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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Postoperative Complications
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Accession:DOID:9000790 term browser browse the term
Definition:Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
Synonyms:exact_synonym: Postoperative Complication
 primary_id: MESH:D011183



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Postoperative Complications term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin spontaneous ISO RGD PMID:23225108 RGD:11035295 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Bche butyrylcholinesterase ISO CTD Direct Evidence: marker/mechanism CTD PMID:6039104 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G F7 coagulation factor VII ISO CTD Direct Evidence: therapeutic CTD PMID:12707733 NCBI chr16:76,489,775...76,500,636
Ensembl chr16:76,489,717...76,500,610
JBrowse link
G Nppb natriuretic peptide B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23019395 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Pf4 platelet factor 4 disease_progression ISO RGD PMID:20691844 RGD:329901811 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:4371370 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
Anastomotic Leak term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epo erythropoietin treatment ISO RGD PMID:22149012 RGD:10400902 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
Cardiac Allograft Vasculopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F3 coagulation factor III, tissue factor IEP RGD PMID:9916935 RGD:11341701 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K ISO RGD PMID:21489814 RGD:155260371 NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997
JBrowse link
G Pdgfd platelet derived growth factor D ISO RGD PMID:19213942 RGD:9854642 NCBI chr 8:3,488,448...3,722,395
Ensembl chr 8:3,488,423...3,722,395
JBrowse link
Chronic Allograft Dysfunction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor treatment IEP RGD PMID:22217518 PMID:23769041 RGD:7245568, RGD:8695995 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G C3 complement C3 treatment IDA RGD PMID:25122638 RGD:11040803 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G Cd40 CD40 molecule treatment IDA RGD PMID:22826618 RGD:11352297 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd40lg CD40 ligand treatment IDA liver RGD PMID:22826618 RGD:11352297 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G F7 coagulation factor VII treatment ISO human protein in a rat model RGD PMID:12095034 RGD:11049508 NCBI chr16:76,489,775...76,500,636
Ensembl chr16:76,489,717...76,500,610
JBrowse link
G Hmgb1 high mobility group box 1 treatment IEP RGD PMID:22217518 RGD:7245568 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 ameliorates IMP RGD PMID:24312257 RGD:401700379 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340
JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment IDA RGD PMID:23985719 RGD:10041002 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Tnf tumor necrosis factor treatment IMP RGD PMID:24598936 RGD:10450586 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
Chronic Allograft Nephropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 IEP RGD PMID:20176611 RGD:11541086 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
JBrowse link
G Alb albumin disease_progression ISO RGD PMID:24370342 RGD:11035281 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO RGD PMID:17298994 RGD:7241819 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccn2 cellular communication network factor 2 disease_progression IEP mRNA, protein:increased expression:kidney (rat) RGD PMID:19921985 RGD:150517553 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Clu clusterin treatment IEP RGD PMID:22494435 RGD:9068431 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cs citrate synthase treatment IDA RGD PMID:20005400 RGD:243048470 NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO RGD PMID:22845765 RGD:7241226 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mmp7 matrix metallopeptidase 7 treatment IDA RGD PMID:18209025 RGD:9685339 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
JBrowse link
G Pdgfa platelet derived growth factor subunit A IEP RGD PMID:11889420 RGD:11080974 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link
G Pdgfb platelet derived growth factor subunit B IEP mRNA:increased expression:kidney: RGD PMID:15785371 PMID:11889420 RGD:10449491, RGD:11080974 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha IEP RGD PMID:11889420 RGD:11080974 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta IEP RGD PMID:11889420 RGD:11080974 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Plau plasminogen activator, urokinase ISO protein:increased secretion:T lymphocyte (human) RGD PMID:16387096 RGD:7241259 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma ISO protein:increased expression:kidney: RGD PMID:16221712 RGD:13208600 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Serpine1 serpin family E member 1 treatment ISO protein:increased expression:kidney: RGD PMID:16221712 PMID:18192922 RGD:13208600, RGD:13208601 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
Chronic Lung Allograft Dysfunction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epas1 endothelial PAS domain protein 1 IEP mRNA:increased expression:lung RGD PMID:22305384 RGD:10395369 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
contractures, pterygia, and spondylocarpotarsal fusion syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrng cholinergic receptor nicotinic gamma subunit ISO ClinVar Annotator: match by term: CHRNG-related disorder
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:16826520 PMID:16826531 PMID:22167768 PMID:24038971 PMID:24254455 More... NCBI chr 9:87,878,085...87,884,193
Ensembl chr 9:87,878,085...87,914,482
JBrowse link
contractures, pterygia, and spondylocarpotarsal fusion syndrome 1A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myh3 myosin heavy chain 3 ISO ClinVar Annotator: match by term: Contractures, pterygia, and spondylocarpotarsal fusion syndrome 1A | ClinVar Annotator: match by term: Contractures, pterygia, and variable skeletal fusions syndrome 1A
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:9536098 PMID:17576681 PMID:18414213 PMID:18470895 PMID:25741868 More... NCBI chr10:51,770,177...51,793,994
Ensembl chr10:51,770,177...51,793,992
JBrowse link
contractures, pterygia, and spondylocarpotarsal fusion syndrome 1B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrna1 cholinergic receptor nicotinic alpha 1 subunit ISO ClinVar Annotator: match by term: Autosomal recessive multiple pterygium syndrome ClinVar PMID:25741868 PMID:28492532 NCBI chr 3:58,454,763...58,469,832
Ensembl chr 3:58,454,744...58,469,840
JBrowse link
G Chrnd cholinergic receptor nicotinic delta subunit ISO ClinVar Annotator: match by term: Autosomal recessive multiple pterygium syndrome ClinVar PMID:25741868 PMID:28492532 NCBI chr 9:87,862,417...87,870,833
Ensembl chr 9:87,862,407...87,870,833
JBrowse link
G Chrng cholinergic receptor nicotinic gamma subunit ISO ClinVar Annotator: match by term: Autosomal recessive multiple pterygium syndrome ClinVar PMID:15704180 PMID:16199547 PMID:16826520 PMID:16826531 PMID:22167768 More... NCBI chr 9:87,878,085...87,884,193
Ensembl chr 9:87,878,085...87,914,482
JBrowse link
G Myh3 myosin heavy chain 3 ISO ClinVar Annotator: match by term: CONTRACTURES, PTERYGIA, AND SPONDYLOCARPOTARSAL FUSION SYNDROME 1B | ClinVar Annotator: match by term: Contractures, pterygia, and variable skeletal fusions syndrome 1B OMIM
ClinVar
PMID:9536098 PMID:17576681 PMID:18414213 PMID:25741868 PMID:25741870 More... NCBI chr10:51,770,177...51,793,994
Ensembl chr10:51,770,177...51,793,992
JBrowse link
Delayed Emergence from Anesthesia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btbd1 BTB domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16115977 NCBI chr 1:135,734,549...135,773,067
Ensembl chr 1:135,734,589...135,771,981
JBrowse link
G Zfand6 zinc finger AN1-type containing 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16115977 NCBI chr 1:138,581,002...138,652,052
Ensembl chr 1:138,581,002...138,651,939
JBrowse link
Gastric Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kit KIT proto-oncogene receptor tyrosine kinase IEP mRNA,protein:decreased expression:stomach: RGD PMID:20040059 RGD:12911222 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Kitlg KIT ligand IEP mRNA:decreased expression:stomach: RGD PMID:20040059 RGD:12911222 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
JBrowse link
Graft Occlusion, Vascular term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egr1 early growth response 1 treatment IMP RGD PMID:23586030 RGD:10395312 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Hmox1 heme oxygenase 1 ISO RGD PMID:12958201 RGD:1598395 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO associated with Renal Insufficiency; mRNA:increased expression:arteriovenous fistula (mouse) RGD PMID:20598569 RGD:7207202 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility ISO DNA:repeats:intron RGD PMID:17365407 RGD:11533930 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: therapeutic CTD PMID:8025938 PMID:8416330 PMID:10392865 PMID:11041470 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
Intestinal Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme IEP RGD PMID:15001561 RGD:13515113 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Agt angiotensinogen IEP protein:increased expression:plasma RGD PMID:15001561 RGD:13515113 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Ahr aryl hydrocarbon receptor treatment IEP RGD PMID:22079846 PMID:37387514 RGD:401794136, RGD:407419876 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Atp5f1d ATP synthase F1 subunit delta treatment IEP RGD PMID:24232000 RGD:13792678 NCBI chr 7:9,560,604...9,565,919
Ensembl chr 7:9,560,608...9,565,929
JBrowse link
G Casp3 caspase 3 treatment IEP RGD PMID:23946597 RGD:13782356 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 treatment IEP RGD PMID:23946597 RGD:13782356 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP mRNA:increased expression:small intestine RGD PMID:18475188 RGD:2307016 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cd14 CD14 molecule IEP protein:increased expression:heart, kidney, liver, lung RGD PMID:22493902 RGD:9685194 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cldn1 claudin 1 IEP protein:decreased expression:colon: RGD PMID:19929946 RGD:2325127 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
JBrowse link
G Cldn3 claudin 3 IEP protein:decreased expression:colon: RGD PMID:19929946 RGD:2325127 NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001
JBrowse link
G Cldn5 claudin 5 IEP protein:decreased expression:colon: RGD PMID:19929946 RGD:2325127 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992
JBrowse link
G Crp C-reactive protein IEP protein:increased expression:intestine: RGD PMID:17981193 RGD:5129536 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Csf3 colony stimulating factor 3 treatment ISO RGD PMID:9117128 RGD:11039476 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 treatment IEP RGD PMID:22079846 RGD:401794136 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G F7 coagulation factor VII ISO human protein in a rat model RGD PMID:22920553 RGD:11041662 NCBI chr16:76,489,775...76,500,636
Ensembl chr16:76,489,717...76,500,610
JBrowse link
G Faslg Fas ligand treatment IEP RGD PMID:29170412 RGD:13792603 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Gpt glutamic--pyruvic transaminase IEP protein:increased expression:serum RGD PMID:16557159 RGD:401717563 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Hmgb1 high mobility group box 1 IEP RGD PMID:22093738 RGD:10402181 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565
JBrowse link
G Hmox1 heme oxygenase 1 treatment IEP RGD PMID:19362701 RGD:10766423 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hp haptoglobin treatment IEP RGD PMID:11922743 RGD:11041790 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment IEP RGD PMID:12095141 PMID:22079846 RGD:11522715, RGD:401794136 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il6 interleukin 6 treatment IDA
IEP
