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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Pancreatic Neoplasms
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Accession:DOID:9003100 term browser browse the term
Synonyms:exact_synonym: Pancreas Neoplasms;   pancreas neoplasm;   pancreatic neoplasm
 narrow_synonym: Borderline Exocrine Pancreatic Neoplasm
 xref: EFO:0003860;   EFO:1000133;   NCI:C34035


show annotations for term's descendants           Sort by:
Adult Pancreatic Cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHR aryl hydrocarbon receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:12203118 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
duodenal gastrinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MEN1 menin 1 IAGP associated with Neuroendocrine Tumors; DNA:loss of heterozygosity: : RGD PMID:17135306 RGD:2317341 NCBI chr11:64,803,516...64,811,294
Ensembl chr11:64,803,510...64,811,294 		JBrowse link
Familial Pancreatic Carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA4 apolipoprotein A4 IEP mRNA:increased expression:pancreas, carcinoma (human) RGD PMID:16815451 RGD:5685662 NCBI chr11:116,820,700...116,823,304
Ensembl chr11:116,820,700...116,823,304 		JBrowse link
G ATM ATM serine/threonine kinase IAGP ClinVar Annotator: match by term: Familial pancreatic carcinoma ClinVar PMID:8755918 PMID:9443866 PMID:9463314 PMID:9887333 PMID:10330348 More... NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102 		JBrowse link
G BARD1 BRCA1 associated RING domain 1 IAGP ClinVar Annotator: match by term: Familial pancreatic carcinoma ClinVar PMID:25085752 PMID:25741868 PMID:26315354 PMID:26467025 PMID:26787654 More... NCBI chr 2:214,725,646...214,809,683
Ensembl chr 2:214,725,646...214,809,683 		JBrowse link
G C11orf65 chromosome 11 open reading frame 65 IAGP ClinVar Annotator: match by term: Familial pancreatic carcinoma ClinVar PMID:28492532 NCBI chr11:108,308,519...108,469,881
Ensembl chr11:108,308,519...108,467,531 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A IAGP ClinVar Annotator: match by term: Familial pancreatic carcinoma ClinVar PMID:7640518 PMID:7647780 PMID:7987387 PMID:8668202 PMID:9823374 More... NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase IAGP ClinVar Annotator: match by term: Familial pancreatic carcinoma ClinVar PMID:1875403 PMID:2547513 PMID:3627975 PMID:7773929 PMID:8439212 More... NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936 		JBrowse link
G SMAD4 SMAD family member 4 IAGP ClinVar Annotator: match by term: Familial pancreatic carcinoma ClinVar PMID:25741868 PMID:26467025 PMID:26900293 PMID:27611364 PMID:28283864 More... NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,528...51,085,045 		JBrowse link
G TP53 tumor protein p53 IAGP ClinVar Annotator: match by term: Familial pancreatic carcinoma ClinVar PMID:1565143 PMID:1565144 PMID:1631137 PMID:1683921 PMID:1978757 More... NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
gastrinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IGF1R insulin like growth factor 1 receptor IEP mRNA and protein: increased expression::poor prognosis for high expression RGD PMID:15867218 RGD:7242847 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530 		JBrowse link
G MEN1 menin 1 IAGP
EXP		 DNA:mutations: :
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:17961653 PMID:15944766 RGD:2317354 NCBI chr11:64,803,516...64,811,294
Ensembl chr11:64,803,510...64,811,294 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase severity IEP associated with Zollinger-Ellison Syndrome; mRNA:increased expression:tumor (human) RGD PMID:12114431 RGD:2317605 NCBI chr 7:116,672,196...116,798,377
Ensembl chr 7:116,672,196...116,798,377 		JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase IAGP DNA:hypomethylation:promoter (human) RGD PMID:17278096 RGD:2317340 NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983 		JBrowse link
G SLC2A2 solute carrier family 2 member 2 IEP mRNA:decreased expression:pancreatic islet RGD PMID:8421107 PMID:12114701 RGD:2324977, RGD:2324976 NCBI chr 3:170,996,347...171,026,720
Ensembl chr 3:170,996,347...171,026,743 		JBrowse link
Gastro-Enteropancreatic Neuroendocrine Tumor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATM ATM serine/threonine kinase disease_progression IEP associated with Neoplasm Metastasis;mRNA, protein: decreased expression:gastrointestinal system, multiple (human) RGD PMID:22485171 RGD:150340716 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102 		JBrowse link
G ATRX ATRX chromatin remodeler severity IEP RGD PMID:26026117 RGD:127285385 NCBI chr  X:77,504,880...77,786,216
Ensembl chr  X:77,504,880...77,786,233 		JBrowse link
G CD53 CD53 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 1:110,871,210...110,899,922
Ensembl chr 1:110,871,188...110,899,936 		JBrowse link
G CD86 CD86 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139 		JBrowse link
G CIITA class II major histocompatibility complex transactivator EXP CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr16:10,866,206...10,943,021
Ensembl chr16:10,866,222...10,943,021 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 severity IEP protein:increased expression:colon (human) RGD PMID:26259237 RGD:11530617 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177 		JBrowse link
G DAXX death domain associated protein severity IEP RGD PMID:26026117 RGD:127285385 NCBI chr 6:33,318,558...33,322,959
Ensembl chr 6:33,318,558...33,323,016 		JBrowse link
G EOMES eomesodermin EXP CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 3:27,715,953...27,722,713
Ensembl chr 3:27,715,949...27,722,711 		JBrowse link
G GATA3 GATA binding protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr10:8,045,333...8,075,198
Ensembl chr10:8,045,378...8,075,198 		JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor EXP CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 1:92,473,043...92,486,925
Ensembl chr 1:92,473,043...92,486,925 		JBrowse link
G IKZF1 IKAROS family zinc finger 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 7:50,303,455...50,405,101
Ensembl chr 7:50,304,068...50,405,101 		JBrowse link
G IKZF3 IKAROS family zinc finger 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr17:39,757,715...39,864,312
Ensembl chr17:39,757,715...39,864,312 		JBrowse link
G IL10 interleukin 10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL2RB interleukin 2 receptor subunit beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr22:37,125,838...37,175,118
Ensembl chr22:37,118,666...37,175,118 		JBrowse link
G NOTCH2 notch receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 1:119,911,553...120,069,662
Ensembl chr 1:119,911,553...120,100,779 		JBrowse link
G POU2F2 POU class 2 homeobox 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr19:42,086,110...42,197,936
Ensembl chr19:42,086,110...42,196,585 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C EXP CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 1:198,638,713...198,757,476
Ensembl chr 1:198,638,457...198,759,342 		JBrowse link
G RUNX3 RUNX family transcription factor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr 1:24,899,511...24,965,138
Ensembl chr 1:24,899,511...24,965,121 		JBrowse link
G SERPINA1 serpin family A member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29915428 NCBI chr14:94,376,747...94,390,635
Ensembl chr14:94,376,747...94,390,693 		JBrowse link
Glucagonoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTC betacellulin IEP protein:increased expression:pancreas RGD PMID:10724350 RGD:2326087 NCBI chr 4:74,744,759...74,794,523
Ensembl chr 4:74,744,759...74,794,523 		JBrowse link
G MEN1 menin 1 ISO
EXP		 DNA:deletion:exon
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:17961653 PMID:20138042 RGD:2317288 NCBI chr11:64,803,516...64,811,294
Ensembl chr11:64,803,510...64,811,294 		JBrowse link
G SLC2A2 solute carrier family 2 member 2 IEP mRNA:decreased expression:pancreatic islet RGD PMID:8421107 PMID:12114701 RGD:2324977, RGD:2324976 NCBI chr 3:170,996,347...171,026,720
Ensembl chr 3:170,996,347...171,026,743 		JBrowse link
G SSTR4 somatostatin receptor 4 IEP RGD PMID:8132773 RGD:2324994 NCBI chr20:23,035,312...23,039,237
Ensembl chr20:23,035,312...23,039,237 		JBrowse link
insulinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADM adrenomedullin IEP protein:increased expression:pancreas, plasma RGD PMID:11331218 RGD:2325319 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397 		JBrowse link
G BTC betacellulin IEP protein:increased expression:pancreas RGD PMID:10724350 RGD:2326087 NCBI chr 4:74,744,759...74,794,523
Ensembl chr 4:74,744,759...74,794,523 		JBrowse link
G CD40 CD40 molecule ISO RGD PMID:17982058 RGD:5491180 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CUX1 cut like homeobox 1 disease_progression
exacerbates		 ISO
IEP		 mRNA:increased expression:pancreas (mouse)
protein:increased expression:pancreas (human)		 RGD PMID:25248790 PMID:25248790 RGD:152985543, RGD:152985543 NCBI chr 7:101,816,007...102,283,958
Ensembl chr 7:101,815,904...102,283,958 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 IEP protein:increased expression:pancreas RGD PMID:19013212 RGD:2317608 NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493 		JBrowse link
G INS insulin IDA protein:altered expression:blood
protein:altered localization:pancreas		 RGD PMID:8175958 PMID:2565624 RGD:2317266, RGD:2317268 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221 		JBrowse link
G MEN1 menin 1 disease_progression ISO
EXP		 DNA:deletion:exon
CTD Direct Evidence: marker/mechanism
DNA:deletions:exons		 CTD
RGD		 PMID:17961653 PMID:12941803 PMID:20138042 PMID:19208834 RGD:2317292, RGD:2317288, RGD:2317310 NCBI chr11:64,803,516...64,811,294
Ensembl chr11:64,803,510...64,811,294 		JBrowse link
G NCAM1 neural cell adhesion molecule 1 IEP protein:increased expression:pancreas RGD PMID:8972754 RGD:2326080 NCBI chr11:112,961,420...113,278,436
Ensembl chr11:112,961,275...113,278,436 		JBrowse link
G RPS15 ribosomal protein S15 ISO RGD PMID:3019805 RGD:61740 NCBI chr19:1,438,396...1,440,495
Ensembl chr19:1,438,358...1,440,495 		JBrowse link
G SLC2A2 solute carrier family 2 member 2 IEP mRNA:decreased expression:pancreatic islet
protein:increased expression:pancreatic B cell		 RGD PMID:8421107 PMID:12114701 RGD:2324977, RGD:2324976 NCBI chr 3:170,996,347...171,026,720
Ensembl chr 3:170,996,347...171,026,743 		JBrowse link
G TGFA transforming growth factor alpha IEP protein:increased expression:pancreas RGD PMID:8712689 RGD:2317472 NCBI chr 2:70,447,284...70,553,826
Ensembl chr 2:70,447,284...70,554,193 		JBrowse link
G TGFB1 transforming growth factor beta 1 IEP mRNA, protein:decreased expression:pancreatic islet RGD PMID:18058603 RGD:2325017 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
Islet Cell Adenomatosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAFA MAF bZIP transcription factor A IAGP ClinVar Annotator: match by term: Islet cell adenomatosis ClinVar
OMIM		 PMID:25741868 PMID:29339498 PMID:35406570 NCBI chr 8:143,428,064...143,430,732
Ensembl chr 8:143,419,182...143,430,732 		JBrowse link
islet cell tumor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATRX ATRX chromatin remodeler disease_progression IEP protein:decreased expression:pancreas: RGD PMID:24148618 RGD:9586032 NCBI chr  X:77,504,880...77,786,216
Ensembl chr  X:77,504,880...77,786,233 		JBrowse link
G CDK4 cyclin dependent kinase 4 IEP protein:increased expression:pancreas, islet of Langerhans (human) RGD PMID:22761470 RGD:13452384 NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013 		JBrowse link
G DAXX death domain associated protein disease_progression IAGP RGD PMID:21252315 RGD:9587819 NCBI chr 6:33,318,558...33,322,959
Ensembl chr 6:33,318,558...33,323,016 		JBrowse link
G PCSK1 proprotein convertase subtilisin/kexin type 1 ISO protein:increased expression:insulinoma (rat) RGD PMID:7925129 RGD:2308920 NCBI chr 5:96,390,333...96,433,248
Ensembl chr 5:96,390,333...96,434,143 		JBrowse link
Islet Cell Tumor Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AL139022.1 novel transcript, antisense to MAX IAGP ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:21685915 PMID:22452945 PMID:25741868 PMID:26070438 PMID:27838885 More... NCBI chr14:65,089,918...65,094,311
Ensembl chr14:65,082,034...65,094,212 		JBrowse link
G CHURC1-FNTB CHURC1-FNTB readthrough IAGP ClinVar Annotator: match by term: Chromaffinoma ClinVar NCBI chr14:64,914,361...65,062,655
Ensembl chr14:64,986,895...65,062,652
Ensembl chr14:64,986,895...65,062,652 		JBrowse link
G FNTB farnesyltransferase, CAAX box, subunit beta IAGP ClinVar Annotator: match by term: Chromaffinoma ClinVar NCBI chr14:64,986,895...65,062,650
Ensembl chr14:64,986,895...65,062,652 		JBrowse link
G LOC106736614 RET 5' regulatory region IAGP ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr10:43,072,914...43,077,291 JBrowse link
G LOC107303340 3p25 von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase Alu-mediated recombination region IAGP ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:7563486 PMID:7987306 PMID:8707293 PMID:8772572 PMID:8956040 More... NCBI chr 3:10,142,339...10,160,352 JBrowse link
G LOC126861339 BRD4-independent group 4 enhancer GRCh37_chr11:111957035-111958234 IAGP ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:10657297 PMID:11156372 PMID:11391796 PMID:11526495 PMID:12007193 More... NCBI chr11:112,086,311...112,087,510 JBrowse link
G LOC126861966 MED14-independent group 3 enhancer GRCh37_chr14:65471811-65473010 IAGP ClinVar Annotator: match by term: Chromaffinoma ClinVar NCBI chr14:65,005,093...65,006,292 JBrowse link
G LOC129929541 ATAC-STARR-seq lymphoblastoid active region 276 IAGP ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:25741868 PMID:28492532 NCBI chr 1:17,018,964...17,019,013 JBrowse link
G LOC129929542 ATAC-STARR-seq lymphoblastoid active region 277 IAGP ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:9536098 PMID:16317055 PMID:16472267 PMID:16912137 PMID:17376234 More... NCBI chr 1:17,053,912...17,053,971 JBrowse link
G LOC129934333 ATAC-STARR-seq lymphoblastoid silent region 11759 IAGP ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:20154675 PMID:20923864 PMID:21156949 PMID:22541004 PMID:25741868 More... NCBI chr 2:96,265,257...96,265,566 JBrowse link
G LOC130055850 ATAC-STARR-seq lymphoblastoid silent region 5847 IAGP ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:22452945 PMID:25741868 PMID:26070438 PMID:28492532 PMID:34130653 NCBI chr14:65,102,102...65,102,451 JBrowse link
G MAX MYC associated factor X IAGP ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:21685915 PMID:22452945 PMID:23666964 PMID:25741868 PMID:26070438 More... NCBI chr14:65,006,101...65,102,695
Ensembl chr14:65,006,174...65,102,695 		JBrowse link
G MPZ myelin protein zero IAGP ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:12807974 PMID:17468193 PMID:19454582 PMID:23342407 PMID:24033266 More... NCBI chr 1:161,303,600...161,309,968
Ensembl chr 1:161,304,735...161,309,968 		JBrowse link
G NF1 neurofibromin 1 IAGP ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:1568247 PMID:8264648 PMID:8499944 PMID:8499945 PMID:8669813 More... NCBI chr17:31,094,927...31,377,677
Ensembl chr17:31,094,927...31,382,116 		JBrowse link
G RET ret proto-oncogene IAGP ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:2008030 PMID:2660074 PMID:2904651 PMID:3078962 PMID:7536460 More... NCBI chr10:43,077,069...43,130,351
Ensembl chr10:43,077,064...43,130,351 		JBrowse link
G SDHAF2 succinate dehydrogenase complex assembly factor 2 IAGP ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:28492532 NCBI chr11:61,430,124...61,446,733
