RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: Neoplasm Metastasis
Accession: DOID:9000965
browse the term
Definition: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.
Synonyms: exact_synonym: Metastases; Metastasis; Neoplasm Metastases
primary_id: MESH:D009362
xref: EFO:0009708 ; EFO:0009709 ; EFO:0010941
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Abcb1a
ATP binding cassette subfamily B member 1A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12015757
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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Abcc4
ATP binding cassette subfamily C member 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17003774
NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
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Ace
angiotensin I converting enzyme
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18059164
NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
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Ackr3
atypical chemokine receptor 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22180778
NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237
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Acsbg1
acyl-CoA synthetase bubblegum family member 1
ISO
associated with pheochromocytoma
RGD
PMID:29067245
RGD:13831131
NCBI chr 8:54,991,294...55,047,276
Ensembl chr 8:54,991,296...55,047,391
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Acvr2a
activin A receptor type 2A
exacerbates
ISO
associated with colon cancer;mRNA,protein:decreased expression:colon (human)
RGD
PMID:30310521
RGD:151361136
NCBI chr 3:33,204,961...33,292,673
Ensembl chr 3:33,205,523...33,289,968
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Adgrb1
adhesion G protein-coupled receptor B1
ISO
associated with colorectal cancer
RGD
PMID:9772287
RGD:13831353
NCBI chr 7:106,404,827...106,476,902
Ensembl chr 7:106,404,958...106,476,902
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Adora2b
adenosine A2B receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27590504
NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772
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Agtr1a
angiotensin II receptor, type 1a
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18059164
NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
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Agtr2
angiotensin II receptor, type 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18059164
NCBI chr X:112,119,876...112,124,060
Ensembl chr X:112,120,228...112,124,057
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Ahr
aryl hydrocarbon receptor
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:21948867
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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Akirin2
akirin 2
IMP
RGD
PMID:18460465
RGD:2306009
NCBI chr 5:49,108,231...49,122,566
Ensembl chr 5:49,108,220...49,122,568
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Akt2
AKT serine/threonine kinase 2
ISO
associated with Mammary Neoplasms, Experimental
RGD
PMID:19491266
RGD:2315599
NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
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Aldoa
aldolase, fructose-bisphosphate A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20562527
NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
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Alk
ALK receptor tyrosine kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22986231 PMID:22999080
NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034
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Alox5
arachidonate 5-lipoxygenase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20061081
NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
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Amigo2
adhesion molecule with Ig like domain 2
ISO
Liver Metastasis
RGD
PMID:28272394
RGD:14394499
NCBI chr 7:128,391,493...128,394,589
Ensembl chr 7:128,390,412...128,394,695
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Angptl4
angiopoietin-like 4
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:17130448
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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Antxr1
ANTXR cell adhesion molecule 1
ISO
associated with Mammary Neoplasms, Experimental;
RGD
PMID:22085271
RGD:9684855
NCBI chr 4:119,590,770...119,778,232
Ensembl chr 4:119,590,771...119,778,232
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Anxa1
annexin A1
treatment
IEP ISO IMP
associated with Mammary Neoplasms, Experimental;protein:increased expression:lung CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:20308542 PMID:9514092 PMID:20821804 PMID:20821804 PMID:20308542
RGD:2306939 , RGD:7421541 , RGD:7421541 , RGD:7421563
NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
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Anxa4
annexin A4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17085005
NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161
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Anxa7
annexin A7
ISO
associated with Breast Neoplasms;protein:increased expression:breast associated with Prostatic Neoplasms;protein:decreased expression:prostate gland
RGD
PMID:15073110 PMID:11287641
RGD:2292655 , RGD:2292656
NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385
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Apoe
apolipoprotein E
ISO
RGD
PMID:22469977
RGD:7771597
NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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Arhgdia
Rho GDP dissociation inhibitor alpha
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20562527
NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023
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Arid1a
AT-rich interaction domain 1A
disease_progression
ISO
in lung; associated with hepatocellular carcinoma
RGD
PMID:25975202
RGD:125097495
NCBI chr 5:145,908,173...145,981,552
Ensembl chr 5:145,908,181...145,985,564
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Atp6v1c1
ATPase H+ transporting V1 subunit C1
ISO
associated with Mammary Neoplasms, Experimental
RGD
PMID:24155661
RGD:14700647
NCBI chr 7:69,834,464...69,872,278
Ensembl chr 7:69,834,463...69,872,278
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Axl
Axl receptor tyrosine kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26206560
NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265
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Azin1
antizyme inhibitor 1
ISO
associated with stomach cancer;RNA:increased editing:stomach associated with colorectal cancer;RNA:increased editing:colorectum
RGD
PMID:30563560 PMID:29925690
RGD:14700703 , RGD:14700704
NCBI chr 7:69,654,773...69,681,578
Ensembl chr 7:69,654,663...69,681,578
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Bax
BCL2 associated X, apoptosis regulator
ISO
associated with Carcinoma, Infiltrating Duct
RGD
PMID:17288732
RGD:1643356
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bcl2
BCL2, apoptosis regulator
ISO
associated with Breast Neoplasms associated with Carcinoma, Renal Cell
RGD
PMID:16826579 PMID:12810203
RGD:2293020 , RGD:2293021
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bmp6
bone morphogenetic protein 6
severity
ISO
associated with Prostatic Neoplasms;protein:increased expression:bone
RGD
PMID:16166304
RGD:2289018
NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365
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Bmp7
bone morphogenetic protein 7
disease_progression
ISO
associated with Breast Neoplasms;protein:increased expression:breast associated with Prostatic Neoplasms;mRNA:increased expression:bone
RGD
PMID:17895257 PMID:12539225
RGD:2289029 , RGD:2289033
NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
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Braf
B-Raf proto-oncogene, serine/threonine kinase
onset
ISO
associated with Melanoma; DNA:mutations: :
RGD
PMID:25623140
RGD:11567259
NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
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Brd4
bromodomain containing 4
ISO
RGD
PMID:23950209
RGD:9586346
NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539
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Brms1
BRMS1, transcriptional repressor and anoikis regulator
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:27501413
NCBI chr 1:202,345,766...202,355,028
Ensembl chr 1:202,345,704...202,355,028
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Bsg
basigin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21956400
NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387
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Cab39
calcium binding protein 39
ISO
associated with hepatocellular carcinoma;
RGD
PMID:28605041
RGD:14398832
NCBI chr 9:86,463,095...86,524,545
Ensembl chr 9:86,463,095...86,524,544
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Cacybp
calcyclin binding protein
ISO
associated with pancreatic neoplasms
RGD
PMID:18765951
RGD:2326146
NCBI chr13:72,437,485...72,447,810
Ensembl chr13:72,437,490...72,450,177
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Calml3
calmodulin-like 3
ameliorates
ISO
associated with hepatocellular carcinoma; human cells in mouse model associated with hepatocellular carcinoma; protein:decreased expression:liver (human)
RGD
PMID:29445139 PMID:29445139
RGD:151665319 , RGD:151665319
NCBI chr17:66,419,844...66,423,083
Ensembl chr17:66,419,882...66,423,175
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Cap1
cyclase associated actin cytoskeleton regulatory protein 1
ISO
associated with Pancreatic Neoplasms; mRNA, protein:increased expression:pancreas
RGD
PMID:19188911
RGD:2326238
NCBI chr 5:135,142,108...135,168,885
Ensembl chr 5:135,142,112...135,168,769
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Casp3
caspase 3
ISO
associated with Breast Neoplasms
RGD
PMID:18064531
RGD:2293306
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Cat
catalase
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:12538496 PMID:22580338 PMID:23518002
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Cav1
caveolin 1
treatment
ISO
associated with Mammary Neoplasms, Experimental CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:20562527 PMID:15355971 PMID:15334058
RGD:2289106 , RGD:8661780
NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
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Cbx4
chromobox 4
ISO
associated with Carcinoma, Hepatocellular;
RGD
PMID:24838576
RGD:9586738
NCBI chr10:104,337,140...104,343,210
Ensembl chr10:104,336,876...104,356,706
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Cbx5
chromobox 5
ISO
associated with Lung Neoplasms;
RGD
PMID:22900142
RGD:9586743
NCBI chr 7:134,333,165...134,376,102
Ensembl chr 7:134,331,335...134,375,022
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Ccl2
C-C motif chemokine ligand 2
ISO
associated with Mammary Neoplasms, Experimental
RGD
PMID:19629725
RGD:4891450
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Ccl20
C-C motif chemokine ligand 20
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30603057
NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
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Ccl3
C-C motif chemokine ligand 3
ISO
RGD
PMID:18941229
RGD:7241810
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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Ccl5
C-C motif chemokine ligand 5
treatment
ISO
associated with Animal Mammary Neoplasms;
RGD
PMID:15692764
RGD:14995455
NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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Ccn4
cellular communication network factor 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30723155
NCBI chr 7:98,645,238...98,677,253
Ensembl chr 7:98,645,182...98,677,248
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Ccna2
cyclin A2
ISO
associated with Seminoma;protein:increased expression:testis
RGD
PMID:14696091
RGD:2293346
NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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Ccnd1
cyclin D1
treatment
ISO
associated with Carcinoma, Non-Small-Cell Lung;mRNA:splice variant associated with stomach cancer; human cells in mouse model
RGD
PMID:18715616 PMID:27431311
RGD:13434926 , RGD:152995400
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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Ccnd2
cyclin D2
ISO
associated with Breast Neoplasms;DNA:hypermethylated:brain
RGD
PMID:15131050
RGD:2289155
NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
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Ccne1
cyclin E1
disease_progression
ISO
protein:altered processing associated with non-small cell lung carcinoma
RGD
PMID:17671189 PMID:11212263
RGD:2289229 , RGD:13673913
NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
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Ccr5
C-C motif chemokine receptor 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:35072892
NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
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Cd274
CD274 molecule
disease_progression
ISO
associated with ovarian cancer
RGD
PMID:23340297
RGD:41410797
NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450
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Cd44
CD44 molecule
ISO
associated with Carcinoma, Renal Cell;protein:increased expression:kidney CTD Direct Evidence: marker/mechanism associated with Breast Neoplasm;protein:increased expression:liver
CTD RGD
PMID:23098472 PMID:18026989 PMID:17991717
RGD:2289347 , RGD:2289349
NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
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Cd82
Cd82 molecule
IEP ISO
associated with Carcinoma, Hepatocellular;mRNA:decreased expression CTD Direct Evidence: therapeutic associated with Prostatic Neoplasms;mRNA:decreased expression:bone associated with Carcinoma, Infiltrating Duct;mRNA:decreased expression:brain associated with Prostatic Neoplasms;DNA:loss of heterozygosity
CTD RGD
PMID:20075392 PMID:11275982 PMID:12806379 PMID:15592684 PMID:9831222 PMID:9254900 More...
RGD:2289407 , RGD:2289402 , RGD:2289400 , RGD:68869 , RGD:2289425
NCBI chr 3:79,387,361...79,431,847
Ensembl chr 3:79,385,887...79,431,809
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Cd86
CD86 molecule
IEP
mRNA:decreased expression:mediastinal lymph node (rat)
RGD
PMID:18360875
RGD:4892237
NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
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Cdh1
cadherin 1
treatment
ISO
associated with Prostatic Neoplasms associated with stomach cancer; human cells in mouse model CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:17520682 PMID:22580338 PMID:18008331 PMID:27431311
RGD:2289488 , RGD:152995400
NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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Cdh2
cadherin 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23876460
NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
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Cdkl2
cyclin dependent kinase like 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25333262
NCBI chr14:16,027,381...16,063,257
Ensembl chr14:16,028,363...16,063,252
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
ISO
associated with Melanoma;
RGD
PMID:9194578
RGD:8662817
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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Cdkn2a
cyclin-dependent kinase inhibitor 2A
ISO
associated with Paraganglioma, Extra-Adrenal;DNA:hypermethylation
RGD
PMID:18509008
RGD:8552280
NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
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Cfl1
cofilin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20562527
NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
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Cga
glycoprotein hormones, alpha polypeptide
ISO
associated with Breast Neoplasms;protein:increased expression:serum
RGD
PMID:6768680
RGD:2293637
NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
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Chek1
checkpoint kinase 1
ISO
associated with Pancreatic Neoplasms
RGD
PMID:15448002
RGD:2317235
NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
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Chuk
component of inhibitor of nuclear factor kappa B kinase complex
ISO
associated with prostate adenocarcinoma
RGD
PMID:17377533
RGD:2298657
NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
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Cic
capicua transcriptional repressor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27869830
NCBI chr 1:80,853,920...80,880,537
Ensembl chr 1:80,853,920...80,880,532
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Cldn7
claudin 7
IMP
RGD
PMID:23390083
RGD:9685143
NCBI chr10:54,689,684...54,692,177
Ensembl chr10:54,689,987...54,692,171
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Clic1
chloride intracellular channel 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20562527
NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712
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Clu
clusterin
ISO
associated with Breast Neoplasms
RGD
PMID:20307318
RGD:8883512
NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
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Creb1
cAMP responsive element binding protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:29179997
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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Csf1
colony stimulating factor 1
ISO
associated with Prostatic Neoplasms
RGD
PMID:18510570
RGD:2293638
NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
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Csf1r
colony stimulating factor 1 receptor
exacerbates
ISO
associated with Prostatic Neoplasms associated with breast cancer CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:1390197 PMID:18510570 PMID:25005824
RGD:2293638 , RGD:150524287
NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
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Csf3
colony stimulating factor 3
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:7543699 PMID:9018096
NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
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Cst3
cystatin C
ISO
protein:decreased expression:cerebrospinal fluid
RGD
PMID:12589965
RGD:5686394
NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
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Csta
cystatin A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20461718
NCBI chr11:64,620,483...64,631,488
Ensembl chr11:64,620,483...64,631,488
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Ctla4
cytotoxic T-lymphocyte-associated protein 4
disease_progression
ISO
associated with Mammary Neoplasms, Experimental
RGD
PMID:15701862 PMID:18049334
RGD:4891518 , RGD:7204722
NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963
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Ctnnb1
catenin beta 1
ISO
associated with Prostatic Neoplasms CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:29106415 PMID:18008331
RGD:2289488
NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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Ctsb
cathepsin B
ISO
protein:increased expression:cerebrospinal fluid
RGD
PMID:12589965
RGD:5686394
NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
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Ctsd
cathepsin D
ISO
protein:increased expression:oral cavity, oropharynx, hypopharynx (human)
RGD
PMID:10562684
RGD:1547892
NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
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Ctsh
cathepsin H
ISO
protein:increased expression:cerebrospinal fluid
RGD
PMID:12589965
RGD:5686394
NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824
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Ctu1
cytosolic thiouridylase subunit 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27811057
NCBI chr 1:94,115,431...94,121,224
Ensembl chr 1:94,115,420...94,121,221
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Ctu2
cytosolic thiouridylase subunit 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27811057
NCBI chr19:50,539,184...50,544,629
Ensembl chr19:50,539,352...50,544,623
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Cx3cr1
C-X3-C motif chemokine receptor 1
susceptibility
ISO
associated with Breast Neoplasms
RGD
PMID:16627550
RGD:4892015
NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
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Cxcl12
C-X-C motif chemokine ligand 12
treatment
ISO
associated with Pancreatic Neoplasms CTD Direct Evidence: marker/mechanism associated with Pancreatic Carcinoma
CTD RGD
PMID:21312072 PMID:23743303 PMID:12761880 PMID:26330165
RGD:2317610 , RGD:10398726
NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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Cxcr3
C-X-C motif chemokine receptor 3
ISO
associated with Mammary Neoplasms, Experimental
RGD
PMID:16885372
RGD:5135487
NCBI chr X:66,844,318...66,846,969
Ensembl chr X:66,844,318...66,846,969
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Cxcr4
C-X-C motif chemokine receptor 4
ameliorates severity disease_progression
ISO
CTD Direct Evidence: marker/mechanism associated with lung non-small cell carcinoma;mRNA,protein:increased expression:lung (human) associated with Otorhinolaryngologic Neoplasms;mRNA,protein:increased expression:Laryngeal and hypopharyngeal tissue (human) associated with lung non-small cell carcinoma; protein:increased expression:lung (human) associated with oral squamous cell carcinoma associated with pancreatic cancer associated with osteosarcoma;protein:increased expression:bone (human) human cells in mouse model;associated with lung cancer associated with lung cancer; human cells in mouse model
CTD RGD
PMID:21312072 PMID:23743303 PMID:26546437 PMID:16322285 PMID:18487224 PMID:28000861 PMID:17634424 PMID:16230077 PMID:24932250 PMID:25504108 PMID:32037613 More...