RGD PMID:11959089 PMID:22079846 RGD:11062110, RGD:401794136 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jak2 Janus kinase 2 IMP RGD PMID:22777122 RGD:10403072 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Lbp lipopolysaccharide binding protein IEP protein:increased expression:heart, kidney, liver, lung RGD PMID:22493902 RGD:9685194 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586
JBrowse link
G Mbl2 mannose binding lectin 2 severity ISO DNA:polymorphisms:exon: RGD PMID:19477015 RGD:12910933 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Mir155 microRNA 155 ISO miRNA:increased expression:Peyer's patch RGD PMID:30206757 RGD:21409753 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mir21 microRNA 21 IEP RGD PMID:30309483 RGD:41410822 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Nfkbia NFKB inhibitor alpha treatment IEP RGD PMID:22079846 RGD:401794136 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos3 nitric oxide synthase 3 treatment IDA RGD PMID:16610051 RGD:7777112 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IEP RGD PMID:28382390 RGD:13440093 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 disease_progression IEP mRNA:decreased expression:liver (rat) RGD PMID:23331901 RGD:15042883 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Parg poly (ADP-ribose) glycohydrolase treatment IMP RGD PMID:15791006 RGD:13514040 NCBI chr16:7,436,429...7,544,276
Ensembl chr16:7,436,476...7,544,273
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A ISO mRNA:increased expression:jejunum (human) RGD PMID:20965186 RGD:9999150 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:15187522 RGD:11250409 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit treatment IEP RGD PMID:22079846 RGD:401794136 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Serpinc1 serpin family C member 1 treatment IEP RGD PMID:21046505 RGD:11035258 NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293
JBrowse link
G Serpine1 serpin family E member 1 IDA protein:increased activity:plasma (rat) RGD PMID:12717359 RGD:11081012 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Socs1 suppressor of cytokine signaling 1 treatment IEP RGD PMID:27538408 RGD:151347179 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
JBrowse link
G Tnf tumor necrosis factor treatment IEP RGD PMID:22079846 RGD:401794136 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Traf6 TNF receptor associated factor 6 IEP RGD PMID:27538408 RGD:151347179 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 ameliorates IDA associated with mesenteric vascular occlusion; RGD PMID:18091551 RGD:127284848 NCBI chr 9:12,763,819...12,779,285
Ensembl chr 9:12,763,819...12,779,203
JBrowse link
G Vwf von Willebrand factor IEP protein:increased expression:plasma: RGD PMID:10365842 RGD:11080742 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539
JBrowse link
G Xdh xanthine dehydrogenase treatment IEP RGD PMID:23010742 RGD:13209016 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link
Kidney Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme IMP RGD PMID:21680852 RGD:6893484 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Ace2 angiotensin converting enzyme 2 IEP mRNA:decreased expression:kidney RGD PMID:20528771 RGD:9685432 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Acta1 actin, alpha 1, skeletal muscle ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chr19:51,883,709...51,886,735
Ensembl chr19:51,883,715...51,886,742
JBrowse link
G Acvr2b activin A receptor type 2B treatment ISO human construct in rat model RGD PMID:27732750 RGD:329322881 NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:119,138,812...119,170,458
JBrowse link
G Adam17 ADAM metallopeptidase domain 17 treatment IEP RGD PMID:22015440 RGD:13703100 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
JBrowse link
G Adam2 ADAM metallopeptidase domain 2 IEP RGD PMID:11967014 RGD:10047130 NCBI chr15:40,242,651...40,284,025
Ensembl chr15:40,242,783...40,283,952
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 IEP RGD PMID:18272597 RGD:9684850 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing treatment ISO RGD PMID:21412771 RGD:8695946 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Adm adrenomedullin treatment IEP
ISO
protein:increased expression:serum: RGD PMID:20538296 PMID:20538296 RGD:7364948, RGD:7364948 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 ISO RGD PMID:31089212 RGD:27226686 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO RGD PMID:22022451 RGD:7241603 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Anxa1 annexin A1 treatment IDA RGD PMID:20953576 RGD:7421585 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Anxa5 annexin A5 ISO RGD PMID:21918686 RGD:7242028 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 treatment IEP RGD PMID:26362957 RGD:13703110 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Apoa1 apolipoprotein A1 treatment ISO RGD PMID:18535924 RGD:7241574 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Atm ATM serine/threonine kinase IEP protein:increased expression:kidney RGD PMID:22768306 RGD:10053607 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:23151253 RGD:10054101 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP RGD PMID:18221257 PMID:29285062 RGD:2293026, RGD:13792599 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bdkrb1 bradykinin receptor B1 ISO RGD PMID:18725957 RGD:7241559 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
JBrowse link
G Becn1 beclin 1 treatment IEP RGD PMID:26412257 RGD:11561958 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger ISO mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690
JBrowse link
G Bnip3 BCL2 interacting protein 3 IEP mRNA, protein:increased expression:kidney RGD PMID:23698117 RGD:11561968 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G C3 complement C3 treatment IEP RGD PMID:19691975 RGD:7411689 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G Calca calcitonin-related polypeptide alpha IMP RGD PMID:19194162 RGD:7204479 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Casp3 caspase 3 treatment IEP RGD PMID:23151253 RGD:10054101 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 IEP RGD PMID:17596683 RGD:5684536 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 treatment ISO RGD PMID:22160777 RGD:7247742 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 ameliorates
treatment
ISO
IDA
mRNA, protein:increased expression:kidney, lung, serum RGD PMID:24920753 PMID:20396927 PMID:18650485 RGD:329845564, RGD:4891433, RGD:11526113 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccn1 cellular communication network factor 1 ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Cd14 CD14 molecule ISO mRNA,protein:increased expression:kidney RGD PMID:10966493 RGD:7204444 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd40 CD40 molecule treatment IMP RGD PMID:25993320 RGD:11251055 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cfb complement factor B ISO RGD PMID:16467447 PMID:12538716 RGD:7242709, RGD:7242734 NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
JBrowse link
G Cfh complement factor H treatment IEP
ISO
protein:decreased expression:serum: RGD PMID:20538296 PMID:20538296 RGD:7364948, RGD:7364948 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838
JBrowse link
G Ciita class II, major histocompatibility complex, transactivator ISO RGD PMID:14569092 RGD:7242896 NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440
JBrowse link
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 ISO mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr  X:67,350,376...67,355,072
Ensembl chr  X:67,350,373...67,355,162
JBrowse link
G Col1a1 collagen type I alpha 1 chain ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col3a1 collagen type III alpha 1 chain ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Csf1 colony stimulating factor 1 ISO mRNA:increased expression:kidney RGD PMID:23143303 PMID:19196448 RGD:7257565, RGD:7257570 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
JBrowse link
G Csf1r colony stimulating factor 1 receptor ISO RGD PMID:23143303 RGD:7257565 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 ISO RGD PMID:22189844 PMID:9407517 RGD:7204675, RGD:7204727 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 ISO RGD PMID:20038794 RGD:7257679 NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 IEP protein:increased expression:kidney RGD PMID:29073721 RGD:13825150 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 treatment IMP RGD PMID:23552495 RGD:7244372 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Daxx death-domain associated protein ISO protein:increased expression:kidney: RGD PMID:18480747 PMID:18480747 RGD:9587836, RGD:9587836 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 ISO protein:increased expression:kidney (mouse) RGD PMID:31383731 RGD:151347540 NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468
JBrowse link
G Dhfr dihydrofolate reductase treatment IEP mRNA,protein:decreased expression:kidney: RGD PMID:18408363 RGD:11040540 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
JBrowse link
G Drd3 dopamine receptor D3 treatment IDA RGD PMID:25989500 RGD:13506961 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Eed embryonic ectoderm development ISO mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr 1:143,867,875...143,895,008
Ensembl chr 1:143,867,875...143,894,974
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 IEP mRNA, protein:decreased expression:kidney RGD PMID:19349364 RGD:11252083 NCBI chr19:52,867,900...52,907,308
Ensembl chr19:52,869,486...52,907,777
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 IEP mRNA, protein:decreased expression:kidney RGD PMID:19349364 RGD:11252083 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
JBrowse link
G Elane elastase, neutrophil expressed treatment IMP RGD PMID:16980042 RGD:10450580 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100
JBrowse link
G Eng endoglin IEP
ISO
mRNA, protein:increased expression:kidney (rat) RGD PMID:16751653 PMID:16751653 RGD:7248779, RGD:7248779 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
JBrowse link
G Ep300 E1A binding protein p300 IEP protein:altered localization:kidney (rat) RGD PMID:23936185 RGD:7257563 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Epo erythropoietin treatment ISO RGD PMID:19961832 PMID:25581532 RGD:10401077, RGD:11041698 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G F3 coagulation factor III, tissue factor IEP protein:decreased expression:lung RGD PMID:25883098 RGD:11341735 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Fas Fas cell surface death receptor treatment IEP RGD PMID:29285062 RGD:13792599 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand treatment IEP RGD PMID:29285062 RGD:13792599 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fcgr1a Fc gamma receptor 1A treatment ISO RGD PMID:22402584 RGD:9685699 NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994
JBrowse link
G Fga fibrinogen alpha chain IEP mRNA,protein:increased expression:kidney RGD PMID:21685370 RGD:7175292 NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528
JBrowse link
G Fgb fibrinogen beta chain treatment IEP
ISO
mRNA, protein:increased expression:kidney RGD PMID:21685370 PMID:21685370 RGD:7175292, RGD:7175292 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 exacerbates
ameliorates
ISO
IMP
protein:increased phosphorylation:kidney (mouse) RGD PMID:20591940 PMID:22688984 PMID:29344510 PMID:32523960 RGD:155663667, RGD:155882537, RGD:155782904, RGD:155782882 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Fgg fibrinogen gamma chain IEP mRNA,protein:increased expression:kidney RGD PMID:21685370 RGD:7175292 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
JBrowse link
G Fn1 fibronectin 1 IEP RGD PMID:11352844 RGD:7205629 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:19095962 RGD:7242184 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase IEP RGD PMID:17250641 RGD:2307361 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gfer growth factor, augmenter of liver regeneration treatment IEP
ISO
protein:increased expression:kidney: RGD PMID:20332418 PMID:20332418 RGD:9685723, RGD:9685723 NCBI chr10:13,718,489...13,721,782
Ensembl chr10:13,718,489...13,720,869
JBrowse link
G Glo1 glyoxalase 1 IMP RGD PMID:19211689 RGD:7242566 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
JBrowse link
G Gpx3 glutathione peroxidase 3 IEP protein:decreased expression:kidney
mRNA:decreased expression:kidney
RGD PMID:37033969 PMID:22442209 RGD:401827821, RGD:401827906 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
JBrowse link
