Fibrosis - Ontology Report - Rat Genome Database

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RGD DISEASE ONTOLOGY - ANNOTATIONS

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RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:	Fibrosis	go back to main search page
Accession:	DOID:9000784	browse the term
Definition:	Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.
Synonyms:	exact_synonym:	fibroses
	primary_id:	MESH:D005355
	xref:	EFO:0006890

show annotations for term's descendants Sort by:
Rat (1583) Mouse (1540) Human (8554) Chinchilla (1328) Bonobo (1430) Dog (1463) Squirrel (1348) Pig (1454) Green Monkey (1406) Naked Mole-rat (1343) All
Genes (1521) QTL (19) Strains (43)

Fibrosis

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

actin alpha 2, smooth muscle

CTD Direct Evidence: marker/mechanism

NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554

G

ADAM metallopeptidase domain 10

CTD Direct Evidence: marker/mechanism

NCBI chr 8:71,346,008...71,477,889
Ensembl chr 8:71,345,837...71,477,889

G

adenylate cyclase 5

CTD Direct Evidence: therapeutic

NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974

G

adrenoceptor alpha 2A

CTD Direct Evidence: therapeutic

NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365

G

adrenoceptor alpha 2C

CTD Direct Evidence: marker/mechanism

NCBI chr14:75,470,884...75,472,846
Ensembl chr14:75,471,143...75,472,846

G

adrenoceptor beta 2

CTD Direct Evidence: marker/mechanism

NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512

G

advanced glycosylation end product-specific receptor

associated with Diabetes Mellitus, Experimental

RGD

NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078

G

angiotensinogen

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:12414515 PMID:18785976 PMID:19373235 PMID:25398788 PMID:25807386 More...

NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977

G

angiotensin II receptor, type 1a

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:9596920 PMID:21367774

NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946

G

angiotensin II receptor, type 2

associated with Ureteral Obstruction
associated with Hypertension

RGD

PMID:18327089 PMID:22184331

RGD:6903848, RGD:6903874

NCBI chr X:112,119,876...112,124,060
Ensembl chr X:112,120,228...112,124,057

G

AKT serine/threonine kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

albumin

CTD Direct Evidence: marker/mechanism

NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836

G

angiopoietin 1

CTD Direct Evidence: marker/mechanism

PMID:18480750 PMID:18626492

NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067

G

apelin

CTD Direct Evidence: marker/mechanism

NCBI chr X:127,180,801...127,213,567
Ensembl chr X:127,203,823...127,213,391

G

apolipoprotein E

CTD Direct Evidence: marker/mechanism

NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932

G

ATM serine/threonine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437

G

ATPase H+ transporting accessory protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr X:10,183,983...10,210,948
Ensembl chr X:10,183,068...10,210,918

G

bradykinin receptor B1

RGD

NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747

G

bone morphogenetic protein 10

CTD Direct Evidence: therapeutic

NCBI chr 4:119,872,066...119,877,694
Ensembl chr 4:119,872,045...119,878,627

G

calreticulin

disease_progression

associated with kidney disease; mRNA, protein:increased expression:kidney cortex

RGD

NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414

G

carbonic anhydrase 9

associated with Breast Neoplasms;mRNA:increased expression:breast

RGD

NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838

G

C-C motif chemokine ligand 11

RGD

NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926

G

cellular communication network factor 2

RGD

NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734

G

cyclin D2

CTD Direct Evidence: therapeutic

NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495

G

CD40 ligand

treatment

RGD

NCBI chr X:135,127,052...135,138,768
Ensembl chr X:135,126,969...135,138,306

G

cadherin 1

CTD Direct Evidence: marker/mechanism

NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775

G

cyclin-dependent kinase inhibitor 1B

protein:decreased expression:renal tubule

RGD

NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982

G

CCAAT/enhancer binding protein beta

CTD Direct Evidence: therapeutic

NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473

G

cholinergic receptor nicotinic alpha 1 subunit

CTD Direct Evidence: marker/mechanism

NCBI chr 3:58,454,763...58,469,832
Ensembl chr 3:58,454,744...58,469,840

G

collagen type XVIII alpha 1 chain

mRNA:increased expression:liver

RGD

NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593

G

collagen type I alpha 1 chain

CTD Direct Evidence: marker/mechanism

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

G

collagen type I alpha 2 chain

CTD Direct Evidence: marker/mechanism

NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867

G

collagen type III alpha 1 chain

CTD Direct Evidence: marker/mechanism

NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547

G

colony stimulating factor 3

CTD Direct Evidence: therapeutic

PMID:18785976 PMID:20005281

NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603

G

catenin beta 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111

G

cytochrome P450, family 11, subfamily b, polypeptide 2

protein:increased expression:liver (rat)

RGD

NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004

G

cytochrome P450, family 19, subfamily a, polypeptide 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758

G

decorin

mRNA:increased expression:kidney
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:16005714 PMID:16005714

NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270

G

ferrochelatase

CTD Direct Evidence: marker/mechanism

NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348

G

GATA binding protein 1

RGD

NCBI chr X:14,529,706...14,537,530
Ensembl chr X:14,529,702...14,537,530

G

glutathione peroxidase 4

CTD Direct Evidence: marker/mechanism

NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982

G

histone deacetylase 3

protein:increased expression:penis:

RGD

NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856

G

histone deacetylase 4

protein:increased expression:penis:

RGD

NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164

G

heme oxygenase 1

CTD Direct Evidence: therapeutic

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

intercellular adhesion molecule 1

mRNA, protein:increased expression:pancreas

RGD

NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438

G

interleukin 13

treatment

associated with Venous Thrombosis

RGD

NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737

G

interleukin 1 beta

CTD Direct Evidence: therapeutic

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 1 receptor antagonist

CTD Direct Evidence: therapeutic

NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445

G

interleukin 4

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:24286936 PMID:10486156

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

G

KLF transcription factor 5

severity

RGD

NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445

G

kallikrein 1

CTD Direct Evidence: therapeutic

NCBI chr 1:94,642,644...94,646,760
Ensembl chr 1:94,642,687...94,646,754

G

leptin receptor

CTD Direct Evidence: marker/mechanism

PMID:20567778 PMID:29988851 PMID:36066211

NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908

G

galectin 3

CTD Direct Evidence: marker/mechanism

NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025

G

lipase A, lysosomal acid type

CTD Direct Evidence: marker/mechanism

NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633

G

lumican

mRNA:increased expression:liver
associated with Pancreatitis;mRNA, protein:increased expression, altered localization:pancreas

RGD

PMID:1385211 PMID:12645630

RGD:2317695, RGD:724427

NCBI chr 7:32,358,990...32,365,794
Ensembl chr 7:32,358,614...32,365,793

G

mitogen activated protein kinase kinase 7

CTD Direct Evidence: marker/mechanism

NCBI chr12:2,591,312...2,600,534
Ensembl chr12:2,591,219...2,604,222

G

microRNA 133a-1

CTD Direct Evidence: therapeutic

NCBI chr18:1,885,082...1,885,168

G

microRNA 155

RGD

NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718

G

microRNA 21

CTD Direct Evidence: marker/mechanism

NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348

G

microRNA 217

CTD Direct Evidence: marker/mechanism

NCBI chr14:102,531,505...102,531,609
Ensembl chr14:102,531,505...102,531,609

G

microRNA 30d

CTD Direct Evidence: marker/mechanism

NCBI chr 7:100,136,391...100,136,472
Ensembl chr 7:100,136,391...100,136,472

G

microRNA 30e

CTD Direct Evidence: marker/mechanism

NCBI chr 5:134,352,232...134,352,323
Ensembl chr 5:134,352,232...134,352,323

G

microRNA let-7f-2

CTD Direct Evidence: marker/mechanism

NCBI chr X:20,980,632...20,980,714
Ensembl chr X:20,980,632...20,980,714

G

matrix metallopeptidase 2

protein:increased expression:liver

RGD

NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870

G

matrix metallopeptidase 9

protein:increased expression:liver

RGD

NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120

G

notch receptor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088

G

natriuretic peptide receptor 1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:175,934,181...175,950,118
Ensembl chr 2:175,934,181...175,949,505

G

poly (ADP-ribose) polymerase 1

associated with Ureteral Obstruction

RGD

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

G

platelet derived growth factor subunit B

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:22004089 PMID:17195235 PMID:11780721 PMID:8644858

RGD:6482660, RGD:6482691, RGD:6482673

NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984

G

platelet derived growth factor D

CTD Direct Evidence: marker/mechanism

NCBI chr 8:3,488,448...3,722,395
Ensembl chr 8:3,488,423...3,722,395

G

prohibitin 1

associated with Glomerulonephritis;protein:decreased expression:kidney, epithelial cell

RGD

NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042

G

phosphorylase kinase catalytic subunit gamma 2

associated with Glycogen Storage Disease Type Ix;DNA:mutations:multiple (human)

RGD

NCBI chr 1:182,184,362...182,197,124
Ensembl chr 1:182,184,650...182,197,124

G

paired-like homeobox 2a

RGD

NCBI chr 1:156,178,754...156,183,118
Ensembl chr 1:156,178,754...156,183,118

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:12963636 PMID:21866628

NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043

G

peroxisome proliferator-activated receptor gamma

associated with Hypertension

RGD

PMID:18360056 PMID:18511847

RGD:2301893, RGD:2301856

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

G

prostaglandin-endoperoxide synthase 2

associated with Cholestasis
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:11872629 PMID:18462380

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

renin

CTD Direct Evidence: marker/mechanism

NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489

G

ras homolog family member A

associated with Hypertension;protein:increased activation:heart

RGD

NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746

G

sphingosine-1-phosphate receptor 2

CTD Direct Evidence: therapeutic

NCBI chr 8:19,503,276...19,514,169
Ensembl chr 8:19,502,627...19,523,574

G

secreted frizzled-related protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286

G

sirtuin 1

CTD Direct Evidence: marker/mechanism

NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260

G

sirtuin 6

CTD Direct Evidence: marker/mechanism

NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914

G

solute carrier family 27 member 2

CTD Direct Evidence: marker/mechanism

NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208

G

suppressor of cytokine signaling 3

RGD

NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787

G

superoxide dismutase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

G

superoxide dismutase 3

RGD

NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990

G

sphingosine kinase 1

CTD Direct Evidence: therapeutic

NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240

G

secreted phosphoprotein 1

RGD

NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162

G

signal transducer and activator of transcription 3

CTD Direct Evidence: marker/mechanism

NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057

G

signal transducer and activator of transcription 6

RGD

NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495

G

tachykinin, precursor 1

CTD Direct Evidence: marker/mechanism

NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178

G

transforming growth factor, beta 1

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:10469268 PMID:16306446 PMID:17947678 PMID:18705752 PMID:24142982 More...

