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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:substance-induced psychosis
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Accession:DOID:8646 term browser browse the term
Definition:Psychotic organic mental disorders resulting from the toxic effect of drugs and chemicals or other harmful substance.
Synonyms:exact_synonym: Drug Psychoses;   Toxic Psychoses;   substance-induced psychoses
 primary_id: MESH:D011605;   RDO:0006434
 xref: ICD9CM:293.89
For additional species annotation, visit the Alliance of Genome Resources.

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substance-induced psychosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO CTD Direct Evidence: marker/mechanism CTD PMID:17196621 NCBI chrNW_004624849:998,262...1,019,305
Ensembl chrNW_004624849:998,277...1,019,521 		JBrowse link
G Adora2a adenosine A2a receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20799992 NCBI chrNW_004624747:9,846,254...9,860,938
Ensembl chrNW_004624747:9,851,153...9,860,094 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21041608 NCBI chrNW_004624734:507,880...525,295
Ensembl chrNW_004624734:509,368...525,295 		JBrowse link
G Camk2b calcium/calmodulin dependent protein kinase II beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:17603807 NCBI chrNW_004624740:7,750,327...7,828,891
Ensembl chrNW_004624740:7,750,245...7,831,454 		JBrowse link
G Esr1 estrogen receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19386276 NCBI chrNW_004624785:6,164,507...6,601,302
Ensembl chrNW_004624785:6,164,379...6,601,326 		JBrowse link
G Grm2 glutamate metabotropic receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20211215 NCBI chrNW_004624730:5,419,892...5,431,268
Ensembl chrNW_004624730:5,419,896...5,431,361 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19747927 NCBI chrNW_004624815:5,817,196...5,821,197
Ensembl chrNW_004624815:5,816,601...5,820,864 		JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20705401 NCBI chrNW_004624764:4,778,563...4,791,505
Ensembl chrNW_004624764:4,778,657...4,791,458 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19566775 NCBI chrNW_004624758:13,542,467...13,545,106
Ensembl chrNW_004624758:13,536,493...13,545,599 		JBrowse link
G Oprm1 opioid receptor mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16402083 NCBI chrNW_004624785:4,147,079...4,195,712
Ensembl chrNW_004624785:4,032,689...4,196,186 		JBrowse link
G Phb1 prohibitin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18504422 NCBI chrNW_004624795:5,556,728...5,565,969
Ensembl chrNW_004624795:5,556,450...5,565,988 		JBrowse link
G Pick1 protein interacting with PRKCA 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17606663 NCBI chrNW_004624752:9,880,773...9,895,270
Ensembl chrNW_004624752:9,880,670...9,895,230 		JBrowse link
G Rgs9 regulator of G protein signaling 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17318883 NCBI chrNW_004624870:3,138,311...3,249,297
Ensembl chrNW_004624870:3,143,950...3,218,117 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12931138 NCBI chrNW_004624751:694,165...720,287
Ensembl chrNW_004624751:694,099...719,465 		JBrowse link
G Snca synuclein alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:15542733 NCBI chrNW_004624757:17,393,046...17,528,783