G Gsr glutathione-disulfide reductase treatment IEP RGD PMID:24630969 RGD:10401866 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gstm1 glutathione S-transferase mu 1 IEP mRNA, protein:decreased expression:kidney RGD PMID:29137244 RGD:158014894 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstt1 glutathione S-transferase theta 1 IEP protein:decreased expression:kidney RGD PMID:37033969 RGD:401827821 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G H2ax H2A.X variant histone treatment IEP RGD PMID:23726287 RGD:8693706 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239
JBrowse link
G Has1 hyaluronan synthase 1 IEP RGD PMID:22529164 RGD:9588636 NCBI chr 1:58,693,411...58,705,653
Ensembl chr 1:58,693,411...58,705,397
JBrowse link
G Has2 hyaluronan synthase 2 IEP RGD PMID:22529164 RGD:9588636 NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 IEP
ISO
protein:increased expression:urine: RGD PMID:23552495 PMID:23019274 PMID:23085062 RGD:7244372, RGD:7245495, RGD:7245489 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment
severity
IDA
IMP
RGD PMID:17519789 PMID:22432008 RGD:1626334, RGD:9068883 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmox1 heme oxygenase 1 treatment IMP RGD PMID:21291499 RGD:10755580 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hsf1 heat shock transcription factor 1 IEP protein:increased expression:kidney (rat) RGD PMID:23102208 RGD:10402775 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 IEP RGD PMID:7569112 RGD:7242788 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hyal1 hyaluronidase 1 IEP RGD PMID:22529164 RGD:9588636 NCBI chr 8:108,250,668...108,254,519
Ensembl chr 8:108,250,667...108,260,210
JBrowse link
G Hyal2 hyaluronidase 2 IEP RGD PMID:22529164 RGD:9588636 NCBI chr 8:108,241,895...108,246,853
Ensembl chr 8:108,243,133...108,246,850
JBrowse link
G Ifng interferon gamma treatment ISO RGD PMID:28355607 RGD:14975115 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Igf1r insulin-like growth factor 1 receptor IEP mRNA: increased expression: kidney: 3 and 5 days post ischemia RGD PMID:10990448 RGD:7242905 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta treatment IMP RGD PMID:19546526 RGD:7495779 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Il10 interleukin 10 treatment IDA
ISO
RGD PMID:24079335 PMID:28664613 RGD:7364864, RGD:14975137 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il12b interleukin 12B ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il18 interleukin 18 treatment IMP RGD PMID:22089199 RGD:8655971 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1b interleukin 1 beta ameliorates IDA
ISO
RGD PMID:20030532 PMID:24920753 RGD:7175501, RGD:329845564 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO rat model treated with human protein
mouse model treated with human protein
RGD PMID:18363573 PMID:9555664 PMID:16849996 RGD:6907101, RGD:6909149, RGD:6907359 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il6 interleukin 6 ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Inhbb inhibin subunit beta B IEP protein:increased expression:serum (rat) RGD PMID:27732750 RGD:329322881 NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832
JBrowse link
G Itgb2 integrin subunit beta 2 ISO
IMP
Associated with renal transplant patients RGD PMID:20504838 PMID:11007822 RGD:6907049, RGD:6907073 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 IEP protein:decreased expression:kidney RGD PMID:21250976 RGD:7297045 NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
JBrowse link
G Kl Klotho treatment IEP
ISO
mRNA,protein:decreased expression:renal tubule: RGD PMID:16204278 PMID:16204278 RGD:10403064, RGD:10403064 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080
JBrowse link
G Kmt2a lysine methyltransferase 2A ISO protein:increased expression:kidney (mouse) RGD PMID:31570196 RGD:155888490 NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181
JBrowse link
G Lcn2 lipocalin 2 IEP
ISO
protein:increased expression:urine:
mRNA,protein:increased expression:kidney,urine
mRNA,protein:increased expression:kidney:
RGD PMID:23364806 PMID:27800610 PMID:20181666 PMID:23085062 RGD:7245469, RGD:126790572, RGD:126779563, RGD:7245489 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Lep leptin resistance IDA RGD PMID:22969992 RGD:6909133 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lgals3 galectin 3 IEP mRNA:increased expression:kidney RGD PMID:10980121 RGD:9685228 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha treatment ISO
IEP
RGD PMID:20075199 PMID:26412257 RGD:11561916, RGD:11561958 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 treatment IMP RGD PMID:23952292 RGD:10412647 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
JBrowse link
G Mc1r melanocortin 1 receptor IEP protein:decreased expression:kidney outer medulla RGD PMID:18790174 RGD:5687322 NCBI chr19:51,452,448...51,455,375
Ensembl chr19:51,453,239...51,454,192
JBrowse link
G Mir146a microRNA 146a treatment IEP RGD PMID:27760486 RGD:155882556 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
JBrowse link
G Mir320a microRNA 320a treatment IEP RGD PMID:31089916 PMID:27760486 RGD:155882543, RGD:155882556 NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473
JBrowse link
G Mir381 microRNA 381 IEP RNA:decreased expression:kidney RGD PMID:29073721 RGD:13825150 NCBI chr 6:128,740,976...128,741,036 JBrowse link
G Mir423 microRNA 423 treatment IMP RGD PMID:29137244 RGD:158014894 NCBI chr10:61,914,142...61,914,220
Ensembl chr10:61,914,133...61,914,226
JBrowse link
G Mir494 microRNA 494 ameliorates ISO RGD PMID:23160513 RGD:155883172 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793
JBrowse link
G Mpo myeloperoxidase IEP
ISO
protein:increased activity:kidney RGD PMID:22950848 PMID:18055546 RGD:6909167, RGD:7174699 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Muc1 mucin 1, cell surface associated treatment IDA RGD PMID:22019164 RGD:7245959 NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor IEP mRNA:increased expression:kidney (rat) RGD PMID:17220792 RGD:7207777 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 IEP
ISO
RGD PMID:24096033 PMID:22160772 RGD:13801197, RGD:13801199 NCBI chr 1:243,408,656...243,413,715
Ensembl chr 1:243,408,619...243,413,817
JBrowse link
G Nes nestin IEP RGD PMID:24503548 RGD:11570523 NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 treatment IEP RGD PMID:31089916 RGD:155882543 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nos2 nitric oxide synthase 2 treatment IEP RGD PMID:18408363 RGD:11040540 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 treatment IEP RGD PMID:29291552 PMID:18408363 RGD:13504682, RGD:11040540 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nox1 NADPH oxidase 1 treatment IEP RGD PMID:34244746 RGD:329955363 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236
JBrowse link
G Nppa natriuretic peptide A ISO RGD PMID:20471588 RGD:7247717 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IEP RGD PMID:21545725 RGD:11035217 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 severity ISO mRNA:increased expression:kidney RGD PMID:22343121 PMID:22343121 RGD:14700869, RGD:14700869 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase IEP RGD PMID:12531391 RGD:2317150 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
G Pax2 paired box 2 IEP mRNA, protein:increased expression:kidney RGD PMID:12444203 RGD:727468 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321
JBrowse link
G Pdgfb platelet derived growth factor subunit B IEP mRNA,protein:increased expression:tubule, S3 segment: RGD PMID:10550325 RGD:8554477 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha IEP mRNA:increased expression:kidney RGD PMID:10550325 RGD:8554477 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta IMP
IEP
mRNA:increased expression:kidney RGD PMID:12819032 PMID:10550325 RGD:1580850, RGD:8554477 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Peg10 paternally expressed 10 ISO mRNA:increased expression:kidney (mouse) RGD PMID:16778176 RGD:401851077 NCBI chr 4:32,842,441...32,855,639
Ensembl chr 4:32,848,493...32,852,621
JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel IEP protein:increased expression:kidney (rat) RGD PMID:12454224 RGD:1580868 NCBI chr14:5,237,135...5,280,455
Ensembl chr14:5,237,135...5,280,825
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha treatment IDA RGD PMID:24918615 RGD:10059636 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Ptgis prostaglandin I2 synthase ISO mRNA:increased expression:kidney (mouse) RGD PMID:30413885 RGD:401959745 NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451
JBrowse link
G Rnls renalase, FAD-dependent amine oxidase ISO mRNA,protein:decreased expression:kidney,plasma: RGD PMID:23393318 PMID:23393318 RGD:7327166, RGD:7327166 NCBI chr 1:231,037,481...231,309,855
Ensembl chr 1:231,037,486...231,309,823
JBrowse link
G Serpina1 serpin family A member 1 treatment ISO RGD PMID:28235038 RGD:14695051 NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339
JBrowse link
G Serpinc1 serpin family C member 1 severity IMP RGD PMID:26108065 PMID:26108065 RGD:11354006, RGD:11354006 NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293
JBrowse link
G Serpinc1em2Mcwi serpin family C member 1; ZFN induced mutant 2, Medical College of Wisconsin IMP RGD PMID:26108065 RGD:11354006
G Serpine1 serpin family E member 1 ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Shh sonic hedgehog signaling molecule ISO mRNA, protein:increased expression:kidney RGD PMID:24744439 RGD:12859042 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Sirt1 sirtuin 1 treatment IEP RGD PMID:22324445 RGD:9495930 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Six2 SIX homeobox 2 ISO mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr 6:8,974,859...8,981,345
Ensembl chr 6:8,967,157...8,981,193
JBrowse link
G Slc22a1 solute carrier family 22 member 1 IEP RGD PMID:21835768 RGD:7243877 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
JBrowse link
G Slc22a2 solute carrier family 22 member 2 IEP RGD PMID:21835768 RGD:7243877 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Slc34a1 solute carrier family 34 member 1 IEP protein:decreased expression:renal proximal tubule, brush border membrane (rat) RGD PMID:15775707 RGD:2311304 NCBI chr17:9,218,876...9,233,852
Ensembl chr17:9,218,876...9,233,852
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IEP RGD PMID:12819032 RGD:1580850 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Stat6 signal transducer and activator of transcription 6 severity ISO RGD PMID:12709397 RGD:7244143 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
JBrowse link
G Suz12 SUZ12 polycomb repressive complex 2 subunit ISO mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr10:64,967,035...65,012,916
Ensembl chr10:64,966,967...65,012,738
JBrowse link
G Tfpi tissue factor pathway inhibitor ISO RGD PMID:11796005 RGD:11062062 NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tlr2 toll-like receptor 2 treatment
severity
IDA
ISO
RGD PMID:23239000 PMID:11801667 PMID:20130923 PMID:22750071 PMID:23023072 RGD:7207892, RGD:7241087, RGD:7240552, RGD:7207896, RGD:7207894 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tlr4 toll-like receptor 4 treatment IDA
ISO
RGD PMID:23239000 PMID:11801667 PMID:20130923 RGD:7207892, RGD:7241087, RGD:7240552 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor ameliorates IEP
ISO
protein:increased expression:serum RGD PMID:19925291 PMID:24920753 RGD:2315112, RGD:329845564 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO mRNA:increased expression:lung RGD PMID:22728466 RGD:7245543 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 IEP protein:increased expression:kidney RGD PMID:20164827 RGD:7240507 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vwf von Willebrand factor IEP protein:increased expression:serum: RGD PMID:12684225 RGD:11080744 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539
JBrowse link
G Wt1 WT1 transcription factor ISO mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643
JBrowse link
G Xdh xanthine dehydrogenase treatment IMP associated with Diabetes Mellitus, Type 2 RGD PMID:22995295 PMID:20616412 RGD:7247637, RGD:7247695 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link
G Zfp667 zinc finger protein 667 ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chr 1:67,601,803...67,622,041
Ensembl chr 1:67,601,807...67,622,041
JBrowse link
