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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Pancreatic Neoplasms
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Accession:DOID:9003100 term browser browse the term
Synonyms:exact_synonym: Pancreas Neoplasms;   pancreas neoplasm;   pancreatic neoplasm
 narrow_synonym: Borderline Exocrine Pancreatic Neoplasm
 xref: EFO:0003860;   EFO:1000133;   NCI:C34035


show annotations for term's descendants           Sort by:
Adult Pancreatic Cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl-hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12203118 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037 		JBrowse link
duodenal gastrinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Men1 multiple endocrine neoplasia 1 ISO associated with Neuroendocrine Tumors; DNA:loss of heterozygosity: : RGD PMID:17135306 RGD:2317341 NCBI chr19:6,385,009...6,390,924
Ensembl chr19:6,385,009...6,390,921 		JBrowse link
Familial Pancreatic Carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 4930550C14Rik RIKEN cDNA 4930550C14 gene ISO ClinVar Annotator: match by term: Familial pancreatic carcinoma ClinVar PMID:28492532 NCBI chr 9:53,313,814...53,345,726
Ensembl chr 9:53,313,625...53,345,702 		JBrowse link
G Apoa4 apolipoprotein A-IV ISO mRNA:increased expression:pancreas, carcinoma (human) RGD PMID:16815451 RGD:5685662 NCBI chr 9:46,152,142...46,154,756
Ensembl chr 9:46,151,994...46,154,757 		JBrowse link
G Atm ataxia telangiectasia mutated ISO ClinVar Annotator: match by term: Familial pancreatic carcinoma ClinVar PMID:8755918 PMID:9443866 PMID:9463314 PMID:9887333 PMID:10330348 More... NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G Bard1 BRCA1 associated RING domain 1 ISO ClinVar Annotator: match by term: Familial pancreatic carcinoma ClinVar PMID:25085752 PMID:25741868 PMID:26315354 PMID:26467025 PMID:26787654 More... NCBI chr 1:71,066,694...71,142,300
Ensembl chr 1:71,066,657...71,142,305 		JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A ISO ClinVar Annotator: match by term: Familial pancreatic carcinoma ClinVar PMID:7640518 PMID:7647780 PMID:7987387 PMID:8668202 PMID:9823374 More... NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890 		JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog ISO ClinVar Annotator: match by term: Familial pancreatic carcinoma ClinVar PMID:1875403 PMID:2547513 PMID:3627975 PMID:7773929 PMID:8439212 More... NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965 		JBrowse link
G Smad4 SMAD family member 4 ISO ClinVar Annotator: match by term: Familial pancreatic carcinoma ClinVar PMID:25741868 PMID:26467025 PMID:26900293 PMID:27611364 PMID:28283864 More... NCBI chr18:73,767,861...73,836,862
Ensembl chr18:73,772,080...73,836,851 		JBrowse link
G Trp53 transformation related protein 53 ISO ClinVar Annotator: match by term: Familial pancreatic carcinoma ClinVar PMID:1565143 PMID:1565144 PMID:1631137 PMID:1683921 PMID:1978757 More... NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
gastrinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Igf1r insulin-like growth factor I receptor ISO mRNA and protein: increased expression::poor prognosis for high expression RGD PMID:15867218 RGD:7242847 NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416 		JBrowse link
G Men1 multiple endocrine neoplasia 1 ISO DNA:mutations: :
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:17961653 PMID:15944766 RGD:2317354 NCBI chr19:6,385,009...6,390,924
Ensembl chr19:6,385,009...6,390,921 		JBrowse link
G Met met proto-oncogene severity ISO associated with Zollinger-Ellison Syndrome; mRNA:increased expression:tumor (human) RGD PMID:12114431 RGD:2317605 NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase ISO DNA:hypomethylation:promoter (human) RGD PMID:17278096 RGD:2317340 NCBI chr 7:136,496,315...136,732,001
Ensembl chr 7:136,496,343...136,731,995 		JBrowse link
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 ISO mRNA:decreased expression:pancreatic islet RGD PMID:8421107 PMID:12114701 RGD:2324977, RGD:2324976 NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508 		JBrowse link
Gastro-Enteropancreatic Neuroendocrine Tumor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ataxia telangiectasia mutated disease_progression ISO associated with Neoplasm Metastasis;mRNA, protein: decreased expression:gastrointestinal system, multiple (human) RGD PMID:22485171 RGD:150340716 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G Atrx ATRX, chromatin remodeler severity ISO RGD PMID:26026117 RGD:127285385 NCBI chr  X:104,841,221...104,972,978
Ensembl chr  X:104,841,221...104,973,009 		JBrowse link
G Cd53 CD53 antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 3:106,666,177...106,697,465
Ensembl chr 3:106,667,237...106,697,465 		JBrowse link
G Cd86 CD86 antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443 		JBrowse link
G Ciita class II transactivator ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr16:10,297,877...10,348,928
Ensembl chr16:10,297,923...10,346,282 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 severity ISO protein:increased expression:colon (human) RGD PMID:26259237 RGD:11530617 NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030 		JBrowse link
G Daxx Fas death domain-associated protein severity ISO RGD PMID:26026117 RGD:127285385 NCBI chr17:34,128,379...34,134,564
Ensembl chr17:34,128,388...34,134,564 		JBrowse link
G Eomes eomesodermin ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 9:118,307,259...118,315,176
Ensembl chr 9:118,307,280...118,315,200 		JBrowse link
G Gata3 GATA binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 2:9,861,889...9,894,845
Ensembl chr 2:9,861,889...9,894,845 		JBrowse link
G Gfi1 growth factor independent 1 transcription repressor ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 5:107,864,521...107,873,671
Ensembl chr 5:107,864,523...107,873,902 		JBrowse link
G Ikzf1 IKAROS family zinc finger 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr11:11,634,970...11,722,930
Ensembl chr11:11,634,980...11,722,926 		JBrowse link
G Ikzf3 IKAROS family zinc finger 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr11:98,355,436...98,437,157
Ensembl chr11:98,355,728...98,436,857 		JBrowse link
G Il10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il2rb interleukin 2 receptor, beta chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr15:78,363,456...78,396,569
Ensembl chr15:78,363,456...78,379,471 		JBrowse link
G Notch2 notch 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 3:97,920,854...98,057,683
Ensembl chr 3:97,920,843...98,057,677 		JBrowse link
G Pou2f2 POU domain, class 2, transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 7:24,790,111...24,879,292
Ensembl chr 7:24,786,769...24,879,151 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446 		JBrowse link
G Runx3 runt related transcription factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 4:134,847,956...134,905,301
Ensembl chr 4:134,847,963...134,905,301 		JBrowse link
Glucagonoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btc betacellulin, epidermal growth factor family member ISO protein:increased expression:pancreas RGD PMID:10724350 RGD:2326087 NCBI chr 5:91,505,120...91,550,853
Ensembl chr 5:91,505,120...91,550,853 		JBrowse link
G Men1 multiple endocrine neoplasia 1 IMP
ISO		 DNA:deletion:exon
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:17961653 PMID:20138042 RGD:2317288 NCBI chr19:6,385,009...6,390,924
Ensembl chr19:6,385,009...6,390,921 		JBrowse link
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 ISO mRNA:decreased expression:pancreatic islet RGD PMID:12114701 PMID:8421107 RGD:2324976, RGD:2324977 NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508 		JBrowse link
G Sstr4 somatostatin receptor 4 ISO RGD PMID:8132773 RGD:2324994 NCBI chr 2:148,237,297...148,238,684
Ensembl chr 2:148,237,264...148,238,687 		JBrowse link
insulinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin ISO protein:increased expression:pancreas, plasma RGD PMID:11331218 RGD:2325319 NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027 		JBrowse link
G Btc betacellulin, epidermal growth factor family member ISO protein:increased expression:pancreas RGD PMID:10724350 RGD:2326087 NCBI chr 5:91,505,120...91,550,853
Ensembl chr 5:91,505,120...91,550,853 		JBrowse link
G Cd40 CD40 antigen IMP RGD PMID:17982058 RGD:5491180 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868 		JBrowse link
G Cux1 cut-like homeobox 1 disease_progression
exacerbates		 IEP
ISO		 mRNA:increased expression:pancreas (mouse)
protein:increased expression:pancreas (human)		 RGD PMID:25248790 PMID:25248790 RGD:152985543, RGD:152985543 NCBI chr 5:136,276,989...136,596,429
Ensembl chr 5:136,276,989...136,596,344 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 ISO protein:increased expression:pancreas RGD PMID:19013212 RGD:2317608 NCBI chr 6:117,145,496...117,158,329
Ensembl chr 6:117,145,496...117,158,328 		JBrowse link
G Ins2 insulin II ISO protein:altered expression:blood
protein:altered localization:pancreas		 RGD PMID:8175958 PMID:2565624 RGD:2317266, RGD:2317268 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118 		JBrowse link
G Men1 multiple endocrine neoplasia 1 disease_progression IMP
ISO		 DNA:deletions:exons
CTD Direct Evidence: marker/mechanism
DNA:deletion:exon		 CTD
RGD		 PMID:17961653 PMID:19208834 PMID:12941803 PMID:20138042 RGD:2317310, RGD:2317292, RGD:2317288 NCBI chr19:6,385,009...6,390,924
Ensembl chr19:6,385,009...6,390,921 		JBrowse link
G Ncam1 neural cell adhesion molecule 1 ISO protein:increased expression:pancreas RGD PMID:8972754 RGD:2326080 NCBI chr 9:49,413,434...49,710,909
Ensembl chr 9:49,413,436...49,710,225 		JBrowse link
G Rps15 ribosomal protein S15 ISO RGD PMID:3019805 RGD:61740 NCBI chr10:80,128,265...80,129,948
Ensembl chr10:80,128,287...80,129,948 		JBrowse link
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 ISO protein:increased expression:pancreatic B cell
mRNA:decreased expression:pancreatic islet		 RGD PMID:12114701 PMID:8421107 RGD:2324976, RGD:2324977 NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508 		JBrowse link
G Tgfa transforming growth factor alpha ISO protein:increased expression:pancreas RGD PMID:8712689 RGD:2317472 NCBI chr 6:86,172,020...86,252,726
Ensembl chr 6:86,172,205...86,252,701 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO mRNA, protein:decreased expression:pancreatic islet RGD PMID:18058603 RGD:2325017 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
Islet Cell Adenomatosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mafa MAF bZIP transcription factor A ISO ClinVar Annotator: match by term: Islet cell adenomatosis OMIM
ClinVar		 PMID:25741868 PMID:29339498 PMID:35406570 NCBI chr15:75,617,350...75,620,170
Ensembl chr15:75,617,339...75,620,077 		JBrowse link
islet cell tumor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atrx ATRX, chromatin remodeler disease_progression ISO protein:decreased expression:pancreas: RGD PMID:24148618 RGD:9586032 NCBI chr  X:104,841,221...104,972,978
Ensembl chr  X:104,841,221...104,973,009 		JBrowse link
G Cdk4 cyclin dependent kinase 4 ISO protein:increased expression:pancreas, islet of Langerhans (human) RGD PMID:22761470 RGD:13452384 NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789 		JBrowse link
G Daxx Fas death domain-associated protein disease_progression ISO RGD PMID:21252315 RGD:9587819 NCBI chr17:34,128,379...34,134,564
Ensembl chr17:34,128,388...34,134,564 		JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 ISO protein:increased expression:insulinoma (rat) RGD PMID:7925129 RGD:2308920 NCBI chr13:75,237,407...75,282,980
Ensembl chr13:75,237,945...75,282,980 		JBrowse link
Islet Cell Tumor Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fntb farnesyltransferase, CAAX box, beta ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar NCBI chr12:76,884,014...76,968,188
Ensembl chr12:76,812,363...76,968,186 		JBrowse link
G Max Max protein ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:21685915 PMID:22452945 PMID:23666964 PMID:25741868 PMID:26070438 More... NCBI chr12:76,984,045...77,009,123
Ensembl chr12:76,984,043...77,008,975 		JBrowse link
G Mpz myelin protein zero ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:12807974 PMID:17468193 PMID:19454582 PMID:23342407 PMID:24033266 More... NCBI chr 1:170,978,282...170,988,699
Ensembl chr 1:170,978,280...170,988,699 		JBrowse link
G Nf1 neurofibromin 1 ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:1568247 PMID:8264648 PMID:8499944 PMID:8499945 PMID:8669813 More... NCBI chr11:79,223,541...79,472,435
Ensembl chr11:79,230,519...79,472,438 		JBrowse link
G Ret ret proto-oncogene ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:2008030 PMID:2660074 PMID:2904651 PMID:3078962 PMID:7536460 More... NCBI chr 6:118,128,709...118,174,705
Ensembl chr 6:118,128,706...118,174,679 		JBrowse link
G Sdhaf2 succinate dehydrogenase complex assembly factor 2 ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:28492532 NCBI chr19:10,477,876...10,502,573
Ensembl chr19:10,477,898...10,503,506 		JBrowse link
G Sdhb succinate dehydrogenase complex, subunit B, iron sulfur (Ip) ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:490809 PMID:2308387 PMID:9509062 PMID:9536098 PMID:11404820 More... NCBI chr 4:140,688,582...140,706,509
Ensembl chr 4:140,688,514...140,706,504 		JBrowse link
G Sdhc succinate dehydrogenase complex, subunit C, integral membrane protein ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:12807974 PMID:17468193 PMID:19454582 PMID:22517554 PMID:22703879 More... NCBI chr 1:170,956,726...170,978,209
Ensembl chr 1:170,954,734...170,978,172 		JBrowse link
G Sdhd succinate dehydrogenase complex, subunit D, integral membrane protein ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:1945482 PMID:8981955 PMID:9536098 PMID:9683583 PMID:10323245 More... NCBI chr 9:50,507,640...50,515,149
Ensembl chr 9:50,507,657...50,515,112 		JBrowse link
G Tmem127 transmembrane protein 127 ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:9536098 PMID:16266984 PMID:17576681 PMID:20154675 PMID:20923864 More... NCBI chr 2:127,089,868...127,103,028
Ensembl chr 2:127,089,828...127,103,027 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor ISO ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:7563486 PMID:7987306 PMID:8707293 PMID:8772572 PMID:8956040 More... NCBI chr 6:113,600,955...113,608,595
Ensembl chr 6:113,600,920...113,608,594 		JBrowse link
Melanoma-Pancreatic Cancer Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn2a cyclin dependent kinase inhibitor 2A ISO ClinVar Annotator: match by term: Melanoma-pancreatic cancer syndrome
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD		 PMID:2319082 PMID:2813514 PMID:5001868 PMID:7566978 PMID:7632931 More... NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890 		JBrowse link
non-functioning pancreatic endocrine tumor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid1a AT-rich interaction domain 1A exacerbates ISO protein:decreased expression:endocrine pancreas (human) RGD PMID:32282764 RGD:126790640 NCBI chr 4:133,406,319...133,484,682
Ensembl chr 4:133,406,319...133,484,080 		JBrowse link
G Cdk4 cyclin dependent kinase 4 ISO associated with multiple endocrine neoplasia type 1;mRNA:increased expression:islet of Langerhans (human) RGD PMID:29149451 RGD:13781946 NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789 		JBrowse link
