RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: chronic fatigue syndrome
Accession: DOID:8544
browse the term
Definition: A syndrome that involves prolonged and severe tiredness or weariness that is unrelated to exertion, is not relieved by rest and for a minimum of six months and is not directly caused by other conditions. (DO)
Synonyms: exact_synonym: CFS; Chronic Fatigue Disorder; Chronic Fatigue Fibromyalgia Syndrome; Chronic Fatigue Syndromes; Infectious Mononucleosis Like Syndrome, Chronic; Myalgic Encephalomyelitis; chronic fatigue and immune dysfunction syndrome; chronic fatigue disorders; chronic fatigue-fibromyalgia syndromes; myalgic encephalitis; myalgic encephalomyelitis/chronic fatigue syndrome; postviral fatigue syndrome; postviral fatigue syndromes; royal free disease
xref: EFO:0004540 ; GARD:7121 ; ICD10CM:G93.32 ; ICD10CM:R53.82 ; ICD9CM:780.71 ; MESH:D015673 ; MONDO:0005404 ; NCI:C3037 ; ORDO:1983
For additional species annotation, visit the
Alliance of Genome Resources .
G
Ccl24
C-C motif chemokine ligand 24
ISO
protein:increased expression:plasma:
RGD
PMID:26615570
RGD:11538286
NCBI chr12:26,737,423...26,741,420
Ensembl chr12:21,100,835...21,104,893
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Cd28
Cd28 molecule
ISO
RGD
PMID:18801465
RGD:5131614
NCBI chr 9:69,660,316...69,689,192
Ensembl chr 9:62,166,192...62,194,685
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Cx3cl1
C-X3-C motif chemokine ligand 1
ISO
protein:decreased expression:plasma:
RGD
PMID:26615570
RGD:11538286
NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,227,340...10,236,833
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Cxcl9
C-X-C motif chemokine ligand 9
ISO
protein:decreased expression:plasma:
RGD
PMID:26615570
RGD:11538286
NCBI chr14:16,007,166...16,012,077
Ensembl chr14:15,722,908...15,728,435
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Disc1
DISC1 scaffold protein
susceptibility
ISO
DNA:SNP:Cds:p.S704C(human)
RGD
PMID:20227423
RGD:5509831
NCBI chr19:69,911,548...70,120,970
Ensembl chr19:53,014,616...53,219,778
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Il16
interleukin 16
ISO
protein:decreased expression:plasma:
RGD
PMID:26615570
RGD:11538286
NCBI chr 1:147,026,852...147,127,177
Ensembl chr 1:137,617,944...137,718,130
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Prf1
perforin 1
ISO
RGD
PMID:21619669
RGD:6482801
NCBI chr20:29,789,040...29,794,550
Ensembl chr20:29,246,202...29,251,701
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Ren
renin
ISO
associated with Postural Orthostatic Tachycardia Syndrome; protein:increased activity:plasma (human)
RGD
PMID:21906029
RGD:6892702
NCBI chr13:47,348,312...47,359,539
Ensembl chr13:44,796,091...44,807,489
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RT1-Ba
RT1 class II, locus Ba
susceptibility
ISO
DNA:polymorphism (human) DNA:polymorphism: :HLA-DQA1*01 (human)
RGD
PMID:16049290 PMID:16049290
RGD:5147827 , RGD:5147827
NCBI chr20:4,577,057...4,581,650
Ensembl chr20:4,575,134...4,579,744
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Serpinf1
serpin family F member 1
ISO
protein:increased expression:cerebrospinal fluid (human)
RGD
PMID:16321154
RGD:28867246
NCBI chr10:60,748,504...60,760,898
Ensembl chr10:60,249,708...60,262,646
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Slc6a4
solute carrier family 6 member 4
severity
ISO
DNA:repeats:promoter: protein:decreased expression:rostral anterior cingulate cortex (human) DNA:repeats, haplotype:promoter:
RGD
PMID:14592408 PMID:15570154 PMID:26473596
RGD:36947383 , RGD:38500210 , RGD:11098915
NCBI chr10:62,322,688...62,357,060
Ensembl chr10:61,826,123...61,858,384
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Trpc6
transient receptor potential cation channel, subfamily C, member 6
ISO
DNA:SNPs: :
RGD
PMID:27834303
RGD:40886272
NCBI chr 8:14,044,216...14,148,808
Ensembl chr 8:5,758,935...5,828,092
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Vegfa
vascular endothelial growth factor A
ISO
protein:decreased expression:plasma:
RGD
PMID:26615570
RGD:11538286
NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641
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