Ensembl chrNW_004624757:17,392,998...17,528,320 		JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16807759 NCBI chrNW_004624855:3,260,800...3,271,864
Ensembl chrNW_004624855:3,260,809...3,271,367 		JBrowse link
alcohol-induced mental disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:26711020 NCBI chrNW_004624747:20,407,190...20,438,605
Ensembl chrNW_004624747:20,403,717...20,438,690 		JBrowse link
G Ankk1 ankyrin repeat and kinase domain containing 1 ISO DNA:SNP:exon:rs1800497(human) RGD PMID:18669994 RGD:401959336 NCBI chrNW_004624784:8,810,409...8,821,732
Ensembl chrNW_004624784:8,810,559...8,820,444 		JBrowse link
G Drd2 dopamine receptor D2 ISO DNA:SNP:cds:957C>T(human) RGD PMID:18669994 RGD:401959336 NCBI chrNW_004624784:8,828,589...8,906,617
Ensembl chrNW_004624784:8,827,006...8,865,529 		JBrowse link
G Foxo4 forkhead box O4 ISO protein:increased phosphorylation:small intestine: RGD PMID:23292333 RGD:10402360 NCBI chrNW_004624903:1,390,899...1,399,745
Ensembl chrNW_004624903:1,391,910...1,399,949 		JBrowse link
G Gsr glutathione-disulfide reductase treatment ISO RGD PMID:24972622 RGD:10401897 NCBI chrNW_004624780:13,440,269...13,497,435
Ensembl chrNW_004624780:13,440,235...13,496,535 		JBrowse link
G Hectd4 HECT domain E3 ubiquitin protein ligase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35713687 NCBI chrNW_004624747:19,843,434...20,031,188
Ensembl chrNW_004624747:19,843,720...20,029,225 		JBrowse link
alcohol-related birth defects term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank3 ankyrin 3 ISO DNA:SNP:CDS:rs7917190 RGD PMID:29109170 RGD:597830079 NCBI chrNW_004624791:3,299,287...3,633,631 JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor 10 ISO associated with cleft lip; DNA:SNP: :rs2294035, rs4876274 RGD PMID:31372216 RGD:597830081 NCBI chrNW_004624861:992,824...1,083,048
Ensembl chrNW_004624861:1,006,948...1,082,106 		JBrowse link
G Rps6ka1 ribosomal protein S6 kinase A1 ISO DNA:SNP:CDS:rs4659444 RGD PMID:29109170 RGD:597830079 NCBI chrNW_004624764:10,527,012...10,566,625
Ensembl chrNW_004624764:10,526,948...10,569,910 		JBrowse link
alcoholic psychosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr2a 5-hydroxytryptamine receptor 2A ISO DNA:SNP:promoter:-1438G>A RGD PMID:11842624 RGD:401900738 NCBI chrNW_004624748:8,154,288...8,223,226
Ensembl chrNW_004624748:8,155,107...8,223,259 		JBrowse link
drug psychosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin beta 2 ISO protein:increased expression:striatum RGD PMID:26174132 RGD:11534754 NCBI chrNW_004624786:8,568,102...8,576,445
Ensembl chrNW_004624786:8,568,198...8,577,914 		JBrowse link
G Drd2 dopamine receptor D2 ISO RGD PMID:26174132 RGD:11534754 NCBI chrNW_004624784:8,828,589...8,906,617
Ensembl chrNW_004624784:8,827,006...8,865,529 		JBrowse link
G Gad1 glutamate decarboxylase 1 susceptibility ISO protein:decreased expression:prefrontal cortex
associated with amphetamine abuse; DNA:haplotype: :rs769404���rs701492(human) 		RGD PMID:24200867 PMID:27967329 RGD:401900122 RGD:401900162 NCBI chrNW_004624787:8,308,759...8,345,929
Ensembl chrNW_004624787:8,308,759...8,347,686 		JBrowse link
G Gad2 glutamate decarboxylase 2 susceptibility ISO associated with amphetamine abuse; DNA:SNP: :rs2236418(human) RGD PMID:27967329 RGD:401900122 NCBI chrNW_004624796:2,700,443...2,771,757
Ensembl chrNW_004624796:2,703,614...2,771,555 		JBrowse link