G Cdk6 cyclin dependent kinase 6 ISO associated with multiple endocrine neoplasia type 1;mRNA:increased expression:islet of Langerhans (human) RGD PMID:29149451 RGD:13781946 NCBI chr 5:3,391,004...3,581,008
Ensembl chr 5:3,391,485...3,581,008 		JBrowse link
pancreatic acinar cell adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Braf Braf transforming gene ISO DNA:missense mutation, gene fusions:multiple (human) RGD PMID:25266736 RGD:13462041 NCBI chr 6:39,580,171...39,702,592
Ensembl chr 6:39,580,171...39,702,397 		JBrowse link
G Src Rous sarcoma oncogene disease_progression ISO RGD PMID:8569183 RGD:150523792 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782 		JBrowse link
pancreatic adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrb1 adhesion G protein-coupled receptor B1 ISO mRNA:decreased expression:pancreas RGD PMID:11875720 RGD:13831350 NCBI chr15:74,388,045...74,461,314
Ensembl chr15:74,388,044...74,461,314 		JBrowse link
G Akt3 thymoma viral proto-oncogene 3 severity ISO mRNA:increased expression:pancreas (human) RGD PMID:27919956 RGD:13451128 NCBI chr 1:176,847,642...177,091,688
Ensembl chr 1:176,847,639...177,085,769 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 exacerbates ISO mRNA:increased expression:pancreas (human) RGD PMID:31964418 RGD:153344516 NCBI chr 9:7,818,227...7,837,123
Ensembl chr 9:7,818,228...7,837,065 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 disease_progression ISO mRNA:increased expression:pancreas (human) RGD PMID:31964418 RGD:153344516 NCBI chr 9:7,848,698...7,873,199
Ensembl chr 9:7,848,700...7,873,187 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 exacerbates ISO mRNA:increased expression:pancreas (human) RGD PMID:31964418 RGD:153344516 NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569 		JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 exacerbates ISO mRNA:increased expression:pancreas (human) RGD PMID:31964418 RGD:153344516 NCBI chr 2:180,570,402...180,575,803
Ensembl chr 2:180,570,816...180,575,803 		JBrowse link
G Cbr4 carbonyl reductase 4 ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:9536098 PMID:17576681 PMID:25741868 PMID:28166811 PMID:28492532 NCBI chr 8:61,940,768...61,956,534
Ensembl chr 8:61,940,768...61,959,728 		JBrowse link
G Ccnd1 cyclin D1 severity ISO protein:increased expression:pancreas (human) RGD PMID:25053516 RGD:13462053 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
G Cdk4 cyclin dependent kinase 4 treatment ISO human cells in a mouse model RGD PMID:22509328 RGD:13792559 NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789 		JBrowse link
G Cdk6 cyclin dependent kinase 6 treatment ISO human cells in a mouse model RGD PMID:25050737 RGD:13782144 NCBI chr 5:3,391,004...3,581,008
Ensembl chr 5:3,391,485...3,581,008 		JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A ISO DNA:missense mutations:cds:p.V126D, p.A148T (human) RGD PMID:16397522 RGD:8552283 NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ISO RGD PMID:21448932 RGD:11352272 NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030 		JBrowse link
G E2f1 E2F transcription factor 1 treatment ISO Human cells in a mouse model RGD PMID:28797284 RGD:13838736 NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812 		JBrowse link
G Gstt1 glutathione S-transferase, theta 1 ISO RGD PMID:11854392 RGD:14700985 NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418 		JBrowse link
G Hrg histidine-rich glycoprotein disease_progression ISO RGD PMID:21713765 RGD:11041886 NCBI chr16:22,769,822...22,780,409
Ensembl chr16:22,769,822...22,780,406 		JBrowse link
G Jak1 Janus kinase 1 treatment ISO human cell line in a mouse model RGD PMID:29328487 RGD:13838743 NCBI chr 4:101,009,171...101,122,493
Ensembl chr 4:101,009,564...101,122,479 		JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 treatment
severity		 ISO human tissue in a mouse model
protein:increased expression:pancreas (human)		 RGD PMID:28849200 PMID:19513748 RGD:13838804, RGD:13838840 NCBI chr 9:64,093,066...64,160,887
Ensembl chr 9:64,093,052...64,160,913 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 severity ISO mRNA:increased expression:pancreas (human) RGD PMID:27919956 RGD:13451128 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mapk10 mitogen-activated protein kinase 10 severity ISO DNA:SNP:intron: (rs2589506) (human) RGD PMID: RGD:13838853 NCBI chr 5:103,056,413...103,359,200
Ensembl chr 5:103,055,814...103,359,200 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 exacerbates ISO protein:increased phosphorylation:pancreas (human) RGD PMID:24395444 RGD:150340683 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 ISO RGD PMID:22517435 RGD:14348976 NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248 		JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 severity ISO mRNA:increased expression:pancreas (human) RGD PMID:27919956 RGD:13451128 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308 		JBrowse link
G Palld palladin, cytoskeletal associated protein ISO ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:9536098 PMID:10454945 PMID:11474289 PMID:17194196 PMID:17415588 More... NCBI chr 8:61,964,465...62,355,741
Ensembl chr 8:61,964,467...62,355,724 		JBrowse link
G Plat plasminogen activator, tissue ISO mRNA:increased expression:pancreas (human) RGD PMID:16733850 RGD:11541045 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860 		JBrowse link
G Rac1 Rac family small GTPase 1 treatment ISO human cells in a mouse model RGD PMID:21037555 RGD:14392805 NCBI chr 5:143,491,236...143,513,786
Ensembl chr 5:143,489,389...143,513,791 		JBrowse link
G Raf1 v-raf-leukemia viral oncogene 1 treatment ISO human cells in a mouse model RGD PMID:15014358 RGD:14392893 NCBI chr 6:115,595,530...115,653,596
Ensembl chr 6:115,595,028...115,653,596 		JBrowse link
G Ralb v-ral simian leukemia viral oncogene B treatment ISO human cells in a mouse model RGD PMID:17174914 RGD:14394417 NCBI chr 1:119,398,035...119,432,512
Ensembl chr 1:119,398,035...119,432,524 		JBrowse link
G Ralbp1 ralA binding protein 1 treatment ISO human cells in a mouse model RGD PMID:22509328 RGD:13792559 NCBI chr17:66,155,410...66,192,750
Ensembl chr17:66,155,413...66,192,793 		JBrowse link
G Smad7 SMAD family member 7 severity ISO human cell and construct in a mouse model RGD PMID:10498890 RGD:14394510 NCBI chr18:75,500,436...75,529,006
Ensembl chr18:75,500,600...75,529,006 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 ameliorates ISO protein:increased expression:pancreas (human) RGD PMID:24658320 RGD:155630608 NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024 		JBrowse link
G Vegfc vascular endothelial growth factor C exacerbates ISO protein:increased expression:pancreas (human) RGD PMID:22082308 RGD:155630643 NCBI chr 8:54,530,567...54,639,489
Ensembl chr 8:54,530,641...54,640,131 		JBrowse link
pancreatic adenosquamous carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb2 transforming growth factor, beta 2 ameliorates ISO human cells in a mouse model RGD PMID:21366804 RGD:155630611 NCBI chr 1:186,354,984...186,441,504
Ensembl chr 1:186,354,989...186,438,186 		JBrowse link
pancreatic cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A4gnt alpha-1,4-N-acetylglucosaminyltransferase ISO mRNA:increased expression:blood, mononuclear cell RGD PMID:16441422 RGD:2325199 NCBI chr 9:99,473,233...99,504,420
Ensembl chr 9:99,494,555...99,504,420 		JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 ISO mRNA, protein:increased expression:pancreas RGD PMID:19020751 RGD:2317509 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179 		JBrowse link
G Abcc3 ATP-binding cassette, sub-family C member 3 severity ISO mRNA:increased expression:pancreas RGD PMID:15688370 RGD:2325200 NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823 		JBrowse link
G Abcc5 ATP-binding cassette, sub-family C member 5 ISO mRNA:increased expression:pancreas RGD PMID:15688370 RGD:2325200 NCBI chr16:20,150,053...20,245,178
Ensembl chr16:20,150,053...20,245,144 		JBrowse link
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19648918 PMID:26098869 PMID:20103627 RGD:2317511 NCBI chr 2:26,732,508...26,754,973
Ensembl chr 2:26,732,515...26,754,991 		JBrowse link
G Ace angiotensin I converting enzyme IMP RGD PMID:19880966 RGD:2325208 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790 		JBrowse link
G Acvr1 activin A receptor, type 1 ISO RGD PMID:9714055 RGD:2317217 NCBI chr 2:58,336,450...58,456,840
Ensembl chr 2:58,278,656...58,457,169 		JBrowse link
G Acvr1b activin A receptor, type 1B ISO mRNA:increased expression:pancreas
CTD Direct Evidence: marker/mechanism		 CTD
OMIM
RGD		 PMID:9714055 PMID:11248065 RGD:2317217, RGD:1598735 NCBI chr15:101,071,953...101,111,565
Ensembl chr15:101,071,948...101,111,565 		JBrowse link
G Acvr2a activin receptor IIA ISO RGD PMID:9714055 RGD:2317217 NCBI chr 2:48,704,121...48,793,276
Ensembl chr 2:48,704,121...48,793,281 		JBrowse link
G Adam15 ADAM metallopeptidase domain 15 ISO mRNA:increased expression:pancreas, epithelial cell RGD PMID:17465204 RGD:2325247 NCBI chr 3:89,246,947...89,257,589
Ensembl chr 3:89,245,849...89,257,303 		JBrowse link
G Adam9 ADAM metallopeptidase domain 9 ISO mRNA:increased expression:pancreas, epithelial cell RGD PMID:17465204 RGD:2325247 NCBI chr 8:25,439,627...25,507,138
Ensembl chr 8:25,439,627...25,506,943 		JBrowse link
G Adgre5 adhesion G protein-coupled receptor E5 ISO protein:increased expression:pancreas RGD PMID:12428789 RGD:2317573 NCBI chr 8:84,449,874...84,467,812
Ensembl chr 8:84,449,880...84,467,955 		JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) ISO DNA:polymorphism: :p.R272Q (human) RGD PMID:19068087 RGD:2325313 NCBI chr 3:137,983,346...137,996,459
Ensembl chr 3:137,966,752...137,996,459 		JBrowse link
G Adm adrenomedullin disease_progression ISO RGD PMID:16841081 PMID:17363587 RGD:2325318, RGD:2325317 NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027 		JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO protein:decreased expression:serum RGD PMID:20398646 RGD:2325643 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 ISO mRNA:increased expression:pancreas RGD PMID:11916627 RGD:2325641 NCBI chr  X:21,350,863...21,355,072
Ensembl chr  X:21,350,783...21,355,403 		JBrowse link
G Ahr aryl-hydrocarbon receptor ISO mRNA:increased expression:pancreas
CTD Direct Evidence: marker/mechanism|therapeutic		 CTD
RGD		 PMID:12203118 PMID:25826687 PMID:12203118 RGD:2325664 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037 		JBrowse link
G Akt1 thymoma viral proto-oncogene 1 severity
treatment		 ISO protein:increased phosphorylation:pancreas (human)
human cells in a mouse model		 RGD PMID:20697673 PMID:11595724 RGD:13450953, RGD:13452388 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318 		JBrowse link
G Akt2 thymoma viral proto-oncogene 2 ISO RGD PMID:16847462 PMID:19506583 RGD:2290476, RGD:5490965 NCBI chr 7:27,290,977...27,340,251
Ensembl chr 7:27,290,977...27,340,251 		JBrowse link
G Alb albumin disease_progression ISO RGD PMID:18154768 PMID:20508721 RGD:2325678, RGD:2325675 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 ISO protein:decreased expression:pancreas RGD PMID:19216797 RGD:2325688 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial susceptibility ISO DNA:polymorphism: :p.E504K (human)
DNA:polymorphism (human)		 RGD PMID:19068087 PMID:15714130 RGD:2325313, RGD:2325694 NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887 		JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr11:69,047,898...69,060,617
Ensembl chr11:69,047,815...69,060,618 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:pancreas		 CTD
RGD		 PMID:30258081 PMID:12481414 PMID:12163367 RGD:2317523, RGD:2317524 NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139 		JBrowse link
G Ang angiogenin, ribonuclease, RNase A family, 5 disease_progression ISO mRNA, protein:increased expression:pancreas, serum RGD PMID:8665497 RGD:2325716 NCBI chr14:51,328,607...51,339,462
Ensembl chr14:51,328,607...51,339,466 		JBrowse link
G Anxa1 annexin A1 ISO protein:increased expression:pancreas RGD PMID:19173988 PMID:17974280 RGD:2325722, RGD:2325723 NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308 		JBrowse link
G Anxa10 annexin A10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28369074 NCBI chr 8:62,510,076...62,576,227
Ensembl chr 8:62,510,076...62,576,184 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 ISO mRNA:increased expression:pancreas RGD PMID:17224646 RGD:2325739 NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632 		JBrowse link
G Apc APC, WNT signaling pathway regulator ISO
IAGP		 DNA:deletions (human)
ClinVar Annotator: match by term: Cancer of the pancreas
DNA:mutation, loss of heterozygosity		 ClinVar
RGD		 PMID:1316610 PMID:8381579 PMID:9101302 PMID:9824584 PMID:11852337 More... RGD:2317208, RGD:2317207 NCBI chr18:34,353,350...34,455,243
Ensembl chr18:34,353,977...34,455,605 		JBrowse link
G Apoa1 apolipoprotein A-I ISO protein:decreased expression:serum
protein:increased expression:pancreas		 RGD PMID:17312459 PMID:17332923 RGD:2325758, RGD:2325757 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764 		JBrowse link
G Apoe apolipoprotein E ISO protein:increased expression:pancreas (human) RGD PMID:16215274 RGD:2317552 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Arid1a AT-rich interaction domain 1A ISO RGD PMID:23355908 RGD:8694154 NCBI chr 4:133,406,319...133,484,682
Ensembl chr 4:133,406,319...133,484,080 		JBrowse link
G Arid1b AT-rich interaction domain 1B ISO RGD PMID:23355908 RGD:8694154 NCBI chr17:5,044,481...5,397,931
Ensembl chr17:5,044,607...5,397,931 		JBrowse link
G Arpc1a actin related protein 2/3 complex, subunit 1A ISO DNA:amplification (human) RGD PMID:19145645 RGD:2317557 NCBI chr 5:145,020,679...145,045,566
Ensembl chr 5:145,020,640...145,045,571 		JBrowse link
G Artn artemin disease_progression ISO mRNA:increased expression:pancreas RGD PMID:19304517 PMID:20395845 RGD:2325817, RGD:2325815 NCBI chr 4:117,783,105...117,787,993
Ensembl chr 4:117,783,359...117,786,960 		JBrowse link
G Atm ataxia telangiectasia mutated susceptibility ISO DNA:SNP:intron:rs664677 (human)
ClinVar Annotator: match by term: Pancreatic cancer
CTD Direct Evidence: marker/mechanism
DNA:SNP:exon:rs1801516(human)
DNA:SNP: :60G>A(human)		 ClinVar
CTD
RGD		 PMID:8698354 PMID:8845835 PMID:9497252 PMID:9536098 PMID:9792409 More... RGD:2317367, RGD:2317363, RGD:2317234 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G Atr ataxia telangiectasia and Rad3 related ISO DNA:SNP: :340C>T (human) RGD PMID:18381943 RGD:2317234 NCBI chr 9:95,739,655...95,834,813
Ensembl chr 9:95,739,650...95,833,834 		JBrowse link
G Atrx ATRX, chromatin remodeler ISO CTD Direct Evidence: marker/mechanism CTD PMID:21252315 NCBI chr  X:104,841,221...104,972,978
Ensembl chr  X:104,841,221...104,973,009 		JBrowse link
G Axl AXL receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26206560 NCBI chr 7:25,455,925...25,488,502
Ensembl chr 7:25,456,698...25,488,130 		JBrowse link
G B3galt5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 ISO mRNA:increased expression:pancreas RGD PMID:14555842 RGD:2317558 NCBI chr16:96,037,001...96,121,059
Ensembl chr16:96,037,001...96,121,059 		JBrowse link
G Bad BCL2-associated agonist of cell death treatment ISO human cells in a mouse model RGD PMID:23523869 RGD:13451129 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267 		JBrowse link
G Bag3 BCL2-associated athanogene 3 ISO mRNA:increased expression:pancreas RGD PMID:11513873 RGD:2325843 NCBI chr 7:128,125,307...128,148,705