RGD:152023746 , RGD:152177479 , RGD:152177478 , RGD:152177476 , RGD:152177475 , RGD:152025556 , RGD:152023745 , RGD:152023741 , RGD:151708730
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
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Cyp19a1
cytochrome P450, family 19, subfamily a, polypeptide 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28112739
NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
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Dab2ip
DAB2 interacting protein
severity
ISO
associated with colorectal cancer;protein:decreased expression:colorectum (human)
RGD
PMID:26336990
RGD:11531913
NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280
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Dapk1
death associated protein kinase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17319784
NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991
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Daxx
death-domain associated protein
ISO
RGD
PMID:23539629
RGD:9587820
NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
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Dcn
decorin
ISO
associated with Breast Neoplasms
RGD
PMID:18688028
RGD:2311418
NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
G
Ddr1
discoidin domain receptor tyrosine kinase 1
severity
ISO
mRNA:increased expression:ovary (human) protein:increased expression:bone (human)
RGD
PMID:28743276 PMID:29039472
RGD:151347541 , RGD:151347601
NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468
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Ddr2
discoidin domain receptor tyrosine kinase 2
ameliorates
ISO
associated with melanoma;
RGD
PMID:24293323
RGD:150429711
NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363
G
Ddx3x
DEAD-box helicase 3, X-linked
ISO
human cells in mouse model
RGD
PMID:26087195
RGD:11096798
NCBI chr X:9,479,532...9,493,169
Ensembl chr X:9,479,532...9,493,168
G
Dek
DEK proto-oncogene
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27811057
NCBI chr17:17,580,804...17,602,825
Ensembl chr17:17,580,843...17,602,808
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Dhfr
dihydrofolate reductase
disease_progression
IEP ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:19159907 PMID:8149482
RGD:11040442
NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
G
Dio3
iodothyronine deiodinase 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26825960
NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660
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Dmd
dystrophin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:24793134
NCBI chr X:47,272,324...49,504,219
Ensembl chr X:47,272,331...49,504,207
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Dnmt3b
DNA methyltransferase 3 beta
ISO
associated with Uterine Cervical Neoplasms;
RGD
PMID:22330137
RGD:9589117
NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124
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Dpyd
dihydropyrimidine dehydrogenase
treatment
ISO
associated with Colonic Neoplasms CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:17611699 PMID:11383214
RGD:11251755
NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
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E2f1
E2F transcription factor 1
severity
ISO
protein:increased expression:bone (human)
RGD
PMID:29039472
RGD:151347601
NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
G
E2f8
E2F transcription factor 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27683099
NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098
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Edn1
endothelin 1
ISO
RGD
PMID:12941866
RGD:734914
NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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Ednra
endothelin receptor type A
ISO
associated with Bladder Neoplasms
RGD
PMID:21183790
RGD:4892282
NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
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Eef1b2
eukaryotic translation elongation factor 1 beta 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17085005 PMID:20562527
NCBI chr 9:64,580,163...64,582,737
Ensembl chr 9:64,579,893...64,582,737
G
Eef2
eukaryotic translation elongation factor 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20562527
NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
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Efnb2
ephrin B2
ISO
associated with cholangiocarcinoma;protein:increased expression:biliary ductule (human)
RGD
PMID:25012246
RGD:153305948
NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391
G
Egf
epidermal growth factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21942447 PMID:23064031
NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
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Egfr
epidermal growth factor receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17369752 PMID:17575224 PMID:23867902
NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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Ehmt2
euchromatic histone lysine methyltransferase 2
ISO
associated with lung neoplasms; CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:20940408 PMID:25115793 PMID:20940408
RGD:9589170
NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547
G
Eif1ax
eukaryotic translation initiation factor 1A, X-linked
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17085005
NCBI chr X:35,498,698...35,513,402
Ensembl chr X:35,498,517...35,513,335
G
Eif4a2
eukaryotic translation initiation factor 4A2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17085005
NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781
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Elp3
elongator acetyltransferase complex subunit 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27811057
NCBI chr15:39,754,635...39,816,482
Ensembl chr15:39,754,632...39,816,445
G
Eml4
EMAP like 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22986231 PMID:22999080
NCBI chr 6:11,219,545...11,334,824
Ensembl chr 6:11,219,566...11,334,879
G
Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26037280
NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
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Epcam
epithelial cell adhesion molecule
IMP
RGD
PMID:23390083
RGD:9685143
NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
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Epo
erythropoietin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16699298
NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
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Epor
erythropoietin receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16699298
NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257
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Erbb2
erb-b2 receptor tyrosine kinase 2
IMP ISO
rat gene in a mouse model CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:16984552 PMID:11238891
RGD:734938
NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
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Erbb3
erb-b2 receptor tyrosine kinase 3
disease_progression
ISO
associated with Prostatic Neoplasms;protein:alternative form associated with lung adenocarcinoma CTD Direct Evidence: marker/mechanism associated with Prostatic Neoplasms;protein:increased expression, altered localization:bone, nucleus
CTD RGD
PMID:28114269 PMID:18559590 PMID:26254096 PMID:17634423
RGD:2298500 , RGD:126790470 , RGD:2289944
NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525
G
Erbb4
erb-b2 receptor tyrosine kinase 4
disease_progression
ISO
associated with lung adenocarcinoma
RGD
PMID:26254096
RGD:126790470
NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
G
Ercc1
ERCC excision repair 1, endonuclease non-catalytic subunit
disease_progression
ISO
associated with Melanoma CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:20801905 PMID:26202595
RGD:11252177
NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
G
Ercc4
ERCC excision repair 4, endonuclease catalytic subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20372803
NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369
G
Erp29
endoplasmic reticulum protein 29
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17085005
NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
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Esr1
estrogen receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20104649 PMID:35044086
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
G
Etv4
ETS variant transcription factor 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27869830
NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974
G
Ezh2
enhancer of zeste 2 polycomb repressive complex 2 subunit
ISO
associated with stomach cancer;protein:increased expression:stomach associated with osteosarcoma associated with lung non-small cell carcinoma
RGD
PMID:20132185 PMID:26265454 PMID:24097870
RGD:126779607 , RGD:11532507 , RGD:126781716
NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
G
Ezr
ezrin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27137931
NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
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F2
coagulation factor II, thrombin
ISO
associated with Carcinoma, Small cell;protein:increased expression:brain
RGD
PMID:22065054
RGD:6893520
NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
G
Fadd
Fas associated via death domain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16450001
NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
G
Fas
Fas cell surface death receptor
ISO
associated with Breast Neoplasms;protein:decreased expression:breast associated with Mammary Neoplasms;protein:decreased expression:lung
RGD
PMID:17352235 PMID:17918178
RGD:2290053 , RGD:2290048
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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Faslg
Fas ligand
ISO
associated with Breast Neoplasms;protein:decreased expression:breast
RGD
PMID:17352235
RGD:2290053
NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
G
Fgf13
fibroblast growth factor 13
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19917848
NCBI chr X:137,276,498...137,800,056
Ensembl chr X:137,276,511...137,800,391
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Fgfr1
Fibroblast growth factor receptor 1
ISO
associated with prostate adenocarcinoma
RGD
PMID:23576558
RGD:13504748
NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350
G
Flt1
Fms related receptor tyrosine kinase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21975929
NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
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Fn1
fibronectin 1
treatment
ISO
associated with stomach cancer; human cells in mouse model
RGD
PMID:27431311
RGD:152995400
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
G
Fscn1
fascin actin-bundling protein 1
ISO
associated with Pancreatic Neoplasms
RGD
PMID:15626919
RGD:2317788
NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211
G
Ftl1
ferritin light chain 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17085005
NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725 Ensembl chr10:95,936,387...95,939,725
G
Gab2
GRB2-associated binding protein 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21996746
NCBI chr 1:151,429,844...151,625,708
Ensembl chr 1:151,429,695...151,625,031
G
Gdf15
growth differentiation factor 15
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23996089
NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
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Gjb1
gap junction protein, beta 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17978847
NCBI chr X:66,501,848...66,509,783
Ensembl chr X:66,501,820...66,509,925
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Gp1ba
glycoprotein Ib platelet subunit alpha
ISO
associated with Melanoma, Experimental
RGD
PMID:19727118
RGD:10450866
NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774
G
Gpcpd1
glycerophosphocholine phosphodiesterase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25482527
NCBI chr 3:119,787,681...119,832,550
Ensembl chr 3:119,787,682...119,832,517
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Gpi
glucose-6-phosphate isomerase
ISO
RGD
PMID:20978190
RGD:11051956
NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086
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Gpx2
glutathione peroxidase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23867582
NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
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Habp2
hyaluronan binding protein 2
treatment
IMP
associated with Thyroid Neoplasms
RGD
PMID:22715430
RGD:11353856
NCBI chr 1:255,315,870...255,350,161
Ensembl chr 1:255,315,915...255,350,160
G
Havcr2
hepatitis A virus cellular receptor 2
disease_progression
ISO
DNA:polymorphisms: : +4259T>G (human)
RGD
PMID:22472081
RGD:7245505
NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137
G
Hdac3
histone deacetylase 3
ISO
associated with Anaphylaxis; CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:34973135 PMID:24619412
RGD:9590165
NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856
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Hgf
hepatocyte growth factor
ISO
associated with Pancreatic Neoplasms CTD Direct Evidence: marker/mechanism associated with Mammary Neoplasms, Experimental; associated with Melanoma;
CTD RGD
PMID:25971889 PMID:11893931 PMID:16459153 PMID:10688652
RGD:2317904 , RGD:8548625 , RGD:8548538
NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
G
Hpse
heparanase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22240343
NCBI chr14:8,896,593...8,937,011
Ensembl chr14:8,896,593...8,937,010
G
Hrh2
histamine receptor H 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:6224980
NCBI chr17:10,366,004...10,407,791
Ensembl chr17:10,368,298...10,407,631
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Hsp90aa1
heat shock protein 90 alpha family class A member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20562527
NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
G
Hspa1a
heat shock protein family A (Hsp70) member 1A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26984758
NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
G
Ibsp
integrin-binding sialoprotein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22407340 PMID:24980816
NCBI chr14:5,439,825...5,452,570
Ensembl chr14:5,439,829...5,452,693
G
Icam1
intercellular adhesion molecule 1
ISO
associated with Pancreatic Neoplasms;protein:increased expression:serum associated with Melanoma, Cutaneous Malignant
RGD
PMID:12923961 PMID:10465581
RGD:2325163 , RGD:8547593
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
G
Id1
inhibitor of DNA binding 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:24910342
NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
G
Igf1
insulin-like growth factor 1
ISO
associated with Pancreatic Neoplasms CTD Direct Evidence: marker/mechanism associated with Uveal Melanoma;protein:increased expression:serum:
CTD RGD
PMID:18398872 PMID:19375852 PMID:23197685
RGD:2317643 , RGD:8548834
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
G
Igf1r
insulin-like growth factor 1 receptor
ISO
associated with Pancreatic Neoplasms
RGD
PMID:16575403
RGD:2317645
NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
G
Igf2
insulin-like growth factor 2
ISO
associated with Arthritis, Experimental; protein:increased expression:lung, bone, serum:
RGD
PMID:21859454
RGD:5510000
NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
G
Ikzf1
IKAROS family zinc finger 1
ISO
associated with colorectal cancer;DNA:polymorphisms:
RGD
PMID:31320627
RGD:150540328
NCBI chr14:86,255,065...86,340,839
Ensembl chr14:86,255,065...86,342,416
G
Il10
interleukin 10
ISO
RGD
PMID:16035616
RGD:1598627
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
G
Il18
interleukin 18
ISO
protein:increased expression:serum CTD Direct Evidence: marker/mechanism associated with breast cancer;DNA:SNP:promoter:-137G>C (rs187238) (human) associated with breast cancer;protein:increased expression:serum
CTD RGD
PMID:12748951 PMID:11215816 PMID:19152241 PMID:12209760
RGD:4889862 , RGD:8655899 , RGD:8655866
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
G
Il2
interleukin 2
treatment
ISO
associated with melanoma; associated with neuroblastoma. CTD Direct Evidence: therapeutic
CTD RGD
PMID:17105418 PMID:8610104 PMID:9362156 PMID:8642346
RGD:8663438 , RGD:14865005 , RGD:14747043
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
G
Il6
interleukin 6
treatment
ISO
associated with stomach cancer, human cells in mouse model CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:21937440 PMID:26101800 PMID:28186964
RGD:127229952
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Itga6
integrin subunit alpha 6
IEP
RGD
PMID:13130099
RGD:1302259
NCBI chr 3:56,604,512...56,689,428
Ensembl chr 3:56,617,268...56,689,428
G
Itgb1
integrin subunit beta 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23562787
NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
G
Itgb3
integrin subunit beta 3
ISO
mRNA, protein:increased expression:lung associated with renal cell carcinoma;DNA:missense mutation:cds:p.L33P (human)
RGD
PMID:21107114 PMID:16831169
RGD:5037225 , RGD:6907406
NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
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Jak2
Janus kinase 2
treatment
ISO
associated with stomach cancer, human cells in mouse model
RGD
PMID:28186964
RGD:127229952
NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
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Jup
junction plakoglobin
ISO
associated with Ovarian Neoplasms
RGD
PMID:15619205
RGD:2301746
NCBI chr10:85,300,438...85,327,378
Ensembl chr10:85,300,440...85,327,057
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Kdm6a
lysine demethylase 6A
disease_progression
ISO
associated with lung adenocarcinoma;protein:increased expression:brain (human)
RGD
PMID:33291558
RGD:150429741
NCBI chr X:4,337,466...4,477,100
Ensembl chr X:4,337,750...4,477,062
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Kdr
kinase insert domain receptor
ISO
associated with Carcinoma, Renal Cell
RGD
PMID:17465216
RGD:2301757
NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
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Kif2c
kinesin family member 2C
disease_progression
ISO
associated with colorectal cancer
RGD
PMID:18506187
RGD:27372891
NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637
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Kiss1
KiSS-1 metastasis-suppressor
ISO
associated with Ovarian Neoplasms
RGD
PMID:16283480
RGD:2298668
NCBI chr13:44,775,106...44,780,707
Ensembl chr13:44,774,823...44,780,612
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Kmt2b
lysine methyltransferase 2B
ISO
associated with lung adenocarcinoma
RGD
PMID:33291558
RGD:150429741
NCBI chr 1:85,821,700...85,840,987
Ensembl chr 1:85,821,753...85,841,326
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Kmt2d
lysine methyltransferase 2D
disease_progression
ISO
associated with colorectal cancer;DNA:mutations::
RGD
PMID:27875625
RGD:155582219
NCBI chr 7:129,980,744...130,022,088
Ensembl chr 7:129,962,887...130,020,325
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Kras
KRAS proto-oncogene, GTPase
treatment disease_progression
ISO
CTD Direct Evidence: marker/mechanism associated with stomach cancer; human cells in mouse model associated with colorectal cancer; DNA:mutation:cds: associated with colorectal cancer;DNA:mutations: : associated with colorectal cancer;DNA:mutation: : associated with Fibrosarcoma;mRNA,protein:decreased expression::
CTD RGD
PMID:8635384 PMID:27431311 PMID:27264476 PMID:26210240 PMID:29032374 PMID:3552201 More...
