Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:lupus erythematosus
go back to main search page
Accession:DOID:8857 term browser browse the term
Definition:An autoimmune disease that is characterized by a constellation of findings that include elevated antibodies to nuclear antigens, antiphospholipids, low complement levels, ulcers, non-scarring alopecia, renal or neurologic damage, and low white blood cell and platelet counts, has_symptom rashes, fatigue, arthritis, hair loss, seizures, and symptoms related to affected organs. (DO)
Synonyms:exact_synonym: lupus
 xref: ICD10CM:L93;   ICD9CM:695.4;   NCI:C27153
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
lupus erythematosus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD1D CD1d molecule ameliorates ISO RGD PMID:14561706 RGD:127345108 NCBI chr 1:158,178,030...158,186,427
Ensembl chr 1:158,178,030...158,186,427 		JBrowse link
C1q Deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QA complement C1q A chain IAGP ClinVar Annotator: match by term: C1Q deficiency ClinVar PMID:7594474 PMID:8840296 PMID:9225968 PMID:9590289 PMID:21654842 More... NCBI chr 1:22,636,463...22,639,678
Ensembl chr 1:22,635,077...22,639,678 		JBrowse link
G C1QB complement C1q B chain IAGP ClinVar Annotator: match by term: C1Q deficiency ClinVar PMID:17513176 PMID:21654842 PMID:25741868 PMID:28492532 NCBI chr 1:22,653,236...22,661,637
Ensembl chr 1:22,652,762...22,661,637 		JBrowse link
G C1QC complement C1q C chain IAGP ClinVar Annotator: match by term: C1Q deficiency ClinVar PMID:7029321 PMID:7900940 PMID:8630118 PMID:20635792 PMID:21654842 More... NCBI chr 1:22,643,633...22,648,108
Ensembl chr 1:22,643,014...22,648,110 		JBrowse link
C1q Deficiency 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QA complement C1q A chain IAGP ClinVar Annotator: match by term: C1QA-related condition
ClinVar Annotator: match by term: C1Q deficiency 1 		OMIM
ClinVar		 PMID:25741868 PMID:28492532 NCBI chr 1:22,636,463...22,639,678
Ensembl chr 1:22,635,077...22,639,678 		JBrowse link
C1q Deficiency 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QB complement C1q B chain IAGP ClinVar Annotator: match by term: C1Q deficiency 2
ClinVar Annotator: match by term: C1Q deficiency 2 | ClinVar Annotator: match by term: C1QB-related condition 		OMIM
ClinVar		 PMID:2894352 PMID:24160257 PMID:25741868 PMID:28492532 NCBI chr 1:22,653,236...22,661,637
Ensembl chr 1:22,652,762...22,661,637 		JBrowse link
C1q Deficiency 3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QC complement C1q C chain IAGP ClinVar Annotator: match by term: C1QC-related condition
ClinVar Annotator: match by term: C1Q deficiency 3 		OMIM
ClinVar		 PMID:7029321 PMID:8630118 PMID:24157463 PMID:28492532 NCBI chr 1:22,643,633...22,648,108
Ensembl chr 1:22,643,014...22,648,110 		JBrowse link
Chilblain lupus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATRIP ATR interacting protein IAGP ClinVar Annotator: match by term: Chilblain lupus ClinVar PMID:16960810 PMID:17357087 PMID:17440703 PMID:18805785 PMID:20799324 More... NCBI chr 3:48,446,779...48,467,645
Ensembl chr 3:48,446,710...48,467,645 		JBrowse link
G ATRIP ATR interacting protein IAGP ClinVar Annotator: match by term: Chilblain lupus ClinVar PMID:16960810 PMID:17357087 PMID:17440703 PMID:18805785 PMID:20799324 More... NCBI chr 3:48,446,737...48,467,645
Ensembl chr 3:48,446,710...48,467,645 		JBrowse link
G TREX1 three prime repair exonuclease 1 IAGP ClinVar Annotator: match by term: Chilblain lupus ClinVar PMID:16960810 PMID:17357087 PMID:17440703 PMID:18805785 PMID:20799324 More... NCBI chr 3:48,465,830...48,467,645
Ensembl chr 3:48,465,811...48,467,645 		JBrowse link
Chilblain Lupus 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATRIP ATR interacting protein IAGP ClinVar Annotator: match by term: Chilblain lupus 1 ClinVar PMID:16845398 PMID:17293595 PMID:17357087 PMID:17660818 PMID:17660820 More... NCBI chr 3:48,446,779...48,467,645
Ensembl chr 3:48,446,710...48,467,645 		JBrowse link
G ATRIP ATR interacting protein IAGP ClinVar Annotator: match by term: Chilblain lupus 1 ClinVar PMID:16845398 PMID:17293595 PMID:17357087 PMID:17660818 PMID:17660820 More... NCBI chr 3:48,446,737...48,467,645
Ensembl chr 3:48,446,710...48,467,645 		JBrowse link
G SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27566796 NCBI chr20:36,889,773...36,951,708
Ensembl chr20:36,890,229...36,951,893 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27566796 NCBI chr 5:139,475,533...139,482,758
Ensembl chr 5:139,475,533...139,482,935 		JBrowse link
G TREX1 three prime repair exonuclease 1 EXP
IAGP 		CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Chilblain lupus 1 		CTD
OMIM
ClinVar		 PMID:16845398 PMID:17293595 PMID:17357087 PMID:17660818 PMID:17660820 More... NCBI chr 3:48,465,830...48,467,645
Ensembl chr 3:48,465,811...48,467,645 		JBrowse link
Chilblain Lupus 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC130065805 ATAC-STARR-seq lymphoblastoid silent region 12883 IAGP ClinVar Annotator: match by term: Chilblain lupus 2 ClinVar PMID:25741868 NCBI chr20:36,951,203...36,951,422 JBrowse link
G SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 IAGP ClinVar Annotator: match by term: SAMHD1-related condition
ClinVar Annotator: match by term: Chilblain lupus 2 | ClinVar Annotator: match by term: SAMHD1-related condition 		OMIM
ClinVar		 PMID:19525956 PMID:20653736 PMID:21204240 PMID:21402907 PMID:22461318 More... NCBI chr20:36,889,773...36,951,708
Ensembl chr20:36,890,229...36,951,893 		JBrowse link
G TLDC2 TBC/LysM-associated domain containing 2 IAGP ClinVar Annotator: match by term: Chilblain lupus 2
ClinVar Annotator: match by term: SAMHD1-related condition 		ClinVar PMID:25741868 PMID:28492532 NCBI chr20:36,876,121...36,894,235
Ensembl chr20:36,876,121...36,894,235 		JBrowse link
cutaneous lupus erythematosus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCR3 C-C motif chemokine receptor 3 IEP RGD PMID:21844117 RGD:6892918 NCBI chr 3:46,210,696...46,266,706
Ensembl chr 3:46,130,890...46,266,706 		JBrowse link
G CD40 CD40 molecule IEP RGD PMID:18050371 RGD:8547765 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CD40LG CD40 ligand IEP RGD PMID:18050371 RGD:8547765 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390 		JBrowse link
G CSF1 colony stimulating factor 1 ISO RGD PMID:18981160 RGD:7257572 NCBI chr 1:109,910,506...109,930,992
Ensembl chr 1:109,910,242...109,930,992 		JBrowse link
G IL17A interleukin 17A IEP protein:increased expression:epidermis (human) RGD PMID:20493423 RGD:8698667 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G TREX1 three prime repair exonuclease 1 ISS MouseDO NCBI chr 3:48,465,830...48,467,645
Ensembl chr 3:48,465,811...48,467,645 		JBrowse link
Discoid Lupus Erythematosus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 IDA RGD PMID:20701627 RGD:7421565 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,629 		JBrowse link
G CD40 CD40 molecule IEP RGD PMID:18050371 RGD:8547765 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CD40LG CD40 ligand IEP RGD PMID:18050371 RGD:8547765 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390 		JBrowse link
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 susceptibility IAGP DNA:polymorphism: :HLA-DQA1*0102 RGD PMID:7883595 RGD:8547567 NCBI chr 6:32,637,406...32,655,272
Ensembl chr 6:32,628,179...32,647,062 		JBrowse link
G IL17A interleukin 17A IEP protein:increased expression:epidermis (human) RGD PMID:20493423 RGD:8698667 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G NAT2 N-acetyltransferase 2 treatment IAGP DNA:polymorphisms: : RGD PMID:9170150 RGD:8552671 NCBI chr 8:18,386,301...18,401,218
Ensembl chr 8:18,391,282...18,401,218 		JBrowse link
G OGG1 8-oxoguanine DNA glycosylase EXP CTD Direct Evidence: marker/mechanism CTD PMID:33072095 NCBI chr 3:9,749,952...9,783,108
Ensembl chr 3:9,749,944...9,788,219 		JBrowse link
