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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Achlorhydria
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Accession:DOID:9001295 term browser browse the term
Definition:A lack of HYDROCHLORIC ACID in GASTRIC JUICE despite stimulation of gastric secretion.
Synonyms:exact_synonym: Achylia Gastrica;   Hypochlorhydria
 primary_id: MESH:D000126


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Achlorhydria term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 ISO DNA:deletion:exon (rat) RGD PMID:16368876 RGD:1581602 NCBI chr11:2,445,008...2,849,105
Ensembl chr11:2,444,654...2,849,105 		JBrowse link
G TFF1 trefoil factor 1 ISO protein:increased secretion:stomach RGD PMID:11903739 RGD:2292010 NCBI chr21:42,362,282...42,366,535
Ensembl chr21:42,362,282...42,366,535 		JBrowse link
G TLR9 toll like receptor 9 IAGP DNA:SNP:promoter:g.-1237T>C (rs5743836) (human) RGD PMID:20038537 RGD:5130741 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 97387
    Nutritional and Metabolic Diseases 13671
      disease of metabolism 13671
        Acid-Base Imbalance 186
          Achlorhydria 3
paths to the root