RGD:152995400 , RGD:14398751 , RGD:11086960 , RGD:14398745 , RGD:11570402
NCBI chr 4:178,185,418...178,218,484
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Krt14
keratin 14
IEP
mRNA:decreased expression:epithelial cell
RGD
PMID:9876218
RGD:1600180
NCBI chr10:85,137,786...85,142,054
Ensembl chr10:85,066,802...85,171,799
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Krt20
keratin 20
ISO
associated with Colorectal Neoplasms
RGD
PMID:10931219
RGD:2317676
NCBI chr10:84,384,790...84,394,125
Ensembl chr10:84,384,802...84,394,107
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L1cam
L1 cell adhesion molecule
treatment
ISO
associated with Pancreatic Neoplasms; associated with Lung Neoplasms;
RGD
PMID:22095073 PMID:22307136
RGD:11570404 , RGD:11570503
NCBI chr X:151,597,270...151,623,776
Ensembl chr X:151,597,277...151,623,857
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Lamc2
laminin subunit gamma 2
ISO
associated with lung adenocarcinoma;
RGD
PMID:25591736
RGD:11075980
NCBI chr13:65,284,664...65,344,164
Ensembl chr13:65,284,664...65,344,200
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Lcn2
lipocalin 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:24570342
NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
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Lect2
leukocyte cell-derived chemotaxin 2
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:30453282
NCBI chr17:8,044,759...8,050,983
Ensembl chr17:8,044,759...8,050,983
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Lef1
lymphoid enhancer binding factor 1
ISO
associated with prostate cancer CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:27811057 PMID:27067790
RGD:11531513
NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794
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Lgals3
galectin 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25882088
NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
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Llgl2
LLGL scribble cell polarity complex component 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28114269
NCBI chr10:101,050,978...101,086,527
Ensembl chr10:101,051,408...101,086,525
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Ly96
lymphocyte antigen 96
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22180778
NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386
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Macc1
MET transcriptional regulator MACC1
treatment
ISO
associated with stomach cancer; human cells in mouse model CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:36008464 PMID:27431311
RGD:152995400
NCBI chr 6:140,352,690...140,430,255
Ensembl chr 6:140,352,755...140,430,255
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Map2k4
mitogen activated protein kinase kinase 4
disease_progression
ISO
associated with oral squamous cell carcinoma;mRNA, protein:increased expression:lymph node (human)
RGD
PMID:22165133
RGD:150429749
NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
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Mapk1
mitogen activated protein kinase 1
treatment
ISO
CTD Direct Evidence: marker/mechanism associated with prostate adenocarcinoma
CTD RGD
PMID:22580338 PMID:22139534
RGD:13504820
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk3
mitogen activated protein kinase 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22580338
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Mapk9
mitogen-activated protein kinase 9
ISO
CTD Direct Evidence: therapeutic associated with Colorectal Neoplasms
CTD RGD
PMID:21779479 PMID:25205654
RGD:13217416
NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
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Med28
mediator complex subunit 28
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21942447
NCBI chr14:65,594,785...65,603,583
Ensembl chr14:65,594,647...65,603,583
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Met
MET proto-oncogene, receptor tyrosine kinase
disease_progression
ISO
associated with Squamous Cell Carcinoma of the Tongue; CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:20080979 PMID:21225626 PMID:22704061
RGD:8548616
NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
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Mir100
microRNA 100
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19487542
NCBI chr 8:41,901,225...41,901,304
Ensembl chr 8:41,901,225...41,901,304
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Mir106a
microRNA 106a
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19487542
NCBI chr X:132,422,584...132,422,661
Ensembl chr X:132,422,584...132,422,661
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Mir125a
microRNA 125a
ISO
CTD Direct Evidence: marker/mechanism associated with stomach cancer;
CTD RGD
PMID:19487542 PMID:30117667
RGD:21403678
NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710
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Mir130a
microRNA 130a
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19487542
NCBI chr 3:69,822,542...69,822,629
Ensembl chr 3:69,822,542...69,822,629
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Mir130b
microRNA 130b
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19487542
NCBI chr11:83,880,163...83,880,244
Ensembl chr11:83,880,163...83,880,244
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Mir136
microRNA 136
ameliorates
ISO
associated with stomach cancer;human cells in mouse model
RGD
PMID:28656883
RGD:153344628
NCBI chr 6:128,549,096...128,549,177
Ensembl chr 6:128,549,096...128,549,177
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Mir148b
microRNA 148b
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19487542
NCBI chr 7:134,421,398...134,421,494
Ensembl chr 7:134,421,398...134,421,494
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Mir152
microRNA 152
ISO
associated with Castration-Resistant Prostatic Neoplasms
RGD
PMID:23574937
RGD:19165145
NCBI chr10:81,832,936...81,833,020
Ensembl chr10:81,832,936...81,833,020
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Mir155
microRNA 155
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:19487542 PMID:27692344 PMID:27856635
RGD:21079446
NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
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Mir181c
microRNA 181c
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19487542
NCBI chr19:23,983,523...23,983,628
Ensembl chr19:23,983,523...23,983,628
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Mir181d
microRNA 181d
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19487542
NCBI chr19:23,983,706...23,983,788
Ensembl chr19:23,983,706...23,983,788
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Mir193a
microRNA 193a
exacerbates
ISO
associated with lung non-small cell carcinoma; human cells in mouse model
RGD
PMID:24469061 PMID:30685413
RGD:153344592 , RGD:153344599
NCBI chr10:64,672,343...64,672,454
Ensembl chr10:64,672,343...64,672,454
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Mir19a
microRNA 19a
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19487542
NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993
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Mir205
microRNA 205
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19487542
NCBI chr13:105,035,878...105,035,985
Ensembl chr13:105,035,878...105,035,985
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Mir20a
microRNA 20a
ISO
associated with colorectal cancer
RGD
PMID:27286257
RGD:25823157
NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168
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Mir20b
microRNA 20b
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19487542
NCBI chr X:132,422,211...132,422,282
Ensembl chr X:132,422,211...132,422,282
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Mir21
microRNA 21
treatment ameliorates
ISO
associated with prostate carcinoma; human cells in mouse model CTD Direct Evidence: marker/mechanism human cells in mouse model;associated with breast cancer
CTD RGD
PMID:26101800 PMID:32736696 PMID:18270520
RGD:152998873 , RGD:152998897
NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
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Mir221
microRNA 221
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19487542
NCBI chr X:3,429,465...3,429,573
Ensembl chr X:3,429,465...3,429,573
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Mir222
microRNA 222
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19487542
NCBI chr X:3,428,904...3,429,006
Ensembl chr X:3,428,904...3,429,006
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Mir224
microRNA 224
ISO
CTD Direct Evidence: marker/mechanism associated with colorectal cancer; mRNA:increased expression:colorectal mucosa:
CTD RGD
PMID:19487542 PMID:25919696
RGD:14398749
NCBI chr X:150,065,088...150,065,169
Ensembl chr X:150,065,088...150,065,169
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Mir30a
microRNA 30a
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19487542
NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670
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Mir30e
microRNA 30e
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19487542
NCBI chr 5:134,352,232...134,352,323
Ensembl chr 5:134,352,232...134,352,323
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Mir31
microRNA 31
disease_progression treatment
ISO
CTD Direct Evidence: marker/mechanism associated with colorectal cancer;RNA:increased expression:colorectum (human) associated with stomach cancer;human cells in mouse model
CTD RGD
PMID:19487542 PMID:26497852 PMID:27174918 PMID:30108104
RGD:153297806 , RGD:153297811 , RGD:153297776
NCBI chr 5:103,599,038...103,599,143
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Mir342
microRNA 342
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19487542
NCBI chr 6:127,565,269...127,565,367
Ensembl chr 6:127,565,269...127,565,367
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Mir346
microRNA 346
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27501413 PMID:27777383
NCBI chr16:10,218,118...10,218,215
Ensembl chr16:10,218,118...10,218,215
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Mir34b
microRNA 34b
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19487542
NCBI chr 8:51,410,244...51,410,327
Ensembl chr 8:51,410,244...51,410,327
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Mir34c
microRNA 34c
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19487542
NCBI chr 8:51,409,726...51,409,802
Ensembl chr 8:51,409,726...51,409,802
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Mir370
microRNA 370
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19487542
NCBI chr 6:128,572,257...128,572,335
Ensembl chr 6:128,572,257...128,572,335
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Mir494
microRNA 494
ISO
associated with osteosarcoma; RNA:decreased expression:bone, serum
RGD
PMID:30314946 PMID:35117781
RGD:156420141 , RGD:156430319
NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793
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Mir503
microRNA 503
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19487542
NCBI chr X:132,806,303...132,806,373
Ensembl chr X:132,806,303...132,806,373
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Mir532
microRNA 532
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19487542
NCBI chr X:15,247,315...15,247,393
Ensembl chr X:15,247,315...15,247,393
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Mir96
microRNA 96
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19487542
NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516
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Mir99a
microRNA 99a
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19487542
NCBI chr11:16,200,443...16,200,523
Ensembl chr11:16,200,443...16,200,523
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Mir99b
microRNA 99b
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19487542
NCBI chr 1:58,677,015...58,677,084
Ensembl chr 1:58,677,011...58,677,090
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Mki67
marker of proliferation Ki-67
ISO
associated with Pancreatic Neoplasms
RGD
PMID:20388395
RGD:2317702
NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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Mlh1
mutL homolog 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17717427
NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
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Mmp1
matrix metallopeptidase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12538496 PMID:19487542 PMID:22580338 PMID:23548910
NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
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Mmp10
matrix metallopeptidase 10
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22022614
NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748
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Mmp13
matrix metallopeptidase 13
ISO
associated with Carcinoma, Renal Cell;mRNA, protein:increased expression:bone
RGD
PMID:18709334
RGD:2306080
NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
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Mmp2
matrix metallopeptidase 2
disease_progression
ISO IEP
associated with Gallbladder Neoplasms; protein:increased expression:gallbladder associated with pancreatic cancer; protein:increased expression, increased activity:pancreas CTD Direct Evidence: marker/mechanism associated with Mammary Neoplasms, Animal;protein:increased expression:brain
RGD CTD
PMID:12173379 PMID:16475674 PMID:18398872 PMID:21209944 PMID:22321834 PMID:23707804 PMID:30603057 PMID:18665467 PMID:16158251 PMID:12173379 More...
RGD:2325749 , RGD:2325743 , RGD:8547884 , RGD:2325749
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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Mmp24
matrix metallopeptidase 24
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27869830
NCBI chr 3:144,279,096...144,323,572
Ensembl chr 3:144,279,096...144,323,572
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Mmp3
matrix metallopeptidase 3
IEP
associated with Mammary Neoplasms, Animal;protein:increased expression:brain
RGD
PMID:16158251
RGD:8547884
NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
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Mmp9
matrix metallopeptidase 9
severity disease_progression
ISO IMP IEP
associated with pancreatic cancer; protein:increased expression, increased activity:pancreas CTD Direct Evidence: marker/mechanism associated with osteosarcoma;protein:increased expression:bone (human) associated with skin melanoma;DNA:missense mutation:cds:p.Q279R (human) associated with Mammary Neoplasms, Animal;protein:increased expression:brain associated with Melanoma associated with Mammary Neoplasms, Animal; associated with Arthritis, Experimental associated with carcinoma, pancreatic ductal; protein:increased expression:pancreas
CTD RGD
PMID:15659795 PMID:16475674 PMID:18930813 PMID:21209944 PMID:21942447 PMID:26546437 PMID:34626302 PMID:12173379 PMID:8912869 PMID:17346338 PMID:16158251 PMID:18676849 PMID:16033831 PMID:21859454 PMID:17378244 More...
