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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Neoplasm Metastasis
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Accession:DOID:9000965 term browser browse the term
Definition:The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.
Synonyms:exact_synonym: Metastases;   Metastasis;   Neoplasm Metastases
 primary_id: MESH:D009362
 xref: EFO:0009708;   EFO:0009709;   EFO:0010941



show annotations for term's descendants           Sort by:
Neoplasm Metastasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:12015757 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17003774 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Ace angiotensin I converting enzyme ISO CTD Direct Evidence: marker/mechanism CTD PMID:18059164 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Ackr3 atypical chemokine receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22180778 NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237
JBrowse link
G Acsbg1 acyl-CoA synthetase bubblegum family member 1 ISO associated with pheochromocytoma RGD PMID:29067245 RGD:13831131 NCBI chr 8:54,991,294...55,047,276
Ensembl chr 8:54,991,296...55,047,391
JBrowse link
G Acvr2a activin A receptor type 2A exacerbates ISO associated with colon cancer;mRNA,protein:decreased expression:colon (human) RGD PMID:30310521 RGD:151361136 NCBI chr 3:33,204,961...33,292,673
Ensembl chr 3:33,205,523...33,289,968
JBrowse link
G Adgrb1 adhesion G protein-coupled receptor B1 ISO associated with colorectal cancer RGD PMID:9772287 RGD:13831353 NCBI chr 7:106,404,827...106,476,902
Ensembl chr 7:106,404,958...106,476,902
JBrowse link
G Adora2b adenosine A2B receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27590504 NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772
JBrowse link
G Agtr1a angiotensin II receptor, type 1a ISO CTD Direct Evidence: marker/mechanism CTD PMID:18059164 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Agtr2 angiotensin II receptor, type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18059164 NCBI chr  X:112,119,876...112,124,060
Ensembl chr  X:112,120,228...112,124,057
JBrowse link
G Ahr aryl hydrocarbon receptor ISO CTD Direct Evidence: therapeutic CTD PMID:21948867 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akirin2 akirin 2 IMP RGD PMID:18460465 RGD:2306009 NCBI chr 5:49,108,231...49,122,566
Ensembl chr 5:49,108,220...49,122,568
JBrowse link
G Akt2 AKT serine/threonine kinase 2 ISO associated with Mammary Neoplasms, Experimental RGD PMID:19491266 RGD:2315599 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A ISO CTD Direct Evidence: marker/mechanism CTD PMID:20562527 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
JBrowse link
G Alk ALK receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22986231 PMID:22999080 NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034
JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20061081 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Amigo2 adhesion molecule with Ig like domain 2 ISO Liver Metastasis RGD PMID:28272394 RGD:14394499 NCBI chr 7:128,391,493...128,394,589
Ensembl chr 7:128,390,412...128,394,695
JBrowse link
G Angptl4 angiopoietin-like 4 ISO CTD Direct Evidence: therapeutic CTD PMID:17130448 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Antxr1 ANTXR cell adhesion molecule 1 ISO associated with Mammary Neoplasms, Experimental; RGD PMID:22085271 RGD:9684855 NCBI chr 4:119,590,770...119,778,232
Ensembl chr 4:119,590,771...119,778,232
JBrowse link
G Anxa1 annexin A1 treatment IEP
ISO
IMP
associated with Mammary Neoplasms, Experimental;protein:increased expression:lung
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:20308542 PMID:9514092 PMID:20821804 PMID:20821804 PMID:20308542 RGD:2306939, RGD:7421541, RGD:7421541, RGD:7421563 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Anxa4 annexin A4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161
JBrowse link
G Anxa7 annexin A7 ISO associated with Breast Neoplasms;protein:increased expression:breast
associated with Prostatic Neoplasms;protein:decreased expression:prostate gland
RGD PMID:15073110 PMID:11287641 RGD:2292655, RGD:2292656 NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385
JBrowse link
G Apoe apolipoprotein E ISO RGD PMID:22469977 RGD:7771597 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:20562527 NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023
JBrowse link
G Arid1a AT-rich interaction domain 1A disease_progression ISO in lung; associated with hepatocellular carcinoma RGD PMID:25975202 RGD:125097495 NCBI chr 5:145,908,173...145,981,552
Ensembl chr 5:145,908,181...145,985,564
JBrowse link
G Atp6v1c1 ATPase H+ transporting V1 subunit C1 ISO associated with Mammary Neoplasms, Experimental RGD PMID:24155661 RGD:14700647 NCBI chr 7:69,834,464...69,872,278
Ensembl chr 7:69,834,463...69,872,278
JBrowse link
G Axl Axl receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26206560 NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265
JBrowse link
G Azin1 antizyme inhibitor 1 ISO associated with stomach cancer;RNA:increased editing:stomach
associated with colorectal cancer;RNA:increased editing:colorectum
RGD PMID:30563560 PMID:29925690 RGD:14700703, RGD:14700704 NCBI chr 7:69,654,773...69,681,578
Ensembl chr 7:69,654,663...69,681,578
JBrowse link
G Bax BCL2 associated X, apoptosis regulator ISO associated with Carcinoma, Infiltrating Duct RGD PMID:17288732 RGD:1643356 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator ISO associated with Breast Neoplasms
associated with Carcinoma, Renal Cell
RGD PMID:16826579 PMID:12810203 RGD:2293020, RGD:2293021 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bmp6 bone morphogenetic protein 6 severity ISO associated with Prostatic Neoplasms;protein:increased expression:bone RGD PMID:16166304 RGD:2289018 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Bmp7 bone morphogenetic protein 7 disease_progression ISO associated with Breast Neoplasms;protein:increased expression:breast
associated with Prostatic Neoplasms;mRNA:increased expression:bone
RGD PMID:17895257 PMID:12539225 RGD:2289029, RGD:2289033 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase onset ISO associated with Melanoma; DNA:mutations: : RGD PMID:25623140 RGD:11567259 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Brd4 bromodomain containing 4 ISO RGD PMID:23950209 RGD:9586346 NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539
JBrowse link
G Brms1 BRMS1, transcriptional repressor and anoikis regulator ISO CTD Direct Evidence: therapeutic CTD PMID:27501413 NCBI chr 1:202,345,766...202,355,028
Ensembl chr 1:202,345,704...202,355,028
JBrowse link
G Bsg basigin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21956400 NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387
JBrowse link
G Cab39 calcium binding protein 39 ISO associated with hepatocellular carcinoma; RGD PMID:28605041 RGD:14398832 NCBI chr 9:86,463,095...86,524,545
Ensembl chr 9:86,463,095...86,524,544
JBrowse link
G Cacybp calcyclin binding protein ISO associated with pancreatic neoplasms RGD PMID:18765951 RGD:2326146 NCBI chr13:72,437,485...72,447,810
Ensembl chr13:72,437,490...72,450,177
JBrowse link
G Calml3 calmodulin-like 3 ameliorates ISO associated with hepatocellular carcinoma; human cells in mouse model
associated with hepatocellular carcinoma; protein:decreased expression:liver (human)
RGD PMID:29445139 PMID:29445139 RGD:151665319, RGD:151665319 NCBI chr17:66,419,844...66,423,083
Ensembl chr17:66,419,882...66,423,175
JBrowse link
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 ISO associated with Pancreatic Neoplasms; mRNA, protein:increased expression:pancreas RGD PMID:19188911 RGD:2326238 NCBI chr 5:135,142,108...135,168,885
Ensembl chr 5:135,142,112...135,168,769
JBrowse link
G Casp3 caspase 3 ISO associated with Breast Neoplasms RGD PMID:18064531 RGD:2293306 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase ISO CTD Direct Evidence: therapeutic CTD PMID:12538496 PMID:22580338 PMID:23518002 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cav1 caveolin 1 treatment ISO associated with Mammary Neoplasms, Experimental
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:20562527 PMID:15355971 PMID:15334058 RGD:2289106, RGD:8661780 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cbx4 chromobox 4 ISO associated with Carcinoma, Hepatocellular; RGD PMID:24838576 RGD:9586738 NCBI chr10:104,337,140...104,343,210
Ensembl chr10:104,336,876...104,356,706
JBrowse link
G Cbx5 chromobox 5 ISO associated with Lung Neoplasms; RGD PMID:22900142 RGD:9586743 NCBI chr 7:134,333,165...134,376,102
Ensembl chr 7:134,331,335...134,375,022
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 ISO associated with Mammary Neoplasms, Experimental RGD PMID:19629725 RGD:4891450 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30603057 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO RGD PMID:18941229 RGD:7241810 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 treatment ISO associated with Animal Mammary Neoplasms; RGD PMID:15692764 RGD:14995455 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccn4 cellular communication network factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30723155 NCBI chr 7:98,645,238...98,677,253
Ensembl chr 7:98,645,182...98,677,248
JBrowse link
G Ccna2 cyclin A2 ISO associated with Seminoma;protein:increased expression:testis RGD PMID:14696091 RGD:2293346 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnd1 cyclin D1 treatment ISO associated with Carcinoma, Non-Small-Cell Lung;mRNA:splice variant
associated with stomach cancer; human cells in mouse model
RGD PMID:18715616 PMID:27431311 RGD:13434926, RGD:152995400 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 ISO associated with Breast Neoplasms;DNA:hypermethylated:brain RGD PMID:15131050 RGD:2289155 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccne1 cyclin E1 disease_progression ISO protein:altered processing
associated with non-small cell lung carcinoma
RGD PMID:17671189 PMID:11212263 RGD:2289229, RGD:13673913 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35072892 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
JBrowse link
G Cd274 CD274 molecule disease_progression ISO associated with ovarian cancer RGD PMID:23340297 RGD:41410797 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450
JBrowse link
G Cd44 CD44 molecule ISO associated with Carcinoma, Renal Cell;protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism
associated with Breast Neoplasm;protein:increased expression:liver
CTD
RGD
PMID:23098472 PMID:18026989 PMID:17991717 RGD:2289347, RGD:2289349 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd82 Cd82 molecule IEP
ISO
associated with Carcinoma, Hepatocellular;mRNA:decreased expression
CTD Direct Evidence: therapeutic
associated with Prostatic Neoplasms;mRNA:decreased expression:bone
associated with Carcinoma, Infiltrating Duct;mRNA:decreased expression:brain
associated with Prostatic Neoplasms;DNA:loss of heterozygosity
CTD
RGD
PMID:20075392 PMID:11275982 PMID:12806379 PMID:15592684 PMID:9831222 More... RGD:2289407, RGD:2289402, RGD:2289400, RGD:68869, RGD:2289425 NCBI chr 3:79,387,361...79,431,847
Ensembl chr 3:79,385,887...79,431,809
JBrowse link
G Cd86 CD86 molecule IEP mRNA:decreased expression:mediastinal lymph node (rat) RGD PMID:18360875 RGD:4892237 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cdh1 cadherin 1 treatment ISO associated with Prostatic Neoplasms
associated with stomach cancer; human cells in mouse model
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:17520682 PMID:22580338 PMID:18008331 PMID:27431311 RGD:2289488, RGD:152995400 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdh2 cadherin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23876460 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cdkl2 cyclin dependent kinase like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25333262 NCBI chr14:16,027,381...16,063,257
Ensembl chr14:16,028,363...16,063,252
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A ISO associated with Melanoma; RGD PMID:9194578 RGD:8662817 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO associated with Paraganglioma, Extra-Adrenal;DNA:hypermethylation RGD PMID:18509008 RGD:8552280 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cfl1 cofilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20562527 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
JBrowse link
G Cga glycoprotein hormones, alpha polypeptide ISO associated with Breast Neoplasms;protein:increased expression:serum RGD PMID:6768680 RGD:2293637 NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
JBrowse link
G Chek1 checkpoint kinase 1 ISO associated with Pancreatic Neoplasms RGD PMID:15448002 RGD:2317235 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex ISO associated with prostate adenocarcinoma RGD PMID:17377533 RGD:2298657 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Cic capicua transcriptional repressor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27869830 NCBI chr 1:80,853,920...80,880,537
Ensembl chr 1:80,853,920...80,880,532
JBrowse link
G Cldn7 claudin 7 IMP RGD PMID:23390083 RGD:9685143 NCBI chr10:54,689,684...54,692,177
Ensembl chr10:54,689,987...54,692,171
JBrowse link
G Clic1 chloride intracellular channel 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20562527 NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712
JBrowse link
G Clu clusterin ISO associated with Breast Neoplasms RGD PMID:20307318 RGD:8883512 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Creb1 cAMP responsive element binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29179997 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Csf1 colony stimulating factor 1 ISO associated with Prostatic Neoplasms RGD PMID:18510570 RGD:2293638 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
JBrowse link
G Csf1r colony stimulating factor 1 receptor exacerbates ISO associated with Prostatic Neoplasms
associated with breast cancer
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:1390197 PMID:18510570 PMID:25005824 RGD:2293638, RGD:150524287 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Csf3 colony stimulating factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:7543699 PMID:9018096 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
JBrowse link
G Cst3 cystatin C ISO protein:decreased expression:cerebrospinal fluid RGD PMID:12589965 RGD:5686394 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
JBrowse link
G Csta cystatin A ISO CTD Direct Evidence: marker/mechanism CTD PMID:20461718 NCBI chr11:64,620,483...64,631,488
Ensembl chr11:64,620,483...64,631,488
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 disease_progression ISO associated with Mammary Neoplasms, Experimental RGD PMID:15701862 PMID:18049334 RGD:4891518, RGD:7204722 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963
JBrowse link
G Ctnnb1 catenin beta 1 ISO associated with Prostatic Neoplasms
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:29106415 PMID:18008331 RGD:2289488 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctsb cathepsin B ISO protein:increased expression:cerebrospinal fluid RGD PMID:12589965 RGD:5686394 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Ctsd cathepsin D ISO protein:increased expression:oral cavity, oropharynx, hypopharynx (human) RGD PMID:10562684 RGD:1547892 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Ctsh cathepsin H ISO protein:increased expression:cerebrospinal fluid RGD PMID:12589965 RGD:5686394 NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824