G TRAF3IP2 TRAF3 interacting protein 2 IAGP ClinVar Annotator: match by term: Discoid lupus erythematosus ClinVar PMID:25741868 NCBI chr 6:111,555,381...111,605,878
Ensembl chr 6:111,555,381...111,606,906 		JBrowse link
G TRAF3IP2-AS1 TRAF3IP2 antisense RNA 1 IAGP ClinVar Annotator: match by term: Discoid lupus erythematosus ClinVar PMID:25741868 NCBI chr 6:111,483,472...111,602,295
Ensembl chr 6:111,483,389...111,598,784 		JBrowse link
lupus nephritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor IAGP DNA:polymorphisms:promoter, intron:g.-429T>C rs1800625, g.-374T>A rs1800624, g.2184A>G rs3134940 (human) RGD PMID:22513366 RGD:6767309 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322 		JBrowse link
G APOC3 apolipoprotein C3 IEP protein:increased expression:serum RGD PMID:17957542 RGD:7207211 NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072 		JBrowse link
G C3 complement C3 IEP
EXP 		protein:decreased expression:serum
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:31182691 PMID:21888025 RGD:7175544 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 severity
susceptibility 		IEP
IAGP 		protein:increased expression:urine (human)
DNA:snp:promoter:g.-2518A>G (human) 		RGD PMID:8558841 PMID:15188361 RGD:8549732, RGD:11528534 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL3 C-C motif chemokine ligand 3 ISO RGD PMID:18187931 RGD:7241814 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169 		JBrowse link
G CCR1 C-C motif chemokine receptor 1 disease_progression ISO RGD PMID:15153561 RGD:5688164 NCBI chr 3:46,201,711...46,208,313
Ensembl chr 3:46,201,711...46,208,313 		JBrowse link
G CD40 CD40 molecule treatment ISO RGD PMID:23799000 PMID:18566369 PMID:19265127 RGD:7248418, RGD:7248429, RGD:7248425 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CD40LG CD40 ligand treatment IEP
ISO
IMP
IDA 		protein:increased expression:serum RGD PMID:20726330 PMID:11751940 PMID:12632425 PMID:13130474 PMID:15693003 RGD:7248426, RGD:7248714, RGD:7248710, RGD:7248600, RGD:7248439 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390 		JBrowse link
G CFB complement factor B ISO
IEP 		RGD PMID:10623824 PMID:3183062 PMID:21893562 RGD:7242736, RGD:7242763, RGD:7242755 NCBI chr 6:31,946,095...31,952,084
Ensembl chr 6:31,945,650...31,952,086 		JBrowse link
G CFH complement factor H IAGP RGD PMID:22171659 RGD:5684551 NCBI chr 1:196,652,043...196,747,504
Ensembl chr 1:196,651,754...196,752,476 		JBrowse link
G CLU clusterin ISO mRNA:increased expression: epithelial cell of renal tubule RGD PMID:9546356 RGD:8890679 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700 		JBrowse link
G COL1A1 collagen type I alpha 1 chain IEP
ISO 		associated with Graft vs Host Disease
mRNA, protein:increased expression:kidney cortex 		RGD PMID:21354048 PMID:7700025 PMID:7723234 RGD:5688301, RGD:5688333, RGD:5688332 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632 		JBrowse link
G CRP C-reactive protein no_association IDA
IAGP 		DNA:SNP RGD PMID:18852001 PMID:17596285 PMID:20039408 PMID:15692982 RGD:6907400, RGD:5508454, RGD:6909146, RGD:6909145 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CSF1 colony stimulating factor 1 ISO
IEP 		RGD PMID:21885670 PMID:17659436 RGD:7257567, RGD:7257589 NCBI chr 1:109,910,506...109,930,992
Ensembl chr 1:109,910,242...109,930,992 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 IDA RGD PMID:15146424 RGD:7204726 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965 		JBrowse link
G EGF epidermal growth factor IEP RGD PMID:21354048 RGD:5688301 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G FAS Fas cell surface death receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:33632240 PMID:38555047 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FCGR2A Fc gamma receptor IIa IAGP DNA:missense mutation:cds:p.H131R (human)
ClinVar Annotator: match by term: Lupus nephritis, susceptibility to 		ClinVar
RGD		 PMID:8636449 PMID:9843982 PMID:10675363 PMID:15367919 PMID:19915573 More... RGD:5147975 NCBI chr 1:161,505,457...161,524,048
Ensembl chr 1:161,505,430...161,524,013 		JBrowse link
G FCGR2B Fc gamma receptor IIb ISO RGD PMID:15681388 RGD:7240529 NCBI chr 1:161,647,243...161,678,654
Ensembl chr 1:161,663,143...161,678,654 		JBrowse link
G FCGR3A Fc gamma receptor IIIa susceptibility IAGP DNA:SNP:cds:p.V158F (human) RGD PMID:17596285 RGD:5508454 NCBI chr 1:161,541,759...161,550,737
Ensembl chr 1:161,541,759...161,550,968 		JBrowse link
G FCGR3B Fc gamma receptor IIIb EXP CTD Direct Evidence: marker/mechanism CTD PMID:16482158 NCBI chr 1:161,623,196...161,631,963
Ensembl chr 1:161,623,196...161,631,963 		JBrowse link
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 susceptibility IAGP DNA:polymorphisms:cds:HLA-DQA1*0101 (human)
DNA:polymorphisms:cds:HLA-DQA1*0102 (human) 		RGD PMID:12651073 PMID:12651073 RGD:40902999, RGD:40902999 NCBI chr 6:32,637,406...32,655,272
Ensembl chr 6:32,628,179...32,647,062 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 susceptibility IAGP DNA:polymorphisms:cds:HLA-DRB1*1501 (human) RGD PMID:12651073 RGD:40902999 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G IFNG interferon gamma IEP
EXP
IDA 		protein:increased expression:serum,urine
CTD Direct Evidence: marker/mechanism
protein:increased processing:kidney 		CTD
RGD		 PMID:31182691 PMID:22764573 PMID:29925830 RGD:6893369, RGD:14974252 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL17A interleukin 17A treatment ISO RGD PMID:25129462 RGD:9244623 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL18 interleukin 18 ISO RGD PMID:20980973 RGD:6893449 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,251...112,164,096 		JBrowse link
G IL1B interleukin 1 beta ISO mRNA:increased expression:renal glomerulus (mouse) RGD PMID:21641991 PMID:20410215 RGD:7175315, RGD:7175344 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1RN interleukin 1 receptor antagonist resistance IEP associated with Lupus Erythematosus, Systemic; protein:increased expression:serum (human) RGD PMID:20538031 RGD:6907068 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G ITGAM integrin subunit alpha M IAGP RGD PMID:21719445 RGD:5147916 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892 		JBrowse link
G JAK1 Janus kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:31182691 NCBI chr 1:64,833,229...65,067,746
Ensembl chr 1:64,833,223...65,067,754 		JBrowse link
G KLKB1 kallikrein B1 susceptibility IAGP DNA:SNPs:promoter: RGD PMID:19307730 RGD:7327150 NCBI chr 4:186,210,853...186,258,471
Ensembl chr 4:186,226,438...186,258,471 		JBrowse link
G MBL2 mannose binding lectin 2 disease_progression IAGP DNA:polymorphism:exon: RGD PMID:24850777 RGD:12910847 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G MIR125A microRNA 125a ISO RNA:decreased expression:kidney RGD PMID:30972208 RGD:26884458 NCBI chr19:51,693,254...51,693,339
Ensembl chr19:51,693,254...51,693,339 		JBrowse link
G MMP2 matrix metallopeptidase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22479529 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP9 matrix metallopeptidase 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22479529 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MPO myeloperoxidase susceptibility IAGP DNA:polymorphism: :−463G > A (human) RGD PMID:17896805 RGD:7174701 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO RGD PMID:17283580 RGD:7245502 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G MUC20 mucin 20, cell surface associated ISO RGD PMID:14565953 RGD:7364790 NCBI chr 3:195,720,978...195,733,551
Ensembl chr 3:195,720,884...195,741,123 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 ISO
IEP 		RGD PMID:21509671 PMID:17880936 RGD:7174713, RGD:7174734 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512 		JBrowse link
G OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 IEP protein:increased expression:kidney RGD PMID:22279542 RGD:7175260 NCBI chr11:63,986,438...63,998,412
Ensembl chr11:63,985,853...64,001,811 		JBrowse link
G PDCD1 programmed cell death 1 onset IAGP