RGD:152023746 , RGD:2325749 , RGD:8547928 , RGD:8547886 , RGD:8547884 , RGD:8547878 , RGD:8547861 , RGD:5510000 , RGD:2325855
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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Msh2
mutS homolog 2
ISO
associated with Breast Neoplasms
RGD
PMID:17390069
RGD:2293506
NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
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Mst1
macrophage stimulating 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28114269
NCBI chr 8:108,767,886...108,773,425
Ensembl chr 8:108,768,839...108,773,416
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Mtdh
metadherin
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:19111877
NCBI chr 7:65,306,464...65,365,647
Ensembl chr 7:65,306,400...65,364,413
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Mthfr
methylenetetrahydrofolate reductase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17704422
NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
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Mtor
mechanistic target of rapamycin kinase
IMP
associated with Pancreatic Neoplasms
RGD
PMID:23149918
RGD:10040959
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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Muc1
mucin 1, cell surface associated
disease_progression
ISO
associated with Pancreatic Neoplasms associated with Carcinoma, Renal Cell;
RGD
PMID:16707592 PMID:10390012 PMID:12941828
RGD:2324648 , RGD:7245968 , RGD:2324652
NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733
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Muc4
mucin 4, cell surface associated
IMP
associated with Melanoma
RGD
PMID:10918186
RGD:2303746
NCBI chr11:68,008,245...68,053,242
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Muc5ac
mucin 5AC, oligomeric mucus/gel-forming
ISO
associated with chloangiocarcinoma;protein:increased expression:bile duct
RGD
PMID:16124042
RGD:2324987
NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475
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Muc6
mucin 6, oligomeric mucus/gel-forming
disease_progression
ISO
associated with cholangiocarcinoma
RGD
PMID:18410610
RGD:2325159
NCBI chr 1:196,726,678...196,764,842
Ensembl chr 1:196,726,807...196,764,842
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Myc
MYC proto-oncogene, bHLH transcription factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22321834
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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Mylk
myosin light chain kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12970723 PMID:18710790
NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261
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Nagk
N-acetylglucosamine kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17085005
NCBI chr 4:116,281,179...116,293,870
Ensembl chr 4:116,281,328...116,313,137
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Ncoa1
nuclear receptor coactivator 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21080969
NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664
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Ndc80
NDC80 kinetochore complex component
disease_progression
ISO
associated with melanoma
RGD
PMID:31173190
RGD:40822820
NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924
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Ndrg1
N-myc downstream regulated 1
ISO
CTD Direct Evidence: marker/mechanism|therapeutic
CTD
PMID:15867226 PMID:22972152
NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
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Nectin2
nectin cell adhesion molecule 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:29321541
NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360
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Nfe2l2
NFE2 like bZIP transcription factor 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:32682831
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nfkb1
nuclear factor kappa B subunit 1
ISO
associated with prostate cancer
RGD
PMID:17974971
RGD:13506764
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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Nfkbia
NFKB inhibitor alpha
ISO
associated with prostate cancer;protein:increased serine phosphorylation
RGD
PMID:23093296
RGD:13506767
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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Nme1
NME/NM23 nucleoside diphosphate kinase 1
ISO
associated with Ovarian Neoplasms CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:15928304 PMID:7622307
RGD:2299069
NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408
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Nme2
NME/NM23 nucleoside diphosphate kinase 2
resistance
IMP
RGD
PMID:8621239
RGD:2299081
NCBI chr10:78,898,097...78,903,514
Ensembl chr10:78,897,770...78,903,538
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Nos2
nitric oxide synthase 2
disease_progression
ISO
associated with Gallbladder Neoplasms: protein:increased expression:gallbladder associated with Carcinoma, Pancreatic Ductal associated with Carcinoma, Pancreatic Ductal; protein:increased expression:pancreas
RGD
PMID:14991947 PMID:12660813 PMID:15222037
RGD:2325250 , RGD:2325254 , RGD:2325242
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Nos3
nitric oxide synthase 3
susceptibility
ISO
protein:increased expression:blood vessel endothelial cell associated with Prostatic Neoplasms;DNA:polymorphism associated with Breast Neoplasms;DNA:polymorphism:promoter:-786T>C (human)
RGD
PMID:14672505 PMID:12445681 PMID:14623178
RGD:2292080 , RGD:2292087 , RGD:2292081
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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Nppa
natriuretic peptide A
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:18717826
NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
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Nsun6
NOP2/Sun RNA methyltransferase 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28114269
NCBI chr17:77,912,374...77,955,694
Ensembl chr17:77,912,377...77,950,006
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Ogn
osteoglycin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17085005
NCBI chr17:15,032,069...15,052,626
Ensembl chr17:15,032,069...15,052,739
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Olig2
oligodendrocyte transcription factor 2
ISO
associated with breast cancer
RGD
PMID:27340107
RGD:40902824
NCBI chr11:30,475,510...30,478,886
Ensembl chr11:30,475,398...30,480,152
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Orai1
ORAI calcium release-activated calcium modulator 1
treatment
ISO
associated with stomach cancer; human cells in mouse model
RGD
PMID:27431311
RGD:152995400
NCBI chr12:33,533,151...33,548,361
Ensembl chr12:33,534,344...33,548,405
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Osm
oncostatin M
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21937440
NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313
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Pcna
proliferating cell nuclear antigen
ISO
associated with Seminoma
RGD
PMID:9143022
RGD:2315011
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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Pde5a
phosphodiesterase 5A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12972520
NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
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Pdgfb
platelet derived growth factor subunit B
ISO
associated with Breast Neoplasms;mRNA, protein:increased expression:breast
RGD
PMID:16596190
RGD:2292179
NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
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Pdgfrb
platelet derived growth factor receptor beta
ISO
associated with Carcinoma, Renal Cell mRNA,protein:increased expression: :
RGD
PMID:15994946 PMID:14593398
RGD:2292198 , RGD:13703041
NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
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Pebp1
phosphatidylethanolamine binding protein 1
ISO
associated with Prostatic Neoplasms;protein:decreased expression:
RGD
PMID:12813171
RGD:2302862
NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
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Pik3c2b
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21986133
NCBI chr13:44,494,673...44,555,663
Ensembl chr13:44,495,050...44,555,612
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Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
treatment
ISO
CTD Direct Evidence: marker/mechanism associated with colorectal cancer;DNA:mutations::
CTD RGD
PMID:29106415 PMID:23302486
RGD:14402409
NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
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Pik3r3
phosphoinositide-3-kinase regulatory subunit 3
ISO
associated with Adenocarcinoma, Colon
RGD
PMID:24837077
RGD:13432045
NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583
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Plau
plasminogen activator, urokinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16475674
NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
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Plaur
plasminogen activator, urokinase receptor
ISO
associated with Ovarian Neoplasms CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:15659795 PMID:22577342
RGD:6483788
NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595
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Plod2
procollagen lysine, 2-oxoglutarate 5-dioxygenase 2
ameliorates
ISO
associated with lung non-small cell carcinoma
RGD
PMID:29072684
RGD:151665822
NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255
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Pml
PML nuclear body scaffold
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:29335545
NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
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Pms2
PMS1 homolog 2, mismatch repair system component
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17717427
NCBI chr12:10,676,818...10,701,161
Ensembl chr12:10,676,764...10,701,066
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Ppia
peptidylprolyl isomerase A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21956400
NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
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Prnp
prion protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17387271
NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
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Prox1
prospero homeobox 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17415710
NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183
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Prss8
serine protease 8
ISO
associated with Prostatic Neoplasms;mRNA:decreased expression:prostate gland, bone
RGD
PMID:12518323
RGD:2292484
NCBI chr 1:182,536,229...182,540,745
Ensembl chr 1:182,536,229...182,540,815
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Ptch1
patched 1
ISO
associated with colorectal cancer
RGD
PMID:20230186
RGD:150523835
NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333
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Pten
phosphatase and tensin homolog
ISO
associated with Mammary Neoplasms, Experimental CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:10978354 PMID:18381417
RGD:2292496
NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
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Ptgis
prostaglandin I2 synthase
exacerbates
ISO
associated with colorectal cancer; protein:increased expression:colorectum (human)
RGD
PMID:22109564
RGD:151347833
NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451
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Ptgs2
prostaglandin-endoperoxide synthase 2
IMP ISO
associated with Mammary Neoplasms, Experimental CTD Direct Evidence: marker/mechanism associated with osteosarcoma; associated with breast neoplasm; associated with lung neoplasm associated with Breast Neoplasms
CTD RGD
PMID:16489006 PMID:18509974 PMID:18398660 PMID:18797196 PMID:19421193 PMID:21238650 PMID:18663571 More...
RGD:2300249 , RGD:5135500 , RGD:5135498 , RGD:5135282 , RGD:2300119
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Ptk2
protein tyrosine kinase 2
ISO IMP
associated with Mammary Neoplasms, Experimental
RGD
PMID:16547501 PMID:15930288
RGD:2292557 , RGD:2292560
NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
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Pxn
paxillin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18492274
NCBI chr12:41,060,791...41,107,952
Ensembl chr12:41,060,791...41,107,931
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Rac1
Rac family small GTPase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18506888
NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
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Rad52
RAD52 homolog, DNA repair protein
susceptibility
ISO
associated with colorectal cancer; DNA:SNP:3'utr: (rs7963551) (human)
RGD
PMID:29245274
RGD:151361161
NCBI chr 4:153,106,062...153,128,598
Ensembl chr 4:153,106,062...153,128,207
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Ramp2
receptor activity modifying protein 2
ISO
RGD
PMID:31754214
RGD:152985691
NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829
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Rb1
RB transcriptional corepressor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27137931
NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
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Reck
reversion-inducing-cysteine-rich protein with kazal motifs
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17233834
NCBI chr 5:58,102,961...58,169,516
Ensembl chr 5:58,102,981...58,169,502
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Rhoa
ras homolog family member A
ISO
associated with Ovarian Neoplasms
RGD
PMID:12808121
RGD:2298873
NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
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Rhoc
ras homolog family member C
ISO
associated with Ovarian Neoplasms CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:18230616 PMID:12808121
RGD:2298873
NCBI chr 2:192,287,065...192,293,292
Ensembl chr 2:192,287,130...192,295,306
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Rit1
Ras-like without CAAX 1
ameliorates
ISO
associated with esophagus squamous cell carcinoma; human cells in mouse model
RGD
PMID:30348939
RGD:152999018
NCBI chr 2:174,180,742...174,195,455
Ensembl chr 2:174,180,848...174,195,455
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Ror1
receptor tyrosine kinase-like orphan receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28114269
NCBI chr 5:114,744,311...115,088,155
Ensembl chr 5:114,744,304...115,088,155
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Rps6ka3
ribosomal protein S6 kinase A3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21488662
NCBI chr X:35,517,306...35,623,296
Ensembl chr X:35,517,306...35,623,207
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Rxra
retinoid X receptor alpha
IEP
associated with Prostatic Neoplasms
RGD
PMID:15318950
RGD:1643115
NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
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S100a4
S100 calcium-binding protein A4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21636539 PMID:21685359 PMID:36008464
NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254
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Serpina1
serpin family A member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17085005
NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339
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Serpinb5
serpin family B member 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19514085
NCBI chr13:22,985,557...23,005,756
Ensembl chr13:22,985,557...23,005,756
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Serpinc1
serpin family C member 1
treatment
ISO
associated with Adenocarcinoma, Colon associated with Melanoma
RGD
PMID:16440418 PMID:16440418
RGD:1599327 , RGD:1599327
NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293
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Serpinf1
serpin family F member 1
IEP
associated with Prostatic Neoplasms
RGD
PMID:15313905
RGD:2312355
NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
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Sirt1
sirtuin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27793039
NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
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Six1
SIX homeobox 1
ISO
human gene in a mouse model
RGD
PMID:23435380
RGD:11561950
NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975
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Slc39a4
solute carrier family 39 member 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20957146
NCBI chr 7:108,333,368...108,337,553
Ensembl chr 7:108,333,381...108,337,553
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Slc39a6
solute carrier family 39 member 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12839489
NCBI chr18:15,864,874...15,885,417
Ensembl chr18:15,864,875...15,885,417
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Slc3a2
solute carrier family 3 member 2
ISO
RGD
PMID:19018776
RGD:151361278
NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
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Slc7a11
solute carrier family 7 member 11
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19015640
NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
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Slc7a5
solute carrier family 7 member 5
ISO
RGD
PMID:19018776
RGD:151361278
NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
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Slco1b2
solute carrier organic anion transporter family member 1B2
IEP
associated with Colonic Neoplasms;protein:decreased expression:liver
RGD
PMID:16895976
RGD:2302565
NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981
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Smad4
SMAD family member 4
disease_progression
ISO
associated with colorectal carcinoma;DNA:mutation:cds:
RGD
PMID:10340381
RGD:21066333
NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
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Smo
smoothened, frizzled class receptor
ISO
associated with colon cancer
RGD
PMID:23098507
RGD:150340555
NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829
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Snai1
snail family transcriptional repressor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22580338 PMID:23219715
NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
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Snai2
snail family transcriptional repressor 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22580338
NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200
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Sncg
synuclein, gamma
ISO
protein:increased expression:breast DNA:hypomethylation: :
RGD
PMID:16821081 PMID:16140929
RGD:6478795 , RGD:6478797
NCBI chr16:9,700,513...9,705,751
Ensembl chr16:9,700,514...9,705,368
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Sod2
superoxide dismutase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12538496 PMID:18930813 PMID:19487542 PMID:22580338
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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Sox30
SRY-box transcription factor 30
ISO
associated with lung non-small cell carcinoma;mRNA, protein:decreased expression: :
RGD
PMID:29739711
RGD:151660333
NCBI chr10:30,417,499...30,446,441
Ensembl chr10:30,418,473...30,446,453
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Sox9
SRY-box transcription factor 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:32682831
NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
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Sp1
Sp1 transcription factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12538496 PMID:35072892
NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
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Spa17
sperm autoantigenic protein 17
ISO
associated with ovarian carcinoma;proetin:increased expression:epithelium:
RGD
PMID:19744347
RGD:27226802
NCBI chr 8:37,307,432...37,318,519
Ensembl chr 8:37,307,557...37,318,639
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Spp1
secreted phosphoprotein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:22407340 PMID:16474180
RGD:1581330
NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
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Src
SRC proto-oncogene, non-receptor tyrosine kinase
ISO
associated with colorectal carcinoma;protein:increased activity:colorectum:
RGD
PMID:15486073 PMID:7687314
RGD:1581401 , RGD:150521537
NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
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Srebf2
sterol regulatory element binding transcription factor 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30394316
NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
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Srsf1
serine and arginine rich splicing factor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17085005
NCBI chr10:72,838,926...72,859,066
Ensembl chr10:72,839,274...72,845,336
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Srsf2
serine and arginine rich splicing factor 2
severity
ISO
associated with hepatocellular carcinoma
RGD
PMID:29278882
RGD:150429692
NCBI chr10:102,052,158...102,055,365
Ensembl chr10:102,052,314...102,055,338
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Srsf5
serine and arginine rich splicing factor 5
ISO
associated with Ovarian Neoplasms;mRNA:increased expression:epithelium of female gonad (human)
RGD
PMID:23748175
RGD:11039469
NCBI chr 6:100,605,165...100,610,192
Ensembl chr 6:100,605,456...100,610,177
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Srsf6
serine and arginine rich splicing factor 6
ISO
associated with Ovarian Neoplasms;mRNA:increased expression:epithelium of female gonad (human)
RGD
PMID:23748175
RGD:11039469
NCBI chr 3:151,589,546...151,594,869
Ensembl chr 3:151,589,535...151,594,860
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St14
ST14 transmembrane serine protease matriptase
ISO
associated with Prostatic Neoplasms associated with Breast Neoplasms
RGD
PMID:18813126 PMID:17456594
RGD:2315088 , RGD:2315092
NCBI chr 8:29,540,805...29,581,704
Ensembl chr 8:29,540,811...29,581,517
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Stat1
signal transducer and activator of transcription 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:29147627
NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
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Stat3
signal transducer and activator of transcription 3
treatment
ISO
associated with Carcinoma, Renal Cell;protein:increased phosphorylation CTD Direct Evidence: marker/mechanism associated with Melanoma associated with Prostatic Neoplasms;protein:decreased activity
CTD RGD
PMID:21937440 PMID:23382965 PMID:26101800 PMID:12131365 PMID:16540670 PMID:17382154 More...