Ensembl chr 7:128,125,340...128,148,705 		JBrowse link
G Bag4 BCL2-associated athanogene 4 ISO mRNA:increased expression:pancreas RGD PMID:10799310 RGD:2325852 NCBI chr 8:26,254,566...26,275,237
Ensembl chr 8:26,254,566...26,275,315 		JBrowse link
G Bap1 Brca1 associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231345 NCBI chr14:30,973,358...30,981,887
Ensembl chr14:30,973,407...30,981,901 		JBrowse link
G Bcar1 breast cancer anti-estrogen resistance 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr 8:112,437,106...112,470,481
Ensembl chr 8:112,437,106...112,470,441 		JBrowse link
G Bcl2l1 BCL2-like 1 severity ISO human gene in a mouse model
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16904634 PMID:17941720 RGD:11353794 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648 		JBrowse link
G Bid BH3 interacting domain death agonist ISO RGD PMID:15943879 RGD:2317560 NCBI chr 6:120,870,080...120,894,074
Ensembl chr 6:120,868,891...120,893,814 		JBrowse link
G Boc BOC cell adhesion associated, oncogene regulated ISO RGD PMID:18772397 RGD:5490966 NCBI chr16:44,305,408...44,379,233
Ensembl chr16:44,305,412...44,379,260 		JBrowse link
G Braf Braf transforming gene disease_progression IMP
ISO		 human gene in a mouse model RGD PMID:18490924 PMID:22628411 PMID:22871572 RGD:13451537, RGD:13462040, RGD:13461863 NCBI chr 6:39,580,171...39,702,592
Ensembl chr 6:39,580,171...39,702,397 		JBrowse link
G Brca1 breast cancer 1, early onset ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 4 | ClinVar Annotator: match by term: Pancreatic cancer | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 4
ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 4 | ClinVar Annotator: match by term: Pancreatic cancer | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 2 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 4
ClinVar Annotator: match by term: Cancer of the pancreas | ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 4 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 2 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 4
ClinVar Annotator: match by term: Cancer of the pancreas | ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 4 | ClinVar Annotator: match by term: Pancreatic cancer 3 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 4
ClinVar Annotator: match by term: Cancer of the pancreas | ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 4 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 1 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 4
ClinVar Annotator: match by term: Cancer of the pancreas | ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 4 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 4		 CTD
OMIM
ClinVar		 PMID:1157798 PMID:2173504 PMID:2316185 PMID:2504116 PMID:2618727 More... NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781 		JBrowse link
G Brca2 breast cancer 2, early onset susceptibility ISO DNA:mutations: :
ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 2 | ClinVar Annotator: match by term: Pancreatic cancer | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 2
ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 2 | ClinVar Annotator: match by term: Pancreatic cancer | ClinVar Annotator: match by term: Pancreatic cancer 3 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 2 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 3 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 4
ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 2 | ClinVar Annotator: match by term: Pancreatic cancer | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 1 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 2
ClinVar Annotator: match by term: Cancer of the pancreas | ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 2 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 2 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 4
ClinVar Annotator: match by term: Cancer of the pancreas | ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 2 | ClinVar Annotator: match by term: Pancreatic cancer 3 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 2
CTD Direct Evidence: marker/mechanism		 ClinVar
OMIM
CTD
RGD		 PMID:186727 PMID:251866 PMID:278235 PMID:1772447 PMID:2200631 More... RGD:9068467 NCBI chr 5:150,445,759...150,493,612
Ensembl chr 5:150,446,095...150,493,794 		JBrowse link
G Bsg basigin ISO CTD Direct Evidence: marker/mechanism CTD PMID:36574092 NCBI chr10:79,540,192...79,547,813
Ensembl chr10:79,540,325...79,547,803 		JBrowse link
G Bub1b BUB1B, mitotic checkpoint serine/threonine kinase ISO protein:altered localization:pancreas RGD PMID:17242465 RGD:2326105 NCBI chr 2:118,428,684...118,472,073
Ensembl chr 2:118,428,692...118,472,072 		JBrowse link
G Cab39 calcium binding protein 39 disease_progression ISO RGD PMID:28197410 RGD:14398834 NCBI chr 1:85,707,796...85,779,298
Ensembl chr 1:85,721,162...85,779,297 		JBrowse link
G Cacybp calcyclin binding protein disease_progression ISO mRNA, protein:increased expression:pancreas RGD PMID:18765951 RGD:2326146 NCBI chr 1:160,029,171...160,040,391
Ensembl chr 1:160,029,937...160,040,445 		JBrowse link
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 disease_progression ISO mRNA, protein:increased expression:pancreas RGD PMID:19188911 RGD:2326238 NCBI chr 4:122,752,841...122,779,869
Ensembl chr 4:122,752,840...122,779,849 		JBrowse link
G Capn10 calpain 10 susceptibility ISO DNA:SNP:intron:rs3792267 (human) RGD PMID:20178008 RGD:4107073 NCBI chr 1:92,862,130...92,875,670
Ensembl chr 1:92,862,098...92,875,663 		JBrowse link
G Casp8 caspase 8 susceptibility ISO DNA:deletion, insertion:promoter (human)
DNA:SNP: :rs1045485 (human)		 RGD PMID:18483392 PMID:19843670 RGD:2315744, RGD:2317230 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Casp9 caspase 9 susceptibility
treatment		 ISO DNA:snp:promoter:g.-1263A>G (human) RGD PMID:20357690 PMID:19209030 RGD:13451540, RGD:13462046 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287 		JBrowse link
G Cat catalase disease_progression ISO protein:decreased expression:pancreas RGD PMID:12499913 RGD:2317410 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Cbr4 carbonyl reductase 4 ISO ClinVar Annotator: match by term: PALLD-related condition | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 1 ClinVar PMID:25741868 PMID:28492532 NCBI chr 8:61,940,768...61,956,534
Ensembl chr 8:61,940,768...61,959,728 		JBrowse link
G Cckar cholecystokinin A receptor ISO mRNA:increased expression:pancreas RGD PMID:10457335 PMID:8222074 RGD:4110817, RGD:4110822 NCBI chr 5:53,855,827...53,865,046
Ensembl chr 5:53,855,118...53,865,047 		JBrowse link
G Cckbr cholecystokinin B receptor disease_progression
susceptibility		 ISO mRNA:increased expression:pancreas RGD PMID:8222074 PMID:8302799 PMID:1458479 PMID:15688412 RGD:4110822, RGD:4110823, RGD:4110821, RGD:4110829 NCBI chr 7:105,075,201...105,085,546
Ensembl chr 7:105,074,938...105,120,105 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:30603057 PMID:10225458 RGD:7483623 NCBI chr 1:83,094,487...83,096,888
Ensembl chr 1:83,094,487...83,096,888 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IMP RGD PMID:19155524 RGD:2317567 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344 		JBrowse link
G Ccnd1 cyclin D1 disease_progression
treatment		 ISO
IEP		 human cells in a mouse model
mRNA, protein:increased expression:pancreas (mouse)		 RGD PMID:22722256 PMID:11159909 PMID:17541034 RGD:13451541, RGD:13452385, RGD:13462059 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
G Ccng1 cyclin G1 treatment ISO human cells in mouse model RGD PMID:11177556 RGD:151361109 NCBI chr11:40,639,379...40,646,044
Ensembl chr11:40,639,379...40,646,138 		JBrowse link
G Ccr4 C-C motif chemokine receptor 4 ISO protein:increased expression:pancreas RGD PMID:12761880 RGD:2317610 NCBI chr 9:114,319,384...114,334,544
Ensembl chr 9:114,319,384...114,333,984 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 IMP RGD PMID:19155524 RGD:2317567 NCBI chr 9:123,921,557...123,934,153
Ensembl chr 9:123,921,580...123,947,736 		JBrowse link
G Cd24a CD24a antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:28369074 NCBI chr10:43,454,433...43,460,261
Ensembl chr10:43,454,280...43,460,261 		JBrowse link
G Cd44 CD44 antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:17446842 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010 		JBrowse link
G Cdc42 cell division cycle 42 severity ISO mRNA, protein:increased expression:pancreas (human) RGD PMID:28181096 RGD:13452244 NCBI chr 4:137,047,011...137,085,007
Ensembl chr 4:137,047,007...137,085,031 		JBrowse link
G Cdh1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18223216 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878 		JBrowse link
G Cdk4 cyclin dependent kinase 4 susceptibility
disease_progression		 ISO
IMP
IEP		 protein:increased expression:islet of Langerhans (human)
protein:increased expression:islet of Langerhans, nucleus (rat)
protein:increased expression:pancreas (mouse)		 RGD PMID:22761470 PMID:24531709 PMID:22477723 PMID:11159909 RGD:13452384, RGD:13452387, RGD:13452386, RGD:13452385 NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789 		JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A ISO DNA:mutations:exon
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:10627132 PMID:26098869 PMID:18772397 RGD:5490966 NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:20876774 NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043 		JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator no_association
onset		 ISO RGD PMID:17072959 PMID:16227367 RGD:2317157, RGD:2317156 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767 		JBrowse link
G Chek1 checkpoint kinase 1 disease_progression ISO DNA:SNP: :35G>A (human) RGD PMID:18381943 RGD:2317234 NCBI chr 9:36,619,935...36,637,897
Ensembl chr 9:36,619,778...36,638,361 		JBrowse link
G Cldn4 claudin 4 ISO RGD PMID:19555390 PMID:19793693 RGD:2317583, RGD:2317580 NCBI chr 5:134,973,977...134,975,788
Ensembl chr 5:134,973,973...134,975,788 		JBrowse link
G Clptm1 cleft lip and palate associated transmembrane protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr 7:19,365,505...19,398,955
Ensembl chr 7:19,365,496...19,398,958 		JBrowse link
G Cnr1 cannabinoid receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16818650 NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831 		JBrowse link
G Cnr2 cannabinoid receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16818650 NCBI chr 4:135,622,500...135,647,530
Ensembl chr 4:135,622,705...135,647,518 		JBrowse link
G Ctnnb1 catenin beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18223216 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573 		JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18307536 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926 		JBrowse link
G Cycs cytochrome c, somatic ISO RGD PMID:11920648 RGD:2317614 NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 susceptibility ISO DNA:transition:5' utr:-34T>C rs743572 (human) RGD PMID:19642097 RGD:2317618 NCBI chr19:46,655,604...46,661,439
Ensembl chr19:46,655,604...46,661,611 		JBrowse link
G Daxx Fas death domain-associated protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21252315 NCBI chr17:34,128,379...34,134,564
Ensembl chr17:34,128,388...34,134,564 		JBrowse link
G Ddr1 discoidin domain receptor family, member 1 treatment IAGP RGD PMID:31310125 RGD:151347425 NCBI chr17:35,992,459...36,015,633
Ensembl chr17:35,992,459...36,015,513 		JBrowse link
G Dpyd dihydropyrimidine dehydrogenase disease_progression ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:pancreas		 CTD
RGD		 PMID:17443278 PMID:19020767 PMID:18309485 PMID:20072795 RGD:2317630, RGD:2317629 NCBI chr 3:118,355,758...119,226,573
Ensembl chr 3:118,355,778...119,226,573 		JBrowse link
G Dyrk1a dual-specificity tyrosine phosphorylation regulated kinase 1a ISO CTD Direct Evidence: marker/mechanism CTD PMID:31838052 NCBI chr16:94,370,770...94,496,378
Ensembl chr16:94,370,869...94,496,376 		JBrowse link
G E2f1 E2F transcription factor 1 treatment ISO RGD PMID:28344092 RGD:13838737 NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812 		JBrowse link
G Efemp1 epidermal growth factor-containing fibulin-like extracellular matrix protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208748 NCBI chr11:28,803,154...28,876,743
Ensembl chr11:28,803,204...28,876,743 		JBrowse link
G Egf epidermal growth factor disease_progression ISO protein:increased expression:pancreas RGD PMID:1347773 PMID:19506583 RGD:2317650, RGD:5490965 NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965 		JBrowse link
G Egfr epidermal growth factor receptor ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:27720938 PMID:17452677 PMID:19506583 RGD:5131631, RGD:5490965 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158 		JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 ISO protein:increased expression:serum (human) RGD PMID:15796914 RGD:10045549 NCBI chr11:119,179,189...119,190,869
Ensembl chr11:119,179,189...119,190,915 		JBrowse link
G Epcam epithelial cell adhesion molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:17446842 NCBI chr17:87,943,407...87,958,555
Ensembl chr17:87,943,407...87,958,557 		JBrowse link
G Epha3 Eph receptor A3 ISO RGD PMID:14670182 RGD:2317720 NCBI chr16:63,363,895...63,684,538
Ensembl chr16:63,363,897...63,684,538 		JBrowse link
G Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 susceptibility ISO DNA:snp:3' utr:c.*197G>T (rs3212986) (human) RGD PMID:27050953 RGD:13207426 NCBI chr 7:19,079,016...19,090,449
Ensembl chr 7:19,078,703...19,090,449 		JBrowse link
G Ercc2 excision repair cross-complementing rodent repair deficiency, complementation group 2 treatment ISO DNA,protein:SNPs:exons:rs1799793,rs1052559(human)
pancreatic adenocarcinoma;DNA:SNPs: :rs1799793,rs1052555(human)		 RGD PMID:16458430 PMID:21404106 PMID:18544627 RGD:2317228, RGD:11252206, RGD:2317223 NCBI chr 7:19,115,942...19,129,619
Ensembl chr 7:19,115,935...19,129,619 		JBrowse link
G Ercc4 excision repair cross-complementing rodent repair deficiency, complementation group 4 ISO pancreatic adenocarcinoma;DNA:SNP: :rs1800067(human) RGD PMID:18544627 RGD:2317223 NCBI chr16:12,927,600...12,969,873
Ensembl chr16:12,927,548...12,968,481 		JBrowse link
G Etaa1 Ewing tumor-associated antigen 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr11:17,888,753...17,903,875
Ensembl chr11:17,888,756...17,903,875 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO protein:increased expression:pancreas RGD PMID:22222375 RGD:9588324 NCBI chr 6:47,507,208...47,613,843
Ensembl chr 6:47,507,073...47,572,275 		JBrowse link
G Fanca Fanconi anemia, complementation group A ISO DNA,Protein:polymorphisms:exons:c.377C>G, c.661A>G (human) RGD PMID:15591268 RGD:2317735 NCBI chr 8:123,993,033...124,045,390
Ensembl chr 8:123,995,039...124,045,315 		JBrowse link
G Fancc Fanconi anemia, complementation group C ISO DNA:nonsense mutation (human) RGD PMID:15695377 PMID:16243825 RGD:2317239, RGD:2317238 NCBI chr13:63,452,519...63,645,126
Ensembl chr13:63,432,857...63,645,092 		JBrowse link
G Fancg Fanconi anemia, complementation group G ISO RGD PMID:16243825 RGD:2317238 NCBI chr 4:43,002,337...43,010,565
Ensembl chr 4:43,002,343...43,010,506 		JBrowse link
G Fasl Fas ligand severity
resistance		 ISO DNA:polymorphism:promoter:-844>>T (human) RGD PMID:11115536 PMID:12370548 PMID:18483392 RGD:2317745, RGD:2317744, RGD:2315744 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064 		JBrowse link