ISO 		DNA:polymorphism: :
DNA:polymorphism:intron:6867 C>T (human) 		RGD PMID:15934088 PMID:21041733 PMID:15352422 RGD:7248675, RGD:7248678, RGD:7248676 NCBI chr 2:241,849,884...241,858,894
Ensembl chr 2:241,849,884...241,858,894 		JBrowse link
G SELL selectin L ISO RGD PMID:20512127 RGD:7175284 NCBI chr 1:169,690,667...169,711,620
Ensembl chr 1:169,690,665...169,711,702 		JBrowse link
G SERPING1 serpin family G member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:4014294 NCBI chr11:57,597,685...57,614,848
Ensembl chr11:57,597,387...57,619,171 		JBrowse link
G SNRPE small nuclear ribonucleoprotein polypeptide E treatment IDA mouse model RGD PMID:15494537 RGD:10760401 NCBI chr 1:203,861,599...203,871,152
Ensembl chr 1:203,861,599...203,871,152 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:31182691 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960 		JBrowse link
G STAT4 signal transducer and activator of transcription 4 ISO RGD PMID:20980973 RGD:6893449 NCBI chr 2:191,029,576...191,151,596
Ensembl chr 2:191,029,576...191,178,435 		JBrowse link
G STAT6 signal transducer and activator of transcription 6 disease_progression ISO RGD PMID:12874250 RGD:7244140 NCBI chr12:57,095,408...57,111,362
Ensembl chr12:57,095,408...57,132,139 		JBrowse link
G TLR7 toll like receptor 7 ISO RGD PMID:19944565 RGD:7246905 NCBI chr  X:12,867,072...12,890,361
Ensembl chr  X:12,867,072...12,890,361 		JBrowse link
G TLR9 toll like receptor 9 severity
treatment
no_association 		ISO
IEP
IAGP 		mRNA, protein:increased expression:kidney (mouse)
associated with Graft vs Host Disease
protein:increased expression:renal glomerulus (human)
associated with Lupus Erythematosus, Systemic; DNA:snps:promoter, intron:g.-1486T>C, g.+1174A>G (rs187084, rs352139) (human, North Indian)
DNA:snps:intron, exon:g.+1174G>A, g.+1635C>T (rs352139, rs352140) (human, Chinese) 		RGD PMID:23467932 PMID:17469139 PMID:21127878 PMID:19578108 PMID:22787315 More... RGD:7245987, RGD:7246911, RGD:7246897, RGD:7246896, RGD:7245989, RGD:7246884 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
G TNF tumor necrosis factor IEP protein:increased expression:glomerular mesangial cell RGD PMID:7750940 RGD:7394786 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b IEP associated with Lupus Erythematosus, Systemic;protein:increased expression:urine RGD PMID:21691937 RGD:7205483 NCBI chr 8:118,923,557...118,951,885
Ensembl chr 8:118,923,557...118,951,885 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A severity ISO
IEP 		RGD PMID:19201910 PMID:10906156 RGD:7245569, RGD:7245572 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B treatment IDA
ISO 		RGD PMID:22846145 PMID:22674120 RGD:7245541, RGD:7245544 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 severity IEP protein:increased expression:urine RGD PMID:22788914 RGD:7241032 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045 		JBrowse link
Lupus Vasculitis, Central Nervous System term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCGR3A Fc gamma receptor IIIa EXP CTD Direct Evidence: marker/mechanism CTD PMID:26773105 NCBI chr 1:161,541,759...161,550,737
Ensembl chr 1:161,541,759...161,550,968 		JBrowse link
G FCGR3B Fc gamma receptor IIIb EXP CTD Direct Evidence: marker/mechanism CTD PMID:26773105 NCBI chr 1:161,623,196...161,631,963
Ensembl chr 1:161,623,196...161,631,963 		JBrowse link
G INA internexin neuronal intermediate filament protein alpha severity IDA RGD PMID:20559547 RGD:40886275 NCBI chr10:103,277,138...103,290,346
Ensembl chr10:103,277,138...103,290,346 		JBrowse link
G ITGAM integrin subunit alpha M EXP CTD Direct Evidence: marker/mechanism CTD PMID:26773105 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892 		JBrowse link
G SELP selectin P IEP RGD PMID:20179168 RGD:6478687 NCBI chr 1:169,588,849...169,630,124
Ensembl chr 1:169,588,849...169,630,193 		JBrowse link
systemic lupus erythematosus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme IEA GAD PMID:15118671 RGD:1331525 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif 13 IEP protein:decreased expression:plasma (human) RGD PMID:12935979 RGD:10449040 NCBI chr 9:133,414,337...133,459,386
Ensembl chr 9:133,414,358...133,459,402 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO RGD PMID:19109165 RGD:5686827 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G AGER advanced glycosylation end-product specific receptor IAGP DNA:polymorphisms:promoter, intron:g.-429T>C rs1800625, g.-374T>A rs1800624, g.2184A>G rs3134940 (human) RGD PMID:22513366 RGD:6767309 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322 		JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO RGD PMID:21900645 RGD:6892717 NCBI chr  X:116,170,744...116,174,974
Ensembl chr  X:116,170,744...116,174,974 		JBrowse link
G ANXA3 annexin A3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr 4:78,551,770...78,610,447
Ensembl chr 4:78,551,747...78,610,451 		JBrowse link
G AP4B1-AS1 AP4B1 antisense RNA 1 IAGP ClinVar Annotator: match by term: Systemic lupus erythematosus ClinVar PMID:25741868 NCBI chr 1:113,812,612...113,901,237
Ensembl chr 1:113,812,379...113,901,237 		JBrowse link
G APOA1 apolipoprotein A1 treatment
severity 		ISO
IDA 		RGD PMID:20482780 PMID:20131231 RGD:7241863, RGD:7241864 NCBI chr11:116,835,751...116,837,622
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G ATG5 autophagy related 5 ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,325,791 		JBrowse link
G ATG7 autophagy related 7 ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665 		JBrowse link
G ATRIP ATR interacting protein IAGP ClinVar Annotator: match by term: Systemic lupus erythematosus ClinVar PMID:16845398 PMID:17293595 PMID:17660818 PMID:17660820 PMID:17846997 More... NCBI chr 3:48,446,779...48,467,645
Ensembl chr 3:48,446,710...48,467,645 		JBrowse link
G ATRIP ATR interacting protein IAGP ClinVar Annotator: match by term: Systemic lupus erythematosus ClinVar PMID:16845398 PMID:17293595 PMID:17660818 PMID:17660820 PMID:17846997 More... NCBI chr 3:48,446,737...48,467,645
Ensembl chr 3:48,446,710...48,467,645 		JBrowse link
G BANK1 B cell scaffold protein with ankyrin repeats 1 susceptibility IAGP
EXP 		DNA:SNPs:introns:
ClinVar Annotator: match by term: Systemic lupus erythematosus
CTD Direct Evidence: marker/mechanism 		ClinVar
CTD
RGD		 PMID:18204447 PMID:25741868 PMID:18204447 RGD:9684976 NCBI chr 4:101,790,730...102,074,812
Ensembl chr 4:101,411,286...102,074,812 		JBrowse link
G BECN1 beclin 1 ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350 		JBrowse link
G BLK BLK proto-oncogene, Src family tyrosine kinase IAGP
EXP 		DNA:snp:promoter:rs13277113 (human)
ClinVar Annotator: match by term: Systemic lupus erythematosus
CTD Direct Evidence: marker/mechanism 		ClinVar
CTD
RGD		 PMID:18204098 PMID:19667185 PMID:19838193 PMID:24023612 PMID:25741868 More... RGD:2316189 NCBI chr 8:11,494,387...11,564,599
Ensembl chr 8:11,486,894...11,564,599 		JBrowse link
G BLK-AS1 BLK antisense RNA 1 IAGP ClinVar Annotator: match by term: Systemic lupus erythematosus ClinVar PMID:18204098 PMID:19667185 PMID:24023612 PMID:25741868 PMID:28492532 More... NCBI chr 8:11,552,486...11,558,265 JBrowse link
G BLTP3A bridge-like lipid transfer protein family member 3A EXP CTD Direct Evidence: marker/mechanism CTD PMID:19838195 NCBI chr 6:34,792,083...34,877,514
Ensembl chr 6:34,792,083...34,877,514 		JBrowse link
G C1QA complement C1q A chain EXP
ISS 		CTD Direct Evidence: marker/mechanism
OMIM:152700 | OMIM:300809 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 		CTD
MouseDO		 PMID:8840296 NCBI chr 1:22,636,463...22,639,678
Ensembl chr 1:22,635,077...22,639,678 		JBrowse link
G C2 complement C2 IEP RGD PMID:6409476 RGD:7421516 NCBI chr 6:31,897,783...31,945,672
Ensembl chr 6:31,897,785...31,945,673 		JBrowse link
G C3 complement C3 severity IDA protein:increased processing RGD PMID:7510492 RGD:11040772 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G C3AR1 complement C3a receptor 1 ISO protein:increased expression:lung, leukocyte RGD PMID:17544263 RGD:5129560 NCBI chr12:8,056,844...8,066,359