RGD:2291917 , RGD:8694303 , RGD:2291915
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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Stat5a
signal transducer and activator of transcription 5A
disease_progression
ISO
DNA:CNV: :prostate (human)
RGD
PMID:23660011
RGD:151667415
NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
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Stim1
stromal interaction molecule 1
ameliorates treatment exacerbates
ISO
human cells in mouse model;associated with lung cancer associated with stomach cancer; human cells in mouse model associated with hepatocellular carcinoma;protein:decreased expression:liver (human) associated with nasopharynx carcinoma; human cells in mouse model
RGD
PMID:28713917 PMID:27431311 PMID:32483465 PMID:32165272
RGD:152995357 , RGD:152995400 , RGD:152995387 , RGD:152995361
NCBI chr 1:156,656,246...156,818,777
Ensembl chr 1:156,656,013...156,818,363
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Sult1e1
sulfotransferase family 1E member 1
IEP
associated with Colonic Neoplasms;protein:increased expression:liver
RGD
PMID:16895976
RGD:2302565
NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275
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Tbcb
tubulin folding cofactor B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17085005
NCBI chr 1:85,477,639...85,483,488
Ensembl chr 1:85,477,640...85,483,488
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Tcf3
transcription factor 3
disease_progression
ISO
associated with colon cancer
RGD
PMID:26212009
RGD:11533019
NCBI chr 7:9,280,571...9,302,315
Ensembl chr 7:9,280,571...9,302,314
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Tet2
tet methylcytosine dioxygenase 2
ISO
associated with colorectal cancer; protein:decreased expression:colorectum (human)
RGD
PMID:33552282
RGD:150429609
NCBI chr 2:221,988,645...222,072,813
Ensembl chr 2:221,988,645...222,072,534
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Tfpi2
tissue factor pathway inhibitor 2
disease_progression
ISO
CTD Direct Evidence: marker/mechanism associated with stomach carcinoma;DNA:hypermethylation
CTD RGD
PMID:17372906 PMID:25009298
RGD:150527841
NCBI chr 4:31,981,786...31,986,707
Ensembl chr 4:31,982,178...31,986,600
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Tgfb1
transforming growth factor, beta 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23146760 PMID:23992306 PMID:26896736 PMID:31381904
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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Tgfbr1
transforming growth factor, beta receptor 1
ISO
associated with Mammary Neoplasms, Experimental
RGD
PMID:12808151
RGD:737735
NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
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Tgfbr2
transforming growth factor, beta receptor 2
ISO
associated with Mammary Neoplasms, Experimental CTD Direct Evidence: therapeutic
CTD RGD
PMID:16489006 PMID:12808151
RGD:737735
NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
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Tgif1
TGFB-induced factor homeobox 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:29746904
NCBI chr 9:110,748,094...110,757,714
Ensembl chr 9:110,720,921...110,757,802
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Timp1
TIMP metallopeptidase inhibitor 1
ISO
associated with Breast Neoplasms;protein:increased expression:plasma
RGD
PMID:17407159
RGD:2290346
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
G
Timp2
TIMP metallopeptidase inhibitor 2
ISO
associated with Breast Neoplasms
RGD
PMID:17505812
RGD:2290394
NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
G
Tlr4
toll-like receptor 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22180778
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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Tnc
tenascin C
ISO
associated with Carcinoma, Renal Cell;protein:increased expression:lung
RGD
PMID:16928692
RGD:4889612
NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
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Tnf
tumor necrosis factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:8032535 PMID:23431386
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tnfaip8
TNF alpha induced protein 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21969086
NCBI chr18:43,183,854...43,299,512
Ensembl chr18:43,183,916...43,299,517
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Tnfrsf11a
TNF receptor superfamily member 11A
ISO
associated with Prostatic Neoplasms;protein:increased expression:bone, lymph node
RGD
PMID:16752412
RGD:2302322
NCBI chr13:21,928,370...21,986,719
Ensembl chr13:21,928,408...21,986,695
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Tnfrsf11b
TNF receptor superfamily member 11B
ISO
associated with Breast Neoplasms;protein:increased expression:serum
RGD
PMID:23167338
RGD:7205479
NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
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Tnfsf10
TNF superfamily member 10
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:21209944
NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
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Tp53
tumor protein p53
ISO IMP
CTD Direct Evidence: marker/mechanism associated with Sarcoma;
CTD RGD
PMID:17949449 PMID:22009531 PMID:23873029 PMID:27137931 PMID:15118671 PMID:21854749 More...
RGD:1331525 , RGD:11075090
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Tp63
tumor protein p63
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15875781
NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
G
Tpm4
tropomyosin 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17085005
NCBI chr16:17,684,415...17,698,456
Ensembl chr16:17,683,195...17,705,984
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Ttr
transthyretin
treatment
ISO
associated with colorectal adenocarcinoma;protein:decreased expression:colorectum (human) associated with colorectal cancer associated with oral squamous cell carcinoma;protein:decreased expression:blood serum, saliva (human)
RGD
PMID:33739034 PMID:28730771 PMID:20957082
RGD:151660505 , RGD:151665163 , RGD:151665158
NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
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Twist1
twist family bHLH transcription factor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19806464
NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653
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Txn1
thioredoxin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30396169
NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
G
Txndc5
thioredoxin domain containing 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17085005
NCBI chr17:26,289,880...26,318,025
Ensembl chr17:26,289,880...26,318,025
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Tymp
thymidine phosphorylase
ISO
associated with Breast Neoplasms CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:11103787 PMID:18441329
RGD:2293714
NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874 Ensembl chr 7:120,438,770...120,443,874
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Tyms
thymidylate synthetase
disease_progression
ISO
associated with Gastrointestinal Neoplasms;DNA:SNPs: :
RGD
PMID:25677447
RGD:11081002
NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
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Tyr
tyrosinase
no_association
ISO
associated with melanoma;
RGD
PMID:11092039
RGD:8694395
NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207
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Uchl3
ubiquitin C-terminal hydrolase L3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17085005
NCBI chr15:78,485,304...78,527,355
Ensembl chr15:78,485,315...78,527,355 Ensembl chr 3:78,485,315...78,527,355
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Vcam1
vascular cell adhesion molecule 1
ISO
associated with Pancreatic Neoplasms;protein:increased expression:serum
RGD
PMID:12923961
RGD:2325163
NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
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Vdr
vitamin D receptor
ISO
associated with breast cancer;DNA:SNP:intron: (rs1544410) (human)
RGD
PMID:9613456
RGD:8158057
NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
G
Vegfa
vascular endothelial growth factor A
ISO
associated with Carcinoma, Renal Cell CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:15659795 PMID:18930813 PMID:20158913 PMID:19064974
RGD:2315468
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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Vim
vimentin
treatment
ISO
CTD Direct Evidence: marker/mechanism associated with stomach cancer; human cells in mouse model
CTD RGD
PMID:17085005 PMID:27431311
RGD:152995400
NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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Vip
vasoactive intestinal peptide
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19189304
NCBI chr 1:42,064,878...42,073,219
Ensembl chr 1:42,065,120...42,073,216
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Wfdc18
WAP four-disulfide core domain 18
IEP
associated with Mammary Neoplasms, Experimental;mRNA:increased expression
RGD
PMID:3136918
RGD:632771
NCBI chr10:68,588,818...68,590,972
Ensembl chr10:68,588,818...68,589,671
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Xpc
XPC complex subunit, DNA damage recognition and repair factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27777383
NCBI chr 4:123,993,670...124,020,922
Ensembl chr 4:123,993,666...124,021,010
G
Xrcc1
X-ray repair cross complementing 1
susceptibility
ISO
associated with Neoplasms, Germ Cell and Embryonal;DNA:polymorphism: :p.R399Q
RGD
PMID:16596238
RGD:2302576
NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701
G
Yap1
Yes1 associated transcriptional regulator
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28114269
NCBI chr 8:5,095,705...5,166,808
Ensembl chr 8:5,095,722...5,167,010
G
Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17085005
NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589
G
Zfhx3
zinc finger homeobox 3
exacerbates
ISO
brain metastasis associated with lung adenocarcinoma;DNA:mutations:multiple (human)
RGD
PMID:33479213
RGD:151361170
NCBI chr19:36,257,196...36,886,104
Ensembl chr19:36,630,254...36,881,771
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Zfp382
zinc finger protein 382
disease_progression
ISO
associated with stomach carcinoma;DNA:hypermethylation
RGD
PMID:25009298
RGD:150527841
NCBI chr 1:85,377,614...85,400,832
Ensembl chr 1:85,377,484...85,399,667
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Alox12
arachidonate 12-lipoxygenase, 12S type
ISO
associated with Prostatic Neoplasms;
RGD
PMID:14669797
RGD:1578303
NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542
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Brip1
BRCA1 interacting helicase 1
ISO
associated with Breast Neoplasms; human gene in a mouse model
RGD
PMID:22875853
RGD:11252149
NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324
G
Cxcr4
C-X-C motif chemokine receptor 4
disease_progression
ISO
associated with hepatocellular carcinoma;protein:increased expression:liver (human)
RGD
PMID:19508713
RGD:152023653
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
G
Enpp1
ectonucleotide pyrophosphatase/phosphodiesterase 1
ISO
associated with Breast Neoplasms;mRNA:increased expression:bone element (human)
RGD
PMID:23861746
RGD:13204736
NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715
G
Mir34a
microRNA 34a
susceptibility
ISO
associated with hepatocellular carcinoma;miRNA:decreased expression:serum, bone
RGD
PMID:27893432
RGD:14694837
NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103
G
Mmp13
matrix metallopeptidase 13
ISO
associated with Carcinoma, Renal Cell; mRNA, protein:increased expression:bone (human)
RGD
PMID:18709334
RGD:2306080
NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
G
Pdgfd
platelet derived growth factor D
ISO
associated with prostate carcinoma
RGD
PMID:22158043
RGD:13506772
NCBI chr 8:3,488,448...3,722,395
Ensembl chr 8:3,488,423...3,722,395
G
Erbb2
erb-b2 receptor tyrosine kinase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:29044505
NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
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Ace
angiotensin I converting enzyme
ISO
associated with colorectal cancer;mRNA:increased expression:liver (mouse)
RGD
PMID:20380732
RGD:25671446
NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
G
Braf
B-Raf proto-oncogene, serine/threonine kinase
severity
IAGP
associated with colorectal cancer;DNA:mutation:cds: associated with colorectal cancer;DNA:mutations:multiple associated with skin melanoma;DNA:missense mutations:cds: associated with colorectal cancer;DNA:missense mutations:cds:pV599E,p.V600E (human) associated with colorectal cancer;DNA:missense mutation:cds:p.V600E (human)
RGD
PMID:27737491 PMID:26775732 PMID:28787433 PMID:22331825 PMID:23010994
RGD:18337264 , RGD:11554843 , RGD:14696791 , RGD:18337265 , RGD:15039394
NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
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Ccl2
C-C motif chemokine ligand 2
disease_progression
ISO
associated with colorectal cancer
RGD
PMID:27058904
RGD:14995463
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Ccl5
C-C motif chemokine ligand 5
treatment
ISO
associated with Animal Mammary Neoplasms;
RGD
PMID:15692764
RGD:14995455
NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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Ccnd2
cyclin D2
ISO
associated with colorectal cancer;protein:increased expression:colorectum
RGD
PMID:19508551
RGD:151665111
NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
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Ccng1
cyclin G1
treatment
ISO
human cells in mouse model
RGD
PMID:10910035
RGD:151356987
NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
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Cd44
CD44 molecule
ISO
associated with Breast Neoplasm;protein:increased expression:liver
RGD
PMID:17991717
RGD:2289349
NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
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Chd4
chromodomain helicase DNA binding protein 4
ameliorates
ISO
associated with human colon adenocarcinoma cells in a mouse model
RGD
PMID:28486105
RGD:153323299
NCBI chr 4:157,898,503...157,931,632
Ensembl chr 4:157,899,391...157,931,541
G
Cxcl10
C-X-C motif chemokine ligand 10
treatment
ISO
associated with colon carcinoma;
RGD
PMID:30381616
RGD:27095891
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
G
Cxcl12
C-X-C motif chemokine ligand 12
ameliorates
ISO
associated with colorectal cancer; human cells in mouse model
RGD
PMID:30789971
RGD:151893289
NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
G
Cxcr4
C-X-C motif chemokine receptor 4
ameliorates
ISO
associated with colorectal cancer; human cells in mouse model human cells in mouse model; associated with colorectal cancer
RGD
PMID:30789971 PMID:29436696
RGD:151893289 , RGD:152023643
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
G
Daxx
death-domain associated protein
exacerbates
ISO
associated with colon cancer; mRNA:decreased expression:liver (human) associated with pancreatic endocrine carcinoma;DNA:mutations:CDS:multiple (human) associated with neuroendocrine tumor;DNA:mutations:CDS:multiple (human)
RGD
PMID:31942198 PMID:30339629 PMID:30342802
RGD:152025194 , RGD:152025203 , RGD:152025199
NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
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Ddr1
discoidin domain receptor tyrosine kinase 1
treatment
ISO
mRNA:increased expression:liver (mouse) human cells in mouse model; nilotinib
RGD
PMID:33110221 PMID:30666650 PMID:29438985
RGD:151347537 , RGD:151347840 , RGD:151347685
NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468
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Ddr2
discoidin domain receptor tyrosine kinase 2
ameliorates
ISO
associated with colon carcinoma associated with melanoma;
RGD
PMID:22071959 PMID:21701781
RGD:150429701 , RGD:150429713
NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363
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Dock6
dedicator of cytokinesis 6
ameliorates
ISO
associated with stomach cancer;
RGD
PMID:29587866
RGD:155791564
NCBI chr 8:20,342,430...20,394,660
Ensembl chr 8:20,342,089...20,394,552
G
Fbxw7
F-box and WD repeat domain containing 7
disease_progression
ISO
associated with colorectal cancer;
RGD
PMID:28846828
RGD:21408566
NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941
G
Fgfr1
Fibroblast growth factor receptor 1
ISO
associated with colorectal cancer;mRNA:increased expression:colorectal mucosa:
RGD
PMID:19082464
RGD:25330357
NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350
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Fosl2
FOS like 2, AP-1 transcription factor subunit
ISO
human cells in mouse model
RGD
PMID:30114390
RGD:153344554
NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034
G
Gpc3
glypican 3
ISO
protein:increased expression:blood serum (human)
RGD
PMID:28801286
RGD:243065135
NCBI chr X:131,868,986...132,236,824
Ensembl chr X:131,868,990...132,236,798
G
Hmbs
hydroxymethylbilane synthase
IEP
associated with colon adenocarcinoma;protein:decreased activity:liver(rat)
RGD
PMID:1386052
RGD:25440496
NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957
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Il2
interleukin 2
treatment
ISO
associated with Colorectal Neoplasms, Carcinoma, Hepatocellular; associated with colon carcinoma
RGD
PMID:11591892 PMID:9354462
RGD:8663446 , RGD:14928215
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
G
Iqsec1
IQ motif and Sec7 domain ArfGEF 1
ISO
human cells in mouse model
RGD
PMID:22662237
RGD:153344589
NCBI chr 4:123,168,719...123,488,300
Ensembl chr 4:123,168,719...123,488,172
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Map2k7
mitogen activated protein kinase kinase 7
ISO
associated with colon cancer;protein:increased expression:colon (human)
RGD
PMID:24533778
RGD:155259116
NCBI chr12:2,591,312...2,600,534
Ensembl chr12:2,591,219...2,604,222
G
Mir141
microRNA 141
ISO
associated with colorectal cancer;RNA:increased expression:liver:
RGD
PMID:28617555
RGD:14928321
NCBI chr 4:157,523,239...157,523,332
Ensembl chr 4:157,523,239...157,523,332
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Mir148b
microRNA 148b
exacerbates
ISO
associated with stomach cancer;
RGD
PMID:29587866
RGD:155791564
NCBI chr 7:134,421,398...134,421,494
Ensembl chr 7:134,421,398...134,421,494
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Mir155
microRNA 155
ISO
RGD
PMID:26885061
RGD:21079444
NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
G
Mir200b
microRNA 200b
ISO
associated with colorectal cancer;RNA:increased expression:liver:
RGD
PMID:28617555
RGD:14928321
NCBI chr 5:166,649,272...166,649,366
Ensembl chr 5:166,649,272...166,649,366
G
Mir200c
microRNA 200c
ISO
associated with colorectal cancer;RNA:increased expression:liver:
RGD
PMID:28617555
RGD:14928321
NCBI chr 4:157,523,679...157,523,747
G
Mir223
microRNA 223
disease_progression
ISO
associated with colorectal cancer;
RGD
PMID:28846828
RGD:21408566
NCBI chr X:61,141,887...61,141,996
Ensembl chr X:61,141,887...61,141,996
G
Mir494
microRNA 494
exacerbates
ISO
associated with pancreatic ductal adenocarcinoma;
RGD
PMID:24859161
RGD:156430321
NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793
G
Mpl
MPL proto-oncogene, thrombopoietin receptor
severity exacerbates
ISO
associated with pancreatic ductal adenocarcinoma; human cells in mouse model associated with colorectal carcinoma;protein:increased expression:colorectum (human) associated with pancreatic cancer; protein:increased expression:liver, pancreas (human)
RGD
PMID:30770989 PMID:23747337 PMID:30770989
RGD:126925751 , RGD:126925752 , RGD:126925751
NCBI chr 5:131,973,895...131,987,472
Ensembl chr 5:131,973,895...131,986,797
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Nras
NRAS proto-oncogene, GTPase
susceptibility
ISO
human gene in a mouse model;DNA:missense mutations:cds:p.G12V, p.Q61K (human) associated with colorectal cancer;DNA:mutations:exons (human) associated with melanoma;DNA:mutations: exons (human)
RGD
PMID:26799184 PMID:28011498 PMID:28787433
RGD:14696774 , RGD:14696792 , RGD:14696791
NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626
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Ptprb
protein tyrosine phosphatase, receptor type, B
treatment
ISO
mouse tumor cells in mouse recipient
RGD
PMID:31348125
RGD:151660353
NCBI chr 7:51,953,375...52,034,751
Ensembl chr 7:51,930,015...52,034,748
G
Rictor
RPTOR independent companion of MTOR, complex 2
disease_progression
ISO
mRNA:increased expression:liver (human)
RGD
PMID:30404068 PMID:30404068
RGD:152995463 , RGD:152995463
NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426
G
Rnf43
ring finger protein 43
ISO
associated with colorectal adenocarcinoma;mRNA:increased expression:liver (human)
RGD
PMID:28789449
RGD:151361221
NCBI chr10:72,461,508...72,537,301
Ensembl chr10:72,464,348...72,536,977
G
Slc3a2
solute carrier family 3 member 2
severity
IEP
associated with colon adenocarcinoma
RGD
PMID:11745822
RGD:151361130
NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
G
Slc7a5
solute carrier family 7 member 5
severity
IEP
associated with colon cancer associated with colon adenocarcinoma
RGD
PMID:11718450 PMID:11745822
RGD:151361129 , RGD:151361130
NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
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Smad4
SMAD family member 4
treatment
ISO
associated with colorectal carcinoma; DNA:mutations: : associated with colorectal carcinoma;protein:decreased expression:colorectum:
RGD
PMID:29551247 PMID:17390050
RGD:18937000 , RGD:21066338
NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
G
Sox30
SRY-box transcription factor 30
ameliorates
ISO
RGD
PMID:29739711
RGD:151660333
NCBI chr10:30,417,499...30,446,441
Ensembl chr10:30,418,473...30,446,453
G
Src
SRC proto-oncogene, non-receptor tyrosine kinase
disease_progression
ISO
associated with colon cancer;protein:increased activity:colon
RGD
PMID:7678609
RGD:150521542
NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
G
Vegfa
vascular endothelial growth factor A
ISO
associated with colorectal carcinoma;mRNA,protein:increased expression:liver:
RGD
PMID:22156924
RGD:15014782
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
G
Adam28
ADAM metallopeptidase domain 28
ameliorates
ISO
associated with lung carcinoma, breast carcinoma associated with lung adenocarcinoma;
RGD
PMID:22636800 PMID:26800504
RGD:153297785 , RGD:11531771
NCBI chr15:43,774,463...43,840,726
Ensembl chr15:42,944,467...43,840,672
G
Arhgap5
Rho GTPase activating protein 5
ISO
associated with Mammary Neoplasms, Experimental
RGD
PMID:20860838
RGD:126848767
NCBI chr 6:69,975,904...70,039,299
Ensembl chr 6:69,976,214...70,037,660
G
Arid2
AT-rich interaction domain 2
exacerbates
ISO
associated with hepatocellular carcinoma,
RGD
PMID:32071245
RGD:150340708
NCBI chr 7:127,447,192...127,565,987
Ensembl chr 7:127,447,278...127,563,512
G
Azgp1
alpha-2-glycoprotein 1, zinc-binding
ameliorates
ISO
associated with hepatocellular carcinoma;
RGD
PMID:27993894 PMID:26902423
RGD:153350132 , RGD:153350133
NCBI chr12:16,930,990...16,939,333
Ensembl chr12:16,931,024...16,939,091
G
Car12
carbonic anhydrase 12
ameliorates
ISO
associated with breast cancer;
RGD
PMID:29786141
RGD:155226861
NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440
G
Cblb
Cbl proto-oncogene B
severity
ISO
associated with stomach carcinoma;
RGD
PMID:28334634
RGD:150540337
NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839
G
Ccng1
cyclin G1
ISO
RGD
PMID:30565428
RGD:151361205
NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
G
Chd4
chromodomain helicase DNA binding protein 4
ameliorates
ISO
associated with human colon adenocarcinoma cells in a mouse model
RGD
PMID:28486105
RGD:153323299
NCBI chr 4:157,898,503...157,931,632
Ensembl chr 4:157,899,391...157,931,541
G
Col10a1
collagen type X alpha 1 chain
ameliorates
ISO
associated with H1299 cell
RGD
PMID:33324550
RGD:150429752
NCBI chr20:38,183,103...38,189,488
Ensembl chr20:38,182,494...38,189,494
G
Cxcr4
C-X-C motif chemokine receptor 4
ameliorates
ISO
associated with colorectal cancer; human cells in mouse model associated with nasopharynx carcinoma; human cells in mouse model associated with osteosarcoma and melanoma
RGD
PMID:31938138 PMID:16000558 PMID:26498029 PMID:18071913
RGD:151665329 , RGD:151893515 , RGD:152023752 , RGD:152177473
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
G
Ddr1
discoidin domain receptor tyrosine kinase 1
ISO
RGD
PMID:29483153
RGD:151347599
NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468
G
Ddr2
discoidin domain receptor tyrosine kinase 2
exacerbates
ISO
associated with tongue squamous cell carcinoma;
RGD
PMID:24556606
RGD:150429746
NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363
G
Fasn
fatty acid synthase
ISO
associated with head and neck squamous cell carcinoma
RGD
PMID:20604875
RGD:126790467
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
G
Fosl2
FOS like 2, AP-1 transcription factor subunit
ISO
human cells in mouse model
RGD
PMID:30326930
RGD:153344557
NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034
G
Hilpda
hypoxia inducible lipid droplet-associated
ISO
human cells in mouse model
RGD
PMID:31142329
RGD:153344574
NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:57,871,110...57,874,557
G
Iqsec1
IQ motif and Sec7 domain ArfGEF 1
ISO
human cells in mouse model
RGD
PMID:18084281
RGD:153344604
NCBI chr 4:123,168,719...123,488,300
Ensembl chr 4:123,168,719...123,488,172
G
Itgav
integrin subunit alpha V
treatment
ISO
human cells in rat model
RGD
PMID:20841470
RGD:152998949
NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639
G
Map3k1
mitogen-activated protein kinase kinase kinase 1
ameliorates
ISO
associated with breast carcinoma
RGD
PMID:16568086
RGD:150573808
NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463
G
Map3k8
mitogen-activated protein kinase kinase kinase 8
ameliorates
ISO
associated with clear cell renal cell carcinoma
RGD
PMID:23982215
RGD:151356974
NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216
G
Mir423
microRNA 423
ISO
human cells in mouse model
RGD
PMID:30326930
RGD:153344557
NCBI chr10:61,914,142...61,914,220
Ensembl chr10:61,914,133...61,914,226
G
Mir494
microRNA 494
ameliorates
ISO
associated with hepatocellular carcinoma
RGD
PMID:25820676 PMID:28055013
RGD:155900754 , RGD:156430322
NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793
G
Nf2
NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor
ISO
associated with hepatocellular carcinoma
RGD
PMID:26443326
RGD:11076529
NCBI chr14:79,627,399...79,710,709
Ensembl chr14:79,627,399...79,710,667
G
Ntrk3
neurotrophic receptor tyrosine kinase 3
ameliorates
ISO
associated with mammary carcinoma
RGD
PMID:20802235
RGD:150520014
NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286
G
Pagr1
Paxip1-associated glutamate-rich protein 1
ISO
human cells in mouse model
RGD
PMID:33833989
RGD:153344568
NCBI chr 1:181,622,698...181,625,024
G
Ptprb
protein tyrosine phosphatase, receptor type, B
treatment
ISO
RGD
PMID:23899555
RGD:151660352
NCBI chr 7:51,953,375...52,034,751
Ensembl chr 7:51,930,015...52,034,748
G
Rictor
RPTOR independent companion of MTOR, complex 2
ISO
human cells in mouse model
RGD
PMID:20978191 PMID:29809146
RGD:152995469 , RGD:152995516
NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426
G
Rptor
regulatory associated protein of MTOR, complex 1
ISO
RGD
PMID:29809146
RGD:152995516
NCBI chr10:104,878,487...105,176,986
Ensembl chr10:104,878,487...105,176,983
G
Sf3b4
splicing factor 3B subunit 4
ISO
human cells in mouse model
RGD
PMID:30391496
RGD:155804298
NCBI chr 2:183,732,791...183,737,545
Ensembl chr 2:183,732,754...183,737,959
G
Sox30
SRY-box transcription factor 30
ameliorates
ISO
RGD
PMID:29739711
RGD:151660333
NCBI chr10:30,417,499...30,446,441
Ensembl chr10:30,418,473...30,446,453
G
Src
SRC proto-oncogene, non-receptor tyrosine kinase
treatment ameliorates
ISO
associated with breast cancer; associated with nasopharynx carcinoma;
RGD
PMID:15753384 PMID:27078847
RGD:1581400 , RGD:150521726
NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
G
Abca13
ATP binding cassette subfamily A member 13
susceptibility
ISO
DNA:amplification:cds: (human, male)
RGD
PMID:27366209
RGD:152995256
NCBI chr14:83,873,397...84,376,138
Ensembl chr14:83,873,940...84,375,075
G
Adam28
ADAM metallopeptidase domain 28
ISO
associated with breast cancer;DNA:hypermethylation:
RGD
PMID:25620615
RGD:153298970
NCBI chr15:43,774,463...43,840,726
Ensembl chr15:42,944,467...43,840,672
G
Adgrb1
adhesion G protein-coupled receptor B1
disease_progression
ISO
associated with stomach cancer;
RGD
PMID:11172604
RGD:13831357
NCBI chr 7:106,404,827...106,476,902
Ensembl chr 7:106,404,958...106,476,902
G
Aicda
activation-induced cytidine deaminase
ISO
associated with stomach cancer;protein:increased expression:stomach (human)
RGD
PMID:21538122
RGD:127285638
NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972
G
Angptl4
angiopoietin-like 4
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:17130448
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
G
Anxa1
annexin A1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19381893
NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
G
Aqp3
aquaporin 3 (Gill blood group)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21401805
NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
G
Arhgap5
Rho GTPase activating protein 5
ISO
associated with nasopharynx carcinoma;mRNA, protein:increased expression: epithelium of nasopharynx
RGD
PMID:25961434
RGD:11056278
NCBI chr 6:69,975,904...70,039,299
Ensembl chr 6:69,976,214...70,037,660
G
Asxl1
ASXL transcriptional regulator 1
ISO
associated with colorectal cancer
RGD
PMID:32317519
RGD:126779580
NCBI chr 3:141,814,012...141,881,526
Ensembl chr 3:141,813,433...141,881,538
G
Axl
Axl receptor tyrosine kinase
ISO
associated Pancreatic Neoplasms
RGD
PMID:19252414
RGD:2325833
NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265
G
Bag1
BAG cochaperone 1
disease_progression
ISO
associated with Breast Neoplasms:protein:increased expression:breast
RGD
PMID:18430249
RGD:2292908
NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
G
Bambi
BMP and activin membrane-bound inhibitor
ISO
associated with stomach cancer; protein:increased expression: :
RGD
PMID:24752577
RGD:14390158
NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060
G
Barhl2
BarH-like homeobox 2
ISO
associated with oral squamous cell carcinoma; mRNA:decreased expression:mouth mucosa
RGD
PMID:27542258
RGD:14390167
NCBI chr14:3,340,465...3,345,362
Ensembl chr14:3,340,465...3,345,353
G
Bcl2
BCL2, apoptosis regulator
ISO
associated with Breast Neoplasms;protein:increased expression:lymph node
RGD
PMID:18217456
RGD:2293013
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
G
Bik
BCL2-interacting killer
ISO
associated with cholangiocarcinoma;DNA:CNV::
RGD
PMID:16865775
RGD:14394820
NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296
G
Birc5
baculoviral IAP repeat-containing 5
disease_progression
ISO
associated with Cervix Neoplasms;mRNA:splice variant associated with Breast Neoplasms
RGD
PMID:17877643 PMID:17285241
RGD:2293098 , RGD:2293103
NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
G
Braf
B-Raf proto-oncogene, serine/threonine kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:29426936
NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
G
Brd7
bromodomain containing 7
severity
ISO
protein:increased expression:lung:
RGD