G Fgf13 fibroblast growth factor 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19917848 NCBI chr  X:58,107,499...58,630,932
Ensembl chr  X:58,107,505...58,613,431 		JBrowse link
G Fgf2 fibroblast growth factor 2 severity ISO mRNA:increased expression:pancreas
protein:increased expression:bile		 RGD PMID:12670449 PMID:11562741 PMID:11478488 PMID:9293890 RGD:2317759, RGD:2317760, RGD:2317765, RGD:2317762 NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257 		JBrowse link
G Flt3l FMS-like tyrosine kinase 3 ligand ISO RGD PMID:16528542 RGD:11049499 NCBI chr 7:44,780,607...44,785,914
Ensembl chr 7:44,779,212...44,785,856 		JBrowse link
G Foxp1 forkhead box P1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25485836 NCBI chr 6:98,902,303...99,510,587
Ensembl chr 6:98,902,299...99,499,682 		JBrowse link
G Fscn1 fascin actin-bundling protein 1 severity ISO protein:increased expression:pancreas RGD PMID:17696949 RGD:2317785 NCBI chr 5:142,946,110...142,958,944
Ensembl chr 5:142,946,098...142,958,940 		JBrowse link
G Fxyd3 FXYD domain-containing ion transport regulator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16003754 NCBI chr 7:30,769,960...30,776,122
Ensembl chr 7:30,767,597...30,776,129 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha ISO CTD Direct Evidence: therapeutic CTD PMID:19003803 NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441 		JBrowse link
G Gdnf glial cell line derived neurotrophic factor severity ISO RGD PMID:18652760 RGD:2324925 NCBI chr15:7,839,529...7,867,061
Ensembl chr15:7,840,327...7,867,056 		JBrowse link
G Gli1 GLI-Kruppel family member GLI1 ISO RGD PMID:21186299 PMID:18772397 RGD:5491005, RGD:5490966 NCBI chr10:127,165,751...127,177,448
Ensembl chr10:127,165,751...127,177,843 		JBrowse link
G Gli3 GLI-Kruppel family member GLI3 ISO RGD PMID:18772397 RGD:5490966 NCBI chr13:15,638,308...15,904,611
Ensembl chr13:15,637,820...15,904,611 		JBrowse link
G Gnas GNAS complex locus ISO RGD PMID:12771991 RGD:2317256 NCBI chr 2:174,126,113...174,188,537
Ensembl chr 2:174,126,113...174,188,537 		JBrowse link
G Golm1 golgi membrane protein 1 ISO RGD PMID:37338014 RGD:401827117 NCBI chr13:59,782,810...59,823,598
Ensembl chr13:59,782,440...59,823,625 		JBrowse link
G Gstp1 glutathione S-transferase, pi 1 susceptibility ISO DNA:SNP:cds:p.I105V (rs1695) (human) RGD PMID:19786118 PMID:19536452 RGD:2317804, RGD:2317805 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985 		JBrowse link
G Hgf hepatocyte growth factor ISO protein:increased expression:serum RGD PMID:20017454 RGD:2317895 NCBI chr 5:16,758,493...16,827,448
Ensembl chr 5:16,758,493...16,825,150 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:16628086 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304 		JBrowse link
G Hs3st2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 ISO DNA:hypermethylation:promoter (human) RGD PMID:12527896 RGD:2317633 NCBI chr 7:120,990,785...121,196,555
Ensembl chr 7:120,991,082...121,100,993 		JBrowse link
G Hspb1 heat shock protein 1 disease_progression ISO RGD PMID:21833720 RGD:10402768 NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417 		JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO mRNA, protein:increased expression:pancreas RGD PMID:11815996 RGD:2325165 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113 		JBrowse link
G Ifna1 interferon alpha 1 ISO CTD Direct Evidence: therapeutic CTD PMID:17198089 PMID:17961653 NCBI chr 4:88,768,324...88,768,893
Ensembl chr 4:88,768,324...88,768,893 		JBrowse link
G Ifna2 interferon alpha 2 ISO CTD Direct Evidence: therapeutic CTD PMID:12738744 NCBI chr 4:88,601,444...88,602,016
Ensembl chr 4:88,601,118...88,602,149 		JBrowse link
G Ifng interferon gamma ISO protein:increased expression:plasma RGD PMID:19152246 RGD:2317258 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Igf1 insulin-like growth factor 1 susceptibility ISO DNA:polymorphism (human) RGD PMID:19064563 RGD:2306689 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904 		JBrowse link
G Igf1r insulin-like growth factor I receptor ISO RGD PMID:14559833 PMID:19885860 PMID:19732452 RGD:2317651, RGD:2317640, RGD:2317642 NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416 		JBrowse link
G Il10 interleukin 10 disease_progression
susceptibility		 ISO protein:increased expression:serum
DNA:polymorphism: :-1082G>A (human)		 RGD PMID:17235586 PMID:30304975 PMID:30610790 PMID:19250218 RGD:2317655, RGD:14975257, RGD:14975253, RGD:2317653 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il13 interleukin 13 disease_progression ISO protein:increased expression:pancreas RGD PMID:12808442 PMID:18758789 RGD:2317670, RGD:2317669 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529 		JBrowse link
G Il13ra2 interleukin 13 receptor, alpha 2 treatment ISO RGD PMID:11748276 RGD:8549514 NCBI chr  X:146,166,474...146,214,982
Ensembl chr  X:146,166,472...146,212,188 		JBrowse link
G Il1a interleukin 1 alpha ISO RGD PMID:7787209 RGD:2311069 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892 		JBrowse link
G Il1b interleukin 1 beta susceptibility ISO DNA:polymorphisms:promoter:-511C>T, -31T>C (human)
protein:increased expression:serum (human)		 RGD PMID:19251436 PMID:7787209 RGD:2317215, RGD:2311069 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il2 interleukin 2 treatment ISO RGD PMID:9080118 RGD:8663440 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108 		JBrowse link
G Il24 interleukin 24 ISO CTD Direct Evidence: therapeutic CTD PMID:15580305 NCBI chr 1:130,809,801...130,815,153
Ensembl chr 1:130,809,811...130,815,191 		JBrowse link
G Il3 interleukin 3 ISO protein:increased expression:serum RGD PMID:15843207 RGD:2317663 NCBI chr11:54,155,911...54,158,105
Ensembl chr11:54,156,129...54,158,103 		JBrowse link
G Il4 interleukin 4 disease_progression ISO
IDA		 protein:increased expression:blood RGD PMID:19957810 PMID:12097255 PMID:10404069 RGD:2317261, RGD:2317265, RGD:2317267 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Il4ra interleukin 4 receptor, alpha disease_progression ISO protein:increased expression:pancreas RGD PMID:18758789 RGD:2317669 NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646 		JBrowse link
G Il6 interleukin 6 disease_progression ISO RGD PMID:30610790 PMID:30304975 RGD:14975253, RGD:14975257 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Ilk integrin linked kinase ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr 7:105,385,797...105,392,132
Ensembl chr 7:105,385,799...105,392,132 		JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase, type II ISO CTD Direct Evidence: marker/mechanism CTD PMID:29415082 NCBI chr 8:82,068,895...82,865,553
Ensembl chr 8:82,069,185...82,854,543 		JBrowse link
G Ins2 insulin II susceptibility
disease_progression		 ISO
IDA		 associated with Diabetes Mellitus
DNA:Polymorphism:promoter:-23 HphI (human)
associated with Diabetes Mellitus, Non-Insulin-Depend		 RGD PMID:19375425 PMID:19152242 PMID:19628082 PMID:19572116 RGD:2317250, RGD:2317253, RGD:2317245, RGD:2317247 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118 		JBrowse link
G Itga11 integrin alpha 11 ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr 9:62,585,137...62,691,618
Ensembl chr 9:62,585,108...62,691,264 		JBrowse link
G Itga4 integrin alpha 4 ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr 2:79,084,767...79,163,458
Ensembl chr 2:79,085,770...79,163,467 		JBrowse link
G Itga9 integrin alpha 9 ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr 9:118,435,777...118,730,071
Ensembl chr 9:118,435,758...118,730,071 		JBrowse link
G Kdr kinase insert domain protein receptor ISO CTD Direct Evidence: therapeutic CTD
RGD		 PMID:12385004 PMID:19930156 RGD:5684397 NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118 		JBrowse link
G Klf5 Kruppel-like transcription factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr14:99,536,127...99,550,848
Ensembl chr14:99,536,127...99,552,472 		JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
OMIM
RGD		 PMID:14520703 PMID:19424582 PMID:21699781 PMID:24694877 PMID:25961927 More... RGD:1581761, RGD:5490966, RGD:5490965 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965 		JBrowse link
G L1cam L1 cell adhesion molecule treatment ISO RGD PMID:22095073 RGD:11570404 NCBI chr  X:72,897,384...72,924,843
Ensembl chr  X:72,897,384...72,939,711 		JBrowse link
G Ldha lactate dehydrogenase A ISO CTD Direct Evidence: marker/mechanism CTD PMID:29384525 NCBI chr 7:46,491,698...46,505,051
Ensembl chr 7:46,490,899...46,505,051 		JBrowse link
G Lig3 ligase III, DNA, ATP-dependent resistance ISO DNA:SNP:intron:rs 2074522 (human) RGD PMID:19147782 RGD:2317363 NCBI chr11:82,671,977...82,695,100
Ensembl chr11:82,671,934...82,695,100 		JBrowse link
G Lig4 ligase IV, DNA, ATP-dependent susceptibility ISO associated with Diabetes Mellitus;DNA:polymorphism: :54C>T (human) RGD PMID:19147782 RGD:2317363 NCBI chr 8:10,020,020...10,027,680
Ensembl chr 8:10,019,049...10,027,686 		JBrowse link
G Lrp2 low density lipoprotein receptor-related protein 2 ISO RGD PMID:18772397 RGD:5490966 NCBI chr 2:69,254,679...69,416,373
Ensembl chr 2:69,254,684...69,416,409 		JBrowse link
G Lum lumican disease_progression ISO DNA:SNP: :rs2268578 (human) RGD PMID:19843670 PMID:17671699 RGD:2317230, RGD:2317682 NCBI chr10:97,401,363...97,408,565
Ensembl chr10:97,400,990...97,408,565 		JBrowse link
G Ly6e lymphocyte antigen 6 family member E ISO CTD Direct Evidence: marker/mechanism CTD PMID:17446842 NCBI chr15:74,826,874...74,831,753
Ensembl chr15:74,826,900...74,831,752 		JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor no_association ISO DNA:polymorphisms: :multiple (human)
DNA:point mutations, deletions:cds:multiple (human)		 RGD PMID:17072959 PMID:9174057 RGD:2317157, RGD:2325804 NCBI chr 9:106,765,952...106,769,137
Ensembl chr 9:106,715,511...106,769,178 		JBrowse link
G Map2k4 mitogen-activated protein kinase kinase 4 ISO RGD PMID:18772397 RGD:5490966 NCBI chr11:65,579,070...65,679,185
Ensembl chr11:65,579,069...65,679,123 		JBrowse link
G Men1 multiple endocrine neoplasia 1 ISO associated with Neuroendocrine Tumors; protein:increased expression:multiple organs
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:17961653 PMID:21252315 PMID:17278096 RGD:2317340 NCBI chr19:6,385,009...6,390,924
Ensembl chr19:6,385,009...6,390,921 		JBrowse link
G Met met proto-oncogene severity ISO protein:increased expression:pancreas (rat)
mRNA:increased expression:pancreas (human)		 RGD PMID:9211490 PMID:19506583 PMID:15448002 RGD:2317613, RGD:5490965, RGD:2317235 NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979 		JBrowse link
G Mgat4a mannoside acetylglucosaminyltransferase 4, isoenzyme A ISO RGD PMID:16434023 RGD:2317701 NCBI chr 1:37,478,421...37,580,599
Ensembl chr 1:37,478,421...37,580,097 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase ISO protein:decreased expression:neuroendocrine tumor (human) RGD PMID:19118063 RGD:2317628 NCBI chr 7:136,496,315...136,732,001
Ensembl chr 7:136,496,343...136,731,995 		JBrowse link
G Mir107 microRNA 107 severity ISO RGD PMID:28720759 RGD:14975279 NCBI chr19:34,798,087...34,798,173
Ensembl chr19:34,798,087...34,798,173 		JBrowse link
G Mir1193 microRNA 1193 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29859832 NCBI chr12:109,682,105...109,682,225
Ensembl chr12:109,682,105...109,682,225 		JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 disease_progression ISO protein:increased expression:pancreas RGD PMID:20137856 PMID:20350215 RGD:2317704, RGD:2317703 NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090 		JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO mRNA:increased expression:pancreas
CTD Direct Evidence: marker/mechanism
protein:increased activity:pancreatic juice		 CTD
RGD		 PMID:30603057 PMID:7635566 PMID:11961486 RGD:2325766, RGD:2325752 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048 		JBrowse link
G Mmp9 matrix metallopeptidase 9 disease_progression ISO
IMP		 protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:pancreas		 CTD
RGD		 PMID:22952646 PMID:19629003 PMID:18030366 PMID:18445772 PMID:7635566 RGD:2325831, RGD:2325854, RGD:2325849, RGD:2325766 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770 		JBrowse link
G Mpo myeloperoxidase resistance ISO DNA:polymorphism:promoter:-463G>A (human) RGD PMID:18205184 RGD:2317406 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239 		JBrowse link
G Msln mesothelin ISO associated with Pancreatic Disease; protein:increased expression:pancreas
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:11751476 PMID:17019794 PMID:18281514 PMID:17785569 PMID:19843662 RGD:2326060, RGD:2326056, RGD:2326062, RGD:2326052 NCBI chr17:25,967,587...25,973,352
Ensembl chr17:25,967,587...25,973,352 		JBrowse link
G Mtap methylthioadenosine phosphorylase ISO DNA, protein:deletion, decreased activity:pancreas: RGD PMID:15534104 RGD:2317952 NCBI chr 4:89,055,607...89,099,327
Ensembl chr 4:89,055,359...89,099,318 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase susceptibility ISO DNA:polymorphism: :677C>T (human) RGD PMID:16737574 RGD:2317120 NCBI chr 4:148,123,534...148,144,019
Ensembl chr 4:148,123,534...148,144,008 		JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO RGD PMID:23149918 RGD:10040959 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase susceptibility
no_association		 ISO DNA:Polymorphism: :rs1805087 (human) RGD PMID:18843018 PMID:16737574 RGD:2317118, RGD:2317120 NCBI chr13:12,196,217...12,273,090
Ensembl chr13:12,197,598...12,272,999 		JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase susceptibility ISO DNA:polymorphism: :66A>G (human)
DNA:SNPs:intron, exon:rs162049, p.H595Y (rs10380) (human)		 RGD PMID:18843018 PMID:18515090 RGD:2317118, RGD:2325772 NCBI chr13:68,708,897...68,730,273
Ensembl chr13:68,708,899...68,730,268 		JBrowse link
G Muc1 mucin 1, transmembrane disease_progression ISO protein:increased expression:pancreas
protein:increased secretion:bile		 RGD PMID:14654947 PMID:18039393 PMID:18383873 PMID:19129927 PMID:19055478 More... RGD:2317984, RGD:2324639, RGD:2324637, RGD:2317987, RGD:2324622, RGD:2324635 NCBI chr 3:89,136,363...89,140,688
Ensembl chr 3:89,136,364...89,140,688 		JBrowse link
G Muc16 mucin 16 ISO protein:increased expression:serum RGD PMID:19377061 RGD:2325129 NCBI chr 9:18,406,741...18,586,117
Ensembl chr 9:18,406,751...18,585,826 		JBrowse link
G Muc4 mucin 4 disease_progression ISO mRNA:increased expression:peripheral blood mononuclear cell
protein:increased expression:pancreas
mRNA:increased expression:pancreas		 RGD PMID:16274046 PMID:17595659 PMID:20303649 PMID:11751498 PMID:17406026 RGD:2324931, RGD:2324922, RGD:2324914, RGD:2324891, RGD:2324923 NCBI chr16:32,555,089...32,602,786
Ensembl chr16:32,555,015...32,602,754 		JBrowse link
G Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric ISO protein:increased expression:pancreas
protein:increased glycosylation:serum		 RGD PMID:14654947 PMID:19377061 RGD:2317984, RGD:2325129 NCBI chr 7:141,342,695...141,372,964
Ensembl chr 7:141,342,709...141,372,968 		JBrowse link
G Muc6 mucin 6, gastric ISO protein:increased expression: : RGD PMID:10209489 RGD:2325167 NCBI chr 7:141,212,404...141,241,659
Ensembl chr 7:141,213,373...141,241,641 		JBrowse link
G Myc myelocytomatosis oncogene IMP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:25961927 PMID:22024988 RGD:7240699 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223 		JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 ISO human gene in a mouse model RGD PMID:25071868 RGD:9590074 NCBI chr10:111,308,754...111,334,011