King Denborough syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ryr1 ryanodine receptor 1 ISO ClinVar Annotator: match by term: King Denborough syndrome | ClinVar Annotator: match by term: King syndrome ClinVar
OMIM
PMID:16940 PMID:18253 PMID:18564 PMID:1510267 PMID:1639409 More... NCBI chr 1:84,292,578...84,423,824
Ensembl chr 1:84,292,578...84,423,812
JBrowse link
limb reperfusion injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpt glutamic--pyruvic transaminase treatment IEP RGD PMID:36495512 RGD:401717522 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
Liver Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing treatment IDA RGD PMID:23762489 RGD:8695935 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Adm adrenomedullin treatment IEP
ISO
mRNA,protein:increased expression:liver,plasma: RGD PMID:19212187 PMID:19212187 RGD:7364958, RGD:7364958 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Ager advanced glycosylation end product-specific receptor IEP mRNA:increased expression:liver RGD PMID:21431875 RGD:10402078 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member treatment ISO
IEP
protein:altered expression:liver (mouse)
protein:altered expression:liver (rat)
RGD PMID:30671488 PMID:29589772 RGD:15036807, RGD:14975297 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Atf6 activating transcription factor 6 ameliorates ISO RGD PMID:34144219 RGD:329812011 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atg13 autophagy related 13 ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr 3:77,647,069...77,681,028
Ensembl chr 3:77,645,790...77,681,043
JBrowse link
G Atg16l1 autophagy related 16-like 1 ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr 9:88,420,737...88,457,530
Ensembl chr 9:88,422,038...88,457,529
JBrowse link
G Atg4d autophagy related 4D, cysteine peptidase ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr 8:19,807,733...19,817,321
Ensembl chr 8:19,807,766...19,817,321
JBrowse link
G Atg7 autophagy related 7 ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Bad BCL2-associated agonist of cell death treatment IEP mRNA:increased expression:liver
associated with Non-alcoholic Fatty Liver Disease
RGD PMID:22647552 PMID:22847887 RGD:10053673, RGD:10053710 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bax BCL2 associated X, apoptosis regulator ameliorates
treatment
IEP
ISO
mRNA:increased expression:liver
associated with Non-alcoholic Fatty Liver Disease
RGD PMID:22647552 PMID:34144219 PMID:21092002 PMID:22847887 RGD:10053673, RGD:329812011, RGD:5134995, RGD:10053710 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment
ameliorates
IDA
ISO
IEP
associated with Non-alcoholic Fatty Liver Disease RGD PMID:22847887 PMID:34144219 PMID:21092002 RGD:10053710, RGD:329812011, RGD:5134995 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 treatment IEP associated with Non-alcoholic Fatty Liver Disease RGD PMID:22847887 RGD:10053710 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479
JBrowse link
G Becn1 beclin 1 ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bid BH3 interacting domain death agonist ameliorates IMP RGD PMID:17893612 RGD:408346749 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G C3 complement C3 treatment IEP RGD PMID:19854450 RGD:11040888 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G Casp12 caspase 12 treatment IEP RGD PMID:29428101 RGD:13782166 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp3 caspase 3 ameliorates ISO RGD PMID:34144219 RGD:329812011 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 treatment IEP
ISO
RGD PMID:23423194 PMID:15300206 RGD:8661760, RGD:14695087 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 treatment
ameliorates
IEP
ISO
RGD PMID:23364428 PMID:34144219 RGD:13782358, RGD:329812011 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 ameliorates
treatment
severity
IEP
ISO
mRNA, protein:increased expression:liver, serum (rat) RGD PMID:9500701 PMID:34400126 PMID:10630515 PMID:27229110 RGD:8549627, RGD:329902072, RGD:14995929, RGD:14995460 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 treatment
severity
ISO RGD PMID:28623253 PMID:28623253 RGD:14995305, RGD:14995305 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
JBrowse link
G Ccn1 cellular communication network factor 1 ameliorates ISO RGD PMID:34144219 RGD:329812011 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Ccr2 C-C motif chemokine receptor 2 severity ISO RGD PMID:27229110 RGD:14995460 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Cd14 CD14 molecule IDA RGD PMID:22564590 RGD:7183676 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd40 CD40 molecule treatment IMP RGD PMID:14741776 RGD:8547795 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cfh complement factor H treatment IEP
ISO
mRNA,protein:decreased expression:liver,plasma: RGD PMID:19212187 PMID:19212187 RGD:7364958, RGD:7364958 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838
JBrowse link
G Cs citrate synthase IDA RGD PMID:25416448 RGD:13504849 NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
JBrowse link
G Cst3 cystatin C ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 treatment
ameliorates
IDA
ISO
RGD PMID:21092002 PMID:34400126 RGD:5134995, RGD:329902072 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 treatment
ameliorates
ISO RGD PMID:18041715 PMID:34400126 RGD:27095942, RGD:329902072 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IEP mRNA:decreased expression:lung RGD PMID:19595018 RGD:2314952 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 ameliorates ISO RGD PMID:34144219 RGD:329812011 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 ameliorates ISO RGD PMID:34144219 RGD:329812011 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Elane elastase, neutrophil expressed IMP RGD PMID:10588515 RGD:10450560 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100
JBrowse link
G Epo erythropoietin treatment ISO RGD PMID:25769561 RGD:15090809 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G Epor erythropoietin receptor IEP protein:increased phosphorylation:liver: RGD PMID:25769561 RGD:15090809 NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257
JBrowse link
G F3 coagulation factor III, tissue factor treatment IMP RGD PMID:11750579 RGD:11341708 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Fadd Fas associated via death domain treatment IEP RGD PMID:23423194 RGD:8661760 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Fas Fas cell surface death receptor treatment IMP
IEP
protein:increased expression:liver RGD PMID:17235585 PMID:18561025 PMID:16222447 RGD:2290283, RGD:14700680, RGD:1600351 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand treatment IMP RGD PMID:18561025 RGD:14700680 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fga fibrinogen alpha chain IEP mRNA:increased expression:liver (rat) RGD PMID:23503399 RGD:9685021 NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528
JBrowse link
G Fn1 fibronectin 1 IDA RGD PMID:12651615 RGD:7205470 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Gpt glutamic--pyruvic transaminase treatment IEP RGD PMID:22564598 PMID:13678701 RGD:329970282, RGD:329970285 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment IDA associated with nonalcoholic fatty liver disease RGD PMID:28807209 RGD:13792730 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gstm1 glutathione S-transferase mu 1 IEP mRNA:decreased expression:lung RGD PMID:19595018 RGD:2314952 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G H2ax H2A.X variant histone treatment IEP RGD PMID:23792534 RGD:8693718 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239
JBrowse link
G Hmgb1 high mobility group box 1 treatment IMP
IEP
protein:increased oxidation:liver
mRNA, protein:increased expression, altered localization:serum, hepatocyte, cytoplasm
RGD PMID:24578610 PMID:22514737 PMID:21431875 RGD:10402068, RGD:10402175, RGD:10402078 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565
JBrowse link
G Hmox1 heme oxygenase 1 treatment IEP RGD PMID:20446775 RGD:10755725 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hp haptoglobin treatment IEP RGD PMID:17187421 PMID:21699906 RGD:1626366, RGD:11041815 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment IMP
IEP
associated with Intestinal Reperfusion Injury;protein:increased expression:liver RGD PMID:7884306 PMID:8780571 RGD:11520784, RGD:14402044 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 severity ISO RGD PMID:28938192 RGD:14985248 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma treatment IDA RGD PMID:22381173 RGD:12791280 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499
JBrowse link
G Il10 interleukin 10 treatment IDA RGD PMID:21911118 RGD:7364839 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il18 interleukin 18 treatment IEP
ISO
RGD PMID:25919765 PMID:14999688 RGD:14696667, RGD:14696668 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il18bp interleukin 18 binding protein IEP mRNA,protein:increased expression:liver RGD PMID:25919765 RGD:14696667 NCBI chr 1:156,372,923...156,374,963
Ensembl chr 1:156,372,883...156,374,963
JBrowse link
G Il1a interleukin 1 alpha treatment IEP
IDA
mRNA:increased expression:lung
protein:increased expression:serum
RGD PMID:19595018 PMID:9840148 PMID:19283466 RGD:2314952, RGD:11059517, RGD:6907377 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta ameliorates
treatment
IDA
ISO
associated with Cholestasis RGD PMID:21468628 PMID:34400126 PMID:32155285 RGD:7175318, RGD:329902072, RGD:155260323 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO
IMP
rat model treated with human protein RGD PMID:9000676 PMID:12451245 RGD:6909138, RGD:8551710 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il6 interleukin 6 treatment
ameliorates
IDA
ISO
RGD PMID:24752458 PMID:34400126 PMID:34144219 PMID:32155285 RGD:11062134, RGD:329902072, RGD:329812011, RGD:155260323 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Irf8 interferon regulatory factor 8 ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr19:48,790,581...48,812,363
Ensembl chr19:48,790,588...48,811,829
JBrowse link
G Itgam integrin subunit alpha M treatment
exacerbates
IMP
IEP
protein:increased expression:neutrophil (rat) RGD PMID:8387952 PMID:11447039 RGD:329901847, RGD:329901849 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Jak2 Janus kinase 2 treatment IDA RGD PMID:22288937 RGD:10403073 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr  X:117,173,097...117,222,090
Ensembl chr  X:117,057,606...117,260,522
JBrowse link
G Lbp lipopolysaccharide binding protein IEP mRNA, protein:increased expression:liver RGD PMID:12134092 RGD:9685192 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
Ensembl chr16:49,665,791...49,677,690
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 ameliorates
exacerbates
ISO protein:increased phosphorylation:liver (mouse) RGD PMID:30076625 PMID:30622220 RGD:155804280, RGD:155882441 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IEP protein:increased activity:liver: RGD PMID:11679968 RGD:10412680 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mfn2 mitofusin 2 treatment IEP mRNA, protein:decreased expression:liver (rat) RGD PMID:27363631 PMID:24898700 RGD:12910833, RGD:13204829 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mir145 microRNA 145 IEP mRNA:decreased expression:small intestine (rat) RGD PMID:23166305 RGD:155230822 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727
JBrowse link
G Mir155 microRNA 155 ISO RGD PMID:28640790 RGD:21079442 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mir21 microRNA 21 IEP RNA:increased expression:liver RGD PMID:29187695 RGD:41410824 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mir210 microRNA 210 treatment ISO RGD PMID:32155285 RGD:155260323 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454
JBrowse link
G Mir223 microRNA 223 ISO RNA:increased expression:liver
RNA:increased expression:serum,liver
RGD PMID:19104939 PMID:28646120 RGD:13831297, RGD:21408574 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996
JBrowse link
G Mir34a microRNA 34a IEP miRNA:increased expression:liver RGD PMID:28963950 RGD:14695005 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103
JBrowse link
G Mmp15 matrix metallopeptidase 15 IEP mRNA:increased expression:lung RGD PMID:19595018 RGD:2314952 NCBI chr19:9,663,449...9,684,943
Ensembl chr19:9,663,449...9,684,943
JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment IEP associated with Fatty Liver;mRNA, protein:decreased expression, decreased activity:liver RGD PMID:17255325 RGD:8547976 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Muc1 mucin 1, cell surface associated IEP mRNA, protein:decreased expression:bile duct RGD PMID:21775928 RGD:7364757 NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Muc17 mucin 17, cell surface associated IEP mRNA, protein:decreased expression:bile duct RGD PMID:21775928 RGD:7364757 NCBI chr12:19,527,251...19,536,924
Ensembl chr12:19,527,321...19,538,522
JBrowse link
G Muc4 mucin 4, cell surface associated IEP mRNA:decreased expression:bile duct RGD PMID:21775928 RGD:7364757 NCBI chr11:68,008,245...68,053,242 JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 ISO mRNA,protein:increased expression:liver: RGD PMID:36092961 RGD:268357360 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 treatment IEP RGD PMID:22288937 PMID:31952110 RGD:10403073, RGD:21201304 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nos3 nitric oxide synthase 3 treatment IEP RGD PMID:28966130 RGD:13450941 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Pf4 platelet factor 4 exacerbates ISO RGD PMID:25440775 RGD:329901829 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:12605111 PMID:18507760 RGD:11100021, RGD:11100046 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133
JBrowse link
G Rab10 RAB10, member RAS oncogene family ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr 6:26,267,081...26,319,739
Ensembl chr 6:26,266,859...26,320,193
JBrowse link
G Rab8b RAB8B, member RAS oncogene family ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr 8:67,458,921...67,536,466
Ensembl chr 8:67,458,923...67,536,384
JBrowse link
G Selplg selectin P ligand ameliorates IMP RGD PMID:16365457 RGD:401717523 NCBI chr12:42,796,690...42,809,908
Ensembl chr12:42,796,580...42,812,585
JBrowse link
G Serpinc1 serpin family C member 1 treatment IEP
ISO
RGD PMID:24726586 PMID:8589354 RGD:10450597, RGD:11038771 NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293
JBrowse link
G Serpine1 serpin family E member 1 IEP protein:increased activity:plasma (rat) RGD PMID:12353078 RGD:8547901 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Serping1 serpin family G member 1 treatment ISO RGD PMID:16367929 RGD:1580273 NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034
JBrowse link
G Sirt1 sirtuin 1 treatment IEP RGD PMID:24557422 RGD:9497542 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor IEP RGD PMID:19595018 RGD:2314952 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
JBrowse link
G Sod1 superoxide dismutase 1 treatment ISO human gene in a rat model RGD PMID:16555330 PMID:11779401 RGD:8655889, RGD:1581095 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod3 superoxide dismutase 3 treatment ISO human gene in a rat model RGD PMID:11779401 RGD:1581095 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Tert telomerase reverse transcriptase treatment ISO RGD PMID:19545665 RGD:11038676 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tfpi tissue factor pathway inhibitor ISO RGD PMID:9921794 RGD:11062061 NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880
JBrowse link
G Tlr2 toll-like receptor 2 treatment ISO
IEP
RGD PMID:16038046 PMID:25769561 RGD:15090805, RGD:15090809 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
G Tlr4 toll-like receptor 4 treatment
severity
IEP
ISO
mRNA:increased expression:liver
protein:increased expression:membrane raft:
RGD PMID:21431875 PMID:21693218 PMID:22797797 PMID:23395256 PMID:27064547 RGD:10402078, RGD:5685379, RGD:14697702, RGD:14697699, RGD:14697698 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor treatment IEP
IMP
ISO
protein:increased expression:serum (rat) RGD PMID:24726586 PMID:12131680 PMID:32155285 PMID:11592783 PMID:19357028 More... RGD:10450597, RGD:14995454, RGD:155260323, RGD:2325259, RGD:15039406, RGD:14995473, RGD:14995447, RGD:14985258, RGD:14985257, RGD:14696803 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A IEP protein:increased localization:mitochondrion RGD PMID:23423194 RGD:8661760 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Tradd TNFRSF1A-associated via death domain treatment IEP RGD PMID:23423194 RGD:8661760 NCBI chr19:33,136,148...33,142,714
Ensembl chr19:33,136,138...33,142,638
JBrowse link
G Ucp2 uncoupling protein 2 IEP mRNA:increased expression:liver RGD PMID:22195248 RGD:7175309 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Vegfa vascular endothelial growth factor A IEP RGD PMID:26451003 RGD:15036791 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Xdh xanthine dehydrogenase treatment IEP RGD PMID:24768926 RGD:13209011 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link
Lung Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator treatment
ameliorates
IEP
ISO
RGD PMID:23953793 PMID:34238924 RGD:10054119, RGD:153350155 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP RGD PMID:23953793 RGD:10054119 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Casp3 caspase 3 treatment IEP RGD PMID:23953793 RGD:10054119 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Col1a1 collagen type I alpha 1 chain ISO mRNA:increased expression:lung (mouse) RGD PMID:34238924 RGD:153350155 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col3a1 collagen type III alpha 1 chain ISO mRNA:increased expression:lung (mouse) RGD PMID:34238924 RGD:153350155 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Crebbp CREB binding protein ameliorates ISO RGD PMID:34238924 RGD:153350155 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
JBrowse link
G Egr1 early growth response 1 treatment IMP
IEP
RGD PMID:22878149 PMID:23232597 RGD:10395282, RGD:10395299 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Elane elastase, neutrophil expressed treatment IMP RGD PMID:17888675 RGD:10450582 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO mRNA:increased expression:lung (rat) RGD PMID:35600952 RGD:155663563 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Hmgb1 high mobility group box 1 IEP protein:increased expression:lung RGD PMID:22115333 RGD:10402095 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565
JBrowse link
G Hmox1 heme oxygenase 1 IEP protein:increased expression:lung RGD PMID:21227458 RGD:10755577 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment IEP RGD PMID:22503847 RGD:7240537 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il1b interleukin 1 beta ameliorates IDA
ISO
IEP
protein:increased expression:lung (rat) RGD PMID:23142117 PMID:34238924 PMID:23122581 RGD:7183185, RGD:153350155, RGD:7204125 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il4 interleukin 4 treatment IDA RGD PMID:24365768 RGD:10402797 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 ameliorates ISO RGD PMID:34238924 RGD:153350155 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Kras KRAS proto-oncogene, GTPase ameliorates ISO RGD PMID:34238924 RGD:153350155 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Mmp9 matrix metallopeptidase 9 IEP protein:increased activity:lung RGD PMID:18694576 RGD:5129703 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor treatment IEP RGD PMID:22503847 RGD:7240537 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nos3 nitric oxide synthase 3 IMP
ISO
mRNA:increased expression:lung (mouse) RGD PMID:20815765 PMID:25382268 RGD:4892012, RGD:11533932 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IEP RGD PMID:21781312 RGD:6771212 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 IDA
IEP
protein:increased expression:alveolar macrophage (rat) RGD PMID:21781312 PMID:16449942 RGD:6771212, RGD:11541083 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:19782612 RGD:11100035 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133
JBrowse link
G Serpine1 serpin family E member 1 treatment ISO
IDA
protein:increased expression:plasma (human) RGD PMID:17846288 PMID:11606484 RGD:8547720, RGD:11080966 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Tlr4 toll-like receptor 4 treatment IEP RGD PMID:22115333 RGD:10402095 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor ameliorates IMP
ISO
RGD PMID:17294835 PMID:34238924 RGD:4143397, RGD:153350155 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Zfp36 zinc finger protein 36 exacerbates ISO RGD PMID:34238924 RGD:153350155 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
JBrowse link
Malignant Fever term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1s calcium voltage-gated channel subunit alpha1 S ISO ClinVar Annotator: match by term: Pharmacogenic myopathy ClinVar PMID:20861472 PMID:24033266 PMID:24055113 PMID:24195946 PMID:24784157 More... NCBI chr13:47,493,949...47,564,194
Ensembl chr13:47,493,949...47,564,318
JBrowse link
G Ryr1 ryanodine receptor 1 ISO ClinVar Annotator: match by term: Pharmacogenic myopathy
ClinVar Annotator: match by term: Fulminating hyperpyrexia | ClinVar Annotator: match by term: Pharmacogenic myopathy
ClinVar PMID:12434 PMID:16940 PMID:18253 PMID:18564 PMID:1256913 More... NCBI chr 1:84,292,578...84,423,824
Ensembl chr 1:84,292,578...84,423,812
JBrowse link
malignant hyperthermia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asph aspartate-beta-hydroxylase ISO ClinVar Annotator: match by term: Exercise-induced malignant hyperthermia | ClinVar Annotator: match by term: Malignant hyperthermia of anesthesia ClinVar NCBI chr 5:22,601,581...22,814,107
Ensembl chr 5:22,603,486...22,813,876
JBrowse link
G Cacna1s calcium voltage-gated channel subunit alpha1 S susceptibility ISO DNA,protein:missense mutation:cds:p.R1086H (human)
ClinVar Annotator: match by term: Anesthesia related hyperthermia | ClinVar Annotator: match by term: Malignant hyperpyrexia | ClinVar Annotator: match by term: Malignant hyperpyrexia susceptibility type 5 | ClinVar Annotator: match by term: Malignant hyperthermia of anesthesia | ClinVar Annotator: match by term: Malignant hyperthermia susceptibility | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 1 | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 5
ClinVar Annotator: match by term: Exercise-induced malignant hyperthermia | ClinVar Annotator: match by term: Malignant hyperpyrexia | ClinVar Annotator: match by term: Malignant hyperpyrexia susceptibility type 5 | ClinVar Annotator: match by term: Malignant hyperthermia of anesthesia | ClinVar Annotator: match by term: Malignant hyperthermia susceptibility | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 1 | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 5
ClinVar Annotator: match by term: Anesthesia related hyperthermia | ClinVar Annotator: match by term: Malignant hyperpyrexia | ClinVar Annotator: match by term: Malignant hyperpyrexia susceptibility type 5 | ClinVar Annotator: match by term: Malignant hyperthermia of anesthesia | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 1 | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 5
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Malignant hyperpyrexia | ClinVar Annotator: match by term: Malignant hyperpyrexia susceptibility type 5 | ClinVar Annotator: match by term: Malignant hyperthermia | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 5
ClinVar Annotator: match by term: Hyperpyrexia, malignant | ClinVar Annotator: match by term: Malignant hyperpyrexia susceptibility type 5 | ClinVar Annotator: match by term: Malignant hyperthermia | ClinVar Annotator: match by term: Malignant hyperthermia susceptibility | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 5
OMIM
ClinVar
CTD
RGD
PMID:1982519 PMID:3037387 PMID:7650604 PMID:7847370 PMID:7897626 More... RGD:1300373 NCBI chr13:47,493,949...47,564,194
Ensembl chr13:47,493,949...47,564,318
JBrowse link
G Cacng1 calcium voltage-gated channel auxiliary subunit gamma 1 ISO RGD PMID:8395940 RGD:734675 NCBI chr10:92,652,924...92,665,612
Ensembl chr10:92,652,614...92,665,783
JBrowse link
G Casq1 calsequestrin 1 ISO RGD PMID:19237502 RGD:329813080 NCBI chr13:84,670,648...84,680,339
Ensembl chr13:84,670,649...84,680,339
JBrowse link
G Ryr1 ryanodine receptor 1 treatment ISO
ISS
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Anesthesia related hyperthermia | ClinVar Annotator: match by term: Malignant hyperpyrexia | ClinVar Annotator: match by term: Malignant hyperpyrexia susceptibility type 5 | ClinVar Annotator: match by term: Malignant hyperthermia of anesthesia | ClinVar Annotator: match by term: Malignant hyperthermia susceptibility | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 1 | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 5