PMID:22008115
RGD:9586442
NCBI chr19:18,708,792...18,737,497
Ensembl chr19:18,709,022...18,737,494
G
Bsg
basigin
disease_progression
ISO
associated with Breast Neoplasms
RGD
PMID:16004819
RGD:2289055
NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387
G
Btk
Bruton tyrosine kinase
disease_progression
ISO
associated with lung adenocarcinoma;protein:increased expression:lung (human)
RGD
PMID:31200752
RGD:151347847
NCBI chr X:97,722,796...97,762,315
Ensembl chr X:97,722,802...97,761,853
G
Cab39
calcium binding protein 39
ISO
associated with pancreatic cancer;RNA:increased expression:pancreas
RGD
PMID:28197410
RGD:14398834
NCBI chr 9:86,463,095...86,524,545
Ensembl chr 9:86,463,095...86,524,544
G
Car9
carbonic anhydrase 9
ISO
associated with Cervix Neoplasms
RGD
PMID:17233814
RGD:2293196
NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
G
Casp9
caspase 9
ISO
associated with Carcinoma, Non-Small-Cell Lung;DNA:SNP:exon:rs1052576 (human)
RGD
PMID:17285546
RGD:13434907
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
G
Cav1
caveolin 1
disease_progression
ISO
associated with Melanoma
RGD
PMID:22134245
RGD:8661767
NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
G
Cbl
Cbl proto-oncogene
ISO
associated with stomach carcinoma;protein:increased expression:stomach
RGD
PMID:31611438
RGD:126925223
NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176
G
Cblb
Cbl proto-oncogene B
ISO
associated with stomach carcinoma;
RGD
PMID:20038312
RGD:150540338
NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839
G
Ccnd2
cyclin D2
ISO
associated with colorectal cancer;protein:increased expression:colorectum
RGD
PMID:19508551
RGD:151665111
NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
G
Ccne1
cyclin E1
ISO
associated with Carcinoma, Transitional Cell;protein:decreased expression
RGD
PMID:16949911
RGD:2289266
NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
G
Ccnh
cyclin H
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30705370
NCBI chr 2:15,835,064...15,855,648
Ensembl chr 2:15,834,833...15,855,819
G
Ccr5
C-C motif chemokine receptor 5
ISO
associated with Breast Neoplasms;mRNA:increased expression:lymph node
RGD
PMID:24301790
RGD:8551816
NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
G
Cd274
CD274 molecule
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16530813
NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450
G
Cd40
CD40 molecule
ISO
associated with breast cancer;DNA:snps:5' utr, intron:c.-1T>C, c.51+914T>G (rs1883832, rs4810485) (human)
RGD
PMID:21912605
RGD:8547780
NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
G
Cd44
CD44 molecule
ISO
associated with Breast Neoplasms, Colorectal Neoplasms, Stomach Neoplasms;mRNA, protein:splice variant, increased expression:breast, large intestine, stomach
RGD
PMID:16425351
RGD:2289356
NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
G
Cdh1
cadherin 1
ISO
associated with Cervix Neoplasms associated with Breast Neoplasms
RGD
PMID:18097581 PMID:17649807
RGD:2296046 , RGD:2289498
NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
ISO
associated with Eyelid Neoplasms; associated with Oral Squamous Cell Carcinoma;
RGD
PMID:19628749 PMID:15817070
RGD:8661799 , RGD:8662374
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
G
Cdkn1b
cyclin-dependent kinase inhibitor 1B
ISO
associated with Breast Neoplasms associated with non-small cell lung carcinoma
RGD
PMID:12015771 PMID:28601655
RGD:2293607 , RGD:13673921
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
G
Cdkn2a
cyclin-dependent kinase inhibitor 2A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:29426936
NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
G
Cldn1
claudin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:33665778
NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
G
Clptm1l
CLPTM1-like
ISO
associated with esophagus squamous cell carcinoma; mRNA:increased expression:esophagus
RGD
PMID:25480402
RGD:150530497
NCBI chr 1:29,667,545...29,683,530
Ensembl chr 1:29,667,545...29,683,530
G
Clu
clusterin
ISO
associated with breast cancer;DNA:snp:promoter:g.27611345C>G (rs9331888) (human)
RGD
PMID:22037783
RGD:8963167
NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
G
Comt
catechol-O-methyltransferase
ISO
associated with breast cancer;DNA:missense mutation:cds:p.V108/158M (human)
RGD
PMID:10755383
RGD:8662330
NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
G
Crp
C-reactive protein
susceptibility
ISO
associated with Breast Neoplasm; DNA:polymorphism: :1846C>T(rs1205)(human)
RGD
PMID:24633920
RGD:9580226
NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
G
Csf1r
colony stimulating factor 1 receptor
ISO
associated with Breast Neoplasms
RGD
PMID:14734466
RGD:2293711
NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
G
Ctla4
cytotoxic T-lymphocyte-associated protein 4
ISO
associated with Prostatic Neoplasms
RGD
PMID:10611340
RGD:4891523
NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963
G
Ctnna1
catenin alpha 1
ISO
associated with Breast Neoplasms
RGD
PMID:12047765
RGD:2289795
NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910
G
Ctnnb1
catenin beta 1
ISO
associated with Breast Neoplasms;protein:decreased expression
RGD
PMID:17908479
RGD:2289813
NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
G
Cxcl12
C-X-C motif chemokine ligand 12
disease_progression
ISO
associated with stomach cancer;mRNA:increased expression:stomach (human)
RGD
PMID:21633638
RGD:152023624
NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
G
Cxcr4
C-X-C motif chemokine receptor 4
ISO
associated with nasopharynx carcinoma; protein:increased expression:lymph node (human)
RGD
PMID:16000558
RGD:151893515
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
G
Cycs
cytochrome c, somatic
ISO
associated with non-small cell lung carcinoma; protein:decreased expression:serum
RGD
PMID:25578497
RGD:13792769
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
G
Ddr1
discoidin domain receptor tyrosine kinase 1
severity
ISO
mRNA, protein:increased expression:mouth (human) mRNA:increased expression:kidney, lymph nodes (human)
RGD
PMID:31253192 PMID:27020590
RGD:151347620 , RGD:151347863
NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468
G
Ddr2
discoidin domain receptor tyrosine kinase 2
disease_progression
ISO
associated with oral squamous cell carcinoma
RGD
PMID:29945346
RGD:150429700
NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363
G
Dnmt3b
DNA methyltransferase 3 beta
ISO
associated with Carcinoma, Pancreatic Ductal;
RGD
PMID:22919364
RGD:9589121
NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124
G
Ebag9
estrogen receptor binding site associated antigen 9
ISO
associated with Prostatic Neoplasm;protein:increased expression:prostate gland, lymph node associated with Breast Neoplasms;protein:increased expression:breast
RGD
PMID:12845666 PMID:12054692 PMID:17187007
RGD:2289856 , RGD:2298489 , RGD:2289847
NCBI chr 7:75,810,950...75,828,902
Ensembl chr 7:75,810,594...75,861,248
G
Egfr
epidermal growth factor receptor
treatment
ISO
associated with Squamous Cell Carcinoma of the Tongue
RGD
PMID:19380367
RGD:8551769
NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
G
Ehmt2
euchromatic histone lysine methyltransferase 2
ISO
associated with Melanoma; associated with Esophageal Squamous Cell Carcinoma;
RGD
PMID:24658378 PMID:24805087
RGD:9590069 , RGD:9590071
NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547
G
Epha2
Eph receptor A2
ISO
protein:increased expression:esophagus (human)
RGD
PMID:33833989
RGD:153344568
NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117
G
Erbb2
erb-b2 receptor tyrosine kinase 2
disease_progression
ISO
associated with Breast Neoplasms;DNA, protein:polymorphism, increased expression:serum:p.I655V associated with lung adenocarcinoma; protein:increased expression:lung (human) CTD Direct Evidence: marker/mechanism associated with Carcinoma, Transitional Cell;protein:increased expression:urinary bladder
RGD CTD
PMID:21532492 PMID:21966491 PMID:18237248 PMID:18097576
RGD:153344600 , RGD:2289925 , RGD:2289926
NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
G
Erbb3
erb-b2 receptor tyrosine kinase 3
ISO
associated with Prostatic Neoplasms;protein:increased expression, altered localization:lymph node, nucleus associated with head and neck squamous cell carcinoma
RGD
PMID:17634423 PMID:20604875
RGD:2289944 , RGD:126790467
NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525
G
Erbb4
erb-b2 receptor tyrosine kinase 4
disease_progression severity
ISO
associated with oral squamous cell carcinoma associated with lung non-small cell carcinoma associated with colorectal adenocarcinoma
RGD
PMID:27444519 PMID:21324275 PMID:16507107
RGD:126781762 , RGD:126790471 , RGD:126781766
NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
G
Fas
Fas cell surface death receptor
susceptibility
ISO
associated with Cervix Neoplasms;DNA:polymorphism:promoter:-1377G>A
RGD
PMID:18068525
RGD:2298509
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
G
Fgf1
fibroblast growth factor 1
ISO
associated with Cervix Neoplasms;mRNA:increased expression:lymph node
RGD
PMID:17242701
RGD:2290286
NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
G
Fgfr2
fibroblast growth factor receptor 2
ISO
associated with breast cancer;DNA:snp:intron:c.109+7033T>A (rs1219648) (human)
RGD
PMID:20640597
RGD:7394846
NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
G
Flt3
Fms related receptor tyrosine kinase 3
disease_progression
ISO
associated with Prostatic Neoplasms
RGD
PMID:14566827
RGD:2302210
NCBI chr12:7,623,930...7,699,474
Ensembl chr12:7,623,930...7,699,474
G
Foxa1
forkhead box A1
ISO
associated with lung non-small cell carcinoma; mRNA:increased expression: :
RGD
PMID:29115441
RGD:151665751
NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
G
Foxp1
forkhead box P1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25485836
NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258
G
Gpx3
glutathione peroxidase 3
ISO
associated with stomach carcinoma; DNA:hypermethylation:promoter
RGD
PMID:23071548
RGD:151665353
NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
G
Grik2
glutamate ionotropic receptor kainate type subunit 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30705370
NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375
G
Hmgb1
high mobility group box 1
IEP
associated with Adenocarcinoma, Colon
RGD
PMID:20616616
RGD:10402080
NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565 Ensembl chr16:5,901,586...5,978,565
G
Icam1
intercellular adhesion molecule 1
ISO
associated with Breast Neoplasms
RGD
PMID:21590495
RGD:8547712
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
G
Ier2
immediate early response 2
IMP
RGD
PMID:22120713
RGD:153323322
NCBI chr19:23,494,551...23,496,075
Ensembl chr19:23,494,184...23,499,211
G
Il13
interleukin 13
ISO
associated with Melanoma, Cutaneous Malignant;mRNA:increased expression:lymph node
RGD
PMID:17545514
RGD:8549587
NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
G
Il18
interleukin 18
ISO
associated with Breast Neoplasms;protein:increased expression:serum
RGD
PMID:12902898
RGD:8655867
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
G
Ing4
inhibitor of growth family, member 4
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:27806345
NCBI chr 4:157,841,882...157,850,519
Ensembl chr 4:157,841,951...157,850,265
G
Iqsec1
IQ motif and Sec7 domain ArfGEF 1
disease_progression
ISO
associated with lung adenocarcinoma; protein:increased expression:lung (human)
RGD
PMID:21966491
RGD:153344600
NCBI chr 4:123,168,719...123,488,300
Ensembl chr 4:123,168,719...123,488,172
G
Itgb1
integrin subunit beta 1
ISO
associated with non-small cell lung carcinoma,
RGD
PMID:28537888
RGD:13792830
NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
G
Kcnj12
potassium inwardly-rectifying channel, subfamily J, member 12
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:34755307
NCBI chr10:45,696,621...45,745,528
Ensembl chr10:45,696,849...45,745,492
G
Kdr
kinase insert domain receptor
treatment
ISO
associated with Squamous Cell Carcinoma of the Tongue
RGD
PMID:19380367
RGD:8551769
NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
G
Kiss1
KiSS-1 metastasis-suppressor
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:21383688
NCBI chr13:44,775,106...44,780,707
Ensembl chr13:44,774,823...44,780,612
G
Klf7
KLF transcription factor 7
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:37734194
NCBI chr 9:65,433,683...65,526,372
Ensembl chr 9:65,437,167...65,526,261
G
Kmt2d
lysine methyltransferase 2D
ISO
associated with stomach cancer
RGD
PMID:30177394
RGD:150521710
NCBI chr 7:129,980,744...130,022,088
Ensembl chr 7:129,962,887...130,020,325
G
Lamc2
laminin subunit gamma 2
ISO
associated with lung squamous cell carcinoma;
RGD
PMID:23124251
RGD:13793371
NCBI chr13:65,284,664...65,344,164
Ensembl chr13:65,284,664...65,344,200
G
Lrrc59
leucine rich repeat containing 59
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30705370
NCBI chr10:79,572,295...79,586,953
Ensembl chr10:79,572,317...79,602,533
G
Macir
macrophage immunometabolism regulator
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30705370
NCBI chr 9:98,420,760...98,440,818
Ensembl chr 9:98,420,376...98,441,733
G
Met
MET proto-oncogene, receptor tyrosine kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:29426936
NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
G
Mir125a
microRNA 125a
ISO
associated with stomach cancer;
RGD
PMID:22322911
RGD:21408544
NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710
G
Mir152
microRNA 152
ISO
associated with breast cancer
RGD
PMID:22935141
RGD:19165152
NCBI chr10:81,832,936...81,833,020
Ensembl chr10:81,832,936...81,833,020
G
Mir155
microRNA 155
disease_progression
ISO
associated with colon cancer
RGD
PMID:26885061 PMID:29893326 PMID:27856635
RGD:21079444 , RGD:21409756 , RGD:21079446
NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
G
Mir187
microRNA 187
ISO
associated with oral squamous cell carcinoma; RNA:increased expression:plasma
RGD
PMID:27542258
RGD:14390167
NCBI chr18:15,731,194...15,731,297
Ensembl chr18:15,731,194...15,731,297
G
Mir224
microRNA 224
ISO
associated with colorectal cancer; mRNA:decreased expression:colorectal mucosa:
RGD
PMID:25919696
RGD:14398749
NCBI chr X:150,065,088...150,065,169
Ensembl chr X:150,065,088...150,065,169
G
Mir30a
microRNA 30a
ISO
associated with Colorectal Neoplasms
RGD
PMID:23486085
RGD:13432035
NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670
G
Mmp2
matrix metallopeptidase 2
disease_progression
ISO
associated with Tongue Neoplasms associated with Carcinoma, Ductal, Breast
RGD
PMID:23107277 PMID:23280016
RGD:8547824 , RGD:8655998
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
G
Mmp3
matrix metallopeptidase 3
susceptibility
ISO
associated with breast cancer;DNA:deletion:promoter:-1170_-1172delA (human)
RGD
PMID:15161710 PMID:15161710
RGD:8662937 , RGD:8662937
NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
G
Mmp9
matrix metallopeptidase 9
disease_progression
ISO
associated with Carcinoma, Non-Small-Cell Lung;protein:increased expression:serum associated with Tongue Neoplasms associated with Endometrial Neoplasms;protein:increased expression:endometrium
RGD
PMID:20704821 PMID:23107277 PMID:12487935
RGD:5129215 , RGD:8547824 , RGD:2298523
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
G
Msh2
mutS homolog 2
ISO
associated with laryngeal squamous cell carcinoma
RGD
PMID:24459922
RGD:126848797
NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
G
Msln
mesothelin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22644300
NCBI chr10:14,771,946...14,781,382
Ensembl chr10:14,771,961...14,777,643
G
Mt1
metallothionein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17418620
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049
G
Mta1
metastasis associated 1
ISO
associated with Carcinoma, Non-Small-Cell Lung;mRNA:increased expression:lung