RGD:737732, RGD:11073665, RGD:7394820

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

G

thrombospondin 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440

G

tRNA-histidine guanylyltransferase 1-like

CTD Direct Evidence: marker/mechanism

NCBI chr10:30,387,929...30,396,579
Ensembl chr10:30,387,940...30,396,687

G

toll-like receptor 4

CTD Direct Evidence: marker/mechanism

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

G

tumor necrosis factor

CTD Direct Evidence: marker/mechanism

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

tryptophan hydroxylase 1

RGD

NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344

G

vimentin

CTD Direct Evidence: marker/mechanism

NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187

alcoholic liver cirrhosis

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aldehyde dehydrogenase 2 family member

susceptibility

DNA:missense mutation:cds:p.E504K (human)
DNA:missense mutation:cds: (rs671) (human)
associated with alcohol dependence;DNA:missense mutation:exon 12:p.E487K (human)

RGD

PMID:29779728 PMID:23550892 PMID:11051375

RGD:14696777, RGD:15042864, RGD:15042858

NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521

G

BCL2, apoptosis regulator

CTD Direct Evidence: marker/mechanism

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

catalase

CTD Direct Evidence: marker/mechanism

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

2',3'-cyclic nucleotide 3' phosphodiesterase

protein:decreased expression:brain

RGD

NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720

G

collagen type III alpha 1 chain

CTD Direct Evidence: marker/mechanism

NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547

G

C-reactive protein

severity

RGD

NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178

G

cytochrome P450, family 2, subfamily e, polypeptide 1

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:20843640 PMID:29404441

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

G

discoidin domain receptor tyrosine kinase 1

severity

mRNA:increased expression:liver (human)

RGD

NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468

G

discoidin domain receptor tyrosine kinase 2

disease_progression
ameliorates

RGD

PMID:21199726 PMID:23409069

RGD:150429766, RGD:150517731

NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363

G

fatty acid binding protein 2

onset

DNA:polymorphism:CDS:amino acid A54T, homozygosity of the T allele associated with later onset

PMID:16289894 PMID:16289894

RGD:1578455, RGD:1578455

NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089

G

gamma-aminobutyric acid type A receptor subunit gamma 2

susceptibility

DNA:SNP:intron 8:84435G>A (human)

RGD

NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346

G

interleukin 18 binding protein

protein:increased expression:plasma:

RGD

NCBI chr 1:156,372,923...156,374,963
Ensembl chr 1:156,372,883...156,374,963

G

interleukin 6

CTD Direct Evidence: marker/mechanism

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

Janus kinase 2

mRNA, protein:increased expression, increased tyrosine phosphorylation:liver

RGD

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

G

leptin

DNA:hypomethylation:promoter (human)

RGD

NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262

G

membrane bound O-acyltransferase domain containing 7

CTD Direct Evidence: marker/mechanism

NCBI chr 1:65,525,206...65,539,538
Ensembl chr 1:65,525,213...65,539,538

G

microRNA 122

miRNA:decreased expression:liver

RGD

NCBI chr18:58,758,703...58,758,787

G

microRNA 141

CTD Direct Evidence: marker/mechanism

NCBI chr 4:157,523,239...157,523,332
Ensembl chr 4:157,523,239...157,523,332

G

microRNA 17

CTD Direct Evidence: marker/mechanism

NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712

G

microRNA 193b

CTD Direct Evidence: marker/mechanism

NCBI chr10:1,317,742...1,317,824
Ensembl chr10:1,317,742...1,317,824

G

microRNA 423

CTD Direct Evidence: marker/mechanism

NCBI chr10:61,914,142...61,914,220
Ensembl chr10:61,914,133...61,914,226

G

microRNA 484

CTD Direct Evidence: marker/mechanism

NCBI chr10:887,684...887,760
Ensembl chr10:887,684...887,760

G

microRNA 532

CTD Direct Evidence: marker/mechanism

NCBI chr X:15,247,315...15,247,393
Ensembl chr X:15,247,315...15,247,393

G

microRNA 93

CTD Direct Evidence: marker/mechanism

NCBI chr12:17,043,135...17,043,221
Ensembl chr12:17,043,135...17,043,221

G

matrix metallopeptidase 13

RGD

NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239

G

matrix metallopeptidase 2

CTD Direct Evidence: marker/mechanism

NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870

G

myeloperoxidase

CTD Direct Evidence: marker/mechanism

PMID:19731237 PMID:23274713

NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819

G

methylenetetrahydrofolate reductase

susceptibility

DNA:SNP: :677C>T(human)

RGD

NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797

G

nuclear receptor subfamily 1, group D, member 1

RGD

NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705

G

plasminogen activator, urokinase

RGD

NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775

G

patatin-like phospholipase domain containing 3

CTD Direct Evidence: marker/mechanism

PMID:19946271 PMID:26482880

NCBI chr 7:115,293,538...115,314,077
Ensembl chr 7:115,293,538...115,314,077

G

RELA proto-oncogene, NF-kB subunit

CTD Direct Evidence: marker/mechanism

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

serpin family E member 1

susceptibility

DNA:polymorphism:promoter:

RGD

NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657

G

serpin family F member 1

protein:increased expression:serum (human)

RGD

NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646

G

SMAD family member 3

CTD Direct Evidence: marker/mechanism

NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960

G

superoxide dismutase 2

susceptibility

CTD Direct Evidence: marker/mechanism
DNA:SNP: : 47T>C(human)

CTD
RGD

PMID:19731237 PMID:26873981

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

G

thyroglobulin

RGD

NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210

G

transforming growth factor, beta 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

G

TIMP metallopeptidase inhibitor 1

CTD Direct Evidence: marker/mechanism

NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664

G

toll-like receptor 9

protein:increased expression:blood, neutrophil (human)

RGD

NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796

G

transmembrane 6 superfamily member 2

CTD Direct Evidence: marker/mechanism

NCBI chr16:19,344,218...19,351,431
Ensembl chr16:19,344,222...19,351,431

G

tumor necrosis factor

CTD Direct Evidence: marker/mechanism

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

Alpers-Huttenlocher syndrome

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aquaporin 4

RGD

NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856

G

ectodysplasin-A receptor

ClinVar Annotator: match by term: Progressive sclerosing poliodystrophy

PMID:10431241 PMID:18231121 PMID:20236127 PMID:20979233 PMID:25741868 More...

NCBI chr20:26,587,836...26,666,543
Ensembl chr20:26,587,839...26,666,494

G

FA complementation group I

ClinVar Annotator: match by term: Progressive sclerosing poliodystrophy

PMID:15477547 PMID:15689359 PMID:16177225 PMID:16621917 PMID:17088268 More...

NCBI chr 1:133,327,264...133,383,661
Ensembl chr 1:133,327,297...133,383,640

G

DNA polymerase gamma, catalytic subunit

susceptibility

DNA:mutations:cds:
ClinVar Annotator: match by term: Alpers-Huttenlocher Syndrome | ClinVar Annotator: match by term: Mitochondrial DNA depletion syndrome 4a | ClinVar Annotator: match by term: Neuronal degeneration of childhood with liver disease, progressive | ClinVar Annotator: match by term: Progressive sclerosing poliodystrophy
ClinVar Annotator: match by term: Alpers progressive infantile poliodystrophy | ClinVar Annotator: match by term: Alpers-Huttenlocher Syndrome | ClinVar Annotator: match by term: Mitochondrial DNA depletion syndrome 4a | ClinVar Annotator: match by term: Neuronal degeneration of childhood with liver disease, progressive | ClinVar Annotator: match by term: Progressive sclerosing poliodystrophy
ClinVar Annotator: match by term: Alpers diffuse degeneration of cerebral gray matter with hepatic cirrhosis | ClinVar Annotator: match by term: Alpers-Huttenlocher Syndrome | ClinVar Annotator: match by term: Mitochondrial DNA depletion syndrome 4A (Alpers type) | ClinVar Annotator: match by term: Mitochondrial DNA depletion syndrome 4a | ClinVar Annotator: match by term: Neuronal degeneration of childhood with liver disease, progressive | ClinVar Annotator: match by term: Progressive sclerosing poliodystrophy
ClinVar Annotator: match by term: Alpers diffuse degeneration of cerebral gray matter with hepatic cirrhosis | ClinVar Annotator: match by term: Alpers-Huttenlocher Syndrome | ClinVar Annotator: match by term: Mitochondrial DNA depletion syndrome 4a | ClinVar Annotator: match by term: Neuronal degeneration of childhood with liver disease, progressive | ClinVar Annotator: match by term: Progressive sclerosing poliodystrophy
ClinVar Annotator: match by term: Alpers Syndrome | ClinVar Annotator: match by term: Alpers-Huttenlocher Syndrome | ClinVar Annotator: match by term: Mitochondrial DNA depletion syndrome 4a | ClinVar Annotator: match by term: Neuronal degeneration of childhood with liver disease, progressive | ClinVar Annotator: match by term: Progressive sclerosing poliodystrophy
DNA:missense mutation:cds:p.P1073L (3218C>T) (human)
CTD Direct Evidence: marker/mechanism
DNA:missense mutations:cds:

ClinVar
CTD
OMIM
RGD

PMID:632821 PMID:1539879 PMID:1582434 PMID:1858914 PMID:2067633 More...

RGD:8694184, RGD:15039298, RGD:8694317, RGD:8694284

NCBI chr 1:133,382,764...133,399,578
Ensembl chr 1:133,382,766...133,398,567

G

RNA polymerase mitochondrial

ClinVar Annotator: match by term: Progressive sclerosing poliodystrophy

NCBI chr 7:9,959,532...9,969,791
Ensembl chr 7:9,959,576...9,969,791

G

RAN binding protein 2

ClinVar Annotator: match by term: Progressive sclerosing poliodystrophy

PMID:10431241 PMID:18231121 PMID:20236127 PMID:20979233 PMID:25741868 More...

NCBI chr20:26,442,156...26,493,481
Ensembl chr20:26,442,217...26,493,481

G

retinaldehyde binding protein 1

ClinVar Annotator: match by term: Progressive sclerosing poliodystrophy

PMID:2392416 PMID:11301032 PMID:21447491 PMID:25429852 PMID:28492532

NCBI chr 1:133,308,920...133,322,296
Ensembl chr 1:133,308,938...133,322,296

Banti's Syndrome

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

angiotensin I converting enzyme

protein:increased expression:serum (human)

RGD

NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131

G

integrin subunit beta 3

DNA:missense mutation: :p.L33P (human)

RGD

NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679

G

methylenetetrahydrofolate reductase

susceptibility

DNA:SNPs: :DNA:SNPs: :677C>T, 1298A>C(human)

RGD

NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797

G

serpin family E member 1

susceptibility

DNA:polymorphism:promoter:

RGD

NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657

Cardiac Fibrosis

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acetyl-CoA carboxylase beta

mRNA, protein:increased expression:heart (rat)

RGD

NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655

G

angiotensin converting enzyme 2

treatment

associated with Hypertension

RGD

NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977

G

advanced glycosylation end product-specific receptor

treatment

associated with Diabetes Mellitus, Experimental; protein:increased expression:cardiac atrium (rat)

RGD

PMID:21802905 PMID:24630381

RGD:7245957, RGD:8696003

NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078

G

aryl hydrocarbon receptor

treatment

RGD

NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568

G

aryl hydrocarbon receptor nuclear translocator

treatment

RGD

NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580

G

alpha-2-glycoprotein 1, zinc-binding

exacerbates

RGD

NCBI chr12:16,930,990...16,939,333
Ensembl chr12:16,931,024...16,939,091

G

collagen type I alpha 1 chain

treatment

associated with Hypertension;mRNA:increased expression:heart
protein:increased expression:blood serum (rat)

RGD

PMID:21769867 PMID:27318893 PMID:19019833

RGD:5688337, RGD:156430318, RGD:8552780

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

G

collagen type III alpha 1 chain

protein:increased expression:blood serum (rat)

RGD

NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547

G

carnitine palmitoyltransferase 1A

mRNA, protein:decreased expression:heart (rat)

RGD

NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055

G

colony stimulating factor 3

associated with Myocardial Infarction;

RGD

NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603

G

cytochrome P450, family 1, subfamily a, polypeptide 1

treatment

RGD

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily b, polypeptide 1

treatment

RGD

NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917

G

dystrophin

RGD

NCBI chr X:47,272,324...49,504,219
Ensembl chr X:47,272,331...49,504,207

G

dystrophin; TALEN-induced mutant1, Ang

RGD

G

desmoglein 2

disease_progression

RGD

NCBI chr18:11,846,207...11,904,630
Ensembl chr18:11,846,183...11,904,156

G

dual specificity phosphatase 5

mRNA,protein:decreased expression:cardiac muscle tissue (rat)