ClinVar Annotator: match by term: Anesthesia related hyperthermia | ClinVar Annotator: match by term: Malignant hyperpyrexia | ClinVar Annotator: match by term: Malignant hyperthermia of anesthesia | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 1 | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 5
ClinVar Annotator: match by term: Anesthesia related hyperthermia | ClinVar Annotator: match by term: Malignant hyperpyrexia | ClinVar Annotator: match by term: Malignant hyperpyrexia susceptibility type 5 | ClinVar Annotator: match by term: Malignant hyperthermia of anesthesia | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 1 | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 5
ClinVar Annotator: match by term: Anesthesia related hyperthermia | ClinVar Annotator: match by term: Exercise-induced malignant hyperthermia | ClinVar Annotator: match by term: Malignant hyperpyrexia | ClinVar Annotator: match by term: Malignant hyperthermia of anesthesia | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 1 | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 5
ClinVar Annotator: match by term: Anesthesia related hyperthermia | ClinVar Annotator: match by term: Hyperpyrexia, malignant | ClinVar Annotator: match by term: Malignant hyperpyrexia | ClinVar Annotator: match by term: Malignant hyperthermia | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 1
ClinVar Annotator: match by term: Anesthesia related hyperthermia | ClinVar Annotator: match by term: Exercise-induced malignant hyperthermia | ClinVar Annotator: match by term: Hyperpyrexia, malignant | ClinVar Annotator: match by term: Malignant hyperpyrexia | ClinVar Annotator: match by term: Malignant hyperthermia | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 1 | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 5
ClinVar Annotator: match by term: Anesthesia related hyperthermia | ClinVar Annotator: match by term: Malignant hyperpyrexia | ClinVar Annotator: match by term: Malignant hyperthermia | ClinVar Annotator: match by term: Malignant hyperthermia susceptibility | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 1
ClinVar Annotator: match by term: Anesthesia related hyperthermia | ClinVar Annotator: match by term: Hyperpyrexia, malignant | ClinVar Annotator: match by term: Malignant hyperpyrexia | ClinVar Annotator: match by term: Malignant hyperthermia | ClinVar Annotator: match by term: Malignant hyperthermia susceptibility | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 1
CTD
OMIM
ClinVar
MouseDO
RGD
PMID:12434 PMID:16940 PMID:18253 PMID:18564 PMID:1256913 More... RGD:329812001, RGD:329812000, RGD:329811997 NCBI chr 1:84,292,578...84,423,824
Ensembl chr 1:84,292,578...84,423,812
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 ISO ClinVar Annotator: match by term: Malignant hyperthermia of anesthesia ClinVar PMID:25741868 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
JBrowse link
Multiple Pterygium Syndrome, Lethal Type term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpg alkaline phosphatase, germ cell ISO ClinVar Annotator: match by term: Lethal multiple pterygium syndrome ClinVar PMID:28492532 NCBI chr 9:87,748,721...87,761,500
Ensembl chr 9:87,753,648...87,757,836
JBrowse link
G Alpi alkaline phosphatase, intestinal ISO ClinVar Annotator: match by term: Lethal multiple pterygium syndrome ClinVar PMID:28492532 NCBI chr 9:87,773,411...87,776,877
Ensembl chr 9:87,773,411...87,776,877
JBrowse link
G Alpp alkaline phosphatase, placental ISO ClinVar Annotator: match by term: Lethal multiple pterygium syndrome ClinVar PMID:28492532 NCBI chr 9:87,765,846...87,768,606
Ensembl chr 9:87,765,860...87,768,606
JBrowse link
G Chrna1 cholinergic receptor nicotinic alpha 1 subunit ISO ClinVar Annotator: match by term: Lethal multiple pterygium syndrome OMIM
ClinVar
PMID:6287911 PMID:7619526 PMID:7863154 PMID:9158151 PMID:9221765 More... NCBI chr 3:58,454,763...58,469,832
Ensembl chr 3:58,454,744...58,469,840
JBrowse link
G Chrnd cholinergic receptor nicotinic delta subunit ISO ClinVar Annotator: match by term: Lethal multiple pterygium syndrome OMIM
ClinVar
PMID:8872460 PMID:9536098 PMID:11435464 PMID:11782989 PMID:16199547 More... NCBI chr 9:87,862,417...87,870,833
Ensembl chr 9:87,862,407...87,870,833
JBrowse link
G Chrng cholinergic receptor nicotinic gamma subunit ISO ClinVar Annotator: match by term: Lethal multiple pterygium syndrome OMIM
ClinVar
PMID:16826520 PMID:16826531 PMID:22167768 PMID:24038971 PMID:24254455 More... NCBI chr 9:87,878,085...87,884,193
Ensembl chr 9:87,878,085...87,914,482
JBrowse link
G Dis3l2 DIS3-like 3'-5' exoribonuclease 2 ISO ClinVar Annotator: match by term: Lethal multiple pterygium syndrome ClinVar PMID:28492532 NCBI chr 9:87,355,409...87,736,616
Ensembl chr 9:87,356,457...87,736,616
JBrowse link
G Ecel1 endothelin converting enzyme-like 1 ISO ClinVar Annotator: match by term: Lethal multiple pterygium syndrome ClinVar PMID:28492532 NCBI chr 9:87,819,516...87,829,154
Ensembl chr 9:87,816,718...87,826,675
JBrowse link
G Prss56 serine protease 56 ISO ClinVar Annotator: match by term: Lethal multiple pterygium syndrome ClinVar PMID:28492532 NCBI chr 9:87,842,806...87,859,978
Ensembl chr 9:87,854,805...87,859,978
JBrowse link
Myocardial Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 ISO RGD PMID:18316485 RGD:2301903 NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510
JBrowse link
G Acvr2b activin A receptor type 2B treatment ISO human construct in mouse model
mRNA, protein:decreased expression:heart (mouse)
RGD PMID:30765322 PMID:30765322 RGD:329849112, RGD:329849112 NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:119,138,812...119,170,458
JBrowse link
G Ada adenosine deaminase IDA protein:increased expression RGD PMID:16641873 RGD:1624305 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: therapeutic CTD PMID:16155579 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Adrb1 adrenoceptor beta 1 IMP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:10900253 PMID:17201736 RGD:5129149 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Adrb2 adrenoceptor beta 2 IDA RGD PMID:16269402 RGD:1598746 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Ager advanced glycosylation end product-specific receptor IEP protein:increased expression:heart (rat) RGD PMID:16505177 RGD:1625342 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Agl amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase IMP RGD PMID:9281456 RGD:1598779 NCBI chr 2:204,705,053...204,760,966
Ensembl chr 2:204,705,053...204,760,828
JBrowse link
G Agt angiotensinogen ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:2535056 PMID:19166939 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtr1a angiotensin II receptor, type 1a IEP protein:increased expression:myocardium RGD PMID:21078800 RGD:5129194 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Ahr aryl hydrocarbon receptor treatment IMP RGD PMID:35788946 RGD:401793705 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 IEP
ISO
protein:decreased expression:mitochondrion: RGD PMID:23685150 PMID:23685150 RGD:10053560, RGD:10053560 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Akt1 AKT serine/threonine kinase 1 IDA protein:increased phosphorylation:heart left ventricle RGD PMID:20217242 RGD:5509104 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt2 AKT serine/threonine kinase 2 IDA RGD PMID:16418318 RGD:2313347 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:9572063 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member IDA RGD PMID:23468836 RGD:7241598 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Alox5 arachidonate 5-lipoxygenase IMP RGD PMID:20011686 RGD:2317527 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Angpt2 angiopoietin 2 IEP mRNA, protein:increased expression:myocardium (rat) RGD PMID:12737621 RGD:1601505 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804
JBrowse link
G Ank1 ankyrin 1 IDA RGD PMID:9378703 RGD:1599110 NCBI chr16:68,876,294...69,054,963
Ensembl chr16:68,877,504...69,054,759
JBrowse link
G Ank2 ankyrin 2 IDA RGD PMID:9378703 RGD:1599110 NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923
JBrowse link
G Ankrd1 ankyrin repeat domain 1 IEP protein:decreased expression:myocardium RGD PMID:19299913 RGD:5133278 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
JBrowse link
G Anxa1 annexin A1 treatment IEP
ISO
protein:increased expression:heart, leukocyte RGD PMID:11641252 PMID:22924634 PMID:22924634 RGD:2306910, RGD:7421655, RGD:7421655 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 IEP protein:altered localization:cytoplasm RGD PMID:17602955 RGD:2315672 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
JBrowse link
G Arrb2 arrestin, beta 2 IEP RGD PMID:29016703 RGD:13506827 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Atf3 activating transcription factor 3 IEP RGD PMID:11485922 RGD:7327201 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 ISO CTD Direct Evidence: therapeutic CTD PMID:29702141 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 IMP RGD PMID:17630344 RGD:13782075 NCBI chr 1:181,026,606...181,044,859
Ensembl chr 1:181,026,608...181,044,838
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 treatment ISO
IEP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:10734148 PMID:28637456 RGD:13782080 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
JBrowse link
G Atp5f1d ATP synthase F1 subunit delta treatment IEP protein:decreased expression:myocardium (rat) RGD PMID:26109848 PMID:25305180 RGD:13792666, RGD:13792676 NCBI chr 7:9,560,604...9,565,919
Ensembl chr 7:9,560,608...9,565,929
JBrowse link
G Bad BCL2-associated agonist of cell death treatment IEP
IDA
protein:increased expression, decreased serine phosphorylation:heart RGD PMID:15339931 PMID:23364609 RGD:2292700, RGD:10053674 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:20026869 PMID:21223820 PMID:25547710 PMID:31583047 RGD:10054103, RGD:13782178, RGD:155230831 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP
IDA
RGD PMID:16289365 PMID:23364609 PMID:20821058 PMID:31583047 RGD:1599484, RGD:10053674, RGD:11561911, RGD:155230831 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 treatment IDA RGD PMID:12668130 RGD:11035287 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479
JBrowse link
G Becn1 beclin 1 treatment IDA
ISO
RGD PMID:20821058 PMID:20812860 RGD:11561911, RGD:11561944 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bid BH3 interacting domain death agonist IDA
IEP
protein:increased cleavage:heart: RGD PMID:19940077 PMID:11934844 RGD:2317561, RGD:13782263 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Blk BLK proto-oncogene, Src family tyrosine kinase IEP mRNA:increased expression:left ventricle (rat) RGD PMID:17562528 RGD:1642307 NCBI chr15:37,626,746...37,665,053
Ensembl chr15:37,627,039...37,665,031
JBrowse link
G Bnip3 BCL2 interacting protein 3 treatment IMP
IEP
protein:decreased expression:myocardium (human) RGD PMID:16645637 PMID:28661226 RGD:11561983, RGD:155260328 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Brd4 bromodomain containing 4 ISO mRNA,protein:increased expression:heart RGD PMID:33982231 RGD:155883171 NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539
JBrowse link
G Btg2 BTG anti-proliferation factor 2 IEP mRNA:increased expression:heart RGD PMID:12909328 RGD:2289075 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G C3 complement C3 IEP protein:increased expression:myocardium RGD PMID:11560858 RGD:1582136 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G C5 complement C5 treatment IDA
IMP
RGD PMID:9631876 PMID:23067403 RGD:1600666, RGD:7411626 NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994
JBrowse link
G Casp1 caspase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14998631 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp12 caspase 12 treatment IEP
ISO
protein:increased activity:myocardium
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:14998631 PMID:19406177 PMID:25547710 RGD:2311458, RGD:13782178 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp3 caspase 3 treatment
ameliorates
IMP
ISO
IEP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:14998631 PMID:18470603 PMID:29538428 PMID:30259997 RGD:2293314, RGD:13782276, RGD:329337366 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 treatment ISO
IEP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:14998631 PMID:29538428 RGD:13782276 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 ISO
IEP
CTD Direct Evidence: marker/mechanism
protein:increased activity:cardiomyocyte
CTD
RGD
PMID:14998631 PMID:11934844 RGD:13782263 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 ameliorates
