RGD DISEASE ONTOLOGY - ANNOTATIONS |
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RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
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Term: | Postoperative Complications |
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Accession: | DOID:9000790
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browse the term
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Definition: | Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery. |
Synonyms: | exact_synonym: | Postoperative Complication |
| primary_id: | MESH:D011183 |
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Alb |
albumin |
spontaneous |
ISO |
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RGD |
PMID:23225108 |
RGD:11035295 |
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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Bche |
butyrylcholinesterase |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:6039104 |
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NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
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F7 |
coagulation factor VII |
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ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:12707733 |
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NCBI chr16:76,489,775...76,500,636
Ensembl chr16:76,489,717...76,500,610
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Nppb |
natriuretic peptide B |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23019395 |
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NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
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Pf4 |
platelet factor 4 |
disease_progression |
ISO |
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RGD |
PMID:20691844 |
RGD:329901811 |
NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365
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Pomc |
proopiomelanocortin |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:4371370 |
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NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
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Epo |
erythropoietin |
treatment |
ISO |
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RGD |
PMID:22149012 |
RGD:10400902 |
NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
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F3 |
coagulation factor III, tissue factor |
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IEP |
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RGD |
PMID:9916935 |
RGD:11341701 |
NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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Hnrnpk |
heterogeneous nuclear ribonucleoprotein K |
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ISO |
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RGD |
PMID:21489814 |
RGD:155260371 |
NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997
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Pdgfd |
platelet derived growth factor D |
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ISO |
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RGD |
PMID:19213942 |
RGD:9854642 |
NCBI chr 8:3,488,448...3,722,395
Ensembl chr 8:3,488,423...3,722,395
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Ager |
advanced glycosylation end product-specific receptor |
treatment |
IEP |
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RGD |
PMID:22217518 PMID:23769041 |
RGD:7245568, RGD:8695995 |
NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
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C3 |
complement C3 |
treatment |
IDA |
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RGD |
PMID:25122638 |
RGD:11040803 |
NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
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Cd40 |
CD40 molecule |
treatment |
IDA |
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RGD |
PMID:22826618 |
RGD:11352297 |
NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
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Cd40lg |
CD40 ligand |
treatment |
IDA |
liver |
RGD |
PMID:22826618 |
RGD:11352297 |
NCBI chr X:135,127,052...135,138,768
Ensembl chr X:135,126,969...135,138,306
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F7 |
coagulation factor VII |
treatment |
ISO |
human protein in a rat model |
RGD |
PMID:12095034 |
RGD:11049508 |
NCBI chr16:76,489,775...76,500,636
Ensembl chr16:76,489,717...76,500,610
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Hmgb1 |
high mobility group box 1 |
treatment |
IEP |
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RGD |
PMID:22217518 |
RGD:7245568 |
NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565 Ensembl chr16:5,901,586...5,978,565
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Kcnn4 |
potassium calcium-activated channel subfamily N member 4 |
ameliorates |
IMP |
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RGD |
PMID:24312257 |
RGD:401700379 |
NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340
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Mtor |
mechanistic target of rapamycin kinase |
treatment |
IDA |
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RGD |
PMID:23985719 |
RGD:10041002 |
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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Tnf |
tumor necrosis factor |
treatment |
IMP |
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RGD |
PMID:24598936 |
RGD:10450586 |
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Aco1 |
aconitase 1 |
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IEP |
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RGD |
PMID:20176611 |
RGD:11541086 |
NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
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Alb |
albumin |
disease_progression |
ISO |
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RGD |
PMID:24370342 |
RGD:11035281 |
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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Ccl3 |
C-C motif chemokine ligand 3 |
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ISO |
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RGD |
PMID:17298994 |
RGD:7241819 |
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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Ccn2 |
cellular communication network factor 2 |
disease_progression |
IEP |
mRNA, protein:increased expression:kidney (rat) |
RGD |
PMID:19921985 |
RGD:150517553 |
NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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Clu |
clusterin |
treatment |
IEP |
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RGD |
PMID:22494435 |
RGD:9068431 |
NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
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Cs |
citrate synthase |
treatment |
IDA |
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RGD |
PMID:20005400 |
RGD:243048470 |
NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
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Mmp3 |
matrix metallopeptidase 3 |
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ISO |
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RGD |
PMID:22845765 |
RGD:7241226 |
NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
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Mmp7 |
matrix metallopeptidase 7 |
treatment |
IDA |
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RGD |
PMID:18209025 |
RGD:9685339 |
NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
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Pdgfa |
platelet derived growth factor subunit A |
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IEP |
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RGD |
PMID:11889420 |
RGD:11080974 |
NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
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Pdgfb |
platelet derived growth factor subunit B |
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IEP |
mRNA:increased expression:kidney: |
RGD |
PMID:15785371 PMID:11889420 |
RGD:10449491, RGD:11080974 |
NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
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Pdgfra |
platelet derived growth factor receptor alpha |
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IEP |
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RGD |
PMID:11889420 |
RGD:11080974 |
NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
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Pdgfrb |
platelet derived growth factor receptor beta |
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IEP |
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RGD |
PMID:11889420 |
RGD:11080974 |
NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
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Plau |
plasminogen activator, urokinase |
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ISO |
protein:increased secretion:T lymphocyte (human) |
RGD |
PMID:16387096 |
RGD:7241259 |
NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
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Pparg |
peroxisome proliferator-activated receptor gamma |
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ISO |
protein:increased expression:kidney: |
RGD |
PMID:16221712 |
RGD:13208600 |
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Serpine1 |
serpin family E member 1 |
treatment |
ISO |
protein:increased expression:kidney: |
RGD |
PMID:16221712 PMID:18192922 |
RGD:13208600, RGD:13208601 |
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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Epas1 |
endothelial PAS domain protein 1 |
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IEP |
mRNA:increased expression:lung |
RGD |
PMID:22305384 |
RGD:10395369 |
NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
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Chrng |
cholinergic receptor nicotinic gamma subunit |
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ISO |
ClinVar Annotator: match by term: CHRNG-related disorder CTD Direct Evidence: marker/mechanism |
OMIM ClinVar CTD |
PMID:16826520 PMID:16826531 PMID:22167768 PMID:24038971 PMID:24254455 PMID:25608830 PMID:25741868 PMID:25957469 PMID:26578207 PMID:26752647 PMID:27245440 PMID:28492532 PMID:30868735 PMID:31230720 PMID:33060286 PMID:34440395 More...
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NCBI chr 9:87,878,085...87,884,193
Ensembl chr 9:87,878,085...87,914,482
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Myh3 |
myosin heavy chain 3 |
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ISO |
ClinVar Annotator: match by term: Contractures, pterygia, and spondylocarpotarsal fusion syndrome 1A | ClinVar Annotator: match by term: Contractures, pterygia, and variable skeletal fusions syndrome 1A CTD Direct Evidence: marker/mechanism |
OMIM ClinVar CTD |
PMID:9536098 PMID:17576681 PMID:18414213 PMID:18470895 PMID:25741868 PMID:25957469 PMID:27381093 PMID:28492532 PMID:29314551 PMID:29805041 PMID:30008475 PMID:32902138 PMID:33726816 PMID:34204301 PMID:34440395 PMID:35169139 More...
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NCBI chr10:51,770,177...51,793,994
Ensembl chr10:51,770,177...51,793,992
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Chrna1 |
cholinergic receptor nicotinic alpha 1 subunit |
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ISO |
ClinVar Annotator: match by term: Autosomal recessive multiple pterygium syndrome |
ClinVar |
PMID:25741868 PMID:28492532 |
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NCBI chr 3:58,454,763...58,469,832
Ensembl chr 3:58,454,744...58,469,840
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Chrnd |
cholinergic receptor nicotinic delta subunit |
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ISO |
ClinVar Annotator: match by term: Autosomal recessive multiple pterygium syndrome |
ClinVar |
PMID:25741868 PMID:28492532 |
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NCBI chr 9:87,862,417...87,870,833
Ensembl chr 9:87,862,407...87,870,833
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Chrng |
cholinergic receptor nicotinic gamma subunit |
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ISO |
ClinVar Annotator: match by term: Autosomal recessive multiple pterygium syndrome |
ClinVar |
PMID:15704180 PMID:16199547 PMID:16826520 PMID:16826531 PMID:22167768 PMID:23261301 PMID:24038971 PMID:24254455 PMID:24319099 PMID:25326635 PMID:25411939 PMID:25608830 PMID:25741868 PMID:25957469 PMID:26578207 PMID:26752647 PMID:27245440 PMID:28492532 PMID:29054425 PMID:30868735 PMID:31230720 PMID:31354645 PMID:31680349 PMID:32901917 PMID:33060286 PMID:34008892 PMID:34440395 PMID:35904974 More...
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NCBI chr 9:87,878,085...87,884,193
Ensembl chr 9:87,878,085...87,914,482
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Myh3 |
myosin heavy chain 3 |
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ISO |
ClinVar Annotator: match by term: CONTRACTURES, PTERYGIA, AND SPONDYLOCARPOTARSAL FUSION SYNDROME 1B | ClinVar Annotator: match by term: Contractures, pterygia, and variable skeletal fusions syndrome 1B |
OMIM ClinVar |
PMID:9536098 PMID:17576681 PMID:18414213 PMID:25741868 PMID:25741870 PMID:28492532 PMID:29805041 PMID:32902138 PMID:33726816 PMID:34204301 PMID:34440395 PMID:35169139 More...
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NCBI chr10:51,770,177...51,793,994
Ensembl chr10:51,770,177...51,793,992
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Btbd1 |
BTB domain containing 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16115977 |
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NCBI chr 1:135,734,549...135,773,067
Ensembl chr 1:135,734,589...135,771,981
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Zfand6 |
zinc finger AN1-type containing 6 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16115977 |
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NCBI chr 1:138,581,002...138,652,052
Ensembl chr 1:138,581,002...138,651,939
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Kit |
KIT proto-oncogene receptor tyrosine kinase |
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IEP |
mRNA,protein:decreased expression:stomach: |
RGD |
PMID:20040059 |
RGD:12911222 |
NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
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Kitlg |
KIT ligand |
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IEP |
mRNA:decreased expression:stomach: |
RGD |
PMID:20040059 |
RGD:12911222 |
NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
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Egr1 |
early growth response 1 |
treatment |
IMP |
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RGD |
PMID:23586030 |
RGD:10395312 |
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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Hmox1 |
heme oxygenase 1 |
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ISO |
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RGD |
PMID:12958201 |
RGD:1598395 |
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Mmp2 |
matrix metallopeptidase 2 |
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ISO |
associated with Renal Insufficiency; mRNA:increased expression:arteriovenous fistula (mouse) |
RGD |
PMID:20598569 |
RGD:7207202 |
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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Nos3 |
nitric oxide synthase 3 |
susceptibility |
ISO |
DNA:repeats:intron |
RGD |
PMID:17365407 |
RGD:11533930 |
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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Plau |
plasminogen activator, urokinase |
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ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:8025938 PMID:8416330 PMID:10392865 PMID:11041470 |
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NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
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Ace |
angiotensin I converting enzyme |
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IEP |
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RGD |
PMID:15001561 |
RGD:13515113 |
NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
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Agt |
angiotensinogen |
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IEP |
protein:increased expression:plasma |
RGD |
PMID:15001561 |
RGD:13515113 |
NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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Ahr |
aryl hydrocarbon receptor |
treatment |
IEP |
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RGD |
PMID:22079846 PMID:37387514 |
RGD:401794136, RGD:407419876 |
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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Atp5f1d |
ATP synthase F1 subunit delta |
treatment |
IEP |
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RGD |
PMID:24232000 |
RGD:13792678 |
NCBI chr 7:9,560,604...9,565,919
Ensembl chr 7:9,560,608...9,565,929
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Casp3 |
caspase 3 |
treatment |
IEP |
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RGD |
PMID:23946597 |
RGD:13782356 |
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp9 |
caspase 9 |
treatment |
IEP |
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RGD |
PMID:23946597 |
RGD:13782356 |
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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Ccl2 |
C-C motif chemokine ligand 2 |
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IEP |
mRNA:increased expression:small intestine |
RGD |
PMID:18475188 |
RGD:2307016 |
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Cd14 |
CD14 molecule |
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IEP |
protein:increased expression:heart, kidney, liver, lung |
RGD |
PMID:22493902 |
RGD:9685194 |
NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
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Cldn1 |
claudin 1 |
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IEP |
protein:decreased expression:colon: |
RGD |
PMID:19929946 |
RGD:2325127 |
NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
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Cldn3 |
claudin 3 |
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IEP |
protein:decreased expression:colon: |
RGD |
PMID:19929946 |
RGD:2325127 |
NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001
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Cldn5 |
claudin 5 |
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IEP |
protein:decreased expression:colon: |
RGD |
PMID:19929946 |
RGD:2325127 |
NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992
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Crp |
C-reactive protein |
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IEP |
protein:increased expression:intestine: |
RGD |
PMID:17981193 |
RGD:5129536 |
NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
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Csf3 |
colony stimulating factor 3 |
treatment |
ISO |
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RGD |
PMID:9117128 |
RGD:11039476 |
NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
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Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
treatment |
IEP |
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RGD |
PMID:22079846 |
RGD:401794136 |
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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F7 |
coagulation factor VII |
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ISO |
human protein in a rat model |
RGD |
PMID:22920553 |
RGD:11041662 |
NCBI chr16:76,489,775...76,500,636
Ensembl chr16:76,489,717...76,500,610
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Faslg |
Fas ligand |
treatment |
IEP |
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RGD |
PMID:29170412 |
RGD:13792603 |
NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
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Gpt |
glutamic--pyruvic transaminase |
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IEP |
protein:increased expression:serum |
RGD |
PMID:16557159 |
RGD:401717563 |
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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Hmgb1 |
high mobility group box 1 |
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IEP |
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RGD |
PMID:22093738 |
RGD:10402181 |
NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565 Ensembl chr16:5,901,586...5,978,565
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Hmox1 |
heme oxygenase 1 |
treatment |
IEP |
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RGD |
PMID:19362701 |
RGD:10766423 |
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Hp |
haptoglobin |
treatment |
IEP |
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RGD |
PMID:11922743 |
RGD:11041790 |
NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
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Icam1 |
intercellular adhesion molecule 1 |
treatment |
IEP |
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RGD |
PMID:12095141 PMID:22079846 |
RGD:11522715, RGD:401794136 |
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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Il6 |
interleukin 6 |
treatment |