Ensembl chr12:8,056,844...8,066,359 		JBrowse link
G C4A complement C4A (Chido/Rodgers blood group) IAGP RGD PMID:17503323 RGD:5688260 NCBI chr 6:31,982,057...32,002,681
Ensembl chr 6:31,982,057...32,002,681 		JBrowse link
G C4B complement C4B (Chido/Rodgers blood group) IAGP
ISS 		OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO
RGD		 PMID:17503323 RGD:5688260 NCBI chr 6:32,014,795...32,035,418
Ensembl chr 6:32,014,795...32,035,418 		JBrowse link
G C5AR1 complement C5a receptor 1 ISO protein:increased expression:lung, leukocyte RGD PMID:17544263 RGD:5129560 NCBI chr19:47,307,477...47,322,066
Ensembl chr19:47,290,023...47,322,066 		JBrowse link
G CA1 carbonic anhydrase 1 IDA RGD PMID:12806141 RGD:408425977 NCBI chr 8:85,327,608...85,378,113
Ensembl chr 8:85,327,608...85,379,014 		JBrowse link
G CA2 carbonic anhydrase 2 IDA RGD PMID:12806141 RGD:408425977 NCBI chr 8:85,464,007...85,481,493
Ensembl chr 8:85,463,968...85,481,493 		JBrowse link
G CAST calpastatin IDA RGD PMID:12367559 RGD:5683623 NCBI chr 5:95,961,429...96,774,683
Ensembl chr 5:96,247,756...96,779,595
Ensembl chr 5:96,247,756...96,779,595 		JBrowse link
G CAT catalase EXP CTD Direct Evidence: marker/mechanism CTD PMID:27497885 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 susceptibility
no_association 		IAGP DNA:snp:promoter:g.-2518A>G (human) RGD PMID:20414371 PMID:11844145 RGD:11528535, RGD:11528536 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL4 C-C motif chemokine ligand 4 disease_progression IEP protein:increased expression:serum RGD PMID:16924394 RGD:5683895 NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621 		JBrowse link
G CCR3 C-C motif chemokine receptor 3 severity IEP RGD PMID:21180278 RGD:6893428 NCBI chr 3:46,210,696...46,266,706
Ensembl chr 3:46,130,890...46,266,706 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 IEP mRNA:increased expression:blood, mononuclear cell RGD PMID:21180278 RGD:6893428 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206 		JBrowse link
G CD226 CD226 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:26808113 NCBI chr18:69,853,274...69,961,773
Ensembl chr18:69,831,158...69,961,803 		JBrowse link
G CD4 CD4 molecule treatment ISO RGD PMID:7914411 RGD:10058961 NCBI chr12:6,789,528...6,820,799
Ensembl chr12:6,786,858...6,820,799 		JBrowse link
G CD40 CD40 molecule susceptibility IAGP DNA:SNP: :rs4810485 (human)
DNA:SNP: :rs3765456 (human) 		RGD PMID:21914625 PMID:23256180 RGD:5490522, RGD:7248721 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CD40LG CD40 ligand IEP
ISS
EXP
ISO 		protein:increased expression:serum
OMIM:152700 | OMIM:300809 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420
CTD Direct Evidence: marker/mechanism 		MouseDO
CTD
RGD		 PMID:28793932 PMID:20726330 PMID:9036998 RGD:7248426, RGD:11352248 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390 		JBrowse link
G CD46 CD46 molecule severity IEP mRNA:increased expression:leukocyte (human) RGD PMID:22247341 RGD:6483457 NCBI chr 1:207,752,038...207,795,516
Ensembl chr 1:207,752,037...207,795,513 		JBrowse link
G CD80 CD80 molecule IEP RGD PMID:20653937 RGD:6902898 NCBI chr 3:119,524,293...119,559,614
Ensembl chr 3:119,524,293...119,559,614 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G CENPA centromere protein A HDA RGD PMID:28460084 RGD:36947378 NCBI chr 2:26,786,056...26,794,589
Ensembl chr 2:26,764,289...26,801,067 		JBrowse link
G CFB complement factor B EXP CTD Direct Evidence: marker/mechanism CTD PMID:19838195 NCBI chr 6:31,946,095...31,952,084
Ensembl chr 6:31,945,650...31,952,086 		JBrowse link
G CFH complement factor H susceptibility IAGP RGD PMID:21637784 RGD:5684554 NCBI chr 1:196,652,043...196,747,504
Ensembl chr 1:196,651,754...196,752,476 		JBrowse link
G CHAF1A chromatin assembly factor 1 subunit A IDA RGD PMID:24836587 RGD:9587742 NCBI chr19:4,402,640...4,450,830
Ensembl chr19:4,402,640...4,445,018 		JBrowse link
G CIITA class II major histocompatibility complex transactivator resistance
no_association 		IAGP DNA:polymorphism:intron:g.485A>G
DNA:polymorphism:promoter:rs3087456A, in a Japanese cohort A allele was protective/decreased risk of developing disease (p=0.006) 		RGD PMID:15897313 PMID:17693604 PMID:17711409 RGD:5491190, RGD:5491204, RGD:5491203 NCBI chr16:10,866,206...10,943,021
Ensembl chr16:10,866,222...10,943,021 		JBrowse link
G CLEC16A C-type lectin domain containing 16A EXP CTD Direct Evidence: marker/mechanism CTD PMID:19838195 NCBI chr16:10,944,564...11,182,186
Ensembl chr16:10,944,539...11,182,186 		JBrowse link
G CLU clusterin IEP
EXP 		protein:decreased expression:serum
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:15304052 PMID:10090169 RGD:8696021 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700 		JBrowse link
G CR2 complement C3d receptor 2 ISO
IAGP
EXP 		protein:decreased expression:B cell
ClinVar Annotator: match by term: Systemic lupus erythematosus, susceptibility to, 9
ClinVar Annotator: match by term: CR2-related condition | ClinVar Annotator: match by term: Systemic lupus erythematosus, susceptibility to, 9
CTD Direct Evidence: marker/mechanism 		ClinVar
OMIM
CTD
RGD		 PMID:9536098 PMID:17576681 PMID:24029428 PMID:24033266 PMID:25741868 More... RGD:127285806 NCBI chr 1:207,454,328...207,489,892
Ensembl chr 1:207,453,024...207,489,895 		JBrowse link
G CRP C-reactive protein disease_progression
no_association
treatment 		IDA
EXP 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17718048 PMID:17014014 PMID:20039408 PMID:8261665 RGD:6907402, RGD:6909146, RGD:6909144 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CSF1 colony stimulating factor 1 ISO RGD PMID:15383612 RGD:7257578 NCBI chr 1:109,910,506...109,930,992
Ensembl chr 1:109,910,242...109,930,992 		JBrowse link
G CSK C-terminal Src kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:23042117 NCBI chr15:74,782,080...74,803,197
Ensembl chr15:74,782,080...74,803,197 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 disease_progression ISO
IAGP
EXP 		ClinVar Annotator: match by term: Systemic lupus erythematosus
ClinVar Annotator: match by term: Systemic lupus erythematosus, susceptibility to
CTD Direct Evidence: marker/mechanism
DNA:polymorphisms:exons:Japanese(human) 		OMIM
ClinVar
CTD
RGD		 PMID:8817351 PMID:9259273 PMID:9398726 PMID:10189842 PMID:10475192 More... RGD:7204684, RGD:7204691 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965 		JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 severity IEP mRNA:increased expression:blood, mononuclear cell RGD PMID:21180278 RGD:6893428 NCBI chr 3:39,263,494...39,292,966
Ensembl chr 3:39,263,495...39,281,735 		JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 severity IEP RGD PMID:14596426 RGD:7257684 NCBI chr 2:218,125,294...218,137,251
Ensembl chr 2:218,125,289...218,137,251 		JBrowse link
G CYBB cytochrome b-245 beta chain ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr  X:37,780,059...37,813,461
Ensembl chr  X:37,780,018...37,813,461 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 susceptibility IAGP DNA:polymorphism:3' utr:3801T>C (rs4646903)
DNA:SNP: :4887C>A (human)
DNA:SNP: :p.I462V (human) 		RGD PMID:19561157 PMID:14611903 PMID:10599336 RGD:5147672, RGD:1581249, RGD:5147680 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G DEF6 DEF6 guanine nucleotide exchange factor EXP
ISS 		CTD Direct Evidence: marker/mechanism
OMIM:152700 | OMIM:300809 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 		CTD
MouseDO		 PMID:26808113 NCBI chr 6:35,297,818...35,321,771
Ensembl chr 6:35,297,818...35,321,771 		JBrowse link
G DNASE1 deoxyribonuclease 1 susceptibility IAGP
ISS
EXP 		ClinVar Annotator: match by term: Systemic lupus erythematosus, susceptibility to
ClinVar Annotator: match by term: DNASE1-related condition
OMIM:152700 | OMIM:300809 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420
CTD Direct Evidence: marker/mechanism 		ClinVar