RGD
PMID:11804687
RGD:9588220
NCBI chr 6:132,178,608...132,217,641
Ensembl chr 6:132,178,853...132,217,641
G
Mtor
mechanistic target of rapamycin kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30705370
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
G
Muc1
mucin 1, cell surface associated
ISO
associated with Common Bile Duct Neoplasms associated with Esophageal Neoplasms associated with Carcinoma, Renal Cell; associated with Gallbladder Neoplasms;protein:altered localization:gallbladder
RGD
PMID:16222735 PMID:21339746 PMID:10390012 PMID:11295067
RGD:2324649 , RGD:7349383 , RGD:7245968 , RGD:2324860
NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733
G
Muc5ac
mucin 5AC, oligomeric mucus/gel-forming
ISO
associated with chloangiocarcinoma;protein:increased expression:bile duct
RGD
PMID:16842244
RGD:2325168
NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475
G
Ncam1
neural cell adhesion molecule 1
ISO
RGD
PMID:10086383
RGD:2326067
NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014
G
Nme1
NME/NM23 nucleoside diphosphate kinase 1
ISO
associated with Cervix Neoplasms; associated with Endometrial Neoplasms associated with Breast Neoplasms
RGD
PMID:8855975 PMID:8102131 PMID:9036878
RGD:2299062 , RGD:2299077 , RGD:2299061
NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408
G
Nme2
NME/NM23 nucleoside diphosphate kinase 2
ISO
associated with Cervix Neoplasms; associated with Endometrial Neoplasms
RGD
PMID:8855975
RGD:2299062
NCBI chr10:78,898,097...78,903,514
Ensembl chr10:78,897,770...78,903,538
G
Nos3
nitric oxide synthase 3
susceptibility
ISO
associated with Breast Neoplasms;DNA:polymorphisms:promoter, exon:-786T>C,p.E298D (human)
RGD
PMID:17262178
RGD:2292070
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
G
Ogg1
8-oxoguanine DNA glycosylase
ISO
associated with breast cancer;DNA:missense mutation:cds:p.S326C (rs1052133) (human)
RGD
PMID:18977234
RGD:8657156
NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
G
Pagr1
Paxip1-associated glutamate-rich protein 1
disease_progression
ISO
protein:decreased expression:esophagus (human)
RGD
PMID:33833989
RGD:153344568
NCBI chr 1:181,622,698...181,625,024
G
Pdgfa
platelet derived growth factor subunit A
ISO
associated with Breast Neoplasms;mRNA:increased expression:breast
RGD
PMID:8619189
RGD:2292155
NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
G
Pdgfb
platelet derived growth factor subunit B
ISO
associated with Breast Neoplasms;mRNA:increased expression:lymph node
RGD
PMID:17674348
RGD:2292173
NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
G
Pdpk1
3-phosphoinositide dependent protein kinase-1
ISO
associated with non-small cell lung carcinoma;mRNA:increased expression:blood serum
RGD
PMID:25064732
RGD:13503320
NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623
G
Pdpn
podoplanin
ISO
associated with Breast Neoplasms associated with Cervix Neoplasms
RGD
PMID:18165897 PMID:16528371
RGD:2292231 , RGD:2292237
NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656
G
Pebp1
phosphatidylethanolamine binding protein 1
ISO
associated with Breast Neoplasms associated with Cervix Neoplasms
RGD
PMID:16243812 PMID:18191186
RGD:2302868 , RGD:2302867
NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
G
Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
ISO
associated with Colorectal Neoplasms
RGD
PMID:25550888
RGD:13432030
NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
G
Pik3cb
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
ISO
associated with Colorectal Neoplasms
RGD
PMID:25550888
RGD:13432030
NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663
G
Pip5k1a
phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:34755307
NCBI chr 2:182,628,299...182,671,584
Ensembl chr 2:182,628,300...182,671,598
G
Pou5f1
POU class 5 homeobox 1
ISO
associated with Seminoma; associated with Carcinoma, Embryonal
RGD
PMID:15386301
RGD:2292442
NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
G
Pparg
peroxisome proliferator-activated receptor gamma
ISO
associated with Cholangiocarcinoma;protein:increased expression:bile duct epithelium
RGD
PMID:20021832
RGD:2317459
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
G
Prex1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
ISO
associated with Prostatic Neoplasms
RGD
PMID:19305425
RGD:2314605
NCBI chr 3:155,306,950...155,456,688
Ensembl chr 3:155,306,950...155,456,688
G
Pten
phosphatase and tensin homolog
ISO
associated with Prostatic Neoplasms;protein:decreased expression:prostate associated with Breast Neoplasms
RGD
PMID:17163422 PMID:17919877
RGD:2292507 , RGD:2292499
NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
G
Ptgs2
prostaglandin-endoperoxide synthase 2
ISO
associated with Biliary Tract Neoplasms associated with carcinoma, non-small-cell lung; DNA:SNP: :929G>C(human) associated with Breast Neoplasms
RGD
PMID:18159174 PMID:20016751 PMID:18353210
RGD:2317165 , RGD:5135471 , RGD:2300128
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
G
Ptk2
protein tyrosine kinase 2
ISO
associated with lung squamous cell carcinoma; protein:increased tyrosine phosphorylation:lymph node
RGD
PMID:23906871
RGD:152176664
NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
G
Ptpn13
protein tyrosine phosphatase, non-receptor type 13
ISO
associated with lung squamous cell carcinoma; protein:decreased expression:lymph node
RGD
PMID:23906871
RGD:152176664
NCBI chr14:6,108,202...6,282,619
Ensembl chr14:6,108,211...6,282,563
G
Ramp2
receptor activity modifying protein 2
disease_progression
ISO
associated with colorectal cancer; protein:increased expression:lymph node (human)
RGD
PMID:23634287
RGD:151708733
NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829
G
Ramp3
receptor activity modifying protein 3
ISO
associated with colorectal cancer; protein:increased expression:lymph node (human)
RGD
PMID:23634287
RGD:151708733
NCBI chr14:81,527,404...81,544,905
Ensembl chr14:81,527,385...81,544,902
G
Rassf2
Ras association domain family member 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17013896
NCBI chr 3:119,244,288...119,280,462
Ensembl chr 3:119,245,821...119,280,431
G
Rbm10
RNA binding motif protein 10
ISO
associated with lung adenocarcinoma;DNA:missense mutation:exon:p.R241C (c.763C>T) (human)
RGD
PMID:30405763
RGD:151356993
NCBI chr X:1,540,399...1,572,571
Ensembl chr X:1,540,398...1,572,575
G
Rela
RELA proto-oncogene, NF-kB subunit
ISO
associated with Prostatic Neoplasms;protein:altered localization:nucleus, prostate gland
RGD
PMID:17020979
RGD:2298757
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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Ret
ret proto-oncogene
ISO
associated with Pancreatic Neoplasms
RGD
PMID:18652760
RGD:2324925
NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176
G
Rhoa
ras homolog family member A
ISO
associated with Bladder Neoplasms;protein:increased expression:lymph node associated with colorectal cancer
RGD
PMID:12855641 PMID:17597401
RGD:2298872 , RGD:13432052
NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
G
Rictor
RPTOR independent companion of MTOR, complex 2
ISO
associated with breast ductal carcinoma; protein:increased expression:breast tumor, lymph node (human)
RGD
PMID:20978191
RGD:152995469
NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426
G
Runx1
RUNX family transcription factor 1
ISO
associated with Carcinoid Tumor
RGD
PMID:21636701
RGD:126779567
NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542
G
Sfn
stratifin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19381893
NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314
G
Skp2
S-phase kinase associated protein 2
ISO
associated with Endometrial Neoplasms;protein:increased expression:endometrium
RGD
PMID:16080017
RGD:2315043
NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338
G
Slc22a22
solute carrier family 22 member 22
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30705370
NCBI chr 7:88,720,425...88,750,111
Ensembl chr 7:88,720,427...88,750,111
G
Slc7a5
solute carrier family 7 member 5
severity
ISO
associated with stomach carcinoma associated with gastric adenocarcinoma;protein:increased expression: :
RGD
PMID:25908107 PMID:21501294
RGD:11052781 , RGD:151361203
NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
G
Smad4
SMAD family member 4
ISO
associated with Breast Neoplasms
RGD
PMID:11809701
RGD:2300007
NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
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Smo
smoothened, frizzled class receptor
ISO
associated with colorectal cancer
RGD
PMID:30784110
RGD:150520177
NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829
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Sncg
synuclein, gamma
ISO
RGD
PMID:15221989
RGD:6478801
NCBI chr16:9,700,513...9,705,751
Ensembl chr16:9,700,514...9,705,368
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Socs2
suppressor of cytokine signaling 2
ISO
associated with Prostatic Neoplasms
RGD
PMID:16707422
RGD:2298925
NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548
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Socs3
suppressor of cytokine signaling 3
ISO
associated with Breast Neoplasms
RGD
PMID:18097573
RGD:2298901
NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
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Sod2
superoxide dismutase 2
disease_progression
ISO
associated with tongue neoplasms; CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:10853026 PMID:19381893 PMID:20618948 PMID:20618948
RGD:8547519
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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Sox2
SRY-box transcription factor 2
disease_progression
ISO
associated with Breast Neoplasms
RGD
PMID:24382260
RGD:8661670
NCBI chr 2:117,536,929...117,539,340
Ensembl chr 2:117,536,929...117,539,338
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Src
SRC proto-oncogene, non-receptor tyrosine kinase
ISO
associated with colon adenocarcinoma,
RGD
PMID:21282564
RGD:150520218
NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
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St14
ST14 transmembrane serine protease matriptase
ISO
associated with Endometrial Neoplasms
RGD
PMID:19443387
RGD:2315087
NCBI chr 8:29,540,805...29,581,704
Ensembl chr 8:29,540,811...29,581,517
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Stat3
signal transducer and activator of transcription 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21549414
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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Stk11
serine/threonine kinase 11
ISO
associated with Breast Neoplasms;protein:decreased expression
RGD
PMID:12114407
RGD:2291948
NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
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Tert
telomerase reverse transcriptase
disease_progression
ISO
associated with lung non-small cell carcinoma;
RGD
PMID:11679180
RGD:152977755
NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561
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Timp1
TIMP metallopeptidase inhibitor 1
ISO
associated with Endometrial Neoplasms;protein:increased expression:endometrium
RGD
PMID:12487935
RGD:2298523
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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Timp3
TIMP metallopeptidase inhibitor 3
ISO
associated with Breast Neoplasms;mRNA:increased expression:breast
RGD
PMID:12828172
RGD:2290437
NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839
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Timp4
TIMP metallopeptidase inhibitor 4
ISO
associated with Breast Neoplasms;mRNA:increased expression:breast
RGD
PMID:12828172
RGD:2290437
NCBI chr 4:148,306,021...148,312,558
Ensembl chr 4:148,304,490...148,312,558
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Tlr4
toll-like receptor 4
ISO
associated with Carcinoma, Ductal, Breast;
RGD
PMID:23338716
RGD:7794684
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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Tp53
tumor protein p53
ISO
associated with Penile Neoplasms associated with Carcinoma, Squamous Cell; associated with Breast Neoplasms;DNA:missense mutation, duplication:cds, intron:p.R72P
RGD
PMID:18268397 PMID:18059331 PMID:18230179
RGD:2290533 , RGD:8547790 , RGD:2290534
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Tp53bp1
tumor protein p53 binding protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30705370
NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822
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Trmt11
tRNA methyltransferase 11 homolog
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30705370
NCBI chr 1:27,054,437...27,109,765
Ensembl chr 1:27,054,420...27,201,610
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Tsc2
TSC complex subunit 2
ISO
associated with Breast Neoplasms
RGD
PMID:15951164
RGD:11568707
NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951
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Tshr
thyroid stimulating hormone receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:9062474
NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538
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Ttr
transthyretin
ISO
associated with colorectal cancer;protein:decreased expresion:blood serum (human)
RGD
PMID:21074777
RGD:151665155
NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
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Tymp
thymidine phosphorylase
ISO
associated with Cholangiocarcinoma associated with Breast Neoplasms
RGD
PMID:11927969 PMID:10685502
RGD:2325027 , RGD:2293725
NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874 Ensembl chr 7:120,438,770...120,443,874
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Vegfa
vascular endothelial growth factor A
ISO
associated with Cervix Neoplasms associated with Breast neoplasms;
RGD
PMID:19783962 PMID:17597103
RGD:2315454 , RGD:7421574
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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Vegfc
vascular endothelial growth factor C
exacerbates disease_progression
ISO
associated with Carcinoma, Transitional Cell;protein:increased expression:urinary bladder associated with pancreatic adenocarcinoma;protein:increased expression:pancreas (human) associated with Lymphatic Metastasis; associated with thyroid diseases;mRNA:increased expression:thyroid gland: associated with Breast Neoplasms associated with Prostatic Neoplasms associated with Cervix Neoplasms
RGD
PMID:17034609 PMID:18061373 PMID:15289890 PMID:12203051 PMID:19923084 PMID:19608016 PMID:19589137 More...
RGD:2315484 , RGD:155630642 , RGD:7488946 , RGD:7483611 , RGD:2315469 , RGD:2315474 , RGD:2315475
NCBI chr16:37,712,251...37,827,845
Ensembl chr16:37,712,262...37,827,848
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Vegfd
vascular endothelial growth factor D
ISO
associated with Breast Neoplasms associated with Cervix Neoplasms
RGD
PMID:17951197 PMID:19589137
RGD:2315480 , RGD:2315475
NCBI chr X:30,073,122...30,108,413
Ensembl chr X:30,074,163...30,108,295
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Wrap53
WD repeat containing, antisense to TP53
ISO
associated with lung non-small cell carcinoma; associated with esophagus squamous cell carcinoma;
RGD
PMID:31281482 PMID:24626331
RGD:21081513 , RGD:21081532
NCBI chr10:54,282,092...54,299,908
Ensembl chr10:54,282,105...54,298,929
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Cycs
cytochrome c, somatic
ISO
associated with non-small cell lung carcinoma; protein:decreased expression:serum
RGD
PMID:25578497
RGD:13792769
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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Cdh1
cadherin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27224422
NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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