IDA IEP |
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RGD |
PMID:11959089 PMID:22079846 |
RGD:11062110, RGD:401794136 |
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Jak2 |
Janus kinase 2 |
|
IMP |
|
RGD |
PMID:22777122 |
RGD:10403072 |
NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
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G |
Lbp |
lipopolysaccharide binding protein |
|
IEP |
protein:increased expression:heart, kidney, liver, lung |
RGD |
PMID:22493902 |
RGD:9685194 |
NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586
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G |
Mbl2 |
mannose binding lectin 2 |
severity |
ISO |
DNA:polymorphisms:exon: |
RGD |
PMID:19477015 |
RGD:12910933 |
NCBI chr 1:228,016,439...228,024,736
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G |
Mir155 |
microRNA 155 |
|
ISO |
miRNA:increased expression:Peyer's patch |
RGD |
PMID:30206757 |
RGD:21409753 |
NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
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G |
Mir21 |
microRNA 21 |
|
IEP |
|
RGD |
PMID:30309483 |
RGD:41410822 |
NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
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G |
Nfkbia |
NFKB inhibitor alpha |
treatment |
IEP |
|
RGD |
PMID:22079846 |
RGD:401794136 |
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nos3 |
nitric oxide synthase 3 |
treatment |
IDA |
|
RGD |
PMID:16610051 |
RGD:7777112 |
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
treatment |
IEP |
|
RGD |
PMID:28382390 |
RGD:13440093 |
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
disease_progression |
IEP |
mRNA:decreased expression:liver (rat) |
RGD |
PMID:23331901 |
RGD:15042883 |
NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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|
G |
Parg |
poly (ADP-ribose) glycohydrolase |
treatment |
IMP |
|
RGD |
PMID:15791006 |
RGD:13514040 |
NCBI chr16:7,436,429...7,544,276
Ensembl chr16:7,436,476...7,544,273
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|
G |
Ppp1r15a |
protein phosphatase 1, regulatory subunit 15A |
|
ISO |
mRNA:increased expression:jejunum (human) |
RGD |
PMID:20965186 |
RGD:9999150 |
NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
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|
G |
Proc |
protein C, inactivator of coagulation factors Va and VIIIa |
treatment |
ISO |
|
RGD |
PMID:15187522 |
RGD:11250409 |
NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
treatment |
IEP |
|
RGD |
PMID:22079846 |
RGD:401794136 |
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Serpinc1 |
serpin family C member 1 |
treatment |
IEP |
|
RGD |
PMID:21046505 |
RGD:11035258 |
NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293
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G |
Serpine1 |
serpin family E member 1 |
|
IDA |
protein:increased activity:plasma (rat) |
RGD |
PMID:12717359 |
RGD:11081012 |
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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G |
Socs1 |
suppressor of cytokine signaling 1 |
treatment |
IEP |
|
RGD |
PMID:27538408 |
RGD:151347179 |
NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
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G |
Tnf |
tumor necrosis factor |
treatment |
IEP |
|
RGD |
PMID:22079846 |
RGD:401794136 |
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Traf6 |
TNF receptor associated factor 6 |
|
IEP |
|
RGD |
PMID:27538408 |
RGD:151347179 |
NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
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G |
Trem1 |
triggering receptor expressed on myeloid cells 1 |
ameliorates |
IDA |
associated with mesenteric vascular occlusion; |
RGD |
PMID:18091551 |
RGD:127284848 |
NCBI chr 9:12,763,819...12,779,285
Ensembl chr 9:12,763,819...12,779,203
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G |
Vwf |
von Willebrand factor |
|
IEP |
protein:increased expression:plasma: |
RGD |
PMID:10365842 |
RGD:11080742 |
NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539
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G |
Xdh |
xanthine dehydrogenase |
treatment |
IEP |
|
RGD |
PMID:23010742 |
RGD:13209016 |
NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
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G |
Ace |
angiotensin I converting enzyme |
|
IMP |
|
RGD |
PMID:21680852 |
RGD:6893484 |
NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
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G |
Ace2 |
angiotensin converting enzyme 2 |
|
IEP |
mRNA:decreased expression:kidney |
RGD |
PMID:20528771 |
RGD:9685432 |
NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977
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G |
Acta1 |
actin, alpha 1, skeletal muscle |
ameliorates |
ISO |
|
RGD |
PMID:24920753 |
RGD:329845564 |
NCBI chr19:51,883,709...51,886,735
Ensembl chr19:51,883,715...51,886,742
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G |
Acvr2b |
activin A receptor type 2B |
treatment |
ISO |
human construct in rat model |
RGD |
PMID:27732750 |
RGD:329322881 |
NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:119,138,812...119,170,458
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G |
Adam17 |
ADAM metallopeptidase domain 17 |
treatment |
IEP |
|
RGD |
PMID:22015440 |
RGD:13703100 |
NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
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G |
Adam2 |
ADAM metallopeptidase domain 2 |
|
IEP |
|
RGD |
PMID:11967014 |
RGD:10047130 |
NCBI chr15:40,242,651...40,284,025
Ensembl chr15:40,242,783...40,283,952
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G |
Adamts1 |
ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
|
IEP |
|
RGD |
PMID:18272597 |
RGD:9684850 |
NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
treatment |
ISO |
|
RGD |
PMID:21412771 |
RGD:8695946 |
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Adm |
adrenomedullin |
treatment |
IEP ISO |
protein:increased expression:serum: |
RGD |
PMID:20538296 PMID:20538296 |
RGD:7364948, RGD:7364948 |
NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
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G |
Akr1a1 |
aldo-keto reductase family 1 member A1 |
|
ISO |
|
RGD |
PMID:31089212 |
RGD:27226686 |
NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
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G |
Aldh2 |
aldehyde dehydrogenase 2 family member |
|
ISO |
|
RGD |
PMID:22022451 |
RGD:7241603 |
NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
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G |
Anxa1 |
annexin A1 |
treatment |
IDA |
|
RGD |
PMID:20953576 |
RGD:7421585 |
NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
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G |
Anxa5 |
annexin A5 |
|
ISO |
|
RGD |
PMID:21918686 |
RGD:7242028 |
NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
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G |
Apaf1 |
apoptotic peptidase activating factor 1 |
treatment |
IEP |
|
RGD |
PMID:26362957 |
RGD:13703110 |
NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
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G |
Apoa1 |
apolipoprotein A1 |
treatment |
ISO |
|
RGD |
PMID:18535924 |
RGD:7241574 |
NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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G |
Atm |
ATM serine/threonine kinase |
|
IEP |
protein:increased expression:kidney |
RGD |
PMID:22768306 |
RGD:10053607 |
NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
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G |
Bax |
BCL2 associated X, apoptosis regulator |
treatment |
IEP |
|
RGD |
PMID:23151253 |
RGD:10054101 |
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
treatment |
IEP |
|
RGD |
PMID:18221257 PMID:29285062 |
RGD:2293026, RGD:13792599 |
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bdkrb1 |
bradykinin receptor B1 |
|
ISO |
|
RGD |
PMID:18725957 |
RGD:7241559 |
NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
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G |
Becn1 |
beclin 1 |
treatment |
IEP |
|
RGD |
PMID:26412257 |
RGD:11561958 |
NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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G |
Bmi1 |
BMI1 proto-oncogene, polycomb ring finger |
|
ISO |
mRNA:altered expression:kidney (mouse) |
RGD |
PMID:18467665 |
RGD:155631277 |
NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690
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|
G |
Bnip3 |
BCL2 interacting protein 3 |
|
IEP |
mRNA, protein:increased expression:kidney |
RGD |
PMID:23698117 |
RGD:11561968 |
NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
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G |
C3 |
complement C3 |
treatment |
IEP |
|
RGD |
PMID:19691975 |
RGD:7411689 |
NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
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G |
Calca |
calcitonin-related polypeptide alpha |
|
IMP |
|
RGD |
PMID:19194162 |
RGD:7204479 |
NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
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G |
Casp3 |
caspase 3 |
treatment |
IEP |
|
RGD |
PMID:23151253 |
RGD:10054101 |
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp7 |
caspase 7 |
|
IEP |
|
RGD |
PMID:17596683 |
RGD:5684536 |
NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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G |
Ccl11 |
C-C motif chemokine ligand 11 |
treatment |
ISO |
|
RGD |
PMID:22160777 |
RGD:7247742 |
NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
ameliorates treatment |
ISO IDA |
mRNA, protein:increased expression:kidney, lung, serum |
RGD |
PMID:24920753 PMID:20396927 PMID:18650485 |
RGD:329845564, RGD:4891433, RGD:11526113 |
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccn1 |
cellular communication network factor 1 |
ameliorates |
ISO |
|
RGD |
PMID:24920753 |
RGD:329845564 |
NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
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G |
Cd14 |
CD14 molecule |
|
ISO |
mRNA,protein:increased expression:kidney |
RGD |
PMID:10966493 |
RGD:7204444 |
NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
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G |
Cd40 |
CD40 molecule |
treatment |
IMP |
|
RGD |
PMID:25993320 |
RGD:11251055 |
NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
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G |
Cfb |
complement factor B |
|
ISO |
|
RGD |
PMID:16467447 PMID:12538716 |
RGD:7242709, RGD:7242734 |
NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
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G |
Cfh |
complement factor H |
treatment |
IEP ISO |
protein:decreased expression:serum: |
RGD |
PMID:20538296 PMID:20538296 |
RGD:7364948, RGD:7364948 |
NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838
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G |
Ciita |
class II, major histocompatibility complex, transactivator |
|
ISO |
|
RGD |
PMID:14569092 |
RGD:7242896 |
NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440
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G |
Cited1 |
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 |
|
ISO |
mRNA:altered expression:kidney (mouse) |
RGD |
PMID:18467665 |
RGD:155631277 |
NCBI chr X:67,350,376...67,355,072
Ensembl chr X:67,350,373...67,355,162
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G |
Col1a1 |
collagen type I alpha 1 chain |
ameliorates |
ISO |
|
RGD |
PMID:24920753 |
RGD:329845564 |
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Col3a1 |
collagen type III alpha 1 chain |
ameliorates |
ISO |
|
RGD |
PMID:24920753 |
RGD:329845564 |
NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
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G |
Csf1 |
colony stimulating factor 1 |
|
ISO |
mRNA:increased expression:kidney |
RGD |
PMID:23143303 PMID:19196448 |
RGD:7257565, RGD:7257570 |
NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
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G |
Csf1r |
colony stimulating factor 1 receptor |
|
ISO |
|
RGD |
PMID:23143303 |
RGD:7257565 |
NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
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G |
Ctla4 |
cytotoxic T-lymphocyte-associated protein 4 |
|
ISO |
|
RGD |
PMID:22189844 PMID:9407517 |
RGD:7204675, RGD:7204727 |
NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
ameliorates |
ISO |
|
RGD |
PMID:24920753 |
RGD:329845564 |
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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G |
Cxcr2 |
C-X-C motif chemokine receptor 2 |
|
ISO |
|
RGD |
PMID:20038794 |
RGD:7257679 |
NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425
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G |
Cxcr4 |
C-X-C motif chemokine receptor 4 |
|
IEP |
protein:increased expression:kidney |
RGD |
PMID:29073721 |
RGD:13825150 |
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
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G |
Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
treatment |
IMP |
|
RGD |
PMID:23552495 |
RGD:7244372 |
NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
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G |
Daxx |
death-domain associated protein |
|
ISO |
protein:increased expression:kidney: |
RGD |
PMID:18480747 PMID:18480747 |
RGD:9587836, RGD:9587836 |
NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
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G |
Ddr1 |
discoidin domain receptor tyrosine kinase 1 |
|
ISO |
protein:increased expression:kidney (mouse) |
RGD |
PMID:31383731 |
RGD:151347540 |
NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468
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|
G |
Dhfr |
dihydrofolate reductase |
treatment |
IEP |
mRNA,protein:decreased expression:kidney: |
RGD |
PMID:18408363 |
RGD:11040540 |
NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
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G |
Drd3 |
dopamine receptor D3 |
treatment |
IDA |
|
RGD |
PMID:25989500 |
RGD:13506961 |
NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
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G |
Eed |
embryonic ectoderm development |
|
ISO |
mRNA:altered expression:kidney (mouse) |
RGD |
PMID:18467665 |
RGD:155631277 |
NCBI chr 1:143,867,875...143,895,008
Ensembl chr 1:143,867,875...143,894,974
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G |
Egln1 |
egl-9 family hypoxia-inducible factor 1 |
|
IEP |
mRNA, protein:decreased expression:kidney |
RGD |
PMID:19349364 |
RGD:11252083 |
NCBI chr19:52,867,900...52,907,308
Ensembl chr19:52,869,486...52,907,777
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G |
Egln3 |
egl-9 family hypoxia-inducible factor 3 |
|
IEP |
mRNA, protein:decreased expression:kidney |
RGD |
PMID:19349364 |
RGD:11252083 |
NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
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G |
Elane |
elastase, neutrophil expressed |
treatment |
IMP |
|
RGD |
PMID:16980042 |
RGD:10450580 |
NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100
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G |
Eng |
endoglin |
|
IEP ISO |
mRNA, protein:increased expression:kidney (rat) |
RGD |
PMID:16751653 PMID:16751653 |
RGD:7248779, RGD:7248779 |
NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
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G |
Ep300 |
E1A binding protein p300 |
|
IEP |
protein:altered localization:kidney (rat) |
RGD |
PMID:23936185 |
RGD:7257563 |
NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088 Ensembl chr 7:113,106,247...113,136,088
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G |
Epo |
erythropoietin |
treatment |
ISO |
|
RGD |
PMID:19961832 PMID:25581532 |
RGD:10401077, RGD:11041698 |
NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
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G |
Ezh2 |
enhancer of zeste 2 polycomb repressive complex 2 subunit |
|
ISO |
mRNA:altered expression:kidney (mouse) |
RGD |
PMID:18467665 |
RGD:155631277 |
NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
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G |
F3 |
coagulation factor III, tissue factor |
|
IEP |
protein:decreased expression:lung |
RGD |
PMID:25883098 |
RGD:11341735 |
NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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|
G |
Fas |
Fas cell surface death receptor |
treatment |
IEP |
|
RGD |
PMID:29285062 |
RGD:13792599 |
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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|
G |
Faslg |
Fas ligand |
treatment |
IEP |
|
RGD |
PMID:29285062 |
RGD:13792599 |
NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
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|
G |
Fcgr1a |
Fc gamma receptor 1A |
treatment |
ISO |
|
RGD |
PMID:22402584 |
RGD:9685699 |
NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994
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|
G |
Fga |
fibrinogen alpha chain |
|
IEP |
mRNA,protein:increased expression:kidney |
RGD |
PMID:21685370 |
RGD:7175292 |
NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528
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|
G |
Fgb |
fibrinogen beta chain |
treatment |
IEP ISO |
mRNA, protein:increased expression:kidney |
RGD |
PMID:21685370 PMID:21685370 |
RGD:7175292, RGD:7175292 |
NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
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|
G |
Fgfr2 |
fibroblast growth factor receptor 2 |
exacerbates ameliorates |
ISO IMP |
protein:increased phosphorylation:kidney (mouse) |
RGD |
PMID:20591940 PMID:22688984 PMID:29344510 PMID:32523960 |
RGD:155663667, RGD:155882537, RGD:155782904, RGD:155782882 |
NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
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G |
Fgg |
fibrinogen gamma chain |
|
IEP |
mRNA,protein:increased expression:kidney |
RGD |
PMID:21685370 |
RGD:7175292 |
NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
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|
G |
Fn1 |
fibronectin 1 |
|
IEP |
|
RGD |
PMID:11352844 |
RGD:7205629 |
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
|
ISO |
|
RGD |
PMID:19095962 |
RGD:7242184 |
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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|
G |
G6pd |
glucose-6-phosphate dehydrogenase |
|
IEP |
|
RGD |
PMID:17250641 |
RGD:2307361 |
NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
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|
G |
Gfer |
growth factor, augmenter of liver regeneration |
treatment |
IEP ISO |
protein:increased expression:kidney: |
RGD |
PMID:20332418 PMID:20332418 |
RGD:9685723, RGD:9685723 |
NCBI chr10:13,718,489...13,721,782
Ensembl chr10:13,718,489...13,720,869
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G |
Glo1 |
glyoxalase 1 |
|
IMP |
|
RGD |
PMID:19211689 |
RGD:7242566 |
NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
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|
G |
Gpx3 |
glutathione peroxidase 3 |
|
IEP |
protein:decreased expression:kidney mRNA:decreased expression:kidney |
RGD |
PMID:37033969 PMID:22442209 |
RGD:401827821, RGD:401827906 |
NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
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|
G |
Gsr |
glutathione-disulfide reductase |
treatment |
IEP |
|
RGD |
PMID:24630969 |
RGD:10401866 |
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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|
G |
Gstm1 |
glutathione S-transferase mu 1 |
|
IEP |
mRNA, protein:decreased expression:kidney |
RGD |
PMID:29137244 |
RGD:158014894 |
NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
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|
G |
Gstt1 |
glutathione S-transferase theta 1 |
|
IEP |
protein:decreased expression:kidney |
RGD |
PMID:37033969 |
RGD:401827821 |
NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
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|
G |
H2ax |
H2A.X variant histone |
treatment |
IEP |
|
RGD |
PMID:23726287 |
RGD:8693706 |
NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 Ensembl chr 4:44,671,786...44,673,239
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G |
Has1 |
hyaluronan synthase 1 |
|
IEP |
|
RGD |
PMID:22529164 |
RGD:9588636 |
NCBI chr 1:58,693,411...58,705,653
Ensembl chr 1:58,693,411...58,705,397
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G |
Has2 |
hyaluronan synthase 2 |
|
IEP |
|
RGD |
PMID:22529164 |
RGD:9588636 |
NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933
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|
G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
|
IEP ISO |
protein:increased expression:urine: |
RGD |
PMID:23552495 PMID:23019274 PMID:23085062 |
RGD:7244372, RGD:7245495, RGD:7245489 |
NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
treatment severity |
IDA IMP |
|
RGD |
PMID:17519789 PMID:22432008 |
RGD:1626334, RGD:9068883 |
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hmox1 |
heme oxygenase 1 |
treatment |
IMP |
|
RGD |
PMID:21291499 |
RGD:10755580 |
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hsf1 |
heat shock transcription factor 1 |
|
IEP |
protein:increased expression:kidney (rat) |
RGD |
PMID:23102208 |
RGD:10402775 |
NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
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G |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
|
IEP |
|
RGD |
PMID:7569112 |