MouseDO
CTD
OMIM		 PMID:10835632 PMID:11479590 PMID:15333586 PMID:18486922 PMID:24206041 More... NCBI chr16:3,611,760...3,665,461
Ensembl chr16:3,611,728...3,680,143 		JBrowse link
G DNASE1L3 deoxyribonuclease 1L3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22019780 NCBI chr 3:58,192,257...58,210,972
Ensembl chr 3:58,192,257...58,214,697 		JBrowse link
G DNASE2 deoxyribonuclease 2, lysosomal IAGP ClinVar Annotator: match by term: Systemic lupus erythematosus ClinVar NCBI chr19:12,875,209...12,881,449
Ensembl chr19:12,875,209...12,881,595 		JBrowse link
G DNMT1 DNA methyltransferase 1 no_association IEP mRNA:decreased expression:T cell: RGD PMID:21595664 PMID:18194272 RGD:9588656, RGD:9588670 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286 		JBrowse link
G ELN elastin IDA RGD PMID:12643515 RGD:9585739 NCBI chr 7:74,028,173...74,069,907
Ensembl chr 7:74,027,789...74,069,907 		JBrowse link
G ENG endoglin IAGP ClinVar Annotator: match by term: Systemic lupus erythematosus ClinVar PMID:9536098 PMID:17576681 PMID:28492532 PMID:32190976 NCBI chr 9:127,815,016...127,854,658
Ensembl chr 9:127,811,130...127,854,773 		JBrowse link
G EP300 E1A binding protein p300 ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,510...41,180,077 		JBrowse link
G EPOR erythropoietin receptor IDA RGD PMID:23151030 RGD:11041604 NCBI chr19:11,377,207...11,384,314
Ensembl chr19:11,377,207...11,384,342 		JBrowse link
G ESR2 estrogen receptor 2 susceptibility IAGP
ISO
IEP 		DNA:SNP: :rs4986938 (human)
mRNA:decreased expression:leukocyte,mononuclear
DNA:repeats:intron:
mRNA:increased expression: : 		RGD PMID:20961965 PMID:17336162 PMID:17874259 PMID:20305046 PMID:20627037 RGD:5508738, RGD:5508844, RGD:5508843, RGD:5508817, RGD:5508813 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G ETS1 ETS proto-oncogene 1, transcription factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:19838193 NCBI chr11:128,458,765...128,587,558
Ensembl chr11:128,458,761...128,587,558 		JBrowse link
G F2 coagulation factor II, thrombin susceptibility IAGP
IDA 		DNA:SNP: :19911A>G (rs3136516) (human) RGD PMID:21239755 PMID:20807656 RGD:5147772, RGD:5147776 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506 		JBrowse link
G FAM210B family with sequence similarity 210 member B ISS OMIM:152700 | OMIM:300809 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr20:56,358,974...56,368,663
Ensembl chr20:56,358,974...56,368,663 		JBrowse link
G FAS Fas cell surface death receptor susceptibility IAGP
EXP
ISS
IEP 		DNA:snps:promoter:g.-1377G>A, g.-670A>G (human)
CTD Direct Evidence: marker/mechanism
OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420
protein:increased expression:T lymphocyte:
protein:increased expression:serum (human) 		CTD
MouseDO
RGD		 PMID:36999444 PMID:23053964 PMID:7531628 PMID:9182923 RGD:8662433, RGD:11049450, RGD:8662437 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FCGR2A Fc gamma receptor IIa susceptibility
no_association 		IAGP
EXP
IDA
IEP 		CTD Direct Evidence: marker/mechanism
DNA:polymorphism:cds:p.H131R (human)
protein:decreased expression:blood, monocyte
DNA:SNP (human) 		OMIM
CTD
RGD		 PMID:18204446 PMID:21719445 PMID:8254199 PMID:11561111 PMID:14747618 More... RGD:5147916, RGD:5147984, RGD:5147979, RGD:5147976, RGD:5147973, RGD:5147972, RGD:5147926 NCBI chr 1:161,505,457...161,524,048
Ensembl chr 1:161,505,430...161,524,013 		JBrowse link
G FCGR2B Fc gamma receptor IIb no_association
severity
susceptibility
treatment 		IAGP
ISS
EXP
ISO 		OMIM:152700 | OMIM:300809 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Systemic lupus erythematosus, susceptibility to
DNA:SNPs:exon, intron:10849T>C (rs1050501), 10950T>G (rs6666965) (human)
DNA:SNP:intron:11045G>T (rs12117530) (human)
DNA:snp:promoter:g.-386G>C (rs3219018) (human)
DNA:snps, haplotype:promoter:g.-386G>C, g.-120T>A (human) 		OMIM
MouseDO
CTD
ClinVar
RGD		 PMID:12115230 PMID:15459183 PMID:15895258 PMID:16115811 PMID:16170323 More... RGD:7240540, RGD:11056171, RGD:11056171, RGD:1547880, RGD:1547879, RGD:9588603, RGD:9588566 NCBI chr 1:161,647,243...161,678,654
Ensembl chr 1:161,663,143...161,678,654 		JBrowse link
G FCGR3A Fc gamma receptor IIIa susceptibility IEP
IAGP 		protein:decreased expression:NK cell
DNA:CNVs
DNA:SNPs:exon:rs403016,rs428888(human) 		RGD PMID:21370226 PMID:25154742 PMID:18625651 RGD:5508389, RGD:11344974, RGD:5508444 NCBI chr 1:161,541,759...161,550,737
Ensembl chr 1:161,541,759...161,550,968 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 susceptibility IAGP DNA:deletion: : RGD PMID:20226777 RGD:5490989 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:11436868 NCBI chr 6:32,637,406...32,655,272
Ensembl chr 6:32,628,179...32,647,062 		JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 susceptibility IAGP DNA:polymorphisms: :multiple (human)
DNA:polymorphisms:cds:HLA-DQB1*0201 (human) 		RGD PMID:21658414 PMID:12651073 PMID:18552411 RGD:5147560, RGD:40902999, RGD:5147620 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 susceptibility IAGP
EXP 		DNA:polymorphisms: :multiple (human)
DNA:polymorphisms:cds:HLA-DRB1*0301 (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphisms:cds:HLA-DRB1*0301, HLA-DRB1*1501 (human) 		CTD
RGD		 PMID:11436868 PMID:21658414 PMID:12651073 PMID:20191587 RGD:5147560, RGD:40902999, RGD:5147581 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A IAGP DNA:SNP: :rs1043618 (human) RGD PMID:20498198 RGD:5147600 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946 		JBrowse link
G HSPA1L heat shock protein family A (Hsp70) member 1 like IAGP DNA:SNPs: :rs2075800, rs2227956 (human) RGD PMID:20498198 RGD:5147600 NCBI chr 6:31,809,619...31,815,283
Ensembl chr 6:31,809,619...31,815,283 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 IEP protein:increased expression:serum: RGD PMID:8255671 RGD:12910480 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737 		JBrowse link
G IFIH1 interferon induced with helicase C domain 1 EXP
ISS 		CTD Direct Evidence: marker/mechanism
OMIM:152700 | OMIM:300809 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 		CTD
MouseDO		 PMID:19838195 PMID:24686847 NCBI chr 2:162,267,074...162,318,684
Ensembl chr 2:162,267,074...162,318,684 		JBrowse link
G IFNG interferon gamma IEP
ISO 		mRNA:increased expression:leukocyte,mononuclear
mRNA:increased expression:kidney (human)
protein:increased expression:renal glomerulus 		RGD PMID:22759859 PMID:22660635 PMID:29925830 RGD:6893373, RGD:155663483, RGD:14974252 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IKZF1 IKAROS family zinc finger 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19838193 NCBI chr 7:50,303,455...50,405,101
Ensembl chr 7:50,304,068...50,405,101 		JBrowse link
G IKZF3 IKAROS family zinc finger 3 ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr17:39,757,715...39,864,312
Ensembl chr17:39,757,715...39,864,312 		JBrowse link
G IL10 interleukin 10 IAGP
EXP 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19838195 PMID:20728533 PMID:12486603 RGD:1580478 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL12B interleukin 12B EXP CTD Direct Evidence: marker/mechanism CTD PMID:19838195 PMID:26808113 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G IL13 interleukin 13 IEP protein:increased expression:serum RGD PMID:12051401 RGD:8549582 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G IL17A interleukin 17A IEP protein:increased expression:epidermis (human)
mRNA:increased expression:kidney (human) 		RGD PMID:20493423 PMID:22660635 RGD:8698667, RGD:155663483 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL1B interleukin 1 beta IAGP
IEP 		DNA:SNPs, haplotype:promoter:-511C>T, 3953C>T (human)
mRNA:increased expression:kidney (human) 		RGD PMID:15470475 PMID:22660635 RGD:7401214, RGD:155663483 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1RN interleukin 1 receptor antagonist IEP
IAGP 		protein:increased expression:plasma (human)
