD:5133278 NCBI chr19:36,089,365...36,097,244
Ensembl chr19:36,089,361...36,097,499 		JBrowse link
G Anxa1 annexin A1 treatment ISO
IMP		 protein:increased expression:heart, leukocyte RGD PMID:11641252 PMID:22924634 PMID:22924634 RGD:2306910, RGD:7421655, RGD:7421655 NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308 		JBrowse link
G Apex1 apurinic/apyrimidinic endonuclease 1 ISO protein:altered localization:cytoplasm RGD PMID:17602955 RGD:2315672 NCBI chr14:51,162,406...51,164,645
Ensembl chr14:51,162,425...51,164,596 		JBrowse link
G Arrb2 arrestin, beta 2 ISO RGD PMID:29016703 RGD:13506827 NCBI chr11:70,323,051...70,331,654
Ensembl chr11:70,323,461...70,331,654 		JBrowse link
G Atf3 activating transcription factor 3 ISO RGD PMID:11485922 RGD:7327201 NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236 		JBrowse link
G Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide ISO CTD Direct Evidence: therapeutic CTD PMID:29702141 NCBI chr 3:101,483,535...101,512,023
Ensembl chr 3:101,483,535...101,512,000 		JBrowse link
G Atp2a1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 ISO RGD PMID:17630344 RGD:13782075 NCBI chr 7:126,045,032...126,062,245
Ensembl chr 7:126,045,030...126,062,280 		JBrowse link
G Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:10734148 PMID:28637456 RGD:13782080 NCBI chr 5:122,591,576...122,640,288
Ensembl chr 5:122,591,576...122,640,288 		JBrowse link
G Atp5f1d ATP synthase F1 subunit delta treatment ISO protein:decreased expression:myocardium (rat) RGD PMID:26109848 PMID:25305180 RGD:13792666, RGD:13792676 NCBI chr10:79,974,451...79,981,662
Ensembl chr10:79,974,466...79,981,652 		JBrowse link
G Bad BCL2-associated agonist of cell death treatment ISO protein:increased expression, decreased serine phosphorylation:heart RGD PMID:15339931 PMID:23364609 RGD:2292700, RGD:10053674 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267 		JBrowse link
G Bax BCL2-associated X protein treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20026869 PMID:21223820 PMID:31583047 PMID:25547710 RGD:10054103, RGD:155230831, RGD:13782178 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 treatment ISO RGD PMID:16289365 PMID:31583047 PMID:20821058 PMID:23364609 RGD:1599484, RGD:155230831, RGD:11561911, RGD:10053674 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Bcl2l1 BCL2-like 1 treatment ISO RGD PMID:12668130 RGD:11035287 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648 		JBrowse link
G Becn1 beclin 1, autophagy related treatment ISO
IMP		 RGD PMID:20821058 PMID:20812860 RGD:11561911, RGD:11561944 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112 		JBrowse link
G Bid BH3 interacting domain death agonist ISO protein:increased cleavage:heart: RGD PMID:19940077 PMID:11934844 RGD:2317561, RGD:13782263 NCBI chr 6:120,870,080...120,894,074
Ensembl chr 6:120,868,891...120,893,814 		JBrowse link
G Blk B lymphoid kinase ISO mRNA:increased expression:left ventricle (rat) RGD PMID:17562528 RGD:1642307 NCBI chr14:63,610,286...63,654,636
Ensembl chr14:63,610,285...63,654,486 		JBrowse link
G Bnip3 BCL2/adenovirus E1B interacting protein 3 treatment ISO protein:decreased expression:myocardium (human) RGD PMID:16645637 PMID:28661226 RGD:11561983, RGD:155260328 NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248 		JBrowse link
G Brd4 bromodomain containing 4 IEP mRNA,protein:increased expression:heart RGD PMID:33982231 RGD:155883171 NCBI chr17:32,415,246...32,503,717
Ensembl chr17:32,415,248...32,503,696 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 ISO mRNA:increased expression:heart RGD PMID:12909328 RGD:2289075 NCBI chr 1:134,002,603...134,006,893
Ensembl chr 1:134,002,908...134,006,858 		JBrowse link
G C3 complement component 3 ISO protein:increased expression:myocardium RGD PMID:11560858 RGD:1582136 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G Casp1 caspase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14998631 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290 		JBrowse link
G Casp12 caspase 12 treatment ISO protein:increased activity:myocardium