G Oprm1 opioid receptor mu 1 ISO associated with amphetamine abuse;DNA:SNP:intron:IVS2+691G>C (human) RGD PMID:16402083 RGD:401827939 NCBI chrNW_004624785:4,147,079...4,195,712
Ensembl chrNW_004624785:4,032,689...4,196,186 		JBrowse link
fetal alcohol spectrum disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank3 ankyrin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29109170 NCBI chrNW_004624791:3,299,287...3,633,631 JBrowse link
G Apoe apolipoprotein E ISO RGD PMID:15007105 RGD:12904641 NCBI chrNW_004624907:1,752,322...1,755,308 JBrowse link
G Avp arginine vasopressin ISO mRNA:decreased expression:hypothalamic nucleus RGD PMID:15142835 RGD:596933086 NCBI chrNW_004624741:4,208,305...4,210,097
Ensembl chrNW_004624741:4,208,329...4,210,071 		JBrowse link
G Bpifa1 BPI fold containing family A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15513904 NCBI chrNW_004624842:6,024,460...6,031,718 JBrowse link
G C3 complement C3 ISO protein:increased activity:blood RGD PMID:30657461 RGD:408418720 NCBI chrNW_004624828:3,773,816...3,798,077
Ensembl chrNW_004624828:3,770,221...3,797,946 		JBrowse link
G Cat catalase ISO CTD Direct Evidence: therapeutic CTD PMID:26074427 NCBI chrNW_004624767:12,680,940...12,715,468
Ensembl chrNW_004624767:12,680,953...12,715,739 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 sexual_dimorphism ISO associated with chronic mild stress, age effect; mRNA:altered expression:hippocampus (rat) RGD PMID:29251811 RGD:401965484 NCBI chrNW_004624849:2,484,144...2,528,130
Ensembl chrNW_004624849:2,484,109...2,528,223 		JBrowse link
G Dio3 iodothyronine deiodinase 3 treatment ISO RGD PMID:23763370 RGD:13432044 NCBI chrNW_004624734:2,611,864...2,613,932 JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO mRNA,protein:increased expression:Pituitary gland (rat) RGD PMID:26509893 RGD:11344152 NCBI chrNW_004624828:2,316,042...2,358,866
Ensembl chrNW_004624828:2,315,251...2,358,711 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta ISO mRNA:increased expression:pituitary gland (rat) RGD PMID:26509893 RGD:11344152 NCBI chrNW_004624842:6,450,972...6,505,929
Ensembl chrNW_004624842:6,450,852...6,475,785 		JBrowse link
G Drd2 dopamine receptor D2 ISO DNA:Hypermethylation:promoter
mRNA:decreased expression: pituitary gland (rat) 		RGD PMID:26509893 PMID:28710248 RGD:11344152 RGD:401960105 NCBI chrNW_004624784:8,828,589...8,906,617
Ensembl chrNW_004624784:8,827,006...8,865,529 		JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 ISO mRNA:increased expression:pituitary gland (rat) RGD PMID:26509893 RGD:11344152 NCBI chrNW_004624754:24,354,271...24,368,319
Ensembl chrNW_004624754:24,354,284...24,368,638 		JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta3 treatment
sexual_dimorphism 		ISO in male mice only; mRNA:increased expression:frontal cortex: RGD PMID:23763370 PMID:30312858 RGD:13432044 RGD:405866345 NCBI chrNW_004624896:962,253...1,173,842
Ensembl chrNW_004624896:966,487...1,173,625 		JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma2 ISO mRNA:increased expression:posterior hypothalamic region (rat) RGD PMID:18514412 RGD:402528884 NCBI chrNW_004624733:27,506,827...27,593,750
Ensembl chrNW_004624733:27,504,660...27,594,039 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B treatment ISO RGD PMID:22037411 PMID:23763370 RGD:13210751 RGD:13432044 NCBI chrNW_004624752:24,008,520...24,480,834
Ensembl chrNW_004624752:24,135,487...24,459,288 		JBrowse link