JBrowse link
G Ctu1 cytosolic thiouridylase subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27811057 NCBI chr 1:94,115,431...94,121,224
Ensembl chr 1:94,115,420...94,121,221
JBrowse link
G Ctu2 cytosolic thiouridylase subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27811057 NCBI chr19:50,539,184...50,544,629
Ensembl chr19:50,539,352...50,544,623
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 susceptibility ISO associated with Breast Neoplasms RGD PMID:16627550 RGD:4892015 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 treatment ISO associated with Pancreatic Neoplasms
CTD Direct Evidence: marker/mechanism
associated with Pancreatic Carcinoma
CTD
RGD
PMID:21312072 PMID:23743303 PMID:12761880 PMID:26330165 RGD:2317610, RGD:10398726 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 ISO associated with Mammary Neoplasms, Experimental RGD PMID:16885372 RGD:5135487 NCBI chr  X:66,844,318...66,846,969
Ensembl chr  X:66,844,318...66,846,969
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ameliorates
severity
disease_progression
ISO CTD Direct Evidence: marker/mechanism
associated with lung non-small cell carcinoma;mRNA,protein:increased expression:lung (human)
associated with Otorhinolaryngologic Neoplasms;mRNA,protein:increased expression:Laryngeal and hypopharyngeal tissue (human)
associated with lung non-small cell carcinoma; protein:increased expression:lung (human)
associated with oral squamous cell carcinoma
associated with pancreatic cancer
associated with osteosarcoma;protein:increased expression:bone (human)
human cells in mouse model;associated with lung cancer
associated with lung cancer; human cells in mouse model
CTD
RGD
PMID:21312072 PMID:23743303 PMID:26546437 PMID:16322285 PMID:18487224 More... RGD:152023746, RGD:152177479, RGD:152177478, RGD:152177476, RGD:152177475, RGD:152025556, RGD:152023745, RGD:152023741, RGD:151708730 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28112739 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Dab2ip DAB2 interacting protein severity ISO associated with colorectal cancer;protein:decreased expression:colorectum (human) RGD PMID:26336990 RGD:11531913 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280
JBrowse link
G Dapk1 death associated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17319784 NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991
JBrowse link
G Daxx death-domain associated protein ISO RGD PMID:23539629 RGD:9587820 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
JBrowse link
G Dcn decorin ISO associated with Breast Neoplasms RGD PMID:18688028 RGD:2311418 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 severity ISO mRNA:increased expression:ovary (human)
protein:increased expression:bone (human)
RGD PMID:28743276 PMID:29039472 RGD:151347541, RGD:151347601 NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 ameliorates ISO associated with melanoma; RGD PMID:24293323 RGD:150429711 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked ISO human cells in mouse model RGD PMID:26087195 RGD:11096798 NCBI chr  X:9,479,532...9,493,169
Ensembl chr  X:9,479,532...9,493,168
JBrowse link
G Dek DEK proto-oncogene ISO CTD Direct Evidence: marker/mechanism CTD PMID:27811057 NCBI chr17:17,580,804...17,602,825
Ensembl chr17:17,580,843...17,602,808
JBrowse link
G Dhfr dihydrofolate reductase disease_progression IEP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19159907 PMID:8149482 RGD:11040442 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
JBrowse link
G Dio3 iodothyronine deiodinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26825960 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660
JBrowse link
G Dmd dystrophin ISO CTD Direct Evidence: marker/mechanism CTD PMID:24793134 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta ISO associated with Uterine Cervical Neoplasms; RGD PMID:22330137 RGD:9589117 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase treatment ISO associated with Colonic Neoplasms
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:17611699 PMID:11383214 RGD:11251755 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
JBrowse link
G E2f1 E2F transcription factor 1 severity ISO protein:increased expression:bone (human) RGD PMID:29039472 RGD:151347601 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
JBrowse link
G E2f8 E2F transcription factor 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27683099 NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098
JBrowse link
G Edn1 endothelin 1 ISO RGD PMID:12941866 RGD:734914 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ednra endothelin receptor type A ISO associated with Bladder Neoplasms RGD PMID:21183790 RGD:4892282 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Eef1b2 eukaryotic translation elongation factor 1 beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 PMID:20562527 NCBI chr 9:64,580,163...64,582,737
Ensembl chr 9:64,579,893...64,582,737
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20562527 NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
JBrowse link
G Efnb2 ephrin B2 ISO associated with cholangiocarcinoma;protein:increased expression:biliary ductule (human) RGD PMID:25012246 RGD:153305948 NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391
JBrowse link
G Egf epidermal growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21942447 PMID:23064031 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfr epidermal growth factor receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:17369752 PMID:17575224 PMID:23867902 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 ISO associated with lung neoplasms;
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:20940408 PMID:25115793 PMID:20940408 RGD:9589170 NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547
JBrowse link
G Eif1ax eukaryotic translation initiation factor 1A, X-linked ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr  X:35,498,698...35,513,402
Ensembl chr  X:35,498,517...35,513,335
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781
JBrowse link
G Elp3 elongator acetyltransferase complex subunit 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27811057 NCBI chr15:39,754,635...39,816,482
Ensembl chr15:39,754,632...39,816,445
JBrowse link
G Eml4 EMAP like 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22986231 PMID:22999080 NCBI chr 6:11,219,545...11,334,824
Ensembl chr 6:11,219,566...11,334,879
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26037280 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
JBrowse link
G Epcam epithelial cell adhesion molecule IMP RGD PMID:23390083 RGD:9685143 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
JBrowse link
G Epo erythropoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16699298 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G Epor erythropoietin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16699298 NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 IMP
ISO
rat gene in a mouse model
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16984552 PMID:11238891 RGD:734938 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 disease_progression ISO associated with Prostatic Neoplasms;protein:alternative form
associated with lung adenocarcinoma
CTD Direct Evidence: marker/mechanism
associated with Prostatic Neoplasms;protein:increased expression, altered localization:bone, nucleus
CTD
RGD
PMID:28114269 PMID:18559590 PMID:26254096 PMID:17634423 RGD:2298500, RGD:126790470, RGD:2289944 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 disease_progression ISO associated with lung adenocarcinoma RGD PMID:26254096 RGD:126790470 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit disease_progression ISO associated with Melanoma
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:20801905 PMID:26202595 RGD:11252177 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:20372803 NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369
JBrowse link
G Erp29 endoplasmic reticulum protein 29 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
JBrowse link
G Esr1 estrogen receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20104649 PMID:35044086 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Etv4 ETS variant transcription factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27869830 NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO associated with stomach cancer;protein:increased expression:stomach
associated with osteosarcoma
associated with lung non-small cell carcinoma
RGD PMID:20132185 PMID:26265454 PMID:24097870 RGD:126779607, RGD:11532507, RGD:126781716 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G Ezr ezrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:27137931 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
JBrowse link
G F2 coagulation factor II, thrombin ISO associated with Carcinoma, Small cell;protein:increased expression:brain RGD PMID:22065054 RGD:6893520 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G Fadd Fas associated via death domain ISO CTD Direct Evidence: marker/mechanism CTD PMID:16450001 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Fas Fas cell surface death receptor ISO associated with Breast Neoplasms;protein:decreased expression:breast
associated with Mammary Neoplasms;protein:decreased expression:lung
RGD PMID:17352235 PMID:17918178 RGD:2290053, RGD:2290048 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand ISO associated with Breast Neoplasms;protein:decreased expression:breast RGD PMID:17352235 RGD:2290053 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fgf13 fibroblast growth factor 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19917848 NCBI chr  X:137,276,498...137,800,056
Ensembl chr  X:137,276,511...137,800,391
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 ISO associated with prostate adenocarcinoma RGD PMID:23576558 RGD:13504748 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21975929 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Fn1 fibronectin 1 treatment ISO associated with stomach cancer; human cells in mouse model RGD PMID:27431311 RGD:152995400 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fscn1 fascin actin-bundling protein 1 ISO associated with Pancreatic Neoplasms RGD PMID:15626919 RGD:2317788 NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211
JBrowse link
G Ftl1 ferritin light chain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725
JBrowse link
G Gab2 GRB2-associated binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21996746 NCBI chr 1:151,429,844...151,625,708
Ensembl chr 1:151,429,695...151,625,031
JBrowse link
G Gdf15 growth differentiation factor 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23996089 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gjb1 gap junction protein, beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17978847 NCBI chr  X:66,501,848...66,509,783
Ensembl chr  X:66,501,820...66,509,925
JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha ISO associated with Melanoma, Experimental RGD PMID:19727118 RGD:10450866 NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774
JBrowse link
G Gpcpd1 glycerophosphocholine phosphodiesterase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25482527 NCBI chr 3:119,787,681...119,832,550
Ensembl chr 3:119,787,682...119,832,517
JBrowse link
G Gpi glucose-6-phosphate isomerase ISO RGD PMID:20978190 RGD:11051956 NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086
JBrowse link
G Gpx2 glutathione peroxidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23867582 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Habp2 hyaluronan binding protein 2 treatment IMP associated with Thyroid Neoplasms RGD PMID:22715430 RGD:11353856 NCBI chr 1:255,315,870...255,350,161
Ensembl chr 1:255,315,915...255,350,160
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 disease_progression ISO DNA:polymorphisms: : +4259T>G (human) RGD PMID:22472081 RGD:7245505 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137
JBrowse link
G Hdac3 histone deacetylase 3 ISO associated with Anaphylaxis;
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:34973135 PMID:24619412 RGD:9590165 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856
JBrowse link
G Hgf hepatocyte growth factor ISO associated with Pancreatic Neoplasms
CTD Direct Evidence: marker/mechanism
associated with Mammary Neoplasms, Experimental;
associated with Melanoma;
CTD
RGD
PMID:25971889 PMID:11893931 PMID:16459153 PMID:10688652 RGD:2317904, RGD:8548625, RGD:8548538 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Hpse heparanase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22240343 NCBI chr14:8,896,593...8,937,011
Ensembl chr14:8,896,593...8,937,010
JBrowse link
G Hrh2 histamine receptor H 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:6224980 NCBI chr17:10,366,004...10,407,791
Ensembl chr17:10,368,298...10,407,631
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20562527 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:26984758 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
JBrowse link
G Ibsp integrin-binding sialoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:22407340 PMID:24980816 NCBI chr14:5,439,825...5,452,570
Ensembl chr14:5,439,829...5,452,693
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO associated with Pancreatic Neoplasms;protein:increased expression:serum
associated with Melanoma, Cutaneous Malignant
RGD PMID:12923961 PMID:10465581 RGD:2325163, RGD:8547593 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Id1 inhibitor of DNA binding 1 ISO CTD Direct Evidence: therapeutic CTD PMID:24910342 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Igf1 insulin-like growth factor 1 ISO associated with Pancreatic Neoplasms
CTD Direct Evidence: marker/mechanism
associated with Uveal Melanoma;protein:increased expression:serum:
CTD
RGD
PMID:18398872 PMID:19375852 PMID:23197685 RGD:2317643, RGD:8548834 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf1r insulin-like growth factor 1 receptor ISO associated with Pancreatic Neoplasms RGD PMID:16575403 RGD:2317645 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Igf2 insulin-like growth factor 2 ISO associated with Arthritis, Experimental; protein:increased expression:lung, bone, serum: RGD PMID:21859454 RGD:5510000 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 ISO associated with colorectal cancer;DNA:polymorphisms: RGD PMID:31320627 RGD:150540328 NCBI chr14:86,255,065...86,340,839
Ensembl chr14:86,255,065...86,342,416
JBrowse link
G Il10 interleukin 10 ISO RGD PMID:16035616 RGD:1598627 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il18 interleukin 18 ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
associated with breast cancer;DNA:SNP:promoter:-137G>C (rs187238) (human)
associated with breast cancer;protein:increased expression:serum
CTD
RGD
PMID:12748951 PMID:11215816 PMID:19152241 PMID:12209760 RGD:4889862, RGD:8655899, RGD:8655866 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il2 interleukin 2 treatment ISO associated with melanoma;
associated with neuroblastoma.