treatment
ISO
IEP
CTD Direct Evidence: marker/mechanism
protein:increased activity:cardiomyocyte,endothelial cell
CTD
RGD
PMID:14998631 PMID:30259997 PMID:29538428 PMID:11934844 RGD:329337366, RGD:13782276, RGD:13782263 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Casr calcium-sensing receptor IEP protein:increased expression:ventricular myocardium (rat) RGD PMID:21766206 RGD:7205698 NCBI chr11:64,235,251...64,304,811
Ensembl chr11:64,235,251...64,304,811
JBrowse link
G Cast calpastatin ameliorates IEP
ISO
human transcript overexpression in rat model RGD PMID:12482022 PMID:14519437 RGD:5683872, RGD:405101692 NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659
JBrowse link
G Cat catalase IEP
ISO
CTD Direct Evidence: therapeutic CTD
RGD
PMID:21600015 PMID:11510883 RGD:1581149 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cbl Cbl proto-oncogene severity ISO RGD PMID:24583314 RGD:11251947 NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP
ISO
mRNA:increased expression:heart (rat)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:12087064 PMID:10908159 RGD:8549625 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO protein:decreased expression:monocyte: RGD PMID:15786508 RGD:4892017 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 treatment ISO
IEP
protein:decreased expression:blood, monocyte (human) RGD PMID:15786508 PMID:23456481 RGD:4892017, RGD:8552227 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator treatment IEP RGD PMID:18466417 RGD:11341714 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Cnr1 cannabinoid receptor 1 IMP RGD PMID:18771032 RGD:2316217 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Cnr2 cannabinoid receptor 2 IMP RGD PMID:17950273 RGD:2316224 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
JBrowse link
G Cobll1 cordon-bleu WH2 repeat protein-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34355838 NCBI chr 3:49,753,260...49,915,168
Ensembl chr 3:49,753,262...49,915,194
JBrowse link
G Crebbp CREB binding protein treatment IEP RGD PMID:24338162 RGD:153352322 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
JBrowse link
G Crp C-reactive protein IEP protein:increased expression:serum RGD PMID:21122204 RGD:5128547 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO protein:decreased expression:blood, monocyte RGD PMID:15786508 RGD:4892017 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 IMP RGD PMID:11342480 RGD:5135269 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 IMP RGD PMID:11342480 RGD:5135269 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 IMP RGD PMID:11342480 RGD:5135269 NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093
JBrowse link
G Cybb cytochrome b-245 beta chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:19207477 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:14998631 NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387
JBrowse link
G Dnm1l dynamin 1-like ameliorates ISO RGD PMID:30259997 RGD:329337366 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Ece1 endothelin converting enzyme 1 IMP
IEP
RGD PMID:18586023 PMID:12193087 RGD:4892580, RGD:7244160 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371
JBrowse link
G Edn1 endothelin 1 IEP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:15642760 PMID:16700825 PMID:18586023 RGD:4892580 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ednra endothelin receptor type A IMP RGD PMID:18586023 RGD:4892580 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Ednrb endothelin receptor type B IMP RGD PMID:21048781 RGD:4892332 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 susceptibility ISO RGD PMID:20185832 RGD:11251775 NCBI chr19:52,867,900...52,907,308
Ensembl chr19:52,869,486...52,907,777
JBrowse link
G Ephx2 epoxide hydrolase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19834332 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Esr1 estrogen receptor 1 IMP RGD PMID:18314151 RGD:4892299 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 ISO RGD PMID:18656630 RGD:5508820 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Fadd Fas associated via death domain treatment ISO
IEP
RGD PMID:26038570 PMID:26948086 RGD:11341801, RGD:13792504 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Fas Fas cell surface death receptor treatment IDA RGD PMID:21316771 RGD:8686424 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fis1 fission, mitochondrial 1 ameliorates ISO RGD PMID:30259997 RGD:329337366 NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase treatment IEP RGD PMID:27129213 RGD:11574725 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gcg glucagon treatment ISO RGD PMID:24125539 RGD:10402369 NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929
JBrowse link
G Gdf11 growth differentiation factor 11 ISO mRNA, protein:decreased expression:heart (mouse) RGD PMID:30765322 RGD:329849112 NCBI chr 7:1,311,732...1,325,211
Ensembl chr 7:1,311,732...1,320,725
JBrowse link
G Gja1 gap junction protein, alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17445419 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Glrx glutaredoxin IEP mRNA:decreased expression:heart: RGD PMID:18163565 RGD:2306160 NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
JBrowse link
G Gpx3 glutathione peroxidase 3 ISO RGD PMID:11043918 RGD:401827843 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 treatment
susceptibility
severity
IMP
ISO
IDA
associated with Diabetes Mellitus, Experimental
associated with Hypertension
protein:increased expression:heart, mitochondrion (mouse)
RGD PMID:27865836 PMID:27601479 PMID:27296507 PMID:24170934 PMID:23467820 RGD:13513990, RGD:13513993, RGD:13513995, RGD:13792704, RGD:13792779 NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment IDA
IEP
RGD PMID:20217242 PMID:26918336 PMID:29978610 RGD:5509104, RGD:13792772, RGD:13792725 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsr glutathione-disulfide reductase treatment IEP RGD PMID:24769323 RGD:10401892 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G H19 H19 imprinted maternally expressed transcript ameliorates ISO RGD PMID:31284127 RGD:158013771 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134
JBrowse link
G H2ax H2A.X variant histone treatment IDA RGD PMID:23108649 RGD:8693739 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239
JBrowse link
G Hdac3 histone deacetylase 3 ameliorates ISO RGD PMID:33982231 RGD:155883171 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment IEP
ISO
IDA
mRNA:increased expression:heart
CTD Direct Evidence: marker/mechanism
protein:increased expression:myocardium
CTD
RGD
PMID:18549825 PMID:22050707 PMID:12189448 PMID:20170615 PMID:19727523 RGD:1626327, RGD:9068872, RGD:5147885 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmgb1 high mobility group box 1 treatment IEP
ISO
IDA
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:21113057 PMID:23531454 PMID:19540007 RGD:10402066, RGD:10402170 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565
JBrowse link
G Hmox1 heme oxygenase 1 treatment IDA
ISO
IEP
RGD PMID:12709584 PMID:23921302 PMID:22179023 RGD:1598392, RGD:10755585, RGD:10755573 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hrh2 histamine receptor H 2 susceptibility ISO RGD PMID:23467745 RGD:9685524 NCBI chr17:10,366,004...10,407,791
Ensembl chr17:10,368,298...10,407,631
JBrowse link
G Hrh3 histamine receptor H3 IDA RGD PMID:15076218 RGD:1626433 NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642
JBrowse link
G Hsf1 heat shock transcription factor 1 ISO RGD PMID:22426029 RGD:10402789 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A treatment IEP RGD PMID:20501665 RGD:10003160 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 treatment IEP RGD PMID:24129401 PMID:25547710 RGD:11354962, RGD:13782178 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Htra2 HtrA serine peptidase 2 ISO protein:increased expression:myocardium, cytosol (mouse) RGD PMID:15611365 RGD:5688376 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095
JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP
ISO
protein:increased expression:heart (rat)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:12087064 PMID:20851484 RGD:4145348 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il10 interleukin 10 treatment IEP
IDA
protein:increased expression:plasma RGD PMID:19275881 PMID:23840272 RGD:2311056, RGD:7365001 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il17a interleukin 17A treatment IMP RGD PMID:22030025 RGD:9068944 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il18 interleukin 18 ISO
IDA
RGD PMID:19164288 PMID:19805173 RGD:4889578, RGD:4889400 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il18bp interleukin 18 binding protein ISO mRNA:increased expression:heart RGD PMID:19164288 PMID:19805173 RGD:4889578, RGD:4889400 NCBI chr 1:156,372,923...156,374,963
Ensembl chr 1:156,372,883...156,374,963
JBrowse link
G Il18rap interleukin 18 receptor accessory protein ISO RGD PMID:19164288 RGD:4889578 NCBI chr 9:42,768,112...42,800,964
Ensembl chr 9:42,768,220...42,800,959
JBrowse link
G Il1a interleukin 1 alpha treatment ISO
IEP
RGD PMID:8576926 PMID:7622355 RGD:7794741, RGD:7794764 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta treatment IEP mRNA:increased expression:heart RGD PMID:17134725 PMID:31583047 RGD:1626628, RGD:155230831 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rl2 interleukin 1 receptor-like 2 IMP compared to Wild Type in cardiopulmonary bypass model RGD PMID:32048631 RGD:126925167 NCBI chr 9:42,591,658...42,639,351
Ensembl chr 9:42,591,934...42,636,667
JBrowse link
G Il1rl2tm1(Myh6-cre)Mhzh interleukin 1 receptor-like 2; tm1 (Myh6-cre), Mhzh IMP compared to Wild Type in cardiopulmonary bypass model RGD PMID:32048631 RGD:126925167
G Il1rn interleukin 1 receptor antagonist ISO rat model treated with human protein RGD PMID:22649318 RGD:7174360 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il36rn interleukin 36 receptor antagonist IMP RGD PMID:32048631 RGD:126925167 NCBI chr 3:7,044,419...7,051,016
Ensembl chr 3:7,044,406...7,051,016
JBrowse link
G Il36rntm1(Myh6-cre)Mhzh interleukin 36 receptor antagonist; tm1, Mhzh IMP RGD PMID:32048631 RGD:126925167
G Il6 interleukin 6 treatment IDA
IEP
RGD PMID:27087891 PMID:31583047 RGD:11062149, RGD:155230831 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il6r interleukin 6 receptor ISO RGD PMID:16056242 RGD:1625435 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Inhba inhibin subunit beta A ISO mRNA, protein:increased expression:heart (mouse) RGD PMID:30765322 RGD:329849112 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 IEP protein:increased activity:ventricle myocardium (rat) RGD PMID:15793310 RGD:1579809 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521
JBrowse link
G Irf9 interferon regulatory factor 9 exacerbates
ameliorates
ISO protein:increased expression:left ventricular free wall RGD PMID:25150882 PMID:25150882 PMID:25150882 RGD:125093742, RGD:125093742, RGD:125093742 NCBI chr15:29,095,474...29,101,924
Ensembl chr15:29,095,789...29,101,236
JBrowse link
G Jak2 Janus kinase 2 treatment IMP associated with Diabetes Mellitus, Experimental RGD PMID:23796350 PMID:23747931 RGD:8694332, RGD:10403071 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 ISO RGD PMID:17906066 RGD:7297046 NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 IDA RGD PMID:12234964 RGD:729109 NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603
JBrowse link
G Klrk1 killer cell lectin like receptor K1 treatment IMP RGD PMID:23953572 RGD:9685183 NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459
JBrowse link
G Kng1 kininogen 1 ISO CTD Direct Evidence: therapeutic CTD PMID:2535056 PMID:7856280 NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555
JBrowse link
G Lep leptin IEP RGD PMID:21122204 RGD:5128547 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lepr leptin receptor IEP mRNA:decreased expression:heart
mRNA:altered expression:heart
RGD PMID:15284063 PMID:17134725 RGD:5129123, RGD:1626628 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Lum lumican IDA RGD PMID:11348051 RGD:1582122 NCBI chr 7:32,358,990...32,365,794
Ensembl chr 7:32,358,614...32,365,793
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha treatment IEP
ISO
protein:increased expression:heart RGD PMID:20821058 PMID:20812860 RGD:11561911, RGD:11561944 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 ISO RGD PMID:14749328 PMID:15492008 RGD:7495840, RGD:1582277 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 treatment IEP RGD PMID:31583047 RGD:155230831 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