G Hdac2 histone deacetylase 2 ISO mRNA,protein:increased expression:pituitary gland (rat) RGD PMID:26509893 RGD:11344152 NCBI chrNW_004624856:4,834,197...4,861,546
Ensembl chrNW_004624856:4,834,217...4,861,592 		JBrowse link
G Hdac4 histone deacetylase 4 ISO mRNA,protein:increased expression:pituitary gland (rat) RGD PMID:26509893 RGD:11344152 NCBI chrNW_004624847:3,846,196...4,101,537
Ensembl chrNW_004624847:3,845,858...4,101,487 		JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 ISO protein:increased expression:placenta (rat) RGD PMID:26342748 RGD:401965481 NCBI chrNW_004624746:18,883,587...18,889,205
Ensembl chrNW_004624746:18,883,353...18,889,402 		JBrowse link
G Igf1 insulin like growth factor 1 ISO mRNA:decreased expression:cerebellum (rat) RGD PMID:16909201 RGD:12904886 NCBI chrNW_004624750:5,881,065...5,954,799
Ensembl chrNW_004624750:5,881,091...5,952,300 		JBrowse link
G Igf1r insulin like growth factor 1 receptor ISO protein:decreased activity:cerebellum (rat) RGD PMID:16909201 RGD:12904886 NCBI chrNW_004624768:5,396,027...5,688,435
Ensembl chrNW_004624768:5,396,156...5,681,809 		JBrowse link
G Mat2a methionine adenosyltransferase 2A ISO mRNA:decreased expression:brain (rat) RGD PMID:26180184 RGD:11074449 NCBI chrNW_004624749:17,596,381...17,603,804
Ensembl chrNW_004624749:17,596,381...17,603,867 		JBrowse link
G Mecp2 methyl-CpG binding protein 2 treatment ISO mRNA:increased expression:pituitary gland (rat) RGD PMID:23763370 PMID:26509893 RGD:11344152 RGD:13432044 NCBI chrNW_004624946:620,581...685,339
Ensembl chrNW_004624946:628,284...685,246 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase ISO mRNA:decreased expression:brain (rat) RGD PMID:26180184 RGD:11074449 NCBI chrNW_004624775:13,791,690...13,903,888
Ensembl chrNW_004624775:13,792,043...13,896,559 		JBrowse link
G Nos1 nitric oxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25511929 NCBI chrNW_004624747:15,940,614...16,118,051
Ensembl chrNW_004624747:16,003,969...16,113,165 		JBrowse link
G Oprk1 opioid receptor kappa 1 ISO DNA, mRNA:hypomethylation, increased expression:ventral tegmental area, prefrontal cortex RGD PMID:29678771 RGD:401851055 NCBI chrNW_004624735:2,301,248...2,325,678
Ensembl chrNW_004624735:2,301,101...2,325,684 		JBrowse link
G Oprl1 opioid related nociceptin receptor 1 ISO mRNA:decreased expression:ventral tegmental area RGD PMID:29678771 RGD:401851055 NCBI chrNW_004624741:29,713,937...29,720,617
Ensembl chrNW_004624741:29,714,477...29,720,716 		JBrowse link
G Pdyn prodynorphin ISO DNA, mRNA:hypomethylation, altered expression:ventral tegmental area, nucleus accumbens RGD PMID:29678771 RGD:401851055 NCBI chrNW_004624741:3,239,101...3,253,507
Ensembl chrNW_004624741:3,237,942...3,253,503 		JBrowse link
G Per2 period circadian regulator 2 treatment ISO RGD PMID:31329297 RGD:405878078 NCBI chrNW_004624847:3,359,174...3,399,584
Ensembl chrNW_004624847:3,361,170...3,390,405 		JBrowse link
G Pnoc prepronociceptin ISO mRNA:increased expression:nucleus accumbens RGD PMID:29678771 RGD:401851055 NCBI chrNW_004624758:23,007,530...23,026,962
Ensembl chrNW_004624758:23,007,573...23,028,704 		JBrowse link
G Pomc proopiomelanocortin treatment ISO RGD PMID:31329297 RGD:405878078 NCBI chrNW_004624738:7,442,223...7,448,513
Ensembl chrNW_004624738:7,442,292...7,445,020 		JBrowse link
G Prl prolactin ISO mRNA,protein:increased expression:pituitary gland, blood plasma (rat)