CTD Direct Evidence: therapeutic
CTD
RGD
PMID:17105418 PMID:8610104 PMID:9362156 PMID:8642346 RGD:8663438, RGD:14865005, RGD:14747043 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il6 interleukin 6 treatment ISO associated with stomach cancer, human cells in mouse model
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:21937440 PMID:26101800 PMID:28186964 RGD:127229952 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Itga6 integrin subunit alpha 6 IEP RGD PMID:13130099 RGD:1302259 NCBI chr 3:56,604,512...56,689,428
Ensembl chr 3:56,617,268...56,689,428
JBrowse link
G Itgb1 integrin subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23562787 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Itgb3 integrin subunit beta 3 ISO mRNA, protein:increased expression:lung
associated with renal cell carcinoma;DNA:missense mutation:cds:p.L33P (human)
RGD PMID:21107114 PMID:16831169 RGD:5037225, RGD:6907406 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Jak2 Janus kinase 2 treatment ISO associated with stomach cancer, human cells in mouse model RGD PMID:28186964 RGD:127229952 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Jup junction plakoglobin ISO associated with Ovarian Neoplasms RGD PMID:15619205 RGD:2301746 NCBI chr10:85,300,438...85,327,378
Ensembl chr10:85,300,440...85,327,057
JBrowse link
G Kdm6a lysine demethylase 6A disease_progression ISO associated with lung adenocarcinoma;protein:increased expression:brain (human) RGD PMID:33291558 RGD:150429741 NCBI chr  X:4,337,466...4,477,100
Ensembl chr  X:4,337,750...4,477,062
JBrowse link
G Kdr kinase insert domain receptor ISO associated with Carcinoma, Renal Cell RGD PMID:17465216 RGD:2301757 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Kif2c kinesin family member 2C disease_progression ISO associated with colorectal cancer RGD PMID:18506187 RGD:27372891 NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637
JBrowse link
G Kiss1 KiSS-1 metastasis-suppressor ISO associated with Ovarian Neoplasms RGD PMID:16283480 RGD:2298668 NCBI chr13:44,775,106...44,780,707
Ensembl chr13:44,774,823...44,780,612
JBrowse link
G Kmt2b lysine methyltransferase 2B ISO associated with lung adenocarcinoma RGD PMID:33291558 RGD:150429741 NCBI chr 1:85,821,700...85,840,987
Ensembl chr 1:85,821,753...85,841,326
JBrowse link
G Kmt2d lysine methyltransferase 2D disease_progression ISO associated with colorectal cancer;DNA:mutations:: RGD PMID:27875625 RGD:155582219 NCBI chr 7:129,980,744...130,022,088
Ensembl chr 7:129,962,887...130,020,325
JBrowse link
G Kras KRAS proto-oncogene, GTPase treatment
disease_progression
ISO CTD Direct Evidence: marker/mechanism
associated with stomach cancer; human cells in mouse model
associated with colorectal cancer; DNA:mutation:cds:
associated with colorectal cancer;DNA:mutations: :
associated with colorectal cancer;DNA:mutation: :
associated with Fibrosarcoma;mRNA,protein:decreased expression::
CTD
RGD
PMID:8635384 PMID:27431311 PMID:27264476 PMID:26210240 PMID:29032374 More... RGD:152995400, RGD:14398751, RGD:11086960, RGD:14398745, RGD:11570402 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Krt14 keratin 14 IEP mRNA:decreased expression:epithelial cell RGD PMID:9876218 RGD:1600180 NCBI chr10:85,137,786...85,142,054
Ensembl chr10:85,066,802...85,171,799
JBrowse link
G Krt20 keratin 20 ISO associated with Colorectal Neoplasms RGD PMID:10931219 RGD:2317676 NCBI chr10:84,384,790...84,394,125
Ensembl chr10:84,384,802...84,394,107
JBrowse link
G L1cam L1 cell adhesion molecule treatment ISO associated with Pancreatic Neoplasms;
associated with Lung Neoplasms;
RGD PMID:22095073 PMID:22307136 RGD:11570404, RGD:11570503 NCBI chr  X:151,597,270...151,623,776
Ensembl chr  X:151,597,277...151,623,857
JBrowse link
G Lamc2 laminin subunit gamma 2 ISO associated with lung adenocarcinoma; RGD PMID:25591736 RGD:11075980 NCBI chr13:65,284,664...65,344,164
Ensembl chr13:65,284,664...65,344,200
JBrowse link
G Lcn2 lipocalin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24570342 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Lect2 leukocyte cell-derived chemotaxin 2 ISO CTD Direct Evidence: therapeutic CTD PMID:30453282 NCBI chr17:8,044,759...8,050,983
Ensembl chr17:8,044,759...8,050,983
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 ISO associated with prostate cancer
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:27811057 PMID:27067790 RGD:11531513 NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794
JBrowse link
G Lgals3 galectin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25882088 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
JBrowse link
G Llgl2 LLGL scribble cell polarity complex component 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28114269 NCBI chr10:101,050,978...101,086,527
Ensembl chr10:101,051,408...101,086,525
JBrowse link
G Ly96 lymphocyte antigen 96 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22180778 NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386
JBrowse link
G Macc1 MET transcriptional regulator MACC1 treatment ISO associated with stomach cancer; human cells in mouse model
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:36008464 PMID:27431311 RGD:152995400 NCBI chr 6:140,352,690...140,430,255
Ensembl chr 6:140,352,755...140,430,255
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 disease_progression ISO associated with oral squamous cell carcinoma;mRNA, protein:increased expression:lymph node (human) RGD PMID:22165133 RGD:150429749 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
JBrowse link
G Mapk1 mitogen activated protein kinase 1 treatment ISO CTD Direct Evidence: marker/mechanism
associated with prostate adenocarcinoma
CTD
RGD
PMID:22580338 PMID:22139534 RGD:13504820 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22580338 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 ISO CTD Direct Evidence: therapeutic
associated with Colorectal Neoplasms
CTD
RGD
PMID:21779479 PMID:25205654 RGD:13217416 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Med28 mediator complex subunit 28 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21942447 NCBI chr14:65,594,785...65,603,583
Ensembl chr14:65,594,647...65,603,583
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase disease_progression ISO associated with Squamous Cell Carcinoma of the Tongue;
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:20080979 PMID:21225626 PMID:22704061 RGD:8548616 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
JBrowse link
G Mir100 microRNA 100 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr 8:41,901,225...41,901,304
Ensembl chr 8:41,901,225...41,901,304
JBrowse link
G Mir106a microRNA 106a ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr  X:132,422,584...132,422,661
Ensembl chr  X:132,422,584...132,422,661
JBrowse link
G Mir125a microRNA 125a ISO CTD Direct Evidence: marker/mechanism
associated with stomach cancer;
CTD
RGD
PMID:19487542 PMID:30117667 RGD:21403678 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710
JBrowse link
G Mir130a microRNA 130a ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr 3:69,822,542...69,822,629
Ensembl chr 3:69,822,542...69,822,629
JBrowse link
G Mir130b microRNA 130b ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr11:83,880,163...83,880,244
Ensembl chr11:83,880,163...83,880,244
JBrowse link
G Mir136 microRNA 136 ameliorates ISO associated with stomach cancer;human cells in mouse model RGD PMID:28656883 RGD:153344628 NCBI chr 6:128,549,096...128,549,177
Ensembl chr 6:128,549,096...128,549,177
JBrowse link
G Mir148b microRNA 148b ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr 7:134,421,398...134,421,494
Ensembl chr 7:134,421,398...134,421,494
JBrowse link
G Mir152 microRNA 152 ISO associated with Castration-Resistant Prostatic Neoplasms RGD PMID:23574937 RGD:19165145 NCBI chr10:81,832,936...81,833,020
Ensembl chr10:81,832,936...81,833,020
JBrowse link
G Mir155 microRNA 155 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19487542 PMID:27692344 PMID:27856635 RGD:21079446 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mir181c microRNA 181c ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr19:23,983,523...23,983,628
Ensembl chr19:23,983,523...23,983,628
JBrowse link
G Mir181d microRNA 181d ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr19:23,983,706...23,983,788
Ensembl chr19:23,983,706...23,983,788
JBrowse link
G Mir193a microRNA 193a exacerbates ISO associated with lung non-small cell carcinoma; human cells in mouse model RGD PMID:24469061 PMID:30685413 RGD:153344592, RGD:153344599 NCBI chr10:64,672,343...64,672,454
Ensembl chr10:64,672,343...64,672,454
JBrowse link
G Mir19a microRNA 19a ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993
JBrowse link
G Mir205 microRNA 205 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr13:105,035,878...105,035,985
Ensembl chr13:105,035,878...105,035,985
JBrowse link
G Mir20a microRNA 20a ISO associated with colorectal cancer RGD PMID:27286257 RGD:25823157 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168
JBrowse link
G Mir20b microRNA 20b ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr  X:132,422,211...132,422,282
Ensembl chr  X:132,422,211...132,422,282
JBrowse link
G Mir21 microRNA 21 treatment
ameliorates
ISO associated with prostate carcinoma; human cells in mouse model
CTD Direct Evidence: marker/mechanism
human cells in mouse model;associated with breast cancer
CTD
RGD
PMID:26101800 PMID:32736696 PMID:18270520 RGD:152998873, RGD:152998897 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mir221 microRNA 221 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573
JBrowse link
G Mir222 microRNA 222 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr  X:3,428,904...3,429,006
Ensembl chr  X:3,428,904...3,429,006
JBrowse link
G Mir224 microRNA 224 ISO CTD Direct Evidence: marker/mechanism
associated with colorectal cancer; mRNA:increased expression:colorectal mucosa:
CTD
RGD
PMID:19487542 PMID:25919696 RGD:14398749 NCBI chr  X:150,065,088...150,065,169
Ensembl chr  X:150,065,088...150,065,169
JBrowse link
G Mir30a microRNA 30a ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670
JBrowse link
G Mir30e microRNA 30e ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr 5:134,352,232...134,352,323
Ensembl chr 5:134,352,232...134,352,323
JBrowse link
G Mir31 microRNA 31 disease_progression
treatment
ISO CTD Direct Evidence: marker/mechanism
associated with colorectal cancer;RNA:increased expression:colorectum (human)
associated with stomach cancer;human cells in mouse model
CTD
RGD
PMID:19487542 PMID:26497852 PMID:27174918 PMID:30108104 RGD:153297806, RGD:153297811, RGD:153297776 NCBI chr 5:103,599,038...103,599,143 JBrowse link
G Mir342 microRNA 342 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr 6:127,565,269...127,565,367
Ensembl chr 6:127,565,269...127,565,367
JBrowse link
G Mir346 microRNA 346 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27501413 PMID:27777383 NCBI chr16:10,218,118...10,218,215
Ensembl chr16:10,218,118...10,218,215
JBrowse link
G Mir34b microRNA 34b ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr 8:51,410,244...51,410,327
Ensembl chr 8:51,410,244...51,410,327
JBrowse link
G Mir34c microRNA 34c ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr 8:51,409,726...51,409,802
Ensembl chr 8:51,409,726...51,409,802
JBrowse link
G Mir370 microRNA 370 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr 6:128,572,257...128,572,335
Ensembl chr 6:128,572,257...128,572,335
JBrowse link
G Mir494 microRNA 494 ISO associated with osteosarcoma; RNA:decreased expression:bone, serum RGD PMID:30314946 PMID:35117781 RGD:156420141, RGD:156430319 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793
JBrowse link
G Mir503 microRNA 503 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr  X:132,806,303...132,806,373
Ensembl chr  X:132,806,303...132,806,373
JBrowse link
G Mir532 microRNA 532 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr  X:15,247,315...15,247,393
Ensembl chr  X:15,247,315...15,247,393
JBrowse link
G Mir96 microRNA 96 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516
JBrowse link
G Mir99a microRNA 99a ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr11:16,200,443...16,200,523
Ensembl chr11:16,200,443...16,200,523
JBrowse link
G Mir99b microRNA 99b ISO CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr 1:58,677,015...58,677,084
Ensembl chr 1:58,677,011...58,677,090
JBrowse link
G Mki67 marker of proliferation Ki-67 ISO associated with Pancreatic Neoplasms RGD PMID:20388395 RGD:2317702 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mlh1 mutL homolog 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17717427 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12538496 PMID:19487542 PMID:22580338 PMID:23548910 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp10 matrix metallopeptidase 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22022614 NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748
JBrowse link
G Mmp13 matrix metallopeptidase 13 ISO associated with Carcinoma, Renal Cell;mRNA, protein:increased expression:bone RGD PMID:18709334 RGD:2306080 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link
G Mmp2 matrix metallopeptidase 2 disease_progression ISO
IEP
associated with Gallbladder Neoplasms; protein:increased expression:gallbladder
associated with pancreatic cancer; protein:increased expression, increased activity:pancreas
CTD Direct Evidence: marker/mechanism
associated with Mammary Neoplasms, Animal;protein:increased expression:brain
RGD
CTD
PMID:12173379 PMID:16475674 PMID:18398872 PMID:21209944 PMID:22321834 More... RGD:2325749, RGD:2325743, RGD:8547884, RGD:2325749 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp24 matrix metallopeptidase 24 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27869830 NCBI chr 3:144,279,096...144,323,572
Ensembl chr 3:144,279,096...144,323,572
JBrowse link
G Mmp3 matrix metallopeptidase 3 IEP associated with Mammary Neoplasms, Animal;protein:increased expression:brain RGD PMID:16158251 RGD:8547884 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mmp9 matrix metallopeptidase 9 severity
disease_progression
ISO
IMP
IEP
associated with pancreatic cancer; protein:increased expression, increased activity:pancreas
CTD Direct Evidence: marker/mechanism
associated with osteosarcoma;protein:increased expression:bone (human)
associated with skin melanoma;DNA:missense mutation:cds:p.Q279R (human)
associated with Mammary Neoplasms, Animal;protein:increased expression:brain
associated with Melanoma
associated with Mammary Neoplasms, Animal; associated with Arthritis, Experimental
associated with carcinoma, pancreatic ductal; protein:increased expression:pancreas
CTD
RGD
PMID:15659795 PMID:16475674 PMID:18930813 PMID:21209944 PMID:21942447 More... RGD:152023746, RGD:2325749, RGD:8547928, RGD:8547886, RGD:8547884, RGD:8547878, RGD:8547861, RGD:5510000, RGD:2325855 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Msh2 mutS homolog 2 ISO associated with Breast Neoplasms RGD PMID:17390069 RGD:2293506 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Mst1 macrophage stimulating 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28114269 NCBI chr 8:108,767,886...108,773,425
