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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Hypokinesia
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Accession:DOID:9000831 term browser browse the term
Definition:Slow or diminished movement of body musculature. It may be associated with BASAL GANGLIA DISEASES; MENTAL DISORDERS; prolonged inactivity due to illness; and other conditions.
Synonyms:exact_synonym: Antiorthostatic Hypokinesia;   Antiorthostatic Hypokinesias;   Bradykinesia;   Bradykinesias;   Hypodynamia
 primary_id: MESH:D018476

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Hypokinesia term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOD apolipoprotein D ISO CTD Direct Evidence: marker/mechanism CTD PMID:21688324 NCBI chr15:89,612,210...89,624,038
Ensembl chr15:89,612,040...89,624,012 		JBrowse link
G GCH1 GTP cyclohydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17368676 NCBI chr24:32,029,997...32,079,656
Ensembl chr24:32,027,648...32,079,490 		JBrowse link
G REL REL proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: therapeutic CTD PMID:31481676 NCBI chr14:46,068,212...46,097,226
Ensembl chr14:46,068,014...46,096,802 		JBrowse link
G SLC39A14 solute carrier family 39 member 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36152728 NCBI chr 8:20,446,756...20,502,585 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15417
    Pathological Conditions, Signs and Symptoms 12061
      Signs and Symptoms 10142
        Neurologic Manifestations 9819
          Dyskinesias 2140
            Hypokinesia 4
              German Syndrome 0
Path 2
Term Annotations click to browse term
  disease 15417
    disease of anatomical entity 15080
      nervous system disease 13230
        central nervous system disease 11819
          brain disease 11089
            movement disease 2514
              Dyskinesias 2140
                Hypokinesia 4
                  German Syndrome 0
paths to the root