Ensembl chr11:61,430,042...61,446,839 		JBrowse link
G SDHB succinate dehydrogenase complex iron sulfur subunit B IAGP ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:490809 PMID:2308387 PMID:9509062 PMID:9536098 PMID:11404820 More... NCBI chr 1:17,018,722...17,054,032
Ensembl chr 1:17,018,664...17,054,151 		JBrowse link
G SDHC succinate dehydrogenase complex subunit C IAGP ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:12807974 PMID:17468193 PMID:19454582 PMID:22517554 PMID:22703879 More... NCBI chr 1:161,314,381...161,363,206
Ensembl chr 1:161,314,381...161,363,206 		JBrowse link
G SDHD succinate dehydrogenase complex subunit D IAGP ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:1945482 PMID:8981955 PMID:9536098 PMID:9683583 PMID:10323245 More... NCBI chr11:112,086,873...112,095,794
Ensembl chr11:112,086,824...112,120,016 		JBrowse link
G TMEM127 transmembrane protein 127 IAGP ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:9536098 PMID:16266984 PMID:17576681 PMID:20154675 PMID:20923864 More... NCBI chr 2:96,248,514...96,265,997
Ensembl chr 2:96,248,500...96,266,047 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor IAGP ClinVar Annotator: match by term: Chromaffinoma ClinVar PMID:7563486 PMID:7987306 PMID:8707293 PMID:8772572 PMID:8956040 More... NCBI chr 3:10,141,778...10,153,667
Ensembl chr 3:10,141,778...10,153,676 		JBrowse link
Melanoma-Pancreatic Cancer Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN2A cyclin dependent kinase inhibitor 2A IAGP
EXP		 ClinVar Annotator: match by term: Melanoma-pancreatic cancer syndrome
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:2319082 PMID:2813514 PMID:5001868 PMID:7566978 PMID:7632931 More... NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301 		JBrowse link
G LOC130001603 ATAC-STARR-seq lymphoblastoid silent region 19811 IAGP ClinVar Annotator: match by term: Melanoma-pancreatic cancer syndrome ClinVar PMID:7881419 PMID:8570179 PMID:8653684 PMID:8727306 PMID:9425228 More... NCBI chr 9:21,974,815...21,974,864 JBrowse link
non-functioning pancreatic endocrine tumor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARID1A AT-rich interaction domain 1A exacerbates HEP protein:decreased expression:endocrine pancreas (human) RGD PMID:32282764 RGD:126790640 NCBI chr 1:26,696,015...26,782,104
Ensembl chr 1:26,693,236...26,782,104 		JBrowse link
G CDK4 cyclin dependent kinase 4 IEP associated with multiple endocrine neoplasia type 1;mRNA:increased expression:islet of Langerhans (human) RGD PMID:29149451 RGD:13781946 NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013 		JBrowse link
G CDK6 cyclin dependent kinase 6 IEP associated with multiple endocrine neoplasia type 1;mRNA:increased expression:islet of Langerhans (human) RGD PMID:29149451 RGD:13781946 NCBI chr 7:92,604,921...92,836,573
Ensembl chr 7:92,604,921...92,836,573 		JBrowse link
pancreatic acinar cell adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRAF B-Raf proto-oncogene, serine/threonine kinase IAGP DNA:missense mutation, gene fusions:multiple (human) RGD PMID:25266736 RGD:13462041 NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase disease_progression ISO RGD PMID:8569183 RGD:150523792 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050 		JBrowse link
pancreatic adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADGRB1 adhesion G protein-coupled receptor B1 IEP mRNA:decreased expression:pancreas RGD PMID:11875720 RGD:13831350 NCBI chr 8:142,449,649...142,545,007
Ensembl chr 8:142,449,430...142,545,009 		JBrowse link
G AKT3 AKT serine/threonine kinase 3 severity IEP mRNA:increased expression:pancreas (human) RGD PMID:27919956 RGD:13451128 NCBI chr 1:243,488,233...243,851,079
Ensembl chr 1:243,488,233...243,851,079 		JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 exacerbates HEP mRNA:increased expression:pancreas (human) RGD PMID:31964418 RGD:153344516 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 disease_progression HEP mRNA:increased expression:pancreas (human) RGD PMID:31964418 RGD:153344516 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 exacerbates HEP mRNA:increased expression:pancreas (human) RGD PMID:31964418 RGD:153344516 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636 		JBrowse link
G BIRC7 baculoviral IAP repeat containing 7 exacerbates HEP mRNA:increased expression:pancreas (human) RGD PMID:31964418 RGD:153344516 NCBI chr20:63,235,905...63,240,495
Ensembl chr20:63,235,883...63,240,495 		JBrowse link
G CBR4 carbonyl reductase 4 IAGP ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:9536098 PMID:17576681 PMID:25741868 PMID:28166811 PMID:28492532 NCBI chr 4:168,894,486...169,010,255
Ensembl chr 4:168,863,770...169,010,275 		JBrowse link
G CCND1 cyclin D1 severity IEP protein:increased expression:pancreas (human) RGD PMID:25053516 RGD:13462053 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CDK4 cyclin dependent kinase 4 treatment IDA human cells in a mouse model RGD PMID:22509328 RGD:13792559 NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013 		JBrowse link
G CDK6 cyclin dependent kinase 6 treatment IDA human cells in a mouse model RGD PMID:25050737 RGD:13782144 NCBI chr 7:92,604,921...92,836,573
Ensembl chr 7:92,604,921...92,836,573 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A IAGP DNA:missense mutations:cds:p.V126D, p.A148T (human) RGD PMID:16397522 RGD:8552283 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 IDA RGD PMID:21448932 RGD:11352272 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177 		JBrowse link
G E2F1 E2F transcription factor 1 treatment IDA Human cells in a mouse model RGD PMID:28797284 RGD:13838736 NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385 		JBrowse link
G GSTT1 glutathione S-transferase theta 1 IAGP RGD PMID:11854392 RGD:14700985
G HRG histidine rich glycoprotein disease_progression IEP RGD PMID:21713765 RGD:11041886 NCBI chr 3:186,666,014...186,678,234
Ensembl chr 3:186,660,216...186,678,234 		JBrowse link
G JAK1 Janus kinase 1 treatment IDA human cell line in a mouse model RGD PMID:29328487 RGD:13838743 NCBI chr 1:64,833,229...65,067,746
Ensembl chr 1:64,833,223...65,067,754 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 treatment
severity		 IMP
IEP		 human tissue in a mouse model
protein:increased expression:pancreas (human)		 RGD PMID:28849200 PMID:19513748 RGD:13838804, RGD:13838840 NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 severity IEP mRNA:increased expression:pancreas (human) RGD PMID:27919956 RGD:13451128 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK10 mitogen-activated protein kinase 10 severity IAGP DNA:SNP:intron: (rs2589506) (human) RGD PMID: RGD:13838853 NCBI chr 4:86,010,405...86,594,074
Ensembl chr 4:85,990,007...86,594,625 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 exacerbates IEP protein:increased phosphorylation:pancreas (human) RGD PMID:24395444 RGD:150340683 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 IDA RGD PMID:22517435 RGD:14348976 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 severity IEP mRNA:increased expression:pancreas (human) RGD PMID:27919956 RGD:13451128 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G PALLD palladin, cytoskeletal associated protein IAGP ClinVar Annotator: match by term: Pancreatic adenocarcinoma ClinVar PMID:9536098 PMID:10454945 PMID:11474289 PMID:17194196 PMID:17415588 More... NCBI chr 4:168,497,052...168,928,441
Ensembl chr 4:168,497,052...168,928,457 		JBrowse link
G PLAT plasminogen activator, tissue type IEP mRNA:increased expression:pancreas (human) RGD PMID:16733850 RGD:11541045 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709 		JBrowse link
G RAC1 Rac family small GTPase 1 treatment IMP human cells in a mouse model RGD PMID:21037555 RGD:14392805 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967 		JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase treatment IMP human cells in a mouse model RGD PMID:15014358 RGD:14392893 NCBI chr 3:12,583,601...12,664,117
Ensembl chr 3:12,582,101...12,664,201 		JBrowse link
G RALB RAS like proto-oncogene B treatment IMP human cells in a mouse model RGD PMID:17174914 RGD:14394417 NCBI chr 2:120,240,070...120,294,710
Ensembl chr 2:120,240,064...120,294,710 		JBrowse link
G RALBP1 ralA binding protein 1 treatment IMP human cells in a mouse model RGD PMID:22509328 RGD:13792559 NCBI chr18:9,475,009...9,538,114
Ensembl chr18:9,475,009...9,538,114 		JBrowse link
G SMAD7 SMAD family member 7 severity IMP human cell and construct in a mouse model RGD PMID:10498890 RGD:14394510 NCBI chr18:48,919,853...48,950,965
Ensembl chr18:48,919,853...48,950,965 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 ameliorates HEP protein:increased expression:pancreas (human) RGD PMID:24658320 RGD:155630608 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960 		JBrowse link
G VEGFC vascular endothelial growth factor C exacerbates IEP protein:increased expression:pancreas (human) RGD PMID:22082308 RGD:155630643 NCBI chr 4:176,683,538...176,792,922
Ensembl chr 4:176,683,538...176,792,922 		JBrowse link
pancreatic adenosquamous carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TGFB2 transforming growth factor beta 2 ameliorates IMP human cells in a mouse model RGD PMID:21366804 RGD:155630611 NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619 		JBrowse link
pancreatic cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A4GNT alpha-1,4-N-acetylglucosaminyltransferase IEP mRNA:increased expression:blood, mononuclear cell RGD PMID:16441422 RGD:2325199 NCBI chr 3:138,123,713...138,133,302
Ensembl chr 3:138,123,713...138,132,390 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 IEP mRNA, protein:increased expression:pancreas RGD PMID:19020751 RGD:2317509 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 severity IEP mRNA:increased expression:pancreas RGD PMID:15688370 RGD:2325200 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253 		JBrowse link
G ABCC5 ATP binding cassette subfamily C member 5 IEP mRNA:increased expression:pancreas RGD PMID:15688370 RGD:2325200 NCBI chr 3:183,919,934...184,017,884
Ensembl chr 3:183,919,934...184,017,939 		JBrowse link
G ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase IAGP
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19648918 PMID:26098869 PMID:20103627 RGD:2317511 NCBI chr 9:133,250,401...133,275,201
Ensembl chr 9:133,233,278...133,276,024 		JBrowse link
G ACE angiotensin I converting enzyme ISO RGD PMID:19880966 RGD:2325208 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ACVR1 activin A receptor type 1 IEP RGD PMID:9714055 RGD:2317217 NCBI chr 2:157,736,446...157,876,330
Ensembl chr 2:157,736,251...157,876,330 		JBrowse link
G ACVR1B activin A receptor type 1B IAGP
EXP
IEP		 CTD Direct Evidence: marker/mechanism
mRNA:increased expression:pancreas		 CTD
OMIM
RGD		 PMID:11248065 PMID:9714055 RGD:1598735, RGD:2317217 NCBI chr12:51,951,699...51,997,078
Ensembl chr12:51,951,699...51,997,078 		JBrowse link
G ACVR2A activin A receptor type 2A IEP RGD PMID:9714055 RGD:2317217 NCBI chr 2:147,844,517...147,930,822
Ensembl chr 2:147,844,517...147,930,826 		JBrowse link
G ADAM15 ADAM metallopeptidase domain 15 IEP mRNA:increased expression:pancreas, epithelial cell RGD PMID:17465204 RGD:2325247 NCBI chr 1:155,051,316...155,062,775
Ensembl chr 1:155,050,566...155,062,775 		JBrowse link
G ADAM9 ADAM metallopeptidase domain 9 IEP mRNA:increased expression:pancreas, epithelial cell RGD PMID:17465204 RGD:2325247 NCBI chr 8:38,996,973...39,105,261
Ensembl chr 8:38,996,754...39,105,445 		JBrowse link
G ADGRE5 adhesion G protein-coupled receptor E5 IEP protein:increased expression:pancreas RGD PMID:12428789 RGD:2317573 NCBI chr19:14,381,444...14,408,723
Ensembl chr19:14,380,501...14,408,725 		JBrowse link
G ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide IAGP DNA:polymorphism: :p.R272Q (human) RGD PMID:19068087 RGD:2325313 NCBI chr 4:99,336,497...99,352,746
Ensembl chr 4:99,336,497...99,352,746 		JBrowse link
G ADM adrenomedullin disease_progression IMP RGD PMID:16841081 PMID:17363587 RGD:2325318, RGD:2325317 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397 		JBrowse link
G AGER advanced glycosylation end-product specific receptor IEP protein:decreased expression:serum RGD PMID:20398646 RGD:2325643 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322 		JBrowse link
G AGTR2 angiotensin II receptor type 2 IEP mRNA:increased expression:pancreas RGD PMID:11916627 RGD:2325641 NCBI chr  X:116,170,744...116,174,974
Ensembl chr  X:116,170,744...116,174,974 		JBrowse link
G AHR aryl hydrocarbon receptor IEP
EXP		 mRNA:increased expression:pancreas
CTD Direct Evidence: marker/mechanism|therapeutic		 CTD
RGD		 PMID:12203118 PMID:25826687 PMID:12203118 RGD:2325664 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 severity
treatment		 IEP
IDA		 protein:increased phosphorylation:pancreas (human)
human cells in a mouse model		 RGD PMID:20697673 PMID:11595724 RGD:13450953, RGD:13452388 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G AKT2 AKT serine/threonine kinase 2 TAS RGD PMID:16847462 PMID:19506583 RGD:2290476, RGD:5490965 NCBI chr19:40,230,317...40,285,345
Ensembl chr19:40,230,317...40,285,536 		JBrowse link
G ALB albumin disease_progression IEP RGD PMID:18154768 PMID:20508721 RGD:2325678, RGD:2325675 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 IEP protein:decreased expression:pancreas RGD PMID:19216797 RGD:2325688 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442 		JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member susceptibility IAGP DNA:polymorphism (human)
DNA:polymorphism: :p.E504K (human)		 RGD PMID:15714130 PMID:19068087 RGD:2325694, RGD:2325313 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type EXP CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr17:8,072,636...8,087,716
Ensembl chr17:8,072,636...8,087,716 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase IEP
EXP
IMP		 protein:increased expression:pancreas
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:30258081 PMID:12163367 PMID:12481414 RGD:2317524, RGD:2317523 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119 		JBrowse link
G ANG angiogenin disease_progression IEP mRNA, protein:increased expression:pancreas, serum RGD PMID:8665497 RGD:2325716 NCBI chr14:20,684,177...20,694,186
Ensembl chr14:20,684,177...20,698,971 		JBrowse link
G ANXA1 annexin A1 IMP
IEP		 protein:increased expression:pancreas RGD PMID:19173988 PMID:17974280 RGD:2325722, RGD:2325723 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,629 		JBrowse link
G ANXA10 annexin A10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28369074 NCBI chr 4:168,092,537...168,187,736
Ensembl chr 4:168,092,537...168,187,736 		JBrowse link
G APAF1 apoptotic peptidase activating factor 1 IEP mRNA:increased expression:pancreas RGD PMID:17224646 RGD:2325739 NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,149...98,735,433 		JBrowse link
G APC APC regulator of WNT signaling pathway IAGP
ISO		 DNA:deletions (human)
ClinVar Annotator: match by term: Cancer of the pancreas
DNA:mutation, loss of heterozygosity		 ClinVar
RGD		 PMID:1316610 PMID:8381579 PMID:9101302 PMID:9824584 PMID:11852337 More... RGD:2317208, RGD:2317207 NCBI chr 5:112,707,498...112,846,239
Ensembl chr 5:112,707,518...112,846,239 		JBrowse link
G APOA1 apolipoprotein A1 IEP protein:decreased expression:serum
protein:increased expression:pancreas		 RGD PMID:17312459 PMID:17332923 RGD:2325758, RGD:2325757 NCBI chr11:116,835,751...116,837,622