RGD:7242788 |
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
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G |
Hyal1 |
hyaluronidase 1 |
|
IEP |
|
RGD |
PMID:22529164 |
RGD:9588636 |
NCBI chr 8:108,250,668...108,254,519
Ensembl chr 8:108,250,667...108,260,210
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|
G |
Hyal2 |
hyaluronidase 2 |
|
IEP |
|
RGD |
PMID:22529164 |
RGD:9588636 |
NCBI chr 8:108,241,895...108,246,853
Ensembl chr 8:108,243,133...108,246,850
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|
G |
Ifng |
interferon gamma |
treatment |
ISO |
|
RGD |
PMID:28355607 |
RGD:14975115 |
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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|
G |
Igf1r |
insulin-like growth factor 1 receptor |
|
IEP |
mRNA: increased expression: kidney: 3 and 5 days post ischemia |
RGD |
PMID:10990448 |
RGD:7242905 |
NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
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|
G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
treatment |
IMP |
|
RGD |
PMID:19546526 |
RGD:7495779 |
NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
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G |
Il10 |
interleukin 10 |
treatment |
IDA ISO |
|
RGD |
PMID:24079335 PMID:28664613 |
RGD:7364864, RGD:14975137 |
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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|
G |
Il12b |
interleukin 12B |
ameliorates |
ISO |
|
RGD |
PMID:24920753 |
RGD:329845564 |
NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
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|
G |
Il18 |
interleukin 18 |
treatment |
IMP |
|
RGD |
PMID:22089199 |
RGD:8655971 |
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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|
G |
Il1b |
interleukin 1 beta |
ameliorates |
IDA ISO |
|
RGD |
PMID:20030532 PMID:24920753 |
RGD:7175501, RGD:329845564 |
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il1rn |
interleukin 1 receptor antagonist |
|
ISO |
rat model treated with human protein mouse model treated with human protein |
RGD |
PMID:18363573 PMID:9555664 PMID:16849996 |
RGD:6907101, RGD:6909149, RGD:6907359 |
NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
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G |
Il6 |
interleukin 6 |
ameliorates |
ISO |
|
RGD |
PMID:24920753 |
RGD:329845564 |
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Inhbb |
inhibin subunit beta B |
|
IEP |
protein:increased expression:serum (rat) |
RGD |
PMID:27732750 |
RGD:329322881 |
NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832
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G |
Itgb2 |
integrin subunit beta 2 |
|
ISO IMP |
Associated with renal transplant patients |
RGD |
PMID:20504838 PMID:11007822 |
RGD:6907049, RGD:6907073 |
NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
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|
G |
Kcnj11 |
potassium inwardly-rectifying channel, subfamily J, member 11 |
|
IEP |
protein:decreased expression:kidney |
RGD |
PMID:21250976 |
RGD:7297045 |
NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
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G |
Kl |
Klotho |
treatment |
IEP ISO |
mRNA,protein:decreased expression:renal tubule: |
RGD |
PMID:16204278 PMID:16204278 |
RGD:10403064, RGD:10403064 |
NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080
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|
G |
Kmt2a |
lysine methyltransferase 2A |
|
ISO |
protein:increased expression:kidney (mouse) |
RGD |
PMID:31570196 |
RGD:155888490 |
NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181
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|
G |
Lcn2 |
lipocalin 2 |
|
IEP ISO |
protein:increased expression:urine: mRNA,protein:increased expression:kidney,urine mRNA,protein:increased expression:kidney: |
RGD |
PMID:23364806 PMID:27800610 PMID:20181666 PMID:23085062 |
RGD:7245469, RGD:126790572, RGD:126779563, RGD:7245489 |
NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
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G |
Lep |
leptin |
resistance |
IDA |
|
RGD |
PMID:22969992 |
RGD:6909133 |
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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|
G |
Lgals3 |
galectin 3 |
|
IEP |
mRNA:increased expression:kidney |
RGD |
PMID:10980121 |
RGD:9685228 |
NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
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|
G |
Map1lc3a |
microtubule-associated protein 1 light chain 3 alpha |
treatment |
ISO IEP |
|
RGD |
PMID:20075199 PMID:26412257 |
RGD:11561916, RGD:11561958 |
NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670
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|
G |
Map3k5 |
mitogen-activated protein kinase kinase kinase 5 |
treatment |
IMP |
|
RGD |
PMID:23952292 |
RGD:10412647 |
NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
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G |
Mc1r |
melanocortin 1 receptor |
|
IEP |
protein:decreased expression:kidney outer medulla |
RGD |
PMID:18790174 |
RGD:5687322 |
NCBI chr19:51,452,448...51,455,375
Ensembl chr19:51,453,239...51,454,192
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G |
Mir146a |
microRNA 146a |
treatment |
IEP |
|
RGD |
PMID:27760486 |
RGD:155882556 |
NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
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|
G |
Mir320a |
microRNA 320a |
treatment |
IEP |
|
RGD |
PMID:31089916 PMID:27760486 |
RGD:155882543, RGD:155882556 |
NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473
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G |
Mir381 |
microRNA 381 |
|
IEP |
RNA:decreased expression:kidney |
RGD |
PMID:29073721 |
RGD:13825150 |
NCBI chr 6:128,740,976...128,741,036
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G |
Mir423 |
microRNA 423 |
treatment |
IMP |
|
RGD |
PMID:29137244 |
RGD:158014894 |
NCBI chr10:61,914,142...61,914,220
Ensembl chr10:61,914,133...61,914,226
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G |
Mir494 |
microRNA 494 |
ameliorates |
ISO |
|
RGD |
PMID:23160513 |
RGD:155883172 |
NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793
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G |
Mpo |
myeloperoxidase |
|
IEP ISO |
protein:increased activity:kidney |
RGD |
PMID:22950848 PMID:18055546 |
RGD:6909167, RGD:7174699 |
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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G |
Muc1 |
mucin 1, cell surface associated |
treatment |
IDA |
|
RGD |
PMID:22019164 |
RGD:7245959 |
NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
|
IEP |
mRNA:increased expression:kidney (rat) |
RGD |
PMID:17220792 |
RGD:7207777 |
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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G |
Ndufb8 |
NADH:ubiquinone oxidoreductase subunit B8 |
|
IEP ISO |
|
RGD |
PMID:24096033 PMID:22160772 |
RGD:13801197, RGD:13801199 |
NCBI chr 1:243,408,656...243,413,715
Ensembl chr 1:243,408,619...243,413,817
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G |
Nes |
nestin |
|
IEP |
|
RGD |
PMID:24503548 |
RGD:11570523 |
NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777
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|
G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
treatment |
IEP |
|
RGD |
PMID:31089916 |
RGD:155882543 |
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Nos2 |
nitric oxide synthase 2 |
treatment |
IEP |
|
RGD |
PMID:18408363 |
RGD:11040540 |
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nos3 |
nitric oxide synthase 3 |
treatment |
IEP |
|
RGD |
PMID:29291552 PMID:18408363 |
RGD:13504682, RGD:11040540 |
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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G |
Nox1 |
NADPH oxidase 1 |
treatment |
IEP |
|
RGD |
PMID:34244746 |
RGD:329955363 |
NCBI chr X:97,279,058...97,332,291
Ensembl chr X:97,279,056...97,302,236
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G |
Nppa |
natriuretic peptide A |
|
ISO |
|
RGD |
PMID:20471588 |
RGD:7247717 |
NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
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|
G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
treatment |
IEP |
|
RGD |
PMID:21545725 |
RGD:11035217 |
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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|
G |
Nr4a1 |
nuclear receptor subfamily 4, group A, member 1 |
severity |
ISO |
mRNA:increased expression:kidney |
RGD |
PMID:22343121 PMID:22343121 |
RGD:14700869, RGD:14700869 |
NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
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|
G |
Ogg1 |
8-oxoguanine DNA glycosylase |
|
IEP |
|
RGD |
PMID:12531391 |
RGD:2317150 |
NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
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|
G |
Pax2 |
paired box 2 |
|
IEP |
mRNA, protein:increased expression:kidney |
RGD |
PMID:12444203 |
RGD:727468 |
NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321
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|
G |
Pdgfb |
platelet derived growth factor subunit B |
|
IEP |
mRNA,protein:increased expression:tubule, S3 segment: |
RGD |
PMID:10550325 |
RGD:8554477 |
NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
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|
G |
Pdgfra |
platelet derived growth factor receptor alpha |
|
IEP |
mRNA:increased expression:kidney |
RGD |
PMID:10550325 |
RGD:8554477 |
NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
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|
G |
Pdgfrb |
platelet derived growth factor receptor beta |
|
IMP IEP |
mRNA:increased expression:kidney |
RGD |
PMID:12819032 PMID:10550325 |
RGD:1580850, RGD:8554477 |
NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
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|
G |
Peg10 |
paternally expressed 10 |
|
ISO |
mRNA:increased expression:kidney (mouse) |
RGD |
PMID:16778176 |
RGD:401851077 |
NCBI chr 4:32,842,441...32,855,639
Ensembl chr 4:32,848,493...32,852,621
|
|
G |
Pkd2 |
polycystin 2, transient receptor potential cation channel |
|
IEP |
protein:increased expression:kidney (rat) |
RGD |
PMID:12454224 |
RGD:1580868 |
NCBI chr14:5,237,135...5,280,455
Ensembl chr14:5,237,135...5,280,825
|
|
G |
Ppargc1a |
PPARG coactivator 1 alpha |
treatment |
IDA |
|
RGD |
PMID:24918615 |
RGD:10059636 |
NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
|
|
G |
Ptgis |
prostaglandin I2 synthase |
|
ISO |
mRNA:increased expression:kidney (mouse) |
RGD |
PMID:30413885 |
RGD:401959745 |
NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451
|
|
G |
Rnls |
renalase, FAD-dependent amine oxidase |
|
ISO |
mRNA,protein:decreased expression:kidney,plasma: |
RGD |
PMID:23393318 PMID:23393318 |
RGD:7327166, RGD:7327166 |
NCBI chr 1:231,037,481...231,309,855
Ensembl chr 1:231,037,486...231,309,823
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|
G |
Serpina1 |
serpin family A member 1 |
treatment |
ISO |
|
RGD |
PMID:28235038 |
RGD:14695051 |
NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339
|
|
G |
Serpinc1 |
serpin family C member 1 |
severity |
IMP |
|
RGD |
PMID:26108065 PMID:26108065 |
RGD:11354006, RGD:11354006 |
NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293
|
|
G |
Serpinc1em2Mcwi |
serpin family C member 1; ZFN induced mutant 2, Medical College of Wisconsin |
|
IMP |
|
RGD |
PMID:26108065 |
RGD:11354006 |
|
|
G |
Serpine1 |
serpin family E member 1 |
ameliorates |
ISO |
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RGD |
PMID:24920753 |
RGD:329845564 |
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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G |
Shh |
sonic hedgehog signaling molecule |
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ISO |
mRNA, protein:increased expression:kidney |
RGD |
PMID:24744439 |
RGD:12859042 |
NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
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G |
Sirt1 |
sirtuin 1 |
treatment |
IEP |
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RGD |
PMID:22324445 |
RGD:9495930 |
NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
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G |
Six2 |
SIX homeobox 2 |
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ISO |
mRNA:altered expression:kidney (mouse) |
RGD |
PMID:18467665 |
RGD:155631277 |
NCBI chr 6:8,974,859...8,981,345
Ensembl chr 6:8,967,157...8,981,193
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G |
Slc22a1 |
solute carrier family 22 member 1 |
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IEP |
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RGD |
PMID:21835768 |
RGD:7243877 |
NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
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G |
Slc22a2 |
solute carrier family 22 member 2 |
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IEP |
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RGD |
PMID:21835768 |
RGD:7243877 |
NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
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G |
Slc34a1 |
solute carrier family 34 member 1 |
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IEP |
protein:decreased expression:renal proximal tubule, brush border membrane (rat) |
RGD |
PMID:15775707 |
RGD:2311304 |
NCBI chr17:9,218,876...9,233,852
Ensembl chr17:9,218,876...9,233,852
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G |
Src |
SRC proto-oncogene, non-receptor tyrosine kinase |
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IEP |
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RGD |
PMID:12819032 |
RGD:1580850 |
NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
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G |
Stat6 |
signal transducer and activator of transcription 6 |
severity |
ISO |
|
RGD |
PMID:12709397 |
RGD:7244143 |
NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
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G |
Suz12 |
SUZ12 polycomb repressive complex 2 subunit |
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ISO |
mRNA:altered expression:kidney (mouse) |
RGD |
PMID:18467665 |
RGD:155631277 |
NCBI chr10:64,967,035...65,012,916
Ensembl chr10:64,966,967...65,012,738
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G |
Tfpi |
tissue factor pathway inhibitor |
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ISO |
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RGD |
PMID:11796005 |
RGD:11062062 |
NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880
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G |
Tgfb1 |
transforming growth factor, beta 1 |
ameliorates |
ISO |
|
RGD |
PMID:24920753 |
RGD:329845564 |
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Tlr2 |
toll-like receptor 2 |
treatment severity |
IDA ISO |
|
RGD |
PMID:23239000 PMID:11801667 PMID:20130923 PMID:22750071 PMID:23023072 |
RGD:7207892, RGD:7241087, RGD:7240552, RGD:7207896, RGD:7207894 |
NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
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G |
Tlr4 |
toll-like receptor 4 |
treatment |
IDA ISO |
|
RGD |
PMID:23239000 PMID:11801667 PMID:20130923 |
RGD:7207892, RGD:7241087, RGD:7240552 |
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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G |
Tnf |
tumor necrosis factor |
ameliorates |
IEP ISO |
protein:increased expression:serum |
RGD |
PMID:19925291 PMID:24920753 |
RGD:2315112, RGD:329845564 |
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tnfrsf1a |
TNF receptor superfamily member 1A |
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ISO |
mRNA:increased expression:lung |
RGD |
PMID:22728466 |
RGD:7245543 |
NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
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G |
Vcam1 |
vascular cell adhesion molecule 1 |
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IEP |
protein:increased expression:kidney |
RGD |
PMID:20164827 |
RGD:7240507 |
NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
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G |
Vwf |
von Willebrand factor |
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IEP |
protein:increased expression:serum: |
RGD |
PMID:12684225 |
RGD:11080744 |
NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539
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G |
Wt1 |
WT1 transcription factor |
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ISO |
mRNA:altered expression:kidney (mouse) |
RGD |
PMID:18467665 |
RGD:155631277 |
NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643
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G |
Xdh |
xanthine dehydrogenase |
treatment |
IMP |
associated with Diabetes Mellitus, Type 2 |
RGD |
PMID:22995295 PMID:20616412 |
RGD:7247637, RGD:7247695 |
NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
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G |
Zfp667 |
zinc finger protein 667 |
ameliorates |
ISO |
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RGD |
PMID:24920753 |
RGD:329845564 |
NCBI chr 1:67,601,803...67,622,041
Ensembl chr 1:67,601,807...67,622,041
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G |
Ryr1 |
ryanodine receptor 1 |
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ISO |
ClinVar Annotator: match by term: King Denborough syndrome | ClinVar Annotator: match by term: King syndrome |
ClinVar OMIM |
PMID:16940 PMID:18253 PMID:18564 PMID:1510267 PMID:1639409 PMID:1743490 PMID:1774073 PMID:1774074 PMID:1810122 PMID:3356401 PMID:4149045 PMID:7299413 PMID:7511586 PMID:7547049 PMID:7586638 PMID:7633940 PMID:7751854 PMID:7762556 PMID:7889656 PMID:8401544 PMID:8602662 PMID:8661021 PMID:8828983 PMID:9199552 PMID:9334205 PMID:9389851 PMID:9450902 PMID:9497245 PMID:9520251 PMID:9536098 PMID:9873004 PMID:10051009 PMID:10352931 PMID:10484775 PMID:10756965 PMID:10823104 PMID:11448278 PMID:11493496 PMID:11553045 PMID:11575529 PMID:11668625 PMID:11709545 PMID:11741831 PMID:12059893 PMID:12124989 PMID:12151923 PMID:12208234 PMID:12220451 PMID:12237752 PMID:12411788 PMID:12434264 PMID:12642598 PMID:12700608 PMID:12732639 PMID:12937085 PMID:14500992 PMID:14670767 PMID:14732627 PMID:14985404 PMID:15175001 PMID:15210166 PMID:15299003 PMID:15448513 PMID:15731587 PMID:16084090 PMID:16163667 PMID:16199547 PMID:16244001 PMID:16272262 PMID:16372898 PMID:16380615 PMID:16621918 PMID:16732084 PMID:16732090 PMID:16835904 PMID:16917943 PMID:16940308 PMID:16958617 PMID:17033962 PMID:17081152 PMID:17204937 PMID:17365175 PMID:17483490 PMID:17576681 PMID:17667581 PMID:17710899 PMID:17968765 PMID:18063506 PMID:18171678 PMID:18193641 PMID:18253926 PMID:18414213 PMID:18502356 PMID:18505122 PMID:18564801 PMID:18765655 PMID:18813041 PMID:19191329 PMID:19191333 PMID:19346234 PMID:19513315 PMID:19648156 PMID:19685112 PMID:19807743 PMID:19825159 PMID:19919814 PMID:20080402 PMID:20142353 PMID:20301325 PMID:20566647 PMID:20583297 PMID:20681998 PMID:20839240 PMID:20981092 PMID:21062345 PMID:21118704 PMID:21157159 PMID:21455645 PMID:21514828 PMID:21674524 PMID:21795085 PMID:21878807 PMID:21911697 PMID:21918424 PMID:22030266 PMID:22415532 PMID:22418739 PMID:22473935 PMID:22696611 PMID:22851008 PMID:22913516 PMID:22992668 PMID:22995991 PMID:23035052 PMID:23204524 PMID:23308296 PMID:23329375 PMID:23394784 PMID:23459219 PMID:23460944 PMID:23476141 PMID:23478172 PMID:23553484 PMID:23553787 PMID:23558838 PMID:23628358 PMID:23826317 PMID:23842196 PMID:23919265 PMID:24033266 PMID:24055113 PMID:24088041 PMID:24195946 PMID:24215330 PMID:24361844 PMID:24433488 PMID:24627108 PMID:24950660 PMID:24951453 PMID:24961629 PMID:25086907 PMID:25214167 PMID:25268394 PMID:25326635 PMID:25428687 PMID:25476234 PMID:25517095 PMID:25525159 PMID:25558065 PMID:25635128 PMID:25637381 PMID:25658027 PMID:25683120 PMID:25735680 PMID:25741868 PMID:25747005 PMID:25957634 PMID:25958340 PMID:25960145 PMID:25989378 PMID:26019235 PMID:26068069 PMID:26115329 PMID:26332594 PMID:26381711 PMID:26467025 PMID:26578207 PMID:26633545 PMID:26951757 PMID:27058611 PMID:27147545 PMID:27153395 PMID:27159402 PMID:27363342 PMID:27382027 PMID:27431030 PMID:27452334 PMID:27545679 PMID:27558158 PMID:27586648 PMID:27616680 PMID:27646467 PMID:27854218 PMID:27857962 PMID:27918309 PMID:28007021 PMID:28259615 PMID:28269792 PMID:28357410 PMID:28492532 PMID:28687594 PMID:28818389 PMID:29169929 PMID:29172004 PMID:29298851 PMID:29344738 PMID:29382405 PMID:29417091 PMID:29629541 PMID:29635721 PMID:29792937 PMID:30122538 PMID:30155738 PMID:30236257 PMID:30291343 PMID:30325262 PMID:30406384 PMID:30499100 PMID:30609409 PMID:30611313 PMID:30652412 PMID:30788618 PMID:30827497 PMID:30842289 PMID:30864471 PMID:30872186 PMID:31016048 PMID:31055738 PMID:31107960 PMID:31127727 PMID:31165076 PMID:31206373 PMID:31304636 PMID:31407473 PMID:31447099 PMID:31517061 PMID:31559918 PMID:31589614 PMID:31680123 PMID:31680349 PMID:31851124 PMID:31994743 PMID:32054689 PMID:32236737 PMID:32304219 PMID:32403337 PMID:32528171 PMID:32665702 PMID:32978841 PMID:33037202 PMID:33146414 PMID:33333461 PMID:33458582 PMID:33490280 PMID:33564012 PMID:33625594 PMID:33646171 PMID:33767344 PMID:34000440 PMID:34008892 PMID:34316023 PMID:34411415 PMID:34428338 PMID:34440373 PMID:34463354 PMID:34625927 PMID:34645488 PMID:34904211 PMID:35081925 PMID:35285867 PMID:35428369 PMID:35535697 PMID:35548885 PMID:35549722 PMID:35599849 PMID:35627144 PMID:35697689 PMID:36208971 PMID:36283893 PMID:36474027 PMID:36628841 PMID:37273706 PMID:37510298 PMID:37541188 PMID:37937776 More...