DNA:polymorphism:exon:g.14709C>T rs315952 (human) 		RGD PMID:20805419 PMID:17176440 RGD:6906963, RGD:6907356 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL2 interleukin 2 IDA RGD PMID:6421522 RGD:8662948 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL21 interleukin 21 susceptibility EXP
IAGP 		CTD Direct Evidence: marker/mechanism
DNA:SNP:intron: (rs907715) (human) 		CTD
RGD		 PMID:17911475 PMID:23236436 RGD:127285363 NCBI chr 4:122,610,108...122,621,066
Ensembl chr 4:122,610,108...122,621,066 		JBrowse link
G IL21R interleukin 21 receptor ISO
EXP
IAGP 		CTD Direct Evidence: therapeutic
DNA:polymorphism: : rs3093301 (human) 		CTD
RGD		 PMID:17911475 PMID:20424514 PMID:19164519 PMID:19644854 RGD:6892931, RGD:6892937, RGD:6892933 NCBI chr16:27,402,174...27,452,042
Ensembl chr16:27,402,174...27,452,042 		JBrowse link
G IL23R interleukin 23 receptor IEP protein:increased expression:T cell: RGD PMID:21110900 RGD:8549601 NCBI chr 1:67,138,637...67,265,903
Ensembl chr 1:67,138,907...67,259,979 		JBrowse link
G IL4 interleukin 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18158872 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL5 interleukin 5 IEP RGD PMID:23054011 RGD:7241039 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838 		JBrowse link
G IL6 interleukin 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18158872 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INPP5D inositol polyphosphate-5-phosphatase D ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr 2:233,060,342...233,207,903
Ensembl chr 2:233,059,967...233,207,903 		JBrowse link
G IRAK4 interleukin 1 receptor associated kinase 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28003376 NCBI chr12:43,758,951...43,789,541
Ensembl chr12:43,758,944...43,798,307 		JBrowse link
G IRF5 interferon regulatory factor 5 IAGP
EXP 		ClinVar Annotator: match by term: Systemic lupus erythematosus, susceptibility to, 10
ClinVar Annotator: match by term: Systemic lupus erythematosus, association with susceptibility to, 10
CTD Direct Evidence: marker/mechanism 		ClinVar
OMIM
CTD		 PMID:15657875 PMID:16642019 PMID:17189288 PMID:17393452 PMID:17476532 More... NCBI chr 7:128,937,032...128,950,038
Ensembl chr 7:128,937,457...128,950,038 		JBrowse link
G IRF8 interferon regulatory factor 8 susceptibility IAGP DNA:SNP: (rs4843869) (human) RGD PMID:27021335 RGD:329961559 NCBI chr16:85,899,162...85,922,609
Ensembl chr16:85,899,116...85,922,606 		JBrowse link
G ITGAM integrin subunit alpha M EXP CTD Direct Evidence: marker/mechanism CTD PMID:18204446 PMID:18204448 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892 		JBrowse link
G JAK1 Janus kinase 1 ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr 1:64,833,229...65,067,746
Ensembl chr 1:64,833,223...65,067,754 		JBrowse link
G JAK2 Janus kinase 2 ISO RGD PMID:21880982 RGD:6483022 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948 		JBrowse link
G JAZF1 JAZF zinc finger 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19838195 NCBI chr 7:27,830,577...28,180,795
Ensembl chr 7:27,830,573...28,180,795 		JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315 		JBrowse link
G KLKB1 kallikrein B1 susceptibility IAGP DNA:SNPs:promoter: RGD PMID:19307730 RGD:7327150 NCBI chr 4:186,210,853...186,258,471
Ensembl chr 4:186,226,438...186,258,471 		JBrowse link
G LBR lamin B receptor ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr 1:225,401,502...225,428,821
Ensembl chr 1:225,401,502...225,428,925 		JBrowse link
G LDLR low density lipoprotein receptor IEP mRNA:decreased expression:leukocyte RGD PMID:19811272 RGD:5490253 NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820 		JBrowse link
G LOC126805994 BRD4-independent group 4 enhancer GRCh37_chr1:207642622-207643821 IAGP ClinVar Annotator: match by term: CR2-related condition
ClinVar Annotator: match by term: Systemic lupus erythematosus, susceptibility to, 9
ClinVar Annotator: match by term: CR2-related condition | ClinVar Annotator: match by term: Systemic lupus erythematosus, susceptibility to, 9 		ClinVar PMID:25741868 PMID:28492532 NCBI chr 1:207,469,277...207,470,476 JBrowse link
G LOC126860303 CDK7 strongly-dependent group 2 enhancer GRCh37_chr8:11407118-11408317 IAGP ClinVar Annotator: match by term: Systemic lupus erythematosus ClinVar PMID:18204098 PMID:19667185 PMID:24023612 PMID:25741868 PMID:28492532 More... NCBI chr 8:11,549,609...11,550,808 JBrowse link
G LOC130058479 ATAC-STARR-seq lymphoblastoid silent region 7198 IAGP ClinVar Annotator: match by term: Systemic lupus erythematosus ClinVar PMID:33087723 NCBI chr16:11,255,350...11,255,499 JBrowse link
G LPA lipoprotein(a) IEP protein:increased ezpression:serum RGD PMID:20026018 RGD:5509911 NCBI chr 6:160,531,482...160,664,275
Ensembl chr 6:160,531,482...160,664,275 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr 8:55,879,835...56,014,169
Ensembl chr 8:55,879,835...56,014,169 		JBrowse link
G MAN2A1 mannosidase alpha class 2A member 1 ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr 5:109,689,927...109,869,625
Ensembl chr 5:109,689,927...109,869,625 		JBrowse link
G MBL2 mannose binding lectin 2 susceptibility IAGP DNA:SNP:exon
DNA:SNP,haplotype:cds:p.G54D,G57E(human) 		RGD PMID:21510992 PMID:11561111 RGD:6903266, RGD:5147979 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G MEFV MEFV innate immunity regulator, pyrin IAGP ClinVar Annotator: match by term: Systemic lupus erythematosus ClinVar PMID:5458961 PMID:7677151 PMID:9668175 PMID:10090880 PMID:10737995 More... NCBI chr16:3,242,027...3,256,633
Ensembl chr16:3,242,027...3,256,633 		JBrowse link
G MIR146A microRNA 146a IEP
ISO 		mRNA:increased expression:kidney (human)
mRNA:increased expression:kidney (mouse) 		RGD PMID:22660635 PMID:22660635 RGD:155663483, RGD:155663483 NCBI chr 5:160,485,352...160,485,450
Ensembl chr 5:160,485,352...160,485,450 		JBrowse link
G MIR196A2 microRNA 196a-2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27816459 NCBI chr12:53,991,738...53,991,847
Ensembl chr12:53,991,738...53,991,847 		JBrowse link
G MIR23B microRNA 23b treatment IEP
ISO 		mRNA, protein:decreased expression:kidney (human)
mRNA:decreased expression:kidney (mouse) 		RGD PMID:22660635 PMID:22660635 PMID:22660635 RGD:155663483, RGD:155663483, RGD:155663483 NCBI chr 9:95,085,208...95,085,304
Ensembl chr 9:95,085,208...95,085,304 		JBrowse link
G MKI67 marker of proliferation Ki-67 IEP RGD PMID:21693493 RGD:6483529 NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423 		JBrowse link
G MMD monocyte to macrophage differentiation associated IEP associated with Pregnancy Complications;mRNA:increased expression:blood (human) RGD PMID:31684818 RGD:155630630 NCBI chr17:55,392,622...55,421,835
Ensembl chr17:55,392,622...55,421,924 		JBrowse link
G MMP1 matrix metallopeptidase 1 IEP protein:increased expression:plasma (human) RGD PMID:9972954 RGD:7207129 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160 		JBrowse link
G MT-ATP6 mitochondrially encoded ATP synthase membrane subunit 6 IAGP DNA:transition:cds:m.9055A>G (human) RGD PMID:18708297 RGD:5490259 NCBI chr MT:8,527...9,207
Ensembl chr MT:8,527...9,207 		JBrowse link
G MTA2 metastasis associated 1 family member 2 ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr11:62,593,214...62,601,865
Ensembl chr11:62,593,214...62,601,865 		JBrowse link
G NAT2 N-acetyltransferase 2 susceptibility IAGP DNA:polymorphism: : RGD PMID:10599336 RGD:5147680 NCBI chr 8:18,386,301...18,401,218
Ensembl chr 8:18,391,282...18,401,218 		JBrowse link
G NCF1 neutrophil cytosolic factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28135245 NCBI chr 7:74,774,011...74,789,315
Ensembl chr 7:74,774,011...74,789,315 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 susceptibility IEP
IAGP 		protein:increased expression:monocyte
DNA:mutation:cds:p.G908R (rs2066845)(human) 		RGD PMID:21886831 PMID:16642031 RGD:5508746, RGD:13204710 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO mRNA:increased expression:bone marrow macrophage (mouse) RGD PMID:22011580 RGD:5508848 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G P2RY12 purinergic receptor P2Y12 IEP