Ensembl chr 8:108,768,839...108,773,416
JBrowse link
G Mtdh metadherin ISO CTD Direct Evidence: therapeutic CTD PMID:19111877 NCBI chr 7:65,306,464...65,365,647
Ensembl chr 7:65,306,400...65,364,413
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17704422 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Mtor mechanistic target of rapamycin kinase IMP associated with Pancreatic Neoplasms RGD PMID:23149918 RGD:10040959 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Muc1 mucin 1, cell surface associated disease_progression ISO associated with Pancreatic Neoplasms
associated with Carcinoma, Renal Cell;
RGD PMID:16707592 PMID:10390012 PMID:12941828 RGD:2324648, RGD:7245968, RGD:2324652 NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Muc4 mucin 4, cell surface associated IMP associated with Melanoma RGD PMID:10918186 RGD:2303746 NCBI chr11:68,008,245...68,053,242 JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming ISO associated with chloangiocarcinoma;protein:increased expression:bile duct RGD PMID:16124042 RGD:2324987 NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475
JBrowse link
G Muc6 mucin 6, oligomeric mucus/gel-forming disease_progression ISO associated with cholangiocarcinoma RGD PMID:18410610 RGD:2325159 NCBI chr 1:196,726,678...196,764,842
Ensembl chr 1:196,726,807...196,764,842
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22321834 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Mylk myosin light chain kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12970723 PMID:18710790 NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261
JBrowse link
G Nagk N-acetylglucosamine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr 4:116,281,179...116,293,870
Ensembl chr 4:116,281,328...116,313,137
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21080969 NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664
JBrowse link
G Ndc80 NDC80 kinetochore complex component disease_progression ISO associated with melanoma RGD PMID:31173190 RGD:40822820 NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924
JBrowse link
G Ndrg1 N-myc downstream regulated 1 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:15867226 PMID:22972152 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Nectin2 nectin cell adhesion molecule 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29321541 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32682831 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 ISO associated with prostate cancer RGD PMID:17974971 RGD:13506764 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha ISO associated with prostate cancer;protein:increased serine phosphorylation RGD PMID:23093296 RGD:13506767 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 ISO associated with Ovarian Neoplasms
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:15928304 PMID:7622307 RGD:2299069 NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 resistance IMP RGD PMID:8621239 RGD:2299081 NCBI chr10:78,898,097...78,903,514
Ensembl chr10:78,897,770...78,903,538
JBrowse link
G Nos2 nitric oxide synthase 2 disease_progression ISO associated with Gallbladder Neoplasms: protein:increased expression:gallbladder
associated with Carcinoma, Pancreatic Ductal
associated with Carcinoma, Pancreatic Ductal; protein:increased expression:pancreas
RGD PMID:14991947 PMID:12660813 PMID:15222037 RGD:2325250, RGD:2325254, RGD:2325242 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility ISO protein:increased expression:blood vessel endothelial cell
associated with Prostatic Neoplasms;DNA:polymorphism
associated with Breast Neoplasms;DNA:polymorphism:promoter:-786T>C (human)
RGD PMID:14672505 PMID:12445681 PMID:14623178 RGD:2292080, RGD:2292087, RGD:2292081 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nppa natriuretic peptide A ISO CTD Direct Evidence: therapeutic CTD PMID:18717826 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Nsun6 NOP2/Sun RNA methyltransferase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28114269 NCBI chr17:77,912,374...77,955,694
Ensembl chr17:77,912,377...77,950,006
JBrowse link
G Ogn osteoglycin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr17:15,032,069...15,052,626
Ensembl chr17:15,032,069...15,052,739
JBrowse link
G Olig2 oligodendrocyte transcription factor 2 ISO associated with breast cancer RGD PMID:27340107 RGD:40902824 NCBI chr11:30,475,510...30,478,886
Ensembl chr11:30,475,398...30,480,152
JBrowse link
G Orai1 ORAI calcium release-activated calcium modulator 1 treatment ISO associated with stomach cancer; human cells in mouse model RGD PMID:27431311 RGD:152995400 NCBI chr12:33,533,151...33,548,361
Ensembl chr12:33,534,344...33,548,405
JBrowse link
G Osm oncostatin M ISO CTD Direct Evidence: marker/mechanism CTD PMID:21937440 NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313
JBrowse link
G Pcna proliferating cell nuclear antigen ISO associated with Seminoma RGD PMID:9143022 RGD:2315011 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pde5a phosphodiesterase 5A ISO CTD Direct Evidence: marker/mechanism CTD PMID:12972520 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO associated with Breast Neoplasms;mRNA, protein:increased expression:breast RGD PMID:16596190 RGD:2292179 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta ISO associated with Carcinoma, Renal Cell
mRNA,protein:increased expression: :
RGD PMID:15994946 PMID:14593398 RGD:2292198, RGD:13703041 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 ISO associated with Prostatic Neoplasms;protein:decreased expression: RGD PMID:12813171 RGD:2302862 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
JBrowse link
G Pik3c2b phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:21986133 NCBI chr13:44,494,673...44,555,663
Ensembl chr13:44,495,050...44,555,612
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha treatment ISO CTD Direct Evidence: marker/mechanism
associated with colorectal cancer;DNA:mutations::
CTD
RGD
PMID:29106415 PMID:23302486 RGD:14402409 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 ISO associated with Adenocarcinoma, Colon RGD PMID:24837077 RGD:13432045 NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583
JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16475674 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO associated with Ovarian Neoplasms
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:15659795 PMID:22577342 RGD:6483788 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595
JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 ameliorates ISO associated with lung non-small cell carcinoma RGD PMID:29072684 RGD:151665822 NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255
JBrowse link
G Pml PML nuclear body scaffold ISO CTD Direct Evidence: marker/mechanism CTD PMID:29335545 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component ISO CTD Direct Evidence: marker/mechanism CTD PMID:17717427 NCBI chr12:10,676,818...10,701,161
Ensembl chr12:10,676,764...10,701,066
JBrowse link
G Ppia peptidylprolyl isomerase A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21956400 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
JBrowse link
G Prnp prion protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:17387271 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
JBrowse link
G Prox1 prospero homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17415710 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183
JBrowse link
G Prss8 serine protease 8 ISO associated with Prostatic Neoplasms;mRNA:decreased expression:prostate gland, bone RGD PMID:12518323 RGD:2292484 NCBI chr 1:182,536,229...182,540,745
Ensembl chr 1:182,536,229...182,540,815
JBrowse link
G Ptch1 patched 1 ISO associated with colorectal cancer RGD PMID:20230186 RGD:150523835 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333
JBrowse link
G Pten phosphatase and tensin homolog ISO associated with Mammary Neoplasms, Experimental
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:10978354 PMID:18381417 RGD:2292496 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptgis prostaglandin I2 synthase exacerbates ISO associated with colorectal cancer; protein:increased expression:colorectum (human) RGD PMID:22109564 RGD:151347833 NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP
ISO
associated with Mammary Neoplasms, Experimental
CTD Direct Evidence: marker/mechanism
associated with osteosarcoma;
associated with breast neoplasm;
associated with lung neoplasm
associated with Breast Neoplasms
CTD
RGD
PMID:16489006 PMID:18509974 PMID:18398660 PMID:18797196 PMID:19421193 More... RGD:2300249, RGD:5135500, RGD:5135498, RGD:5135282, RGD:2300119 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptk2 protein tyrosine kinase 2 ISO
IMP
associated with Mammary Neoplasms, Experimental RGD PMID:16547501 PMID:15930288 RGD:2292557, RGD:2292560 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Pxn paxillin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18492274 NCBI chr12:41,060,791...41,107,952
Ensembl chr12:41,060,791...41,107,931
JBrowse link
G Rac1 Rac family small GTPase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18506888 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Rad52 RAD52 homolog, DNA repair protein susceptibility ISO associated with colorectal cancer; DNA:SNP:3'utr: (rs7963551) (human) RGD PMID:29245274 RGD:151361161 NCBI chr 4:153,106,062...153,128,598
Ensembl chr 4:153,106,062...153,128,207
JBrowse link
G Ramp2 receptor activity modifying protein 2 ISO RGD PMID:31754214 RGD:152985691 NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829
JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27137931 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs ISO CTD Direct Evidence: marker/mechanism CTD PMID:17233834 NCBI chr 5:58,102,961...58,169,516
Ensembl chr 5:58,102,981...58,169,502
JBrowse link
G Rhoa ras homolog family member A ISO associated with Ovarian Neoplasms RGD PMID:12808121 RGD:2298873 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rhoc ras homolog family member C ISO associated with Ovarian Neoplasms
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:18230616 PMID:12808121 RGD:2298873 NCBI chr 2:192,287,065...192,293,292
Ensembl chr 2:192,287,130...192,295,306
JBrowse link
G Rit1 Ras-like without CAAX 1 ameliorates ISO associated with esophagus squamous cell carcinoma; human cells in mouse model RGD PMID:30348939 RGD:152999018 NCBI chr 2:174,180,742...174,195,455
Ensembl chr 2:174,180,848...174,195,455
JBrowse link
G Ror1 receptor tyrosine kinase-like orphan receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28114269 NCBI chr 5:114,744,311...115,088,155
Ensembl chr 5:114,744,304...115,088,155
JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21488662 NCBI chr  X:35,517,306...35,623,296
Ensembl chr  X:35,517,306...35,623,207
JBrowse link
G Rxra retinoid X receptor alpha IEP associated with Prostatic Neoplasms RGD PMID:15318950 RGD:1643115 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G S100a4 S100 calcium-binding protein A4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21636539 PMID:21685359 PMID:36008464 NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254
JBrowse link
G Serpina1 serpin family A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339
JBrowse link
G Serpinb5 serpin family B member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19514085 NCBI chr13:22,985,557...23,005,756
Ensembl chr13:22,985,557...23,005,756
JBrowse link
G Serpinc1 serpin family C member 1 treatment ISO associated with Adenocarcinoma, Colon
associated with Melanoma
RGD PMID:16440418 PMID:16440418 RGD:1599327, RGD:1599327 NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293
JBrowse link
G Serpinf1 serpin family F member 1 IEP associated with Prostatic Neoplasms RGD PMID:15313905 RGD:2312355 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
JBrowse link
G Sirt1 sirtuin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27793039 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Six1 SIX homeobox 1 ISO human gene in a mouse model RGD PMID:23435380 RGD:11561950 NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975
JBrowse link
G Slc39a4 solute carrier family 39 member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20957146 NCBI chr 7:108,333,368...108,337,553
Ensembl chr 7:108,333,381...108,337,553
JBrowse link
G Slc39a6 solute carrier family 39 member 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12839489 NCBI chr18:15,864,874...15,885,417
Ensembl chr18:15,864,875...15,885,417
JBrowse link
G Slc3a2 solute carrier family 3 member 2 ISO RGD PMID:19018776 RGD:151361278 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
JBrowse link
G Slc7a11 solute carrier family 7 member 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19015640 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Slc7a5 solute carrier family 7 member 5 ISO RGD PMID:19018776 RGD:151361278 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 IEP associated with Colonic Neoplasms;protein:decreased expression:liver RGD PMID:16895976 RGD:2302565 NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981
JBrowse link
G Smad4 SMAD family member 4 disease_progression ISO associated with colorectal carcinoma;DNA:mutation:cds: RGD PMID:10340381 RGD:21066333 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Smo smoothened, frizzled class receptor ISO associated with colon cancer RGD PMID:23098507 RGD:150340555 NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829
JBrowse link
G Snai1 snail family transcriptional repressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22580338 PMID:23219715 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Snai2 snail family transcriptional repressor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22580338 NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Sncg synuclein, gamma ISO protein:increased expression:breast
DNA:hypomethylation: :
RGD PMID:16821081 PMID:16140929 RGD:6478795, RGD:6478797 NCBI chr16:9,700,513...9,705,751
Ensembl chr16:9,700,514...9,705,368
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12538496 PMID:18930813 PMID:19487542 PMID:22580338 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sox30 SRY-box transcription factor 30 ISO associated with lung non-small cell carcinoma;mRNA, protein:decreased expression: : RGD PMID:29739711 RGD:151660333 NCBI chr10:30,417,499...30,446,441
Ensembl chr10:30,418,473...30,446,453
JBrowse link
G Sox9 SRY-box transcription factor 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32682831 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
G Sp1 Sp1 transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12538496 PMID:35072892 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
JBrowse link
G Spa17 sperm autoantigenic protein 17 ISO associated with ovarian carcinoma;proetin:increased expression:epithelium: RGD PMID:19744347 RGD:27226802 NCBI chr 8:37,307,432...37,318,519
Ensembl chr 8:37,307,557...37,318,639
