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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:rheumatoid arthritis
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Accession:DOID:7148 term browser browse the term
Definition:An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint. (DO)
Synonyms:exact_synonym: RA;   atrophic arthritis;   rheumatic arthritis or polyarthritis
 narrow_synonym: ACPA-negative rheumatoid arthritis;   ACPA-positive rheumatoid arthritis;   RHEUMATOID ARTHRITIS, PROGRESSION OF;   rheumatoid arthritis, susceptibility to
 primary_id: MESH:D001172
 alt_id: OMIM:180300
 xref: EFO:0000685;   EFO:0009459;   EFO:0009460;   ICD10CM:M06.9;   ICD9CM:714.0;   NCI:C2884
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
rheumatoid arthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin ISO GAD PMID:15118671 RGD:1331525 NCBI chr 6:121,612,920...121,656,197
Ensembl chr 6:121,612,335...121,656,186 		JBrowse link
G Abcb1a ATP-binding cassette, sub-family B member 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:20080907 PMID:22104130 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179 		JBrowse link
G Abcc3 ATP-binding cassette, sub-family C member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823 		JBrowse link
G Abcc4 ATP-binding cassette, sub-family C member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr14:118,720,104...118,945,475
Ensembl chr14:118,720,104...118,943,631 		JBrowse link
G Abcc5 ATP-binding cassette, sub-family C member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr16:20,150,053...20,245,178
Ensembl chr16:20,150,053...20,245,144 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661 		JBrowse link
G Acan aggrecan disease_progression ISO CTD Direct Evidence: marker/mechanism
protein:increased degradation:cartilage		 CTD
RGD		 PMID:15292528 PMID:16507130 RGD:11570537 NCBI chr 7:78,702,974...78,764,847
Ensembl chr 7:78,703,231...78,764,847 		JBrowse link
G Ackr3 atypical chemokine receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 1:90,131,702...90,143,446
Ensembl chr 1:90,131,702...90,144,473 		JBrowse link
G Adamts4 ADAM metallopeptidase with thrombospondin type 1 motif 4 ISO mRNA:increased expression:synovium RGD PMID:11801682 RGD:10043106 NCBI chr 1:171,077,698...171,089,836
Ensembl chr 1:171,077,990...171,088,206 		JBrowse link
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif 5 ISO protein:alternative form:synovium RGD PMID:11801682 RGD:10043106 NCBI chr16:85,655,045...85,698,013
Ensembl chr16:85,653,061...85,698,716 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:12833524 PMID:21789720 RGD:5686424 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778 		JBrowse link
G Adora2a adenosine A2a receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr10:75,152,711...75,170,626
Ensembl chr10:75,152,711...75,170,618 		JBrowse link
G Adrb3 adrenergic receptor, beta 3 ISO DNA:missense mutation:cds:p.W64R rs4994 (human) RGD PMID:12739037 RGD:5684893 NCBI chr 8:27,715,804...27,720,833
Ensembl chr 8:27,715,804...27,740,644 		JBrowse link
G Aff3 AF4/FMR2 family, member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr 1:38,212,936...38,704,036
Ensembl chr 1:38,216,407...38,704,036 		JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO protein:decreased expression:plasma (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16385501 PMID:20541603 RGD:7244141 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910 		JBrowse link
G Ahr aryl-hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:18617548 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139 		JBrowse link
G Ang angiogenin, ribonuclease, RNase A family, 5 ISO RGD PMID:12653852 RGD:6892721 NCBI chr14:51,328,607...51,339,462
Ensembl chr14:51,328,607...51,339,466 		JBrowse link
G Ankrd55 ankyrin repeat domain 55 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr13:112,424,985...112,523,391