RGD

NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818

G

endothelin 1

treatment

RGD

NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885

G

coagulation factor III, tissue factor

RGD

NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668

G

fatty acid desaturase 1

treatment

RGD

NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734

G

fatty acid desaturase 2

treatment

RGD

PMID:24284026 PMID:22796714

RGD:401901245, RGD:401901592

NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789

G

fibrillin 1

associated with Hypertension;protein:increased expression:myocardium

RGD

NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889

G

fibronectin 1

mRNA, protein:increased expression:heart:

RGD

NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678

G

ghrelin and obestatin prepropeptide

disease_progression
treatment

mRNA,protein:increased expression:plasma,myocardia:

RGD

PMID:16626506 PMID:16626506

RGD:12907503, RGD:12907503

NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621

G

growth hormone secretagogue receptor

mRNA,protein:increased expression,increased activity:myocardia:

RGD

NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865

G

gap junction protein, alpha 1

protein:decreased expression:myocardium

RGD

NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582

G

glutathione-disulfide reductase

treatment

RGD

NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661

G

glutathione S-transferase mu 2

treatment

RGD

NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961

G

glutathione S-transferase mu 3

treatment

RGD

NCBI chr 2:195,590,450...195,612,578
Ensembl chr 2:195,607,289...195,612,475

G

H19 imprinted maternally expressed transcript

mRNA:increased expression:cardiac muscle tissue (rat)

RGD

NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134

G

histone cell cycle regulator

disease_progression

RGD

NCBI chr11:82,024,469...82,133,212
Ensembl chr11:82,024,469...82,133,529

G

histidine rich calcium binding protein

severity

associated with Heart Failure

RGD

NCBI chr 1:95,813,262...95,816,987
Ensembl chr 1:95,813,253...95,816,984

G

potassium calcium-activated channel subfamily N member 4

ameliorates

RGD

PMID:30563389 PMID:28455747

RGD:401700380, RGD:401700389

NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340

G

latent transforming growth factor beta binding protein 2

mRNA:increased expression:heart (mouse)

RGD

NCBI chr 6:104,429,947...104,530,498
Ensembl chr 6:104,429,947...104,526,208

G

mitogen activated protein kinase kinase kinase 7

treatment

associated with obesity;protein:increased phosphorylation:heart (mouse)

RGD

PMID:32543140 PMID:29143862

RGD:155791675, RGD:155804300

NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597

G

mitofusin 2

protein:decreased expression:heart (rat)

RGD

NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342

G

microRNA 221

severity

associated with dilated cardiomyopathy;

RGD

NCBI chr X:3,429,465...3,429,573
Ensembl chr X:3,429,465...3,429,573

G

microRNA 222

severity

associated with dilated cardiomyopathy;

RGD

PMID:27614440 PMID:29255073

RGD:151893489, RGD:18337269

NCBI chr X:3,428,904...3,429,006
Ensembl chr X:3,428,904...3,429,006

G

microRNA 223

treatment

associated with acute myocardial infarction;

RGD

NCBI chr X:61,141,887...61,141,996
Ensembl chr X:61,141,887...61,141,996

G

microRNA 30e

treatment

RGD

NCBI chr 5:134,352,232...134,352,323
Ensembl chr 5:134,352,232...134,352,323

G

microRNA 433

treatment

associated with myocardial infarction

RGD

PMID:27698941 PMID:27698941

RGD:14700802, RGD:14700802

NCBI chr 6:128,545,119...128,545,211
Ensembl chr 6:128,545,112...128,545,217

G

malonyl-CoA decarboxylase

protein:increased expression:heart (rat)

RGD

NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793

G

matrix metallopeptidase 7

associated with Heart Failure

RGD

NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902

G

matrix metallopeptidase 9

associated with Cardiomegaly;mRNA:increased expression:heart
associated with Arthritis, Experimental

RGD

PMID:23144938 PMID:23905389

RGD:13204817, RGD:13204857

NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120

G

NFE2 like bZIP transcription factor 2

treatment

RGD

NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737

G

NFKB inhibitor alpha

treatment

associated with Hypertension

RGD

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

nucleotide-binding oligomerization domain containing 1

RGD

NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404

G

non-POU domain containing, octamer-binding

RGD

NCBI chr X:66,554,131...66,571,992
Ensembl chr X:66,554,098...66,571,952

G

p21 (RAC1) activated kinase 1

RGD

NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383

G

pleckstrin homology domain containing A7

ameliorates

compared to wild type

RGD

PMID:25136115 PMID:25136115

RGD:11079199, RGD:11079199

NCBI chr 1:170,364,524...170,547,843
Ensembl chr 1:170,365,135...170,547,775

G

Plekha7^em4Mcwi

pleckstrin homology domain containing, family A member 7; zinc finger nuclease induced mutant 4, Medical College of Wisconsin

ameliorates

compared to wild type

RGD

PMID:25136115 PMID:25136115

RGD:11079199, RGD:11079199

G

protein kinase AMP-activated catalytic subunit alpha 2

protein:decreased expression:serum, heart (rat)

RGD

NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543

G

protein kinase D1

treatment

associated with Cardiomegaly

RGD

NCBI chr 6:67,725,193...68,039,002
Ensembl chr 6:67,725,905...68,039,042

G

roundabout guidance receptor 1

ameliorates

RGD

NCBI chr11:10,580,863...11,621,675
Ensembl chr11:10,580,908...11,620,203

G

serpin family E member 1

treatment

associated with Hypertension;mRNA, protein:increased expression:heart left ventricle (rat)
associated with Metabolic Syndrome X

RGD

PMID:11961044 PMID:15604340

RGD:8547914, RGD:8547923

NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657

G

solute carrier family 22 member 5

treatment

RGD

NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309

G

slit guidance ligand 2

protein:increased expression:left ventricle

RGD

NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948

G

transforming growth factor, beta 1

ameliorates

protein:increased expression:blood serum (rat)
protein:increased expression:heart:

RGD

PMID:22134166 PMID:33236535 PMID:27318893 PMID:27108788

RGD:11073617, RGD:242905189, RGD:156430318, RGD:11073667

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

G

UDP-glucose ceramide glucosyltransferase

treatment

RGD

NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393

Cholangiofibrosis

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

CD40 ligand

treatment

RGD

NCBI chr X:135,127,052...135,138,768
Ensembl chr X:135,126,969...135,138,306

G

glutathione S-transferase pi 1

RGD

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

isocitrate dehydrogenase (NADP(+)) 1

severity

associated with intrahepatic cholangiocarcinoma; DNA:missense mutations:cds:p. R132C, R132G, and R132L (human)

RGD

NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708

G

microRNA 192

RNA:increased expression:urine

RGD

NCBI chr 1:203,564,946...203,565,055
Ensembl chr 1:203,564,946...203,565,055

G

microRNA 21

RNA:increased expression:urine

RGD

NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348

Cicatrix

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

collagen type VII alpha 1 chain

ClinVar Annotator: match by term: Scarring

PMID:12787275 PMID:22266148 PMID:25741868 PMID:28492532 PMID:28830826 More...

NCBI chr 8:109,604,877...109,637,249
Ensembl chr 8:109,604,861...109,637,252

G

mitofusin 2

ClinVar Annotator: match by term: Scarring

PMID:15064763 PMID:16437557 PMID:16714318 PMID:16835246 PMID:17215403 More...

NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342

G

microRNA 494

ameliorates

RGD

NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793

G

matrix metallopeptidase 9

treatment

associated with Wounds, Penetrating

RGD

NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120

G

SMAD family member 4

treatment

RGD

NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438

congenital fibrosis of the extraocular muscles

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

catenin alpha 1

ClinVar Annotator: match by term: Congenital fibrosis of extraocular muscles

NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910

G

fibroblast growth factor 21

ClinVar Annotator: match by term: Congenital fibrosis of extraocular muscles

NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454

G

HRas proto-oncogene, GTPase

ClinVar Annotator: match by term: Congenital fibrosis of extraocular muscles

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

G

kinesin family member 21A

OMIM:135700 | OMIM:600638 | OMIM:602078 | OMIM:609384 | OMIM:609428 | OMIM:616219
ClinVar Annotator: match by term: Congenital fibrosis of extraocular muscles | ClinVar Annotator: match by term: OPHTHALMOPLEGIA, CONGENITAL

MouseDO
ClinVar

PMID:14595441 PMID:15621876 PMID:15621877 PMID:15827546 PMID:18332320 More...

NCBI chr 7:122,062,523...122,179,051
Ensembl chr 7:122,062,537...122,178,999

G

leucine rich repeat containing 56

ClinVar Annotator: match by term: Congenital fibrosis of extraocular muscles

NCBI chr 1:196,299,843...196,315,170
Ensembl chr 1:196,299,846...196,315,172

G

minichromosome maintenance complex component 3 associated protein

ClinVar Annotator: match by term: Congenital fibrosis of extraocular muscles

PMID:25741868 PMID:39033378

NCBI chr20:12,127,570...12,165,165
Ensembl chr20:12,127,570...12,165,165

G

myosin heavy chain 10

ClinVar Annotator: match by term: Congenital fibrosis of extraocular muscles

NCBI chr10:53,393,901...53,525,174
Ensembl chr10:53,394,389...53,525,165

G

nestin

ClinVar Annotator: match by term: Congenital fibrosis of extraocular muscles

NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777

G

tubulin, alpha 1A

ClinVar Annotator: match by term: Congenital fibrosis of extraocular muscles

NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186

G

tubulin, alpha 1B

ClinVar Annotator: match by term: Congenital fibrosis of extraocular muscles

PMID:25741868 PMID:39033378

NCBI chr 7:130,090,663...130,093,644
Ensembl chr 7:130,081,032...130,196,186

G

tubulin, beta 3 class III

OMIM:135700 | OMIM:600638 | OMIM:602078 | OMIM:609384 | OMIM:609428 | OMIM:616219
ClinVar Annotator: match by term: Congenital fibrosis of extraocular muscles

MouseDO
ClinVar

NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243

G

tubulin, beta 5 class I

ClinVar Annotator: match by term: Congenital fibrosis of extraocular muscles

PMID:25741868 PMID:39033378

NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940

congenital fibrosis of the extraocular muscles 1

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

kinesin family member 21A

DNA:missense mutation:CDS:2860C>T (p.R954W) (human)
ClinVar Annotator: match by term: BLEPHAROPTOSIS WITH ABSENT EYE MOVEMENTS | ClinVar Annotator: match by term: Fibrosis of extraocular muscles, congenital, 3b | ClinVar Annotator: match by term: KIF21A-related condition
CTD Direct Evidence: marker/mechanism

ClinVar
CTD
OMIM
RGD

PMID:10922204 PMID:14595441 PMID:15223798 PMID:15621876 PMID:15621877 More...

NCBI chr 7:122,062,523...122,179,051
Ensembl chr 7:122,062,537...122,178,999

congenital fibrosis of the extraocular muscles 2

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

paired-like homeobox 2a

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Fibrosis of extraocular muscles, congenital, 2

OMIM
CTD
ClinVar

PMID:11600883 PMID:25741868

NCBI chr 1:156,178,754...156,183,118
Ensembl chr 1:156,178,754...156,183,118

congenital fibrosis of the extraocular muscles 3A

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

tubulin, beta 3 class III

ClinVar Annotator: match by term: Fibrosis of extraocular muscles, congenital, 3A, with or without extraocular involvement | ClinVar Annotator: match by term: TUBB3-related disorder | ClinVar Annotator: match by term: TUBB3-related tubulinopathy
CTD Direct Evidence: marker/mechanism

OMIM
ClinVar
CTD

PMID:2133536 PMID:7724178 PMID:10393037 PMID:12073023 PMID:15223798 More...

NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243

congenital fibrosis of the extraocular muscles 5

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

collagen type XXV alpha 1 chain

ClinVar Annotator: match by term: Fibrosis of extraocular muscles, congenital, 5

PMID:25500261 PMID:25741868 PMID:31875546

NCBI chr 2:218,755,152...219,154,348
Ensembl chr 2:218,755,691...219,153,501

Congenital Hepatic Fibrosis

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

angiotensin I converting enzyme

associated with Polycystic Kidney, Autosomal Recessive;mRNA:increased expression:liver

RGD

NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131

G

interferon, lambda 3

CTD Direct Evidence: marker/mechanism

NCBI chr 1:83,814,456...83,816,096
Ensembl chr 1:83,814,564...83,816,096

G

PKHD1 ciliary IPT domain containing fibrocystin/polyductin

DNA:mutations:cds:c.7994T>C, p.(Leu2665Pro),c.8518C>T, p.(Arg2840Cys)(human)

RGD

PMID:30600684 PMID:30507656

RGD:14700919, RGD:14700992

NCBI chr 9:22,547,396...23,037,443
Ensembl chr 9:22,549,513...23,037,381

Cryptogenic Cirrhosis

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cytotoxic T-lymphocyte-associated protein 4

susceptibility

DNA:SNP: :-318C>T(human)

RGD

NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963

G

keratin 18

ClinVar Annotator: match by term: Cirrhosis, cryptogenic

PMID:9011570 PMID:12724528

NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166

G

keratin 8

ClinVar Annotator: match by term: Cirrhosis, cryptogenic

PMID:9011570 PMID:11372009 PMID:12724528 PMID:15235035 PMID:28492532 More...

NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728

Dermal Fibrosis

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

caveolin 1

RGD

NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705

G

serpin family E member 1

treatment

RGD

NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657

G

signal transducer and activator of transcription 4

RGD

NCBI chr 9:49,472,660...49,588,540
Ensembl chr 9:49,419,340...49,588,540

diffuse pulmonary fibrosis

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily A member 3

ClinVar Annotator: match by term: Diffuse interstitial pulmonary fibrosis

PMID:15976379 PMID:17597647 PMID:18246475 PMID:18317237 PMID:18603241 More...

NCBI chr10:13,382,439...13,439,748
Ensembl chr10:13,382,540...13,439,745

Experimental Liver Cirrhosis

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha-2-macroglobulin

CTD Direct Evidence: marker/mechanism

NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786

G

arylacetamide deacetylase

CTD Direct Evidence: marker/mechanism

NCBI chr 2:144,163,436...144,186,086
Ensembl chr 2:144,135,319...144,174,734

G

aminoadipate aminotransferase

CTD Direct Evidence: marker/mechanism

NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332

G

4-aminobutyrate aminotransferase

CTD Direct Evidence: marker/mechanism

NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835

G

ATP binding cassette subfamily B member 1A

CTD Direct Evidence: marker/mechanism

PMID:16182555 PMID:17072980

NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709

G

ATP binding cassette subfamily C member 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238

G

ATP binding cassette subfamily C member 5

CTD Direct Evidence: marker/mechanism

NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253

G

ATP binding cassette subfamily G member 1

CTD Direct Evidence: marker/mechanism

NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948

G

ATP binding cassette subfamily G member 5

CTD Direct Evidence: marker/mechanism

NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563

G

ATP binding cassette subfamily G member 8

CTD Direct Evidence: marker/mechanism

NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912

G

actin binding LIM protein family, member 3

CTD Direct Evidence: marker/mechanism

NCBI chr18:55,256,135...55,376,629
Ensembl chr18:55,257,583...55,376,380

G

acetyl-CoA acetyltransferase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855

G

acyl-CoA binding domain containing 4

CTD Direct Evidence: marker/mechanism

NCBI chr10:88,048,058...88,062,612
Ensembl chr10:88,048,108...88,058,500

G

angiotensin I converting enzyme

severity

mRNA: increased expression:liver (rat)
protein:increased activity:plasma (human)
mRNA:increased expression:liver (rat)

RGD

PMID:19424597 PMID:8445218 PMID:23663763 PMID:24035938

RGD:25671449, RGD:25671458, RGD:25671457, RGD:21408579

NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131

G

angiotensin converting enzyme 2

protein:increased expression:liver
mRNA, protein:increased expression, increased activity:liver (rat)

RGD

PMID:19793108 PMID:16166274

RGD:2316776, RGD:40818265

NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977

G

acetylcholinesterase

CTD Direct Evidence: marker/mechanism

NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651

G

atypical chemokine receptor 3

CTD Direct Evidence: marker/mechanism

NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237

G

acyl-CoA thioesterase 9

CTD Direct Evidence: marker/mechanism

NCBI chr X:40,073,197...40,123,573
Ensembl chr X:40,064,810...40,123,559

G

acyl-CoA oxidase 2

CTD Direct Evidence: marker/mechanism

NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160

G

acid phosphatase 5, tartrate resistant

CTD Direct Evidence: marker/mechanism

NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929

G

acyl-CoA synthetase long-chain family member 1

CTD Direct Evidence: marker/mechanism

NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541

G

actin alpha 2, smooth muscle

CTD Direct Evidence: marker/mechanism
associated with Schistosomiasis Japonica; mRNA:increased expression:liver (rat)

CTD
RGD

PMID:26435214 PMID:26739621 PMID:29323718

NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554

G

actinin, alpha 1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251

G

activin A receptor type 2A

mRNA:decreased expression:liver

RGD

NCBI chr 3:33,204,961...33,292,673
Ensembl chr 3:33,205,523...33,289,968

G

adenosine deaminase

CTD Direct Evidence: marker/mechanism

NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088

G

ADAM metallopeptidase domain 17

CTD Direct Evidence: marker/mechanism

NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639

G

adducin 3

CTD Direct Evidence: marker/mechanism

NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124

G

adhesion G protein-coupled receptor E1

CTD Direct Evidence: marker/mechanism

NCBI chr 9:2,242,476...2,398,000
Ensembl chr 9:2,242,474...2,398,000

G

alcohol dehydrogenase 1C (class I), gamma polypeptide

CTD Direct Evidence: marker/mechanism

NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892

G

alcohol dehydrogenase 4 (class II), pi polypeptide

CTD Direct Evidence: marker/mechanism

NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591

G

alcohol dehydrogenase, iron containing, 1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:9,705,966...9,732,580
Ensembl chr 5:9,705,970...9,732,517

G

adiponectin, C1Q and collagen domain containing

CTD Direct Evidence: therapeutic

NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564

G

adiponectin receptor 2

severity

RGD

NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355

G

adrenomedullin

protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:15370692 PMID:16610064 PMID:16713642

NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654

G

adenosine A2a receptor

CTD Direct Evidence: marker/mechanism

NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386

G

adenosine A3 receptor

CTD Direct Evidence: marker/mechanism

NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357

G

adrenoceptor alpha 1B

CTD Direct Evidence: marker/mechanism

NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919

G

adrenoceptor beta 1

mRNA, protein:increased expression:liver

RGD

NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259

G

adrenoceptor beta 2

mRNA, protein:increased expression:liver

RGD

NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512

G

adrenoceptor beta 3

mRNA, protein:increased expression:liver

RGD

NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552

G

apoptosis enhancing nuclease

CTD Direct Evidence: marker/mechanism

NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523

G

afamin

CTD Direct Evidence: marker/mechanism

NCBI chr14:17,531,022...17,563,868
Ensembl chr14:17,531,024...17,563,870

G

alpha-fetoprotein

treatment

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:17072980 PMID:30346985

NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480

G

ArfGAP with FG repeats 1

CTD Direct Evidence: marker/mechanism

NCBI chr 9:84,124,845...84,182,615
Ensembl chr 9:84,125,120...84,178,128

G

amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase

CTD Direct Evidence: marker/mechanism

NCBI chr 2:204,705,053...204,760,966
Ensembl chr 2:204,705,053...204,760,828

G

angiotensinogen

CTD Direct Evidence: marker/mechanism

NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977

G

angiotensin II receptor, type 1a

treatment

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:12890498 PMID:25380136 PMID:24619965

NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946

G

AHNAK nucleoprotein

CTD Direct Evidence: marker/mechanism

NCBI chr 1:205,882,225...205,970,934
Ensembl chr 1:205,882,273...205,970,926

G

axin interactor, dorsalization associated

CTD Direct Evidence: marker/mechanism

NCBI chr13:94,940,311...94,967,920
Ensembl chr13:94,939,741...94,967,920

G

allograft inflammatory factor 1

CTD Direct Evidence: marker/mechanism

NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668

G

aldo-keto reductase family 1 member B1

CTD Direct Evidence: marker/mechanism

NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157

G

aldo-keto reductase family 1, member C1

CTD Direct Evidence: marker/mechanism

NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326

G

aldo-keto reductase family 1, member C3

CTD Direct Evidence: marker/mechanism

NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873

G

aldo-keto reductase family 1 member C3-like 1

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr17:65,847,580...65,881,488
Ensembl chr17:65,835,634...65,881,488

G

AKT interacting protein

CTD Direct Evidence: marker/mechanism

NCBI chr19:15,866,811...15,877,123
Ensembl chr19:15,866,928...15,886,663

G

albumin

treatment

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:16642209 PMID:17963606 PMID:21163135 PMID:30346985

NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836

G

aldehyde dehydrogenase 1 family, member A1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961

G

aldehyde dehydrogenase 1 family, member B1

CTD Direct Evidence: marker/mechanism

PMID:15650968 PMID:25380136

NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378

G

aldehyde dehydrogenase 1 family, member L1

CTD Direct Evidence: marker/mechanism

NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465

G

aldehyde dehydrogenase 1 family, member L2

CTD Direct Evidence: marker/mechanism

NCBI chr 7:20,254,246...20,305,793
Ensembl chr 7:20,254,233...20,305,776

G

aldehyde dehydrogenase 2 family member

CTD Direct Evidence: marker/mechanism

NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521

G

alpha-methylacyl-CoA racemase

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255

G

angiopoietin 1

disease_progression

protein:increased expression:liver

RGD

NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067

G

angiopoietin 2

mRNA, protein:increased expression:multiple organs (rat)

RGD

NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804

G

angiopoietin-like 3

CTD Direct Evidence: marker/mechanism

NCBI chr 5:113,703,007...113,710,044
Ensembl chr 5:113,703,012...113,709,957

G

anoctamin 6

CTD Direct Evidence: marker/mechanism

NCBI chr 7:126,933,919...127,113,588
Ensembl chr 7:126,933,936...127,113,589

G

acidic nuclear phosphoprotein 32 family member A

treatment

RGD

NCBI chr 8:62,829,099...62,865,443
Ensembl chr 8:62,827,456...62,865,443

G

annexin A1

mRNA:increased expression:liver
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:25380136 PMID:8755646

NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343

G

annexin A2

CTD Direct Evidence: marker/mechanism

NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658

G

annexin A3

CTD Direct Evidence: marker/mechanism

NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617

G

annexin A4

CTD Direct Evidence: marker/mechanism

NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161

G

annexin A5

CTD Direct Evidence: marker/mechanism

NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369

G

adaptor related protein complex 1 subunit sigma 2

CTD Direct Evidence: marker/mechanism

NCBI chr X:30,572,746...30,598,961
Ensembl chr X:30,572,751...30,597,262

G

adaptor related protein complex 3 subunit sigma 1

CTD Direct Evidence: marker/mechanism

NCBI chr18:39,462,728...39,531,622
Ensembl chr18:39,462,765...39,531,622

G

apoptotic peptidase activating factor 1

CTD Direct Evidence: marker/mechanism

NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540

G

amyloid beta precursor protein binding family B member 1 interacting protein

CTD Direct Evidence: marker/mechanism

NCBI chr17:84,941,404...85,033,020
Ensembl chr17:84,982,243...85,033,010

G

adipocyte plasma membrane associated protein

CTD Direct Evidence: marker/mechanism

NCBI chr 3:139,409,021...139,437,296
Ensembl chr 3:139,409,022...139,437,341

G

apolipoprotein A1

RGD

NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035

G

apolipoprotein A4

CTD Direct Evidence: marker/mechanism

NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469

G

apolipoprotein B mRNA editing enzyme catalytic subunit 1

CTD Direct Evidence: marker/mechanism

NCBI chr 4:155,800,030...155,828,515
Ensembl chr 4:155,800,887...155,827,390

G

apolipoprotein L9a

CTD Direct Evidence: marker/mechanism

NCBI chr 7:109,140,871...109,149,799
Ensembl chr 7:109,140,871...109,147,649

G

amyloid beta precursor protein

CTD Direct Evidence: marker/mechanism

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

G

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1

CTD Direct Evidence: marker/mechanism

NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692

G

aquaporin 7

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642

G

arginase 1

mRNA, protein:decreased expression:liver (rat)