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NCBI chr 1:84,292,578...84,423,824
Ensembl chr 1:84,292,578...84,423,812
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G |
Gpt |
glutamic--pyruvic transaminase |
treatment |
IEP |
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RGD |
PMID:36495512 |
RGD:401717522 |
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
treatment |
IDA |
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RGD |
PMID:23762489 |
RGD:8695935 |
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Adm |
adrenomedullin |
treatment |
IEP ISO |
mRNA,protein:increased expression:liver,plasma: |
RGD |
PMID:19212187 PMID:19212187 |
RGD:7364958, RGD:7364958 |
NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
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G |
Ager |
advanced glycosylation end product-specific receptor |
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IEP |
mRNA:increased expression:liver |
RGD |
PMID:21431875 |
RGD:10402078 |
NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
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G |
Aldh2 |
aldehyde dehydrogenase 2 family member |
treatment |
ISO IEP |
protein:altered expression:liver (mouse) protein:altered expression:liver (rat) |
RGD |
PMID:30671488 PMID:29589772 |
RGD:15036807, RGD:14975297 |
NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
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G |
Atf6 |
activating transcription factor 6 |
ameliorates |
ISO |
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RGD |
PMID:34144219 |
RGD:329812011 |
NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
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G |
Atg13 |
autophagy related 13 |
ameliorates |
ISO |
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RGD |
PMID:34400126 |
RGD:329902072 |
NCBI chr 3:77,647,069...77,681,028
Ensembl chr 3:77,645,790...77,681,043
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G |
Atg16l1 |
autophagy related 16-like 1 |
ameliorates |
ISO |
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RGD |
PMID:34400126 |
RGD:329902072 |
NCBI chr 9:88,420,737...88,457,530
Ensembl chr 9:88,422,038...88,457,529
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G |
Atg4d |
autophagy related 4D, cysteine peptidase |
ameliorates |
ISO |
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RGD |
PMID:34400126 |
RGD:329902072 |
NCBI chr 8:19,807,733...19,817,321
Ensembl chr 8:19,807,766...19,817,321
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G |
Atg7 |
autophagy related 7 |
ameliorates |
ISO |
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RGD |
PMID:34400126 |
RGD:329902072 |
NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
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G |
Bad |
BCL2-associated agonist of cell death |
treatment |
IEP |
mRNA:increased expression:liver associated with Non-alcoholic Fatty Liver Disease |
RGD |
PMID:22647552 PMID:22847887 |
RGD:10053673, RGD:10053710 |
NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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G |
Bax |
BCL2 associated X, apoptosis regulator |
ameliorates treatment |
IEP ISO |
mRNA:increased expression:liver associated with Non-alcoholic Fatty Liver Disease |
RGD |
PMID:22647552 PMID:34144219 PMID:21092002 PMID:22847887 |
RGD:10053673, RGD:329812011, RGD:5134995, RGD:10053710 |
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
treatment ameliorates |
IDA ISO IEP |
associated with Non-alcoholic Fatty Liver Disease |
RGD |
PMID:22847887 PMID:34144219 PMID:21092002 |
RGD:10053710, RGD:329812011, RGD:5134995 |
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2l1 |
Bcl2-like 1 |
treatment |
IEP |
associated with Non-alcoholic Fatty Liver Disease |
RGD |
PMID:22847887 |
RGD:10053710 |
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 Ensembl chr 1:141,253,523...141,303,479
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G |
Becn1 |
beclin 1 |
ameliorates |
ISO |
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RGD |
PMID:34400126 |
RGD:329902072 |
NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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G |
Bid |
BH3 interacting domain death agonist |
ameliorates |
IMP |
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RGD |
PMID:17893612 |
RGD:408346749 |
NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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G |
C3 |
complement C3 |
treatment |
IEP |
|
RGD |
PMID:19854450 |
RGD:11040888 |
NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
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G |
Casp12 |
caspase 12 |
treatment |
IEP |
|
RGD |
PMID:29428101 |
RGD:13782166 |
NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
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G |
Casp3 |
caspase 3 |
ameliorates |
ISO |
|
RGD |
PMID:34144219 |
RGD:329812011 |
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp8 |
caspase 8 |
treatment |
IEP ISO |
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RGD |
PMID:23423194 PMID:15300206 |
RGD:8661760, RGD:14695087 |
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
treatment ameliorates |
IEP ISO |
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RGD |
PMID:23364428 PMID:34144219 |
RGD:13782358, RGD:329812011 |
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
ameliorates treatment severity |
IEP ISO |
mRNA, protein:increased expression:liver, serum (rat) |
RGD |
PMID:9500701 PMID:34400126 PMID:10630515 PMID:27229110 |
RGD:8549627, RGD:329902072, RGD:14995929, RGD:14995460 |
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
treatment severity |
ISO |
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RGD |
PMID:28623253 PMID:28623253 |
RGD:14995305, RGD:14995305 |
NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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G |
Ccl7 |
C-C motif chemokine ligand 7 |
ameliorates |
ISO |
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RGD |
PMID:34400126 |
RGD:329902072 |
NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
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G |
Ccn1 |
cellular communication network factor 1 |
ameliorates |
ISO |
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RGD |
PMID:34144219 |
RGD:329812011 |
NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
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G |
Ccr1 |
C-C motif chemokine receptor 1 |
ameliorates |
ISO |
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RGD |
PMID:34400126 |
RGD:329902072 |
NCBI chr 8:123,556,286...123,561,841
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G |
Ccr2 |
C-C motif chemokine receptor 2 |
severity |
ISO |
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RGD |
PMID:27229110 |
RGD:14995460 |
NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
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G |
Cd14 |
CD14 molecule |
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IDA |
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RGD |
PMID:22564590 |
RGD:7183676 |
NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
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G |
Cd40 |
CD40 molecule |
treatment |
IMP |
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RGD |
PMID:14741776 |
RGD:8547795 |
NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
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G |
Cfh |
complement factor H |
treatment |
IEP ISO |
mRNA,protein:decreased expression:liver,plasma: |
RGD |
PMID:19212187 PMID:19212187 |
RGD:7364958, RGD:7364958 |
NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838
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G |
Cs |
citrate synthase |
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IDA |
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RGD |
PMID:25416448 |
RGD:13504849 |
NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
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G |
Cst3 |
cystatin C |
ameliorates |
ISO |
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RGD |
PMID:34400126 |
RGD:329902072 |
NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
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G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
treatment ameliorates |
IDA ISO |
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RGD |
PMID:21092002 PMID:34400126 |
RGD:5134995, RGD:329902072 |
NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
treatment ameliorates |
ISO |
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RGD |
PMID:18041715 PMID:34400126 |
RGD:27095942, RGD:329902072 |
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
ameliorates |
ISO |
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RGD |
PMID:34400126 |
RGD:329902072 |
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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G |
Cxcl6 |
C-X-C motif chemokine ligand 6 |
ameliorates |
ISO |
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RGD |
PMID:34400126 |
RGD:329902072 |
NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093
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G |
Cxcl9 |
C-X-C motif chemokine ligand 9 |
ameliorates |
ISO |
|
RGD |
PMID:34400126 |
RGD:329902072 |
NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
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|
G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
|
IEP |
mRNA:decreased expression:lung |
RGD |
PMID:19595018 |
RGD:2314952 |
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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|
G |
Ddit3 |
DNA-damage inducible transcript 3 |
ameliorates |
ISO |
|
RGD |
PMID:34144219 |
RGD:329812011 |
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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|
G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
ameliorates |
ISO |
|
RGD |
PMID:34144219 |
RGD:329812011 |
NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
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|
G |
Elane |
elastase, neutrophil expressed |
|
IMP |
|
RGD |
PMID:10588515 |
RGD:10450560 |
NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100
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|
G |
Epo |
erythropoietin |
treatment |
ISO |
|
RGD |
PMID:25769561 |
RGD:15090809 |
NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
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|
G |
Epor |
erythropoietin receptor |
|
IEP |
protein:increased phosphorylation:liver: |
RGD |
PMID:25769561 |
RGD:15090809 |
NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257
|
|
G |
F3 |
coagulation factor III, tissue factor |
treatment |
IMP |
|
RGD |
PMID:11750579 |
RGD:11341708 |
NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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|
G |
Fadd |
Fas associated via death domain |
treatment |
IEP |
|
RGD |
PMID:23423194 |
RGD:8661760 |
NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
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|
G |
Fas |
Fas cell surface death receptor |
treatment |
IMP IEP |
protein:increased expression:liver |
RGD |
PMID:17235585 PMID:18561025 PMID:16222447 |
RGD:2290283, RGD:14700680, RGD:1600351 |
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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|
G |
Faslg |
Fas ligand |
treatment |
IMP |
|
RGD |
PMID:18561025 |
RGD:14700680 |
NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
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|
G |
Fga |
fibrinogen alpha chain |
|
IEP |
mRNA:increased expression:liver (rat) |
RGD |
PMID:23503399 |
RGD:9685021 |
NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528
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|
G |
Fn1 |
fibronectin 1 |
|
IDA |
|
RGD |
PMID:12651615 |
RGD:7205470 |
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
|
|
G |
Gpt |
glutamic--pyruvic transaminase |
treatment |
IEP |
|
RGD |
PMID:22564598 PMID:13678701 |
RGD:329970282, RGD:329970285 |
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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|
G |
Gsk3b |
glycogen synthase kinase 3 beta |
treatment |
IDA |
associated with nonalcoholic fatty liver disease |
RGD |
PMID:28807209 |
RGD:13792730 |
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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|
G |
Gstm1 |
glutathione S-transferase mu 1 |
|
IEP |
mRNA:decreased expression:lung |
RGD |
PMID:19595018 |
RGD:2314952 |
NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
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|
G |
H2ax |
H2A.X variant histone |
treatment |
IEP |
|
RGD |
PMID:23792534 |
RGD:8693718 |
NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 Ensembl chr 4:44,671,786...44,673,239
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|
G |
Hmgb1 |
high mobility group box 1 |
treatment |
IMP IEP |
protein:increased oxidation:liver mRNA, protein:increased expression, altered localization:serum, hepatocyte, cytoplasm |
RGD |
PMID:24578610 PMID:22514737 PMID:21431875 |
RGD:10402068, RGD:10402175, RGD:10402078 |
NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565 Ensembl chr16:5,901,586...5,978,565
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|
G |
Hmox1 |
heme oxygenase 1 |
treatment |
IEP |
|
RGD |
PMID:20446775 |
RGD:10755725 |
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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|
G |
Hp |
haptoglobin |
treatment |
IEP |
|
RGD |
PMID:17187421 PMID:21699906 |
RGD:1626366, RGD:11041815 |
NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
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|
G |
Icam1 |
intercellular adhesion molecule 1 |
treatment |
IMP IEP |
associated with Intestinal Reperfusion Injury;protein:increased expression:liver |
RGD |
PMID:7884306 PMID:8780571 |
RGD:11520784, RGD:14402044 |
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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|
G |
Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
severity |
ISO |
|
RGD |
PMID:28938192 |
RGD:14985248 |
NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
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|
G |
Ikbkg |
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma |
treatment |
IDA |
|
RGD |
PMID:22381173 |
RGD:12791280 |
NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499
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|
G |
Il10 |
interleukin 10 |
treatment |
IDA |
|
RGD |
PMID:21911118 |
RGD:7364839 |
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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|
G |
Il18 |
interleukin 18 |
treatment |
IEP ISO |
|
RGD |
PMID:25919765 PMID:14999688 |
RGD:14696667, RGD:14696668 |
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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|
G |
Il18bp |
interleukin 18 binding protein |
|
IEP |
mRNA,protein:increased expression:liver |
RGD |
PMID:25919765 |
RGD:14696667 |
NCBI chr 1:156,372,923...156,374,963
Ensembl chr 1:156,372,883...156,374,963
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|
G |
Il1a |
interleukin 1 alpha |
treatment |
IEP IDA |
mRNA:increased expression:lung protein:increased expression:serum |
RGD |
PMID:19595018 PMID:9840148 PMID:19283466 |
RGD:2314952, RGD:11059517, RGD:6907377 |
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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|
G |
Il1b |
interleukin 1 beta |
ameliorates treatment |
IDA ISO |
associated with Cholestasis |
RGD |
PMID:21468628 PMID:34400126 PMID:32155285 |
RGD:7175318, RGD:329902072, RGD:155260323 |
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il1rn |
interleukin 1 receptor antagonist |
treatment |
ISO IMP |
rat model treated with human protein |
RGD |
PMID:9000676 PMID:12451245 |
RGD:6909138, RGD:8551710 |
NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
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G |
Il6 |
interleukin 6 |
treatment ameliorates |
IDA ISO |
|
RGD |
PMID:24752458 PMID:34400126 PMID:34144219 PMID:32155285 |
RGD:11062134, RGD:329902072, RGD:329812011, RGD:155260323 |
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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|
G |
Irf8 |
interferon regulatory factor 8 |
ameliorates |
ISO |
|
RGD |
PMID:34400126 |
RGD:329902072 |
NCBI chr19:48,790,581...48,812,363
Ensembl chr19:48,790,588...48,811,829
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|
G |
Itgam |
integrin subunit alpha M |
treatment exacerbates |
IMP IEP |
protein:increased expression:neutrophil (rat) |
RGD |
PMID:8387952 PMID:11447039 |
RGD:329901847, RGD:329901849 |
NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
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|
G |
Jak2 |
Janus kinase 2 |
treatment |
IDA |
|
RGD |
PMID:22288937 |
RGD:10403073 |
NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
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|
G |
Lamp2 |
lysosomal-associated membrane protein 2 |
ameliorates |
ISO |
|
RGD |
PMID:34400126 |
RGD:329902072 |
NCBI chr X:117,173,097...117,222,090
Ensembl chr X:117,057,606...117,260,522
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|
G |
Lbp |
lipopolysaccharide binding protein |
|
IEP |
mRNA, protein:increased expression:liver |
RGD |
PMID:12134092 |
RGD:9685192 |
NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586
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|
G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
ameliorates |
ISO |
|
RGD |
PMID:34400126 |
RGD:329902072 |
NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 Ensembl chr16:49,665,791...49,677,690
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G |
Map3k7 |
mitogen activated protein kinase kinase kinase 7 |
ameliorates exacerbates |
ISO |
protein:increased phosphorylation:liver (mouse) |
RGD |
PMID:30076625 PMID:30622220 |
RGD:155804280, RGD:155882441 |
NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
|
IEP |
protein:increased activity:liver: |
RGD |
PMID:11679968 |
RGD:10412680 |
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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G |
Mfn2 |
mitofusin 2 |
treatment |
IEP |
mRNA, protein:decreased expression:liver (rat) |
RGD |
PMID:27363631 PMID:24898700 |
RGD:12910833, RGD:13204829 |
NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
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G |
Mir145 |
microRNA 145 |
|
IEP |
mRNA:decreased expression:small intestine (rat) |
RGD |
PMID:23166305 |
RGD:155230822 |
NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727
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G |
Mir155 |
microRNA 155 |
|
ISO |
|
RGD |
PMID:28640790 |
RGD:21079442 |
NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
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|
G |
Mir21 |
microRNA 21 |
|
IEP |
RNA:increased expression:liver |
RGD |
PMID:29187695 |
RGD:41410824 |
NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
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G |
Mir210 |
microRNA 210 |
treatment |
ISO |
|
RGD |
PMID:32155285 |
RGD:155260323 |
NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454
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G |
Mir223 |
microRNA 223 |
|
ISO |
RNA:increased expression:liver RNA:increased expression:serum,liver |
RGD |
PMID:19104939 PMID:28646120 |
RGD:13831297, RGD:21408574 |
NCBI chr X:61,141,887...61,141,996
Ensembl chr X:61,141,887...61,141,996
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G |
Mir34a |
microRNA 34a |
|
IEP |
miRNA:increased expression:liver |
RGD |
PMID:28963950 |
RGD:14695005 |
NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103
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G |
Mmp15 |
matrix metallopeptidase 15 |
|
IEP |
mRNA:increased expression:lung |
RGD |
PMID:19595018 |
RGD:2314952 |
NCBI chr19:9,663,449...9,684,943
Ensembl chr19:9,663,449...9,684,943
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G |
Mmp9 |
matrix metallopeptidase 9 |
treatment |
IEP |
associated with Fatty Liver;mRNA, protein:decreased expression, decreased activity:liver |
RGD |
PMID:17255325 |
RGD:8547976 |
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Muc1 |
mucin 1, cell surface associated |
|
IEP |
mRNA, protein:decreased expression:bile duct |
RGD |
PMID:21775928 |
RGD:7364757 |
NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733
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G |
Muc17 |
mucin 17, cell surface associated |
|
IEP |
mRNA, protein:decreased expression:bile duct |
RGD |
PMID:21775928 |
RGD:7364757 |
NCBI chr12:19,527,251...19,536,924
Ensembl chr12:19,527,321...19,538,522
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G |
Muc4 |
mucin 4, cell surface associated |
|
IEP |
mRNA:decreased expression:bile duct |
RGD |
PMID:21775928 |
RGD:7364757 |
NCBI chr11:68,008,245...68,053,242
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G |
Nfatc1 |
nuclear factor of activated T-cells 1 |
|
ISO |
mRNA,protein:increased expression:liver: |
RGD |
PMID:36092961 |
RGD:268357360 |
NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
treatment |
IEP |
|
RGD |
PMID:22288937 PMID:31952110 |
RGD:10403073, RGD:21201304 |
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Nos3 |
nitric oxide synthase 3 |
treatment |
IEP |
|
RGD |
PMID:28966130 |
RGD:13450941 |
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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G |
Pf4 |
platelet factor 4 |
exacerbates |
ISO |
|
RGD |
PMID:25440775 |
RGD:329901829 |
NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365
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|
G |
Proc |
protein C, inactivator of coagulation factors Va and VIIIa |
treatment |
ISO |
|
RGD |
PMID:12605111 PMID:18507760 |
RGD:11100021, RGD:11100046 |
NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133
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G |
Rab10 |
RAB10, member RAS oncogene family |
ameliorates |
ISO |
|
RGD |
PMID:34400126 |
RGD:329902072 |
NCBI chr 6:26,267,081...26,319,739
Ensembl chr 6:26,266,859...26,320,193
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|
G |
Rab8b |
RAB8B, member RAS oncogene family |
ameliorates |
ISO |
|
RGD |
PMID:34400126 |
RGD:329902072 |
NCBI chr 8:67,458,921...67,536,466
Ensembl chr 8:67,458,923...67,536,384
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G |
Selplg |
selectin P ligand |
ameliorates |
IMP |
|
RGD |
PMID:16365457 |
RGD:401717523 |
NCBI chr12:42,796,690...42,809,908
Ensembl chr12:42,796,580...42,812,585
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G |
Serpinc1 |
serpin family C member 1 |
treatment |
IEP ISO |
|
RGD |
PMID:24726586 PMID:8589354 |
RGD:10450597, RGD:11038771 |
NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293
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G |
Serpine1 |
serpin family E member 1 |
|
IEP |
protein:increased activity:plasma (rat) |
RGD |
PMID:12353078 |
RGD:8547901 |
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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G |
Serping1 |
serpin family G member 1 |
treatment |
ISO |
|
RGD |
PMID:16367929 |
RGD:1580273 |
NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034
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G |
Sirt1 |
sirtuin 1 |
treatment |
IEP |
|
RGD |
PMID:24557422 |
RGD:9497542 |
NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
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G |
Slpi |
secretory leukocyte peptidase inhibitor |
|
IEP |
|
RGD |
PMID:19595018 |
RGD:2314952 |
NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
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|
G |
Sod1 |
superoxide dismutase 1 |
treatment |
ISO |
human gene in a rat model |
RGD |
PMID:16555330 PMID:11779401 |
RGD:8655889, RGD:1581095 |
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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|
G |
Sod3 |
superoxide dismutase 3 |
treatment |
ISO |
human gene in a rat model |
RGD |
PMID:11779401 |
RGD:1581095 |
NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
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|
G |
Tert |
telomerase reverse transcriptase |
treatment |
ISO |
|
RGD |
PMID:19545665 |
RGD:11038676 |
NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561
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G |
Tfpi |
tissue factor pathway inhibitor |
|
ISO |
|
RGD |
PMID:9921794 |
RGD:11062061 |
NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880
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|
G |
Tlr2 |
toll-like receptor 2 |
treatment |
ISO IEP |
|
RGD |
PMID:16038046 PMID:25769561 |
RGD:15090805, RGD:15090809 |
NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
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|
G |
Tlr4 |
toll-like receptor 4 |
treatment severity |
IEP ISO |
mRNA:increased expression:liver protein:increased expression:membrane raft: |
RGD |
PMID:21431875 PMID:21693218 PMID:22797797 PMID:23395256 PMID:27064547 |
RGD:10402078, RGD:5685379, RGD:14697702, RGD:14697699, RGD:14697698 |
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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G |
Tnf |
tumor necrosis factor |
treatment |
IEP IMP ISO |
protein:increased expression:serum (rat) |
RGD |
PMID:24726586 PMID:12131680 PMID:32155285 PMID:11592783 PMID:19357028 PMID:11129814 PMID:21125813 PMID:10454827 PMID:15457564 PMID:17164725 More...