EXP 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:15304052 PMID:15304052 RGD:6480537 NCBI chr 3:151,336,843...151,384,753
Ensembl chr 3:151,336,843...151,384,753 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO RGD PMID:17182544 RGD:11074797 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PCNX3 pecanex 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26808113 NCBI chr11:65,615,776...65,637,439
Ensembl chr11:65,615,776...65,637,439 		JBrowse link
G PDCD1 programmed cell death 1 IAGP
ISS
IDA 		DNA:polymorphism: : 7,146 G>A (human)
OMIM:152700 | OMIM:300809 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 		MouseDO
RGD		 PMID:17228327 PMID:19116915 RGD:7248674, RGD:7248679 NCBI chr 2:241,849,884...241,858,894
Ensembl chr 2:241,849,884...241,858,894 		JBrowse link
G PGF placental growth factor IEP protein:increased expression:serum RGD PMID:19276301 RGD:6483612 NCBI chr14:74,941,830...74,955,764
Ensembl chr14:74,941,834...74,955,626 		JBrowse link
G PHRF1 PHD and ring finger domains 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18204446 NCBI chr11:576,470...612,222
Ensembl chr11:576,470...612,222 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:16365454 RGD:6482698 NCBI chr 7:106,865,282...106,908,980
Ensembl chr 7:106,865,278...106,908,980 		JBrowse link
G PLD4 phospholipase D family member 4 ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr14:104,924,879...104,937,785
Ensembl chr14:104,924,713...104,937,761 		JBrowse link
G POLB DNA polymerase beta ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr 8:42,338,494...42,371,808
Ensembl chr 8:42,338,454...42,371,808 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PPP2R2B protein phosphatase 2 regulatory subunit Bbeta IEP RGD PMID:21746932 RGD:5686291 NCBI chr 5:146,580,742...147,081,520
Ensembl chr 5:146,580,742...147,084,784 		JBrowse link
G PRDM1 PR/SET domain 1 EXP
ISS 		CTD Direct Evidence: marker/mechanism
OMIM:152700 | OMIM:300809 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 		CTD
MouseDO		 PMID:19838195 NCBI chr 6:105,992,690...106,109,938
Ensembl chr 6:105,993,463...106,109,939 		JBrowse link
G PRF1 perforin 1 severity IEP RGD PMID:21906646 RGD:6482798 NCBI chr10:70,597,348...70,602,741
Ensembl chr10:70,597,348...70,602,759 		JBrowse link
G PRL prolactin EXP CTD Direct Evidence: marker/mechanism CTD PMID:14870917 NCBI chr 6:22,287,246...22,302,835
Ensembl chr 6:22,287,244...22,302,826 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17761345 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 susceptibility IAGP
EXP 		DNA:missense mutation:cds:p.R620W (human)
ClinVar Annotator: match by term: Systemic lupus erythematosus
CTD Direct Evidence: marker/mechanism
DNA:snp:cds:c.1858C>T (human)
DNA:snp:introns:c.87+1492C>T, c.828+186G>A (rs1217414, rs3765598) (human)
DNA:missense mutation:cds:p.R263Q (human) 		ClinVar
OMIM
CTD
RGD		 PMID:18204446 PMID:21190368 PMID:25741868 PMID:17092257 PMID:23076337 More... RGD:5147973, RGD:11534992, RGD:11533999, RGD:11532755 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr 1:198,638,713...198,757,476
Ensembl chr 1:198,638,457...198,759,342 		JBrowse link
G PXK PX domain containing serine/threonine kinase like EXP CTD Direct Evidence: marker/mechanism CTD PMID:18204446 NCBI chr 3:58,332,892...58,426,127
Ensembl chr 3:58,332,880...58,426,127 		JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 EXP
ISS 		CTD Direct Evidence: marker/mechanism
OMIM:152700 | OMIM:300809 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 		CTD
MouseDO		 PMID:26808113 NCBI chr15:38,488,103...38,564,814
Ensembl chr15:38,488,103...38,565,575 		JBrowse link
G RASGRP3 RAS guanyl releasing protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19838193 NCBI chr 2:33,436,348...33,564,731
Ensembl chr 2:33,436,324...33,586,669 		JBrowse link
G RASSF5 Ras association domain family member 5 ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr 1:206,507,531...206,589,448
Ensembl chr 1:206,507,531...206,589,448 		JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr 1:173,931,084...174,022,357
Ensembl chr 1:173,931,084...174,022,357 		JBrowse link
G RETN resistin IEP RGD PMID:21885493 RGD:7207148 NCBI chr19:7,669,049...7,670,455
Ensembl chr19:7,669,049...7,670,455 		JBrowse link
G RO60 Ro60, Y RNA binding protein ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr 1:193,059,612...193,091,777
Ensembl chr 1:193,059,454...193,091,777 		JBrowse link
G RPL12 ribosomal protein L12 IDA RGD PMID:11161982 RGD:11035232 NCBI chr 9:127,447,674...127,451,406
Ensembl chr 9:127,447,674...127,451,406 		JBrowse link
G RPL14 ribosomal protein L14 IDA RGD PMID:12051391 RGD:11036103 NCBI chr 3:40,457,339...40,468,587
Ensembl chr 3:40,457,292...40,468,587 		JBrowse link
G RUBCN rubicon autophagy regulator ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr 3:197,668,867...197,749,820
Ensembl chr 3:197,668,867...197,749,727 		JBrowse link
G RXRA retinoid X receptor alpha ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr 9:134,326,455...134,440,585
Ensembl chr 9:134,317,098...134,440,585 		JBrowse link
G SELL selectin L IEP RGD PMID:20512127 RGD:7175284 NCBI chr 1:169,690,667...169,711,620
Ensembl chr 1:169,690,665...169,711,702 		JBrowse link
G SFTPD surfactant protein D IEP protein:decreased expression:serum RGD PMID:19833760 RGD:4143493 NCBI chr10:79,937,740...79,982,383
Ensembl chr10:79,937,467...79,982,614 		JBrowse link
G SH2B3 SH2B adaptor protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19838195 NCBI chr12:111,404,730...111,451,623
Ensembl chr12:111,405,923...111,451,623 		JBrowse link
G SIGLEC6 sialic acid binding Ig like lectin 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26808113 NCBI chr19:51,517,819...51,531,670
Ensembl chr19:51,517,819...51,531,856 		JBrowse link
G SLC11A1 solute carrier family 11 member 1 IAGP DNA:deletion:3' utr: (human) RGD PMID:21233146 RGD:5684928 NCBI chr 2:218,382,273...218,396,894
Ensembl chr 2:218,382,029...218,396,894 		JBrowse link
G SLC15A4 solute carrier family 15 member 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19838193 NCBI chr12:128,793,194...128,823,958
Ensembl chr12:128,793,194...128,823,958 		JBrowse link
G SNRNP70 small nuclear ribonucleoprotein U1 subunit 70 ISO
IDA 		RGD PMID:10940910 PMID:22454191 RGD:10448935, RGD:10448939 NCBI chr19:49,085,451...49,108,604
Ensembl chr19:49,085,419...49,108,605 		JBrowse link
G SNRPC small nuclear ribonucleoprotein polypeptide C IDA RGD PMID:8647956 RGD:10766446 NCBI chr 6:34,757,505...34,773,857
Ensembl chr 6:34,757,505...34,773,857 		JBrowse link
G SNRPD1 small nuclear ribonucleoprotein D1 polypeptide severity IDA mouse model RGD PMID:12571858 RGD:10755713 NCBI chr18:21,612,314...21,633,520
Ensembl chr18:21,612,314...21,633,524 		JBrowse link
G SNRPD2 small nuclear ribonucleoprotein D2 polypeptide IDA RGD PMID:11823543 RGD:10766471 NCBI chr19:45,687,454...45,692,316
Ensembl chr19:45,687,460...45,692,569 		JBrowse link
G SNRPD3 small nuclear ribonucleoprotein D3 polypeptide IDA RGD PMID:17640359 RGD:10755704 NCBI chr22:24,555,650...24,574,971
Ensembl chr22:24,555,958...24,582,052 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 ISO
IAGP 		ClinVar Annotator: match by term: Systemic lupus erythematosus ClinVar
RGD		 PMID:33087723 PMID:14499118 RGD:150573686 NCBI chr16:11,254,417...11,256,204
Ensembl chr16:11,254,417...11,256,204 		JBrowse link
G SOD2 superoxide dismutase 2 IAGP DNA:SNP, haplotype: :1183C>T (human) RGD PMID:14611903 RGD:1581249 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G STAT4 signal transducer and activator of transcription 4 onset
treatment 		ISO
IAGP
EXP 		ClinVar Annotator: match by term: STAT4-related condition
ClinVar Annotator: match by term: Systemic lupus erythematosus, susceptibility to, 11
CTD Direct Evidence: marker/mechanism
DNA:SNPs:intron:multiple (human)