RGD

NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422

G

arginase 2

mRNA, protein:increased expression:liver

RGD

NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378

G

Rho GTPase activating protein 30

CTD Direct Evidence: marker/mechanism

NCBI chr13:83,822,290...83,843,634
Ensembl chr13:83,822,283...83,854,885

G

Rho GTPase activating protein 9

CTD Direct Evidence: marker/mechanism

NCBI chr 7:63,148,573...63,157,025
Ensembl chr 7:63,148,900...63,157,524

G

Rho GDP dissociation inhibitor beta

CTD Direct Evidence: marker/mechanism

NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658

G

ADP-ribosylation factor like GTPase 11

CTD Direct Evidence: marker/mechanism

NCBI chr15:35,483,330...35,485,579
Ensembl chr15:35,480,018...35,496,596

G

ADP-ribosylation factor like GTPase 8A

CTD Direct Evidence: marker/mechanism

NCBI chr13:46,585,845...46,594,851
Ensembl chr13:46,585,845...46,594,851

G

armadillo repeat containing, X-linked 1

CTD Direct Evidence: marker/mechanism

NCBI chr X:97,898,969...97,902,874
Ensembl chr X:97,898,883...97,903,299

G

actin related protein 2/3 complex, subunit 1B

CTD Direct Evidence: marker/mechanism

NCBI chr12:9,482,176...9,495,772
Ensembl chr12:9,480,831...9,495,747

G

arrestin, beta 2

CTD Direct Evidence: marker/mechanism
protein:increased expression:aorta

CTD
RGD

PMID:25380136 PMID:17256744

NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850

G

N-acylsphingosine amidohydrolase 1

CTD Direct Evidence: marker/mechanism

NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233

G

asparagine synthetase (glutamine-hydrolyzing)

CTD Direct Evidence: marker/mechanism

NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423

G

asporin

CTD Direct Evidence: marker/mechanism

NCBI chr17:15,079,910...15,104,369
Ensembl chr17:15,080,639...15,104,041

G

argininosuccinate synthase 1

mRNA:decreased expression:liver (rat)

RGD

NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903

G

activating transcription factor 3

CTD Direct Evidence: marker/mechanism

NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631

G

ATPase phospholipid transporting 10D (putative)

CTD Direct Evidence: marker/mechanism

NCBI chr14:35,911,728...36,012,549
Ensembl chr14:35,912,141...36,012,564

G

ATPase H+ transporting V1 subunit D

CTD Direct Evidence: marker/mechanism

NCBI chr 6:97,656,725...97,672,295
Ensembl chr 6:97,656,576...97,672,303

G

attractin

CTD Direct Evidence: marker/mechanism

NCBI chr 3:118,110,320...118,244,326
Ensembl chr 3:118,110,229...118,244,322

G

Axl receptor tyrosine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265

G

beta-2 microglobulin

protein:increased expression:urine

RGD

NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766

G

beta-1,4-galactosyltransferase 5

CTD Direct Evidence: marker/mechanism

NCBI chr 3:156,018,056...156,033,983
Ensembl chr 3:156,018,053...156,070,074

G

B9 domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:46,186,222...46,196,309
Ensembl chr10:46,186,691...46,196,008

G

BCL2-antagonist/killer 1

mRNA:increased expression:liver

RGD

NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264

G

gamma-butyrobetaine hydroxylase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458

G

BCL2, apoptosis regulator

treatment

mRNA:increased expression:liver (rat)

RGD

PMID:24218972 PMID:17938867

RGD:10054116, RGD:2293129

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

BCR activator of RhoGEF and GTPase

CTD Direct Evidence: marker/mechanism

NCBI chr20:13,469,325...13,596,942
Ensembl chr20:13,471,668...13,597,016

G

3-hydroxybutyrate dehydrogenase 1

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671

G

biglycan

CTD Direct Evidence: marker/mechanism

NCBI chr X:151,197,296...151,209,458
Ensembl chr X:151,197,273...151,209,461

G

BICD cargo adaptor 2

CTD Direct Evidence: marker/mechanism

NCBI chr17:15,259,773...15,304,889
Ensembl chr17:15,259,773...15,304,889

G

baculoviral IAP repeat-containing 3

CTD Direct Evidence: marker/mechanism

NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802

G

baculoviral IAP repeat-containing 5

RGD

NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380

G

biogenesis of lysosomal organelles complex-1, subunit 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:243,024,611...243,031,749
Ensembl chr 1:243,024,614...243,031,653

G

biliverdin reductase A

CTD Direct Evidence: marker/mechanism

NCBI chr 3:114,340,778...114,366,048
Ensembl chr 3:114,340,838...114,366,033

G

Bcl2 modifying factor

CTD Direct Evidence: marker/mechanism

NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145

G

bone morphogenetic protein 4

mRNA, protein:increased expression:liver

RGD

NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306

G

bone morphogenetic protein 7

CTD Direct Evidence: therapeutic

NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788

G

similar to human chromosome 3 open reading frame 70

CTD Direct Evidence: marker/mechanism

NCBI chr11:79,345,857...79,396,140
Ensembl chr11:79,345,304...79,396,142

G

similar to human chromosome 1 open reading frame 21

CTD Direct Evidence: marker/mechanism

NCBI chr13:63,982,587...64,199,676
Ensembl chr13:63,990,592...64,199,596

G

complement C1q A chain

CTD Direct Evidence: marker/mechanism

NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534

G

complement C1q B chain

CTD Direct Evidence: marker/mechanism

NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407

G

complement C1q C chain

CTD Direct Evidence: marker/mechanism

NCBI chr 5:149,127,412...149,130,757
Ensembl chr 5:149,127,415...149,131,017

G

complement C5a receptor 1

treatment

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:25380136 PMID:15995705

NCBI chr 1:76,948,622...76,959,826

G

similar to human chromosome 1 open reading frame 210

CTD Direct Evidence: marker/mechanism

NCBI chr 5:132,048,755...132,051,913
Ensembl chr 5:132,048,773...132,051,925

G

complement C7

CTD Direct Evidence: marker/mechanism

NCBI chr 2:54,088,116...54,165,102
Ensembl chr 2:54,088,116...54,158,535

G

complement C8 gamma chain

CTD Direct Evidence: marker/mechanism

NCBI chr 3:8,320,503...8,322,087
Ensembl chr 3:8,305,920...8,323,495

G

similar to human chromosome 11 open reading frame 54

CTD Direct Evidence: marker/mechanism

NCBI chr 8:12,123,839...12,146,412
Ensembl chr 8:12,123,823...12,146,473

G

calcium/calmodulin-dependent protein kinase II delta

CTD Direct Evidence: marker/mechanism

NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178

G

capping actin protein, gelsolin like

CTD Direct Evidence: marker/mechanism

NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856

G

carbonic anhydrase 3

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280

G

carbonic anhydrase 5A

CTD Direct Evidence: marker/mechanism

NCBI chr19:49,973,092...50,002,948
Ensembl chr19:49,973,107...50,002,906

G

caspase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383

G

caspase 12

protein:increased expression:liver
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:25380136 PMID:16092975

NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037

G

caspase 4

CTD Direct Evidence: marker/mechanism

NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092

G

caspase 7

CTD Direct Evidence: marker/mechanism

NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729

G

caveolin 1

CTD Direct Evidence: marker/mechanism

NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705

G

coiled-coil domain containing 126

CTD Direct Evidence: marker/mechanism

NCBI chr 4:78,297,625...78,318,655
Ensembl chr 4:78,297,551...78,318,655

G

C-C motif chemokine ligand 2

treatment

CTD Direct Evidence: marker/mechanism
human gene in rat model

CTD
RGD

PMID:15492853 PMID:19144177 PMID:28437891 PMID:15492853

RGD:2307001, RGD:14995945, RGD:8549576

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

C-C motif chemokine ligand 5

treatment
disease_progression
severity

CTD Direct Evidence: marker/mechanism
mRNA,protein:increased expression:liver

CTD
RGD

PMID:25380136 PMID:22574195 PMID:25617348 PMID:20978355 PMID:20978355

RGD:14995337, RGD:14995329, RGD:14995328, RGD:14995328

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

G

C-C motif chemokine ligand 7

RGD

NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303

G

C-C motif chemokine ligand 9

CTD Direct Evidence: marker/mechanism

NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369

G

cellular communication network factor 2

mRNA:increased expression:liver (rat)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:25380136 PMID:19856102

NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734

G

cellular communication network factor 4

RGD

NCBI chr 7:98,645,238...98,677,253
Ensembl chr 7:98,645,182...98,677,248

G

cyclin A2

CTD Direct Evidence: marker/mechanism

NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577

G

cyclin B2

CTD Direct Evidence: marker/mechanism

NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874

G

cyclin G1

CTD Direct Evidence: marker/mechanism

NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641

G

C-C motif chemokine receptor 5

treatment

mRNA,protein:increased expression:liver

RGD

PMID:19603542 PMID:19603542

RGD:14401743, RGD:14401743

NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260

G

CD163 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878

G

CD200 receptor 1

CTD Direct Evidence: marker/mechanism

NCBI chr11:55,886,937...55,921,217
Ensembl chr11:55,887,717...55,921,285

G

CD24 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662

G

Cd276 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr 8:58,937,751...58,968,082
Ensembl chr 8:58,937,751...58,968,380

G

CD36 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903

G

CD38 molecule

mRNA, protein:increased expression:liver
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:25380136 PMID:16343077

NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986

G

Cd48 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr13:84,184,884...84,209,144
Ensembl chr13:84,185,532...84,209,142

G

Cd53 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr 2:194,352,139...194,399,668
Ensembl chr 2:194,352,139...194,399,657

G

Cd5 molecule-like

CTD Direct Evidence: marker/mechanism

NCBI chr 2:172,791,007...172,802,018
Ensembl chr 2:172,790,934...172,829,753

G

Cd63 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr 7:1,325,108...1,340,447
Ensembl chr 7:1,325,103...1,399,178

G

Cd68 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697

G

Cd7 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr10:106,304,046...106,306,963
Ensembl chr10:106,304,056...106,306,967

G

CD74 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003

G

CD83 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083

G

CD86 molecule

CTD Direct Evidence: marker/mechanism

NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818

G

CDC42 small effector 1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:182,805,691...182,813,520
Ensembl chr 2:182,804,925...182,814,028

G

cadherin 1

associated with Schistosomiasis Japonica; mRNA:decreased expression:liver (rat)