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:22407340 PMID:16474180 RGD:1581330 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO associated with colorectal carcinoma;protein:increased activity:colorectum: RGD PMID:15486073 PMID:7687314 RGD:1581401, RGD:150521537 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30394316 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr10:72,838,926...72,859,066
Ensembl chr10:72,839,274...72,845,336
JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 severity ISO associated with hepatocellular carcinoma RGD PMID:29278882 RGD:150429692 NCBI chr10:102,052,158...102,055,365
Ensembl chr10:102,052,314...102,055,338
JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 ISO associated with Ovarian Neoplasms;mRNA:increased expression:epithelium of female gonad (human) RGD PMID:23748175 RGD:11039469 NCBI chr 6:100,605,165...100,610,192
Ensembl chr 6:100,605,456...100,610,177
JBrowse link
G Srsf6 serine and arginine rich splicing factor 6 ISO associated with Ovarian Neoplasms;mRNA:increased expression:epithelium of female gonad (human) RGD PMID:23748175 RGD:11039469 NCBI chr 3:151,589,546...151,594,869
Ensembl chr 3:151,589,535...151,594,860
JBrowse link
G St14 ST14 transmembrane serine protease matriptase ISO associated with Prostatic Neoplasms
associated with Breast Neoplasms
RGD PMID:18813126 PMID:17456594 RGD:2315088, RGD:2315092 NCBI chr 8:29,540,805...29,581,704
Ensembl chr 8:29,540,811...29,581,517
JBrowse link
G Stat1 signal transducer and activator of transcription 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29147627 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Stat3 signal transducer and activator of transcription 3 treatment ISO associated with Carcinoma, Renal Cell;protein:increased phosphorylation
CTD Direct Evidence: marker/mechanism
associated with Melanoma
associated with Prostatic Neoplasms;protein:decreased activity
CTD
RGD
PMID:21937440 PMID:23382965 PMID:26101800 PMID:12131365 PMID:16540670 More... RGD:2291917, RGD:8694303, RGD:2291915 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stat5a signal transducer and activator of transcription 5A disease_progression ISO DNA:CNV: :prostate (human) RGD PMID:23660011 RGD:151667415 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
JBrowse link
G Stim1 stromal interaction molecule 1 ameliorates
treatment
exacerbates
ISO human cells in mouse model;associated with lung cancer
associated with stomach cancer; human cells in mouse model
associated with hepatocellular carcinoma;protein:decreased expression:liver (human)
associated with nasopharynx carcinoma; human cells in mouse model
RGD PMID:28713917 PMID:27431311 PMID:32483465 PMID:32165272 RGD:152995357, RGD:152995400, RGD:152995387, RGD:152995361 NCBI chr 1:156,656,246...156,818,777
Ensembl chr 1:156,656,013...156,818,363
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 IEP associated with Colonic Neoplasms;protein:increased expression:liver RGD PMID:16895976 RGD:2302565 NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275
JBrowse link
G Tbcb tubulin folding cofactor B ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr 1:85,477,639...85,483,488
Ensembl chr 1:85,477,640...85,483,488
JBrowse link
G Tcf3 transcription factor 3 disease_progression ISO associated with colon cancer RGD PMID:26212009 RGD:11533019 NCBI chr 7:9,280,571...9,302,315
Ensembl chr 7:9,280,571...9,302,314
JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 ISO associated with colorectal cancer; protein:decreased expression:colorectum (human) RGD PMID:33552282 RGD:150429609 NCBI chr 2:221,988,645...222,072,813
Ensembl chr 2:221,988,645...222,072,534
JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 disease_progression ISO CTD Direct Evidence: marker/mechanism
associated with stomach carcinoma;DNA:hypermethylation
CTD
RGD
PMID:17372906 PMID:25009298 RGD:150527841 NCBI chr 4:31,981,786...31,986,707
Ensembl chr 4:31,982,178...31,986,600
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23146760 PMID:23992306 PMID:26896736 PMID:31381904 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 ISO associated with Mammary Neoplasms, Experimental RGD PMID:12808151 RGD:737735 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 ISO associated with Mammary Neoplasms, Experimental
CTD Direct Evidence: therapeutic
CTD
RGD
PMID:16489006 PMID:12808151 RGD:737735 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 ISO CTD Direct Evidence: therapeutic CTD PMID:29746904 NCBI chr 9:110,748,094...110,757,714
Ensembl chr 9:110,720,921...110,757,802
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 ISO associated with Breast Neoplasms;protein:increased expression:plasma RGD PMID:17407159 RGD:2290346 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 ISO associated with Breast Neoplasms RGD PMID:17505812 RGD:2290394 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
JBrowse link
G Tlr4 toll-like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22180778 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnc tenascin C ISO associated with Carcinoma, Renal Cell;protein:increased expression:lung RGD PMID:16928692 RGD:4889612 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:8032535 PMID:23431386 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip8 TNF alpha induced protein 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21969086 NCBI chr18:43,183,854...43,299,512
Ensembl chr18:43,183,916...43,299,517
JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A ISO associated with Prostatic Neoplasms;protein:increased expression:bone, lymph node RGD PMID:16752412 RGD:2302322 NCBI chr13:21,928,370...21,986,719
Ensembl chr13:21,928,408...21,986,695
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B ISO associated with Breast Neoplasms;protein:increased expression:serum RGD PMID:23167338 RGD:7205479 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
JBrowse link
G Tnfsf10 TNF superfamily member 10 ISO CTD Direct Evidence: therapeutic CTD PMID:21209944 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tp53 tumor protein p53 ISO
IMP
CTD Direct Evidence: marker/mechanism
associated with Sarcoma;
CTD
RGD
PMID:17949449 PMID:22009531 PMID:23873029 PMID:27137931 PMID:15118671 More... RGD:1331525, RGD:11075090 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp63 tumor protein p63 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15875781 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
JBrowse link
G Tpm4 tropomyosin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr16:17,684,415...17,698,456
Ensembl chr16:17,683,195...17,705,984
JBrowse link
G Ttr transthyretin treatment ISO associated with colorectal adenocarcinoma;protein:decreased expression:colorectum (human)
associated with colorectal cancer
associated with oral squamous cell carcinoma;protein:decreased expression:blood serum, saliva (human)
RGD PMID:33739034 PMID:28730771 PMID:20957082 RGD:151660505, RGD:151665163, RGD:151665158 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
JBrowse link
G Twist1 twist family bHLH transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19806464 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653
JBrowse link
G Txn1 thioredoxin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30396169 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
G Txndc5 thioredoxin domain containing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr17:26,289,880...26,318,025
Ensembl chr17:26,289,880...26,318,025
JBrowse link
G Tymp thymidine phosphorylase ISO associated with Breast Neoplasms
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:11103787 PMID:18441329 RGD:2293714 NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874
Ensembl chr 7:120,438,770...120,443,874
JBrowse link
G Tyms thymidylate synthetase disease_progression ISO associated with Gastrointestinal Neoplasms;DNA:SNPs: : RGD PMID:25677447 RGD:11081002 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
JBrowse link
G Tyr tyrosinase no_association ISO associated with melanoma; RGD PMID:11092039 RGD:8694395 NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207
JBrowse link
G Uchl3 ubiquitin C-terminal hydrolase L3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr15:78,485,304...78,527,355
Ensembl chr15:78,485,315...78,527,355
Ensembl chr 3:78,485,315...78,527,355
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO associated with Pancreatic Neoplasms;protein:increased expression:serum RGD PMID:12923961 RGD:2325163 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vdr vitamin D receptor ISO associated with breast cancer;DNA:SNP:intron: (rs1544410) (human) RGD PMID:9613456 RGD:8158057 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link
G Vegfa vascular endothelial growth factor A ISO associated with Carcinoma, Renal Cell
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:15659795 PMID:18930813 PMID:20158913 PMID:19064974 RGD:2315468 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vim vimentin treatment ISO CTD Direct Evidence: marker/mechanism
associated with stomach cancer; human cells in mouse model
CTD
RGD
PMID:17085005 PMID:27431311 RGD:152995400 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Vip vasoactive intestinal peptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:19189304 NCBI chr 1:42,064,878...42,073,219
Ensembl chr 1:42,065,120...42,073,216
JBrowse link
G Wfdc18 WAP four-disulfide core domain 18 IEP associated with Mammary Neoplasms, Experimental;mRNA:increased expression RGD PMID:3136918 RGD:632771 NCBI chr10:68,588,818...68,590,972
Ensembl chr10:68,588,818...68,589,671
JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27777383 NCBI chr 4:123,993,670...124,020,922
Ensembl chr 4:123,993,666...124,021,010
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 susceptibility ISO associated with Neoplasms, Germ Cell and Embryonal;DNA:polymorphism: :p.R399Q RGD PMID:16596238 RGD:2302576 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701
JBrowse link
G Yap1 Yes1 associated transcriptional regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:28114269 NCBI chr 8:5,095,705...5,166,808
Ensembl chr 8:5,095,722...5,167,010
JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:17085005 NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589
JBrowse link
G Zfhx3 zinc finger homeobox 3 exacerbates ISO brain metastasis associated with lung adenocarcinoma;DNA:mutations:multiple (human) RGD PMID:33479213 RGD:151361170 NCBI chr19:36,257,196...36,886,104
Ensembl chr19:36,630,254...36,881,771
JBrowse link
G Zfp382 zinc finger protein 382 disease_progression ISO associated with stomach carcinoma;DNA:hypermethylation RGD PMID:25009298 RGD:150527841 NCBI chr 1:85,377,614...85,400,832
Ensembl chr 1:85,377,484...85,399,667
JBrowse link
Bone Metastasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12 arachidonate 12-lipoxygenase, 12S type ISO associated with Prostatic Neoplasms; RGD PMID:14669797 RGD:1578303 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542
JBrowse link
G Brip1 BRCA1 interacting helicase 1 ISO associated with Breast Neoplasms; human gene in a mouse model RGD PMID:22875853 RGD:11252149 NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 disease_progression ISO associated with hepatocellular carcinoma;protein:increased expression:liver (human) RGD PMID:19508713 RGD:152023653 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISO associated with Breast Neoplasms;mRNA:increased expression:bone element (human) RGD PMID:23861746 RGD:13204736 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715
JBrowse link
G Mir34a microRNA 34a susceptibility ISO associated with hepatocellular carcinoma;miRNA:decreased expression:serum, bone RGD PMID:27893432 RGD:14694837 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103
JBrowse link
G Mmp13 matrix metallopeptidase 13 ISO associated with Carcinoma, Renal Cell; mRNA, protein:increased expression:bone (human) RGD PMID:18709334 RGD:2306080 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link
G Pdgfd platelet derived growth factor D ISO associated with prostate carcinoma RGD PMID:22158043 RGD:13506772 NCBI chr 8:3,488,448...3,722,395
Ensembl chr 8:3,488,423...3,722,395
JBrowse link
Circulating Neoplastic Cells term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29044505 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
Liver Metastasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO associated with colorectal cancer;mRNA:increased expression:liver (mouse) RGD PMID:20380732 RGD:25671446 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase severity IAGP associated with colorectal cancer;DNA:mutation:cds:
associated with colorectal cancer;DNA:mutations:multiple
associated with skin melanoma;DNA:missense mutations:cds:
associated with colorectal cancer;DNA:missense mutations:cds:pV599E,p.V600E (human)
associated with colorectal cancer;DNA:missense mutation:cds:p.V600E (human)
RGD PMID:27737491 PMID:26775732 PMID:28787433 PMID:22331825 PMID:23010994 RGD:18337264, RGD:11554843, RGD:14696791, RGD:18337265, RGD:15039394 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 disease_progression ISO associated with colorectal cancer RGD PMID:27058904 RGD:14995463 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 treatment ISO associated with Animal Mammary Neoplasms; RGD PMID:15692764 RGD:14995455 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccnd2 cyclin D2 ISO associated with colorectal cancer;protein:increased expression:colorectum RGD PMID:19508551 RGD:151665111 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccng1 cyclin G1 treatment ISO human cells in mouse model RGD PMID:10910035 RGD:151356987 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Cd44 CD44 molecule ISO associated with Breast Neoplasm;protein:increased expression:liver RGD PMID:17991717 RGD:2289349 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 ameliorates ISO associated with human colon adenocarcinoma cells in a mouse model RGD PMID:28486105 RGD:153323299 NCBI chr 4:157,898,503...157,931,632
Ensembl chr 4:157,899,391...157,931,541
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 treatment ISO associated with colon carcinoma; RGD PMID:30381616 RGD:27095891 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 ameliorates ISO associated with colorectal cancer; human cells in mouse model RGD PMID:30789971 RGD:151893289 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ameliorates ISO associated with colorectal cancer; human cells in mouse model
human cells in mouse model; associated with colorectal cancer
RGD PMID:30789971 PMID:29436696 RGD:151893289, RGD:152023643 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Daxx death-domain associated protein exacerbates ISO associated with colon cancer; mRNA:decreased expression:liver (human)
associated with pancreatic endocrine carcinoma;DNA:mutations:CDS:multiple (human)
associated with neuroendocrine tumor;DNA:mutations:CDS:multiple (human)
RGD PMID:31942198 PMID:30339629 PMID:30342802 RGD:152025194, RGD:152025203, RGD:152025199 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 treatment ISO mRNA:increased expression:liver (mouse)