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G APOE apolipoprotein E IEP protein:increased expression:pancreas (human) RGD PMID:16215274 RGD:2317552 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G ARID1A AT-rich interaction domain 1A TAS RGD PMID:23355908 RGD:8694154 NCBI chr 1:26,696,015...26,782,104
Ensembl chr 1:26,693,236...26,782,104 		JBrowse link
G ARID1B AT-rich interaction domain 1B TAS RGD PMID:23355908 RGD:8694154 NCBI chr 6:156,776,026...157,210,779
Ensembl chr 6:156,776,020...157,210,779 		JBrowse link
G ARPC1A actin related protein 2/3 complex subunit 1A IAGP DNA:amplification (human) RGD PMID:19145645 RGD:2317557 NCBI chr 7:99,325,898...99,366,262
Ensembl chr 7:99,325,898...99,366,262 		JBrowse link
G ARTN artemin disease_progression IEP mRNA:increased expression:pancreas RGD PMID:19304517 PMID:20395845 RGD:2325817, RGD:2325815 NCBI chr 1:43,933,801...43,937,240
Ensembl chr 1:43,933,320...43,937,240 		JBrowse link
G ATM ATM serine/threonine kinase susceptibility IAGP
EXP		 DNA:SNP:intron:rs664677 (human)
ClinVar Annotator: match by term: Pancreatic cancer
CTD Direct Evidence: marker/mechanism
DNA:SNP:exon:rs1801516(human)
DNA:SNP: :60G>A(human)		 ClinVar
CTD
RGD		 PMID:8698354 PMID:8845835 PMID:9497252 PMID:9536098 PMID:9792409 More... RGD:2317367, RGD:2317363, RGD:2317234 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102 		JBrowse link
G ATR ATR serine/threonine kinase IAGP DNA:SNP: :340C>T (human) RGD PMID:18381943 RGD:2317234 NCBI chr 3:142,449,235...142,578,733
Ensembl chr 3:142,449,007...142,578,733 		JBrowse link
G ATRX ATRX chromatin remodeler EXP CTD Direct Evidence: marker/mechanism CTD PMID:21252315 NCBI chr  X:77,504,880...77,786,216
Ensembl chr  X:77,504,880...77,786,233 		JBrowse link
G AXL AXL receptor tyrosine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:26206560 NCBI chr19:41,219,223...41,261,766
Ensembl chr19:41,219,223...41,261,766 		JBrowse link
G B3GALT5 beta-1,3-galactosyltransferase 5 IEP mRNA:increased expression:pancreas RGD PMID:14555842 RGD:2317558 NCBI chr21:39,612,940...39,673,137
Ensembl chr21:39,556,442...39,673,137 		JBrowse link
G BAD BCL2 associated agonist of cell death treatment IDA human cells in a mouse model RGD PMID:23523869 RGD:13451129 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704 		JBrowse link
G BAG3 BAG cochaperone 3 IEP mRNA:increased expression:pancreas RGD PMID:11513873 RGD:2325843 NCBI chr10:119,651,380...119,677,819
Ensembl chr10:119,651,380...119,677,819 		JBrowse link
G BAG4 BAG cochaperone 4 IEP mRNA:increased expression:pancreas RGD PMID:10799310 RGD:2325852 NCBI chr 8:38,176,855...38,213,301
Ensembl chr 8:38,176,533...38,213,301 		JBrowse link
G BAP1 BRCA1 associated deubiquitinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25231345 NCBI chr 3:52,401,008...52,410,008
Ensembl chr 3:52,401,008...52,410,008 		JBrowse link
G BCAR1 BCAR1 scaffold protein, Cas family member EXP CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr16:75,228,181...75,268,007
Ensembl chr16:75,228,181...75,268,053 		JBrowse link
G BCL2L1 BCL2 like 1 severity IMP
EXP		 human gene in a mouse model
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16904634 PMID:17941720 RGD:11353794 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BID BH3 interacting domain death agonist IDA RGD PMID:15943879 RGD:2317560 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770 		JBrowse link
G BOC BOC cell adhesion associated, oncogene regulated TAS RGD PMID:18772397 RGD:5490966 NCBI chr 3:113,210,926...113,287,459
Ensembl chr 3:113,211,003...113,287,459 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase disease_progression ISO
IMP		 human gene in a mouse model RGD PMID:18490924 PMID:22628411 PMID:22871572 RGD:13451537, RGD:13462040, RGD:13461863 NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929 		JBrowse link
G BRCA1 BRCA1 DNA repair associated EXP
IAGP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 4
ClinVar Annotator: match by term: Pancreatic cancer
ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 4
ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 2		 CTD
OMIM
ClinVar		 PMID:1157798 PMID:2173504 PMID:2316185 PMID:2504116 PMID:2618727 More... NCBI chr17:43,044,295...43,170,327
Ensembl chr17:43,044,295...43,170,245 		JBrowse link
G BRCA2 BRCA2 DNA repair associated susceptibility IAGP
EXP		 DNA:mutations: :
ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 2
ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 2
ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 2 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 2
ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 4
ClinVar Annotator: match by term: Pancreatic cancer | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 2
CTD Direct Evidence: marker/mechanism		 ClinVar
OMIM
CTD
RGD		 PMID:186727 PMID:251866 PMID:278235 PMID:1772447 PMID:2200631 More... RGD:9068467 NCBI chr13:32,315,077...32,400,268
Ensembl chr13:32,315,086...32,400,268 		JBrowse link
G BSG basigin (Ok blood group) EXP CTD Direct Evidence: marker/mechanism CTD PMID:36574092 NCBI chr19:571,283...583,493
Ensembl chr19:571,277...583,494 		JBrowse link
G BUB1B BUB1 mitotic checkpoint serine/threonine kinase B IEP protein:altered localization:pancreas RGD PMID:17242465 RGD:2326105 NCBI chr15:40,161,069...40,221,123
Ensembl chr15:40,161,023...40,221,123 		JBrowse link
G CAB39 calcium binding protein 39 disease_progression IEP RGD PMID:28197410 RGD:14398834 NCBI chr 2:230,712,842...230,821,075
Ensembl chr 2:230,712,842...230,821,075 		JBrowse link
G CACYBP calcyclin binding protein disease_progression IEP mRNA, protein:increased expression:pancreas RGD PMID:18765951 RGD:2326146 NCBI chr 1:174,999,435...175,012,027
Ensembl chr 1:174,999,163...175,012,027 		JBrowse link
G CAP1 cyclase associated actin cytoskeleton regulatory protein 1 disease_progression IEP mRNA, protein:increased expression:pancreas RGD PMID:19188911 RGD:2326238 NCBI chr 1:40,040,240...40,072,648
Ensembl chr 1:40,040,233...40,072,649 		JBrowse link
G CAPN10 calpain 10 susceptibility IAGP DNA:SNP:intron:rs3792267 (human) RGD PMID:20178008 RGD:4107073 NCBI chr 2:240,586,734...240,599,104
Ensembl chr 2:240,586,734...240,617,705 		JBrowse link
G CASP8 caspase 8 susceptibility IAGP DNA:deletion, insertion:promoter (human)
DNA:SNP: :rs1045485 (human)		 RGD PMID:18483392 PMID:19843670 RGD:2315744, RGD:2317230 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CASP9 caspase 9 susceptibility
treatment		 IAGP
IDA		 DNA:snp:promoter:g.-1263A>G (human) RGD PMID:20357690 PMID:19209030 RGD:13451540, RGD:13462046 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CAT catalase disease_progression IEP protein:decreased expression:pancreas RGD PMID:12499913 RGD:2317410 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CBR4 carbonyl reductase 4 IAGP ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 1 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 4
ClinVar Annotator: match by term: PALLD-related condition | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 1		 ClinVar PMID:25741868 PMID:28492532 NCBI chr 4:168,894,486...169,010,255
Ensembl chr 4:168,863,770...169,010,275 		JBrowse link
G CCAT1 colon cancer associated transcript 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26752646 NCBI chr 8:127,207,382...127,219,268 JBrowse link
G CCKAR cholecystokinin A receptor ISO
IEP		 mRNA:increased expression:pancreas RGD PMID:8222074 PMID:10457335 RGD:4110822, RGD:4110817 NCBI chr 4:26,481,396...26,490,484
Ensembl chr 4:26,481,396...26,490,484 		JBrowse link
G CCKBR cholecystokinin B receptor disease_progression
susceptibility		 ISO
IMP		 mRNA:increased expression:pancreas RGD PMID:8222074 PMID:8302799 PMID:15688412 PMID:1458479 RGD:4110822, RGD:4110823, RGD:4110829, RGD:4110821 NCBI chr11:6,259,838...6,272,127
Ensembl chr11:6,259,806...6,272,127 		JBrowse link
G CCL20 C-C motif chemokine ligand 20 IEP
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:30603057 PMID:10225458 RGD:7483623 NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO RGD PMID:19155524 RGD:2317567 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCND1 cyclin D1 disease_progression
treatment		 IMP
ISO
IDA		 human cells in a mouse model
mRNA, protein:increased expression:pancreas (mouse)		 RGD PMID:22722256 PMID:11159909 PMID:17541034 RGD:13451541, RGD:13452385, RGD:13462059 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CCNG1 cyclin G1 treatment IMP human cells in mouse model RGD PMID:11177556 RGD:151361109 NCBI chr 5:163,437,571...163,457,640
Ensembl chr 5:163,437,569...163,448,199 		JBrowse link
G CCR4 C-C motif chemokine receptor 4 IEP protein:increased expression:pancreas RGD PMID:12761880 RGD:2317610 NCBI chr 3:32,951,644...32,956,349
Ensembl chr 3:32,951,644...32,957,120 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 ISO RGD PMID:19155524 RGD:2317567 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206 		JBrowse link
G CD24 CD24 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:28369074 NCBI chr 6:106,969,831...106,976,855
Ensembl chr 6:106,969,831...106,975,627 		JBrowse link
G CD44 CD44 molecule (IN blood group) EXP CTD Direct Evidence: marker/mechanism CTD PMID:17446842 NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402 		JBrowse link
G CDC42 cell division cycle 42 severity IEP mRNA, protein:increased expression:pancreas (human) RGD PMID:28181096 RGD:13452244 NCBI chr 1:22,052,709...22,101,360
Ensembl chr 1:22,052,627...22,101,360 		JBrowse link
G CDH1 cadherin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18223216 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537 		JBrowse link
G CDK4 cyclin dependent kinase 4 susceptibility
disease_progression		 IEP
ISO		 protein:increased expression:islet of Langerhans (human)
protein:increased expression:islet of Langerhans, nucleus (rat)
protein:increased expression:pancreas (mouse)		 RGD PMID:22761470 PMID:24531709 PMID:22477723 PMID:11159909 RGD:13452384, RGD:13452387, RGD:13452386, RGD:13452385 NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A IAGP
EXP		 DNA:mutations:exon
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:10627132 PMID:26098869 PMID:18772397 RGD:5490966 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:20876774 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687 		JBrowse link
G CFTR CF transmembrane conductance regulator no_association
onset		 IAGP RGD PMID:17072959 PMID:16227367 RGD:2317157, RGD:2317156 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971 		JBrowse link
G CHEK1 checkpoint kinase 1 disease_progression IAGP DNA:SNP: :35G>A (human) RGD PMID:18381943 RGD:2317234 NCBI chr11:125,625,136...125,681,124
Ensembl chr11:125,625,163...125,676,255 		JBrowse link
G CLDN4 claudin 4 IEP
IMP		 RGD PMID:19793693 PMID:19555390 RGD:2317580, RGD:2317583 NCBI chr 7:73,830,996...73,832,690
Ensembl chr 7:73,799,542...73,832,690 		JBrowse link
G CLPTM1 CLPTM1 regulator of GABA type A receptor forward trafficking EXP CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr19:44,954,585...44,993,341
Ensembl chr19:44,954,585...44,993,341 		JBrowse link
G CNR1 cannabinoid receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16818650 NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,347 		JBrowse link
G CNR2 cannabinoid receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16818650 NCBI chr 1:23,870,515...23,913,362
Ensembl chr 1:23,870,515...23,913,362 		JBrowse link
G CTNNB1 catenin beta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18223216 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18307536 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYCS cytochrome c, somatic IDA RGD PMID:11920648 RGD:2317614 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260 		JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 susceptibility IAGP DNA:transition:5' utr:-34T>C rs743572 (human) RGD PMID:19642097 RGD:2317618 NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472 		JBrowse link
G DAXX death domain associated protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:21252315 NCBI chr 6:33,318,558...33,322,959
Ensembl chr 6:33,318,558...33,323,016 		JBrowse link
G DDR1 discoidin domain receptor tyrosine kinase 1 treatment ISO RGD PMID:31310125 RGD:151347425 NCBI chr 6:30,880,970...30,900,156
Ensembl chr 6:30,876,421...30,900,156 		JBrowse link
G DPYD dihydropyrimidine dehydrogenase disease_progression IEP
EXP
IMP		 protein:increased expression:pancreas
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:17443278 PMID:19020767 PMID:20072795 PMID:18309485 RGD:2317629, RGD:2317630 NCBI chr 1:97,077,743...97,921,059
Ensembl chr 1:97,077,743...97,995,000 		JBrowse link
G DYRK1A dual specificity tyrosine phosphorylation regulated kinase 1A EXP CTD Direct Evidence: marker/mechanism CTD PMID:31838052 NCBI chr21:37,365,573...37,526,358
Ensembl chr21:37,365,573...37,526,358 		JBrowse link
G E2F1 E2F transcription factor 1 treatment ISO RGD PMID:28344092 RGD:13838737 NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385 		JBrowse link
G EFEMP1 EGF containing fibulin extracellular matrix protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19208748 NCBI chr 2:55,865,967...55,923,782
Ensembl chr 2:55,865,967...55,924,139 		JBrowse link
G EGF epidermal growth factor disease_progression IEP
TAS		 protein:increased expression:pancreas RGD PMID:1347773 PMID:19506583 RGD:2317650, RGD:5490965 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G EGFR epidermal growth factor receptor IMP
EXP
TAS		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:27720938 PMID:17452677 PMID:19506583 RGD:5131631, RGD:5490965 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EIF4A3 eukaryotic translation initiation factor 4A3 IEP protein:increased expression:serum (human) RGD PMID:15796914 RGD:10045549 NCBI chr17:80,134,369...80,147,128
Ensembl chr17:80,134,369...80,147,151 		JBrowse link
G EPCAM epithelial cell adhesion molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:17446842 NCBI chr 2:47,369,311...47,387,020
Ensembl chr 2:47,345,158...47,387,601 		JBrowse link
G EPHA3 EPH receptor A3 IDA RGD PMID:14670182 RGD:2317720 NCBI chr 3:89,107,621...89,482,134
Ensembl chr 3:89,107,621...89,482,134 		JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit susceptibility IAGP DNA:snp:3' utr:c.*197G>T (rs3212986) (human) RGD PMID:27050953 RGD:13207426 NCBI chr19:45,407,334...45,451,547
Ensembl chr19:45,407,334...45,478,828 		JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit treatment IAGP
IDA		 pancreatic adenocarcinoma;DNA:SNPs: :rs1799793,rs1052555(human)
DNA,protein:SNPs:exons:rs1799793,rs1052559		 RGD PMID:18544627 PMID:21404106 PMID:16458430 RGD:2317223, RGD:11252206, RGD:2317228 NCBI chr19:45,349,837...45,370,573
Ensembl chr19:45,349,837...45,370,918 		JBrowse link
G ERCC4 ERCC excision repair 4, endonuclease catalytic subunit IAGP pancreatic adenocarcinoma;DNA:SNP: :rs1800067(human) RGD PMID:18544627 RGD:2317223 NCBI chr16:13,920,154...13,952,348
Ensembl chr16:13,920,138...13,952,348 		JBrowse link
G ETAA1 ETAA1 activator of ATR kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr 2:67,397,333...67,412,089
Ensembl chr 2:67,397,322...67,412,089 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO protein:increased expression:pancreas RGD PMID:22222375 RGD:9588324 NCBI chr 7:148,807,383...148,884,291
Ensembl chr 7:148,807,257...148,884,321 		JBrowse link
G FANCA FA complementation group A IAGP DNA,Protein:polymorphisms:exons:c.377C>G, c.661A>G (human) RGD PMID:15591268 RGD:2317735 NCBI chr16:89,737,549...89,816,647
Ensembl chr16:89,726,683...89,816,977 		JBrowse link
G FANCC FA complementation group C IDA
IAGP		 DNA:nonsense mutation (human) RGD PMID:16243825 PMID:15695377 RGD:2317238, RGD:2317239 NCBI chr 9:95,099,054...95,317,709
Ensembl chr 9:95,099,054...95,426,796 		JBrowse link