RGD

NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775

G

cadherin 5

CTD Direct Evidence: marker/mechanism

NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368

G

cyclin-dependent kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408

G

cyclin dependent kinase 2

RGD

NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403

G

cyclin-dependent kinase 4

RGD

NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403

G

cyclin-dependent kinase inhibitor 1A

CTD Direct Evidence: marker/mechanism

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

CDKN2A interacting protein N-terminal like

CTD Direct Evidence: marker/mechanism

NCBI chr10:36,231,134...36,240,569
Ensembl chr10:36,231,087...36,240,564

G

cyclin-dependent kinase inhibitor 3

CTD Direct Evidence: marker/mechanism

NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945

G

cysteine dioxygenase type 1

CTD Direct Evidence: marker/mechanism

NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296

G

CCAAT/enhancer binding protein delta

CTD Direct Evidence: marker/mechanism

NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829

G

chymotrypsin like elastase 1

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr 7:131,773,161...131,786,300
Ensembl chr 7:131,742,002...131,786,285

G

CUGBP, Elav-like family member 2

CTD Direct Evidence: marker/mechanism

NCBI chr17:70,904,462...71,729,072
Ensembl chr17:71,210,853...71,728,333

G

cell migration inducing hyaluronidase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:219,330,295...219,407,760
Ensembl chr 1:219,337,985...219,407,760

G

ceramide kinase

CTD Direct Evidence: marker/mechanism

NCBI chr 7:117,225,855...117,269,436
Ensembl chr 7:117,225,855...117,268,759

G

carboxylesterase 2H

CTD Direct Evidence: marker/mechanism

NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830

G

carboxylesterase 3a

CTD Direct Evidence: marker/mechanism

NCBI chr19:32,992,386...33,000,562

G

complement factor D

CTD Direct Evidence: marker/mechanism

NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053

G

complement factor properdin

CTD Direct Evidence: marker/mechanism

NCBI chr X:1,162,014...1,167,576
Ensembl chr X:1,161,979...1,167,573

G

chondroitin sulfate synthase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:119,689,626...119,750,711
Ensembl chr 1:119,686,350...119,750,601

G

cell death-inducing DFFA-like effector a

CTD Direct Evidence: marker/mechanism

NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481

G

chemokine-like factor

CTD Direct Evidence: marker/mechanism

NCBI chr19:698,097...706,570
Ensembl chr19:698,033...706,570

G

C-type lectin domain family 4, member A1

CTD Direct Evidence: marker/mechanism

NCBI chr 4:156,173,894...156,186,009
Ensembl chr 4:156,173,894...156,186,008

G

C-type lectin domain family 4, member A3

CTD Direct Evidence: marker/mechanism

NCBI chr 4:156,214,030...156,224,818
Ensembl chr 4:156,214,718...156,224,817

G

C-type lectin domain family 4, member F

CTD Direct Evidence: marker/mechanism

NCBI chr 4:116,129,023...116,138,744
Ensembl chr 4:116,129,023...116,138,775

G

chloride intracellular channel 1

CTD Direct Evidence: marker/mechanism

NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712

G

chloride intracellular channel 2

CTD Direct Evidence: marker/mechanism

NCBI chr20:149,337...164,375
Ensembl chr20:148,907...164,355

G

cleavage factor polyribonucleotide kinase subunit 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:69,806,774...69,818,633
Ensembl chr 3:69,806,778...69,810,421

G

CKLF-like MARVEL transmembrane domain containing 3

CTD Direct Evidence: marker/mechanism

NCBI chr19:622,563...630,721
Ensembl chr19:604,458...629,790

G

carnosine dipeptidase 1

CTD Direct Evidence: marker/mechanism

NCBI chr18:77,984,886...78,030,837
Ensembl chr18:77,984,907...78,007,765

G

2',3'-cyclic nucleotide 3' phosphodiesterase

CTD Direct Evidence: marker/mechanism

NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720

G

canopy FGF signaling regulator 4

CTD Direct Evidence: marker/mechanism

NCBI chr12:17,064,642...17,070,755
Ensembl chr12:17,064,642...17,070,043

G

cannabinoid receptor 1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099

G

collagen type XII alpha 1 chain

CTD Direct Evidence: marker/mechanism

NCBI chr 8:80,547,592...80,665,665
Ensembl chr 8:80,547,593...80,665,686

G

collagen type I alpha 1 chain

treatment

IEP
ISO
IDA
IMP

protein:increased expression:liver
CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:liver (rat)

CTD
RGD

PMID:25380136 PMID:26435214 PMID:26739621 PMID:16009107 PMID:30346985 More...

RGD:1601595, RGD:151665755, RGD:8552768, RGD:8552710, RGD:5688339

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

G

collagen type I alpha 2 chain

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:25380136 PMID:7512265

NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867

G

collagen type III alpha 1 chain

CTD Direct Evidence: marker/mechanism

PMID:11788567 PMID:25380136

NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547

G

collagen type IV alpha 1 chain

CTD Direct Evidence: marker/mechanism

NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412

G

collagen type IV alpha 2 chain

CTD Direct Evidence: marker/mechanism

NCBI chr16:78,047,591...78,183,360
Ensembl chr16:78,047,602...78,183,839

G

collagen type V alpha 1 chain

CTD Direct Evidence: marker/mechanism

NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588

G

collagen type V alpha 2 chain

CTD Direct Evidence: marker/mechanism

NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154

G

collagen type VI alpha 1 chain

CTD Direct Evidence: marker/mechanism

NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597

G

collagen type VI alpha 2 chain

Protein:increased expression:liver
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:25380136 PMID:7791542

NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564

G

collectin sub-family member 12

CTD Direct Evidence: marker/mechanism

NCBI chr18:732,950...920,620
Ensembl chr18:732,950...920,618

G

coenzyme Q10A

CTD Direct Evidence: marker/mechanism

NCBI chr 7:792,089...798,392
Ensembl chr 7:792,089...800,161

G

coactosin-like F-actin binding protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr19:47,871,689...47,906,010
Ensembl chr19:47,871,694...47,911,689

G

carboxypeptidase Q

CTD Direct Evidence: marker/mechanism

NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546

G

carbamoyl-phosphate synthase 1

mRNA:decreased expression:liver
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:15650968 PMID:17539997

NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033

G

cAMP responsive element binding protein 1

associated with Chemical and Drug Induced Liver Injury

RGD

NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816

G

carnitine O-octanoyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109

G

C-reactive protein

protein:decreased expression:serum:

RGD

NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178

G

cartilage associated protein

CTD Direct Evidence: marker/mechanism

NCBI chr 8:114,047,929...114,067,636
Ensembl chr 8:114,047,933...114,067,631

G

cryptochrome circadian regulator 1

CTD Direct Evidence: marker/mechanism

NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091

G

crystallin, alpha B

CTD Direct Evidence: marker/mechanism

NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157

G

cysteine sulfinic acid decarboxylase

CTD Direct Evidence: marker/mechanism

NCBI chr 7:133,308,571...133,337,914
Ensembl chr 7:133,308,574...133,337,615

G

colony stimulating factor 1 receptor

CTD Direct Evidence: marker/mechanism

NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415

G

colony stimulating factor 3

CTD Direct Evidence: therapeutic

NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603

G

chondroitin sulfate N-acetylgalactosaminyltransferase 1

CTD Direct Evidence: marker/mechanism

NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319

G

cathepsin E

CTD Direct Evidence: marker/mechanism

NCBI chr13:43,091,954...43,114,509
Ensembl chr13:43,092,128...43,114,502

G

cathepsin S

CTD Direct Evidence: marker/mechanism

NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483

G

cathepsin Z

CTD Direct Evidence: marker/mechanism

NCBI chr 3:163,224,875...163,235,645
Ensembl chr 3:163,224,875...163,235,645

G

CTTNBP2 N-terminal like

CTD Direct Evidence: marker/mechanism

NCBI chr 2:192,507,963...192,554,548
Ensembl chr 2:192,507,963...192,541,101

G

CXADR, Ig-like cell adhesion molecule

CTD Direct Evidence: marker/mechanism

NCBI chr11:16,982,864...17,030,078
Ensembl chr11:16,982,860...17,030,046

G

C-X-C motif chemokine ligand 1

CTD Direct Evidence: marker/mechanism

NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215

G

C-X-C motif chemokine ligand 10

CTD Direct Evidence: marker/mechanism

NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975

G

C-X-C motif chemokine ligand 12

CTD Direct Evidence: marker/mechanism

NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168

G

C-X-C motif chemokine ligand 13

CTD Direct Evidence: marker/mechanism

NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933

G

C-X-C motif chemokine ligand 16

CTD Direct Evidence: marker/mechanism

NCBI chr10:55,166,721...55,171,316
Ensembl chr10:55,166,723...55,171,592

G

C-X-C motif chemokine ligand 3

CTD Direct Evidence: marker/mechanism

NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511

G

C-X-C motif chemokine ligand 9

CTD Direct Evidence: marker/mechanism

NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435

G

cytochrome b-245 alpha chain

CTD Direct Evidence: marker/mechanism

NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721

G

cytochrome b-245 beta chain

CTD Direct Evidence: marker/mechanism

NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586

G

cytoglobin

CTD Direct Evidence: therapeutic

NCBI chr10:101,877,675...101,887,442
Ensembl chr10:101,877,676...101,887,442

G

cytochrome P450, family 17, subfamily a, polypeptide 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573

G

cytochrome P450, family 1, subfamily a, polypeptide 2

CTD Direct Evidence: marker/mechanism

NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312

G

cytochrome P450, family 26, subfamily a, polypeptide 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204

G

cytochrome P450, family 2, subfamily a, polypeptide 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:82,263,833...82,289,487
Ensembl chr 1:82,263,833...82,289,487

G

cytochrome P450, subfamily 2, polypeptide 11

CTD Direct Evidence: marker/mechanism

NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066

G

cytochrome P450, family 2, subfamily d, polypeptide 4

CTD Direct Evidence: marker/mechanism

NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759

G

cytochrome P450, family 2, subfamily t, polypeptide 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:82,446,321...82,451,564
Ensembl chr 1:82,446,921...82,451,563

G

cytochrome P450, family 3, subfamily a, polypeptide 9

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422

G

cytochrome P450 family 7 subfamily A member 1

treatment

RGD

NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688

G

CYFIP related Rac1 interactor A

CTD Direct Evidence: marker/mechanism

NCBI chr 6:35,045,208...35,150,669
Ensembl chr 6:35,045,208...35,150,668

G

CYFIP related Rac1 interactor B

CTD Direct Evidence: marker/mechanism

NCBI chr 7:95,633,876...95,760,588
Ensembl chr 7:95,633,876...95,697,686

G

cysteine-rich transmembrane module containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr18:27,945,862...28,013,509
Ensembl chr18:27,951,653...28,013,510

G

dystroglycan 1

mRNA:increased expression:liver

RGD

NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325

G

D-amino-acid oxidase

CTD Direct Evidence: marker/mechanism

NCBI chr12:42,592,342...42,613,046
Ensembl chr12:42,592,343...42,612,741

G

dopamine beta-hydroxylase

mRNA:decreased expression:superior mesenteric artery (rat)

RGD

NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248

G

dysbindin domain containing 2

CTD Direct Evidence: marker/mechanism

NCBI chr 3:153,216,300...153,220,651
Ensembl chr 3:153,191,090...153,220,651

G

dicarbonyl and L-xylulose reductase

CTD Direct Evidence: marker/mechanism

NCBI chr10:106,006,404...106,008,293

G

dopa decarboxylase

mRNA:decreased expression:superior mesenteric artery (rat)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:25380136 PMID:18457899

NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208

G

DEP domain containing 7

CTD Direct Evidence: marker/mechanism

NCBI chr 3:91,099,111...91,121,152
Ensembl chr 3:91,099,835...91,121,124

G

dehydrogenase/reductase 3

CTD Direct Evidence: marker/mechanism

NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417

G

dehydrogenase/reductase 7

CTD Direct Evidence: marker/mechanism

NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892

G

dehydrogenase E1 and transketolase domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr17:72,355,201...72,406,725
Ensembl chr17:72,355,201...72,406,723