JBrowse link
G Mapk1 mitogen activated protein kinase 1 treatment IDA RGD PMID:15653762 PMID:25345742 RGD:1582282, RGD:13800900 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 ISO RGD PMID:14749328 RGD:7495840 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 treatment IEP
IDA
RGD PMID:29741915 PMID:25345742 PMID:28814571 RGD:13800564, RGD:13800900, RGD:13800874 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 treatment IDA
IEP
RGD PMID:15309413 PMID:31583047 PMID:12883833 RGD:1582311, RGD:155230831, RGD:1582312 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mb myoglobin ISO
IDA
RGD PMID:15132981 PMID:11972171 RGD:1582385, RGD:1582431 NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383
JBrowse link
G Mbl1 mannose binding lectin 1 IDA
IMP
ISO
RGD PMID:11560858 PMID:20216929 PMID:15972690 RGD:1582136, RGD:4889154, RGD:1582131 NCBI chr16:17,029,146...17,035,187
Ensembl chr16:17,029,118...17,035,174
JBrowse link
G Mbl2 mannose binding lectin 2 treatment ISO RGD PMID:25482922 RGD:11530049 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Mdm2 MDM2 proto-oncogene IEP protein:increased serine phosphorylation:heart ventricle (rat) RGD PMID:14644432 RGD:2317401 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mfn2 mitofusin 2 treatment IEP RGD PMID:24721408 RGD:13204835 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mir1 microRNA 1 treatment IMP RGD PMID:29741915 RGD:13800564 NCBI chr18:1,887,537...1,887,623 JBrowse link
G Mir10a microRNA 10a ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr10:81,283,171...81,283,280
Ensembl chr10:81,283,171...81,283,280
JBrowse link
G Mir10b microRNA 10b ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 3:59,628,438...59,628,546
Ensembl chr 3:59,628,438...59,628,546
JBrowse link
G Mir126a microRNA 126a ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 3:9,415,063...9,415,180
Ensembl chr 3:9,415,063...9,415,180
JBrowse link
G Mir134 microRNA 134 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 6:128,748,908...128,748,980 JBrowse link
G Mir137 microRNA 137 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 2:206,480,881...206,480,982
Ensembl chr 2:206,480,884...206,480,985
JBrowse link
G Mir140 microRNA 140 exacerbates ISO miRNA:increased expression:heart, endothelial cells (mouse) RGD PMID:30259997 PMID:31792649 RGD:329337366, RGD:329337374 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675
JBrowse link
G Mir142 microRNA 142 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr10:72,557,864...72,557,950
Ensembl chr10:72,557,857...72,557,967
JBrowse link
G Mir145 microRNA 145 treatment IEP RNA:decreased expression:heart RGD PMID:31583047 PMID:33658472 RGD:155230831, RGD:329955358 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727
JBrowse link
G Mir146b microRNA 146b IEP miRNA:increased expression:heart (rat) RGD PMID:19380620 RGD:155882541 NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:245,203,438...245,203,525
JBrowse link
G Mir181c microRNA 181c ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr19:23,983,523...23,983,628
Ensembl chr19:23,983,523...23,983,628
JBrowse link
G Mir183 microRNA 183 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 4:58,788,614...58,788,723
Ensembl chr 4:58,788,614...58,788,723
JBrowse link
G Mir186 microRNA 186 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 2:246,582,806...246,582,891
Ensembl chr 2:246,582,806...246,582,891
JBrowse link
G Mir188 microRNA 188 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr  X:15,247,715...15,247,794
Ensembl chr  X:15,247,715...15,247,794
JBrowse link
G Mir193a microRNA 193a ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr10:64,672,343...64,672,454
Ensembl chr10:64,672,343...64,672,454
JBrowse link
G Mir196b microRNA 196b ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 4:81,330,487...81,330,571
Ensembl chr 4:81,330,487...81,330,571
JBrowse link
G Mir206 microRNA 206 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 9:23,094,249...23,094,332
Ensembl chr 9:23,094,249...23,094,332
JBrowse link
G Mir20b microRNA 20b ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr  X:132,422,211...132,422,282
Ensembl chr  X:132,422,211...132,422,282
JBrowse link
G Mir21 microRNA 21 exacerbates ISO
IEP
CTD Direct Evidence: marker/mechanism
miRNA:increased expression:heart (rat)
CTD
RGD
PMID:22050707 PMID:19380620 PMID:24825878 RGD:155882541, RGD:41404665 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mir210 microRNA 210 sexual_dimorphism IEP
ISO
miRNA:increased expression:myocardium (human) RGD PMID:28661226 PMID:35296158 RGD:155260328, RGD:155663666 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454
JBrowse link
G Mir222 microRNA 222 ameliorates ISO RGD PMID:25863248 RGD:152025190 NCBI chr  X:3,428,904...3,429,006
Ensembl chr  X:3,428,904...3,429,006
JBrowse link
G Mir23b microRNA 23b ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr17:1,813,667...1,813,763
Ensembl chr17:1,813,667...1,813,763
JBrowse link
G Mir26a microRNA 26a treatment IEP RGD PMID:29978610 RGD:13792725 NCBI chr 8:118,755,289...118,755,378
Ensembl chr 8:118,755,289...118,755,378
JBrowse link
G Mir27a microRNA 27a ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917
JBrowse link
G Mir27b microRNA 27b ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529
JBrowse link
G Mir28 microRNA 28 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr11:75,975,523...75,975,608
Ensembl chr11:75,975,523...75,975,608
JBrowse link
G Mir296 microRNA 296 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 3:163,051,838...163,051,915
Ensembl chr 3:163,051,838...163,051,915
JBrowse link
G Mir301b microRNA 301b ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr11:83,879,816...83,879,893
Ensembl chr11:83,879,816...83,879,893
JBrowse link
G Mir30a microRNA 30a treatment IEP RGD PMID:25137026 RGD:35673319 NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670
JBrowse link
G Mir30c1 microRNA 30c-1 ISO CTD Direct Evidence: therapeutic CTD PMID:34217758 NCBI chr 5:134,349,237...134,349,325
Ensembl chr 5:134,349,237...134,349,325
JBrowse link
G Mir320a microRNA 320a treatment
ameliorates
IMP
ISO
RGD PMID:27175593 PMID:25268616 PMID:30840298 PMID:19380620 RGD:155882540, RGD:155882578, RGD:155882546, RGD:155882541 NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473
JBrowse link
G Mir330 microRNA 330 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 1:78,833,178...78,833,274
Ensembl chr 1:78,833,178...78,833,274
JBrowse link
G Mir331 microRNA 331 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 7:28,527,390...28,527,485
Ensembl chr 7:28,527,390...28,527,485
JBrowse link
G Mir337 microRNA 337 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 6:128,538,903...128,538,999
Ensembl chr 6:128,538,902...128,538,998
JBrowse link
G Mir346 microRNA 346 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr16:10,218,118...10,218,215
Ensembl chr16:10,218,118...10,218,215
JBrowse link
G Mir34c microRNA 34c ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 8:51,409,726...51,409,802
Ensembl chr 8:51,409,726...51,409,802
JBrowse link
G Mir361 microRNA 361 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr  X:78,246,206...78,246,275
Ensembl chr  X:78,246,206...78,246,275
JBrowse link
G Mir375 microRNA 375 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 9:76,457,911...76,457,985
Ensembl chr 9:76,457,911...76,457,985
JBrowse link
G Mir411 microRNA 411 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 6:128,723,189...128,723,264
Ensembl chr 6:128,723,184...128,723,279
JBrowse link
G Mir429 microRNA 429 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 5:166,647,459...166,647,543
Ensembl chr 5:166,647,459...166,647,543
JBrowse link
G Mir433 microRNA 433 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 6:128,545,119...128,545,211
Ensembl chr 6:128,545,112...128,545,217
JBrowse link
G Mir451a microRNA 451a ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr10:62,961,520...62,961,591
Ensembl chr10:62,961,520...62,961,591
JBrowse link
G Mir494 microRNA 494 ameliorates ISO RGD PMID:33982231 PMID:20837890 PMID:20837890 RGD:155883171, RGD:155883174, RGD:155883174 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793
JBrowse link
G Mir500 microRNA 500 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr  X:15,258,778...15,258,857
Ensembl chr  X:15,258,768...15,258,859
JBrowse link
G Mir503 microRNA 503 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr  X:132,806,303...132,806,373
Ensembl chr  X:132,806,303...132,806,373
JBrowse link
G Mir532 microRNA 532 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr  X:15,247,315...15,247,393
Ensembl chr  X:15,247,315...15,247,393
JBrowse link
G Mir542 microRNA 542 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr  X:132,802,623...132,802,701
Ensembl chr  X:132,802,623...132,802,701
JBrowse link
G Mir582 microRNA 582 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 2:40,928,571...40,928,651
Ensembl chr 2:40,928,571...40,928,651
JBrowse link
G Mir598 microRNA 598 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr15:37,962,692...37,962,770
Ensembl chr15:37,962,692...37,962,771
JBrowse link
G Mir743a microRNA 743a EXP CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr  X:145,402,692...145,402,767
Ensembl chr  X:145,402,692...145,402,767
JBrowse link
G Mirlet7i microRNA let-7i ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 7:58,642,485...58,642,569
Ensembl chr 7:58,642,480...58,642,571
JBrowse link
G Mki67 marker of proliferation Ki-67 IDA RGD PMID:22405128 RGD:6483543 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO
IEP
RGD PMID:12892382 PMID:17996137 RGD:1582539, RGD:7207397 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp2 matrix metallopeptidase 2 treatment ISO
IEP
RGD PMID:16699069 PMID:23889688 RGD:1582614, RGD:8657084 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mstn myostatin ISO mRNA, protein:increased expression:heart (mouse) RGD PMID:30765322 RGD:329849112 NCBI chr 9:48,452,533...48,458,933
Ensembl chr 9:48,452,533...48,458,933
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor IDA RGD PMID:14962484 RGD:1302746 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Ncl nucleolin IEP protein:decreased expression:heart RGD PMID:23594402 RGD:9686384 NCBI chr 9:86,999,588...87,008,112
Ensembl chr 9:86,998,019...87,008,136
JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 treatment IDA RGD PMID:21700931 RGD:13801200 NCBI chr 9:64,546,430...64,579,751
Ensembl chr 9:64,546,225...64,579,893
JBrowse link
G Nfe2l1 NFE2 like bZIP transcription factor 1 treatment IEP RGD PMID:20501665 RGD:10003160 NCBI chr10:81,796,055...81,812,926
Ensembl chr10:81,800,366...81,832,318
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 ISO RGD PMID:24915518 RGD:10412738 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha treatment IDA RGD PMID:19304943 RGD:10413871 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos2 nitric oxide synthase 2 IEP
ISO
mRNA:decreased expression:heart (rat)
CTD Direct Evidence: marker/mechanism|therapeutic
CTD
RGD
PMID:12003803 PMID:12087064 PMID:14990356 PMID:19207477 PMID:20828608 More... RGD:5509098 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 treatment IEP
IDA
ISO
IMP
CTD Direct Evidence: therapeutic CTD
RGD
PMID:12354446 PMID:20828747 PMID:29274587 PMID:29299201 PMID:18390819 RGD:4891991, RGD:13504684, RGD:13503347, RGD:2292091 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nox1 NADPH oxidase 1 IEP mRNA:increased expression:heart RGD PMID:33658472 RGD:329955358 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236
JBrowse link
G Nppb natriuretic peptide B IDA RGD PMID:21168723 RGD:5685663 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Nppc natriuretic peptide C IDA RGD PMID:15337698 RGD:1580149 NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251
JBrowse link
G Npr3 natriuretic peptide receptor 3 IDA RGD PMID:15337698 RGD:1580149 NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955
JBrowse link
G Npy1r neuropeptide Y receptor Y1 IEP mRNA:decreased expression:heart left ventricle RGD PMID:17562528 RGD:1642307 NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 treatment IMP RGD PMID:12384456 RGD:628368 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
JBrowse link
G Oprd1 opioid receptor, delta 1 IDA RGD PMID:12136724 RGD:2316590 NCBI chr 5:144,306,188...144,340,960
Ensembl chr 5:144,306,188...144,340,960
JBrowse link