human cells in mouse model; nilotinib
RGD PMID:33110221 PMID:30666650 PMID:29438985 RGD:151347537, RGD:151347840, RGD:151347685 NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 ameliorates ISO associated with colon carcinoma
associated with melanoma;
RGD PMID:22071959 PMID:21701781 RGD:150429701, RGD:150429713 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363
JBrowse link
G Dock6 dedicator of cytokinesis 6 ameliorates ISO associated with stomach cancer; RGD PMID:29587866 RGD:155791564 NCBI chr 8:20,342,430...20,394,660
Ensembl chr 8:20,342,089...20,394,552
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 disease_progression ISO associated with colorectal cancer; RGD PMID:28846828 RGD:21408566 NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 ISO associated with colorectal cancer;mRNA:increased expression:colorectal mucosa: RGD PMID:19082464 RGD:25330357 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit ISO human cells in mouse model RGD PMID:30114390 RGD:153344554 NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034
JBrowse link
G Gpc3 glypican 3 ISO protein:increased expression:blood serum (human) RGD PMID:28801286 RGD:243065135 NCBI chr  X:131,868,986...132,236,824
Ensembl chr  X:131,868,990...132,236,798
JBrowse link
G Hmbs hydroxymethylbilane synthase IEP associated with colon adenocarcinoma;protein:decreased activity:liver(rat) RGD PMID:1386052 RGD:25440496 NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957
JBrowse link
G Il2 interleukin 2 treatment ISO associated with Colorectal Neoplasms, Carcinoma, Hepatocellular;
associated with colon carcinoma
RGD PMID:11591892 PMID:9354462 RGD:8663446, RGD:14928215 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Iqsec1 IQ motif and Sec7 domain ArfGEF 1 ISO human cells in mouse model RGD PMID:22662237 RGD:153344589 NCBI chr 4:123,168,719...123,488,300
Ensembl chr 4:123,168,719...123,488,172
JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 ISO associated with colon cancer;protein:increased expression:colon (human) RGD PMID:24533778 RGD:155259116 NCBI chr12:2,591,312...2,600,534
Ensembl chr12:2,591,219...2,604,222
JBrowse link
G Mir141 microRNA 141 ISO associated with colorectal cancer;RNA:increased expression:liver: RGD PMID:28617555 RGD:14928321 NCBI chr 4:157,523,239...157,523,332
Ensembl chr 4:157,523,239...157,523,332
JBrowse link
G Mir148b microRNA 148b exacerbates ISO associated with stomach cancer; RGD PMID:29587866 RGD:155791564 NCBI chr 7:134,421,398...134,421,494
Ensembl chr 7:134,421,398...134,421,494
JBrowse link
G Mir155 microRNA 155 ISO RGD PMID:26885061 RGD:21079444 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mir200b microRNA 200b ISO associated with colorectal cancer;RNA:increased expression:liver: RGD PMID:28617555 RGD:14928321 NCBI chr 5:166,649,272...166,649,366
Ensembl chr 5:166,649,272...166,649,366
JBrowse link
G Mir200c microRNA 200c ISO associated with colorectal cancer;RNA:increased expression:liver: RGD PMID:28617555 RGD:14928321 NCBI chr 4:157,523,679...157,523,747 JBrowse link
G Mir223 microRNA 223 disease_progression ISO associated with colorectal cancer; RGD PMID:28846828 RGD:21408566 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996
JBrowse link
G Mir494 microRNA 494 exacerbates ISO associated with pancreatic ductal adenocarcinoma; RGD PMID:24859161 RGD:156430321 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793
JBrowse link
G Mpl MPL proto-oncogene, thrombopoietin receptor severity
exacerbates
ISO associated with pancreatic ductal adenocarcinoma; human cells in mouse model
associated with colorectal carcinoma;protein:increased expression:colorectum (human)
associated with pancreatic cancer; protein:increased expression:liver, pancreas (human)
RGD PMID:30770989 PMID:23747337 PMID:30770989 RGD:126925751, RGD:126925752, RGD:126925751 NCBI chr 5:131,973,895...131,987,472
Ensembl chr 5:131,973,895...131,986,797
JBrowse link
G Nras NRAS proto-oncogene, GTPase susceptibility ISO human gene in a mouse model;DNA:missense mutations:cds:p.G12V, p.Q61K (human)
associated with colorectal cancer;DNA:mutations:exons (human)
associated with melanoma;DNA:mutations: exons (human)
RGD PMID:26799184 PMID:28011498 PMID:28787433 RGD:14696774, RGD:14696792, RGD:14696791 NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626
JBrowse link
G Ptprb protein tyrosine phosphatase, receptor type, B treatment ISO mouse tumor cells in mouse recipient RGD PMID:31348125 RGD:151660353 NCBI chr 7:51,953,375...52,034,751
Ensembl chr 7:51,930,015...52,034,748
JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 disease_progression ISO mRNA:increased expression:liver (human) RGD PMID:30404068 PMID:30404068 RGD:152995463, RGD:152995463 NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426
JBrowse link
G Rnf43 ring finger protein 43 ISO associated with colorectal adenocarcinoma;mRNA:increased expression:liver (human) RGD PMID:28789449 RGD:151361221 NCBI chr10:72,461,508...72,537,301
Ensembl chr10:72,464,348...72,536,977
JBrowse link
G Slc3a2 solute carrier family 3 member 2 severity IEP associated with colon adenocarcinoma RGD PMID:11745822 RGD:151361130 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
JBrowse link
G Slc7a5 solute carrier family 7 member 5 severity IEP associated with colon cancer
associated with colon adenocarcinoma
RGD PMID:11718450 PMID:11745822 RGD:151361129, RGD:151361130 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
JBrowse link
G Smad4 SMAD family member 4 treatment ISO associated with colorectal carcinoma; DNA:mutations: :
associated with colorectal carcinoma;protein:decreased expression:colorectum:
RGD PMID:29551247 PMID:17390050 RGD:18937000, RGD:21066338 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Sox30 SRY-box transcription factor 30 ameliorates ISO RGD PMID:29739711 RGD:151660333 NCBI chr10:30,417,499...30,446,441
Ensembl chr10:30,418,473...30,446,453
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase disease_progression ISO associated with colon cancer;protein:increased activity:colon RGD PMID:7678609 RGD:150521542 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Vegfa vascular endothelial growth factor A ISO associated with colorectal carcinoma;mRNA,protein:increased expression:liver: RGD PMID:22156924 RGD:15014782 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
lung metastasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam28 ADAM metallopeptidase domain 28 ameliorates ISO associated with lung carcinoma, breast carcinoma
associated with lung adenocarcinoma;
RGD PMID:22636800 PMID:26800504 RGD:153297785, RGD:11531771 NCBI chr15:43,774,463...43,840,726
Ensembl chr15:42,944,467...43,840,672
JBrowse link
G Arhgap5 Rho GTPase activating protein 5 ISO associated with Mammary Neoplasms, Experimental RGD PMID:20860838 RGD:126848767 NCBI chr 6:69,975,904...70,039,299
Ensembl chr 6:69,976,214...70,037,660
JBrowse link
G Arid2 AT-rich interaction domain 2 exacerbates ISO associated with hepatocellular carcinoma, RGD PMID:32071245 RGD:150340708 NCBI chr 7:127,447,192...127,565,987
Ensembl chr 7:127,447,278...127,563,512
JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding ameliorates ISO associated with hepatocellular carcinoma; RGD PMID:27993894 PMID:26902423 RGD:153350132, RGD:153350133 NCBI chr12:16,930,990...16,939,333
Ensembl chr12:16,931,024...16,939,091
JBrowse link
G Car12 carbonic anhydrase 12 ameliorates ISO associated with breast cancer; RGD PMID:29786141 RGD:155226861 NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440
JBrowse link
G Cblb Cbl proto-oncogene B severity ISO associated with stomach carcinoma; RGD PMID:28334634 RGD:150540337 NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839
JBrowse link
G Ccng1 cyclin G1 ISO RGD PMID:30565428 RGD:151361205 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 ameliorates ISO associated with human colon adenocarcinoma cells in a mouse model RGD PMID:28486105 RGD:153323299 NCBI chr 4:157,898,503...157,931,632
Ensembl chr 4:157,899,391...157,931,541
JBrowse link
G Col10a1 collagen type X alpha 1 chain ameliorates ISO associated with H1299 cell RGD PMID:33324550 RGD:150429752 NCBI chr20:38,183,103...38,189,488
Ensembl chr20:38,182,494...38,189,494
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ameliorates ISO associated with colorectal cancer; human cells in mouse model
associated with nasopharynx carcinoma; human cells in mouse model
associated with osteosarcoma and melanoma
RGD PMID:31938138 PMID:16000558 PMID:26498029 PMID:18071913 RGD:151665329, RGD:151893515, RGD:152023752, RGD:152177473 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 ISO RGD PMID:29483153 RGD:151347599 NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 exacerbates ISO associated with tongue squamous cell carcinoma; RGD PMID:24556606 RGD:150429746 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363
JBrowse link
G Fasn fatty acid synthase ISO associated with head and neck squamous cell carcinoma RGD PMID:20604875 RGD:126790467 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit ISO human cells in mouse model RGD PMID:30326930 RGD:153344557 NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034
JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated ISO human cells in mouse model RGD PMID:31142329 RGD:153344574 NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:57,871,110...57,874,557
JBrowse link
G Iqsec1 IQ motif and Sec7 domain ArfGEF 1 ISO human cells in mouse model RGD PMID:18084281 RGD:153344604 NCBI chr 4:123,168,719...123,488,300
Ensembl chr 4:123,168,719...123,488,172
JBrowse link
G Itgav integrin subunit alpha V treatment ISO human cells in rat model RGD PMID:20841470 RGD:152998949 NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 ameliorates ISO associated with breast carcinoma RGD PMID:16568086 RGD:150573808 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 ameliorates ISO associated with clear cell renal cell carcinoma RGD PMID:23982215 RGD:151356974 NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216
JBrowse link
G Mir423 microRNA 423 ISO human cells in mouse model RGD PMID:30326930 RGD:153344557 NCBI chr10:61,914,142...61,914,220
Ensembl chr10:61,914,133...61,914,226
JBrowse link
G Mir494 microRNA 494 ameliorates ISO associated with hepatocellular carcinoma RGD PMID:25820676 PMID:28055013 RGD:155900754, RGD:156430322 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793
JBrowse link
G Nf2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor ISO associated with hepatocellular carcinoma RGD PMID:26443326 RGD:11076529 NCBI chr14:79,627,399...79,710,709
Ensembl chr14:79,627,399...79,710,667
JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 ameliorates ISO associated with mammary carcinoma RGD PMID:20802235 RGD:150520014 NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286
JBrowse link
G Pagr1 Paxip1-associated glutamate-rich protein 1 ISO human cells in mouse model RGD PMID:33833989 RGD:153344568 NCBI chr 1:181,622,698...181,625,024 JBrowse link
G Ptprb protein tyrosine phosphatase, receptor type, B treatment ISO RGD PMID:23899555 RGD:151660352 NCBI chr 7:51,953,375...52,034,751
Ensembl chr 7:51,930,015...52,034,748
JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 ISO human cells in mouse model RGD PMID:20978191 PMID:29809146 RGD:152995469, RGD:152995516 NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426
JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 ISO RGD PMID:29809146 RGD:152995516 NCBI chr10:104,878,487...105,176,986
Ensembl chr10:104,878,487...105,176,983
JBrowse link
G Sf3b4 splicing factor 3B subunit 4 ISO human cells in mouse model RGD PMID:30391496 RGD:155804298 NCBI chr 2:183,732,791...183,737,545
Ensembl chr 2:183,732,754...183,737,959
JBrowse link
G Sox30 SRY-box transcription factor 30 ameliorates ISO RGD PMID:29739711 RGD:151660333 NCBI chr10:30,417,499...30,446,441
Ensembl chr10:30,418,473...30,446,453
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase treatment
ameliorates
ISO associated with breast cancer;
associated with nasopharynx carcinoma;
RGD PMID:15753384 PMID:27078847 RGD:1581400, RGD:150521726 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
Lymphatic Metastasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca13 ATP binding cassette subfamily A member 13 susceptibility ISO DNA:amplification:cds: (human, male) RGD PMID:27366209 RGD:152995256 NCBI chr14:83,873,397...84,376,138
Ensembl chr14:83,873,940...84,375,075
JBrowse link
G Adam28 ADAM metallopeptidase domain 28 ISO associated with breast cancer;DNA:hypermethylation: RGD PMID:25620615 RGD:153298970 NCBI chr15:43,774,463...43,840,726
Ensembl chr15:42,944,467...43,840,672
JBrowse link
G Adgrb1 adhesion G protein-coupled receptor B1 disease_progression ISO associated with stomach cancer; RGD PMID:11172604 RGD:13831357 NCBI chr 7:106,404,827...106,476,902
Ensembl chr 7:106,404,958...106,476,902
JBrowse link
G Aicda activation-induced cytidine deaminase ISO associated with stomach cancer;protein:increased expression:stomach (human) RGD PMID:21538122 RGD:127285638 NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972
JBrowse link
G Angptl4 angiopoietin-like 4 ISO CTD Direct Evidence: therapeutic CTD PMID:17130448 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Anxa1 annexin A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:21401805 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
JBrowse link
G Arhgap5 Rho GTPase activating protein 5 ISO associated with nasopharynx carcinoma;mRNA, protein:increased expression: epithelium of nasopharynx RGD PMID:25961434 RGD:11056278 NCBI chr 6:69,975,904...70,039,299
Ensembl chr 6:69,976,214...70,037,660
JBrowse link
G Asxl1 ASXL transcriptional regulator 1 ISO associated with colorectal cancer RGD PMID:32317519 RGD:126779580 NCBI chr 3:141,814,012...141,881,526
Ensembl chr 3:141,813,433...141,881,538
JBrowse link
G Axl Axl receptor tyrosine kinase ISO associated Pancreatic Neoplasms RGD PMID:19252414 RGD:2325833 NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265
JBrowse link
G Bag1 BAG cochaperone 1 disease_progression ISO associated with Breast Neoplasms:protein:increased expression:breast RGD PMID:18430249 RGD:2292908 NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor ISO associated with stomach cancer; protein:increased expression: : RGD PMID:24752577 RGD:14390158 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060
JBrowse link
G Barhl2 BarH-like homeobox 2 ISO associated with oral squamous cell carcinoma; mRNA:decreased expression:mouth mucosa RGD PMID:27542258 RGD:14390167 NCBI chr14:3,340,465...3,345,362
Ensembl chr14:3,340,465...3,345,353
JBrowse link
G Bcl2 BCL2, apoptosis regulator ISO associated with Breast Neoplasms;protein:increased expression:lymph node RGD PMID:18217456 RGD:2293013 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bik BCL2-interacting killer ISO associated with cholangiocarcinoma;DNA:CNV:: RGD PMID:16865775 RGD:14394820 NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 disease_progression ISO associated with Cervix Neoplasms;mRNA:splice variant
associated with Breast Neoplasms