G FANCG FA complementation group G IDA RGD PMID:16243825 RGD:2317238 NCBI chr 9:35,073,839...35,079,942
Ensembl chr 9:35,073,835...35,080,004 		JBrowse link
G FASLG Fas ligand resistance
severity		 IDA
IAGP
IEP		 DNA:polymorphism:promoter:-844>>T (human) RGD PMID:11115536 PMID:18483392 PMID:12370548 RGD:2317745, RGD:2315744, RGD:2317744 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G FGF13 fibroblast growth factor 13 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19917848 NCBI chr  X:138,614,727...139,205,023
Ensembl chr  X:138,614,727...139,222,777 		JBrowse link
G FGF2 fibroblast growth factor 2 severity IDA
IEP		 protein:increased expression:bile
mRNA:increased expression:pancreas 		RGD PMID:12670449 PMID:11478488 PMID:11562741 PMID:9293890 RGD:2317759, RGD:2317765, RGD:2317760, RGD:2317762 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236 		JBrowse link
G FLT3LG fms related receptor tyrosine kinase 3 ligand ISO RGD PMID:16528542 RGD:11049499 NCBI chr19:49,474,215...49,486,231
Ensembl chr19:49,474,207...49,486,231 		JBrowse link
G FOXP1 forkhead box P1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25485836 NCBI chr 3:70,954,708...71,583,978
Ensembl chr 3:70,954,693...71,583,978 		JBrowse link
G FSCN1 fascin actin-bundling protein 1 severity IEP protein:increased expression:pancreas RGD PMID:17696949 RGD:2317785 NCBI chr 7:5,592,816...5,606,655
Ensembl chr 7:5,592,816...5,606,655 		JBrowse link
G FXYD3 FXYD domain containing ion transport regulator 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16003754 NCBI chr19:35,115,823...35,124,324
Ensembl chr19:35,115,823...35,124,324 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha EXP CTD Direct Evidence: therapeutic CTD PMID:19003803 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334 		JBrowse link
G GAGE1 G antigen 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:14991579 NCBI chr  X:49,599,013...49,608,538
Ensembl chr  X:49,599,020...49,608,538 		JBrowse link
G GDNF glial cell derived neurotrophic factor severity IEP RGD PMID:18652760 RGD:2324925 NCBI chr 5:37,812,677...37,840,041
Ensembl chr 5:37,812,677...37,840,041 		JBrowse link
G GLI1 GLI family zinc finger 1 TAS RGD PMID:21186299 PMID:18772397 RGD:5491005, RGD:5490966 NCBI chr12:57,459,785...57,472,268
Ensembl chr12:57,459,785...57,472,268 		JBrowse link
G GLI3 GLI family zinc finger 3 TAS RGD PMID:18772397 RGD:5490966 NCBI chr 7:41,960,949...42,264,268
Ensembl chr 7:41,960,949...42,264,100 		JBrowse link
G GNAS GNAS complex locus IEP RGD PMID:12771991 RGD:2317256 NCBI chr20:58,839,748...58,911,192
Ensembl chr20:58,839,718...58,911,192 		JBrowse link
G GOLM1 golgi membrane protein 1 HEP RGD PMID:37338014 RGD:401827117 NCBI chr 9:86,026,146...86,100,149
Ensembl chr 9:86,026,146...86,100,173 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 susceptibility IAGP
IDA		 DNA:SNP:cds:p.I105V (rs1695) (human) RGD PMID:19786118 PMID:19536452 RGD:2317804, RGD:2317805 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G HGF hepatocyte growth factor IEP protein:increased expression:serum RGD PMID:20017454 RGD:2317895 NCBI chr 7:81,699,010...81,770,047
Ensembl chr 7:81,699,010...81,770,438 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:16628086 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HS3ST2 heparan sulfate-glucosamine 3-sulfotransferase 2 IDA DNA:hypermethylation:promoter (human) RGD PMID:12527896 RGD:2317633 NCBI chr16:22,814,162...22,916,338
Ensembl chr16:22,814,162...22,916,338 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 disease_progression IDA RGD PMID:21833720 RGD:10402768 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,305,813 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 IEP mRNA, protein:increased expression:pancreas RGD PMID:11815996 RGD:2325165 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IFNA1 interferon alpha 1 EXP CTD Direct Evidence: therapeutic CTD PMID:17198089 PMID:17961653 NCBI chr 9:21,440,439...21,441,316
Ensembl chr 9:21,440,439...21,441,316 		JBrowse link
G IFNA2 interferon alpha 2 EXP CTD Direct Evidence: therapeutic CTD PMID:12738744 NCBI chr 9:21,384,255...21,385,398
Ensembl chr 9:21,384,255...21,385,398 		JBrowse link
G IFNA5 interferon alpha 5 EXP CTD Direct Evidence: therapeutic CTD PMID:15320962 NCBI chr 9:21,304,326...21,305,313
Ensembl chr 9:21,304,326...21,305,313 		JBrowse link
G IFNG interferon gamma IEP protein:increased expression:plasma RGD PMID:19152246 RGD:2317258 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IGF1 insulin like growth factor 1 susceptibility IAGP DNA:polymorphism (human) RGD PMID:19064563 RGD:2306689 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
G IGF1R insulin like growth factor 1 receptor IMP RGD PMID:19732452 PMID:19885860 PMID:14559833 RGD:2317642, RGD:2317640, RGD:2317651 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530 		JBrowse link
G IL10 interleukin 10 susceptibility
disease_progression		 IAGP
IEP		 DNA:polymorphism: :-1082G>A (human)
protein:increased expression:serum		 RGD PMID:19250218 PMID:30304975 PMID:30610790 PMID:17235586 RGD:2317653, RGD:14975257, RGD:14975253, RGD:2317655 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL13 interleukin 13 disease_progression IEP
IMP		 protein:increased expression:pancreas RGD PMID:18758789 PMID:12808442 RGD:2317669, RGD:2317670 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 treatment IMP RGD PMID:11748276 RGD:8549514 NCBI chr  X:115,003,982...115,017,616
Ensembl chr  X:115,003,975...115,019,977 		JBrowse link
G IL1A interleukin 1 alpha IEP RGD PMID:7787209 RGD:2311069 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta susceptibility IAGP
IEP		 DNA:polymorphisms:promoter:-511C>T, -31T>C (human)
protein:increased expression:serum (human)		 RGD PMID:19251436 PMID:7787209 RGD:2317215, RGD:2311069 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL2 interleukin 2 treatment IDA RGD PMID:9080118 RGD:8663440 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL24 interleukin 24 EXP CTD Direct Evidence: therapeutic CTD PMID:15580305 NCBI chr 1:206,897,443...206,904,139
Ensembl chr 1:206,897,443...206,904,139 		JBrowse link
G IL3 interleukin 3 IEP protein:increased expression:serum RGD PMID:15843207 RGD:2317663 NCBI chr 5:132,060,655...132,063,204
Ensembl chr 5:132,060,655...132,063,204 		JBrowse link
G IL4 interleukin 4 disease_progression ISO
IMP
IEP		 protein:increased expression:blood RGD PMID:10404069 PMID:12097255 PMID:19957810 RGD:2317267, RGD:2317265, RGD:2317261 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL4R interleukin 4 receptor disease_progression IEP protein:increased expression:pancreas RGD PMID:18758789 RGD:2317669 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778 		JBrowse link
G IL6 interleukin 6 disease_progression IEP RGD PMID:30610790 PMID:30304975 RGD:14975253, RGD:14975257 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G ILK integrin linked kinase IAGP
TAS		 DNA:mutations:exon RGD PMID:18772397 PMID:18772397 RGD:5490966, RGD:5490966 NCBI chr11:6,603,774...6,610,870
Ensembl chr11:6,603,708...6,610,874 		JBrowse link
G INPP4B inositol polyphosphate-4-phosphatase type II B EXP CTD Direct Evidence: marker/mechanism CTD PMID:29415082 NCBI chr 4:142,023,160...142,846,535
Ensembl chr 4:142,023,160...142,847,432 		JBrowse link
G INS insulin susceptibility
disease_progression		 IDA
IAGP
ISO		 associated with Diabetes Mellitus
DNA:Polymorphism:promoter:-23 HphI (human)
associated with Diabetes Mellitus, Non-Insulin-Depend		 RGD PMID:19375425 PMID:19152242 PMID:19572116 PMID:19628082 RGD:2317250, RGD:2317253, RGD:2317247, RGD:2317245 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221 		JBrowse link
G ITGA11 integrin subunit alpha 11 IAGP DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr15:68,296,532...68,432,163
Ensembl chr15:68,296,532...68,432,163 		JBrowse link
G ITGA4 integrin subunit alpha 4 IAGP DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr 2:181,457,205...181,538,940
Ensembl chr 2:181,457,202...181,538,940 		JBrowse link
G ITGA9 integrin subunit alpha 9 IAGP DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr 3:37,452,141...37,823,507
Ensembl chr 3:37,452,115...37,823,507 		JBrowse link
G KDR kinase insert domain receptor IDA
EXP		 CTD Direct Evidence: therapeutic CTD
RGD		 PMID:12385004 PMID:19930156 RGD:5684397 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595 		JBrowse link
G KLF5 KLF transcription factor 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr13:73,054,976...73,077,538
Ensembl chr13:73,054,976...73,077,541 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase disease_progression IDA
EXP
IAGP
TAS		 CTD Direct Evidence: marker/mechanism
DNA:mutations:exon		 CTD
OMIM
RGD		 PMID:14520703 PMID:19424582 PMID:21699781 PMID:24694877 PMID:25961927 More... RGD:1581761, RGD:5490965, RGD:5490966 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936 		JBrowse link
G L1CAM L1 cell adhesion molecule treatment IMP RGD PMID:22095073 RGD:11570404 NCBI chr  X:153,861,514...153,886,173
Ensembl chr  X:153,861,514...153,886,173 		JBrowse link
G LDHA lactate dehydrogenase A EXP CTD Direct Evidence: marker/mechanism CTD PMID:29384525 NCBI chr11:18,394,563...18,408,425
Ensembl chr11:18,394,560...18,408,425 		JBrowse link
G LIG3 DNA ligase 3 resistance IAGP DNA:SNP:intron:rs 2074522 (human) RGD PMID:19147782 RGD:2317363 NCBI chr17:34,980,512...35,010,872
Ensembl chr17:34,980,512...35,009,743 		JBrowse link
G LIG4 DNA ligase 4 susceptibility IAGP associated with Diabetes Mellitus;DNA:polymorphism: :54C>T (human) RGD PMID:19147782 RGD:2317363 NCBI chr13:108,207,442...108,218,349
Ensembl chr13:108,207,439...108,218,368 		JBrowse link
G LINC00673 long intergenic non-protein coding RNA 673 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27213290 NCBI chr17:72,403,322...72,592,804
Ensembl chr17:72,221,072...72,640,472 		JBrowse link
G LOC126862571 BRD4-independent group 4 enhancer GRCh37_chr17:41243136-41244335 IAGP ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 4
ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 4		 ClinVar PMID:7894492 PMID:7894493 PMID:8531967 PMID:8571953 PMID:9150148 More... NCBI chr17:43,091,119...43,092,318 JBrowse link
G LRP2 LDL receptor related protein 2 TAS RGD PMID:18772397 RGD:5490966 NCBI chr 2:169,127,109...169,362,534
Ensembl chr 2:169,127,109...169,362,534 		JBrowse link
G LUM lumican disease_progression IAGP
IEP		 DNA:SNP: :rs2268578 (human) RGD PMID:19843670 PMID:17671699 RGD:2317230, RGD:2317682 NCBI chr12:91,102,629...91,111,494
Ensembl chr12:91,102,629...91,111,494 		JBrowse link
G LY6E lymphocyte antigen 6 family member E EXP CTD Direct Evidence: marker/mechanism CTD PMID:17446842 NCBI chr 8:143,018,529...143,022,409
Ensembl chr 8:143,017,982...143,023,832 		JBrowse link
G MANF mesencephalic astrocyte derived neurotrophic factor no_association IAGP DNA:polymorphisms: :multiple (human)
DNA:point mutations, deletions:cds:multiple (human)		 RGD PMID:17072959 PMID:9174057 RGD:2317157, RGD:2325804 NCBI chr 3:51,385,291...51,389,397
Ensembl chr 3:51,385,291...51,389,397 		JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 IAGP DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr17:12,020,877...12,143,828
Ensembl chr17:12,020,829...12,143,830 		JBrowse link
G MEN1 menin 1 IDA
EXP		 associated with Neuroendocrine Tumors; protein:increased expression:multiple organs
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:17961653 PMID:21252315 PMID:17278096 RGD:2317340 NCBI chr11:64,803,516...64,811,294
Ensembl chr11:64,803,510...64,811,294 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase severity ISO
TAS
IEP		 protein:increased expression:pancreas (rat)
mRNA:increased expression:pancreas (human)		 RGD PMID:9211490 PMID:19506583 PMID:15448002 RGD:2317613, RGD:5490965, RGD:2317235 NCBI chr 7:116,672,196...116,798,377
Ensembl chr 7:116,672,196...116,798,377 		JBrowse link
G MGAT4A alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A IEP RGD PMID:16434023 RGD:2317701 NCBI chr 2:98,619,106...98,731,132
Ensembl chr 2:98,619,106...98,731,132 		JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase IEP protein:decreased expression:neuroendocrine tumor (human) RGD PMID:19118063 RGD:2317628 NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983 		JBrowse link
G MIR107 microRNA 107 severity IEP RGD PMID:28720759 RGD:14975279 NCBI chr10:89,592,747...89,592,827
Ensembl chr10:89,592,747...89,592,827 		JBrowse link
G MIR1179 microRNA 1179 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29859832 NCBI chr15:88,608,107...88,608,197
Ensembl chr15:88,608,107...88,608,197 		JBrowse link
G MKI67 marker of proliferation Ki-67 disease_progression IEP
IDA		 protein:increased expression:pancreas RGD PMID:20350215 PMID:20137856 RGD:2317703, RGD:2317704 NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423 		JBrowse link
G MMP2 matrix metallopeptidase 2 IEP
EXP		 protein:increased activity:pancreatic juice
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:pancreas		 CTD
RGD		 PMID:30603057 PMID:11961486 PMID:7635566 RGD:2325752, RGD:2325766 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP9 matrix metallopeptidase 9 disease_progression ISO
EXP
IEP		 CTD Direct Evidence: marker/mechanism
mRNA:increased expression:pancreas
protein:increased expression:serum		 CTD
RGD		 PMID:22952646 PMID:18445772 PMID:7635566 PMID:19629003 PMID:18030366 RGD:2325849, RGD:2325766, RGD:2325831, RGD:2325854 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MPO myeloperoxidase resistance IAGP DNA:polymorphism:promoter:-463G>A (human) RGD PMID:18205184 RGD:2317406 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G MSLN mesothelin IDA
EXP
IMP
IEP		 CTD Direct Evidence: marker/mechanism
associated with Pancreatic Disease; protein:increased expression:pancreas		 CTD
RGD		 PMID:11751476 PMID:19843662 PMID:18281514 PMID:17785569 PMID:17019794 RGD:2326052, RGD:2326056, RGD:2326062, RGD:2326060 NCBI chr16:760,734...768,865
Ensembl chr16:760,734...768,865 		JBrowse link
G MTAP methylthioadenosine phosphorylase IEP DNA, protein:deletion, decreased activity:pancreas: RGD PMID:15534104 RGD:2317952 NCBI chr 9:21,802,636...21,941,115
Ensembl chr 9:21,802,636...21,937,651 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase susceptibility IAGP DNA:polymorphism: :677C>T (human) RGD PMID:16737574 RGD:2317120 NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455 		JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO RGD PMID:23149918 RGD:10040959 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase susceptibility
no_association		 IAGP DNA:Polymorphism: :rs1805087 (human) RGD PMID:18843018 PMID:16737574 RGD:2317118, RGD:2317120 NCBI chr 1:236,795,281...236,903,981
Ensembl chr 1:236,795,260...236,921,278 		JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase susceptibility IAGP DNA:polymorphism: :66A>G (human)
DNA:SNPs:intron, exon:rs162049, p.H595Y (rs10380) (human)		 RGD PMID:18843018 PMID:18515090 RGD:2317118, RGD:2325772 NCBI chr 5:7,850,859...7,901,113
Ensembl chr 5:7,851,186...7,906,025 		JBrowse link
G MUC1 mucin 1, cell surface associated disease_progression IEP
IDA		 protein:increased expression:pancreas
protein:increased secretion:bile		 RGD PMID:14654947 PMID:18383873 PMID:18039393 PMID:19129927 PMID:19055478 More... RGD:2317984, RGD:2324637, RGD:2324639, RGD:2317987, RGD:2324622, RGD:2324635 NCBI chr 1:155,185,824...155,192,915
Ensembl chr 1:155,185,824...155,192,916 		JBrowse link
G MUC16 mucin 16, cell surface associated IEP protein:increased expression:serum RGD PMID:19377061 RGD:2325129 NCBI chr19:8,848,844...9,065,751
Ensembl chr19:8,848,844...9,010,390 		JBrowse link