Ensembl chr13:112,424,985...112,520,536 		JBrowse link
G Anxa3 annexin A3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr 5:96,941,244...96,993,827
Ensembl chr 5:96,941,198...96,993,825 		JBrowse link
G Apoa4 apolipoprotein A-IV ISO protein:increased expression:blood serum (human) RGD PMID:20367977 RGD:5685646 NCBI chr 9:46,152,142...46,154,756
Ensembl chr 9:46,151,994...46,154,757 		JBrowse link
G Arid5b AT-rich interaction domain 5B ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 PMID:23143596 NCBI chr10:67,928,353...68,114,596
Ensembl chr10:67,928,350...68,114,570 		JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19193698 NCBI chr 1:71,596,315...71,618,562
Ensembl chr 1:71,596,309...71,618,790 		JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc ISO mRNA:decreased expression:liver RGD PMID:18372237 RGD:153352318 NCBI chr 5:137,979,783...137,988,495
Ensembl chr 5:137,979,782...137,988,495 		JBrowse link
G B3gnt2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr11:22,784,739...22,810,336
Ensembl chr11:22,709,738...22,810,961 		JBrowse link
G B3gnt9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr 8:105,979,270...105,981,895
Ensembl chr 8:105,979,270...105,981,785 		JBrowse link
G Baiap2l1 BAI1-associated protein 2-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 5:144,201,335...144,294,922
Ensembl chr 5:144,201,336...144,294,922 		JBrowse link
G Bcl2a1b B cell leukemia/lymphoma 2 related protein A1b ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 9:89,081,326...89,089,891
Ensembl chr 9:89,081,262...89,089,880 		JBrowse link
G Bdkrb2 bradykinin receptor, beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr12:105,529,431...105,561,503
Ensembl chr12:105,529,485...105,561,496 		JBrowse link
G Bglap bone gamma carboxyglutamate protein ISO protein:increased expression:serum RGD PMID:22447331 PMID:3488088 RGD:6483593, RGD:6483600 NCBI chr 3:88,290,802...88,291,773
Ensembl chr 3:88,290,808...88,291,771 		JBrowse link
G Bgn biglycan ISO CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chr  X:72,527,207...72,539,542
Ensembl chr  X:72,527,208...72,539,539 		JBrowse link
G Blk B lymphoid kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr14:63,610,286...63,654,636
Ensembl chr14:63,610,285...63,654,486 		JBrowse link
G Bmp4 bone morphogenetic protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126 		JBrowse link
G Bmp6 bone morphogenetic protein 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr13:38,529,098...38,684,283
Ensembl chr13:38,529,083...38,684,278 		JBrowse link
G Btnl2 butyrophilin-like 2 susceptibility ISO DNA:SNPs: : RGD PMID:23364395 RGD:9685033 NCBI chr17:34,573,763...34,588,466
Ensembl chr17:34,573,796...34,588,469 		JBrowse link
G C3 complement component 3 ISO RGD PMID:7561187 RGD:11040775 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G C4b complement C4B (Chido blood group) ISO RGD PMID:22076784 RGD:5688263 NCBI chr17:34,947,249...34,962,876
Ensembl chr17:34,947,354...34,962,856 		JBrowse link
G Cald1 caldesmon 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chr 6:34,575,433...34,752,404
Ensembl chr 6:34,575,435...34,752,408 		JBrowse link
G Casp7 caspase 7 ISO RGD PMID:18785314 RGD:5684540 NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776 		JBrowse link
G Cast calpastatin ISO RGD PMID:7706496 RGD:5683620 NCBI chr13:74,840,485...74,956,993
Ensembl chr13:74,840,487...74,956,929 		JBrowse link
G Cat catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22450443 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Cav2 caveolin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr 6:17,281,184...17,289,129