Ensembl chr10:111,309,084...111,334,011 		JBrowse link
G Nat1 N-acetyl transferase 1 susceptibility ISO DNA:polymorphism (human)
DNA:polymorphisms,haplotype: :		 RGD PMID:18499698 PMID:18006927 PMID:18006927 RGD:2317168, RGD:2317170, RGD:2317170 NCBI chr 8:67,943,620...67,945,183
Ensembl chr 8:67,933,573...67,944,756 		JBrowse link
G Nat2 N-acetyltransferase 2 (arylamine N-acetyltransferase) susceptibility ISO DNA:polymorphism (human) RGD PMID:18027363 RGD:2317169 NCBI chr 8:67,947,527...67,955,296
Ensembl chr 8:67,947,510...67,955,236 		JBrowse link
G Ncam1 neural cell adhesion molecule 1 severity
disease_progression		 ISO RGD PMID:10374842 PMID:11249065 RGD:2326075, RGD:2326074 NCBI chr 9:49,413,434...49,710,909
Ensembl chr 9:49,413,436...49,710,225 		JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha ISO CTD Direct Evidence: therapeutic CTD PMID:15861417 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432 		JBrowse link
G Ngfr nerve growth factor receptor (TNFR superfamily, member 16) severity ISO mRNA:increased expression:tumor:associated with longer overall survival (human) RGD PMID:16704535 RGD:5508229 NCBI chr11:95,459,644...95,478,524
Ensembl chr11:95,459,644...95,478,561 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible disease_progression IMP
IDA
ISO		 protein:increased expression:pancreas RGD PMID:11196200 PMID:11687972 PMID:15165031 RGD:2325262, RGD:2325257, RGD:2325248 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Notch1 notch 1 disease_progression IMP protein:increased expression:pancreas RGD PMID:17297654 RGD:2325328 NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20660371 NCBI chr15:101,151,783...101,172,676
Ensembl chr15:101,152,150...101,172,676 		JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20101243 PMID:26098869 NCBI chr 1:136,770,300...136,888,186
Ensembl chr 1:136,770,309...136,888,186 		JBrowse link
G Nrp1 neuropilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15956974 NCBI chr 8:129,085,553...129,231,957
Ensembl chr 8:129,085,085...129,229,844 		JBrowse link
G Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 severity ISO mRNA:increased expression:tumor:associated with increased tumor aggressiveness (human) RGD PMID:16704535 RGD:5508229 NCBI chr 3:87,685,551...87,702,549
Ensembl chr 3:87,685,551...87,702,469 		JBrowse link
G Nuf2 NUF2, NDC80 kinetochore complex component treatment ISO mRNA:increased expression:pancreas RGD PMID:26045769 PMID:25370920 RGD:11058437, RGD:28867232 NCBI chr 1:169,325,503...169,359,033
Ensembl chr 1:169,325,503...169,359,033 		JBrowse link
G Ogg1 8-oxoguanine DNA-glycosylase 1 disease_progression ISO DNA:polymorphism: :rs1052133 (human)
DNA:polymorphism: :2657G>A (human)		 RGD PMID:18559563 PMID:17230526 RGD:2317130, RGD:2317132 NCBI chr 6:113,303,959...113,311,149
Ensembl chr 6:113,303,933...113,312,029 		JBrowse link
G Palb2 partner and localizer of BRCA2 susceptibility ISO DNA:nonsense mutations:exon:172_175del, 3116del, 3256C>T (human)
ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 3 | ClinVar Annotator: match by term: Pancreatic cancer | ClinVar Annotator: match by term: Pancreatic cancer 3 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 3
ClinVar Annotator: match by term: Cancer of the pancreas | ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 3 | ClinVar Annotator: match by term: Pancreatic cancer 3 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 1 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 3
ClinVar Annotator: match by term: Cancer of the pancreas | ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 3 | ClinVar Annotator: match by term: Pancreatic cancer 3 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 2 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 3
ClinVar Annotator: match by term: Cancer of the pancreas | ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 3 | ClinVar Annotator: match by term: Pancreatic cancer 3 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 3 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 4
ClinVar Annotator: match by term: Cancer of the pancreas | ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 3 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 3
ClinVar Annotator: match by term: Cancer of the pancreas | ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 3 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 1 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 3
ClinVar Annotator: match by term: Cancer of the pancreas | ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 1 | ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 3 | ClinVar Annotator: match by term: Pancreatic cancer 3
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD
RGD		 PMID:100849 PMID:9536098 PMID:16199547 PMID:17200668 PMID:17200671 More... RGD:2325776 NCBI chr 7:121,706,485...121,732,203
Ensembl chr 7:121,706,485...121,732,208 		JBrowse link
G Palld palladin, cytoskeletal associated protein susceptibility ISO
IEP		 DNA, mRNA:missense mutation, increased expression:pancreas:p.P239S (human)
ClinVar Annotator: match by term: PALLD-related condition | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 1 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 2
ClinVar Annotator: match by term: PALLD-related condition | ClinVar Annotator: match by term: Pancreatic cancer 3 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 1
ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 2 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 1
CTD Direct Evidence: marker/mechanism
protein:increased expression, alternative form:pancreas, fibroblast		 ClinVar
CTD
OMIM
RGD		 PMID:10454945 PMID:11474289 PMID:17194196 PMID:17415588 PMID:24033266 More... RGD:2325782, RGD:2325779 NCBI chr 8:61,964,465...62,355,741
Ensembl chr 8:61,964,467...62,355,724 		JBrowse link
G Pbrm1 polybromo 1 ISO RGD PMID:23355908 RGD:8694154 NCBI chr14:30,741,095...30,843,549
Ensembl chr14:30,741,095...30,843,549 		JBrowse link
G Pdgfra platelet derived growth factor receptor, alpha polypeptide ISO mRNA:increased expression:pancreas RGD PMID:7665222 PMID:14695158 RGD:2324851, RGD:2324850 NCBI chr 5:75,311,988...75,358,867
Ensembl chr 5:75,312,953...75,358,876 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19077462 PMID:25086665 PMID:26098869 NCBI chr 5:147,206,907...147,212,658
Ensembl chr 5:147,206,769...147,212,658 		JBrowse link
G Pfn1 profilin 1 ISO RGD PMID:16215274 RGD:2317552 NCBI chr11:70,542,670...70,547,625
Ensembl chr11:70,542,676...70,545,470 		JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:10467400 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453 		JBrowse link
G Polb polymerase (DNA directed), beta disease_progression ISO DNA:polymorphisms: :165A>G, 2133T>C (human) RGD PMID:17230526 RGD:2317132 NCBI chr 8:23,118,135...23,143,482
Ensembl chr 8:23,118,142...23,143,451 		JBrowse link
G Ppard peroxisome proliferator activator receptor delta disease_progression IMP
ISO		 RGD PMID:17652168 PMID:17652168 RGD:2324872, RGD:2324872 NCBI chr17:28,451,715...28,520,446
Ensembl chr17:28,451,674...28,520,448 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma susceptibility ISO CTD Direct Evidence: marker/mechanism|therapeutic
DNA:polymorphism: :p.P12A (human)		 CTD
RGD		 PMID:11034103 PMID:11741176 PMID:19152448 PMID:19436234 RGD:2317462, RGD:2317460 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360 		JBrowse link
G Ptch1 patched 1 ISO protein:increased expression:pancreas
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:19077462 PMID:19396459 RGD:2324910 NCBI chr13:63,656,142...63,721,274
Ensembl chr13:63,656,142...63,721,412 		JBrowse link
G Pten phosphatase and tensin homolog ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19917848 PMID:19506583 RGD:5490965 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 susceptibility ISO DNA:polymorphisms: :-1195A>A ,-765G>C (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :-1195A > G, -765G > C (human)
mRNA, protein:increased expression:pancreas		 CTD
RGD		 PMID:10485483 PMID:10657949 PMID:15705899 PMID:16820089 PMID:19422084 More... RGD:2317184, RGD:5135527, RGD:2317175, RGD:2317179 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Pthlh parathyroid hormone-like peptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:17625444 NCBI chr 6:147,153,607...147,165,511
Ensembl chr 6:147,153,599...147,165,681 		JBrowse link
G Rabl3 RAB, member RAS oncogene family-like 3 susceptibility ISO ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 5 | ClinVar Annotator: match by term: RABL3-related condition
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:31406347 NCBI chr16:37,360,220...37,392,747
Ensembl chr16:37,360,247...37,392,747 		JBrowse link
G Rad51 RAD51 recombinase ISO protein:increased expression:pancreas (rat) RGD PMID:20197614 RGD:9831172 NCBI chr 2:118,943,295...118,966,554
Ensembl chr 2:118,943,274...118,977,926 		JBrowse link
G Rad54l RAD54 like (S. cerevisiae) ISO DNA:SNP:exon:rs1048771 (human) RGD PMID:16540687 RGD:2317365 NCBI chr 4:115,951,458...115,980,875
Ensembl chr 4:115,951,461...115,980,887 		JBrowse link
G Rap1gap Rap1 GTPase-activating protein ISO mRNA:decreased expression:pancreas (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:22614916 PMID:16424023 RGD:9835037 NCBI chr 4:137,391,549...137,457,172
Ensembl chr 4:137,392,037...137,457,172 		JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21699781 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262 		JBrowse link
G Recql RecQ protein-like ISO DNA:SNPs:introns
DNA:SNP:3'utr:rs13035 (human)		 RGD PMID:19768149 PMID:18422747 PMID:16540687 RGD:2317369, RGD:2317370, RGD:2317365 NCBI chr 6:142,296,068...142,332,802
Ensembl chr 6:142,296,068...142,332,813 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) ISO RGD PMID:9918209 RGD:2298892 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Ret ret proto-oncogene disease_progression ISO protein:increased expression:pancreas RGD PMID:16269310 RGD:2324926 NCBI chr 6:118,128,709...118,174,705
Ensembl chr 6:118,128,706...118,174,679 		JBrowse link
G Rhbdd1 rhomboid domain containing 1 ISO CTD Direct Evidence: therapeutic CTD PMID:35442567 NCBI chr 1:82,294,178...82,423,087
Ensembl chr 1:82,294,173...82,423,087 		JBrowse link
G Rrm2 ribonucleotide reductase M2 ISO RGD PMID:19568409 RGD:2324950 NCBI chr12:24,758,253...24,764,145
Ensembl chr12:24,758,240...24,764,145 		JBrowse link
G Runx3 runt related transcription factor 3 disease_progression ISO DNA:hypermethylation, loss of heterozygosity (human) RGD PMID:18475302 RGD:2324956 NCBI chr 4:134,847,956...134,905,301
Ensembl chr 4:134,847,963...134,905,301 		JBrowse link
G Rxra retinoid X receptor alpha ISO RGD PMID:19152448 RGD:2317462 NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969 		JBrowse link
G Sel1l sel-1 suppressor of lin-12-like (C. elegans) ISO RGD PMID:14508516 RGD:2317190 NCBI chr12:91,772,817...91,815,931
Ensembl chr12:91,772,817...91,815,931 		JBrowse link
G Serpina1e serine (or cysteine) peptidase inhibitor, clade A, member 1E disease_progression ISO RGD PMID:2323846 RGD:2324960 NCBI chr12:103,913,190...103,923,156
Ensembl chr12:103,913,190...103,925,234 		JBrowse link
G Sf3b4 splicing factor 3b, subunit 4 ISO mRNA, protein:decreased expression:pancreas (human) RGD PMID:28351319 RGD:155804299 NCBI chr 3:96,079,822...96,084,880
Ensembl chr 3:96,079,648...96,084,880 		JBrowse link
G Shh sonic hedgehog ISO RGD PMID:19506583 RGD:5490965 NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254 		JBrowse link
G Sinhcaf SIN3-HDAC complex associated factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:35213078 NCBI chr 6:148,822,538...148,847,968
Ensembl chr 6:148,822,533...148,847,965 		JBrowse link
G Slc1a5 solute carrier family 1 (neutral amino acid transporter), member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35929395 NCBI chr 7:16,515,259...16,532,199
Ensembl chr 7:16,515,265...16,532,199 		JBrowse link
G Slc29a1 solute carrier family 29 (nucleoside transporters), member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18728667 NCBI chr17:45,896,126...45,910,544
Ensembl chr17:45,896,126...45,910,532 		JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 ISO mRNA:decreased expression:pancreas (human) RGD PMID:21625523 RGD:152995425 NCBI chr 7:99,307,011...99,360,547
Ensembl chr 7:99,307,011...99,360,547 		JBrowse link
G Smad2 SMAD family member 2 ISO mRNA:increased expression:pancreas (human) RGD PMID:10505717 RGD:14394490 NCBI chr18:76,369,898...76,444,819
Ensembl chr18:76,374,651...76,444,034 		JBrowse link
G Smad3 SMAD family member 3 ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276 		JBrowse link
G Smad4 SMAD family member 4 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Cancer of the pancreas
DNA:mutations:exon		 OMIM
CTD
ClinVar
RGD		 PMID:25741868 PMID:18772397 RGD:5490966 NCBI chr18:73,767,861...73,836,862
Ensembl chr18:73,772,080...73,836,851 		JBrowse link
G Smad7 SMAD family member 7 ISO mRNA:increased expression:pancreas (human) RGD PMID:10498890 RGD:14394510 NCBI chr18:75,500,436...75,529,006
Ensembl chr18:75,500,600...75,529,006 		JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 ISO RGD PMID:23355908 RGD:8694154 NCBI chr 9:21,527,377...21,615,526
Ensembl chr 9:21,527,465...21,615,526 		JBrowse link
G Smo smoothened, frizzled class receptor treatment ISO
IMP		 protein:increased expression:pancreas RGD PMID:19396459 PMID:22859707 PMID:19460966 RGD:2324910, RGD:150340554, RGD:2324978 NCBI chr 6:29,735,480...29,761,359
Ensembl chr 6:29,735,502...29,761,364 		JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 ISO RGD PMID:17726579 RGD:2302550 NCBI chr 5:144,813,305...144,902,657
Ensembl chr 5:144,813,305...144,902,657 		JBrowse link
G Sncg synuclein, gamma ISO RGD PMID:15221989 RGD:6478801 NCBI chr14:34,092,231...34,096,626
Ensembl chr14:34,092,231...34,096,746 		JBrowse link
G Snw1 SNW domain containing 1 susceptibility ISO DNA:snp:intron: T>A (human) (rs1477261) RGD PMID:20056645 RGD:11035249 NCBI chr12:87,496,680...87,519,069
Ensembl chr12:87,495,845...87,519,044 		JBrowse link
G Sod1 superoxide dismutase 1, soluble ISO protein:decreased expression:pancreas RGD PMID:12499913 RGD:2317410 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217 		JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial susceptibility
disease_progression		 ISO DNA:polymorphism:cds:p.A16V (human)
CTD Direct Evidence: marker/mechanism
protein:decreased expression:pancreas		 CTD
RGD		 PMID:11328670 PMID:17895890 PMID:18205184 PMID:12700280 PMID:12499913 RGD:2317406, RGD:1581235, RGD:2317410 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950 		JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19896093 NCBI chr18:43,861,134...43,870,302
Ensembl chr18:43,861,147...43,870,622 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:15970685 RGD:1581363 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916 		JBrowse link
G Sst somatostatin ISO CTD Direct Evidence: therapeutic CTD PMID:2868874 NCBI chr16:23,708,327...23,710,041
Ensembl chr16:23,708,323...23,709,708 		JBrowse link
G Sstr1 somatostatin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17625444 NCBI chr12:58,258,524...58,262,822
Ensembl chr12:58,258,558...58,260,673 		JBrowse link
G Sstr2 somatostatin receptor 2 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:15259086 PMID:17625444 PMID:19917848 NCBI chr11:113,510,153...113,516,854
Ensembl chr11:113,510,168...113,516,854 		JBrowse link