G MUC4 mucin 4, cell surface associated disease_progression IEP
IMP		 protein:increased expression:pancreas
mRNA:increased expression:peripheral blood mononuclear cell
mRNA:increased expression:pancreas		 RGD PMID:20303649 PMID:16274046 PMID:17595659 PMID:11751498 PMID:17406026 RGD:2324914, RGD:2324931, RGD:2324922, RGD:2324891, RGD:2324923 NCBI chr 3:195,746,771...195,811,929
Ensembl chr 3:195,746,765...195,811,973 		JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming IEP protein:increased glycosylation:serum
protein:increased expression:pancreas		 RGD PMID:19377061 PMID:14654947 RGD:2325129, RGD:2317984 NCBI chr11:1,157,953...1,201,138
Ensembl chr11:1,157,953...1,201,138 		JBrowse link
G MUC6 mucin 6, oligomeric mucus/gel-forming (gene/pseudogene) IEP protein:increased expression: : RGD PMID:10209489 RGD:2325167 NCBI chr11:1,012,823...1,036,718
Ensembl chr11:1,012,823...1,036,718 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:25961927 PMID:22024988 RGD:7240699 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G NAP1L1 nucleosome assembly protein 1 like 1 IMP human gene in a mouse model RGD PMID:25071868 RGD:9590074 NCBI chr12:76,036,585...76,084,685
Ensembl chr12:76,036,585...76,084,735 		JBrowse link
G NAT1 N-acetyltransferase 1 susceptibility IAGP DNA:polymorphism (human)
DNA:polymorphisms,haplotype: :		 RGD PMID:18499698 PMID:18006927 PMID:18006927 RGD:2317168, RGD:2317170, RGD:2317170 NCBI chr 8:18,170,467...18,223,689
Ensembl chr 8:18,170,477...18,223,689 		JBrowse link
G NAT2 N-acetyltransferase 2 susceptibility IAGP DNA:polymorphism (human) RGD PMID:18027363 RGD:2317169 NCBI chr 8:18,386,301...18,401,218
Ensembl chr 8:18,391,282...18,401,218 		JBrowse link
G NCAM1 neural cell adhesion molecule 1 disease_progression
severity		 IEP
IDA		 RGD PMID:11249065 PMID:10374842 RGD:2326074, RGD:2326075 NCBI chr11:112,961,420...113,278,436
Ensembl chr11:112,961,275...113,278,436 		JBrowse link
G NFKBIA NFKB inhibitor alpha EXP CTD Direct Evidence: therapeutic CTD PMID:15861417 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NGFR nerve growth factor receptor severity IEP mRNA:increased expression:tumor:associated with longer overall survival RGD PMID:16704535 RGD:5508229 NCBI chr17:49,495,293...49,515,008
Ensembl chr17:49,495,293...49,515,008 		JBrowse link
G NOS2 nitric oxide synthase 2 disease_progression ISO
IEP		 protein:increased expression:pancreas RGD PMID:11196200 PMID:11687972 PMID:15165031 RGD:2325262, RGD:2325257, RGD:2325248 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOTCH1 notch receptor 1 disease_progression ISO protein:increased expression:pancreas RGD PMID:17297654 RGD:2325328 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048 		JBrowse link
G NR4A1 nuclear receptor subfamily 4 group A member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20660371 NCBI chr12:52,022,832...52,059,503
Ensembl chr12:52,022,832...52,059,507 		JBrowse link
G NR5A2 nuclear receptor subfamily 5 group A member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20101243 PMID:26098869 NCBI chr 1:200,027,710...200,177,415
Ensembl chr 1:200,027,614...200,177,420 		JBrowse link
G NRP1 neuropilin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15956974 NCBI chr10:33,177,493...33,334,667
Ensembl chr10:33,177,492...33,336,262 		JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 severity IEP mRNA:increased expression:tumor:associated with increased tumor aggressiveness RGD PMID:16704535 RGD:5508229 NCBI chr 1:156,815,750...156,881,850
Ensembl chr 1:156,815,636...156,881,850 		JBrowse link
G NUF2 NUF2 component of NDC80 kinetochore complex treatment IEP
IMP		 mRNA:increased expression:pancreas RGD PMID:26045769 PMID:25370920 RGD:11058437, RGD:28867232 NCBI chr 1:163,321,954...163,355,759
Ensembl chr 1:163,266,576...163,355,764 		JBrowse link
G OGG1 8-oxoguanine DNA glycosylase disease_progression IAGP DNA:polymorphism: :2657G>A (human)
DNA:polymorphism: :rs1052133 (human)		 RGD PMID:17230526 PMID:18559563 RGD:2317132, RGD:2317130 NCBI chr 3:9,749,952...9,783,108
Ensembl chr 3:9,749,944...9,788,219 		JBrowse link
G PALB2 partner and localizer of BRCA2 susceptibility IAGP
EXP		 DNA:nonsense mutations:exon:172_175del, 3116del, 3256C>T (human)
ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 3
ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 3
ClinVar Annotator: match by term: Pancreatic cancer 3
ClinVar Annotator: match by term: PANCREATIC CANCER, SUSCEPTIBILITY TO, 4
ClinVar Annotator: match by term: Pancreatic cancer 3 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 3
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD
RGD		 PMID:100849 PMID:9536098 PMID:17200668 PMID:17200671 PMID:17200672 More... RGD:2325776 NCBI chr16:23,603,165...23,641,310
Ensembl chr16:23,603,160...23,641,321 		JBrowse link
G PALLD palladin, cytoskeletal associated protein susceptibility IAGP
EXP
IEP		 DNA, mRNA:missense mutation, increased expression:pancreas:p.P239S (human)
ClinVar Annotator: match by term: PALLD-related condition
ClinVar Annotator: match by term: PALLD-related condition | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 1
ClinVar Annotator: match by term: PALLD-related condition | ClinVar Annotator: match by term: Pancreatic cancer 3 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 1
ClinVar Annotator: match by term: PALLD-related condition | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 1 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 2
ClinVar Annotator: match by term: PALLD-related condition | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 1 | ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 3
CTD Direct Evidence: marker/mechanism
protein:increased expression, alternative form:pancreas, fibroblast		 ClinVar
CTD
OMIM
RGD		 PMID:10454945 PMID:11474289 PMID:17194196 PMID:17415588 PMID:24033266 More... RGD:2325782, RGD:2325779 NCBI chr 4:168,497,052...168,928,441
Ensembl chr 4:168,497,052...168,928,457 		JBrowse link
G PBRM1 polybromo 1 TAS RGD PMID:23355908 RGD:8694154 NCBI chr 3:52,545,367...52,685,913
Ensembl chr 3:52,545,352...52,685,917 		JBrowse link
G PDGFRA platelet derived growth factor receptor alpha IMP
IEP		 mRNA:increased expression:pancreas RGD PMID:14695158 PMID:7665222 RGD:2324850, RGD:2324851 NCBI chr 4:54,229,293...54,298,245
Ensembl chr 4:54,229,280...54,298,245 		JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19077462 PMID:25086665 PMID:26098869 NCBI chr13:27,920,000...27,926,313
Ensembl chr13:27,920,000...27,926,313 		JBrowse link
G PFN1 profilin 1 IEP RGD PMID:16215274 RGD:2317552 NCBI chr17:4,945,652...4,948,530
Ensembl chr17:4,945,652...4,949,061 		JBrowse link
G PLAU plasminogen activator, urokinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:10467400 NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496 		JBrowse link
G POLB DNA polymerase beta disease_progression IAGP DNA:polymorphisms: :165A>G, 2133T>C (human) RGD PMID:17230526 RGD:2317132 NCBI chr 8:42,338,494...42,371,808
Ensembl chr 8:42,338,454...42,371,808 		JBrowse link
G PPARD peroxisome proliferator activated receptor delta disease_progression IEP
ISO		 RGD PMID:17652168 PMID:17652168 RGD:2324872, RGD:2324872 NCBI chr 6:35,342,558...35,428,178
Ensembl chr 6:35,342,558...35,428,191 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma susceptibility IAGP
EXP
IMP		 DNA:polymorphism: :p.P12A (human)
CTD Direct Evidence: marker/mechanism|therapeutic		 CTD
RGD		 PMID:11034103 PMID:11741176 PMID:19436234 PMID:19152448 RGD:2317460, RGD:2317462 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PTCH1 patched 1 IEP
EXP		 protein:increased expression:pancreas
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:19077462 PMID:19396459 RGD:2324910 NCBI chr 9:95,442,980...95,516,971
Ensembl chr 9:95,442,980...95,517,057 		JBrowse link
G PTEN phosphatase and tensin homolog TAS
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19917848 PMID:19506583 RGD:5490965 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 susceptibility IEP
EXP
IAGP
IMP		 mRNA, protein:increased expression:pancreas
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :-1195A > G, -765G > C (human)
DNA:polymorphisms: :-1195A>A ,-765G>C (human)		 CTD
RGD		 PMID:10485483 PMID:10657949 PMID:15705899 PMID:16820089 PMID:19820419 More... RGD:2317179, RGD:5135527, RGD:2317184, RGD:2317175 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTHLH parathyroid hormone like hormone EXP CTD Direct Evidence: marker/mechanism CTD PMID:17625444 NCBI chr12:27,958,084...27,972,733
Ensembl chr12:27,958,084...27,972,733 		JBrowse link
G RABL3 RAB, member of RAS oncogene family like 3 susceptibility IAGP
EXP		 ClinVar Annotator: match by term: Pancreatic cancer, susceptibility to, 5
ClinVar Annotator: match by term: RABL3-related condition
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:31406347 NCBI chr 3:120,684,938...120,742,680
Ensembl chr 3:120,684,938...120,742,993 		JBrowse link
G RAD51 RAD51 recombinase ISO protein:increased expression:pancreas (rat) RGD PMID:20197614 RGD:9831172 NCBI chr15:40,694,733...40,732,340
Ensembl chr15:40,694,774...40,732,340 		JBrowse link
G RAD54L RAD54 like IAGP DNA:SNP:exon:rs1048771 (human) RGD PMID:16540687 RGD:2317365 NCBI chr 1:46,247,688...46,278,473
Ensembl chr 1:46,246,461...46,278,480 		JBrowse link
G RAP1GAP RAP1 GTPase activating protein IEP
EXP		 mRNA:decreased expression:pancreas (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:22614916 PMID:16424023 RGD:9835037 NCBI chr 1:21,596,221...21,669,357
Ensembl chr 1:21,596,221...21,669,357 		JBrowse link
G RB1 RB transcriptional corepressor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21699781 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436 		JBrowse link
G RECQL RecQ like helicase IAGP
IMP		 DNA:SNP:3'utr:rs13035 (human)
DNA:SNPs:introns		 RGD PMID:16540687 PMID:19768149 PMID:18422747 RGD:2317365, RGD:2317369, RGD:2317370 NCBI chr12:21,468,910...21,501,635
Ensembl chr12:21,468,910...21,501,669 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit IEP RGD PMID:9918209 RGD:2298892 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RET ret proto-oncogene disease_progression IEP protein:increased expression:pancreas RGD PMID:16269310 RGD:2324926 NCBI chr10:43,077,069...43,130,351
Ensembl chr10:43,077,064...43,130,351 		JBrowse link
G RHBDD1 rhomboid domain containing 1 EXP CTD Direct Evidence: therapeutic CTD PMID:35442567 NCBI chr 2:226,800,159...226,999,210
Ensembl chr 2:226,835,581...226,999,215 		JBrowse link
G RRM2 ribonucleotide reductase regulatory subunit M2 IMP RGD PMID:19568409 RGD:2324950 NCBI chr 2:10,122,568...10,211,010
Ensembl chr 2:10,120,698...10,211,725 		JBrowse link
G RUNX3 RUNX family transcription factor 3 disease_progression IAGP DNA:hypermethylation, loss of heterozygosity (human) RGD PMID:18475302 RGD:2324956 NCBI chr 1:24,899,511...24,965,138
Ensembl chr 1:24,899,511...24,965,121 		JBrowse link
G RXRA retinoid X receptor alpha IMP RGD PMID:19152448 RGD:2317462 NCBI chr 9:134,326,455...134,440,585
Ensembl chr 9:134,317,098...134,440,585 		JBrowse link
G SEL1L SEL1L adaptor subunit of SYVN1 ubiquitin ligase IMP RGD PMID:14508516 RGD:2317190 NCBI chr14:81,471,547...81,533,853
Ensembl chr14:81,471,547...81,533,853 		JBrowse link
G SERPINA1 serpin family A member 1 disease_progression IEP RGD PMID:2323846 RGD:2324960 NCBI chr14:94,376,747...94,390,635
Ensembl chr14:94,376,747...94,390,693 		JBrowse link
G SF3B4 splicing factor 3b subunit 4 IEP mRNA, protein:decreased expression:pancreas (human) RGD PMID:28351319 RGD:155804299 NCBI chr 1:149,923,317...149,927,803
Ensembl chr 1:149,923,317...149,927,803 		JBrowse link
G SHH sonic hedgehog signaling molecule TAS RGD PMID:19506583 RGD:5490965 NCBI chr 7:155,799,980...155,812,463
Ensembl chr 7:155,799,980...155,812,463 		JBrowse link
G SINHCAF SIN3-HDAC complex associated factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:35213078 NCBI chr12:31,280,584...31,326,150
Ensembl chr12:31,280,584...31,327,058 		JBrowse link
G SLC1A5 solute carrier family 1 member 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:35929395 NCBI chr19:46,774,883...46,788,594
Ensembl chr19:46,774,883...46,788,594 		JBrowse link
G SLC29A1 solute carrier family 29 member 1 (Augustine blood group) EXP CTD Direct Evidence: marker/mechanism CTD PMID:18728667 NCBI chr 6:44,219,615...44,234,142
Ensembl chr 6:44,219,553...44,234,142 		JBrowse link
G SLCO2B1 solute carrier organic anion transporter family member 2B1 IEP mRNA:decreased expression:pancreas (human) RGD PMID:21625523 RGD:152995425 NCBI chr11:75,151,107...75,206,549
Ensembl chr11:75,100,563...75,206,549 		JBrowse link
G SMAD2 SMAD family member 2 IEP mRNA:increased expression:pancreas (human) RGD PMID:10505717 RGD:14394490 NCBI chr18:47,808,957...47,930,872
Ensembl chr18:47,808,957...47,931,146 		JBrowse link
G SMAD3 SMAD family member 3 IAGP DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr15:67,065,602...67,195,169
Ensembl chr15:67,063,763...67,195,173 		JBrowse link
G SMAD4 SMAD family member 4 IAGP
EXP		 DNA:mutations:exon
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Cancer of the pancreas		 CTD
ClinVar
OMIM
RGD		 PMID:25741868 PMID:18772397 RGD:5490966 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,528...51,085,045 		JBrowse link
G SMAD7 SMAD family member 7 IEP mRNA:increased expression:pancreas (human) RGD PMID:10498890 RGD:14394510 NCBI chr18:48,919,853...48,950,965
Ensembl chr18:48,919,853...48,950,965 		JBrowse link
G SMARCA4 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4 TAS RGD PMID:23355908 RGD:8694154 NCBI chr19:10,961,030...11,062,273
Ensembl chr19:10,960,932...11,079,426 		JBrowse link
G SMO smoothened, frizzled class receptor treatment ISO
IMP
IEP		 protein:increased expression:pancreas RGD PMID:19460966 PMID:22859707 PMID:19396459 RGD:2324978, RGD:150340554, RGD:2324910 NCBI chr 7:129,188,633...129,213,545
Ensembl chr 7:129,188,633...129,213,545 		JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 TAS RGD PMID:17726579 RGD:2302550 NCBI chr 7:99,027,440...99,144,108
Ensembl chr 7:99,027,440...99,144,108 		JBrowse link
G SNCG synuclein gamma IEP RGD PMID:15221989 RGD:6478801 NCBI chr10:86,955,759...86,963,258
Ensembl chr10:86,958,599...86,963,258 		JBrowse link
G SNW1 SNW domain containing 1 susceptibility IAGP DNA:snp:intron: T>A (human) (rs1477261) RGD PMID:20056645 RGD:11035249 NCBI chr14:77,717,599...77,761,156
Ensembl chr14:77,717,599...77,761,207 		JBrowse link
G SOD1 superoxide dismutase 1 IEP protein:decreased expression:pancreas RGD PMID:12499913 RGD:2317410 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SOD2 superoxide dismutase 2 susceptibility
disease_progression		 IAGP
EXP
IDA
IEP		 DNA:polymorphism:cds:p.A16V (human)
CTD Direct Evidence: marker/mechanism
protein:decreased expression:pancreas		 CTD
RGD		 PMID:11328670 PMID:17895890 PMID:18205184 PMID:12700280 PMID:12499913 RGD:2317406, RGD:1581235, RGD:2317410 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SPINK1 serine peptidase inhibitor Kazal type 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19896093 NCBI chr 5:147,824,582...147,839,196
Ensembl chr 5:147,824,572...147,831,671 		JBrowse link
G SPP1 secreted phosphoprotein 1 IDA RGD PMID:15970685 RGD:1581363 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532 		JBrowse link
G SST somatostatin EXP CTD Direct Evidence: therapeutic CTD PMID:2868874 NCBI chr 3:187,668,912...187,670,394
Ensembl chr 3:187,668,912...187,670,394 		JBrowse link
G SSTR1 somatostatin receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17625444 NCBI chr14:38,207,904...38,213,067
Ensembl chr14:38,207,904...38,213,067 		JBrowse link