Ensembl chr 6:17,281,184...17,289,114 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 ISO protein:increased expression:serum RGD PMID:20056091 RGD:4891442 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Ccl21a C-C motif chemokine ligand 21 (serine) ISO CTD Direct Evidence: marker/mechanism CTD PMID:18794853 PMID:20453842 PMID:23143596 NCBI chr 4:42,772,860...42,773,991
Ensembl chr 4:42,772,860...42,773,993 		JBrowse link
G Ccl22 C-C motif chemokine ligand 22 ISO protein:increased expression:plasma: RGD PMID:19942450 RGD:10054497 NCBI chr 8:95,472,312...95,478,016
Ensembl chr 8:95,472,218...95,478,327 		JBrowse link
G Ccl8 C-C motif chemokine ligand 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr11:82,006,011...82,007,625
Ensembl chr11:82,006,011...82,007,625 		JBrowse link
G Ccn1 cellular communication network factor 1 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:blood serum (human)		 CTD
RGD		 PMID:19192274 PMID:34031328 RGD:329845561 NCBI chr 3:145,352,726...145,355,740
Ensembl chr 3:145,352,731...145,355,736 		JBrowse link
G Ccn2 cellular communication network factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 ISO RGD PMID:12860725 RGD:5688170 NCBI chr 9:123,762,163...123,768,729
Ensembl chr 9:123,762,161...123,768,729 		JBrowse link
G Ccr3 C-C motif chemokine receptor 3 ISO protein:increased expression:synovial fluid, neutrophil RGD PMID:19017998 RGD:4145632 NCBI chr 9:123,817,799...123,831,729
Ensembl chr 9:123,822,009...123,831,726 		JBrowse link
G Ccr4 C-C motif chemokine receptor 4 ISO protein:increased expression:synovial membrane:
mRNA:increased expression:synovium:		 RGD PMID:19942450 PMID:25430645 RGD:10054497, RGD:10054499 NCBI chr 9:114,319,384...114,334,544
Ensembl chr 9:114,319,384...114,333,984 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 resistance
no_association		 ISO DNA:frameshift mutation:cds:p.S185_T195del rs333 (human) RGD PMID:16541097 PMID:17565662 RGD:1626290, RGD:1626283 NCBI chr 9:123,921,557...123,934,153
Ensembl chr 9:123,921,580...123,947,736 		JBrowse link
G Ccr6 C-C motif chemokine receptor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453841 PMID:20453842 PMID:23143596 NCBI chr17:8,454,875...8,477,353
Ensembl chr17:8,454,875...8,475,973 		JBrowse link
G Cd2 CD2 antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 3:101,183,224...101,195,255
Ensembl chr 3:101,183,215...101,195,255 		JBrowse link
G Cd244a CD244 molecule A susceptibility ISO ClinVar Annotator: match by term: Rheumatoid arthritis
CTD Direct Evidence: marker/mechanism		 ClinVar
OMIM
CTD		 PMID:18794858 NCBI chr 1:171,386,287...171,412,884
Ensembl chr 1:171,386,761...171,437,314 		JBrowse link
G Cd28 CD28 antigen ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19898481 PMID:20453842 PMID:23143596 PMID:19075187 RGD:5131619 NCBI chr 1:60,785,547...60,812,521
Ensembl chr 1:60,755,959...60,812,518 		JBrowse link
G Cd3e CD3 antigen, epsilon polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr 9:44,910,033...44,920,961
Ensembl chr 9:44,910,038...44,920,925 		JBrowse link
G Cd40 CD40 antigen ISO DNA:SNP: :rs4810485 (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:18794853 PMID:20453842 PMID:23143596 PMID:20498205 RGD:5490972 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868 		JBrowse link
G Cd5 CD5 antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr19:10,695,471...10,716,390
Ensembl chr19:10,694,480...10,716,366 		JBrowse link
G Cd80 CD80 antigen ISO protein:increased expression:serum RGD PMID:22917707 RGD:6893647 NCBI chr16:38,277,793...38,316,682
Ensembl chr16:38,275,923...38,316,697 		JBrowse link
G Cd83 CD83 antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr13:43,938,588...43,956,609
Ensembl chr13:43,938,251...43,956,608 		JBrowse link
G Cdk6 cyclin dependent kinase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18794853 NCBI chr 5:3,391,004...3,581,008
Ensembl chr 5:3,391,485...3,581,008 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta ISO protein:increased expression:knee, articular cartilage (human) RGD PMID:19248099 RGD:10401213 NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338 		JBrowse link