G Sstr3 somatostatin receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17625444 NCBI chr15:78,421,214...78,433,565
Ensembl chr15:78,421,208...78,428,885 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22348037 PMID:23845849 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
G Stk11 serine/threonine kinase 11 ISO CTD Direct Evidence: marker/mechanism OMIM
CTD		 PMID:26098869 NCBI chr10:79,951,602...79,966,513
Ensembl chr10:79,951,637...79,966,516 		JBrowse link
G Sugct succinyl-CoA glutarate-CoA transferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr13:17,032,057...17,869,380
Ensembl chr13:17,032,057...17,870,138 		JBrowse link
G Sycp1 synaptonemal complex protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14991579 NCBI chr 3:102,725,815...102,843,416
Ensembl chr 3:102,725,815...102,843,416 		JBrowse link
G Tcf7l2 transcription factor 7 like 2, T cell specific, HMG box ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr19:55,730,227...55,922,091
Ensembl chr19:55,730,252...55,922,086 		JBrowse link
G Tert telomerase reverse transcriptase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25086665 PMID:26098869 NCBI chr13:73,775,030...73,797,962
Ensembl chr13:73,775,030...73,797,962 		JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16965396 NCBI chr 6:3,962,589...3,988,977
Ensembl chr 6:3,962,595...3,988,919 		JBrowse link
G Tgfa transforming growth factor alpha ISO mRNA, protein:increased expression:pancreas RGD PMID:1401070 PMID:19506583 PMID:17785207 RGD:2317473, RGD:5490965, RGD:2317468 NCBI chr 6:86,172,020...86,252,726
Ensembl chr 6:86,172,205...86,252,701 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 disease_progression ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:serum		 CTD
RGD		 PMID:23992306 PMID:18787407 PMID:16933058 RGD:2325015, RGD:2325018 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor II disease_progression ISO DNA:deletion, frameshift mutations (human)
DNA:mutations:exon
protein:increased expresssion:pancreas
mRNA:increased expresssion:pancreas		 RGD PMID:9850059 PMID:18772397 PMID:11866987 PMID:9365135 RGD:2317501, RGD:5490966, RGD:2317499, RGD:2317502 NCBI chr 9:115,916,763...116,004,431
Ensembl chr 9:115,913,361...116,004,428 		JBrowse link
G Tgm2 transglutaminase 2, C polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:30108682 NCBI chr 2:157,958,325...157,988,312
Ensembl chr 2:157,958,322...157,988,356 		JBrowse link
G Thbs1 thrombospondin 1 disease_progression ISO DNA:hypermethylation (human) RGD PMID:10766168 PMID:20203415 PMID:16757110 RGD:2325028, RGD:2325021, RGD:2325023 NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614 		JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: therapeutic CTD PMID:16211219 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 ISO CTD Direct Evidence: therapeutic CTD PMID:11234897 NCBI chr 3:27,371,226...27,393,814
Ensembl chr 3:27,371,177...27,396,576 		JBrowse link
G Trp53 transformation related protein 53 ISO
EXP		 DNA:mutations:exon
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:23873029 PMID:26390243 PMID:18772397 RGD:5490966 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Trp53bp1 transformation related protein 53 binding protein 1 IMP RGD PMID:11585747 RGD:2325154 NCBI chr 2:121,025,316...121,126,830
Ensembl chr 2:121,023,762...121,101,888 		JBrowse link
G Trp63 transformation related protein 63 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr16:25,502,513...25,710,842
Ensembl chr16:25,502,513...25,710,852 		JBrowse link
G Tsc2 TSC complex subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19917848 NCBI chr17:24,814,788...24,851,607
Ensembl chr17:24,814,790...24,851,604 		JBrowse link
G Tymp thymidine phosphorylase ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17443278 PMID:19671868 RGD:2325156 NCBI chr15:89,255,834...89,261,282
Ensembl chr15:89,256,134...89,261,242 		JBrowse link
G Tyms thymidylate synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19020767 NCBI chr 5:30,243,544...30,279,261
Ensembl chr 5:30,263,200...30,278,615 		JBrowse link
G Uck2 uridine-cytidine kinase 2 ISO protein:increased expression:pancreatic neoplasm (human) RGD PMID:12149149 RGD:5133269 NCBI chr 1:167,050,464...167,112,657
Ensembl chr 1:167,050,452...167,112,889 		JBrowse link
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C no_association ISO DNA:polymorphisms: :multiple (human)
DNA:polymorphisms: :p.N129K, p.R131K, p.W208R (human)		 RGD PMID:17072959 PMID:12806614 RGD:2317157, RGD:2317503 NCBI chr 1:88,022,723...88,147,724
Ensembl chr 1:88,022,784...88,147,724 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO RGD PMID:17652277 RGD:2325162 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337 		JBrowse link
G Vegfb vascular endothelial growth factor B ISO CTD Direct Evidence: marker/mechanism CTD PMID:24604347 NCBI chr19:6,959,840...6,965,019
Ensembl chr19:6,959,841...6,965,019 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor ISO DNA:hypermethylation, deletion:promoter (human)
associated with Hippel-Lindau Disease;DNA:missense mutation:exon:p.R238Q (human)		 RGD PMID:19690016 PMID:9488521 RGD:2325169, RGD:2325176 NCBI chr 6:113,600,955...113,608,595
Ensembl chr 6:113,600,920...113,608,594 		JBrowse link
G Wnt9a wingless-type MMTV integration site family, member 9A ISO DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr11:59,197,675...59,224,378
Ensembl chr11:59,197,754...59,224,378 		JBrowse link
G Wt1 WT1 transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19196508 NCBI chr 2:104,956,874...105,003,959
Ensembl chr 2:104,956,874...105,003,961 		JBrowse link
G Xpc xeroderma pigmentosum, complementation group C ISO DNA:polymorphism:intron:AF076952 (human) RGD PMID:18559563 RGD:2317130 NCBI chr 6:91,466,287...91,492,870
Ensembl chr 6:91,466,287...91,492,870 		JBrowse link
G Xpo1 exportin 1 exacerbates ISO protein:increased expression:pancreas (human) RGD PMID:20003838 RGD:151665797 NCBI chr11:23,205,768...23,248,250
Ensembl chr11:23,206,055...23,248,249 		JBrowse link
G Xpo5 exportin 5 IEP mRNA:decreased expression:pancreas (mouse) RGD PMID:26516699 RGD:11041739 NCBI chr17:46,513,737...46,554,524
Ensembl chr17:46,513,708...46,554,524 		JBrowse link
G Xrcc1 X-ray repair complementing defective repair in Chinese hamster cells 1 ISO DNA:SNP:exon:rs1799782 (human) RGD PMID:16520463 RGD:2317367 NCBI chr 7:24,246,124...24,272,863
Ensembl chr 7:24,245,714...24,272,865 		JBrowse link
G Xrcc2 X-ray repair complementing defective repair in Chinese hamster cells 2 ISO DNA:SNP:exon:rs3218536 (human)
DNA:polymorphism: :p.R188H (human)		 RGD PMID:16540687 PMID:17986315 RGD:2317365, RGD:2317507 NCBI chr 5:25,894,812...25,910,795
Ensembl chr 5:25,894,810...25,910,823 		JBrowse link
G Xrcc3 X-ray repair complementing defective repair in Chinese hamster cells 3 ISO DNA:SNP:cd:rs861539 (human) RGD PMID:18559563 RGD:2317130 NCBI chr12:111,769,626...111,780,326
Ensembl chr12:111,769,626...111,780,307 		JBrowse link
G Znrf3 zinc and ring finger 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25086665 PMID:26098869 NCBI chr11:5,226,329...5,394,847
Ensembl chr11:5,226,324...5,394,847 		JBrowse link
pancreatic carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 4930550C14Rik RIKEN cDNA 4930550C14 gene ISO ClinVar Annotator: match by term: Carcinoma of pancreas | ClinVar Annotator: match by term: PANCREATIC CARCINOMA ClinVar PMID:988733 PMID:1849795 PMID:3338800 PMID:8808599 PMID:9443866 More... NCBI chr 9:53,313,814...53,345,726
Ensembl chr 9:53,313,625...53,345,702 		JBrowse link
G Acvr1b activin A receptor, type 1B ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:11248065 NCBI chr15:101,071,953...101,111,565
Ensembl chr15:101,071,948...101,111,565 		JBrowse link
G Atm ataxia telangiectasia mutated ISO ClinVar Annotator: match by term: Carcinoma of pancreas | ClinVar Annotator: match by term: PANCREATIC CARCINOMA ClinVar PMID:988733 PMID:1849795 PMID:3338800 PMID:8808599 PMID:9443866 More... NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G Brca1 breast cancer 1, early onset ISO ClinVar Annotator: match by term: Carcinoma of head of pancreas | ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:9150174 PMID:10667592 PMID:10667595 PMID:11802209 PMID:12566964 More... NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781 		JBrowse link
G Brca2 breast cancer 2, early onset ISO ClinVar Annotator: match by term: Carcinoma of pancreas | ClinVar Annotator: match by term: PANCREATIC CARCINOMA ClinVar PMID:8665505 PMID:9150150 PMID:9361038 PMID:9536098 PMID:9585613 More... NCBI chr 5:150,445,759...150,493,612
Ensembl chr 5:150,446,095...150,493,794 		JBrowse link
G Brip1 BRCA1 interacting protein C-terminal helicase 1 ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:16116423 PMID:17033622 PMID:21964575 PMID:25330149 PMID:25741868 More... NCBI chr11:85,948,957...86,092,041
Ensembl chr11:85,948,964...86,092,019 		JBrowse link
G Cbr4 carbonyl reductase 4 ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:17194196 PMID:25741868 PMID:28492532 NCBI chr 8:61,940,768...61,956,534
Ensembl chr 8:61,940,768...61,959,728 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A ISO RGD PMID:9252195 RGD:8662427 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A susceptibility ISO DNA:insertion:cds:p.R112_L113insR (human) RGD PMID:10922411 RGD:8552383 NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890 		JBrowse link
G Chd3 chromodomain helicase DNA binding protein 3 disease_progression ISO protein:increased expression:pancreas RGD PMID:21472101 RGD:9587766 NCBI chr11:69,234,099...69,260,325
Ensembl chr11:69,234,099...69,260,232 		JBrowse link
G Chek2 checkpoint kinase 2 ISO ClinVar Annotator: match by term: Carcinoma of pancreas | ClinVar Annotator: match by term: PANCREATIC CARCINOMA ClinVar PMID:9536098 PMID:10617473 PMID:11053450 PMID:11479205 PMID:11719428 More... NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011 		JBrowse link
G Ercc4 excision repair cross-complementing rodent repair deficiency, complementation group 4 ISO ClinVar Annotator: match by term: PANCREATIC CARCINOMA ClinVar PMID:8797827 PMID:9579555 PMID:20221251 PMID:21228398 PMID:21612988 More... NCBI chr16:12,927,600...12,969,873
Ensembl chr16:12,927,548...12,968,481 		JBrowse link
G Fance Fanconi anemia, complementation group E ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:11001585 PMID:17924555 PMID:21279724 PMID:25741868 PMID:26822949 More... NCBI chr17:28,532,504...28,545,548
Ensembl chr17:28,532,493...28,545,546 		JBrowse link
G Fancg Fanconi anemia, complementation group G ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar NCBI chr 4:43,002,337...43,010,565
Ensembl chr 4:43,002,343...43,010,506 		JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 severity ISO protein:increased expression:pancreas (rat) RGD PMID:21472101 RGD:9587766 NCBI chr 6:51,437,414...51,448,054
Ensembl chr 6:51,437,912...51,446,874 		JBrowse link
G Hoxb13 homeobox B13 ISO ClinVar Annotator: match by term: PANCREATIC CARCINOMA ClinVar PMID:8756292 PMID:15964834 PMID:17138648 PMID:22236224 PMID:22714738 More... NCBI chr11:96,085,142...96,087,436
Ensembl chr11:96,085,142...96,088,273 		JBrowse link
G Kdr kinase insert domain protein receptor treatment ISO RGD PMID:17414626 RGD:126848809 NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118 		JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog IAGP
ISO		 OMIM:260350
ClinVar Annotator: match by term: Carcinoma of pancreas | ClinVar Annotator: match by term: PANCREATIC CARCINOMA		 MouseDO
ClinVar		 PMID:1875403 PMID:7773929 PMID:8439212 PMID:12110640 PMID:12720172 More... NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965 		JBrowse link
G Mir155 microRNA 155 ISO miRNA:increased expression:serum RGD PMID:28660759 RGD:24922217 NCBI chr16:84,511,028...84,511,092
Ensembl chr16:84,511,028...84,511,092 		JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment IMP RGD PMID:25425965 RGD:11570510 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140 		JBrowse link
G Myc myelocytomatosis oncogene IAGP OMIM:260350 MouseDO NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223 		JBrowse link
G Nbn nibrin ISO ClinVar Annotator: match by term: PANCREATIC CARCINOMA ClinVar PMID:9590180 PMID:9590181 PMID:9620777 PMID:10398434 PMID:10799436 More... NCBI chr 4:15,955,388...15,992,589
Ensembl chr 4:15,957,925...15,992,589 		JBrowse link
G Palb2 partner and localizer of BRCA2 ISO ClinVar Annotator: match by term: PANCREATIC CARCINOMA ClinVar PMID:17200668 PMID:17200671 PMID:17200672 PMID:20122277 PMID:20412113 More... NCBI chr 7:121,706,485...121,732,203
Ensembl chr 7:121,706,485...121,732,208 		JBrowse link
G Palld palladin, cytoskeletal associated protein ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:17194196 PMID:25741868 PMID:28492532 NCBI chr 8:61,964,465...62,355,741
Ensembl chr 8:61,964,467...62,355,724 		JBrowse link
G Pold1 polymerase (DNA directed), delta 1, catalytic subunit ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar NCBI chr 7:44,182,168...44,198,239
Ensembl chr 7:44,182,170...44,198,273 		JBrowse link
G Raf1 v-raf-leukemia viral oncogene 1 ISO mRNA:increased expression:pancreas (rat) RGD PMID:2278633 RGD:14392892 NCBI chr 6:115,595,530...115,653,596
Ensembl chr 6:115,595,028...115,653,596 		JBrowse link
G Rbbp8 retinoblastoma binding protein 8, endonuclease ISO ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:9811458 PMID:28492532 NCBI chr18:11,766,333...11,876,264
Ensembl chr18:11,766,333...11,878,278 		JBrowse link
G Smad4 SMAD family member 4 ISO ClinVar Annotator: match by term: Carcinoma of pancreas | ClinVar Annotator: match by term: PANCREATIC CARCINOMA ClinVar PMID:8653691 PMID:9582123 PMID:9811934 PMID:10398437 PMID:10764709 More... NCBI chr18:73,767,861...73,836,862
Ensembl chr18:73,772,080...73,836,851 		JBrowse link
G Stk11 serine/threonine kinase 11 ISO ClinVar Annotator: match by term: Carcinoma of pancreas | ClinVar Annotator: match by term: PANCREATIC CARCINOMA ClinVar PMID:10362809 PMID:11430832 PMID:15188174 PMID:15800014 PMID:16287113 More... NCBI chr10:79,951,602...79,966,513
Ensembl chr10:79,951,637...79,966,516 		JBrowse link
G Trp53 transformation related protein 53 ISO ClinVar Annotator: match by term: Carcinoma of pancreas | ClinVar Annotator: match by term: PANCREATIC CARCINOMA ClinVar PMID:1565143 PMID:1565144 PMID:1581912 PMID:1591732 PMID:1631137 More... NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Tsc1 TSC complex subunit 1 IMP RGD PMID:25425965 RGD:11570510 NCBI chr 2:28,531,005...28,581,183
Ensembl chr 2:28,531,240...28,581,179 		JBrowse link
pancreatic ductal adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2 ISO protein:increased expression:pancreas RGD PMID:19714807 RGD:2325658 NCBI chr12:36,042,924...36,054,080
Ensembl chr12:36,042,906...36,054,086 		JBrowse link
G Akr7a5 aldo-keto reductase family 7, member A5 ISO protein:increased expression:pancreas RGD PMID:19077459 RGD:2325696 NCBI chr 4:139,038,005...139,046,097
Ensembl chr 4:139,038,055...139,045,737 		JBrowse link
G Calr calreticulin ameliorates ISO human cells in mouse model
human cells in a mouse model		 RGD PMID:33028359 PMID:29072694 RGD:150520160, RGD:150521706 NCBI chr 8:85,568,717...85,573,560
Ensembl chr 8:85,568,479...85,573,563 		JBrowse link
G Ccnd1 cyclin D1 severity ISO DNA:snp:exon:c.870G>A (human)
protein:increased expression:pancreas (human)		 RGD PMID:25470788 PMID:22939953 RGD:13462050, RGD:13462062 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