G SSTR2 somatostatin receptor 2 EXP CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:15259086 PMID:17625444 PMID:19917848 NCBI chr17:73,165,010...73,176,633
Ensembl chr17:73,165,010...73,176,633 		JBrowse link
G SSTR3 somatostatin receptor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17625444 NCBI chr22:37,204,237...37,220,548
Ensembl chr22:37,204,237...37,212,477 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22348037 PMID:23845849 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G STK11 serine/threonine kinase 11 IAGP
EXP		 CTD Direct Evidence: marker/mechanism OMIM
CTD		 PMID:26098869 NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431 		JBrowse link
G SUGCT succinyl-CoA:glutarate-CoA transferase EXP CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr 7:40,135,005...41,038,816
Ensembl chr 7:40,135,005...40,860,763 		JBrowse link
G SYCP1 synaptonemal complex protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:14991579 NCBI chr 1:114,854,088...114,995,370
Ensembl chr 1:114,854,863...114,995,370 		JBrowse link
G TCF7L2 transcription factor 7 like 2 IAGP DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr10:112,950,247...113,167,678
Ensembl chr10:112,950,247...113,167,678 		JBrowse link
G TERT telomerase reverse transcriptase EXP CTD Direct Evidence: marker/mechanism CTD PMID:25086665 PMID:26098869 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068 		JBrowse link
G TFPI2 tissue factor pathway inhibitor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16965396 NCBI chr 7:93,885,396...93,890,753
Ensembl chr 7:93,885,396...93,890,753 		JBrowse link
G TGFA transforming growth factor alpha IEP
TAS
ISO		 mRNA, protein:increased expression:pancreas RGD PMID:1401070 PMID:19506583 PMID:17785207 RGD:2317473, RGD:5490965, RGD:2317468 NCBI chr 2:70,447,284...70,553,826
Ensembl chr 2:70,447,284...70,554,193 		JBrowse link
G TGFB1 transforming growth factor beta 1 disease_progression IEP
EXP		 CTD Direct Evidence: marker/mechanism
protein:increased expression:serum		 CTD
RGD		 PMID:23992306 PMID:18787407 PMID:16933058 RGD:2325015, RGD:2325018 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 disease_progression IEP
IAGP		 mRNA:increased expresssion:pancreas
DNA:mutations:exon
DNA:deletion, frameshift mutations (human)
protein:increased expresssion:pancreas		 RGD PMID:9365135 PMID:18772397 PMID:9850059 PMID:11866987 RGD:2317502, RGD:5490966, RGD:2317501, RGD:2317499 NCBI chr 3:30,606,356...30,694,142
Ensembl chr 3:30,606,478...30,694,249 		JBrowse link
G TGM2 transglutaminase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30108682 NCBI chr20:38,127,385...38,168,475
Ensembl chr20:38,127,385...38,166,578 		JBrowse link
G THBS1 thrombospondin 1 disease_progression IDA
IEP
IMP		 DNA:hypermethylation (human) RGD PMID:10766168 PMID:20203415 PMID:16757110 RGD:2325028, RGD:2325021, RGD:2325023 NCBI chr15:39,581,079...39,599,466
Ensembl chr15:39,581,079...39,599,466 		JBrowse link
G TNF tumor necrosis factor EXP CTD Direct Evidence: therapeutic CTD PMID:16211219 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF10B TNF receptor superfamily member 10b EXP CTD Direct Evidence: therapeutic CTD PMID:18089714 NCBI chr 8:23,020,133...23,069,031
Ensembl chr 8:23,020,133...23,069,031 		JBrowse link
G TNFSF10 TNF superfamily member 10 EXP CTD Direct Evidence: therapeutic CTD PMID:11234897 NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475 		JBrowse link
G TP53 tumor protein p53 IAGP
EXP
ISO		 DNA:mutations:exon
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:23873029 PMID:26390243 PMID:18772397 RGD:5490966 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TP53BP1 tumor protein p53 binding protein 1 ISO RGD PMID:11585747 RGD:2325154 NCBI chr15:43,403,061...43,510,640
Ensembl chr15:43,403,061...43,510,728 		JBrowse link
G TP63 tumor protein p63 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26098869 NCBI chr 3:189,596,746...189,897,276
Ensembl chr 3:189,631,389...189,897,276 		JBrowse link
G TSC2 TSC complex subunit 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19917848 NCBI chr16:2,047,985...2,089,491
Ensembl chr16:2,047,967...2,089,491 		JBrowse link
G TYMP thymidine phosphorylase IMP
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17443278 PMID:19671868 RGD:2325156 NCBI chr22:50,525,752...50,530,085
Ensembl chr22:50,525,752...50,530,032 		JBrowse link
G TYMS thymidylate synthetase EXP CTD Direct Evidence: marker/mechanism CTD PMID:19020767 NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578 		JBrowse link
G UCK2 uridine-cytidine kinase 2 IEP protein:increased expression:pancreatic neoplasm (human) RGD PMID:12149149 RGD:5133269 NCBI chr 1:165,827,614...165,911,618
Ensembl chr 1:165,827,614...165,911,618 		JBrowse link
G UGT1A7 UDP glucuronosyltransferase family 1 member A7 no_association IAGP DNA:polymorphisms: :p.N129K, p.R131K, p.W208R (human)
DNA:polymorphisms: :multiple (human)		 RGD PMID:12806614 PMID:17072959 RGD:2317503, RGD:2317157 NCBI chr 2:233,681,901...233,773,300
Ensembl chr 2:233,681,901...233,773,300 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 IEP RGD PMID:17652277 RGD:2325162 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045 		JBrowse link
G VEGFB vascular endothelial growth factor B EXP CTD Direct Evidence: marker/mechanism CTD PMID:24604347 NCBI chr11:64,234,584...64,239,264
Ensembl chr11:64,234,584...64,239,264 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor IAGP associated with Hippel-Lindau Disease;DNA:missense mutation:exon:p.R238Q (human)
DNA:hypermethylation, deletion:promoter (human)		 RGD PMID:9488521 PMID:19690016 RGD:2325176, RGD:2325169 NCBI chr 3:10,141,778...10,153,667
Ensembl chr 3:10,141,778...10,153,676 		JBrowse link
G WNT9A Wnt family member 9A IAGP DNA:mutations:exon RGD PMID:18772397 RGD:5490966 NCBI chr 1:227,918,656...227,947,932
Ensembl chr 1:227,918,656...227,947,932 		JBrowse link
G WT1 WT1 transcription factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:19196508 NCBI chr11:32,387,775...32,435,539
Ensembl chr11:32,387,775...32,435,564 		JBrowse link
G XPC XPC complex subunit, DNA damage recognition and repair factor IAGP DNA:polymorphism:intron:AF076952 (human) RGD PMID:18559563 RGD:2317130 NCBI chr 3:14,145,147...14,178,601
Ensembl chr 3:14,145,145...14,178,621 		JBrowse link
G XPO1 exportin 1 exacerbates IEP protein:increased expression:pancreas (human) RGD PMID:20003838 RGD:151665797 NCBI chr 2:61,477,849...61,538,612
Ensembl chr 2:61,476,032...61,538,741 		JBrowse link
G XPO5 exportin 5 ISO mRNA:decreased expression:pancreas (mouse) RGD PMID:26516699 RGD:11041739 NCBI chr 6:43,522,334...43,576,038
Ensembl chr 6:43,522,334...43,576,038 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 IAGP DNA:SNP:exon:rs1799782 (human) RGD PMID:16520463 RGD:2317367 NCBI chr19:43,543,311...43,575,527
Ensembl chr19:43,543,311...43,580,473 		JBrowse link
G XRCC2 X-ray repair cross complementing 2 IAGP DNA:SNP:exon:rs3218536 (human)
DNA:polymorphism: :p.R188H (human)		 RGD PMID:16540687 PMID:17986315 RGD:2317365, RGD:2317507 NCBI chr 7:152,644,776...152,676,141
Ensembl chr 7:152,644,776...152,676,193 		JBrowse link
G XRCC3 X-ray repair cross complementing 3 IAGP DNA:SNP:cd:rs861539 (human) RGD PMID:18559563 RGD:2317130 NCBI chr14:103,697,617...103,715,451
Ensembl chr14:103,697,609...103,715,504 		JBrowse link
G ZNRF3 zinc and ring finger 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25086665 PMID:26098869 NCBI chr22:28,883,572...29,057,488
Ensembl chr22:28,883,572...29,057,488 		JBrowse link
pancreatic carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1B activin A receptor type 1B IAGP ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:11248065 NCBI chr12:51,951,699...51,997,078
Ensembl chr12:51,951,699...51,997,078 		JBrowse link
G ATM ATM serine/threonine kinase IAGP ClinVar Annotator: match by term: Carcinoma of pancreas
ClinVar Annotator: match by term: PANCREATIC CARCINOMA		 ClinVar PMID:988733 PMID:1849795 PMID:3338800 PMID:8808599 PMID:9443866 More... NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102 		JBrowse link
G BRCA1 BRCA1 DNA repair associated IAGP ClinVar Annotator: match by term: Carcinoma of head of pancreas
ClinVar Annotator: match by term: Carcinoma of pancreas		 ClinVar PMID:9150174 PMID:10667592 PMID:10667595 PMID:11802209 PMID:12566964 More... NCBI chr17:43,044,295...43,170,327
Ensembl chr17:43,044,295...43,170,245 		JBrowse link
G BRCA2 BRCA2 DNA repair associated IAGP ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:8665505 PMID:9150150 PMID:9361038 PMID:9536098 PMID:9585613 More... NCBI chr13:32,315,077...32,400,268
Ensembl chr13:32,315,086...32,400,268 		JBrowse link
G BRIP1 BRCA1 interacting DNA helicase 1 IAGP ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:16116423 PMID:17033622 PMID:21964575 PMID:25330149 PMID:25741868 More... NCBI chr17:61,679,139...61,863,528
Ensembl chr17:61,679,139...61,863,559 		JBrowse link
G C11orf65 chromosome 11 open reading frame 65 IAGP ClinVar Annotator: match by term: Carcinoma of pancreas
ClinVar Annotator: match by term: PANCREATIC CARCINOMA		 ClinVar PMID:988733 PMID:1849795 PMID:3338800 PMID:8808599 PMID:9443866 More... NCBI chr11:108,308,519...108,469,881
Ensembl chr11:108,308,519...108,467,531 		JBrowse link
G CBR4 carbonyl reductase 4 IAGP ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:17194196 PMID:25741868 PMID:28492532 NCBI chr 4:168,894,486...169,010,255
Ensembl chr 4:168,863,770...169,010,275 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A IEP RGD PMID:9252195 RGD:8662427 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A susceptibility IAGP DNA:insertion:cds:p.R112_L113insR (human) RGD PMID:10922411 RGD:8552383 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301 		JBrowse link
G CHD3 chromodomain helicase DNA binding protein 3 disease_progression ISO protein:increased expression:pancreas RGD PMID:21472101 RGD:9587766 NCBI chr17:7,884,796...7,912,755
Ensembl chr17:7,884,796...7,912,760 		JBrowse link
G CHEK2 checkpoint kinase 2 IAGP ClinVar Annotator: match by term: PANCREATIC CARCINOMA
ClinVar Annotator: match by term: Carcinoma of pancreas		 ClinVar PMID:9536098 PMID:10617473 PMID:11053450 PMID:11479205 PMID:11719428 More... NCBI chr22:28,687,743...28,741,834
Ensembl chr22:28,687,743...28,742,422 		JBrowse link
G ERCC4 ERCC excision repair 4, endonuclease catalytic subunit IAGP ClinVar Annotator: match by term: PANCREATIC CARCINOMA ClinVar PMID:8797827 PMID:9579555 PMID:20221251 PMID:21228398 PMID:21612988 More... NCBI chr16:13,920,154...13,952,348
Ensembl chr16:13,920,138...13,952,348 		JBrowse link
G FANCE FA complementation group E IAGP ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:11001585 PMID:17924555 PMID:21279724 PMID:25741868 PMID:26822949 More... NCBI chr 6:35,452,338...35,467,102
Ensembl chr 6:35,452,338...35,467,104 		JBrowse link
G FANCG FA complementation group G IAGP ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar NCBI chr 9:35,073,839...35,079,942
Ensembl chr 9:35,073,835...35,080,004 		JBrowse link
G HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 severity ISO protein:increased expression:pancreas (rat) RGD PMID:21472101 RGD:9587766 NCBI chr 7:26,189,927...26,200,746
Ensembl chr 7:26,171,151...26,201,529 		JBrowse link
G HOXB13 homeobox B13 IAGP ClinVar Annotator: match by term: PANCREATIC CARCINOMA ClinVar PMID:8756292 PMID:15964834 PMID:17138648 PMID:22236224 PMID:22714738 More... NCBI chr17:48,724,763...48,728,750
Ensembl chr17:48,724,763...48,728,750 		JBrowse link
G KDR kinase insert domain receptor treatment IMP RGD PMID:17414626 RGD:126848809 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISS
IAGP		 OMIM:260350
ClinVar Annotator: match by term: PANCREATIC CARCINOMA
ClinVar Annotator: match by term: Carcinoma of pancreas		 MouseDO
ClinVar		 PMID:1875403 PMID:7773929 PMID:8439212 PMID:12110640 PMID:12720172 More... NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936 		JBrowse link
G LOC130062899 ATAC-STARR-seq lymphoblastoid active region 13597 IAGP ClinVar Annotator: match by term: PANCREATIC CARCINOMA
ClinVar Annotator: match by term: Carcinoma of pancreas		 ClinVar PMID:15800014 PMID:20393878 PMID:24033266 PMID:24728327 PMID:25741868 More... NCBI chr19:1,223,046...1,223,255 JBrowse link
G MIR155 microRNA 155 IEP miRNA:increased expression:serum RGD PMID:28660759 RGD:24922217 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044 		JBrowse link
G MTOR mechanistic target of rapamycin kinase treatment ISO RGD PMID:25425965 RGD:11570510 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISS OMIM:260350 MouseDO NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G NBN nibrin IAGP ClinVar Annotator: match by term: PANCREATIC CARCINOMA ClinVar PMID:9590180 PMID:9590181 PMID:9620777 PMID:10398434 PMID:10799436 More... NCBI chr 8:89,933,331...89,984,667
Ensembl chr 8:89,924,515...90,003,228 		JBrowse link
G PALB2 partner and localizer of BRCA2 IAGP ClinVar Annotator: match by term: PANCREATIC CARCINOMA ClinVar PMID:17200668 PMID:17200671 PMID:17200672 PMID:20122277 PMID:20412113 More... NCBI chr16:23,603,165...23,641,310
Ensembl chr16:23,603,160...23,641,321 		JBrowse link
G PALLD palladin, cytoskeletal associated protein IAGP ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:17194196 PMID:25741868 PMID:28492532 NCBI chr 4:168,497,052...168,928,441
Ensembl chr 4:168,497,052...168,928,457 		JBrowse link
G POLD1 DNA polymerase delta 1, catalytic subunit IAGP ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar NCBI chr19:50,384,323...50,418,018
Ensembl chr19:50,384,204...50,418,018 		JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase ISO mRNA:increased expression:pancreas (rat) RGD PMID:2278633 RGD:14392892 NCBI chr 3:12,583,601...12,664,117
Ensembl chr 3:12,582,101...12,664,201 		JBrowse link
G RBBP8 RB binding protein 8, endonuclease IAGP ClinVar Annotator: match by term: Carcinoma of pancreas ClinVar PMID:9811458 PMID:28492532 NCBI chr18:22,914,139...23,026,486
Ensembl chr18:22,798,261...23,026,488 		JBrowse link
G SMAD4 SMAD family member 4 IAGP ClinVar Annotator: match by term: PANCREATIC CARCINOMA
ClinVar Annotator: match by term: Carcinoma of pancreas | ClinVar Annotator: match by term: PANCREATIC CARCINOMA		 ClinVar PMID:8653691 PMID:9582123 PMID:9811934 PMID:10398437 PMID:10764709 More... NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,528...51,085,045 		JBrowse link
G STK11 serine/threonine kinase 11 IAGP ClinVar Annotator: match by term: Carcinoma of pancreas
ClinVar Annotator: match by term: PANCREATIC CARCINOMA
ClinVar Annotator: match by term: Carcinoma of pancreas | ClinVar Annotator: match by term: PANCREATIC CARCINOMA		 ClinVar PMID:10362809 PMID:11430832 PMID:15188174 PMID:15800014 PMID:16287113 More... NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431 		JBrowse link
G TP53 tumor protein p53 IAGP ClinVar Annotator: match by term: Carcinoma of pancreas
ClinVar Annotator: match by term: PANCREATIC CARCINOMA		 ClinVar PMID:1565143 PMID:1565144 PMID:1581912 PMID:1591732 PMID:1631137 More... NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TSC1 TSC complex subunit 1 ISO RGD PMID:25425965 RGD:11570510 NCBI chr 9:132,891,349...132,945,378
Ensembl chr 9:132,891,348...132,946,874 		JBrowse link
pancreatic ductal adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGR2 anterior gradient 2, protein disulphide isomerase family member IEP protein:increased expression:pancreas RGD PMID:19714807 RGD:2325658 NCBI chr 7:16,791,811...16,804,999
Ensembl chr 7:16,791,811...16,833,433 		JBrowse link
G AKR7A2 aldo-keto reductase family 7 member A2 IEP protein:increased expression:pancreas RGD PMID:19077459 RGD:2325696 NCBI chr 1:19,302,708...19,312,146