G Chi3l1 chitinase 3 like 1 severity ISO protein:increased secretion:serum (human) RGD PMID:10461474 RGD:4892605 NCBI chr 1:134,109,894...134,117,769
Ensembl chr 1:134,109,914...134,117,919 		JBrowse link
G Chrna7 cholinergic receptor, nicotinic, alpha polypeptide 7 ISO mRNA,protein:increased expression:joint, spleen: RGD PMID:31279484 RGD:151676715 NCBI chr 7:62,748,440...62,862,274
Ensembl chr 7:62,748,440...62,862,317 		JBrowse link
G Chrng cholinergic receptor, nicotinic, gamma polypeptide ISO ClinVar Annotator: match by term: Rheumatoid arthritis ClinVar PMID:23261301 PMID:25741868 NCBI chr 1:87,133,533...87,139,365
Ensembl chr 1:87,132,379...87,140,416 		JBrowse link
G Ciita class II transactivator susceptibility
no_association		 ISO DNA:haplotype:promoter/CDS:rs3087456G/rs4774C (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Rheumatoid arthritis
DNA:polymorphism:promoter:-168A>G (human)
DNA:polymorphism:promoter:rs3087456, no association in a German cohort (Human)		 OMIM
CTD
ClinVar
RGD		 PMID:15821736 PMID:16849401 PMID:25741868 PMID:28492532 PMID:19221398 More... RGD:5491176, RGD:1358146, RGD:5491189 NCBI chr16:10,297,877...10,348,928
Ensembl chr16:10,297,923...10,346,282 		JBrowse link
G Clec12a C-type lectin domain family 12, member a ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 6:129,327,207...129,342,266
Ensembl chr 6:129,319,654...129,342,266 		JBrowse link
G Clec16a C-type lectin domain family 16, member A ISO DNA:polymorphism:intron:rs6498169G (human) RGD PMID:19221398 RGD:5491176 NCBI chr16:10,363,173...10,562,742
Ensembl chr16:10,363,203...10,562,742 		JBrowse link
G Col2a1 collagen, type II, alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27028940 PMID:29935983 NCBI chr15:97,873,483...97,902,525
Ensembl chr15:97,873,483...97,902,576 		JBrowse link
G Cp ceruloplasmin ISO CTD Direct Evidence: marker/mechanism CTD PMID:26001728 NCBI chr 3:20,011,097...20,063,914
Ensembl chr 3:20,011,218...20,063,309 		JBrowse link
G Crp C-reactive protein, pentraxin-related ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:1568518 PMID:22173958 PMID:22173958 RGD:6904209, RGD:6904209 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598 		JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991 		JBrowse link
G Ctsd cathepsin D ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr 7:141,929,647...141,941,564
Ensembl chr 7:141,929,648...141,941,775 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 ISO RGD PMID:11465708 RGD:4892002 NCBI chr 8:95,498,808...95,509,055
Ensembl chr 8:95,498,637...95,509,055 		JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 PMID:19192274 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797 		JBrowse link
G Cxcl5 C-X-C motif chemokine ligand 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chr 5:90,907,157...90,909,484
Ensembl chr 5:90,907,219...90,909,483 		JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 ISO protein:increased expression:synovial fluid, neutrophil RGD PMID:19017998 RGD:4145632 NCBI chr  X:100,775,141...100,777,753
Ensembl chr  X:100,775,141...100,777,875 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030 		JBrowse link
G Cybb cytochrome b-245, beta polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:24313545 NCBI chr  X:9,301,493...9,354,005
Ensembl chr  X:9,301,491...9,354,010 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr10:59,785,497...59,787,592
Ensembl chr10:59,785,491...59,787,656 		JBrowse link
G Ddx6 DEAD-box helicase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 9:44,514,113...44,552,028
Ensembl chr 9:44,516,189...44,552,028 		JBrowse link
G Dhfr dihydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr13:92,491,291...92,525,561
Ensembl chr13:92,491,234...92,525,561 		JBrowse link
