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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Fungal Eye Infections
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Accession:DOID:9001949 term browser browse the term
Definition:Infection by a variety of fungi, usually through four possible mechanisms: superficial infection producing conjunctivitis, keratitis, or lacrimal obstruction; extension of infection from neighboring structures - skin, paranasal sinuses, nasopharynx; direct introduction during surgery or accidental penetrating trauma; or via the blood or lymphatic routes in patients with underlying mycoses.
Synonyms:exact_synonym: Fungal Ocular Infection;   Fungal Ocular Infections;   Ocular Mycoses;   Ocular Mycosis;   Ocular Mycotic Infection;   Ocular Mycotic Infections;   Oculomycoses;   fungal eye infection;   oculomycosis
 primary_id: MESH:D015821


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Fungal Eye Infections term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr2 toll-like receptor 2 IEP mRNA:increased expression:cornea RGD PMID:19474209 RGD:2312502 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr4 toll-like receptor 4 IEP mRNA:increased expression:cornea RGD PMID:19474209 RGD:2312502 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
Fungal Keratitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec7a C-type lectin domain containing 7A treatment ISO mRNA:increased expression:cornea RGD PMID:26963514 PMID:26963514 RGD:11526921, RGD:11526921 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Tlr4 toll-like receptor 4 ISO RGD PMID:20617171 RGD:7794847 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 treatment ISO mRNA:increased expression:cornea RGD PMID:26963514 PMID:26963514 PMID:26963514 RGD:11526921, RGD:11526921, RGD:11526921 NCBI chr 9:12,763,819...12,779,285
Ensembl chr 9:12,763,819...12,779,203 		JBrowse link
G Tslp thymic stromal lymphopoietin disease_progression ISO RGD PMID:29550278 PMID:30853520 RGD:38549371, RGD:38549574 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19050
    disease by infectious agent 2250
      Bacterial Infections and Mycoses 1116
        fungal infectious disease 162
          Fungal Eye Infections 5
            Fungal Keratitis 4
            suppurative uveitis + 0
Path 2
Term Annotations click to browse term
  disease 19050
    disease of anatomical entity 18384
      nervous system disease 14257
        Neurologic Manifestations 10336
          sensory system disease 7255
            eye disease 3731
              Eye Infections 59
                Fungal Eye Infections 5
                  Fungal Keratitis 4
                  suppurative uveitis + 0
paths to the root