Ensembl chr 1:19,301,991...19,312,144 		JBrowse link
G CALR calreticulin ameliorates IMP human cells in mouse model
human cells in a mouse model		 RGD PMID:33028359 PMID:29072694 RGD:150520160, RGD:150521706 NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489 		JBrowse link
G CCND1 cyclin D1 severity IAGP
IEP		 DNA:snp:exon:c.870G>A (human)
protein:increased expression:pancreas (human)		 RGD PMID:25470788 PMID:22939953 RGD:13462050, RGD:13462062 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CD59 CD59 molecule (CD59 blood group) disease_progression IEP protein:increased expression:blood (human) RGD PMID:32663515 RGD:151660329 NCBI chr11:33,703,010...33,736,479
Ensembl chr11:33,703,010...33,736,479 		JBrowse link
G CDK4 cyclin dependent kinase 4 severity IEP protein:increased expression:pancreas, islet of Langerhans (human) RGD PMID:29735403 RGD:13781899 NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013 		JBrowse link
G CFHR3 complement factor H related 3 disease_progression IEP protein:decreased expression:blood (human) RGD PMID:32663515 RGD:151660329 NCBI chr 1:196,774,840...196,795,407
Ensembl chr 1:196,774,813...196,795,407 		JBrowse link
G E2F1 E2F transcription factor 1 severity IEP
IAGP		 protein:increased expression:pancreatic ductal cell, nucleus (human)
DNA:amplification: : (human)		 RGD PMID:12650514 PMID:17233815 PMID:27573434 RGD:13838735, RGD:13838739, RGD:13838738 NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385 		JBrowse link
G FOXM1 forkhead box M1 disease_progression IEP RGD PMID:24859161 RGD:156430321 NCBI chr12:2,857,680...2,877,174
Ensembl chr12:2,857,680...2,877,174 		JBrowse link
G FUBP1 far upstream element binding protein 1 IEP mRNA:increased expression:pancreatic duct (human) RGD PMID:32481602 RGD:151361197 NCBI chr 1:77,944,055...77,979,501
Ensembl chr 1:77,944,055...77,979,110 		JBrowse link
G GLIPR2 GLI pathogenesis related 2 disease_progression IEP protein:decreased expression:blood (human) RGD PMID:32663515 RGD:151660329 NCBI chr 9:36,136,536...36,163,913
Ensembl chr 9:36,136,536...36,163,913 		JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 treatment IMP human cells in a mouse model RGD PMID:23535601 RGD:13504844 NCBI chr10:99,396,870...99,430,624
Ensembl chr10:99,396,870...99,430,624 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 disease_progression IEP protein:decreased expression:blood (human) RGD PMID:32663515 RGD:151660329 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta susceptibility ISO RGD PMID:22264792 RGD:13838741 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G JAK1 Janus kinase 1 IEP mRNA:decreased expression:pancreatic ductal cell (human) RGD PMID:28677798 RGD:13838745 NCBI chr 1:64,833,229...65,067,746
Ensembl chr 1:64,833,223...65,067,754 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 severity
disease_progression		 ISO protein:increased phosphorylation:pancreas (mouse) RGD PMID:28837246 PMID:23237571 RGD:14348974, RGD:14348975 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MIR155 microRNA 155 disease_progression IEP RGD PMID:28198398 RGD:25314300 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044 		JBrowse link
G MIR494 microRNA 494 disease_progression
ameliorates		 IEP
IDA		 RGD PMID:24859161 PMID:24859161 RGD:156430321, RGD:156430321 NCBI chr14:101,029,634...101,029,714
Ensembl chr14:101,029,634...101,029,714 		JBrowse link
G PGF placental growth factor severity ISO associated with obesity RGD PMID:26861455 RGD:14349030 NCBI chr14:74,941,830...74,955,764
Ensembl chr14:74,941,834...74,955,626 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma IEP mRNA, protein:increased expression:pancreas (human) RGD PMID:20876794 RGD:14390130 NCBI chr 7:106,865,282...106,908,980
Ensembl chr 7:106,865,278...106,908,980 		JBrowse link
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 severity IMP human cells in a mouse model RGD PMID:15591514 RGD:14390084 NCBI chr19:18,153,163...18,170,532
Ensembl chr19:18,153,163...18,170,540 		JBrowse link
G PLD1 phospholipase D1 severity IEP protein:increased expression:pancreas (human) RGD PMID:27713167 RGD:14392801 NCBI chr 3:171,600,404...171,810,483
Ensembl chr 3:171,600,404...171,810,950 		JBrowse link
G PTPRB protein tyrosine phosphatase receptor type B disease_progression IEP protein:decreased expression:blood (human) RGD PMID:32663515 RGD:151660329 NCBI chr12:70,515,870...70,637,429
Ensembl chr12:70,515,870...70,637,440 		JBrowse link
G PTPRM protein tyrosine phosphatase receptor type M disease_progression IEP protein:decreased expression:blood (human) RGD PMID:32663515 RGD:151660329 NCBI chr18:7,567,316...8,406,856
Ensembl chr18:7,566,782...8,406,861 		JBrowse link
G RAC1 Rac family small GTPase 1 IEP
ISO		 mRNA:increased expression:pancreas (human)
mRNA, protein:increased expression:pancreas (mouse)		 RGD PMID:23334332 PMID:21684285 RGD:14392806, RGD:14392816 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967 		JBrowse link
G RALA RAS like proto-oncogene A IEP mRNA:increased expression:pancreas (human) RGD PMID:29113235 RGD:14394418 NCBI chr 7:39,623,572...39,708,120
Ensembl chr 7:39,623,565...39,708,120 		JBrowse link
G S100A8 S100 calcium binding protein A8 disease_progression IEP protein:increased expression:blood (human) RGD PMID:32663515 RGD:151660329 NCBI chr 1:153,390,032...153,422,583
Ensembl chr 1:153,390,032...153,391,073 		JBrowse link
G SMAD2 SMAD family member 2 severity IEP RGD PMID:26908446 RGD:14394493 NCBI chr18:47,808,957...47,930,872
Ensembl chr18:47,808,957...47,931,146 		JBrowse link
G TGFB1 transforming growth factor beta 1 ameliorates IEP protein:decreased expression:pancreas (human) RGD PMID:8253361 RGD:155630628 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TGFB2 transforming growth factor beta 2 ameliorates IEP protein:decreased expression:pancreas (human) RGD PMID:8253361 RGD:155630628 NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619 		JBrowse link
G TGFB3 transforming growth factor beta 3 ameliorates IEP protein:decreased expression:pancreas (human) RGD PMID:8253361 RGD:155630628 NCBI chr14:75,958,097...75,983,011
Ensembl chr14:75,958,097...75,983,011 		JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 ameliorates IMP human cell line in a mouse model RGD PMID:17297450 RGD:155630637 NCBI chr 9:99,103,647...99,154,192
Ensembl chr 9:99,104,038...99,154,192 		JBrowse link
G VEGFD vascular endothelial growth factor D IEP protein:increased expression:blood serum (human) RGD PMID:21410412 RGD:155630646 NCBI chr  X:15,345,596...15,384,413
Ensembl chr  X:15,345,596...15,384,413 		JBrowse link
G VNN1 vanin 1 disease_progression IEP protein:increased expression:blood (human) RGD PMID:32663515 RGD:151660329 NCBI chr 6:132,680,849...132,714,055
Ensembl chr 6:132,680,849...132,714,055 		JBrowse link
pancreatic ductal carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme IEP mRNA, protein:increased expression:pancreas RGD PMID:17481528 RGD:2325211 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ACE2 angiotensin converting enzyme 2 IEP protein:decreased expression:pancreas RGD PMID:19212105 RGD:2325210 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236 		JBrowse link
G ADAM8 ADAM metallopeptidase domain 8 disease_progression IEP mRNA:increased expression:pancreas RGD PMID:17979891 RGD:2325243 NCBI chr10:133,262,423...133,276,868
Ensembl chr10:133,262,420...133,276,868 		JBrowse link
G ADAM9 ADAM metallopeptidase domain 9 disease_progression IEP protein:altered localization:cytoplasm RGD PMID:14997207 RGD:2325249 NCBI chr 8:38,996,973...39,105,261
Ensembl chr 8:38,996,754...39,105,445 		JBrowse link
G AGR2 anterior gradient 2, protein disulphide isomerase family member IEP mRNA:increased expression:pancreas RGD PMID:19609859 RGD:2325659 NCBI chr 7:16,791,811...16,804,999
Ensembl chr 7:16,791,811...16,833,433 		JBrowse link
G AGTR1 angiotensin II receptor type 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17481528 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008 		JBrowse link
G ALB albumin disease_progression IEP RGD PMID:19011933 RGD:2325677 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G ANXA2 annexin A2 disease_progression IEP mRNA, protein:increased expression, altered localization:pancreas, plasma membrane RGD PMID:19260470 PMID:16450333 RGD:2317307, RGD:2325731 NCBI chr15:60,347,151...60,397,986
Ensembl chr15:60,347,134...60,402,883 		JBrowse link
G ANXA5 annexin A5 IEP protein:increased expression:pancreas RGD PMID:19488907 RGD:2317538 NCBI chr 4:121,667,946...121,696,980
Ensembl chr 4:121,667,946...121,696,995 		JBrowse link
G ANXA8 annexin A8 IEP mRNA:increased expression:pancreas RGD PMID:18223320 RGD:2325735 NCBI chr10:47,467,993...47,991,796
Ensembl chr10:47,460,162...47,484,158 		JBrowse link
G APOC1 apolipoprotein C1 IEP RGD PMID:15876873 RGD:2325793 NCBI chr19:44,914,325...44,919,346
Ensembl chr19:44,914,247...44,919,349 		JBrowse link
G ARG2 arginase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23424623 NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708 		JBrowse link
G BMI1 BMI1 proto-oncogene, polycomb ring finger ISO
IEP		 protein:increased expression:pancreas
protein:increased expression:exocrine pancreas: 		RGD PMID:19585519 PMID:19585519 RGD:9491843, RGD:9491843 NCBI chr10:22,321,099...22,331,706
Ensembl chr10:22,321,099...22,331,484 		JBrowse link
G C19orf33 chromosome 19 open reading frame 33 EXP CTD Direct Evidence: marker/mechanism CTD PMID:35142956 NCBI chr19:38,304,251...38,305,006
Ensembl chr19:38,304,164...38,305,006 		JBrowse link
G CALR calreticulin IEP protein:increased expression:pancreatic duct RGD PMID:15289361 RGD:2326165 NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489 		JBrowse link
G CBX7 chromobox 7 disease_progression IEP protein:decreased expression:pancreas RGD PMID:20185297 RGD:9587360 NCBI chr22:39,130,772...39,152,680
Ensembl chr22:39,120,167...39,152,680 		JBrowse link
G CCKAR cholecystokinin A receptor IEP protein:decreased expression:pancreas
mRNA:increased expression:pancreatic duct		 RGD PMID:12851875 PMID:9239407 RGD:4110816, RGD:4110818 NCBI chr 4:26,481,396...26,490,484
Ensembl chr 4:26,481,396...26,490,484 		JBrowse link
G CCKBR cholecystokinin B receptor IEP protein:decreased expression:pancreas RGD PMID:12851875 RGD:4110816 NCBI chr11:6,259,838...6,272,127
Ensembl chr11:6,259,806...6,272,127 		JBrowse link
G CCND1 cyclin D1 severity IEP protein:increased expression:pancreas (human) RGD PMID:17420962 RGD:13462063 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CD40 CD40 molecule treatment IDA
IMP
IEP		 protein:increased expression:dendritic cell RGD PMID:21436454 PMID:23983255 PMID:20976171 RGD:5490301, RGD:11522743, RGD:5490524 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CDK6 cyclin dependent kinase 6 treatment IDA human cells in a mouse model RGD PMID:24389175 RGD:13782187 NCBI chr 7:92,604,921...92,836,573
Ensembl chr 7:92,604,921...92,836,573 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A disease_progression IEP RGD PMID:17671118 RGD:8662851 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A EXP CTD Direct Evidence: marker/mechanism CTD PMID:24986516 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301 		JBrowse link
G CLDN4 claudin 4 IEP RGD PMID:15693851 RGD:2317592 NCBI chr 7:73,830,996...73,832,690
Ensembl chr 7:73,799,542...73,832,690 		JBrowse link
G CXCL11 C-X-C motif chemokine ligand 11 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24979617 NCBI chr 4:76,033,682...76,036,070
Ensembl chr 4:76,033,682...76,041,415 		JBrowse link
G DNMT1 DNA methyltransferase 1 disease_progression IEP
EXP		 protein:increased expression:pancreas
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:29844410 PMID:19424621 RGD:9588974 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta disease_progression IEP RGD PMID:22919364 RGD:9589121 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359 		JBrowse link
G DTX1 deltex E3 ubiquitin ligase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr12:113,056,730...113,098,025
Ensembl chr12:113,056,730...113,098,028 		JBrowse link
G DTX4 deltex E3 ubiquitin ligase 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr11:59,171,430...59,208,588
Ensembl chr11:59,171,430...59,208,588 		JBrowse link
G EGF epidermal growth factor disease_progression IEP protein:increased expression: : RGD PMID:18505086 RGD:2317644 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G FASLG Fas ligand IEP
IDA		 protein:increased expression:pancreas, liver RGD PMID:15375495 PMID:10547193 RGD:2317741, RGD:2317747 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G FGF2 fibroblast growth factor 2 disease_progression IEP RGD PMID:12717266 PMID:18704599 RGD:2317758, RGD:2317756 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236 		JBrowse link
G FSCN1 fascin actin-bundling protein 1 disease_progression IEP protein:increased expression:pancreas RGD PMID:12109856 RGD:2317790 NCBI chr 7:5,592,816...5,606,655
Ensembl chr 7:5,592,816...5,606,655 		JBrowse link
G GPNMB glycoprotein nmb EXP CTD Direct Evidence: marker/mechanism CTD PMID:24979617 NCBI chr 7:23,246,775...23,275,108
Ensembl chr 7:23,235,967...23,275,108 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 resistance IEP
IAGP
IDA		 mRNA, protein:increased expression:pancreas
DNA:methylation: :		 RGD PMID:12488200 PMID:17265526 PMID:16537562 RGD:2317811, RGD:2317806, RGD:2317809 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G HDAC1 histone deacetylase 1 disease_progression IEP protein:increased expression:pancreas RGD PMID:19424621 RGD:9588974 NCBI chr 1:32,292,083...32,333,626
Ensembl chr 1:32,292,083...32,333,635 		JBrowse link
G HEATR1 HEAT repeat containing 1 treatment IMP RGD PMID:26676747 RGD:10761108 NCBI chr 1:236,549,005...236,604,516
Ensembl chr 1:236,549,005...236,604,516 		JBrowse link
G HES1 hes family bHLH transcription factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732 		JBrowse link
G HEY1 hes related family bHLH transcription factor with YRPW motif 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr 8:79,764,010...79,767,767
Ensembl chr 8:79,762,371...79,767,857 		JBrowse link
G HEY2 hes related family bHLH transcription factor with YRPW motif 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr 6:125,749,632...125,761,269
Ensembl chr 6:125,747,664...125,761,269 		JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A EXP CTD Direct Evidence: marker/mechanism CTD PMID:17234771 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946 		JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B EXP CTD Direct Evidence: marker/mechanism CTD PMID:17234771 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254 		JBrowse link
G IGF1 insulin like growth factor 1 ISO RGD PMID:20098680 RGD:2317639 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
G IGF1R insulin like growth factor 1 receptor IEP protein:increased expression:pancreas RGD PMID:14506643 PMID:14627343 RGD:2317652, RGD:2317649 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530 		JBrowse link
G IL4 interleukin 4 IMP RGD PMID:17942922 RGD:2317264 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL4R interleukin 4 receptor IEP protein:increased expression:pancreas RGD PMID:17942922 RGD:2317264 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778 		JBrowse link
G INS insulin IEP Glucagon/insulin RGD PMID:19571666 RGD:2317248 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221 		JBrowse link
G JAG1 jagged canonical Notch ligand 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr20:10,637,684...10,673,999
Ensembl chr20:10,637,684...10,673,999 		JBrowse link