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:14998631 PMID:19406177 PMID:25547710 RGD:2311458, RGD:13782178 NCBI chr 9:5,345,419...5,373,034
Ensembl chr 9:5,345,430...5,373,032 		JBrowse link
G Casp3 caspase 3 ameliorates
treatment		 ISO
IEP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:14998631 PMID:18470603 PMID:30259997 PMID:29538428 RGD:2293314, RGD:329337366, RGD:13782276 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp7 caspase 7 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:14998631 PMID:29538428 RGD:13782276 NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776 		JBrowse link
G Casp8 caspase 8 ISO CTD Direct Evidence: marker/mechanism
protein:increased activity:cardiomyocyte 		CTD
RGD		 PMID:14998631 PMID:11934844 RGD:13782263 NCBI chr 1:58,834,398...58,886,662
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Casp9 caspase 9 ameliorates
treatment		 ISO
IEP		 CTD Direct Evidence: marker/mechanism
protein:increased activity:cardiomyocyte,endothelial cell		 CTD
RGD		 PMID:14998631 PMID:30259997 PMID:29538428 PMID:11934844 RGD:329337366, RGD:13782276, RGD:13782263 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287 		JBrowse link
G Casr calcium-sensing receptor ISO protein:increased expression:ventricular myocardium (rat) RGD PMID:21766206 RGD:7205698 NCBI chr16:36,310,947...36,382,605
Ensembl chr16:36,314,058...36,382,503 		JBrowse link
G Cast calpastatin ISO RGD PMID:12482022 RGD:5683872 NCBI chr13:74,840,485...74,956,993
Ensembl chr13:74,840,487...74,956,929 		JBrowse link
G Cat catalase ISO CTD Direct Evidence: therapeutic CTD
RGD		 PMID:21600015 PMID:11510883 RGD:1581149 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Cbl Casitas B-lineage lymphoma severity IMP RGD PMID:24583314 RGD:11251947 NCBI chr 9:44,054,273...44,145,556
Ensembl chr 9:44,054,273...44,145,346 		JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 ISO mRNA:increased expression:heart (rat)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:12087064 PMID:10908159 RGD:8549625 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Ccr2 chemokine (C-C motif) receptor 2 ISO protein:decreased expression:monocyte: RGD PMID:15786508 RGD:4892017 NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594 		JBrowse link
G Ccr5 chemokine (C-C motif) receptor 5 treatment ISO protein:decreased expression:blood, monocyte (human) RGD PMID:15786508 PMID:23456481 RGD:4892017, RGD:8552227 NCBI chr 9:123,921,557...123,934,153
Ensembl chr 9:123,921,580...123,947,736 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator treatment ISO RGD PMID:18466417 RGD:11341714 NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043 		JBrowse link
G Cnr1 cannabinoid receptor 1 (brain) ISO RGD PMID:18771032 RGD:2316217 NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831 		JBrowse link
G Cnr2 cannabinoid receptor 2 (macrophage) ISO RGD PMID:17950273 RGD:2316224 NCBI chr 4:135,622,500...135,647,530
Ensembl chr 4:135,622,705...135,647,518 		JBrowse link
G Cobll1 Cobl-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34355838 NCBI chr 2:64,918,683...65,069,742
Ensembl chr 2:64,918,683...65,069,747 		JBrowse link
G Crebbp CREB binding protein treatment ISO RGD PMID:24338162 RGD:153352322 NCBI chr16:3,899,198...4,031,864
Ensembl chr16:3,899,192...4,031,861 		JBrowse link
G Crp C-reactive protein, pentraxin-related ISO protein:increased expression:serum RGD PMID:21122204 RGD:5128547 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598 		JBrowse link
G Cx3cr1 chemokine (C-X3-C motif) receptor 1 ISO protein:decreased expression:blood, monocyte RGD PMID:15786508 RGD:4892017 NCBI chr 9:119,877,749...119,897,362
Ensembl chr 9:119,730,682...119,898,945 		JBrowse link
G Cxcl1 chemokine (C-X-C motif) ligand 1 ISO RGD PMID:11342480 RGD:5135269 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974 		JBrowse link
G Cxcl2 chemokine (C-X-C motif) ligand 2 ISO RGD PMID:11342480 RGD:5135269 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797 		JBrowse link
G Cxcl5 chemokine (C-X-C motif) ligand 5 ISO RGD PMID:11342480 RGD:5135269 NCBI chr 5:90,907,157...90,909,484
Ensembl chr 5:90,907,219...90,909,483 		JBrowse link
G Cybb cyt