G Cd59b CD59b antigen disease_progression ISO protein:increased expression:blood (human) RGD PMID:32663515 RGD:151660329 NCBI chr 2:103,900,127...103,920,619
Ensembl chr 2:103,896,142...103,921,534 		JBrowse link
G Cdk4 cyclin dependent kinase 4 severity ISO protein:increased expression:pancreas, islet of Langerhans (human) RGD PMID:29735403 RGD:13781899 NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789 		JBrowse link
G Cfhr2 complement factor H-related 2 disease_progression ISO protein:decreased expression:blood (human) RGD PMID:32663515 RGD:151660329 NCBI chr 1:139,738,030...139,786,437
Ensembl chr 1:139,731,905...139,786,456 		JBrowse link
G E2f1 E2F transcription factor 1 severity ISO protein:increased expression:pancreatic ductal cell, nucleus (human)
DNA:amplification: : (human)		 RGD PMID:12650514 PMID:17233815 PMID:27573434 RGD:13838735, RGD:13838739, RGD:13838738 NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812 		JBrowse link
G Foxm1 forkhead box M1 disease_progression ISO RGD PMID:24859161 RGD:156430321 NCBI chr 6:128,339,957...128,352,849
Ensembl chr 6:128,339,930...128,353,109 		JBrowse link
G Fubp1 far upstream element (FUSE) binding protein 1 ISO mRNA:increased expression:pancreatic duct (human) RGD PMID:32481602 RGD:151361197 NCBI chr 3:151,916,059...151,942,467
Ensembl chr 3:151,916,059...151,942,463 		JBrowse link
G Glipr2 GLI pathogenesis-related 2 disease_progression ISO protein:decreased expression:blood (human) RGD PMID:32663515 RGD:151660329 NCBI chr 4:43,957,702...43,979,118
Ensembl chr 4:43,957,401...43,979,118 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1, soluble treatment ISO human cells in a mouse model RGD PMID:23535601 RGD:13504844 NCBI chr19:43,488,191...43,514,743
Ensembl chr19:43,488,191...43,513,044 		JBrowse link
G Hspa8 heat shock protein 8 disease_progression ISO protein:decreased expression:blood (human) RGD PMID:32663515 RGD:151660329 NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383 		JBrowse link
G Ikbkb inhibitor of kappaB kinase beta susceptibility IMP RGD PMID:22264792 RGD:13838741 NCBI chr 8:23,149,228...23,196,605
Ensembl chr 8:23,149,228...23,196,605 		JBrowse link
G Jak1 Janus kinase 1 ISO mRNA:decreased expression:pancreatic ductal cell (human) RGD PMID:28677798 RGD:13838745 NCBI chr 4:101,009,171...101,122,493
Ensembl chr 4:101,009,564...101,122,479 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 severity
disease_progression		 IMP
IEP		 protein:increased phosphorylation:pancreas (mouse) RGD PMID:28837246 PMID:23237571 RGD:14348974, RGD:14348975 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115 		JBrowse link
G Mir155 microRNA 155 disease_progression ISO RGD PMID:28198398 RGD:25314300 NCBI chr16:84,511,028...84,511,092
Ensembl chr16:84,511,028...84,511,092 		JBrowse link
G Mir494 microRNA 494 disease_progression
ameliorates		 ISO RGD PMID:24859161 PMID:24859161 RGD:156430321, RGD:156430321 NCBI chr12:109,681,752...109,681,836
Ensembl chr12:109,681,752...109,681,836 		JBrowse link
G Pgf placental growth factor severity IMP associated with obesity RGD PMID:26861455 RGD:14349030 NCBI chr12:85,213,413...85,224,087
Ensembl chr12:85,213,409...85,224,564 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO mRNA, protein:increased expression:pancreas (human) RGD PMID:20876794 RGD:14390130 NCBI chr12:32,223,128...32,258,675
Ensembl chr12:32,223,472...32,258,658 		JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 severity ISO human cells in a mouse model RGD PMID:15591514 RGD:14390084 NCBI chr 8:71,220,820...71,229,356
Ensembl chr 8:71,220,820...71,229,357 		JBrowse link
G Pld1 phospholipase D1 severity ISO protein:increased expression:pancreas (human) RGD PMID:27713167 RGD:14392801 NCBI chr 3:27,992,636...28,187,388
Ensembl chr 3:27,992,844...28,187,511 		JBrowse link
G Ptprb protein tyrosine phosphatase receptor type B disease_progression ISO protein:decreased expression:blood (human) RGD PMID:32663515 RGD:151660329 NCBI chr10:116,111,407...116,225,443
Ensembl chr10:116,111,428...116,225,440 		JBrowse link
G Ptprm protein tyrosine phosphatase receptor type M disease_progression ISO protein:decreased expression:blood (human) RGD PMID:32663515 RGD:151660329 NCBI chr17:66,973,843...67,661,486
Ensembl chr17:66,973,942...67,661,452 		JBrowse link
G Rac1 Rac family small GTPase 1 ISO
IEP		 mRNA:increased expression:pancreas (human)
mRNA, protein:increased expression:pancreas (mouse)		 RGD PMID:23334332 PMID:21684285 RGD:14392806, RGD:14392816 NCBI chr 5:143,491,236...143,513,786
Ensembl chr 5:143,489,389...143,513,791 		JBrowse link
G Rala v-ral simian leukemia viral oncogene A (ras related) ISO mRNA:increased expression:pancreas (human) RGD PMID:29113235 RGD:14394418 NCBI chr13:18,055,160...18,118,802
Ensembl chr13:18,055,156...18,118,824 		JBrowse link
G S100a8 S100 calcium binding protein A8 (calgranulin A) disease_progression ISO protein:increased expression:blood (human) RGD PMID:32663515 RGD:151660329 NCBI chr 3:90,576,378...90,577,341
Ensembl chr 3:90,576,285...90,577,342 		JBrowse link
G Smad2 SMAD family member 2 severity ISO RGD PMID:26908446 RGD:14394493 NCBI chr18:76,369,898...76,444,819
Ensembl chr18:76,374,651...76,444,034 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 ameliorates ISO protein:decreased expression:pancreas (human) RGD PMID:8253361 RGD:155630628 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 ameliorates ISO protein:decreased expression:pancreas (human) RGD PMID:8253361 RGD:155630628 NCBI chr 1:186,354,984...186,441,504
Ensembl chr 1:186,354,989...186,438,186 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 ameliorates ISO protein:decreased expression:pancreas (human) RGD PMID:8253361 RGD:155630628 NCBI chr12:86,103,517...86,125,815
Ensembl chr12:86,103,519...86,125,815 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor I ameliorates ISO human cell line in a mouse model RGD PMID:17297450 RGD:155630637 NCBI chr 4:47,353,258...47,414,926
Ensembl chr 4:47,353,222...47,414,931 		JBrowse link
G Vegfd vascular endothelial growth factor D ISO protein:increased expression:blood serum (human) RGD PMID:21410412 RGD:155630646 NCBI chr  X:163,156,282...163,185,643
Ensembl chr  X:163,156,374...163,185,646 		JBrowse link
G Vnn1 vanin 1 disease_progression ISO protein:increased expression:blood (human) RGD PMID:32663515 RGD:151660329 NCBI chr10:23,770,586...23,781,242
Ensembl chr10:23,770,586...23,781,241 		JBrowse link
pancreatic ductal carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 2200002D01Rik RIKEN cDNA 2200002D01 gene ISO CTD Direct Evidence: marker/mechanism CTD PMID:35142956 NCBI chr 7:28,946,946...28,947,892
Ensembl chr 7:28,945,986...28,947,891 		JBrowse link
G Ace angiotensin I converting enzyme ISO mRNA, protein:increased expression:pancreas RGD PMID:17481528 RGD:2325211 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790 		JBrowse link
G Ace2 angiotensin converting enzyme 2 ISO protein:decreased expression:pancreas RGD PMID:19212105 RGD:2325210 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416 		JBrowse link
G Adam8 a disintegrin and metallopeptidase domain 8 disease_progression ISO mRNA:increased expression:pancreas RGD PMID:17979891 RGD:2325243 NCBI chr 7:139,558,845...139,573,016
Ensembl chr 7:139,558,845...139,572,475 		JBrowse link
G Adam9 ADAM metallopeptidase domain 9 disease_progression ISO protein:altered localization:cytoplasm RGD PMID:14997207 RGD:2325249 NCBI chr 8:25,439,627...25,507,138
Ensembl chr 8:25,439,627...25,506,943 		JBrowse link
G Agr2 anterior gradient 2 ISO mRNA:increased expression:pancreas RGD PMID:19609859 RGD:2325659 NCBI chr12:36,042,924...36,054,080
Ensembl chr12:36,042,906...36,054,086 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a ISO CTD Direct Evidence: marker/mechanism CTD PMID:17481528 NCBI chr13:30,520,339...30,566,850
Ensembl chr13:30,520,424...30,566,850 		JBrowse link
G Alb albumin disease_progression ISO RGD PMID:19011933 RGD:2325677 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461 		JBrowse link
G Anxa2 annexin A2 disease_progression ISO mRNA, protein:increased expression, altered localization:pancreas, plasma membrane RGD PMID:19260470 PMID:16450333 RGD:2317307, RGD:2325731 NCBI chr 9:69,360,978...69,399,074
Ensembl chr 9:69,360,902...69,399,077 		JBrowse link
G Anxa5 annexin A5 ISO protein:increased expression:pancreas RGD PMID:19488907 RGD:2317538 NCBI chr 3:36,503,072...36,530,036
Ensembl chr 3:36,503,072...36,530,043 		JBrowse link
G Anxa8 annexin A8 ISO mRNA:increased expression:pancreas RGD PMID:18223320 RGD:2325735 NCBI chr14:33,807,936...33,822,528
Ensembl chr14:33,807,938...33,822,528 		JBrowse link
G Apoc1 apolipoprotein C-I ISO RGD PMID:15876873 RGD:2325793 NCBI chr 7:19,423,405...19,426,584
Ensembl chr 7:19,423,406...19,426,585 		JBrowse link
G Arg2 arginase type II ISO CTD Direct Evidence: marker/mechanism CTD PMID:23424623 NCBI chr12:79,177,562...79,203,075
Ensembl chr12:79,177,551...79,203,075 		JBrowse link
G Bmi1 Bmi1 polycomb ring finger oncogene IEP
ISO		 protein:increased expression:pancreas
protein:increased expression:exocrine pancreas: 		RGD PMID:19585519 PMID:19585519 RGD:9491843, RGD:9491843 NCBI chr 2:18,681,953...18,691,440
Ensembl chr 2:18,681,829...18,691,440 		JBrowse link
G Calr calreticulin ISO protein:increased expression:pancreatic duct RGD PMID:15289361 RGD:2326165 NCBI chr 8:85,568,717...85,573,560
Ensembl chr 8:85,568,479...85,573,563 		JBrowse link
G Cbx7 chromobox 7 disease_progression ISO protein:decreased expression:pancreas RGD PMID:20185297 RGD:9587360 NCBI chr15:79,800,005...79,855,344
Ensembl chr15:79,800,008...79,855,320 		JBrowse link
G Cckar cholecystokinin A receptor ISO protein:decreased expression:pancreas
mRNA:increased expression:pancreatic duct		 RGD PMID:12851875 PMID:9239407 RGD:4110816, RGD:4110818 NCBI chr 5:53,855,827...53,865,046
Ensembl chr 5:53,855,118...53,865,047 		JBrowse link
G Cckbr cholecystokinin B receptor ISO protein:decreased expression:pancreas RGD PMID:12851875 RGD:4110816 NCBI chr 7:105,075,201...105,085,546
Ensembl chr 7:105,074,938...105,120,105 		JBrowse link
G Ccnd1 cyclin D1 severity ISO protein:increased expression:pancreas (human) RGD PMID:17420962 RGD:13462063 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
G Cd40 CD40 antigen treatment IDA
ISO		 protein:increased expression:dendritic cell RGD PMID:21436454 PMID:23983255 PMID:20976171 RGD:5490301, RGD:11522743, RGD:5490524 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868 		JBrowse link
G Cdk6 cyclin dependent kinase 6 treatment ISO human cells in a mouse model RGD PMID:24389175 RGD:13782187 NCBI chr 5:3,391,004...3,581,008
Ensembl chr 5:3,391,485...3,581,008 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A disease_progression ISO RGD PMID:17671118 RGD:8662851 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:24986516 NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890 		JBrowse link
G Cldn4 claudin 4 ISO RGD PMID:15693851 RGD:2317592 NCBI chr 5:134,973,977...134,975,788
Ensembl chr 5:134,973,973...134,975,788 		JBrowse link
G Cxcl11 chemokine (C-X-C motif) ligand 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24979617 NCBI chr 5:92,507,403...92,511,155
Ensembl chr 5:92,507,403...92,513,344 		JBrowse link
G Dnmt1 DNA methyltransferase 1 disease_progression ISO protein:increased expression:pancreas
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:29844410 PMID:19424621 RGD:9588974 NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184 		JBrowse link
G Dnmt3b DNA methyltransferase 3B disease_progression ISO RGD PMID:22919364 RGD:9589121 NCBI chr 2:153,491,332...153,529,650
Ensembl chr 2:153,491,370...153,529,650 		JBrowse link
G Dtx1 deltex 1, E3 ubiquitin ligase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr 5:120,818,268...120,850,879
Ensembl chr 5:120,818,267...120,849,992 		JBrowse link
G Dtx4 deltex 4, E3 ubiquitin ligase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr19:12,443,700...12,479,509
Ensembl chr19:12,443,702...12,478,818 		JBrowse link
G Egf epidermal growth factor disease_progression ISO protein:increased expression: : RGD PMID:18505086 RGD:2317644 NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965 		JBrowse link
G Fasl Fas ligand ISO protein:increased expression:pancreas, liver RGD PMID:10547193 PMID:15375495 RGD:2317747, RGD:2317741 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064 		JBrowse link
G Fgf2 fibroblast growth factor 2 disease_progression ISO RGD PMID:12717266 PMID:18704599 RGD:2317758, RGD:2317756 NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257 		JBrowse link
G Fscn1 fascin actin-bundling protein 1 disease_progression ISO protein:increased expression:pancreas RGD PMID:12109856 RGD:2317790 NCBI chr 5:142,946,110...142,958,944
Ensembl chr 5:142,946,098...142,958,940 		JBrowse link
G Gpnmb glycoprotein (transmembrane) nmb ISO CTD Direct Evidence: marker/mechanism CTD PMID:24979617 NCBI chr 6:49,013,449...49,044,413
Ensembl chr 6:49,013,480...49,047,863 		JBrowse link
G Gstp1 glutathione S-transferase, pi 1 resistance ISO DNA:methylation: :
mRNA, protein:increased expression:pancreas		 RGD PMID:16537562 PMID:17265526 PMID:12488200 RGD:2317809, RGD:2317806, RGD:2317811 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985 		JBrowse link
G Hdac1 histone deacetylase 1 disease_progression ISO protein:increased expression:pancreas RGD PMID:19424621 RGD:9588974 NCBI chr 4:129,409,897...129,436,516
Ensembl chr 4:129,409,897...129,436,506 		JBrowse link
G Heatr1 HEAT repeat containing 1 treatment ISO RGD PMID:26676747 RGD:10761108 NCBI chr13:12,410,256...12,453,774
Ensembl chr13:12,409,908...12,455,170 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr16:29,883,259...29,886,614
Ensembl chr16:29,883,202...29,886,614 		JBrowse link
G Hey1 hairy/enhancer-of-split related with YRPW motif 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr 3:8,728,419...8,732,098
Ensembl chr 3:8,728,419...8,732,316 		JBrowse link
G Hey2 hairy/enhancer-of-split related with YRPW motif 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr10:30,708,355...30,718,779
Ensembl chr10:30,708,355...30,718,797 		JBrowse link
G Hspa1a heat shock protein 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:17234771 NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132 		JBrowse link
G Hspa1b heat shock protein 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:17234771 NCBI chr17:35,175,405...35,178,214
Ensembl chr17:35,175,412...35,178,214 		JBrowse link
G Igf1 insulin-like growth factor 1 IDA RGD PMID:20098680 RGD:2317639 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904 		JBrowse link
G Igf1r insulin-like growth factor I receptor ISO protein:increased expression:pancreas RGD PMID:14506643 PMID:14627343 RGD:2317652, RGD:2317649 NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416 		JBrowse link
G Il4 interleukin 4 ISO RGD PMID:17942922 RGD:2317264 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Il4ra interleukin 4 receptor, alpha ISO protein:increased expression:pancreas RGD PMID:17942922 RGD:2317264 NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646 		JBrowse link
G Ins2 insulin II ISO Glucagon/insulin RGD PMID:19571666 RGD:2317248 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118 		JBrowse link
G Jag1 jagged 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr 2:136,923,371...136,958,440
Ensembl chr 2:136,923,376...136,958,564 		JBrowse link
G Jag2 jagged 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr12:112,871,439...112,893,437
Ensembl chr12:112,871,439...112,893,396 		JBrowse link