G Dnase1l3 deoxyribonuclease 1-like 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 PMID:30224649 NCBI chr14:14,475,014...14,504,586
Ensembl chr14:14,475,200...14,505,240 		JBrowse link
G Dnase2a deoxyribonuclease II alpha IAGP OMIM:180300 MouseDO NCBI chr 8:85,635,384...85,638,332
Ensembl chr 8:85,635,189...85,649,544 		JBrowse link
G Dnmt1 DNA methyltransferase 1 severity ISO mRNA:increased expression:mononuclear cell RGD PMID:20937307 RGD:9588623 NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184 		JBrowse link
G Dnmt3b DNA methyltransferase 3B disease_progression ISO DNA:polymorphism:promoter:-283C>T(human) RGD PMID:19777235 RGD:9589110 NCBI chr 2:153,491,332...153,529,650
Ensembl chr 2:153,491,370...153,529,650 		JBrowse link
G Edn1 endothelin 1 treatment ISO RGD PMID:22249931 RGD:8661695 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466 		JBrowse link
G Eln elastin ISO RGD PMID:12643515 RGD:9585739 NCBI chr 5:134,731,449...134,776,300
Ensembl chr 5:134,731,447...134,776,177 		JBrowse link
G Eno1 enolase 1, alpha non-neuron ISO CTD Direct Evidence: marker/mechanism CTD PMID:19898480 NCBI chr 4:150,321,165...150,333,336
Ensembl chr 4:150,321,178...150,333,336 		JBrowse link
G Epas1 endothelial PAS domain protein 1 ISO protein:increased expression:layer of synovial tissue, stromal cell RGD PMID:12823854 RGD:10395366 NCBI chr17:87,061,292...87,140,838
Ensembl chr17:87,061,128...87,140,838 		JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 ISO mRNA:increased expression:peripheral blood mononuclear cell RGD PMID:36104638 RGD:155791669 NCBI chr14:66,056,476...66,071,418
Ensembl chr14:66,056,487...66,071,443 		JBrowse link
G Esr2 estrogen receptor 2 (beta) severity ISO DNA:SNP:exon:rs1256049(human) RGD PMID:21523342 RGD:5508794 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033 		JBrowse link
G F2 coagulation factor II ISO CTD Direct Evidence: marker/mechanism CTD PMID:26001728 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759 		JBrowse link
G Fas Fas cell surface death receptor susceptibility ISO DNA:snp:promoter:g.-670A>G (human)
protein:increased expression:serum (human)		 RGD PMID:23053964 PMID:20875116 PMID:12148596 RGD:8662433, RGD:12903969, RGD:8662455 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Fasl Fas ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064 		JBrowse link
G Fcgr1 Fc receptor, IgG, high affinity I ISO protein:increased expression:synovial joint: RGD PMID:16670289 RGD:9685708 NCBI chr 3:96,190,225...96,201,285
Ensembl chr 3:96,190,225...96,201,285 		JBrowse link
G Fcgr4 Fc receptor, IgG, low affinity IV susceptibility ISO DNA:polymorphism:exon:p.F158V(rs396991)(human)
DNA:CNVs
protein:decreased expression:NK cell		 RGD PMID:19019892 PMID:25154742 PMID:15334114 RGD:5508391, RGD:11344974, RGD:5508467 NCBI chr 1:170,846,495...170,857,330
Ensembl chr 1:170,846,489...170,857,330 		JBrowse link
G Fkbp5 FK506 binding protein 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr17:28,617,727...28,705,123
Ensembl chr17:28,618,068...28,736,501 		JBrowse link
G Foxo3 forkhead box O3 ISO mRNA,protein:increased expression:peripheral blood mononuclear cell, polymorphonuclear cell,synovium: RGD PMID:19435720 RGD:10402186 NCBI chr10:42,057,841...42,152,691
Ensembl chr10:42,057,837...42,152,751 		JBrowse link
G Foxp3 forkhead box P3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20476861 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Fpgs folylpolyglutamyl synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr 2:32,572,621...32,594,208
Ensembl chr 2:32,572,621...32,594,157 		JBrowse link
G Gart phosphoribosylglycinamide formyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr16:91,418,283...91,444,505
Ensembl chr16:91,418,074...91,443,840 		JBrowse link
G Gata3 GATA binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 2:9,861,889...9,894,845
