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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:actinomycosis
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Accession:DOID:8478 term browser browse the term
Definition:A commensal bacterial infectious disease that results in infection, which is characterized by contiguous spread, suppurative and granulomatous inflammation, and formation of multiple abscesses and sinus tracts that may discharge sulfur granules, has_material_basis_in Actinomyces israelii, has_material_basis_in Actinomyces gerencseriae, has_material_basis_in Actinomyces naeslundii, has_material_basis_in Actinomyces odontolyticus, has_material_basis_in Actinomyces viscosus, has_material_basis_in Actinomyces meyeri, has_material_basis_in Propionibacterium propionicum, which require a break in the integrity of the mucous membranes and the presence of devitalized tissue to invade deeper body structures. (DO)
Synonyms:exact_synonym: Actinomyces Infection;   Actinomyces Infections;   Actinomycoses;   Madura foot due to Actinomadura;   actinomycotic infection;   actinomycotic madura foot;   actinomycotic mycetema;   actinomycotic mycetoma of foot
 related_synonym: actinomycetoma;   boil
 primary_id: MESH:D000196
 xref: EFO:0007128;   GARD:5728;   ICD10CM:A42;   ICD9CM:039.9;   NCI:C34350
For additional species annotation, visit the Alliance of Genome Resources.


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Whipple disease term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd163 CD163 molecule ISO protein:increased expression:duodenum, macrophage (human) RGD PMID:19664628 RGD:149735573 NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19099
    disease of anatomical entity 18440
      respiratory system disease 5241
        actinomycosis 1
          Aerobic Actinomyces Infection 0
          Cervicofacial Actinomycosis 0
          Whipple disease + 1
Path 2
Term Annotations click to browse term
  disease 19099
    disease by infectious agent 2253
      Bacterial Infections and Mycoses 1119
        bacterial infectious disease 825
          Gram-Positive Bacterial Infections 395
            Actinomycetales Infections 320
              actinomycosis 1
                Aerobic Actinomyces Infection 0
                Cervicofacial Actinomycosis 0
                Whipple disease + 1
paths to the root