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RGD:10450597, RGD:14995454, RGD:155260323, RGD:2325259, RGD:15039406, RGD:14995473, RGD:14995447, RGD:14985258, RGD:14985257, RGD:14696803 |
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tnfrsf1a |
TNF receptor superfamily member 1A |
|
IEP |
protein:increased localization:mitochondrion |
RGD |
PMID:23423194 |
RGD:8661760 |
NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
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|
G |
Tradd |
TNFRSF1A-associated via death domain |
treatment |
IEP |
|
RGD |
PMID:23423194 |
RGD:8661760 |
NCBI chr19:33,136,148...33,142,714
Ensembl chr19:33,136,138...33,142,638
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G |
Ucp2 |
uncoupling protein 2 |
|
IEP |
mRNA:increased expression:liver |
RGD |
PMID:22195248 |
RGD:7175309 |
NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
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G |
Vegfa |
vascular endothelial growth factor A |
|
IEP |
|
RGD |
PMID:26451003 |
RGD:15036791 |
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Xdh |
xanthine dehydrogenase |
treatment |
IEP |
|
RGD |
PMID:24768926 |
RGD:13209011 |
NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
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G |
Bax |
BCL2 associated X, apoptosis regulator |
treatment ameliorates |
IEP ISO |
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RGD |
PMID:23953793 PMID:34238924 |
RGD:10054119, RGD:153350155 |
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
treatment |
IEP |
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RGD |
PMID:23953793 |
RGD:10054119 |
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Casp3 |
caspase 3 |
treatment |
IEP |
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RGD |
PMID:23953793 |
RGD:10054119 |
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Col1a1 |
collagen type I alpha 1 chain |
|
ISO |
mRNA:increased expression:lung (mouse) |
RGD |
PMID:34238924 |
RGD:153350155 |
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Col3a1 |
collagen type III alpha 1 chain |
|
ISO |
mRNA:increased expression:lung (mouse) |
RGD |
PMID:34238924 |
RGD:153350155 |
NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
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G |
Crebbp |
CREB binding protein |
ameliorates |
ISO |
|
RGD |
PMID:34238924 |
RGD:153350155 |
NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
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G |
Egr1 |
early growth response 1 |
treatment |
IMP IEP |
|
RGD |
PMID:22878149 PMID:23232597 |
RGD:10395282, RGD:10395299 |
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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G |
Elane |
elastase, neutrophil expressed |
treatment |
IMP |
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RGD |
PMID:17888675 |
RGD:10450582 |
NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100
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G |
Fgfr2 |
fibroblast growth factor receptor 2 |
|
ISO |
mRNA:increased expression:lung (rat) |
RGD |
PMID:35600952 |
RGD:155663563 |
NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
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G |
Hmgb1 |
high mobility group box 1 |
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IEP |
protein:increased expression:lung |
RGD |
PMID:22115333 |
RGD:10402095 |
NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565 Ensembl chr16:5,901,586...5,978,565
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G |
Hmox1 |
heme oxygenase 1 |
|
IEP |
protein:increased expression:lung |
RGD |
PMID:21227458 |
RGD:10755577 |
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Icam1 |
intercellular adhesion molecule 1 |
treatment |
IEP |
|
RGD |
PMID:22503847 |
RGD:7240537 |
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Il1b |
interleukin 1 beta |
ameliorates |
IDA ISO IEP |
protein:increased expression:lung (rat) |
RGD |
PMID:23142117 PMID:34238924 PMID:23122581 |
RGD:7183185, RGD:153350155, RGD:7204125 |
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il4 |
interleukin 4 |
treatment |
IDA |
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RGD |
PMID:24365768 |
RGD:10402797 |
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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G |
Il6 |
interleukin 6 |
ameliorates |
ISO |
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RGD |
PMID:34238924 |
RGD:153350155 |
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Kras |
KRAS proto-oncogene, GTPase |
ameliorates |
ISO |
|
RGD |
PMID:34238924 |
RGD:153350155 |
NCBI chr 4:178,185,418...178,218,484
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G |
Mmp9 |
matrix metallopeptidase 9 |
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IEP |
protein:increased activity:lung |
RGD |
PMID:18694576 |
RGD:5129703 |
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
treatment |
IEP |
|
RGD |
PMID:22503847 |
RGD:7240537 |
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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G |
Nos3 |
nitric oxide synthase 3 |
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IMP ISO |
mRNA:increased expression:lung (mouse) |
RGD |
PMID:20815765 PMID:25382268 |
RGD:4892012, RGD:11533932 |
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
treatment |
IEP |
|
RGD |
PMID:21781312 |
RGD:6771212 |
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Pecam1 |
platelet and endothelial cell adhesion molecule 1 |
|
IDA IEP |
protein:increased expression:alveolar macrophage (rat) |
RGD |
PMID:21781312 PMID:16449942 |
RGD:6771212, RGD:11541083 |
NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
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G |
Proc |
protein C, inactivator of coagulation factors Va and VIIIa |
treatment |
ISO |
|
RGD |
PMID:19782612 |
RGD:11100035 |
NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133
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G |
Serpine1 |
serpin family E member 1 |
treatment |
ISO IDA |
protein:increased expression:plasma (human) |
RGD |
PMID:17846288 PMID:11606484 |
RGD:8547720, RGD:11080966 |
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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G |
Tlr4 |
toll-like receptor 4 |
treatment |
IEP |
|
RGD |
PMID:22115333 |
RGD:10402095 |
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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G |
Tnf |
tumor necrosis factor |
ameliorates |
IMP ISO |
|
RGD |
PMID:17294835 PMID:34238924 |
RGD:4143397, RGD:153350155 |
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Zfp36 |
zinc finger protein 36 |
exacerbates |
ISO |
|
RGD |
PMID:34238924 |
RGD:153350155 |
NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
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G |
Cacna1s |
calcium voltage-gated channel subunit alpha1 S |
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ISO |
ClinVar Annotator: match by term: Pharmacogenic myopathy |
ClinVar |
PMID:20861472 PMID:24033266 PMID:24055113 PMID:24195946 PMID:24784157 PMID:25637381 PMID:25735680 PMID:25741868 PMID:26332594 PMID:26467025 PMID:27147545 PMID:28011884 PMID:28492532 PMID:29193480 PMID:29212769 More...
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NCBI chr13:47,493,949...47,564,194
Ensembl chr13:47,493,949...47,564,318
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G |
Ryr1 |
ryanodine receptor 1 |
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ISO |
ClinVar Annotator: match by term: Pharmacogenic myopathy ClinVar Annotator: match by term: Fulminating hyperpyrexia | ClinVar Annotator: match by term: Pharmacogenic myopathy |
ClinVar |
PMID:12434 PMID:16940 PMID:18253 PMID:18564 PMID:1256913 PMID:1329581 PMID:1354642 PMID:1510267 PMID:1639409 PMID:1743490 PMID:1774073 PMID:1774074 PMID:1810122 PMID:1862346 PMID:2047609 PMID:2842332 PMID:3356401 PMID:3626847 PMID:4149045 PMID:6917943 PMID:7299413 PMID:7511586 PMID:7547049 PMID:7554356 PMID:7586638 PMID:7633940 PMID:7751854 PMID:7762556 PMID:7829078 PMID:7849712 PMID:7881417 PMID:7889656 PMID:8010475 PMID:8012359 PMID:8220422 PMID:8220423 PMID:8401544 PMID:8592342 PMID:8602662 PMID:8661021 PMID:8825043 PMID:8828983 PMID:9030597 PMID:9066328 PMID:9106529 PMID:9138151 PMID:9199552 PMID:9334205 PMID:9389851 PMID:9450902 PMID:9497245 PMID:9520251 PMID:9536098 PMID:9543323 PMID:9831351 PMID:9873004 PMID:10051009 PMID:10097181 PMID:10352931 PMID:10484775 PMID:10612851 PMID:10700782 PMID:10756965 PMID:10793526 PMID:10823104 PMID:10888602 PMID:11063719 PMID:11135728 PMID:11274444 PMID:11448278 PMID:11493496 PMID:11524458 PMID:11525881 PMID:11553045 PMID:11575529 PMID:11668625 PMID:11673462 PMID:11709545 PMID:11741831 PMID:11873057 PMID:11928716 PMID:12059893 PMID:12066726 PMID:12123492 PMID:12124989 PMID:12136074 PMID:12151923 PMID:12208234 PMID:12220451 PMID:12237752 PMID:12411786 PMID:12411788 PMID:12434264 PMID:12467748 PMID:12565913 PMID:12642598 PMID:12700608 PMID:12709367 PMID:12732639 PMID:12883402 PMID:12937085 PMID:14500992 PMID:14641996 PMID:14670767 PMID:14708096 PMID:14732627 PMID:14985404 PMID:14999498 PMID:15108991 PMID:15175001 PMID:15210166 PMID:15221887 PMID:15281512 PMID:15299003 PMID:15347586 PMID:15448513 PMID:15731587 PMID:16084090 PMID:16163667 PMID:16199547 PMID:16244001 PMID:16272262 PMID:16284304 PMID:16372898 PMID:16380615 PMID:16521288 PMID:16621918 PMID:16732084 PMID:16732090 PMID:16732128 PMID:16835904 PMID:16917943 PMID:16940308 PMID:16958617 PMID:17033962 PMID:17081125 PMID:17081152 PMID:17122579 PMID:17204054 PMID:17204937 PMID:17226826 PMID:17365175 PMID:17483490 PMID:17538032 PMID:17576681 PMID:17667581 PMID:17667681 PMID:17710899 PMID:17968765 PMID:18063506 PMID:18171678 PMID:18193641 PMID:18212565 PMID:18253926 PMID:18306019 PMID:18414213 PMID:18502356 PMID:18505122 PMID:18564801 PMID:18719443 PMID:18765655 PMID:18813041 PMID:18945287 PMID:19015156 PMID:19020143 PMID:19027160 PMID:19191329 PMID:19191333 PMID:19223216 PMID:19346234 PMID:19454545 PMID:19513315 PMID:19541610 PMID:19645060 PMID:19648156 PMID:19658156 PMID:19685112 PMID:19797833 PMID:19807743 PMID:19825159 PMID:19919814 PMID:19931341 PMID:20080402 PMID:20142353 PMID:20301325 PMID:20301436 PMID:20301565 PMID:20439600 PMID:20461000 PMID:20566647 PMID:20583297 PMID:20681998 PMID:20839240 PMID:20888934 PMID:20952238 PMID:20981092 PMID:21062345 PMID:21118704 PMID:21156754 PMID:21157159 PMID:21282829 PMID:21455645 PMID:21503806 PMID:21514828 PMID:21674524 PMID:21795085 PMID:21804810 PMID:21825032 PMID:21878807 PMID:21911697 PMID:21918424 PMID:21965348 PMID:22030266 PMID:22203976 PMID:22407809 PMID:22415532 PMID:22418739 PMID:22473935 PMID:22526018 PMID:22696611 PMID:22705209 PMID:22734812 PMID:22851008 PMID:22913516 PMID:22992668 PMID:22995991 PMID:23035052 PMID:23069638 PMID:23127960 PMID:23159934 PMID:23183335 PMID:23204524 PMID:23308296 PMID:23329375 PMID:23394784 PMID:23422674 PMID:23459219 PMID:23460944 PMID:23476141 PMID:23478172 PMID:23553484 PMID:23553787 PMID:23558838 PMID:23628358 PMID:23736090 PMID:23826317 PMID:23842196 PMID:23919265 PMID:24013571 PMID:24033266 PMID:24053352 PMID:24055113 PMID:24088041 PMID:24091937 PMID:24195946 PMID:24215330 PMID:24319099 PMID:24361844 PMID:24433488 PMID:24561095 PMID:24627108 PMID:24950660 PMID:24951453 PMID:24961629 PMID:25084811 PMID:25086907 PMID:25214167 PMID:25256590 PMID:25268394 PMID:25326635 PMID:25428687 PMID:25461839 PMID:25466363 PMID:25476234 PMID:25517095 PMID:25521991 PMID:25525159 PMID:25558065 PMID:25611019 PMID:25614869 PMID:25635128 PMID:25637381 PMID:25658027 PMID:25683120 PMID:25735680 PMID:25741868 PMID:25747005 PMID:25749300 PMID:25957634 PMID:25958340 PMID:25960145 PMID:25985138 PMID:25987458 PMID:25989378 PMID:26019235 PMID:26068069 PMID:26115329 PMID:26275793 PMID:26332594 PMID:26381711 PMID:26467025 PMID:26565425 PMID:26578207 PMID:26633545 PMID:26841830 PMID:26951757 PMID:26994242 PMID:27005958 PMID:27058611 PMID:27066551 PMID:27147545 PMID:27153395 PMID:27159402 PMID:27234031 PMID:27353517 PMID:27363342 PMID:27382027 PMID:27431030 PMID:27447704 PMID:27452334 PMID:27545679 PMID:27555149 PMID:27558158 PMID:27586648 PMID:27616680 PMID:27646467 PMID:27663056 PMID:27708273 PMID:27831900 PMID:27854218 PMID:27857962 PMID:27918309 PMID:28003660 PMID:28007021 PMID:28063098 PMID:28078069 PMID:28166811 PMID:28224104 PMID:28259615 PMID:28269792 PMID:28290972 PMID:28325813 PMID:28326467 PMID:28357410 PMID:28403410 PMID:28424332 PMID:28492532 PMID:28496993 PMID:28527222 PMID:28687594 PMID:28750945 PMID:28818389 PMID:29028638 PMID:29096039 PMID:29169929 PMID:29172004 PMID:29178655 PMID:29261186 PMID:29298851 PMID:29344738 PMID:29355282 PMID:29382405 PMID:29417091 PMID:29576327 PMID:29608462 PMID:29629541 PMID:29635721 PMID:29667327 PMID:29701772 PMID:29792937 PMID:29802573 PMID:30115273 PMID:30122538 PMID:30155738 PMID:30236257 PMID:30236258 PMID:30291343 PMID:30325262 PMID:30406384 PMID:30499100 PMID:30609409 PMID:30611313 PMID:30652412 PMID:30724636 PMID:30755392 PMID:30788618 PMID:30827497 PMID:30842289 PMID:30864471 PMID:30872186 PMID:30916033 PMID:31016048 PMID:31055738 PMID:31068157 PMID:31107960 PMID:31127727 PMID:31130284 PMID:31135626 PMID:31165076 PMID:31206373 PMID:31301762 PMID:31304636 PMID:31321302 PMID:31395954 PMID:31407473 PMID:31447099 PMID:31517061 PMID:31559918 PMID:31589614 PMID:31618753 PMID:31680123 PMID:31680349 PMID:31742715 PMID:31841587 PMID:31851124 PMID:31903994 PMID:31994743 PMID:32054689 PMID:32098966 PMID:32236737 PMID:32304219 PMID:32371413 PMID:32403337 PMID:32461654 PMID:32528171 PMID:32600061 PMID:32665702 PMID:32861507 PMID:32899693 PMID:32978841 PMID:33037202 PMID:33060286 PMID:33146414 PMID:33176865 PMID:33190635 PMID:33258288 PMID:33259453 PMID:33333461 PMID:33458582 PMID:33490280 PMID:33564012 PMID:33625594 PMID:33646171 PMID:33726816 PMID:33758288 PMID:33767344 PMID:34000440 PMID:34008892 PMID:34106991 PMID:34127251 PMID:34316023 PMID:34411415 PMID:34426522 PMID:34428338 PMID:34440373 PMID:34463354 PMID:34535181 PMID:34595679 PMID:34625927 PMID:34645488 PMID:34809703 PMID:34904211 PMID:35081925 PMID:35285867 PMID:35361824 PMID:35387801 PMID:35428369 PMID:35535697 PMID:35548885 PMID:35549722 PMID:35599849 PMID:35627144 PMID:35666680 PMID:35693006 PMID:35697689 PMID:35846108 PMID:35849058 PMID:36100962 PMID:36208971 PMID:36283893 PMID:36474027 PMID:36628841 PMID:37273706 PMID:37510298 PMID:37541188 PMID:37712079 PMID:37937776 PMID:39033378 More...
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NCBI chr 1:84,292,578...84,423,824
Ensembl chr 1:84,292,578...84,423,812
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G |
Asph |
aspartate-beta-hydroxylase |
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ISO |
ClinVar Annotator: match by term: Exercise-induced malignant hyperthermia | ClinVar Annotator: match by term: Malignant hyperthermia of anesthesia |
ClinVar |
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NCBI chr 5:22,601,581...22,814,107
Ensembl chr 5:22,603,486...22,813,876
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G |
Cacna1s |
calcium voltage-gated channel subunit alpha1 S |
susceptibility |
ISO |
DNA,protein:missense mutation:cds:p.R1086H (human) ClinVar Annotator: match by term: Anesthesia related hyperthermia | ClinVar Annotator: match by term: Malignant hyperpyrexia | ClinVar Annotator: match by term: Malignant hyperpyrexia susceptibility type 5 | ClinVar Annotator: match by term: Malignant hyperthermia of anesthesia | ClinVar Annotator: match by term: Malignant hyperthermia susceptibility | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 1 | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 5 ClinVar Annotator: match by term: Exercise-induced malignant hyperthermia | ClinVar Annotator: match by term: Malignant hyperpyrexia | ClinVar Annotator: match by term: Malignant hyperpyrexia susceptibility type 5 | ClinVar Annotator: match by term: Malignant hyperthermia of anesthesia | ClinVar Annotator: match by term: Malignant hyperthermia susceptibility | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 1 | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 5 ClinVar Annotator: match by term: Anesthesia related hyperthermia | ClinVar Annotator: match by term: Malignant hyperpyrexia | ClinVar Annotator: match by term: Malignant hyperpyrexia susceptibility type 5 | ClinVar Annotator: match by term: Malignant hyperthermia of anesthesia | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 1 | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 5 CTD Direct Evidence: marker/mechanism ClinVar Annotator: match by term: Malignant hyperpyrexia | ClinVar Annotator: match by term: Malignant hyperpyrexia susceptibility type 5 | ClinVar Annotator: match by term: Malignant hyperthermia | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 5 ClinVar Annotator: match by term: Hyperpyrexia, malignant | ClinVar Annotator: match by term: Malignant hyperpyrexia susceptibility type 5 | ClinVar Annotator: match by term: Malignant hyperthermia | ClinVar Annotator: match by term: Malignant hyperthermia susceptibility | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 5 |
OMIM ClinVar CTD RGD |
PMID:1982519 PMID:3037387 PMID:7650604 PMID:7847370 PMID:7897626 PMID:7987325 PMID:8004673 PMID:8605978 PMID:9066893 PMID:9132138 PMID:9199552 PMID:9512357 PMID:9536098 PMID:9852570 PMID:10074484 PMID:10523403 PMID:10590402 PMID:10639629 PMID:11034874 PMID:11260227 PMID:11328898 PMID:11353725 PMID:11555352 PMID:11591859 PMID:11808349 PMID:11940049 PMID:12411788 PMID:15098604 PMID:15201141 PMID:15711422 PMID:15716625 PMID:15726306 PMID:16163667 PMID:16199547 PMID:17418573 PMID:17576681 PMID:17587224 PMID:18162704 PMID:18229654 PMID:18325191 PMID:18835861 PMID:19118277 PMID:19225109 PMID:19822448 PMID:19825159 PMID:20213496 PMID:20301512 PMID:20431982 PMID:20861472 PMID:21841462 PMID:22547813 PMID:22901280 PMID:22992668 PMID:23019082 PMID:23187123 PMID:23662824 PMID:23663834 PMID:24013571 PMID:24033266 PMID:24055113 PMID:24195946 PMID:24433488 PMID:24784157 PMID:25132214 PMID:25213595 PMID:25430699 PMID:25637381 PMID:25658027 PMID:25735680 PMID:25741868 PMID:26188342 PMID:26247046 PMID:26252573 PMID:26332594 PMID:26467025 PMID:26994242 PMID:27147545 PMID:28008999 PMID:28011884 PMID:28012042 PMID:28166811 PMID:28259615 PMID:28325641 PMID:28326467 PMID:28492532 PMID:28686619 PMID:28779239 PMID:28857175 PMID:28972032 PMID:29193480 PMID:29212769 PMID:29572832 PMID:29792937 PMID:30090141 PMID:30236257 PMID:30325262 PMID:31068157 PMID:31227654 PMID:31380823 PMID:31447099 PMID:31567646 PMID:31851124 PMID:33042247 PMID:33060286 PMID:33184660 PMID:33564012 PMID:33667896 PMID:34008892 PMID:34440373 PMID:34608571 PMID:34777470 PMID:34804722 PMID:35509735 PMID:9199552 More...