G

iodothyronine deiodinase 1

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970

G

divergent protein kinase domain 2A

CTD Direct Evidence: marker/mechanism

NCBI chr 8:95,070,695...95,089,815
Ensembl chr 8:95,030,279...95,089,815

G

dedicator of cytokinesis 10

CTD Direct Evidence: marker/mechanism

NCBI chr 9:81,843,599...82,101,540
Ensembl chr 9:81,843,604...82,101,525

G

dedicator of cytokinesis 7

CTD Direct Evidence: marker/mechanism

NCBI chr 5:113,599,371...113,782,871
Ensembl chr 5:113,600,198...113,782,813

G

dipeptidylpeptidase 7

CTD Direct Evidence: marker/mechanism

NCBI chr 3:8,165,091...8,169,343
Ensembl chr 3:8,165,091...8,169,355

G

dihydropyrimidinase

CTD Direct Evidence: marker/mechanism

NCBI chr 7:70,822,648...70,929,255
Ensembl chr 7:70,835,789...70,929,231

G

DNA-damage regulated autophagy modulator 1

CTD Direct Evidence: marker/mechanism

NCBI chr 7:22,742,794...22,776,888
Ensembl chr 7:22,742,849...22,776,765

G

dihydrouridine synthase 1-like

CTD Direct Evidence: marker/mechanism

NCBI chr10:106,055,519...106,062,656
Ensembl chr10:106,055,519...106,062,781

G

dual specificity phosphatase 16

CTD Direct Evidence: marker/mechanism

NCBI chr 4:167,546,780...167,630,173
Ensembl chr 4:167,548,155...167,629,980

G

dual specificity phosphatase 6

CTD Direct Evidence: marker/mechanism

NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185

G

dysferlin

CTD Direct Evidence: marker/mechanism

NCBI chr 4:116,490,877...116,690,709
Ensembl chr 4:116,490,616...116,690,709

G

endothelin converting enzyme 1

protein:increased expression:liver

RGD

NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371

G

epithelial cell transforming 2

CTD Direct Evidence: marker/mechanism

NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911

G

endothelin 1

CTD Direct Evidence: therapeutic

NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885

G

EEIG family member 2

CTD Direct Evidence: marker/mechanism

NCBI chr 2:196,608,499...196,663,371
Ensembl chr 2:196,608,499...196,663,371

G

epidermal growth factor

CTD Direct Evidence: marker/mechanism

NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064

G

eukaryotic translation initiation factor 4E family member 3

CTD Direct Evidence: marker/mechanism

NCBI chr 4:132,258,502...132,301,808
Ensembl chr 4:132,258,502...132,301,808

G

ELOVL fatty acid elongase 5

CTD Direct Evidence: marker/mechanism

NCBI chr 8:78,790,846...78,857,307
Ensembl chr 8:78,790,846...78,857,284

G

embigin

CTD Direct Evidence: marker/mechanism

NCBI chr 2:49,070,509...49,125,042
Ensembl chr 2:49,069,087...49,125,050

G

epithelial membrane protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr 4:168,212,901...168,233,039
Ensembl chr 4:168,212,861...168,232,904

G

ectodermal-neural cortex 1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713

G

glutamyl aminopeptidase

CTD Direct Evidence: marker/mechanism

NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947

G

ectonucleotide pyrophosphatase/phosphodiesterase 2

treatment

protein:increased activity:serum:
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:17072980 PMID:17850827 PMID:20957682

RGD:9685426, RGD:9685427

NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827

G

ectonucleoside triphosphate diphosphohydrolase 2

RGD

NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866

G

erythrocyte membrane protein band 4.1-like 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:19,863,010...20,037,795
Ensembl chr 1:19,863,009...20,037,721

G

epithelial cell adhesion molecule

CTD Direct Evidence: marker/mechanism

NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127

G

endoplasmic reticulum aminopeptidase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:3,931,817...3,970,735
Ensembl chr 2:3,931,904...3,972,447

G

endoplasmic reticulum to nucleus signaling 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029

G

exostosin-like glycosyltransferase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 5:146,573,911...146,589,115
Ensembl chr 5:146,573,912...146,589,115

G

ezrin

CTD Direct Evidence: marker/mechanism

NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505

G

coagulation factor II (thrombin) receptor

CTD Direct Evidence: marker/mechanism

NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870

G

coagulation factor V

treatment

RGD

NCBI chr13:76,513,509...76,583,106
Ensembl chr13:76,513,255...76,582,317

G

fatty acid binding protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089

G

fatty acid binding protein 7

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880

G

fumarylacetoacetate hydrolase domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:13,873,539...13,874,978
Ensembl chr10:13,873,527...13,875,012

G

family with sequence similarity 167, member B

CTD Direct Evidence: marker/mechanism

NCBI chr 5:141,920,695...141,922,342
Ensembl chr 5:141,920,695...141,922,340

G

family with sequence similarity 43, member A

CTD Direct Evidence: marker/mechanism

NCBI chr11:70,128,253...70,131,401
Ensembl chr11:70,128,253...70,131,401

G

family with sequence similarity 89, member A

CTD Direct Evidence: marker/mechanism

NCBI chr19:52,710,002...52,722,630
Ensembl chr19:52,710,019...52,722,631

G

Fas cell surface death receptor

mRNA, protein:increased expression:liver
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:30737368 PMID:17105443

NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591

G

FAT atypical cadherin 1

CTD Direct Evidence: marker/mechanism

NCBI chr16:47,177,253...47,296,261
Ensembl chr16:47,177,248...47,296,107

G

fibrillin 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889

G

f-box protein 9

CTD Direct Evidence: marker/mechanism

NCBI chr 8:78,958,482...78,984,015
Ensembl chr 8:78,958,483...78,983,949

G

Fc epsilon receptor Ig

CTD Direct Evidence: marker/mechanism

NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443

G

Fc gamma receptor 1A

CTD Direct Evidence: marker/mechanism

NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994

G

Fc gamma receptor 3A

CTD Direct Evidence: marker/mechanism

NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921

G

ficolin B

CTD Direct Evidence: marker/mechanism

NCBI chr 3:11,393,713...11,402,198
Ensembl chr 3:11,393,739...11,402,151

G

fibroblast growth factor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221

G

Fibroblast growth factor receptor 1

treatment

RGD

NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350

G

fibrinogen gamma chain

mRNA:increased expression

RGD

NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322

G

fibrinogen-like 2

CTD Direct Evidence: marker/mechanism

NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207

G

FGR proto-oncogene, Src family tyrosine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326

G

four and a half LIM domains 1

CTD Direct Evidence: marker/mechanism

NCBI chr X:134,555,399...134,614,930
Ensembl chr X:134,555,479...134,614,928

G

four and a half LIM domains 2

CTD Direct Evidence: marker/mechanism

NCBI chr 9:45,388,979...45,462,421
Ensembl chr 9:45,388,981...45,431,192

G

FKBP prolyl isomerase 1A

CTD Direct Evidence: marker/mechanism

NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743

G

Fli-1 proto-oncogene, ETS transcription factor

CTD Direct Evidence: marker/mechanism

NCBI chr 8:30,831,422...30,950,468
Ensembl chr 8:30,832,753...30,950,433

G

filamin A

CTD Direct Evidence: marker/mechanism

NCBI chr X:152,007,758...152,034,266
Ensembl chr X:152,007,758...152,031,052

G

formin-like 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:88,115,876...88,143,342
Ensembl chr10:88,116,009...88,143,357

G

formin-like 2

CTD Direct Evidence: marker/mechanism

NCBI chr 3:37,348,791...37,624,746
Ensembl chr 3:37,348,574...37,624,754

G

flavin containing dimethylaniline monoxygenase 1

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647

G

fibronectin 1

treatment

mRNA:increased expression:liver:
mRNA:altered expression:liver (rat)

RGD

PMID:19914391 PMID:15980055

RGD:4140452, RGD:1625201

NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678

G

folate receptor beta

CTD Direct Evidence: marker/mechanism

NCBI chr 1:156,200,044...156,218,380
Ensembl chr 1:156,200,060...156,205,724

G

Fos proto-oncogene, AP-1 transcription factor subunit

CTD Direct Evidence: marker/mechanism

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

forkhead box A2

CTD Direct Evidence: marker/mechanism

NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326

G

forkhead box O1

associated with Schistosomiasis Japonica; mRNA:decreased expression:liver (rat)

RGD

NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790

G

FRY microtubule binding protein

CTD Direct Evidence: marker/mechanism

NCBI chr12:4,493,890...4,887,118
Ensembl chr12:4,493,891...4,799,116

G

follistatin-like 1

CTD Direct Evidence: marker/mechanism

NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677

G

formimidoyltransferase cyclodeaminase

CTD Direct Evidence: marker/mechanism

NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735

G

FXYD domain-containing ion transport regulator 2

CTD Direct Evidence: marker/mechanism

NCBI chr 8:45,712,901...45,720,032
Ensembl chr 8:45,712,903...45,720,203

G

FXYD domain-containing ion transport regulator 5

CTD Direct Evidence: marker/mechanism

NCBI chr 1:86,267,937...86,277,329
Ensembl chr 1:86,267,406...86,277,519

G

FXYD domain-containing ion transport regulator 6

CTD Direct Evidence: marker/mechanism

NCBI chr 8:45,679,054...45,705,958
Ensembl chr 8:45,678,885...45,705,958

G

FYN proto-oncogene, Src family tyrosine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911

G

frizzled class receptor 8

CTD Direct Evidence: marker/mechanism

NCBI chr17:57,312,924...57,320,551
Ensembl chr17:57,314,450...57,320,650

G

G0/G1switch 2

CTD Direct Evidence: marker/mechanism

NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451

G

glucose-6-phosphatase catalytic subunit 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804

G

GRB2-associated binding protein 1

protein:increased tyrosine phosphorylation: :

RGD

NCBI chr19:27,131,262...27,239,236
Ensembl chr19:27,131,262...27,239,236

G

galactosylceramidase

CTD Direct Evidence: marker/mechanism

NCBI chr 6:117,452,888...117,522,281
Ensembl chr 6:117,452,895...117,515,830

G

golgi associated kinase 1B

CTD Direct Evidence: marker/mechanism

NCBI chr 2:165,047,689...165,112,479
Ensembl chr 2:165,047,684...165,112,477

G

guanylate binding protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571

G

guanylate binding protein 4

CTD Direct Evidence: marker/mechanism

NCBI chr 2:231,304,910...231,318,883
Ensembl chr 2:231,305,244...231,318,879

G

GC, vitamin D binding protein

CTD Direct Evidence: marker/mechanism

NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567

G

glycine C-acetyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chr 7:110,595,126...110,601,474
Ensembl chr 7:110,595,091...110,601,473

G

GTP cyclohydrolase I feedback regulator

CTD Direct Evidence: marker/mechanism

NCBI chr 3:106,158,046...106,162,080
Ensembl chr 3:106,159,394...106,162,080

G

glucokinase

CTD Direct Evidence: marker/mechanism

NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995

G

glucosaminyl (N-acetyl) transferase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:214,718,344...214,755,735
Ensembl chr 1:214,718,293...214,758,776

G

guided entry of tail-anchored proteins factor 1

CTD Direct Evidence: marker/mechanism

NCBI chr11:35,438,555...35,460,156
Ensembl chr11:35,445,815...35,459,973

G

glial fibrillary acidic protein

associated with Schistosomiasis Japonica; mRNA:decreased expression:liver (rat)

RGD

NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589

G

GDNF family receptor alpha 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:257,315,682...257,552,004
Ensembl chr 1:257,321,742...257,551,473

G

gamma-glutamyl hydrolase

CTD Direct Evidence: marker/mechanism

NCBI chr 5:33,529,880...33,552,790
Ensembl chr 5:33,529,880...33,552,787

G

glycoprotein alpha-galactosyltransferase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:18,732,985...18,824,916
Ensembl chr 3:18,732,991...18,809,908