RGD PMID:17877643 PMID:17285241 RGD:2293098, RGD:2293103 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:29426936 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Brd7 bromodomain containing 7 severity ISO protein:increased expression:lung: RGD PMID:22008115 RGD:9586442 NCBI chr19:18,708,792...18,737,497
Ensembl chr19:18,709,022...18,737,494
JBrowse link
G Bsg basigin disease_progression ISO associated with Breast Neoplasms RGD PMID:16004819 RGD:2289055 NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387
JBrowse link
G Btk Bruton tyrosine kinase disease_progression ISO associated with lung adenocarcinoma;protein:increased expression:lung (human) RGD PMID:31200752 RGD:151347847 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853
JBrowse link
G Cab39 calcium binding protein 39 ISO associated with pancreatic cancer;RNA:increased expression:pancreas RGD PMID:28197410 RGD:14398834 NCBI chr 9:86,463,095...86,524,545
Ensembl chr 9:86,463,095...86,524,544
JBrowse link
G Car9 carbonic anhydrase 9 ISO associated with Cervix Neoplasms RGD PMID:17233814 RGD:2293196 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
JBrowse link
G Casp9 caspase 9 ISO associated with Carcinoma, Non-Small-Cell Lung;DNA:SNP:exon:rs1052576 (human) RGD PMID:17285546 RGD:13434907 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cav1 caveolin 1 disease_progression ISO associated with Melanoma RGD PMID:22134245 RGD:8661767 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cbl Cbl proto-oncogene ISO associated with stomach carcinoma;protein:increased expression:stomach RGD PMID:31611438 RGD:126925223 NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176
JBrowse link
G Cblb Cbl proto-oncogene B ISO associated with stomach carcinoma; RGD PMID:20038312 RGD:150540338 NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839
JBrowse link
G Ccnd2 cyclin D2 ISO associated with colorectal cancer;protein:increased expression:colorectum RGD PMID:19508551 RGD:151665111 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccne1 cyclin E1 ISO associated with Carcinoma, Transitional Cell;protein:decreased expression RGD PMID:16949911 RGD:2289266 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Ccnh cyclin H ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 2:15,835,064...15,855,648
Ensembl chr 2:15,834,833...15,855,819
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 ISO associated with Breast Neoplasms;mRNA:increased expression:lymph node RGD PMID:24301790 RGD:8551816 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
JBrowse link
G Cd274 CD274 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:16530813 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450
JBrowse link
G Cd40 CD40 molecule ISO associated with breast cancer;DNA:snps:5' utr, intron:c.-1T>C, c.51+914T>G (rs1883832, rs4810485) (human) RGD PMID:21912605 RGD:8547780 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd44 CD44 molecule ISO associated with Breast Neoplasms, Colorectal Neoplasms, Stomach Neoplasms;mRNA, protein:splice variant, increased expression:breast, large intestine, stomach RGD PMID:16425351 RGD:2289356 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cdh1 cadherin 1 ISO associated with Cervix Neoplasms
associated with Breast Neoplasms
RGD PMID:18097581 PMID:17649807 RGD:2296046, RGD:2289498 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A ISO associated with Eyelid Neoplasms;
associated with Oral Squamous Cell Carcinoma;
RGD PMID:19628749 PMID:15817070 RGD:8661799, RGD:8662374 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B ISO associated with Breast Neoplasms
associated with non-small cell lung carcinoma
RGD PMID:12015771 PMID:28601655 RGD:2293607, RGD:13673921 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:29426936 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cldn1 claudin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33665778 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
JBrowse link
G Clptm1l CLPTM1-like ISO associated with esophagus squamous cell carcinoma; mRNA:increased expression:esophagus RGD PMID:25480402 RGD:150530497 NCBI chr 1:29,667,545...29,683,530
Ensembl chr 1:29,667,545...29,683,530
JBrowse link
G Clu clusterin ISO associated with breast cancer;DNA:snp:promoter:g.27611345C>G (rs9331888) (human) RGD PMID:22037783 RGD:8963167 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Comt catechol-O-methyltransferase ISO associated with breast cancer;DNA:missense mutation:cds:p.V108/158M (human) RGD PMID:10755383 RGD:8662330 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Crp C-reactive protein susceptibility ISO associated with Breast Neoplasm; DNA:polymorphism: :1846C>T(rs1205)(human) RGD PMID:24633920 RGD:9580226 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Csf1r colony stimulating factor 1 receptor ISO associated with Breast Neoplasms RGD PMID:14734466 RGD:2293711 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 ISO associated with Prostatic Neoplasms RGD PMID:10611340 RGD:4891523 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963
JBrowse link
G Ctnna1 catenin alpha 1 ISO associated with Breast Neoplasms RGD PMID:12047765 RGD:2289795 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910
JBrowse link
G Ctnnb1 catenin beta 1 ISO associated with Breast Neoplasms;protein:decreased expression RGD PMID:17908479 RGD:2289813 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 disease_progression ISO associated with stomach cancer;mRNA:increased expression:stomach (human) RGD PMID:21633638 RGD:152023624 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ISO associated with nasopharynx carcinoma; protein:increased expression:lymph node (human) RGD PMID:16000558 RGD:151893515 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cycs cytochrome c, somatic ISO associated with non-small cell lung carcinoma; protein:decreased expression:serum RGD PMID:25578497 RGD:13792769 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054
JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 severity ISO mRNA, protein:increased expression:mouth (human)
mRNA:increased expression:kidney, lymph nodes (human)
RGD PMID:31253192 PMID:27020590 RGD:151347620, RGD:151347863 NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 disease_progression ISO associated with oral squamous cell carcinoma RGD PMID:29945346 RGD:150429700 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta ISO associated with Carcinoma, Pancreatic Ductal; RGD PMID:22919364 RGD:9589121 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124
JBrowse link
G Ebag9 estrogen receptor binding site associated antigen 9 ISO associated with Prostatic Neoplasm;protein:increased expression:prostate gland, lymph node
associated with Breast Neoplasms;protein:increased expression:breast
RGD PMID:12845666 PMID:12054692 PMID:17187007 RGD:2289856, RGD:2298489, RGD:2289847 NCBI chr 7:75,810,950...75,828,902
Ensembl chr 7:75,810,594...75,861,248
JBrowse link
G Egfr epidermal growth factor receptor treatment ISO associated with Squamous Cell Carcinoma of the Tongue RGD PMID:19380367 RGD:8551769 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 ISO associated with Melanoma;
associated with Esophageal Squamous Cell Carcinoma;
RGD PMID:24658378 PMID:24805087 RGD:9590069, RGD:9590071 NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547
JBrowse link
G Epha2 Eph receptor A2 ISO protein:increased expression:esophagus (human) RGD PMID:33833989 RGD:153344568 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 disease_progression ISO associated with Breast Neoplasms;DNA, protein:polymorphism, increased expression:serum:p.I655V
associated with lung adenocarcinoma; protein:increased expression:lung (human)
CTD Direct Evidence: marker/mechanism
associated with Carcinoma, Transitional Cell;protein:increased expression:urinary bladder
RGD
CTD
PMID:21532492 PMID:21966491 PMID:18237248 PMID:18097576 RGD:153344600, RGD:2289925, RGD:2289926 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 ISO associated with Prostatic Neoplasms;protein:increased expression, altered localization:lymph node, nucleus
associated with head and neck squamous cell carcinoma
RGD PMID:17634423 PMID:20604875 RGD:2289944, RGD:126790467 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 disease_progression
severity
ISO associated with oral squamous cell carcinoma
associated with lung non-small cell carcinoma
associated with colorectal adenocarcinoma
RGD PMID:27444519 PMID:21324275 PMID:16507107 RGD:126781762, RGD:126790471, RGD:126781766 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
JBrowse link
G Fas Fas cell surface death receptor susceptibility ISO associated with Cervix Neoplasms;DNA:polymorphism:promoter:-1377G>A RGD PMID:18068525 RGD:2298509 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fgf1 fibroblast growth factor 1 ISO associated with Cervix Neoplasms;mRNA:increased expression:lymph node RGD PMID:17242701 RGD:2290286 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO associated with breast cancer;DNA:snp:intron:c.109+7033T>A (rs1219648) (human) RGD PMID:20640597 RGD:7394846 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Flt3 Fms related receptor tyrosine kinase 3 disease_progression ISO associated with Prostatic Neoplasms RGD PMID:14566827 RGD:2302210 NCBI chr12:7,623,930...7,699,474
Ensembl chr12:7,623,930...7,699,474
JBrowse link
G Foxa1 forkhead box A1 ISO associated with lung non-small cell carcinoma; mRNA:increased expression: : RGD PMID:29115441 RGD:151665751 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
JBrowse link
G Foxp1 forkhead box P1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25485836 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258
JBrowse link
G Gpx3 glutathione peroxidase 3 ISO associated with stomach carcinoma; DNA:hypermethylation:promoter RGD PMID:23071548 RGD:151665353 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375
JBrowse link
G Hmgb1 high mobility group box 1 IEP associated with Adenocarcinoma, Colon RGD PMID:20616616 RGD:10402080 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO associated with Breast Neoplasms RGD PMID:21590495 RGD:8547712 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ier2 immediate early response 2 IMP RGD PMID:22120713 RGD:153323322 NCBI chr19:23,494,551...23,496,075
Ensembl chr19:23,494,184...23,499,211
JBrowse link
G Il13 interleukin 13 ISO associated with Melanoma, Cutaneous Malignant;mRNA:increased expression:lymph node RGD PMID:17545514 RGD:8549587 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il18 interleukin 18 ISO associated with Breast Neoplasms;protein:increased expression:serum RGD PMID:12902898 RGD:8655867 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Ing4 inhibitor of growth family, member 4 ISO CTD Direct Evidence: therapeutic CTD PMID:27806345 NCBI chr 4:157,841,882...157,850,519
Ensembl chr 4:157,841,951...157,850,265
JBrowse link
G Iqsec1 IQ motif and Sec7 domain ArfGEF 1 disease_progression ISO associated with lung adenocarcinoma; protein:increased expression:lung (human) RGD PMID:21966491 RGD:153344600 NCBI chr 4:123,168,719...123,488,300
Ensembl chr 4:123,168,719...123,488,172
JBrowse link
G Itgb1 integrin subunit beta 1 ISO associated with non-small cell lung carcinoma, RGD PMID:28537888 RGD:13792830 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Kcnj12 potassium inwardly-rectifying channel, subfamily J, member 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34755307 NCBI chr10:45,696,621...45,745,528
Ensembl chr10:45,696,849...45,745,492
JBrowse link
G Kdr kinase insert domain receptor treatment ISO associated with Squamous Cell Carcinoma of the Tongue RGD PMID:19380367 RGD:8551769 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Kiss1 KiSS-1 metastasis-suppressor ISO CTD Direct Evidence: therapeutic CTD PMID:21383688 NCBI chr13:44,775,106...44,780,707
Ensembl chr13:44,774,823...44,780,612
JBrowse link
G Klf7 KLF transcription factor 7 ISO CTD Direct Evidence: therapeutic CTD PMID:37734194 NCBI chr 9:65,433,683...65,526,372
Ensembl chr 9:65,437,167...65,526,261
JBrowse link
G Kmt2d lysine methyltransferase 2D ISO associated with stomach cancer RGD PMID:30177394 RGD:150521710 NCBI chr 7:129,980,744...130,022,088
Ensembl chr 7:129,962,887...130,020,325
JBrowse link
G Lamc2 laminin subunit gamma 2 ISO associated with lung squamous cell carcinoma; RGD PMID:23124251 RGD:13793371 NCBI chr13:65,284,664...65,344,164
Ensembl chr13:65,284,664...65,344,200
JBrowse link
G Lrrc59 leucine rich repeat containing 59 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr10:79,572,295...79,586,953
Ensembl chr10:79,572,317...79,602,533
JBrowse link
G Macir macrophage immunometabolism regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 9:98,420,760...98,440,818
Ensembl chr 9:98,420,376...98,441,733
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:29426936 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
JBrowse link
G Mir125a microRNA 125a ISO associated with stomach cancer; RGD PMID:22322911 RGD:21408544 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710
JBrowse link
G Mir152 microRNA 152 ISO associated with breast cancer RGD PMID:22935141 RGD:19165152 NCBI chr10:81,832,936...81,833,020
Ensembl chr10:81,832,936...81,833,020
JBrowse link
G Mir155 microRNA 155 disease_progression ISO associated with colon cancer RGD PMID:26885061 PMID:29893326 PMID:27856635 RGD:21079444, RGD:21409756, RGD:21079446 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mir187 microRNA 187 ISO associated with oral squamous cell carcinoma; RNA:increased expression:plasma RGD PMID:27542258 RGD:14390167 NCBI chr18:15,731,194...15,731,297
Ensembl chr18:15,731,194...15,731,297
JBrowse link
G Mir224 microRNA 224 ISO associated with colorectal cancer; mRNA:decreased expression:colorectal mucosa: RGD PMID:25919696 RGD:14398749 NCBI chr  X:150,065,088...150,065,169
Ensembl chr  X:150,065,088...150,065,169
JBrowse link
G Mir30a microRNA 30a ISO associated with Colorectal Neoplasms RGD PMID:23486085 RGD:13432035 NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670
JBrowse link
G Mmp2 matrix metallopeptidase 2 disease_progression ISO associated with Tongue Neoplasms
associated with Carcinoma, Ductal, Breast
RGD PMID:23107277 PMID:23280016 RGD:8547824, RGD:8655998 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp3 matrix metallopeptidase 3 susceptibility ISO associated with breast cancer;DNA:deletion:promoter:-1170_-1172delA (human) RGD PMID:15161710 PMID:15161710 RGD:8662937, RGD:8662937 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mmp9 matrix metallopeptidase 9 disease_progression ISO associated with Carcinoma, Non-Small-Cell Lung;protein:increased expression:serum
associated with Tongue Neoplasms
associated with Endometrial Neoplasms;protein:increased expression:endometrium
RGD PMID:20704821 PMID:23107277 PMID:12487935 RGD:5129215, RGD:8547824, RGD:2298523 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Msh2 mutS homolog 2 ISO associated with laryngeal squamous cell carcinoma RGD PMID:24459922 RGD:126848797 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Msln mesothelin ISO CTD Direct Evidence: marker/mechanism CTD PMID:22644300 NCBI chr10:14,771,946...14,781,382
