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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:ST Elevation Myocardial Infarction
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Accession:DOID:9000740 term browser browse the term
Definition:A clinical syndrome defined by MYOCARDIAL ISCHEMIA symptoms; persistent elevation in the ST segments of the ELECTROCARDIOGRAM; and release of BIOMARKERS of myocardial NECROSIS (e.g., elevated TROPONIN levels). ST segment elevation in the ECG is often used in determining the treatment protocol (see also NON-ST ELEVATION MYOCARDIAL INFARCTION).
Synonyms:exact_synonym: ST Elevated Myocardial Infarction;   ST Segment Elevation Myocardial Infarction;   STEMI
 primary_id: MESH:D000072657;   RDO:0016116
 xref: EFO:0008585


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ST Elevation Myocardial Infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A treatment ISO DNA:SNPs: :rs1045642,rs7779562(human) RGD PMID:25217066 RGD:14700903 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Atp5mc2 ATP synthase membrane subunit c locus 2 severity ISO RGD PMID:27441480 RGD:14696800 NCBI chr 7:135,669,847...135,680,839
Ensembl chr 7:135,669,848...135,678,231 		JBrowse link
G Ccn1 cellular communication network factor 1 sexual_dimorphism ISO protein:increased expression:blood serum (human) RGD PMID:34597881 RGD:329845519 NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883 		JBrowse link
G Lgals3 galectin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29769800 NCBI chr15:23,099,795...23,111,731
Ensembl chr15:23,086,841...23,111,737 		JBrowse link
G Mir208a microRNA 208a severity IEP miRNA:increased expression:blood RGD PMID:32458401 RGD:213230165 NCBI chr15:32,395,552...32,395,634 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19167
    disease of anatomical entity 18473
      cardiovascular system disease 5558
        heart disease 3483
          Myocardial Ischemia 951
            myocardial infarction 447
              ST Elevation Myocardial Infarction 5
Path 2
Term Annotations click to browse term
  disease 19167
    disease of anatomical entity 18473
      cardiovascular system disease 5558
        vascular disease 4039
          ischemia 1506
            Myocardial Ischemia 951
              Coronary Disease 629
                coronary artery disease 603
                  myocardial infarction 447
                    ST Elevation Myocardial Infarction 5
paths to the root