G

growth hormone 1

CTD Direct Evidence: therapeutic

NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078

G

growth hormone receptor

mRNA, protein:decreased expression:liver
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:17072980 PMID:25380136 PMID:12679928

NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735

G

gap junction protein, alpha 1

CTD Direct Evidence: marker/mechanism

NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582

G

gap junction protein, alpha 4

CTD Direct Evidence: marker/mechanism

NCBI chr 5:139,633,324...139,635,857
Ensembl chr 5:139,633,287...139,635,925

G

glycerol kinase

CTD Direct Evidence: marker/mechanism

NCBI chr X:50,162,089...50,238,707
Ensembl chr X:50,163,123...50,238,631

G

GLI pathogenesis-related 1

CTD Direct Evidence: marker/mechanism

NCBI chr 7:47,487,342...47,498,974
Ensembl chr 7:47,487,345...47,498,429

G

glutaminase

CTD Direct Evidence: marker/mechanism

NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900

G

glutaminase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 7:617,252...633,424
Ensembl chr 7:617,288...633,426

G

glycosyltransferase 8 domain containing 1

CTD Direct Evidence: marker/mechanism

NCBI chr16:6,192,269...6,207,227
Ensembl chr16:6,192,300...6,207,229

G

glia maturation factor, gamma

CTD Direct Evidence: marker/mechanism

NCBI chr 1:83,728,797...83,739,189
Ensembl chr 1:83,728,776...83,739,183

G

G protein subunit alpha 14

CTD Direct Evidence: marker/mechanism

NCBI chr 1:213,714,993...213,900,083
Ensembl chr 1:213,716,020...213,897,423

G

G protein subunit alpha i2

CTD Direct Evidence: marker/mechanism

NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979

G

G protein subunit gamma transducin 2

CTD Direct Evidence: marker/mechanism

NCBI chr10:80,776,003...80,784,235

G

glucosamine-6-phosphate deaminase 1

CTD Direct Evidence: marker/mechanism

NCBI chr18:30,165,435...30,177,462
Ensembl chr18:30,165,427...30,177,486

G

glutamic-oxaloacetic transaminase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633

G

glycerol-3-phosphate acyltransferase, mitochondrial

CTD Direct Evidence: marker/mechanism

NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639

G

glycoprotein nmb

CTD Direct Evidence: marker/mechanism

NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367

G

G protein-coupled receptor 68

CTD Direct Evidence: marker/mechanism

NCBI chr 6:120,135,620...120,166,089
Ensembl chr 6:120,135,436...120,166,089

G

glutamic--pyruvic transaminase

treatment

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:17072980 PMID:22706148

NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494

G

glutathione peroxidase 8

CTD Direct Evidence: marker/mechanism

NCBI chr 2:44,676,448...44,680,042
Ensembl chr 2:44,676,454...44,680,195

G

G protein-coupled receptor kinase 2

protein:increased expression:aorta

RGD

NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582

G

granulin precursor

CTD Direct Evidence: marker/mechanism

NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775

G

gelsolin

mRNA, protein:increased expression
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:25380136 PMID:14574581

NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402

G

glutathione S-transferase alpha 2

CTD Direct Evidence: marker/mechanism

NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798

G

glutathione S-transferase alpha 4

treatment

RGD

NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182

G

glutathione S-transferase mu 1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411

G

glutathione S-transferase pi 3

CTD Direct Evidence: marker/mechanism

NCBI chr 1:201,355,682...201,358,216
Ensembl chr 1:201,355,682...201,358,330

G

GULP PTB domain containing engulfment adaptor 1

CTD Direct Evidence: marker/mechanism

NCBI chr 9:46,622,699...46,899,005
Ensembl chr 9:46,622,669...46,899,005

G

granzyme A

CTD Direct Evidence: marker/mechanism

NCBI chr 2:44,740,569...44,752,502
Ensembl chr 2:44,740,569...44,752,493

G

hydroxyacyl glutathione hydrolase

CTD Direct Evidence: marker/mechanism

NCBI chr10:13,874,883...13,889,527
Ensembl chr10:13,875,241...13,889,504

G

histidine ammonia lyase

CTD Direct Evidence: marker/mechanism

NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701

G

hydroxyacid oxidase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:121,757,400...121,828,721
Ensembl chr 3:121,771,836...121,828,721

G

hydroxyacid oxidase 2

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425

G

HCK proto-oncogene, Src family tyrosine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693

G

helicase, lymphoid specific

CTD Direct Evidence: marker/mechanism

NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844

G

HEXIM P-TEFb complex subunit 1

CTD Direct Evidence: marker/mechanism

NCBI chr10:88,062,808...88,064,920
Ensembl chr10:88,062,803...88,066,189

G

hepatocyte growth factor

CTD Direct Evidence: therapeutic

PMID:10677585 PMID:12918455 PMID:15793283 PMID:16465399 PMID:16627068 More...

NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409

G

huntingtin interacting protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr12:21,133,364...21,267,796
Ensembl chr12:21,133,406...21,267,725

G

hemojuvelin BMP co-receptor

CTD Direct Evidence: marker/mechanism

NCBI chr 2:184,065,944...184,069,851
Ensembl chr 2:184,065,970...184,069,850

G

3-hydroxy-3-methylglutaryl-CoA reductase

CTD Direct Evidence: marker/mechanism

NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703

G

heme oxygenase 1

CTD Direct Evidence: marker/mechanism|therapeutic

CTD
RGD

PMID:16025519 PMID:16610050 PMID:21163135 PMID:25380136 PMID:19554654

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

HOP homeobox

CTD Direct Evidence: marker/mechanism

NCBI chr14:31,055,912...31,082,909
Ensembl chr14:31,075,148...31,082,909

G

homeobox A3

CTD Direct Evidence: marker/mechanism

NCBI chr 4:81,269,243...81,313,218
Ensembl chr 4:81,269,243...81,313,218

G

haptoglobin

protein:increased expression:serum
protein:decreased expression:serum

RGD

PMID:16968543 PMID:21806828

RGD:1626367, RGD:9491781

NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523

G

hippocalcin-like 1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:40,478,206...40,584,721
Ensembl chr 6:40,478,208...40,584,687

G

hematopoietic prostaglandin D synthase

CTD Direct Evidence: marker/mechanism

NCBI chr 4:94,368,426...94,397,931
Ensembl chr 4:94,373,342...94,397,883

G

heparanase

CTD Direct Evidence: marker/mechanism

PMID:15095483 PMID:18458672

NCBI chr14:8,896,593...8,937,011
Ensembl chr14:8,896,593...8,937,010

G

hydroxysteroid (17-beta) dehydrogenase 2

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202

G

hydroxysteroid (17-beta) dehydrogenase 6

CTD Direct Evidence: marker/mechanism

NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425

G

5-hydroxytryptamine receptor 2B

protein:increased expression:liver (rat)

RGD

NCBI chr 9:86,735,793...86,756,638
Ensembl chr 9:86,742,102...86,755,108

G

hydroxylysine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr 8:55,315,919...55,339,720
Ensembl chr 8:55,315,969...55,337,339

G

intercellular adhesion molecule 2

CTD Direct Evidence: marker/mechanism

NCBI chr10:91,308,608...91,319,536
Ensembl chr10:91,308,538...91,315,293

G

inhibitor of DNA binding 2

CTD Direct Evidence: therapeutic

NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400

G

inhibitor of DNA binding 4

CTD Direct Evidence: marker/mechanism

NCBI chr17:16,389,387...16,391,956
Ensembl chr17:16,389,387...16,392,470

G

indoleamine 2,3-dioxygenase 1

severity

protein:increased expression:serum (mouse)

RGD

PMID:28465467 PMID:28465467

RGD:39939037, RGD:39939037

NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730

G

alpha-L-iduronidase

protein:increased expression:liver

RGD

NCBI chr14:1,031,588...1,059,494
Ensembl chr14:1,032,171...1,046,522

G

interferon-induced protein 35

CTD Direct Evidence: marker/mechanism

NCBI chr10:86,381,023...86,389,279
Ensembl chr10:86,381,010...86,389,952

G

interferon induced transmembrane protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169

G

interferon, alpha 1

CTD Direct Evidence: therapeutic

PMID:12898905 PMID:14512876 PMID:16027843

NCBI chr 5:103,097,356...103,097,925
Ensembl chr 5:103,097,356...103,097,925

G

interferon gamma

CTD Direct Evidence: therapeutic
protein:increased expression:serum (mouse)

CTD
RGD

PMID:12389079 PMID:15996030 PMID:16953842 PMID:17347453 PMID:28465467

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

interferon gamma receptor 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785

G

interferon-related developmental regulator 1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990

G

insulin-like growth factor 1

treatment

CTD Direct Evidence: therapeutic
protein:increased expression:liver:

CTD
RGD

PMID:15591519 PMID:15745444 PMID:16434425 PMID:20198635 PMID:12800242

RGD:2317647, RGD:12904923, RGD:10045984

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

G

insulin-like growth factor 1 receptor

protein:increased expression:liver:

RGD

NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777

G

insulin-like growth factor 2 mRNA binding protein 3

CTD Direct Evidence: marker/mechanism

NCBI chr 4:78,060,494...78,195,007
Ensembl chr 4:78,060,494...78,194,865

G

insulin-like growth factor 2 receptor

CTD Direct Evidence: marker/mechanism

NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501

G

insulin-like growth factor binding protein, acid labile subunit

CTD Direct Evidence: marker/mechanism

NCBI chr10:13,897,468...13,903,920
Ensembl chr10:13,898,395...13,902,677

G

insulin-like growth factor binding protein 1

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482

G

insulin-like growth factor binding protein 2

CTD Direct Evidence: marker/mechanism

PMID:17072980 PMID:25380136

NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937

G

insulin-like growth factor binding protein 3

CTD Direct Evidence: marker/mechanism

NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083

G

insulin-like growth factor binding protein 7

treatment

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:25380136 PMID:25691930

NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314

G

immunoglobulin superfamily, member 6

CTD Direct Evidence: marker/mechanism

NCBI chr 1:175,610,167...175,620,662
Ensembl chr 1:175,610,167...175,620,722

G

inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

CTD Direct Evidence: marker/mechanism

NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499

G

interleukin 10

treatment

CTD Direct Evidence: therapeutic

CTD
RGD

PMID:12632514 PMID:15362042 PMID:16097045 PMID:16126171 PMID:16539848 More...

RGD:7364982, RGD:11049490

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

G

interleukin 17A

treatment

protein:increased expression:liver, serum (mouse)

RGD

PMID:28465467 PMID:30346985

RGD:39939037, RGD:151665755

NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889

G

interleukin 17 receptor A

treatment

RGD

NCBI chr 4:153,667,534...153,690,174
Ensembl chr 4:153,667,534...153,690,174

G

interleukin 17 receptor C

treatment

RGD

NCBI chr 4:146,618,321...146,631,444
Ensembl chr 4:146,619,004...146,631,442

G

interleukin 18

CTD Direct Evidence: marker/mechanism

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

G

interleukin 18 binding protein

CTD Direct Evidence: marker/mechanism

NCBI chr 1:156,372,923...156,374,963
Ensembl chr 1:156,372,883...156,374,963

G

interleukin 1 beta

treatment

CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:16085334 PMID:24383550

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 2

treatment

RGD

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

interleukin 2 receptor subunit beta

CTD Direct Evidence: marker/mechanism

NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054

G

interleukin 2 receptor subunit gamma

CTD Direct Evidence: marker/mechanism

NCBI chr X:66,395,330...66,399,026
Ensembl chr X:66,392,542...66,399,823

G

interleukin 33

CTD Direct Evidence: marker/mechanism

NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373

G

interleukin 4

protein:decreased expression:serum (mouse)

RGD