mRNA, protein:increased expression:pituitary gland, blood plasma (rat) 		RGD PMID:26509893 PMID:28710248 RGD:11344152 RGD:401960105 NCBI chrNW_004624756:4,585,542...4,593,285 JBrowse link
G Pten phosphatase and tensin homolog ISO Protein:increased expression, increased activity:cerebellum (rat) RGD PMID:12700235 RGD:12801493 NCBI chrNW_004624791:13,975,235...14,056,900 JBrowse link
G Rasgrf1 Ras protein specific guanine nucleotide releasing factor 1 treatment ISO RGD PMID:23763370 RGD:13432044 NCBI chrNW_004624941:110,752...222,143
Ensembl chrNW_004624941:110,676...222,092 		JBrowse link
G Rps6ka1 ribosomal protein S6 kinase A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29109170 NCBI chrNW_004624764:10,527,012...10,566,625
Ensembl chrNW_004624764:10,526,948...10,569,910 		JBrowse link
G Setd7 SET domain containing 7, histone lysine methyltransferase ISO mRNA:decreased expression:pituitary gland (rat) RGD PMID:26509893 RGD:11344152 NCBI chrNW_004624777:19,764,383...19,812,804
Ensembl chrNW_004624777:19,768,698...19,814,506 		JBrowse link
G Slc25a12 solute carrier family 25 member 12 treatment ISO RGD PMID:23763370 RGD:13432044 NCBI chrNW_004624787:9,187,450...9,319,684
Ensembl chrNW_004624787:9,184,514...9,320,060 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 ISO mRNA:decreased expression:brain (rat) RGD PMID:26180184 RGD:11074449 NCBI chrNW_004624786:2,673,285...2,711,432
Ensembl chrNW_004624786:2,672,552...2,710,914 		JBrowse link
G Tlr4 toll like receptor 4 ameliorates ISO RGD PMID:30312858 RGD:405866345 NCBI chrNW_004624760:17,596,516...17,608,955
Ensembl chrNW_004624760:17,598,630...17,609,120 		JBrowse link
fetal alcohol syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rhoa ras homolog family member A ISO protein:increased activation:neuron, cerebellum RGD PMID:17109064 RGD:2298867 NCBI chrNW_004624730:3,316,122...3,361,820 JBrowse link
Postoperative Cognitive Dysfunction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end-product specific receptor ISO mRNA, protein:increased expression:hippocampus RGD PMID:23078219 RGD:597805826 NCBI chrNW_004624754:24,138,086...24,140,900 JBrowse link
G Agtr1 angiotensin II receptor type 1 ISO RGD PMID:24814703 RGD:10047100 NCBI chrNW_004624730:25,964,848...26,006,468
Ensembl chrNW_004624730:25,964,811...26,006,463 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 treatment ISO RGD PMID:30221701 RGD:597931096 NCBI chrNW_004624734:507,880...525,295
Ensembl chrNW_004624734:509,368...525,295 		JBrowse link
G App amyloid beta precursor protein treatment ISO protein:increased expression:plasma
protein:increased expression:hippocampus 		RGD PMID:30221701 PMID:33574912 PMID:35317728 RGD:597830151 RGD:597830178 RGD:597931096 NCBI chrNW_004624745:13,904,912...14,159,374
Ensembl chrNW_004624745:13,902,577...14,159,372 		JBrowse link
G Bace1 beta-secretase 1 treatment ISO RGD PMID:30221701 PMID:33574912 RGD:597830178 RGD:597931096 NCBI chrNW_004624784:12,725,419...12,759,530
Ensembl chrNW_004624784:12,725,063...12,759,637 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment ISO RGD PMID:33574912 RGD:597830178 NCBI chrNW_004624832:5,050,222...5,068,565
Ensembl chrNW_004624832:5,050,222...5,055,506 		JBrowse link
G Bcl2 BCL2 apoptosis regulator treatment ISO RGD PMID:33574912 RGD:597830178 NCBI chrNW_004624792:8,854,345...9,032,727
Ensembl chrNW_004624792:8,859,522...9,031,344 		JBrowse link