G Kdm2b lysine (K)-specific demethylase 2B severity ISO mRNA, protein:increased expression:pancreas (human) RGD PMID:23321669 RGD:9588253 NCBI chr 5:123,008,727...123,127,333
Ensembl chr 5:123,008,728...123,127,886 		JBrowse link
G Kitl kit ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:24979617 NCBI chr10:99,851,477...99,936,278
Ensembl chr10:99,851,492...99,936,278 		JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:25347530 PMID:30654191 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965 		JBrowse link
G Krt7 keratin 7 disease_progression ISO RGD PMID:19260470 RGD:2317307 NCBI chr15:101,310,284...101,325,687
Ensembl chr15:101,308,924...101,328,194 		JBrowse link
G L1cam L1 cell adhesion molecule severity ISO protein:increased expression:pancreas (human) RGD PMID:20162456 RGD:6483447 NCBI chr  X:72,897,384...72,924,843
Ensembl chr  X:72,897,384...72,939,711 		JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34686948 NCBI chr 4:31,963,659...32,023,470
Ensembl chr 4:31,964,097...32,023,467 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 treatment ISO human cells in mouse model RGD PMID:20179210 RGD:14348973 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991 		JBrowse link
G Mcm7 minichromosome maintenance complex component 7 ISO mRNA, protein:increased expression:pancreatic duct RGD PMID:15548371 RGD:2317697 NCBI chr 5:138,162,845...138,170,675
Ensembl chr 5:138,162,845...138,170,684 		JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 severity
onset		 ISO protein:increased expression:pancreas (human)
DNA:snp:promoter, intron:IVS1+309T>G (human)		 RGD PMID:15810085 PMID:19752772 RGD:2317416, RGD:2317414 NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663 		JBrowse link
G Men1 multiple endocrine neoplasia 1 ISO protein:decreased expression:pancreas RGD PMID:19170121 RGD:2317294 NCBI chr19:6,385,009...6,390,924
Ensembl chr19:6,385,009...6,390,921 		JBrowse link
G Met met proto-oncogene ISO protein:increased expression:pancreatic duct (human) RGD PMID:7866999 RGD:2317530 NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase susceptibility ISO DNA:missense mutation:cds:p.L84F rs12917 (human)
protein:increased activity, increased expression:ductal adenocarcinoma (human)		 RGD PMID:16844323 PMID:9393761 RGD:2317648, RGD:2317664 NCBI chr 7:136,496,315...136,732,001
Ensembl chr 7:136,496,343...136,731,995 		JBrowse link
G Mir142 microRNA 142 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29844410 NCBI chr11:87,647,690...87,647,753
Ensembl chr11:87,647,690...87,647,753 		JBrowse link
G Mir873a microRNA 873a ISO CTD Direct Evidence: therapeutic CTD PMID:30654191 NCBI chr 4:36,668,510...36,668,586
Ensembl chr 4:36,668,510...36,668,586 		JBrowse link
G Mmp2 matrix metallopeptidase 2 severity ISO protein:increased expression:pancreas RGD PMID:17377415 RGD:2325746 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO protein:increased expression:pancreas, serum
protein:increased expression:blood		 RGD PMID:18706098 PMID:20332475 RGD:2325844, RGD:2325830 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770 		JBrowse link
G Msln mesothelin disease_progression ISO protein:increased secretion:serum
CTD Direct Evidence: marker/mechanism
DNA:hypomethylation:5'UTR		 CTD
RGD		 PMID:14576474 PMID:21775916 PMID:25347530 PMID:19818733 PMID:12874021 RGD:2326055, RGD:2326065 NCBI chr17:25,967,587...25,973,352
Ensembl chr17:25,967,587...25,973,352 		JBrowse link
G Muc1 mucin 1, transmembrane disease_progression ISO protein:increased expression, altered localization:pancreas RGD PMID:18713982 PMID:19109152 PMID:14681945 RGD:2324633, RGD:2324616, RGD:2317983 NCBI chr 3:89,136,363...89,140,688
Ensembl chr 3:89,136,364...89,140,688 		JBrowse link
G Muc3a mucin 3A, cell surface associated disease_progression ISO mRNA:increased expression:pancreas RGD PMID:12657964 RGD:2324946 NCBI chr 5:137,243,263...137,276,564
Ensembl chr 5:137,243,270...137,246,852 		JBrowse link
G Muc4 mucin 4 disease_progression ISO mRNA:increased expression:pancreas
protein:increased expression:pancreas		 RGD PMID:12657964 PMID:16049287 RGD:2324946, RGD:2324942 NCBI chr16:32,555,089...32,602,786
Ensembl chr16:32,555,015...32,602,754 		JBrowse link
G Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric disease_progression ISO mRNA:increased expression:pancreas RGD PMID:7657125 PMID:10227724 RGD:2324986, RGD:2324907 NCBI chr 7:141,342,695...141,372,964
Ensembl chr 7:141,342,709...141,372,968 		JBrowse link
G Muc5b mucin 5, subtype B, tracheobronchial ISO mRNA:increased expression:pancreas RGD PMID:7657125 RGD:2324986 NCBI chr 7:141,392,796...141,426,826
Ensembl chr 7:141,392,807...141,426,821 		JBrowse link
G Ndrg1 N-myc downstream regulated gene 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16778198 NCBI chr15:66,801,167...66,841,490
Ensembl chr15:66,801,167...66,841,489 		JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21489257 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 ISO protein:increased expression:pancreas (human) RGD PMID:17492507 RGD:5132867 NCBI chr11:93,849,751...93,859,341
Ensembl chr11:93,847,805...93,859,347 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible IMP RGD PMID:12660813 RGD:2325254 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Notch1 notch 1 IMP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19208345 PMID:20484026 PMID:19028876 RGD:2325323, RGD:2325324 NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675 		JBrowse link
G Notch3 notch 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr17:32,339,794...32,385,869
Ensembl chr17:32,339,794...32,385,826 		JBrowse link
G Notch4 notch 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr17:34,783,257...34,807,517
Ensembl chr17:34,783,242...34,807,477 		JBrowse link
G Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 disease_progression ISO protein:increased expression:pancreas RGD PMID:11295066 PMID:10209957 RGD:2325660, RGD:2325663 NCBI chr 7:77,825,711...78,228,865
Ensembl chr 7:77,825,707...78,387,760 		JBrowse link
G Osm oncostatin M ISO CTD Direct Evidence: marker/mechanism CTD PMID:24979617 NCBI chr11:4,186,831...4,191,027
Ensembl chr11:4,186,420...4,191,026 		JBrowse link
G Palld palladin, cytoskeletal associated protein ISO protein:increased expression, alternative form:pancreas, fibroblast RGD PMID:17404500 RGD:2325781 NCBI chr 8:61,964,465...62,355,741
Ensembl chr 8:61,964,467...62,355,724 		JBrowse link
G Pax6 paired box 6 ISO protein:increased expression:pancreatic duct (human) RGD PMID:17849422 RGD:8552381 NCBI chr 2:105,499,241...105,528,755
Ensembl chr 2:105,499,245...105,527,709 		JBrowse link
G Pms1 PMS1 homolog 1, mismatch repair system component ISO protein:increased expression:pancreatic duct RGD PMID:15856462 RGD:2324870 NCBI chr 1:53,225,794...53,336,190
Ensembl chr 1:53,228,346...53,336,177 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma disease_progression ISO RGD PMID:19396032 RGD:2317461 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP RGD PMID:18670639 RGD:2317185 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) ISO CTD Direct Evidence: marker/mechanism CTD PMID:34686948 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Rnf2 ring finger protein 2 IEP protein:increased expression:pancreas RGD PMID:19585519 RGD:9491843 NCBI chr 1:151,345,159...151,376,562
Ensembl chr 1:151,333,755...151,376,706 		JBrowse link
G Rxra retinoid X receptor alpha severity ISO RGD PMID:19396032 RGD:2317461 NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969 		JBrowse link
G Serpina1e serine (or cysteine) peptidase inhibitor, clade A, member 1E ISO mRNA, protein:increased expression:pancreas RGD PMID:12488200 RGD:2317811 NCBI chr12:103,913,190...103,923,156
Ensembl chr12:103,913,190...103,925,234 		JBrowse link
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 IEP protein:increased expression:pancreatic duct RGD PMID:19252908 RGD:2324975 NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508 		JBrowse link
G Smad4 SMAD family member 4 disease_progression ISO RGD PMID:15173084 RGD:21066334 NCBI chr18:73,767,861...73,836,862
Ensembl chr18:73,772,080...73,836,851 		JBrowse link
G Smo smoothened, frizzled class receptor ISO RGD PMID:16826192 RGD:2324981 NCBI chr 6:29,735,480...29,761,359
Ensembl chr 6:29,735,502...29,761,364 		JBrowse link
G Stk11 serine/threonine kinase 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26887594 NCBI chr10:79,951,602...79,966,513
Ensembl chr10:79,951,637...79,966,516 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 disease_progression ISO RGD PMID:16101174 RGD:2325019 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor II disease_progression IMP
ISO		 mRNA:increased expresssion:pancreas RGD PMID:17114585 PMID:10547197 RGD:2317498, RGD:2317500 NCBI chr 9:115,916,763...116,004,431
Ensembl chr 9:115,913,361...116,004,428 		JBrowse link
G Thbs1 thrombospondin 1 disease_progression ISO DNA:hypermethylation:promoter (human) RGD PMID:12429967 PMID:19065635 RGD:2325025, RGD:2325022 NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614 		JBrowse link
G Tmprss3 transmembrane protease, serine 3 ISO RGD PMID:14695172 RGD:2325152 NCBI chr17:31,398,237...31,419,478
Ensembl chr17:31,398,239...31,417,951 		JBrowse link
G Trp53 transformation related protein 53 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29844410 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Tsc2 TSC complex subunit 2 severity ISO RGD PMID:16213898 RGD:11568674 NCBI chr17:24,814,788...24,851,607
Ensembl chr17:24,814,790...24,851,604 		JBrowse link
G Tymp thymidine phosphorylase disease_progression ISO RGD PMID:19760965 RGD:2325155 NCBI chr15:89,255,834...89,261,282
Ensembl chr15:89,256,134...89,261,242 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:17481528 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor ISO DNA:hypermethylation:promoter (human) RGD PMID:19065635 RGD:2325022 NCBI chr 6:113,600,955...113,608,595
Ensembl chr 6:113,600,920...113,608,594 		JBrowse link
G Yeats2 YEATS domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34686948 NCBI chr16:19,959,803...20,051,323
Ensembl chr16:19,959,813...20,051,323 		JBrowse link
G Zzz3 zinc finger, ZZ domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34686948 NCBI chr 3:152,101,110...152,168,463
Ensembl chr 3:152,101,110...152,168,463 		JBrowse link
pancreatic endocrine carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 breast cancer 2, early onset ISO ClinVar Annotator: match by term: Neuroendocrine tumor of pancreas ClinVar PMID:15145354 PMID:22762150 PMID:25741868 PMID:29446198 NCBI chr 5:150,445,759...150,493,612
Ensembl chr 5:150,446,095...150,493,794 		JBrowse link
G Cux1 cut-like homeobox 1 exacerbates ISO protein:increased expression:pancreas (human) RGD PMID:32707646 RGD:153297777 NCBI chr 5:136,276,989...136,596,429
Ensembl chr 5:136,276,989...136,596,344 		JBrowse link
G Daxx Fas death domain-associated protein disease_progression ISO DNA:frameshift, frameshift mutations, nonsense mutation, missense mutations:CDS:multiple (human) RGD PMID:29212165 RGD:152025205 NCBI chr17:34,128,379...34,134,564
Ensembl chr17:34,128,388...34,134,564 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase ISO DNA:hypermethylation:promoter (human) RGD PMID:14501508 RGD:2317661 NCBI chr 7:136,496,315...136,732,001
Ensembl chr 7:136,496,343...136,731,995 		JBrowse link
G Palb2 partner and localizer of BRCA2 ISO ClinVar Annotator: match by term: Neuroendocrine tumor of pancreas ClinVar PMID:17200668 PMID:17200671 PMID:17200672 PMID:24136930 PMID:25099575 More... NCBI chr 7:121,706,485...121,732,203
Ensembl chr 7:121,706,485...121,732,208 		JBrowse link
G Pgf placental growth factor disease_progression
treatment		 ISO
IMP		 protein:increased expression:serum (human)
human cells in a mouse model		 RGD PMID:23463017 PMID:26861455 RGD:14349029, RGD:14349030 NCBI chr12:85,213,413...85,224,087
Ensembl chr12:85,213,409...85,224,564 		JBrowse link
pancreatic intraductal papillary-mucinous neoplasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 thymoma viral proto-oncogene 1 ISO DNA:missense mutation:cds:p.E17K (human) RGD PMID:24132918 RGD:13462042 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318 		JBrowse link
G Trp53 transformation related protein 53 ISO DNA:missense mutations: :multiple RGD PMID:28930868 RGD:14995501 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Vegfd vascular endothelial growth factor D ISO protein:increased expression:blood serum (human) RGD PMID:21410412 RGD:155630646 NCBI chr  X:163,156,282...163,185,643
Ensembl chr  X:163,156,374...163,185,646 		JBrowse link
Pancreatic Intraepithelial Neoplasia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agr2 anterior gradient 2 ISO protein:increased expression:pancreas RGD PMID:19714807 RGD:2325658 NCBI chr12:36,042,924...36,054,080
Ensembl chr12:36,042,906...36,054,086 		JBrowse link
G Bmi1 Bmi1 polycomb ring finger oncogene IEP
ISO		 protein:increased expression:pancreatic acinar cell:
protein:increased expression:exocrine pancreas: 		RGD PMID:19585519 PMID:19585519 RGD:9491843, RGD:9491843 NCBI chr 2:18,681,953...18,691,440
Ensembl chr 2:18,681,829...18,691,440 		JBrowse link
G Cbx7 chromobox 7 disease_progression ISO protein:decreased expression:pancreas RGD PMID:20185297 RGD:9587360 NCBI chr15:79,800,005...79,855,344
Ensembl chr15:79,800,008...79,855,320 		JBrowse link
G Ccnd1 cyclin D1 disease_progression ISO protein:increased expression:pancreas (human) RGD PMID:12882690 PMID:11751405 RGD:13462061, RGD:13464129 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO protein:increased expression:pancreas RGD PMID:19424621 RGD:9588974 NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184 		JBrowse link
G Hdac1 histone deacetylase 1 ISO protein:increased expression:pancreas RGD PMID:19424621 RGD:9588974 NCBI chr 4:129,409,897...129,436,516
Ensembl chr 4:129,409,897...129,436,506 		JBrowse link
G Ikbkb inhibitor of kappaB kinase beta severity
disease_progression		 IMP RGD PMID:22406536 PMID:22056382 RGD:13838740, RGD:13838742 NCBI chr 8:23,149,228...23,196,605
Ensembl chr 8:23,149,228...23,196,605 		JBrowse link
pancreatic mucinous cystadenoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kras Kirsten rat sarcoma viral oncogene homolog severity ISO DNA:mutations:cds: RGD PMID:28570009 RGD:14398747 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965 		JBrowse link
pancreatic solid pseudopapillary carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnd1 cyclin D1 severity ISO protein:increased expression:pancreas (human) RGD PMID:19248223 RGD:13462054 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
vipoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifna1 interferon alpha 1 ISO CTD Direct Evidence: therapeutic CTD PMID:17961653 NCBI chr 4:88,768,324...88,768,893
Ensembl chr 4:88,768,324...88,768,893 		JBrowse link
G Men1 multiple endocrine neoplasia 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17961653 NCBI chr19:6,385,009...6,390,924
Ensembl chr19:6,385,009...6,390,921 		JBrowse link
G Sst somatostatin ISO CTD Direct Evidence: therapeutic CTD PMID:2868874 NCBI chr16:23,708,327...23,710,041
Ensembl chr16:23,708,323...23,709,708 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16268
    disease of anatomical entity 15860
      endocrine system disease 6555
        pancreas disease 1017
          Pancreatic Neoplasms 425
            Pancreatic Benign Neoplasm + 14
            islet cell tumor + 30
            pancreatic cancer + 422
paths to the root