Ensembl chr10:14,771,961...14,777,643
JBrowse link
G Mt1 metallothionein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17418620 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
JBrowse link
G Mta1 metastasis associated 1 ISO associated with Carcinoma, Non-Small-Cell Lung;mRNA:increased expression:lung RGD PMID:11804687 RGD:9588220 NCBI chr 6:132,178,608...132,217,641
Ensembl chr 6:132,178,853...132,217,641
JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Muc1 mucin 1, cell surface associated ISO associated with Common Bile Duct Neoplasms
associated with Esophageal Neoplasms
associated with Carcinoma, Renal Cell;
associated with Gallbladder Neoplasms;protein:altered localization:gallbladder
RGD PMID:16222735 PMID:21339746 PMID:10390012 PMID:11295067 RGD:2324649, RGD:7349383, RGD:7245968, RGD:2324860 NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming ISO associated with chloangiocarcinoma;protein:increased expression:bile duct RGD PMID:16842244 RGD:2325168 NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475
JBrowse link
G Ncam1 neural cell adhesion molecule 1 ISO RGD PMID:10086383 RGD:2326067 NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 ISO associated with Cervix Neoplasms; associated with Endometrial Neoplasms
associated with Breast Neoplasms
RGD PMID:8855975 PMID:8102131 PMID:9036878 RGD:2299062, RGD:2299077, RGD:2299061 NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 ISO associated with Cervix Neoplasms; associated with Endometrial Neoplasms RGD PMID:8855975 RGD:2299062 NCBI chr10:78,898,097...78,903,514
Ensembl chr10:78,897,770...78,903,538
JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility ISO associated with Breast Neoplasms;DNA:polymorphisms:promoter, exon:-786T>C,p.E298D (human) RGD PMID:17262178 RGD:2292070 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase ISO associated with breast cancer;DNA:missense mutation:cds:p.S326C (rs1052133) (human) RGD PMID:18977234 RGD:8657156 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
G Pagr1 Paxip1-associated glutamate-rich protein 1 disease_progression ISO protein:decreased expression:esophagus (human) RGD PMID:33833989 RGD:153344568 NCBI chr 1:181,622,698...181,625,024 JBrowse link
G Pdgfa platelet derived growth factor subunit A ISO associated with Breast Neoplasms;mRNA:increased expression:breast RGD PMID:8619189 RGD:2292155 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO associated with Breast Neoplasms;mRNA:increased expression:lymph node RGD PMID:17674348 RGD:2292173 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 ISO associated with non-small cell lung carcinoma;mRNA:increased expression:blood serum RGD PMID:25064732 RGD:13503320 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623
JBrowse link
G Pdpn podoplanin ISO associated with Breast Neoplasms
associated with Cervix Neoplasms
RGD PMID:18165897 PMID:16528371 RGD:2292231, RGD:2292237 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 ISO associated with Breast Neoplasms
associated with Cervix Neoplasms
RGD PMID:16243812 PMID:18191186 RGD:2302868, RGD:2302867 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO associated with Colorectal Neoplasms RGD PMID:25550888 RGD:13432030 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta ISO associated with Colorectal Neoplasms RGD PMID:25550888 RGD:13432030 NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663
JBrowse link
G Pip5k1a phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:34755307 NCBI chr 2:182,628,299...182,671,584
Ensembl chr 2:182,628,300...182,671,598
JBrowse link
G Pou5f1 POU class 5 homeobox 1 ISO associated with Seminoma; associated with Carcinoma, Embryonal RGD PMID:15386301 RGD:2292442 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma ISO associated with Cholangiocarcinoma;protein:increased expression:bile duct epithelium RGD PMID:20021832 RGD:2317459 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Prex1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 ISO associated with Prostatic Neoplasms RGD PMID:19305425 RGD:2314605 NCBI chr 3:155,306,950...155,456,688
Ensembl chr 3:155,306,950...155,456,688
JBrowse link
G Pten phosphatase and tensin homolog ISO associated with Prostatic Neoplasms;protein:decreased expression:prostate
associated with Breast Neoplasms
RGD PMID:17163422 PMID:17919877 RGD:2292507, RGD:2292499 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO associated with Biliary Tract Neoplasms
associated with carcinoma, non-small-cell lung; DNA:SNP: :929G>C(human)
associated with Breast Neoplasms
RGD PMID:18159174 PMID:20016751 PMID:18353210 RGD:2317165, RGD:5135471, RGD:2300128 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptk2 protein tyrosine kinase 2 ISO associated with lung squamous cell carcinoma; protein:increased tyrosine phosphorylation:lymph node RGD PMID:23906871 RGD:152176664 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Ptpn13 protein tyrosine phosphatase, non-receptor type 13 ISO associated with lung squamous cell carcinoma; protein:decreased expression:lymph node RGD PMID:23906871 RGD:152176664 NCBI chr14:6,108,202...6,282,619
Ensembl chr14:6,108,211...6,282,563
JBrowse link
G Ramp2 receptor activity modifying protein 2 disease_progression ISO associated with colorectal cancer; protein:increased expression:lymph node (human) RGD PMID:23634287 RGD:151708733 NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829
JBrowse link
G Ramp3 receptor activity modifying protein 3 ISO associated with colorectal cancer; protein:increased expression:lymph node (human) RGD PMID:23634287 RGD:151708733 NCBI chr14:81,527,404...81,544,905
Ensembl chr14:81,527,385...81,544,902
JBrowse link
G Rassf2 Ras association domain family member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17013896 NCBI chr 3:119,244,288...119,280,462
Ensembl chr 3:119,245,821...119,280,431
JBrowse link
G Rbm10 RNA binding motif protein 10 ISO associated with lung adenocarcinoma;DNA:missense mutation:exon:p.R241C (c.763C>T) (human) RGD PMID:30405763 RGD:151356993 NCBI chr  X:1,540,399...1,572,571
Ensembl chr  X:1,540,398...1,572,575
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO associated with Prostatic Neoplasms;protein:altered localization:nucleus, prostate gland RGD PMID:17020979 RGD:2298757 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Ret ret proto-oncogene ISO associated with Pancreatic Neoplasms RGD PMID:18652760 RGD:2324925 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176
JBrowse link
G Rhoa ras homolog family member A ISO associated with Bladder Neoplasms;protein:increased expression:lymph node
associated with colorectal cancer
RGD PMID:12855641 PMID:17597401 RGD:2298872, RGD:13432052 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 ISO associated with breast ductal carcinoma; protein:increased expression:breast tumor, lymph node (human) RGD PMID:20978191 RGD:152995469 NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426
JBrowse link
G Runx1 RUNX family transcription factor 1 ISO associated with Carcinoid Tumor RGD PMID:21636701 RGD:126779567 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542
JBrowse link
G Sfn stratifin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314
JBrowse link
G Skp2 S-phase kinase associated protein 2 ISO associated with Endometrial Neoplasms;protein:increased expression:endometrium RGD PMID:16080017 RGD:2315043 NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338
JBrowse link
G Slc22a22 solute carrier family 22 member 22 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 7:88,720,425...88,750,111
Ensembl chr 7:88,720,427...88,750,111
JBrowse link
G Slc7a5 solute carrier family 7 member 5 severity ISO associated with stomach carcinoma
associated with gastric adenocarcinoma;protein:increased expression: :
RGD PMID:25908107 PMID:21501294 RGD:11052781, RGD:151361203 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
JBrowse link
G Smad4 SMAD family member 4 ISO associated with Breast Neoplasms RGD PMID:11809701 RGD:2300007 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Smo smoothened, frizzled class receptor ISO associated with colorectal cancer RGD PMID:30784110 RGD:150520177 NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829
JBrowse link
G Sncg synuclein, gamma ISO RGD PMID:15221989 RGD:6478801 NCBI chr16:9,700,513...9,705,751
Ensembl chr16:9,700,514...9,705,368
JBrowse link
G Socs2 suppressor of cytokine signaling 2 ISO associated with Prostatic Neoplasms RGD PMID:16707422 RGD:2298925 NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548
JBrowse link
G Socs3 suppressor of cytokine signaling 3 ISO associated with Breast Neoplasms RGD PMID:18097573 RGD:2298901 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Sod2 superoxide dismutase 2 disease_progression ISO associated with tongue neoplasms;
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:10853026 PMID:19381893 PMID:20618948 PMID:20618948 RGD:8547519 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sox2 SRY-box transcription factor 2 disease_progression ISO associated with Breast Neoplasms RGD PMID:24382260 RGD:8661670 NCBI chr 2:117,536,929...117,539,340
Ensembl chr 2:117,536,929...117,539,338
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO associated with colon adenocarcinoma, RGD PMID:21282564 RGD:150520218 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G St14 ST14 transmembrane serine protease matriptase ISO associated with Endometrial Neoplasms RGD PMID:19443387 RGD:2315087 NCBI chr 8:29,540,805...29,581,704
Ensembl chr 8:29,540,811...29,581,517
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549414 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stk11 serine/threonine kinase 11 ISO associated with Breast Neoplasms;protein:decreased expression RGD PMID:12114407 RGD:2291948 NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
JBrowse link
G Tert telomerase reverse transcriptase disease_progression ISO associated with lung non-small cell carcinoma; RGD PMID:11679180 RGD:152977755 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 ISO associated with Endometrial Neoplasms;protein:increased expression:endometrium RGD PMID:12487935 RGD:2298523 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 ISO associated with Breast Neoplasms;mRNA:increased expression:breast RGD PMID:12828172 RGD:2290437 NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839
JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 ISO associated with Breast Neoplasms;mRNA:increased expression:breast RGD PMID:12828172 RGD:2290437 NCBI chr 4:148,306,021...148,312,558
Ensembl chr 4:148,304,490...148,312,558
JBrowse link
G Tlr4 toll-like receptor 4 ISO associated with Carcinoma, Ductal, Breast; RGD PMID:23338716 RGD:7794684 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tp53 tumor protein p53 ISO associated with Penile Neoplasms
associated with Carcinoma, Squamous Cell;
associated with Breast Neoplasms;DNA:missense mutation, duplication:cds, intron:p.R72P
RGD PMID:18268397 PMID:18059331 PMID:18230179 RGD:2290533, RGD:8547790, RGD:2290534 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822
JBrowse link
G Trmt11 tRNA methyltransferase 11 homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 1:27,054,437...27,109,765
Ensembl chr 1:27,054,420...27,201,610
JBrowse link
G Tsc2 TSC complex subunit 2 ISO associated with Breast Neoplasms RGD PMID:15951164 RGD:11568707 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951
JBrowse link
G Tshr thyroid stimulating hormone receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:9062474 NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538
JBrowse link
G Ttr transthyretin ISO associated with colorectal cancer;protein:decreased expresion:blood serum (human) RGD PMID:21074777 RGD:151665155 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
JBrowse link
G Tymp thymidine phosphorylase ISO associated with Cholangiocarcinoma
associated with Breast Neoplasms
RGD PMID:11927969 PMID:10685502 RGD:2325027, RGD:2293725 NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874
Ensembl chr 7:120,438,770...120,443,874
JBrowse link
G Vegfa vascular endothelial growth factor A ISO associated with Cervix Neoplasms
associated with Breast neoplasms;
RGD PMID:19783962 PMID:17597103 RGD:2315454, RGD:7421574 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vegfc vascular endothelial growth factor C exacerbates
disease_progression
ISO associated with Carcinoma, Transitional Cell;protein:increased expression:urinary bladder
associated with pancreatic adenocarcinoma;protein:increased expression:pancreas (human)
associated with Lymphatic Metastasis;
associated with thyroid diseases;mRNA:increased expression:thyroid gland:
associated with Breast Neoplasms
associated with Prostatic Neoplasms
associated with Cervix Neoplasms
RGD PMID:17034609 PMID:18061373 PMID:15289890 PMID:12203051 PMID:19923084 More... RGD:2315484, RGD:155630642, RGD:7488946, RGD:7483611, RGD:2315469, RGD:2315474, RGD:2315475 NCBI chr16:37,712,251...37,827,845
Ensembl chr16:37,712,262...37,827,848
JBrowse link
G Vegfd vascular endothelial growth factor D ISO associated with Breast Neoplasms
associated with Cervix Neoplasms
RGD PMID:17951197 PMID:19589137 RGD:2315480, RGD:2315475 NCBI chr  X:30,073,122...30,108,413
Ensembl chr  X:30,074,163...30,108,295
JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 ISO associated with lung non-small cell carcinoma;
associated with esophagus squamous cell carcinoma;
RGD PMID:31281482 PMID:24626331 RGD:21081513, RGD:21081532 NCBI chr10:54,282,092...54,299,908
Ensembl chr10:54,282,105...54,298,929
JBrowse link
Neoplasm Micrometastasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cycs cytochrome c, somatic ISO associated with non-small cell lung carcinoma; protein:decreased expression:serum RGD PMID:25578497 RGD:13792769 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054
JBrowse link
Neoplasm Seeding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdh1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27224422 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19047
    disease of cellular proliferation 7792
      Neoplastic Processes 740
        Neoplasm Metastasis 501
          Bone Metastasis 7
          Circulating Neoplastic Cells 1
          Extranodal Extension 0
          Liver Metastasis 42
          Lymphatic Metastasis 161
          Neoplasm Micrometastasis 1
          Neoplasm Seeding 1
          Unknown Primary Neoplasms 0
          leptomeningeal metastasis 0
          lung metastasis 31
Path 2
Term Annotations click to browse term
  disease 19047
    Pathological Conditions, Signs and Symptoms 13529
      Pathologic Processes 8238
        Neoplastic Processes 740
          Neoplasm Metastasis 501
            Bone Metastasis 7
            Circulating Neoplastic Cells 1
            Extranodal Extension 0
            Liver Metastasis 42
            Lymphatic Metastasis 161
            Neoplasm Micrometastasis 1
            Neoplasm Seeding 1
            Unknown Primary Neoplasms 0
            leptomeningeal metastasis 0
            lung metastasis 31
paths to the root