G Bdnf brain derived neurotrophic factor treatment ISO associated with brain ischemia RGD PMID:29065194 PMID:29571823 PMID:29599834 PMID:30232930 PMID:32564283 More... RGD:401959211 RGD:401965400 RGD:401976548 RGD:405850212 RGD:596933096 RGD:596936243 RGD:596936414 NCBI chrNW_004624766:17,281,882...17,330,601
Ensembl chrNW_004624766:17,279,630...17,330,490 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 treatment ISO protein:decreased phosphorylation:hippocampus RGD PMID:29571823 PMID:36688960 PMID:37736695 RGD:401959211 RGD:401959611 RGD:401960090 NCBI chrNW_004624765:8,374,160...8,436,969 JBrowse link
G Gdnf glial cell derived neurotrophic factor treatment ISO protein:decreased expression:hippocampus,urine
associated with rheumatic heart disease;protein:increased expression:serum
protein:altered expression:hippocampus, urine 		RGD PMID:25251457 PMID:28918204 PMID:29512789 PMID:33324197 PMID:34728231 More... RGD:401959611 RGD:405849389 RGD:405850212 RGD:405850250 RGD:405850251 RGD:405866364 NCBI chrNW_004624759:17,263,570...17,290,046
Ensembl chrNW_004624759:17,263,969...17,287,723 		JBrowse link
G Hmgb1 high mobility group box 1 ISO mRNA, protein:increased expression:hippocampus RGD PMID:23078219 RGD:597805826 NCBI chrNW_004624776:7,858,400...7,862,716
Ensembl chrNW_004624776:7,793,259...7,863,184 		JBrowse link
G Igf1 insulin like growth factor 1 treatment ISO mRNA:decreased expression:hippocampus
mRNA:decreased expression:plasma 		RGD PMID:33574912 PMID:35317728 RGD:597830151 RGD:597830178 NCBI chrNW_004624750:5,881,065...5,954,799
Ensembl chrNW_004624750:5,881,091...5,952,300 		JBrowse link
G Igfbp7 insulin like growth factor binding protein 7 ISO protein:increased expression:plasma (human) RGD PMID:25543030 RGD:401960875 NCBI chrNW_004624761:12,318,571...12,387,489
Ensembl chrNW_004624761:12,318,006...12,387,582 		JBrowse link
G Il1b interleukin 1 beta treatment ISO mRNA, protein:increased expression:hippocampus
protein:increased expression:hippocampus (rat) 		RGD PMID:22959208 PMID:23078219 PMID:29571823 PMID:30221701 PMID:33390808 RGD:401959211 RGD:401965467 RGD:597805826 RGD:597931096 RGD:7204702 NCBI chrNW_004624749:12,852,128...12,858,478
Ensembl chrNW_004624749:12,852,021...12,858,760 		JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO human protein in a rat model RGD PMID:23077050 RGD:8551854 NCBI chrNW_004624749:13,210,365...13,224,471
Ensembl chrNW_004624749:13,210,476...13,225,890 		JBrowse link
G Il6 interleukin 6 treatment ISO protein:increased expression:hippocampus (rat) RGD PMID:28684969 PMID:30221701 PMID:33390808 RGD:401965467 RGD:597538492 RGD:597931096 NCBI chrNW_004624739:7,957,709...7,963,414
Ensembl chrNW_004624739:7,957,674...7,962,318 		JBrowse link
G Ireb2 iron responsive element binding protein 2 ISO protein:increased expression:hippocampus (rat) RGD PMID:23229539 RGD:12904023 NCBI chrNW_004624894:2,446,014...2,498,650
Ensembl chrNW_004624894:2,445,704...2,499,009 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 treatment ISO protein:decreased phosphorylation:hippocampus RGD PMID:36688960 PMID:37736695 RGD:401959611 RGD:401960090 NCBI chrNW_004624747:1,296,062...1,389,674
Ensembl chrNW_004624747:1,296,221...1,389,757 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 treatment ISO protein:decreased phosphorylation:hippocampus RGD PMID:36688960 PMID:37736695 RGD:401959611 RGD:401960090 NCBI chrNW_004624782:13,150,824...13,158,327