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RGD:1300373 |
NCBI chr13:47,493,949...47,564,194
Ensembl chr13:47,493,949...47,564,318
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G |
Cacng1 |
calcium voltage-gated channel auxiliary subunit gamma 1 |
|
ISO |
|
RGD |
PMID:8395940 |
RGD:734675 |
NCBI chr10:92,652,924...92,665,612
Ensembl chr10:92,652,614...92,665,783
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G |
Casq1 |
calsequestrin 1 |
|
ISO |
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RGD |
PMID:19237502 |
RGD:329813080 |
NCBI chr13:84,670,648...84,680,339
Ensembl chr13:84,670,649...84,680,339
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G |
Ryr1 |
ryanodine receptor 1 |
treatment |
ISO ISS |
CTD Direct Evidence: marker/mechanism ClinVar Annotator: match by term: Anesthesia related hyperthermia | ClinVar Annotator: match by term: Malignant hyperpyrexia | ClinVar Annotator: match by term: Malignant hyperpyrexia susceptibility type 5 | ClinVar Annotator: match by term: Malignant hyperthermia of anesthesia | ClinVar Annotator: match by term: Malignant hyperthermia susceptibility | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 1 | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 5 ClinVar Annotator: match by term: Anesthesia related hyperthermia | ClinVar Annotator: match by term: Malignant hyperpyrexia | ClinVar Annotator: match by term: Malignant hyperthermia of anesthesia | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 1 | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 5 ClinVar Annotator: match by term: Anesthesia related hyperthermia | ClinVar Annotator: match by term: Malignant hyperpyrexia | ClinVar Annotator: match by term: Malignant hyperpyrexia susceptibility type 5 | ClinVar Annotator: match by term: Malignant hyperthermia of anesthesia | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 1 | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 5 ClinVar Annotator: match by term: Anesthesia related hyperthermia | ClinVar Annotator: match by term: Exercise-induced malignant hyperthermia | ClinVar Annotator: match by term: Malignant hyperpyrexia | ClinVar Annotator: match by term: Malignant hyperthermia of anesthesia | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 1 | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 5 ClinVar Annotator: match by term: Anesthesia related hyperthermia | ClinVar Annotator: match by term: Hyperpyrexia, malignant | ClinVar Annotator: match by term: Malignant hyperpyrexia | ClinVar Annotator: match by term: Malignant hyperthermia | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 1 ClinVar Annotator: match by term: Anesthesia related hyperthermia | ClinVar Annotator: match by term: Exercise-induced malignant hyperthermia | ClinVar Annotator: match by term: Hyperpyrexia, malignant | ClinVar Annotator: match by term: Malignant hyperpyrexia | ClinVar Annotator: match by term: Malignant hyperthermia | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 1 | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 5 ClinVar Annotator: match by term: Anesthesia related hyperthermia | ClinVar Annotator: match by term: Malignant hyperpyrexia | ClinVar Annotator: match by term: Malignant hyperthermia | ClinVar Annotator: match by term: Malignant hyperthermia susceptibility | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 1 ClinVar Annotator: match by term: Anesthesia related hyperthermia | ClinVar Annotator: match by term: Hyperpyrexia, malignant | ClinVar Annotator: match by term: Malignant hyperpyrexia | ClinVar Annotator: match by term: Malignant hyperthermia | ClinVar Annotator: match by term: Malignant hyperthermia susceptibility | ClinVar Annotator: match by term: Malignant hyperthermia, susceptibility to, 1 |
CTD OMIM ClinVar MouseDO RGD |
PMID:12434 PMID:16940 PMID:18253 PMID:18564 PMID:1256913 PMID:1329581 PMID:1354642 PMID:1510267 PMID:1639409 PMID:1743490 PMID:1774073 PMID:1774074 PMID:1810122 PMID:1862346 PMID:2047609 PMID:2842332 PMID:3356401 PMID:3626847 PMID:4149045 PMID:6917943 PMID:7299413 PMID:7511586 PMID:7547049 PMID:7554356 PMID:7586638 PMID:7633940 PMID:7751854 PMID:7762556 PMID:7829078 PMID:7849712 PMID:7881417 PMID:7889656 PMID:8010475 PMID:8012359 PMID:8220422 PMID:8220423 PMID:8401544 PMID:8592342 PMID:8602662 PMID:8661021 PMID:8825043 PMID:8828983 PMID:9030597 PMID:9066328 PMID:9106529 PMID:9138151 PMID:9199552 PMID:9334205 PMID:9389851 PMID:9450902 PMID:9497245 PMID:9520251 PMID:9536098 PMID:9543323 PMID:9831351 PMID:9873004 PMID:10051009 PMID:10097181 PMID:10352931 PMID:10484775 PMID:10612851 PMID:10700782 PMID:10756965 PMID:10793526 PMID:10823104 PMID:10888602 PMID:11063719 PMID:11113224 PMID:11135728 PMID:11274444 PMID:11448278 PMID:11493496 PMID:11524458 PMID:11525881 PMID:11553045 PMID:11575529 PMID:11668625 PMID:11673462 PMID:11695996 PMID:11709545 PMID:11741831 PMID:11873057 PMID:11928716 PMID:12059893 PMID:12066726 PMID:12123492 PMID:12124989 PMID:12136074 PMID:12151923 PMID:12161072 PMID:12208234 PMID:12220451 PMID:12237752 PMID:12411786 PMID:12411788 PMID:12434264 PMID:12467748 PMID:12565913 PMID:12642598 PMID:12700608 PMID:12709367 PMID:12732639 PMID:12883402 PMID:12937085 PMID:14500992 PMID:14570802 PMID:14641996 PMID:14670767 PMID:14708096 PMID:14732627 PMID:14985404 PMID:14999498 PMID:15108991 PMID:15175001 PMID:15210166 PMID:15221887 PMID:15281512 PMID:15299003 PMID:15347586 PMID:15448513 PMID:15731587 PMID:16084090 PMID:16163667 PMID:16199547 PMID:16244001 PMID:16244682 PMID:16272262 PMID:16284304 PMID:16372898 PMID:16380615 PMID:16521288 PMID:16621918 PMID:16732080 PMID:16732084 PMID:16732090 PMID:16732128 PMID:16835904 PMID:16917943 PMID:16940308 PMID:16958617 PMID:17033962 PMID:17081125 PMID:17081152 PMID:17122579 PMID:17204054 PMID:17204937 PMID:17226826 PMID:17293538 PMID:17365175 PMID:17483490 PMID:17538032 PMID:17576681 PMID:17667581 PMID:17667681 PMID:17707769 PMID:17710899 PMID:17968765 PMID:18063506 PMID:18171678 PMID:18193641 PMID:18212565 PMID:18253926 PMID:18306019 PMID:18414213 PMID:18502356 PMID:18505122 PMID:18564801 PMID:18719443 PMID:18765655 PMID:18813041 PMID:18945287 PMID:19015156 PMID:19020143 PMID:19027160 PMID:19191329 PMID:19191333 PMID:19223216 PMID:19346234 PMID:19442771 PMID:19454545 PMID:19513315 PMID:19541610 PMID:19645060 PMID:19648156 PMID:19658156 PMID:19685112 PMID:19797833 PMID:19807743 PMID:19825159 PMID:19919814 PMID:19931341 PMID:20080402 PMID:20142353 PMID:20301325 PMID:20301436 PMID:20301565 PMID:20439600 PMID:20461000 PMID:20566647 PMID:20583297 PMID:20681998 PMID:20839240 PMID:20888934 PMID:20952238 PMID:20981092 PMID:21062345 PMID:21088110 PMID:21118704 PMID:21156754 PMID:21157159 PMID:21282829 PMID:21455645 PMID:21485675 PMID:21503806 PMID:21514828 PMID:21674524 PMID:21795085 PMID:21804810 PMID:21825032 PMID:21878807 PMID:21911697 PMID:21918424 PMID:21965348 PMID:22030266 PMID:22203976 PMID:22407809 PMID:22415532 PMID:22418739 PMID:22473935 PMID:22526018 PMID:22550088 PMID:22696611 PMID:22705209 PMID:22734812 PMID:22851008 PMID:22913516 PMID:22992668 PMID:22995991 PMID:23035052 PMID:23069638 PMID:23127960 PMID:23159934 PMID:23183335 PMID:23204524 PMID:23308296 PMID:23329375 PMID:23394784 PMID:23422674 PMID:23456818 PMID:23459219 PMID:23460944 PMID:23476141 PMID:23478172 PMID:23553484 PMID:23553787 PMID:23558838 PMID:23628358 PMID:23736090 PMID:23826317 PMID:23842196 PMID:23919265 PMID:24013571 PMID:24033266 PMID:24053352 PMID:24055113 PMID:24088041 PMID:24091937 PMID:24195946 PMID:24215330 PMID:24319099 PMID:24361844 PMID:24433488 PMID:24561095 PMID:24627108 PMID:24706162 PMID:24950660 PMID:24951453 PMID:24961629 PMID:25084811 PMID:25086907 PMID:25214167 PMID:25256590 PMID:25268394 PMID:25326635 PMID:25356970 PMID:25428687 PMID:25461839 PMID:25466363 PMID:25476234 PMID:25517095 PMID:25521991 PMID:25525159 PMID:25558065 PMID:25611019 PMID:25614869 PMID:25628744 PMID:25635128 PMID:25637381 PMID:25658027 PMID:25683120 PMID:25735680 PMID:25741868 PMID:25741909 PMID:25747005 PMID:25749300 PMID:25882082 PMID:25957634 PMID:25958340 PMID:25960145 PMID:25985138 PMID:25987458 PMID:25989378 PMID:26019235 PMID:26068069 PMID:26115329 PMID:26275793 PMID:26332594 PMID:26381711 PMID:26467025 PMID:26565425 PMID:26578207 PMID:26631338 PMID:26633545 PMID:26684984 PMID:26833332 PMID:26841830 PMID:26951757 PMID:26994242 PMID:27005958 PMID:27058611 PMID:27066551 PMID:27147545 PMID:27153395 PMID:27159402 PMID:27234031 PMID:27353517 PMID:27363342 PMID:27382027 PMID:27431030 PMID:27447704 PMID:27452334 PMID:27545679 PMID:27555149 PMID:27558158 PMID:27586648 PMID:27616680 PMID:27646467 PMID:27663056 PMID:27708273 PMID:27831900 PMID:27854218 PMID:27857962 PMID:27918309 PMID:28003660 PMID:28007021 PMID:28063098 PMID:28078069 PMID:28166811 PMID:28224104 PMID:28259615 PMID:28269792 PMID:28290972 PMID:28325813 PMID:28326467 PMID:28357410 PMID:28403410 PMID:28424332 PMID:28492532 PMID:28496993 PMID:28527222 PMID:28584051 PMID:28687594 PMID:28750945 PMID:28818389 PMID:29028638 PMID:29096039 PMID:29169929 PMID:29172004 PMID:29178655 PMID:29261186 PMID:29298851 PMID:29344738 PMID:29355282 PMID:29382405 PMID:29417091 PMID:29556213 PMID:29576327 PMID:29608462 PMID:29629541 PMID:29635721 PMID:29667327 PMID:29669168 PMID:29701772 PMID:29792937 PMID:29802573 PMID:30115273 PMID:30122538 PMID:30155320 PMID:30155738 PMID:30236257 PMID:30236258 PMID:30291343 PMID:30325262 PMID:30329129 PMID:30406384 PMID:30499100 PMID:30609409 PMID:30611313 PMID:30652412 PMID:30724636 PMID:30755392 PMID:30788618 PMID:30827497 PMID:30842289 PMID:30864471 PMID:30872186 PMID:30916033 PMID:31016048 PMID:31055738 PMID:31068157 PMID:31107960 PMID:31127727 PMID:31130284 PMID:31135626 PMID:31165076 PMID:31206373 PMID:31301762 PMID:31304636 PMID:31321302 PMID:31395954 PMID:31407473 PMID:31447099 PMID:31517061 PMID:31559918 PMID:31589614 PMID:31618753 PMID:31680123 PMID:31680349 PMID:31742715 PMID:31841587 PMID:31851124 PMID:31903994 PMID:31994743 PMID:32054689 PMID:32098966 PMID:32165824 PMID:32236737 PMID:32304219 PMID:32337335 PMID:32371413 PMID:32403337 PMID:32461654 PMID:32528171 PMID:32600061 PMID:32665702 PMID:32861507 PMID:32899693 PMID:32919876 PMID:32978841 PMID:33037202 PMID:33060286 PMID:33146414 PMID:33176865 PMID:33190635 PMID:33258288 PMID:33259453 PMID:33333461 PMID:33458582 PMID:33490280 PMID:33564012 PMID:33625594 PMID:33646171 PMID:33726816 PMID:33758288 PMID:33767344 PMID:34000440 PMID:34008892 PMID:34106991 PMID:34127251 PMID:34316023 PMID:34411415 PMID:34426522 PMID:34428338 PMID:34440373 PMID:34463354 PMID:34535181 PMID:34595679 PMID:34625927 PMID:34645488 PMID:34809703 PMID:34904211 PMID:35081925 PMID:35178478 PMID:35285867 PMID:35361824 PMID:35387801 PMID:35428369 PMID:35535697 PMID:35548885 PMID:35549722 PMID:35599849 PMID:35627144 PMID:35666680 PMID:35693006 PMID:35697689 PMID:35846108 PMID:35849058 PMID:36100962 PMID:36208971 PMID:36283893 PMID:36474027 PMID:36628841 PMID:37273706 PMID:37510298 PMID:37541188 PMID:37712079 PMID:37937776 PMID:39033378 PMID:214555645 PMID:34257294 PMID:34980804 PMID:30236258 More...
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RGD:329812001, RGD:329812000, RGD:329811997 |
NCBI chr 1:84,292,578...84,423,824
Ensembl chr 1:84,292,578...84,423,812
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G |
Trpv1 |
transient receptor potential cation channel, subfamily V, member 1 |
|
ISO |
ClinVar Annotator: match by term: Malignant hyperthermia of anesthesia |
ClinVar |
PMID:25741868 |
|
NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
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G |
Alpg |
alkaline phosphatase, germ cell |
|
ISO |
ClinVar Annotator: match by term: Lethal multiple pterygium syndrome |
ClinVar |
PMID:28492532 |
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NCBI chr 9:87,748,721...87,761,500
Ensembl chr 9:87,753,648...87,757,836
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G |
Alpi |
alkaline phosphatase, intestinal |
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ISO |
ClinVar Annotator: match by term: Lethal multiple pterygium syndrome |
ClinVar |
PMID:28492532 |
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NCBI chr 9:87,773,411...87,776,877
Ensembl chr 9:87,773,411...87,776,877
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G |
Alpp |
alkaline phosphatase, placental |
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ISO |
ClinVar Annotator: match by term: Lethal multiple pterygium syndrome |
ClinVar |
PMID:28492532 |
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NCBI chr 9:87,765,846...87,768,606
Ensembl chr 9:87,765,860...87,768,606
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G |
Chrna1 |
cholinergic receptor nicotinic alpha 1 subunit |
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ISO |
ClinVar Annotator: match by term: Lethal multiple pterygium syndrome |
OMIM ClinVar |
PMID:6287911 PMID:7619526 PMID:7863154 PMID:9158151 PMID:9221765 PMID:9536098 PMID:10195214 PMID:14719537 PMID:15907919 PMID:16199547 PMID:17576681 PMID:18252226 PMID:18806275 PMID:22406191 PMID:22728938 PMID:23037934 PMID:24121633 PMID:25348405 PMID:25450229 PMID:25741868 PMID:25741885 PMID:26467025 PMID:27748205 PMID:28492532 PMID:29054425 PMID:30177536 PMID:31680349 PMID:33216040 PMID:36634413 More...
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NCBI chr 3:58,454,763...58,469,832
Ensembl chr 3:58,454,744...58,469,840
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G |
Chrnd |
cholinergic receptor nicotinic delta subunit |
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ISO |
ClinVar Annotator: match by term: Lethal multiple pterygium syndrome |
OMIM ClinVar |
PMID:8872460 PMID:9536098 PMID:11435464 PMID:11782989 PMID:16199547 PMID:16916845 PMID:17576681 PMID:18252226 PMID:18398509 PMID:18414213 PMID:23108489 PMID:25264167 PMID:25741868 PMID:26467025 PMID:26578207 PMID:28024842 PMID:28492532 PMID:28518170 PMID:29382405 PMID:29390429 PMID:29399782 PMID:30467950 PMID:31560172 PMID:32070632 PMID:32360402 PMID:32403337 PMID:32528171 PMID:34791078 More...
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NCBI chr 9:87,862,417...87,870,833
Ensembl chr 9:87,862,407...87,870,833
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G |
Chrng |
cholinergic receptor nicotinic gamma subunit |
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ISO |
ClinVar Annotator: match by term: Lethal multiple pterygium syndrome |
OMIM ClinVar |
PMID:16826520 PMID:16826531 PMID:22167768 PMID:24038971 PMID:24254455 PMID:24319099 PMID:25326635 PMID:25411939 PMID:25608830 PMID:25741868 PMID:25957469 PMID:26578207 PMID:26752647 PMID:27245440 PMID:28492532 PMID:29054425 PMID:30868735 PMID:31230720 PMID:31680349 PMID:32536119 PMID:32901917 PMID:33060286 PMID:34008892 PMID:34440395 More...