G JAG2 jagged canonical Notch ligand 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr14:105,140,995...105,168,776
Ensembl chr14:105,140,982...105,168,824 		JBrowse link
G KDM2B lysine demethylase 2B severity IEP mRNA, protein:increased expression:pancreas (human) RGD PMID:23321669 RGD:9588253 NCBI chr12:121,408,461...121,582,279
Ensembl chr12:121,429,096...121,582,279 		JBrowse link
G KITLG KIT ligand EXP CTD Direct Evidence: marker/mechanism CTD PMID:24979617 NCBI chr12:88,492,793...88,580,471
Ensembl chr12:88,492,793...88,580,851 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase EXP CTD Direct Evidence: marker/mechanism CTD PMID:25347530 PMID:30654191 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936 		JBrowse link
G KRT7 keratin 7 disease_progression IEP RGD PMID:19260470 RGD:2317307 NCBI chr12:52,233,243...52,255,853
Ensembl chr12:52,232,520...52,252,186 		JBrowse link
G L1CAM L1 cell adhesion molecule severity IEP protein:increased expression:pancreas (human) RGD PMID:20162456 RGD:6483447 NCBI chr  X:153,861,514...153,886,173
Ensembl chr  X:153,861,514...153,886,173 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34686948 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 treatment IDA human cells in mouse model RGD PMID:20179210 RGD:14348973 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MCM7 minichromosome maintenance complex component 7 IEP mRNA, protein:increased expression:pancreatic duct RGD PMID:15548371 RGD:2317697 NCBI chr 7:100,092,728...100,101,397
Ensembl chr 7:100,092,233...100,101,940 		JBrowse link
G MDM2 MDM2 proto-oncogene severity
onset		 IEP
IAGP		 protein:increased expression:pancreas (human)
DNA:snp:promoter, intron:IVS1+309T>G (human)		 RGD PMID:15810085 PMID:19752772 RGD:2317416, RGD:2317414 NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544 		JBrowse link
G MEN1 menin 1 IEP
IDA		 protein:decreased expression:pancreas RGD PMID:19170121 PMID:19170121 RGD:2317294, RGD:2317294 NCBI chr11:64,803,516...64,811,294
Ensembl chr11:64,803,510...64,811,294 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase IEP protein:increased expression:pancreatic duct (human) RGD PMID:7866999 RGD:2317530 NCBI chr 7:116,672,196...116,798,377
Ensembl chr 7:116,672,196...116,798,377 		JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase susceptibility IEP
IAGP		 protein:increased activity, increased expression:ductal adenocarcinoma (human)
DNA:missense mutation:cds:p.L84F rs12917 (human)		 RGD PMID:9393761 PMID:16844323 RGD:2317664, RGD:2317648 NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983 		JBrowse link
G MIR142 microRNA 142 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29844410 NCBI chr17:58,331,232...58,331,318
Ensembl chr17:58,331,232...58,331,318 		JBrowse link
G MIR873 microRNA 873 EXP CTD Direct Evidence: therapeutic CTD PMID:30654191 NCBI chr 9:28,888,879...28,888,955
Ensembl chr 9:28,888,879...28,888,955 		JBrowse link
G MMP2 matrix metallopeptidase 2 severity IEP protein:increased expression:pancreas RGD PMID:17377415 RGD:2325746 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP9 matrix metallopeptidase 9 IEP protein:increased expression:blood
protein:increased expression:pancreas, serum		 RGD PMID:20332475 PMID:18706098 RGD:2325830, RGD:2325844 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MSLN mesothelin disease_progression IDA
EXP
IEP		 DNA:hypomethylation:5'UTR
CTD Direct Evidence: marker/mechanism
protein:increased secretion:serum		 CTD
RGD		 PMID:14576474 PMID:21775916 PMID:25347530 PMID:12874021 PMID:19818733 RGD:2326065, RGD:2326055 NCBI chr16:760,734...768,865
Ensembl chr16:760,734...768,865 		JBrowse link
G MUC1 mucin 1, cell surface associated disease_progression IEP
IMP
IDA		 protein:increased expression, altered localization:pancreas RGD PMID:14681945 PMID:18713982 PMID:19109152 RGD:2317983, RGD:2324633, RGD:2324616 NCBI chr 1:155,185,824...155,192,915
Ensembl chr 1:155,185,824...155,192,916 		JBrowse link
G MUC3A mucin 3A, cell surface associated disease_progression IEP mRNA:increased expression:pancreas RGD PMID:12657964 RGD:2324946 NCBI chr 7:100,949,534...100,968,347
Ensembl chr 7:100,949,534...100,968,347 		JBrowse link
G MUC4 mucin 4, cell surface associated disease_progression IEP mRNA:increased expression:pancreas
protein:increased expression:pancreas		 RGD PMID:12657964 PMID:16049287 RGD:2324946, RGD:2324942 NCBI chr 3:195,746,771...195,811,929
Ensembl chr 3:195,746,765...195,811,973 		JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming disease_progression IEP mRNA:increased expression:pancreas RGD PMID:7657125 PMID:10227724 RGD:2324986, RGD:2324907 NCBI chr11:1,157,953...1,201,138
Ensembl chr11:1,157,953...1,201,138 		JBrowse link
G MUC5B mucin 5B, oligomeric mucus/gel-forming IEP mRNA:increased expression:pancreas RGD PMID:7657125 RGD:2324986 NCBI chr11:1,223,066...1,262,172
Ensembl chr11:1,223,066...1,262,172 		JBrowse link
G NDRG1 N-myc downstream regulated 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16778198 NCBI chr 8:133,237,175...133,297,252
Ensembl chr 8:133,237,175...133,302,022 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21489257 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NME1 NME/NM23 nucleoside diphosphate kinase 1 IEP protein:increased expression:pancreas (human) RGD PMID:17492507 RGD:5132867 NCBI chr17:51,153,559...51,162,168
Ensembl chr17:51,153,559...51,162,428 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO RGD PMID:12660813 RGD:2325254 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOTCH1 notch receptor 1 ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19208345 PMID:20484026 PMID:19028876 RGD:2325323, RGD:2325324 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048 		JBrowse link
G NOTCH3 notch receptor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr19:15,159,038...15,200,995
Ensembl chr19:15,159,038...15,200,995 		JBrowse link
G NOTCH4 notch receptor 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19208345 NCBI chr 6:32,194,843...32,224,067
Ensembl chr 6:32,194,843...32,224,067 		JBrowse link
G NTRK3 neurotrophic receptor tyrosine kinase 3 disease_progression IEP protein:increased expression:pancreas RGD PMID:10209957 PMID:11295066 RGD:2325663, RGD:2325660 NCBI chr15:87,859,751...88,256,739
Ensembl chr15:87,859,751...88,256,791 		JBrowse link
G OSM oncostatin M EXP CTD Direct Evidence: marker/mechanism CTD PMID:24979617 NCBI chr22:30,262,829...30,266,851
Ensembl chr22:30,262,829...30,266,851 		JBrowse link
G PALLD palladin, cytoskeletal associated protein IEP protein:increased expression, alternative form:pancreas, fibroblast RGD PMID:17404500 RGD:2325781 NCBI chr 4:168,497,052...168,928,441
Ensembl chr 4:168,497,052...168,928,457 		JBrowse link
G PAX6 paired box 6 IEP protein:increased expression:pancreatic duct (human) RGD PMID:17849422 RGD:8552381 NCBI chr11:31,789,026...31,817,961
Ensembl chr11:31,784,779...31,817,961 		JBrowse link
G PMS1 PMS1 homolog 1, mismatch repair system component IDA protein:increased expression:pancreatic duct RGD PMID:15856462 RGD:2324870 NCBI chr 2:189,784,450...189,877,629
Ensembl chr 2:189,784,085...189,877,629 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma disease_progression IEP RGD PMID:19396032 RGD:2317461 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:18670639 RGD:2317185 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:34686948 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RNF2 ring finger protein 2 IEP protein:increased expression:pancreas RGD PMID:19585519 RGD:9491843 NCBI chr 1:185,045,558...185,102,603
Ensembl chr 1:185,045,497...185,102,603 		JBrowse link
G RXRA retinoid X receptor alpha severity IEP RGD PMID:19396032 RGD:2317461 NCBI chr 9:134,326,455...134,440,585
Ensembl chr 9:134,317,098...134,440,585 		JBrowse link
G SERPINA1 serpin family A member 1 IEP mRNA, protein:increased expression:pancreas RGD PMID:12488200 RGD:2317811 NCBI chr14:94,376,747...94,390,635
Ensembl chr14:94,376,747...94,390,693 		JBrowse link
G SLC2A2 solute carrier family 2 member 2 ISO protein:increased expression:pancreatic duct RGD PMID:19252908 RGD:2324975 NCBI chr 3:170,996,347...171,026,720
Ensembl chr 3:170,996,347...171,026,743 		JBrowse link
G SMAD4 SMAD family member 4 disease_progression IEP RGD PMID:15173084 RGD:21066334 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,528...51,085,045 		JBrowse link
G SMO smoothened, frizzled class receptor IMP RGD PMID:16826192 RGD:2324981 NCBI chr 7:129,188,633...129,213,545
Ensembl chr 7:129,188,633...129,213,545 		JBrowse link
G STK11 serine/threonine kinase 11 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26887594 NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431 		JBrowse link
G TGFB1 transforming growth factor beta 1 disease_progression IEP RGD PMID:16101174 RGD:2325019 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 disease_progression ISO
IEP		 mRNA:increased expresssion:pancreas RGD PMID:17114585 PMID:10547197 RGD:2317498, RGD:2317500 NCBI chr 3:30,606,356...30,694,142
Ensembl chr 3:30,606,478...30,694,249 		JBrowse link
G THBS1 thrombospondin 1 disease_progression IEP
IDA		 DNA:hypermethylation:promoter (human) RGD PMID:12429967 PMID:19065635 RGD:2325025, RGD:2325022 NCBI chr15:39,581,079...39,599,466
Ensembl chr15:39,581,079...39,599,466 		JBrowse link
G TMPRSS3 transmembrane serine protease 3 IEP RGD PMID:14695172 RGD:2325152 NCBI chr21:42,371,890...42,396,052
Ensembl chr21:42,371,887...42,396,091 		JBrowse link
G TP53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29844410 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TSC2 TSC complex subunit 2 severity IEP RGD PMID:16213898 RGD:11568674 NCBI chr16:2,047,985...2,089,491
Ensembl chr16:2,047,967...2,089,491 		JBrowse link
G TYMP thymidine phosphorylase disease_progression IEP RGD PMID:19760965 RGD:2325155 NCBI chr22:50,525,752...50,530,085
Ensembl chr22:50,525,752...50,530,032 		JBrowse link
G VEGFA vascular endothelial growth factor A EXP CTD Direct Evidence: marker/mechanism CTD PMID:17481528 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor IDA DNA:hypermethylation:promoter (human) RGD PMID:19065635 RGD:2325022 NCBI chr 3:10,141,778...10,153,667
Ensembl chr 3:10,141,778...10,153,676 		JBrowse link
G YEATS2 YEATS domain containing 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34686948 NCBI chr 3:183,697,797...183,812,624
Ensembl chr 3:183,697,797...183,812,624 		JBrowse link
G ZZZ3 zinc finger ZZ-type containing 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34686948 NCBI chr 1:77,562,416...77,683,398
Ensembl chr 1:77,562,416...77,683,419 		JBrowse link
pancreatic endocrine carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRCA2 BRCA2 DNA repair associated IAGP ClinVar Annotator: match by term: Neuroendocrine tumor of pancreas ClinVar PMID:15145354 PMID:22762150 PMID:25741868 PMID:29446198 NCBI chr13:32,315,077...32,400,268
Ensembl chr13:32,315,086...32,400,268 		JBrowse link
G CUX1 cut like homeobox 1 exacerbates HEP protein:increased expression:pancreas (human) RGD PMID:32707646 RGD:153297777 NCBI chr 7:101,816,007...102,283,958
Ensembl chr 7:101,815,904...102,283,958 		JBrowse link
G DAXX death domain associated protein disease_progression IAGP DNA:frameshift, frameshift mutations, nonsense mutation, missense mutations:CDS:multiple (human) RGD PMID:29212165 RGD:152025205 NCBI chr 6:33,318,558...33,322,959
Ensembl chr 6:33,318,558...33,323,016 		JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase IAGP DNA:hypermethylation:promoter (human) RGD PMID:14501508 RGD:2317661 NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983 		JBrowse link
G PALB2 partner and localizer of BRCA2 IAGP ClinVar Annotator: match by term: Neuroendocrine tumor of pancreas ClinVar PMID:17200668 PMID:17200671 PMID:17200672 PMID:24136930 PMID:25099575 More... NCBI chr16:23,603,165...23,641,310
Ensembl chr16:23,603,160...23,641,321 		JBrowse link
G PGF placental growth factor disease_progression
treatment		 IEP
IMP		 protein:increased expression:serum (human)
human cells in a mouse model		 RGD PMID:23463017 PMID:26861455 RGD:14349029, RGD:14349030 NCBI chr14:74,941,830...74,955,764
Ensembl chr14:74,941,834...74,955,626 		JBrowse link
pancreatic intraductal papillary-mucinous neoplasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 IAGP DNA:missense mutation:cds:p.E17K (human) RGD PMID:24132918 RGD:13462042 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G TP53 tumor protein p53 IAGP DNA:missense mutations: :multiple RGD PMID:28930868 RGD:14995501 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G VEGFD vascular endothelial growth factor D IEP protein:increased expression:blood serum (human) RGD PMID:21410412 RGD:155630646 NCBI chr  X:15,345,596...15,384,413
Ensembl chr  X:15,345,596...15,384,413 		JBrowse link
Pancreatic Intraepithelial Neoplasia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGR2 anterior gradient 2, protein disulphide isomerase family member IEP protein:increased expression:pancreas RGD PMID:19714807 RGD:2325658 NCBI chr 7:16,791,811...16,804,999
Ensembl chr 7:16,791,811...16,833,433 		JBrowse link
G BMI1 BMI1 proto-oncogene, polycomb ring finger ISO
IEP		 protein:increased expression:pancreatic acinar cell:
protein:increased expression:exocrine pancreas: 		RGD PMID:19585519 PMID:19585519 RGD:9491843, RGD:9491843 NCBI chr10:22,321,099...22,331,706
Ensembl chr10:22,321,099...22,331,484 		JBrowse link
G CBX7 chromobox 7 disease_progression IEP protein:decreased expression:pancreas RGD PMID:20185297 RGD:9587360 NCBI chr22:39,130,772...39,152,680
Ensembl chr22:39,120,167...39,152,680 		JBrowse link
G CCND1 cyclin D1 disease_progression IEP protein:increased expression:pancreas (human) RGD PMID:12882690 PMID:11751405 RGD:13462061, RGD:13464129 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G DNMT1 DNA methyltransferase 1 IEP protein:increased expression:pancreas RGD PMID:19424621 RGD:9588974 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286 		JBrowse link
G HDAC1 histone deacetylase 1 IEP protein:increased expression:pancreas RGD PMID:19424621 RGD:9588974 NCBI chr 1:32,292,083...32,333,626
Ensembl chr 1:32,292,083...32,333,635 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta severity
disease_progression		 ISO RGD PMID:22406536 PMID:22056382 RGD:13838740, RGD:13838742 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
pancreatic mucinous cystadenoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KRAS KRAS proto-oncogene, GTPase severity IAGP DNA:mutations:cds: RGD PMID:28570009 RGD:14398747 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936 		JBrowse link
pancreatic solid pseudopapillary carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCND1 cyclin D1 severity IEP protein:increased expression:pancreas (human) RGD PMID:19248223 RGD:13462054 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
vipoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNA1 interferon alpha 1 EXP CTD Direct Evidence: therapeutic CTD PMID:17961653 NCBI chr 9:21,440,439...21,441,316
Ensembl chr 9:21,440,439...21,441,316 		JBrowse link
G MEN1 menin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17961653 NCBI chr11:64,803,516...64,811,294
Ensembl chr11:64,803,510...64,811,294 		JBrowse link
G SST somatostatin EXP CTD Direct Evidence: therapeutic CTD PMID:2868874 NCBI chr 3:187,668,912...187,670,394
Ensembl chr 3:187,668,912...187,670,394 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 145369
    disease of anatomical entity 132557
      endocrine system disease 24621
        pancreas disease 4083
          Pancreatic Neoplasms 698
            Pancreatic Benign Neoplasm + 14
            islet cell tumor + 40
            pancreatic cancer + 695
paths to the root