Ensembl chrNW_004624782:13,152,039...13,159,113 		JBrowse link
G Ngf nerve growth factor treatment ISO associated with brain ischemia RGD PMID:29599834 PMID:30481505 PMID:34964700 RGD:401965395 RGD:401965400 RGD:401976548 NCBI chrNW_004624772:11,009,765...11,070,050
Ensembl chrNW_004624772:11,010,845...11,070,017 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3 group C member 1 treatment ISO associated with Traumatic Brain Injuries;mRNA:decreased expression:hippocampus, hypothalamus RGD PMID:28086911 PMID:36637480 RGD:408345237 RGD:408364984 NCBI chrNW_004624774:2,496,276...2,603,894
Ensembl chrNW_004624774:2,495,304...2,602,632 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 treatment ISO RGD PMID:29065194 PMID:30232930 PMID:32564283 RGD:596933096 RGD:596936243 RGD:596936414 NCBI chrNW_004624809:8,274,736...8,622,287
Ensembl chrNW_004624809:8,276,951...8,616,765 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta treatment ISO RGD PMID:30221701 RGD:597931096 NCBI chrNW_004624730:15,226,786...15,399,097
Ensembl chrNW_004624730:15,226,379...15,355,857 		JBrowse link
G Tlr2 toll like receptor 2 treatment ISO RGD PMID:28684969 PMID:32300366 RGD:597538486 RGD:597538492 NCBI chrNW_004624858:4,931,820...4,984,175
Ensembl chrNW_004624858:4,979,485...4,981,833 		JBrowse link
G Tlr4 toll like receptor 4 treatment ISO RGD PMID:28684969 PMID:32300366 RGD:597538486 RGD:597538492 NCBI chrNW_004624760:17,596,516...17,608,955
Ensembl chrNW_004624760:17,598,630...17,609,120 		JBrowse link
G Tnf tumor necrosis factor treatment ISO mRNA, protein:increased expression:hippocampus
protein:increased expression:hippocampus (rat) 		RGD PMID:23078219 PMID:29571823 PMID:33390808 RGD:401959211 RGD:401965467 RGD:597805826 NCBI chrNW_004624754:24,623,059...24,625,647
Ensembl chrNW_004624754:24,623,425...24,625,531 		JBrowse link
subacute delirium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase (Cartwright blood group) disease_progression ISO RGD PMID:8043620 RGD:405855847 NCBI chrNW_004624740:16,275,108...16,280,639
Ensembl chrNW_004624740:16,275,117...16,281,793 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISO mRNA, protein:increased expression:hippocampal formation, amygdala RGD PMID:27760517 RGD:405850209 NCBI chrNW_004624815:5,817,196...5,821,197
Ensembl chrNW_004624815:5,816,601...5,820,864 		JBrowse link
G Tph2 tryptophan hydroxylase 2 ISO mRNA:increased expression:hippocampus, prefrontal cortex RGD PMID:36750928 RGD:597805905 NCBI chrNW_004624750:25,702,597...25,801,938
Ensembl chrNW_004624750:25,702,630...25,801,618 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14234
    Chemically-Induced Disorders 1179
      substance-related disorder 653
        substance-induced psychosis 90
          alcohol-induced mental disorder + 46
          drug-induced mental disorder + 5
          subacute delirium + 29
Path 2
Term Annotations click to browse term
  disease 14234
    disease of anatomical entity 13936
      nervous system disease 12272
        central nervous system disease 11004
          brain disease 10320
            disease of mental health 7412
              cognitive disorder 1964
                psychotic disorder 1045
                  substance-induced psychosis 90
                    alcohol-induced mental disorder + 46
                    drug-induced mental disorder + 5
                    subacute delirium + 29
paths to the root