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NCBI chr 9:87,878,085...87,884,193
Ensembl chr 9:87,878,085...87,914,482
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G |
Dis3l2 |
DIS3-like 3'-5' exoribonuclease 2 |
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ISO |
ClinVar Annotator: match by term: Lethal multiple pterygium syndrome |
ClinVar |
PMID:28492532 |
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NCBI chr 9:87,355,409...87,736,616
Ensembl chr 9:87,356,457...87,736,616
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G |
Ecel1 |
endothelin converting enzyme-like 1 |
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ISO |
ClinVar Annotator: match by term: Lethal multiple pterygium syndrome |
ClinVar |
PMID:28492532 |
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NCBI chr 9:87,819,516...87,829,154
Ensembl chr 9:87,816,718...87,826,675
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G |
Prss56 |
serine protease 56 |
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ISO |
ClinVar Annotator: match by term: Lethal multiple pterygium syndrome |
ClinVar |
PMID:28492532 |
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NCBI chr 9:87,842,806...87,859,978
Ensembl chr 9:87,854,805...87,859,978
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G |
Abcc8 |
ATP binding cassette subfamily C member 8 |
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ISO |
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RGD |
PMID:18316485 |
RGD:2301903 |
NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510
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G |
Acvr2b |
activin A receptor type 2B |
treatment |
ISO |
human construct in mouse model mRNA, protein:decreased expression:heart (mouse) |
RGD |
PMID:30765322 PMID:30765322 |
RGD:329849112, RGD:329849112 |
NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:119,138,812...119,170,458
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G |
Ada |
adenosine deaminase |
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IDA |
protein:increased expression |
RGD |
PMID:16641873 |
RGD:1624305 |
NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
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ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:16155579 |
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NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Adrb1 |
adrenoceptor beta 1 |
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IMP ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:10900253 PMID:17201736 |
RGD:5129149 |
NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259
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G |
Adrb2 |
adrenoceptor beta 2 |
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IDA |
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RGD |
PMID:16269402 |
RGD:1598746 |
NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
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G |
Ager |
advanced glycosylation end product-specific receptor |
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IEP |
protein:increased expression:heart (rat) |
RGD |
PMID:16505177 |
RGD:1625342 |
NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
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G |
Agl |
amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase |
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IMP |
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RGD |
PMID:9281456 |
RGD:1598779 |
NCBI chr 2:204,705,053...204,760,966
Ensembl chr 2:204,705,053...204,760,828
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G |
Agt |
angiotensinogen |
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ISO |
CTD Direct Evidence: marker/mechanism|therapeutic |
CTD |
PMID:2535056 PMID:19166939 |
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NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Agtr1a |
angiotensin II receptor, type 1a |
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IEP |
protein:increased expression:myocardium |
RGD |
PMID:21078800 |
RGD:5129194 |
NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
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G |
Ahr |
aryl hydrocarbon receptor |
treatment |
IMP |
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RGD |
PMID:35788946 |
RGD:401793705 |
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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G |
Aifm1 |
apoptosis inducing factor, mitochondria associated 1 |
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IEP ISO |
protein:decreased expression:mitochondrion: |
RGD |
PMID:23685150 PMID:23685150 |
RGD:10053560, RGD:10053560 |
NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256
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G |
Akt1 |
AKT serine/threonine kinase 1 |
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IDA |
protein:increased phosphorylation:heart left ventricle |
RGD |
PMID:20217242 |
RGD:5509104 |
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Akt2 |
AKT serine/threonine kinase 2 |
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IDA |
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RGD |
PMID:16418318 |
RGD:2313347 |
NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
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G |
Alb |
albumin |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:9572063 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Aldh2 |
aldehyde dehydrogenase 2 family member |
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IDA |
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RGD |
PMID:23468836 |
RGD:7241598 |
NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
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G |
Alox5 |
arachidonate 5-lipoxygenase |
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IMP |
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RGD |
PMID:20011686 |
RGD:2317527 |
NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
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G |
Angpt2 |
angiopoietin 2 |
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IEP |
mRNA, protein:increased expression:myocardium (rat) |
RGD |
PMID:12737621 |
RGD:1601505 |
NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804
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G |
Ank1 |
ankyrin 1 |
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IDA |
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RGD |
PMID:9378703 |
RGD:1599110 |
NCBI chr16:68,876,294...69,054,963
Ensembl chr16:68,877,504...69,054,759
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G |
Ank2 |
ankyrin 2 |
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IDA |
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RGD |
PMID:9378703 |
RGD:1599110 |
NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923
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G |
Ankrd1 |
ankyrin repeat domain 1 |
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IEP |
protein:decreased expression:myocardium |
RGD |
PMID:19299913 |
RGD:5133278 |
NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
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G |
Anxa1 |
annexin A1 |
treatment |
IEP ISO |
protein:increased expression:heart, leukocyte |
RGD |
PMID:11641252 PMID:22924634 PMID:22924634 |
RGD:2306910, RGD:7421655, RGD:7421655 |
NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
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G |
Apex1 |
apurinic/apyrimidinic endodeoxyribonuclease 1 |
|
IEP |
protein:altered localization:cytoplasm |
RGD |
PMID:17602955 |
RGD:2315672 |
NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
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G |
Arrb2 |
arrestin, beta 2 |
|
IEP |
|
RGD |
PMID:29016703 |
RGD:13506827 |
NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
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G |
Atf3 |
activating transcription factor 3 |
|
IEP |
|
RGD |
PMID:11485922 |
RGD:7327201 |
NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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G |
Atp1a1 |
ATPase Na+/K+ transporting subunit alpha 1 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:29702141 |
|
NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
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|
G |
Atp2a1 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 |
|
IMP |
|
RGD |
PMID:17630344 |
RGD:13782075 |
NCBI chr 1:181,026,606...181,044,859
Ensembl chr 1:181,026,608...181,044,838
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|
G |
Atp2a2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
treatment |
ISO IEP |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:10734148 PMID:28637456 |
RGD:13782080 |
NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
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G |
Atp5f1d |
ATP synthase F1 subunit delta |
treatment |
IEP |
protein:decreased expression:myocardium (rat) |
RGD |
PMID:26109848 PMID:25305180 |
RGD:13792666, RGD:13792676 |
NCBI chr 7:9,560,604...9,565,919
Ensembl chr 7:9,560,608...9,565,929
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G |
Bad |
BCL2-associated agonist of cell death |
treatment |
IEP IDA |
protein:increased expression, decreased serine phosphorylation:heart |
RGD |
PMID:15339931 PMID:23364609 |
RGD:2292700, RGD:10053674 |
NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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G |
Bax |
BCL2 associated X, apoptosis regulator |
treatment |
IEP ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:20026869 PMID:21223820 PMID:25547710 PMID:31583047 |
RGD:10054103, RGD:13782178, RGD:155230831 |
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
treatment |
IEP IDA |
|
RGD |
PMID:16289365 PMID:23364609 PMID:20821058 PMID:31583047 |
RGD:1599484, RGD:10053674, RGD:11561911, RGD:155230831 |
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2l1 |
Bcl2-like 1 |
treatment |
IDA |
|
RGD |
PMID:12668130 |
RGD:11035287 |
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 Ensembl chr 1:141,253,523...141,303,479
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G |
Becn1 |
beclin 1 |
treatment |
IDA ISO |
|
RGD |
PMID:20821058 PMID:20812860 |
RGD:11561911, RGD:11561944 |
NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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G |
Bid |
BH3 interacting domain death agonist |
|
IDA IEP |
protein:increased cleavage:heart: |
RGD |
PMID:19940077 PMID:11934844 |
RGD:2317561, RGD:13782263 |
NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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G |
Blk |
BLK proto-oncogene, Src family tyrosine kinase |
|
IEP |
mRNA:increased expression:left ventricle (rat) |
RGD |
PMID:17562528 |
RGD:1642307 |
NCBI chr15:37,626,746...37,665,053
Ensembl chr15:37,627,039...37,665,031
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G |
Bnip3 |
BCL2 interacting protein 3 |
treatment |
IMP IEP |
protein:decreased expression:myocardium (human) |
RGD |
PMID:16645637 PMID:28661226 |
RGD:11561983, RGD:155260328 |
NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
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G |
Brd4 |
bromodomain containing 4 |
|
ISO |
mRNA,protein:increased expression:heart |
RGD |
PMID:33982231 |
RGD:155883171 |
NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539
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G |
Btg2 |
BTG anti-proliferation factor 2 |
|
IEP |
mRNA:increased expression:heart |
RGD |
PMID:12909328 |
RGD:2289075 |
NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
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G |
C3 |
complement C3 |
|
IEP |
protein:increased expression:myocardium |
RGD |
PMID:11560858 |
RGD:1582136 |
NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
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G |
C5 |
complement C5 |
treatment |
IDA IMP |
|
RGD |
PMID:9631876 PMID:23067403 |
RGD:1600666, RGD:7411626 |
NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994
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G |
Casp1 |
caspase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:14998631 |
|
NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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G |
Casp12 |
caspase 12 |
treatment |
IEP ISO |
protein:increased activity:myocardium CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:14998631 PMID:19406177 PMID:25547710 |
RGD:2311458, RGD:13782178 |
NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
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G |
Casp3 |
caspase 3 |
treatment ameliorates |
IMP ISO IEP |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:14998631 PMID:18470603 PMID:29538428 PMID:30259997 |
RGD:2293314, RGD:13782276, RGD:329337366 |
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp7 |
caspase 7 |
treatment |
ISO IEP |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:14998631 PMID:29538428 |
RGD:13782276 |
NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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G |
Casp8 |
caspase 8 |
|
ISO IEP |
CTD Direct Evidence: marker/mechanism protein:increased activity:cardiomyocyte |
CTD RGD |
PMID:14998631 PMID:11934844 |
RGD:13782263 |
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
ameliorates treatment |
ISO IEP |
CTD Direct Evidence: marker/mechanism protein:increased activity:cardiomyocyte,endothelial cell |
CTD RGD |
PMID:14998631 PMID:30259997 PMID:29538428 PMID:11934844 |
RGD:329337366, RGD:13782276, RGD:13782263 |
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Casr |
calcium-sensing receptor |
|
IEP |
protein:increased expression:ventricular myocardium (rat) |
RGD |
PMID:21766206 |
RGD:7205698 |
NCBI chr11:64,235,251...64,304,811
Ensembl chr11:64,235,251...64,304,811
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G |
Cast |
calpastatin |
ameliorates |
IEP ISO |
human transcript overexpression in rat model |
RGD |
PMID:12482022 PMID:14519437 |
RGD:5683872, RGD:405101692 |
NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659
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G |
Cat |
catalase |
|
IEP ISO |
CTD Direct Evidence: therapeutic |
CTD RGD |
PMID:21600015 PMID:11510883 |
RGD:1581149 |
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cbl |
Cbl proto-oncogene |
severity |
ISO |
|
RGD |
PMID:24583314 |
RGD:11251947 |
NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
|
IEP ISO |
mRNA:increased expression:heart (rat) CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:12087064 PMID:10908159 |
RGD:8549625 |
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccr2 |
C-C motif chemokine receptor 2 |
|
ISO |
protein:decreased expression:monocyte: |
RGD |
PMID:15786508 |
RGD:4892017 |
NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
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G |
Ccr5 |
C-C motif chemokine receptor 5 |
treatment |
ISO IEP |
protein:decreased expression:blood, monocyte (human) |
RGD |
PMID:15786508 PMID:23456481 |
RGD:4892017, RGD:8552227 |
NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
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G |
Cflar |
CASP8 and FADD-like apoptosis regulator |
treatment |
IEP |
|
RGD |
PMID:18466417 |
RGD:11341714 |
NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
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G |
Cnr1 |
cannabinoid receptor 1 |
|
IMP |
|
RGD |
PMID:18771032 |
RGD:2316217 |
NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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G |
Cnr2 |
cannabinoid receptor 2 |
|
IMP |
|
RGD |
PMID:17950273 |
RGD:2316224 |
NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
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G |
Cobll1 |
cordon-bleu WH2 repeat protein-like 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34355838 |
|
NCBI chr 3:49,753,260...49,915,168
Ensembl chr 3:49,753,262...49,915,194
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G |
Crebbp |
CREB binding protein |
treatment |
IEP |
|
RGD |
PMID:24338162 |
RGD:153352322 |
NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
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G |
Crp |
C-reactive protein |
|
IEP |
protein:increased expression:serum |
RGD |
PMID:21122204 |
RGD:5128547 |
NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
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G |
Cx3cr1 |
C-X3-C motif chemokine receptor 1 |
|
ISO |
protein:decreased expression:blood, monocyte |
RGD |
PMID:15786508 |
RGD:4892017 |
NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
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G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
|
IMP |
|
RGD |
PMID:11342480 |
RGD:5135269 |
NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
|
IMP |
|
RGD |
PMID:11342480 |
RGD:5135269 |
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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G |
Cxcl6 |
C-X-C motif chemokine ligand 6 |
|
IMP |
|
RGD |
PMID:11342480 |
RGD:5135269 |
NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093
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G |
Cybb |
cytochrome b-245 beta chain |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19207477 |
|
NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586
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G |
Diablo |
diablo, IAP-binding mitochondrial protein |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:14998631 |
|
NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387
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G |
Dnm1l |
dynamin 1-like |
ameliorates |
ISO |
|
RGD |
PMID:30259997 |
RGD:329337366 |
NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
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G |
Ece1 |
endothelin converting enzyme 1 |
|
IMP IEP |
|
RGD |
PMID:18586023 PMID:12193087 |
RGD:4892580, RGD:7244160 |
NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371
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G |
Edn1 |
endothelin 1 |
|
IEP ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:15642760 PMID:16700825 PMID:18586023 |
RGD:4892580 |
NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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G |
Ednra |
endothelin receptor type A |
|
IMP |
|
RGD |
PMID:18586023 |
RGD:4892580 |
NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
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G |
Ednrb |
endothelin receptor type B |
|
IMP |
|
RGD |
PMID:21048781 |
RGD:4892332 |
NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
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G |
Egln1 |
egl-9 family hypoxia-inducible factor 1 |
susceptibility |
ISO |
|
RGD |
PMID:20185832 |
RGD:11251775 |
NCBI chr19:52,867,900...52,907,308
Ensembl chr19:52,869,486...52,907,777
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G |
Ephx2 |
epoxide hydrolase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19834332 |
|
NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
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G |
Esr1 |
estrogen receptor 1 |
|
IMP |
|
RGD |
PMID:18314151 |
RGD:4892299 |
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
|
ISO |
|
RGD |
PMID:18656630 |
RGD:5508820 |
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G |
Fadd |
Fas associated via death domain |
treatment |
ISO IEP |
|
RGD |
PMID:26038570 PMID:26948086 |
RGD:11341801, RGD:13792504 |
NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
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G |
Fas |
Fas cell surface death receptor |
treatment |
IDA |
|
RGD |
PMID:21316771 |
RGD:8686424 |
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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G |
Fis1 |
fission, mitochondrial 1 |
ameliorates |
ISO |
|
RGD |
PMID:30259997 |
RGD:329337366 |
NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377
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G |
Gapdh |
glyceraldehyde-3-phosphate dehydrogenase |
treatment |
IEP |
|
RGD |
PMID:27129213 |
RGD:11574725 |
NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
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G |
Gcg |
glucagon |
treatment |
ISO |
|
RGD |
PMID:24125539 |
RGD:10402369 |
NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929
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G |
Gdf11 |
growth differentiation factor 11 |
|
ISO |
mRNA, protein:decreased expression:heart (mouse) |
RGD |
PMID:30765322 |
RGD:329849112 |
NCBI chr 7:1,311,732...1,325,211
Ensembl chr 7:1,311,732...1,320,725
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G |
Gja1 |
gap junction protein, alpha 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17445419 |
|
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
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G |
Glrx |
glutaredoxin |
|
IEP |
mRNA:decreased expression:heart: |
RGD |
PMID:18163565 |
RGD:2306160 |
NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
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G |
Gpx3 |
glutathione peroxidase 3 |
|
ISO |
|
RGD |
PMID:11043918 |
RGD:401827843 |
NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
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G |
Grk2 |
G protein-coupled receptor kinase 2 |
treatment susceptibility severity |
IMP ISO IDA |
associated with Diabetes Mellitus, Experimental associated with Hypertension protein:increased expression:heart, mitochondrion (mouse) |
RGD |
PMID:27865836 PMID:27601479 PMID:27296507 PMID:24170934 PMID:23467820 |
RGD:13513990, RGD:13513993, RGD:13513995, RGD:13792704, RGD:13792779 |
NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
treatment |
IDA IEP |
|
RGD |
PMID:20217242 PMID:26918336 PMID:29978610 |
RGD:5509104, RGD:13792772, RGD:13792725 |
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Gsr |
glutathione-disulfide reductase |
treatment |
IEP |
|
RGD |
PMID:24769323 |
RGD:10401892 |
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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G |
H19 |
H19 imprinted maternally expressed transcript |
ameliorates |
ISO |
|
RGD |
PMID:31284127 |
RGD:158013771 |
NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134
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G |
H2ax |
H2A.X variant histone |
treatment |
IDA |
|
RGD |
PMID:23108649 |
RGD:8693739 |
NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 Ensembl chr 4:44,671,786...44,673,239
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G |
Hdac3 |
histone deacetylase 3 |
ameliorates |
ISO |
|
RGD |
PMID:33982231 |
RGD:155883171 |
NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
treatment |
IEP ISO IDA |
mRNA:increased expression:heart CTD Direct Evidence: marker/mechanism protein:increased expression:myocardium |
CTD RGD |
PMID:18549825 PMID:22050707 PMID:12189448 PMID:20170615 PMID:19727523 |
RGD:1626327, RGD:9068872, RGD:5147885 |
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hmgb1 |
high mobility group box 1 |
treatment |
IEP ISO IDA |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:21113057 PMID:23531454 PMID:19540007 |
RGD:10402066, RGD:10402170 |
NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565 Ensembl chr16:5,901,586...5,978,565
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G |
Hmox1 |
heme oxygenase 1 |
treatment |
IDA ISO IEP |
|
RGD |
PMID:12709584 PMID:23921302 PMID:22179023 |
RGD:1598392, RGD:10755585, RGD:10755573 |
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hrh2 |
histamine receptor H 2 |
susceptibility |
ISO |
|
RGD |
PMID:23467745 |
RGD:9685524 |
NCBI chr17:10,366,004...10,407,791
Ensembl chr17:10,368,298...10,407,631
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G |
Hrh3 |
histamine receptor H3 |
|
IDA |
|
RGD |
PMID:15076218 |
RGD:1626433 |
NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642
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G |
Hsf1 |
heat shock transcription factor 1 |
|
ISO |
|
RGD |
PMID:22426029 |
RGD:10402789 |
NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
|
|
G |
Hspa1a |
heat shock protein family A (Hsp70) member 1A |
treatment |
IEP |
|
RGD |
PMID:20501665 |
RGD:10003160 |
NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
|
|
G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
treatment |
IEP |
|
RGD |
PMID:24129401 PMID:25547710 |
RGD:11354962, RGD:13782178 |
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
|
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G |
Htra2 |
HtrA serine peptidase 2 |
|
ISO |
protein:increased expression:myocardium, cytosol (mouse) |
RGD |
PMID:15611365 |
RGD:5688376 |
NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095
|
|
G |
Icam1 |
intercellular adhesion molecule 1 |
|
IEP ISO |
protein:increased expression:heart (rat) CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:12087064 PMID:20851484 |
RGD:4145348 |
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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|
G |
Il10 |
interleukin 10 |
treatment |
IEP IDA |
protein:increased expression:plasma |
RGD |
PMID:19275881 PMID:23840272 |
RGD:2311056, RGD:7365001 |