DNA:SNPs:introns:c.274-23582A>C, c.274-2691G>A, c.466-1307G>A (rs7574865, rs11889341, rs10168266) (human)
DNA:SNP:intron:c.274-28828C>G (rs10181656) (human)
DNA:SNP:intron:c.274-23582A>C (rs7574865) (human)
DNA:SNP:intron:c.274-29069G>C (rs7582694) (human) 		OMIM
ClinVar
CTD
RGD		 PMID:17804842 PMID:18204446 PMID:19109131 PMID:19838193 PMID:19838195 More... RGD:7207867, RGD:7207881, RGD:7207879, RGD:7207878, RGD:7207877, RGD:7207874, RGD:7207869 NCBI chr 2:191,029,576...191,151,596
Ensembl chr 2:191,029,576...191,178,435 		JBrowse link
G SYNGR1 synaptogyrin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26808113 NCBI chr22:39,349,991...39,385,575
Ensembl chr22:39,349,925...39,385,575 		JBrowse link
G TAB2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 IEP mRNA, protein:increased expression:kidney (human) RGD PMID:22660635 RGD:155663483 NCBI chr 6:149,217,926...149,411,607
Ensembl chr 6:149,218,641...149,411,613 		JBrowse link
G TAB3 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 IEP mRNA, protein:increased expression:kidney (human) RGD PMID:22660635 RGD:155663483 NCBI chr  X:30,827,442...30,889,254
Ensembl chr  X:30,827,442...30,975,084 		JBrowse link
G TAP1 transporter 1, ATP binding cassette subfamily B member no_association IAGP RGD PMID:9014588 RGD:6482277 NCBI chr 6:32,845,209...32,853,704
Ensembl chr 6:32,845,209...32,853,816 		JBrowse link
G TAP2 transporter 2, ATP binding cassette subfamily B member susceptibility
no_association 		IAGP RGD PMID:12634240 PMID:9014588 RGD:6482273, RGD:6482277 NCBI chr 6:32,821,831...32,838,739
Ensembl chr 6:32,821,833...32,838,739 		JBrowse link
G TCF7 transcription factor 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26808113 NCBI chr 5:134,108,218...134,148,210
Ensembl chr 5:134,114,681...134,151,865 		JBrowse link
G TERT telomerase reverse transcriptase EXP CTD Direct Evidence: marker/mechanism CTD PMID:26808113 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068 		JBrowse link
G TFPI tissue factor pathway inhibitor IEP protein:decreased expression:plasma: RGD PMID:11709459 RGD:11060258 NCBI chr 2:187,464,230...187,554,435
Ensembl chr 2:187,464,230...187,565,760 		JBrowse link
G THBD thrombomodulin IEP protein:increased expression:serum RGD PMID:18484695 RGD:5684995 NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672 		JBrowse link
G TIMD4 T cell immunoglobulin and mucin domain containing 4 ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr 5:156,919,292...156,963,226
Ensembl chr 5:156,919,292...156,963,226 		JBrowse link
G TLR4 toll like receptor 4 ISO RGD PMID:19841185 RGD:7241088 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR5 toll like receptor 5 susceptibility IAGP
EXP 		ClinVar Annotator: match by term: Systemic lupus erythematosus, resistance to, 1
ClinVar Annotator: match by term: Systemic lupus erythematosus, susceptibility to, 1
CTD Direct Evidence: marker/mechanism 		ClinVar
OMIM
CTD		 PMID:14623910 PMID:16027372 PMID:23447684 PMID:25741868 NCBI chr 1:223,109,404...223,143,248
Ensembl chr 1:223,109,404...223,143,292 		JBrowse link
G TLR7 toll like receptor 7 ISS
IAGP 		OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420
ClinVar Annotator: match by term: Systemic lupus erythematosus 		MouseDO
ClinVar		 PMID:35477763 NCBI chr  X:12,867,072...12,890,361
Ensembl chr  X:12,867,072...12,890,361 		JBrowse link
G TLR9 toll like receptor 9 susceptibility
severity 		IAGP
ISO 		DNA:snp:exon:c.1635C>T rs352140 (human)
mRNA:increased expression:B lymphocyte (mouse) 		RGD PMID:19130296 PMID:21592581 PMID:16973389 RGD:5130767, RGD:7246894, RGD:7245988 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
G TNF tumor necrosis factor IEP
IAGP 		protein:increased expression:serum
mRNA:increased expression:kidney (human)
ClinVar Annotator: match by term: Systemic lupus erythematosus, susceptibility to
DNA:polymorphisms, haplotype:promoter:multiple (human) 		ClinVar
RGD		 PMID:8056188 PMID:9818939 PMID:10450718 PMID:11261930 PMID:11506397 More... RGD:7245570, RGD:155663483, RGD:7245571 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19165918 PMID:19165919 PMID:19838193 PMID:21336280 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
G TNFRSF13B TNF receptor superfamily member 13B ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr17:16,939,081...16,972,118
Ensembl chr17:16,929,816...16,972,118 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A severity IEP protein:increased expression:serum RGD PMID:8393677 RGD:7245539 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B severity
no_association 		IEP
IAGP 		protein:increased expression:serum
DNA:missense mutation:cds:p.M196R (human) 		RGD PMID:8393677 PMID:11607787 RGD:7245539, RGD:7245571 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228 		JBrowse link
G TNFSF4 TNF superfamily member 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18059267 PMID:19838193 NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,162,645...173,477,583 		JBrowse link
G TNIP1 TNFAIP3 interacting protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19838193 PMID:19838195 NCBI chr 5:151,029,943...151,087,685
Ensembl chr 5:151,029,945...151,093,577 		JBrowse link
G TRAF3IP2 TRAF3 interacting protein 2 ISS OMIM:152700 | OMIM:300809 | OMIM:601744 | OMIM:605218 | OMIM:605480 | OMIM:608437 | OMIM:609903 | OMIM:609939 | OMIM:610065 | OMIM:610066 | OMIM:610927 | OMIM:612251 | OMIM:612253 | OMIM:612254 | OMIM:612378 | OMIM:613145 | OMIM:614420 MouseDO NCBI chr 6:111,555,381...111,605,878
Ensembl chr 6:111,555,381...111,606,906 		JBrowse link
G TREX1 three prime repair exonuclease 1 EXP
IAGP 		CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Systemic lupus erythematosus 		CTD
OMIM
ClinVar		 PMID:16845398 PMID:17293595 PMID:17660818 PMID:17660820 PMID:17846997 More... NCBI chr 3:48,465,830...48,467,645
Ensembl chr 3:48,465,811...48,467,645 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 severity IEP RGD PMID:18693542 RGD:7241211 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045 		JBrowse link
G VIM vimentin IDA RGD PMID:3780056 RGD:6480476 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
G YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta IEA GAD PMID:15118671 RGD:1331525 NCBI chr20:44,885,705...44,908,532
Ensembl chr20:44,885,702...44,908,532 		JBrowse link
Systemic Lupus Erythematosus 16 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNASE1L3 deoxyribonuclease 1L3 IAGP ClinVar Annotator: match by term: Systemic lupus erythematosus 16
ClinVar Annotator: match by term: DNASE1L3-related condition | ClinVar Annotator: match by term: Systemic lupus erythematosus 16 		OMIM
ClinVar		 PMID:21692081 PMID:22019780 PMID:24206041 PMID:25741868 PMID:27821515 More... NCBI chr 3:58,192,257...58,210,972
Ensembl chr 3:58,192,257...58,214,697 		JBrowse link
Systemic Lupus Erythematosus 17 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TLR7 toll like receptor 7 IAGP ClinVar Annotator: match by term: Systemic lupus erythematosus 17 OMIM
ClinVar		 PMID:28492532 PMID:35477763 NCBI chr  X:12,867,072...12,890,361
Ensembl chr  X:12,867,072...12,890,361 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 151455
    disease of anatomical entity 138485
      musculoskeletal system disease 29210
        autoimmune disease of musculoskeletal system 9012
          lupus erythematosus 1725
            cutaneous lupus erythematosus + 33
            drug-induced lupus erythematosus 0
            systemic lupus erythematosus + 1702
Path 2
Term Annotations click to browse term
  disease 151455
    disease of anatomical entity 138485
      Immune & Inflammatory Diseases 28050
        immune system disease 23853
          primary immunodeficiency disease 18105
            autoimmune disease 13982
              autoimmune disease of musculoskeletal system 9012
                lupus erythematosus 1725
                  cutaneous lupus erythematosus + 33
                  drug-induced lupus erythematosus 0
                  systemic lupus erythematosus + 1702
paths to the root