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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Il17a |
interleukin 17A |
treatment |
IMP |
|
RGD |
PMID:22030025 |
RGD:9068944 |
NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
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G |
Il18 |
interleukin 18 |
|
ISO IDA |
|
RGD |
PMID:19164288 PMID:19805173 |
RGD:4889578, RGD:4889400 |
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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G |
Il18bp |
interleukin 18 binding protein |
|
ISO |
mRNA:increased expression:heart |
RGD |
PMID:19164288 PMID:19805173 |
RGD:4889578, RGD:4889400 |
NCBI chr 1:156,372,923...156,374,963
Ensembl chr 1:156,372,883...156,374,963
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G |
Il18rap |
interleukin 18 receptor accessory protein |
|
ISO |
|
RGD |
PMID:19164288 |
RGD:4889578 |
NCBI chr 9:42,768,112...42,800,964
Ensembl chr 9:42,768,220...42,800,959
|
|
G |
Il1a |
interleukin 1 alpha |
treatment |
ISO IEP |
|
RGD |
PMID:8576926 PMID:7622355 |
RGD:7794741, RGD:7794764 |
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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|
G |
Il1b |
interleukin 1 beta |
treatment |
IEP |
mRNA:increased expression:heart |
RGD |
PMID:17134725 PMID:31583047 |
RGD:1626628, RGD:155230831 |
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
|
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G |
Il1rl2 |
interleukin 1 receptor-like 2 |
|
IMP |
compared to Wild Type in cardiopulmonary bypass model |
RGD |
PMID:32048631 |
RGD:126925167 |
NCBI chr 9:42,591,658...42,639,351
Ensembl chr 9:42,591,934...42,636,667
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G |
Il1rl2tm1(Myh6-cre)Mhzh |
interleukin 1 receptor-like 2; tm1 (Myh6-cre), Mhzh |
|
IMP |
compared to Wild Type in cardiopulmonary bypass model |
RGD |
PMID:32048631 |
RGD:126925167 |
|
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G |
Il1rn |
interleukin 1 receptor antagonist |
|
ISO |
rat model treated with human protein |
RGD |
PMID:22649318 |
RGD:7174360 |
NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
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G |
Il36rn |
interleukin 36 receptor antagonist |
|
IMP |
|
RGD |
PMID:32048631 |
RGD:126925167 |
NCBI chr 3:7,044,419...7,051,016
Ensembl chr 3:7,044,406...7,051,016
|
|
G |
Il36rntm1(Myh6-cre)Mhzh |
interleukin 36 receptor antagonist; tm1, Mhzh |
|
IMP |
|
RGD |
PMID:32048631 |
RGD:126925167 |
|
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G |
Il6 |
interleukin 6 |
treatment |
IDA IEP |
|
RGD |
PMID:27087891 PMID:31583047 |
RGD:11062149, RGD:155230831 |
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Il6r |
interleukin 6 receptor |
|
ISO |
|
RGD |
PMID:16056242 |
RGD:1625435 |
NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
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G |
Inhba |
inhibin subunit beta A |
|
ISO |
mRNA, protein:increased expression:heart (mouse) |
RGD |
PMID:30765322 |
RGD:329849112 |
NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
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G |
Irak1 |
interleukin-1 receptor-associated kinase 1 |
|
IEP |
protein:increased activity:ventricle myocardium (rat) |
RGD |
PMID:15793310 |
RGD:1579809 |
NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521
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G |
Irf9 |
interferon regulatory factor 9 |
exacerbates ameliorates |
ISO |
protein:increased expression:left ventricular free wall |
RGD |
PMID:25150882 PMID:25150882 PMID:25150882 |
RGD:125093742, RGD:125093742, RGD:125093742 |
NCBI chr15:29,095,474...29,101,924
Ensembl chr15:29,095,789...29,101,236
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G |
Jak2 |
Janus kinase 2 |
treatment |
IMP |
associated with Diabetes Mellitus, Experimental |
RGD |
PMID:23796350 PMID:23747931 |
RGD:8694332, RGD:10403071 |
NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
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G |
Kcnj11 |
potassium inwardly-rectifying channel, subfamily J, member 11 |
|
ISO |
|
RGD |
PMID:17906066 |
RGD:7297046 |
NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
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G |
Kcnj8 |
potassium inwardly-rectifying channel, subfamily J, member 8 |
|
IDA |
|
RGD |
PMID:12234964 |
RGD:729109 |
NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603
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|
G |
Klrk1 |
killer cell lectin like receptor K1 |
treatment |
IMP |
|
RGD |
PMID:23953572 |
RGD:9685183 |
NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459
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G |
Kng1 |
kininogen 1 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:2535056 PMID:7856280 |
|
NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555
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G |
Lep |
leptin |
|
IEP |
|
RGD |
PMID:21122204 |
RGD:5128547 |
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Lepr |
leptin receptor |
|
IEP |
mRNA:decreased expression:heart mRNA:altered expression:heart |
RGD |
PMID:15284063 PMID:17134725 |
RGD:5129123, RGD:1626628 |
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
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G |
Lum |
lumican |
|
IDA |
|
RGD |
PMID:11348051 |
RGD:1582122 |
NCBI chr 7:32,358,990...32,365,794
Ensembl chr 7:32,358,614...32,365,793
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|
G |
Map1lc3a |
microtubule-associated protein 1 light chain 3 alpha |
treatment |
IEP ISO |
protein:increased expression:heart |
RGD |
PMID:20821058 PMID:20812860 |
RGD:11561911, RGD:11561944 |
NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670
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G |
Map2k6 |
mitogen-activated protein kinase kinase 6 |
|
ISO |
|
RGD |
PMID:14749328 PMID:15492008 |
RGD:7495840, RGD:1582277 |
NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
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G |
Map3k5 |
mitogen-activated protein kinase kinase kinase 5 |
treatment |
IEP |
|
RGD |
PMID:31583047 |
RGD:155230831 |
NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
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G |
Mapk1 |
mitogen activated protein kinase 1 |
treatment |
IDA |
|
RGD |
PMID:15653762 PMID:25345742 |
RGD:1582282, RGD:13800900 |
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk14 |
mitogen activated protein kinase 14 |
|
ISO |
|
RGD |
PMID:14749328 |
RGD:7495840 |
NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
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|
G |
Mapk3 |
mitogen activated protein kinase 3 |
treatment |
IEP IDA |
|
RGD |
PMID:29741915 PMID:25345742 PMID:28814571 |
RGD:13800564, RGD:13800900, RGD:13800874 |
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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|
G |
Mapk8 |
mitogen-activated protein kinase 8 |
treatment |
IDA IEP |
|
RGD |
PMID:15309413 PMID:31583047 PMID:12883833 |
RGD:1582311, RGD:155230831, RGD:1582312 |
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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G |
Mb |
myoglobin |
|
ISO IDA |
|
RGD |
PMID:15132981 PMID:11972171 |
RGD:1582385, RGD:1582431 |
NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383
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G |
Mbl1 |
mannose binding lectin 1 |
|
IDA IMP ISO |
|
RGD |
PMID:11560858 PMID:20216929 PMID:15972690 |
RGD:1582136, RGD:4889154, RGD:1582131 |
NCBI chr16:17,029,146...17,035,187
Ensembl chr16:17,029,118...17,035,174
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G |
Mbl2 |
mannose binding lectin 2 |
treatment |
ISO |
|
RGD |
PMID:25482922 |
RGD:11530049 |
NCBI chr 1:228,016,439...228,024,736
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G |
Mdm2 |
MDM2 proto-oncogene |
|
IEP |
protein:increased serine phosphorylation:heart ventricle (rat) |
RGD |
PMID:14644432 |
RGD:2317401 |
NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
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G |
Mfn2 |
mitofusin 2 |
treatment |
IEP |
|
RGD |
PMID:24721408 |
RGD:13204835 |
NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
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G |
Mir1 |
microRNA 1 |
treatment |
IMP |
|
RGD |
PMID:29741915 |
RGD:13800564 |
NCBI chr18:1,887,537...1,887,623
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G |
Mir10a |
microRNA 10a |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
|
NCBI chr10:81,283,171...81,283,280
Ensembl chr10:81,283,171...81,283,280
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G |
Mir10b |
microRNA 10b |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
|
NCBI chr 3:59,628,438...59,628,546
Ensembl chr 3:59,628,438...59,628,546
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G |
Mir126a |
microRNA 126a |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
|
NCBI chr 3:9,415,063...9,415,180
Ensembl chr 3:9,415,063...9,415,180
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G |
Mir134 |
microRNA 134 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
|
NCBI chr 6:128,748,908...128,748,980
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G |
Mir137 |
microRNA 137 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
|
NCBI chr 2:206,480,881...206,480,982
Ensembl chr 2:206,480,884...206,480,985
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G |
Mir140 |
microRNA 140 |
exacerbates |
ISO |
miRNA:increased expression:heart, endothelial cells (mouse) |
RGD |
PMID:30259997 PMID:31792649 |
RGD:329337366, RGD:329337374 |
NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675
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G |
Mir142 |
microRNA 142 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
|
NCBI chr10:72,557,864...72,557,950
Ensembl chr10:72,557,857...72,557,967
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G |
Mir145 |
microRNA 145 |
treatment |
IEP |
RNA:decreased expression:heart |
RGD |
PMID:31583047 PMID:33658472 |
RGD:155230831, RGD:329955358 |
NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727
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G |
Mir146b |
microRNA 146b |
|
IEP |
miRNA:increased expression:heart (rat) |
RGD |
PMID:19380620 |
RGD:155882541 |
NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:245,203,438...245,203,525
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G |
Mir181c |
microRNA 181c |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
|
NCBI chr19:23,983,523...23,983,628
Ensembl chr19:23,983,523...23,983,628
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G |
Mir183 |
microRNA 183 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
|
NCBI chr 4:58,788,614...58,788,723
Ensembl chr 4:58,788,614...58,788,723
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G |
Mir186 |
microRNA 186 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
|
NCBI chr 2:246,582,806...246,582,891
Ensembl chr 2:246,582,806...246,582,891
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G |
Mir188 |
microRNA 188 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
|
NCBI chr X:15,247,715...15,247,794
Ensembl chr X:15,247,715...15,247,794
|
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G |
Mir193a |
microRNA 193a |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
|
NCBI chr10:64,672,343...64,672,454
Ensembl chr10:64,672,343...64,672,454
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G |
Mir196b |
microRNA 196b |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
|
NCBI chr 4:81,330,487...81,330,571
Ensembl chr 4:81,330,487...81,330,571
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G |
Mir206 |
microRNA 206 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
|
NCBI chr 9:23,094,249...23,094,332
Ensembl chr 9:23,094,249...23,094,332
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G |
Mir20b |
microRNA 20b |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
|
NCBI chr X:132,422,211...132,422,282
Ensembl chr X:132,422,211...132,422,282
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G |
Mir21 |
microRNA 21 |
exacerbates |
ISO IEP |
CTD Direct Evidence: marker/mechanism miRNA:increased expression:heart (rat) |
CTD RGD |
PMID:22050707 PMID:19380620 PMID:24825878 |
RGD:155882541, RGD:41404665 |
NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
|
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G |
Mir210 |
microRNA 210 |
sexual_dimorphism |
IEP ISO |
miRNA:increased expression:myocardium (human) |
RGD |
PMID:28661226 PMID:35296158 |
RGD:155260328, RGD:155663666 |
NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454
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Mir222 |
microRNA 222 |
ameliorates |
ISO |
|
RGD |
PMID:25863248 |
RGD:152025190 |
NCBI chr X:3,428,904...3,429,006
Ensembl chr X:3,428,904...3,429,006
|
|
G |
Mir23b |
microRNA 23b |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
|
NCBI chr17:1,813,667...1,813,763
Ensembl chr17:1,813,667...1,813,763
|
|
G |
Mir26a |
microRNA 26a |
treatment |
IEP |
|
RGD |
PMID:29978610 |
RGD:13792725 |
NCBI chr 8:118,755,289...118,755,378
Ensembl chr 8:118,755,289...118,755,378
|
|
G |
Mir27a |
microRNA 27a |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
|
NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917
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G |
Mir27b |
microRNA 27b |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
|
NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529
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|
G |
Mir28 |
microRNA 28 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
|
NCBI chr11:75,975,523...75,975,608
Ensembl chr11:75,975,523...75,975,608
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G |
Mir296 |
microRNA 296 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
|
NCBI chr 3:163,051,838...163,051,915
Ensembl chr 3:163,051,838...163,051,915
|
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G |
Mir301b |
microRNA 301b |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
|
NCBI chr11:83,879,816...83,879,893
Ensembl chr11:83,879,816...83,879,893
|
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G |
Mir30a |
microRNA 30a |
treatment |
IEP |
|
RGD |
PMID:25137026 |
RGD:35673319 |
NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670
|
|
G |
Mir30c1 |
microRNA 30c-1 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:34217758 |
|
NCBI chr 5:134,349,237...134,349,325
Ensembl chr 5:134,349,237...134,349,325
|
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G |
Mir320a |
microRNA 320a |
treatment ameliorates |
IMP ISO |
|
RGD |
PMID:27175593 PMID:25268616 PMID:30840298 PMID:19380620 |
RGD:155882540, RGD:155882578, RGD:155882546, RGD:155882541 |
NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473
|
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G |
Mir330 |
microRNA 330 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
|
NCBI chr 1:78,833,178...78,833,274
Ensembl chr 1:78,833,178...78,833,274
|
|
G |
Mir331 |
microRNA 331 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
|
NCBI chr 7:28,527,390...28,527,485
Ensembl chr 7:28,527,390...28,527,485
|
|
G |
Mir337 |
microRNA 337 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
|
NCBI chr 6:128,538,903...128,538,999
Ensembl chr 6:128,538,902...128,538,998
|
|
G |
Mir346 |
microRNA 346 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
|
NCBI chr16:10,218,118...10,218,215
Ensembl chr16:10,218,118...10,218,215
|
|
G |
Mir34c |
microRNA 34c |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
|
NCBI chr 8:51,409,726...51,409,802
Ensembl chr 8:51,409,726...51,409,802
|
|
G |
Mir361 |
microRNA 361 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
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NCBI chr X:78,246,206...78,246,275
Ensembl chr X:78,246,206...78,246,275
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G |
Mir375 |
microRNA 375 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
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NCBI chr 9:76,457,911...76,457,985
Ensembl chr 9:76,457,911...76,457,985
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G |
Mir411 |
microRNA 411 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
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NCBI chr 6:128,723,189...128,723,264
Ensembl chr 6:128,723,184...128,723,279
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G |
Mir429 |
microRNA 429 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
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NCBI chr 5:166,647,459...166,647,543
Ensembl chr 5:166,647,459...166,647,543
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G |
Mir433 |
microRNA 433 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
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NCBI chr 6:128,545,119...128,545,211
Ensembl chr 6:128,545,112...128,545,217
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G |
Mir451a |
microRNA 451a |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
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NCBI chr10:62,961,520...62,961,591
Ensembl chr10:62,961,520...62,961,591
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G |
Mir494 |
microRNA 494 |
ameliorates |
ISO |
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RGD |
PMID:33982231 PMID:20837890 PMID:20837890 |
RGD:155883171, RGD:155883174, RGD:155883174 |
NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793
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G |
Mir500 |
microRNA 500 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
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NCBI chr X:15,258,778...15,258,857
Ensembl chr X:15,258,768...15,258,859
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G |
Mir503 |
microRNA 503 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
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NCBI chr X:132,806,303...132,806,373
Ensembl chr X:132,806,303...132,806,373
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G |
Mir532 |
microRNA 532 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
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NCBI chr X:15,247,315...15,247,393
Ensembl chr X:15,247,315...15,247,393
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G |
Mir542 |
microRNA 542 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
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NCBI chr X:132,802,623...132,802,701
Ensembl chr X:132,802,623...132,802,701
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G |
Mir582 |
microRNA 582 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
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NCBI chr 2:40,928,571...40,928,651
Ensembl chr 2:40,928,571...40,928,651
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Mir598 |
microRNA 598 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
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NCBI chr15:37,962,692...37,962,770
Ensembl chr15:37,962,692...37,962,771
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G |
Mir743a |
microRNA 743a |
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EXP |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
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NCBI chr X:145,402,692...145,402,767
Ensembl chr X:145,402,692...145,402,767
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G |
Mirlet7i |
microRNA let-7i |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22050707 |
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NCBI chr 7:58,642,485...58,642,569
Ensembl chr 7:58,642,480...58,642,571
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G |
Mki67 |
marker of proliferation Ki-67 |
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IDA |
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RGD |
PMID:22405128 |
RGD:6483543 |
NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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Mmp1 |
matrix metallopeptidase 1 |
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ISO IEP |
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RGD |
PMID:12892382 PMID:17996137 |
RGD:1582539, RGD:7207397 |
NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
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Mmp2 |
matrix metallopeptidase 2 |
treatment |
ISO IEP |
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RGD |
PMID:16699069 PMID:23889688 |
RGD:1582614, RGD:8657084 |
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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Mstn |
myostatin |
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ISO |
mRNA, protein:increased expression:heart (mouse) |
RGD |
PMID:30765322 |
RGD:329849112 |
NCBI chr 9:48,452,533...48,458,933
Ensembl chr 9:48,452,533...48,458,933
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Myd88 |
MYD88, innate immune signal transduction adaptor |
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IDA |
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RGD |
PMID:14962484 |
RGD:1302746 |
NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
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Ncl |
nucleolin |
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IEP |
protein:decreased expression:heart |
RGD |
PMID:23594402 |
RGD:9686384 |
NCBI chr 9:86,999,588...87,008,112
Ensembl chr 9:86,998,019...87,008,136
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Ndufs1 |
NADH:ubiquinone oxidoreductase core subunit S1 |
treatment |
IDA |
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RGD |
PMID:21700931 |
RGD:13801200 |
NCBI chr 9:64,546,430...64,579,751
Ensembl chr 9:64,546,225...64,579,893
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G |
Nfe2l1 |
NFE2 like bZIP transcription factor 1 |
treatment |
IEP |
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RGD |
PMID:20501665 |
RGD:10003160 |
NCBI chr10:81,796,055...81,812,926
Ensembl chr10:81,800,366...81,832,318
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Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
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ISO |
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RGD |
PMID:24915518 |
RGD:10412738 |
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Nfkbia |
NFKB inhibitor alpha |
treatment |
IDA |
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RGD |
PMID:19304943 |
RGD:10413871 |
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nos2 |
nitric oxide synthase 2 |
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IEP ISO |
mRNA:decreased expression:heart (rat) CTD Direct Evidence: marker/mechanism|therapeutic |
CTD RGD |
PMID:12003803 PMID:12087064 PMID:14990356 PMID:19207477 PMID:20828608 PMID:21844074 More...
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RGD:5509098 |
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Nos3 |
nitric oxide synthase 3 |
treatment |
IEP IDA ISO IMP |
CTD Direct Evidence: therapeutic |
CTD RGD |
PMID:12354446 PMID:20828747 PMID:29274587 PMID:29299201 PMID:18390819 |
RGD:4891991, RGD:13504684, RGD:13503347, RGD:2292091 |
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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Nox1 |
NADPH oxidase 1 |
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IEP |
mRNA:increased expression:heart |
RGD |
PMID:33658472 |
RGD:329955358 |
NCBI chr X:97,279,058...97,332,291
Ensembl chr X:97,279,056...97,302,236
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Nppb |
natriuretic peptide B |
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IDA |
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RGD |
PMID:21168723 |
RGD:5685663 |
NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
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Nppc |
natriuretic peptide C |
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IDA |
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RGD |
PMID:15337698 |
RGD:1580149 |
NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251
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Npr3 |
natriuretic peptide receptor 3 |
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IDA |
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RGD |
PMID:15337698 |
RGD:1580149 |
NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955
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G |
Npy1r |
neuropeptide Y receptor Y1 |
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IEP |
mRNA:decreased expression:heart left ventricle |
RGD |
PMID:17562528 |
RGD:1642307 |
NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759
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G |
Olr1 |
oxidized low density lipoprotein receptor 1 |
treatment |
IMP |
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RGD |
PMID:12384456 |
RGD:628368 |
NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
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Oprd1 |
opioid receptor, delta 1 |
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IDA |
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RGD |
PMID:12136724 |
RGD:2316590 |
NCBI chr 5:144,306,188...144,340,960
Ensembl chr 5:144,306,188...144,340,960
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