Ensembl chr 2:9,861,889...9,894,845 		JBrowse link
G Gc vitamin D binding protein ISO protein:decreased expression:plasma
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:3874814 PMID:9548303 RGD:5509931 NCBI chr 5:89,565,370...89,605,757
Ensembl chr 5:89,565,381...89,605,757 		JBrowse link
G Gdf5 growth differentiation factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18830904 NCBI chr 2:155,782,943...155,787,204
Ensembl chr 2:155,782,943...155,787,287 		JBrowse link
G Ggh gamma-glutamyl hydrolase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr 4:20,041,963...20,066,111
Ensembl chr 4:20,042,052...20,066,750 		JBrowse link
G Gin1 gypsy retrotransposon integrase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 1:97,697,894...97,721,435
Ensembl chr 1:97,697,897...97,721,434 		JBrowse link
G Gprc5a G protein-coupled receptor, family C, group 5, member A ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr 6:135,042,660...135,061,707
Ensembl chr 6:135,042,649...135,061,707 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 IAGP
ISO		 DNA: deletion: : heterozygous
protein: decreased expression: mononuclear cells
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:10094932 PMID:18662895 PMID:10094932 RGD:5688373, RGD:5688380 NCBI chr19:4,336,027...4,356,350
Ensembl chr19:4,336,029...4,356,250 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 no_association IAGP
ISO		 DNA: deletion::GRK2 and GRK6 deletions resulted in more severe arthritis
protein: decreased expression: mononuclear leukocytes		 RGD PMID:18662895 PMID:10094932 RGD:5688373, RGD:5688380 NCBI chr19:60,877,995...61,084,406
Ensembl chr19:60,878,187...61,084,406 		JBrowse link
G Grk6 G protein-coupled receptor kinase 6 IAGP
ISO		 DNA: deletion: : homozygous
CTD Direct Evidence: marker/mechanism
protein: decreased expression: mononuclear cells		 CTD
RGD		 PMID:10094932 PMID:18662895 PMID:10094932 RGD:5688373, RGD:5688380 NCBI chr13:55,592,865...55,608,740
Ensembl chr13:55,592,885...55,608,740 		JBrowse link
G Gsdme gasdermin E ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr 6:50,167,013...50,240,837
Ensembl chr 6:50,165,868...50,240,842 		JBrowse link
G Gstm1 glutathione S-transferase, mu 1 susceptibility ISO DNA:deletion: :
DNA:deletion: : 		RGD PMID:16887863 PMID:16870093 PMID:15940757 RGD:5490993, RGD:5490994, RGD:5490998 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289 		JBrowse link
G Gstt1 glutathione S-transferase, theta 1 severity
susceptibility		 ISO DNA:deletion: : RGD PMID:19473562 PMID:20401725 PMID:20597111 RGD:5490553, RGD:5490983, RGD:5490982 NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418 		JBrowse link
G H2-Aa histocompatibility 2, class II antigen A, alpha ISO DNA:polymorphisms
DNA:polymorphism (human)		 RGD PMID:11482129 PMID:11454644 RGD:5147859, RGD:5147860 NCBI chr17:34,501,718...34,506,797
Ensembl chr17:34,501,718...34,506,797 		JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 ISO DNA:polymorphism (human) RGD PMID:11454644 RGD:5147860 NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393 		JBrowse link
G H2-Eb1 histocompatibility 2, class II antigen E beta susceptibility ISO DNA:polymorphisms: :multiple (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism (human)
DNA:polymorphisms (human)		 CTD
RGD		 PMID:19898480 PMID:20453842 PMID:22286218 PMID:21246357 PMID:11454644 More... RGD:5147567, RGD:5147860, RGD:5147616 NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648 		JBrowse link
G Hapln1 hyaluronan and proteoglycan link protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr13:89,688,654...89,759,951
Ensembl chr13:89,687,915...89,759,771 		JBrowse link
G Hcls1 hematopoietic cell specific Lyn substrate 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr16:36,755,345...36,783,576
Ensembl chr16:36,755,345...36,783,574 		JBrowse link
G Hdac1 histone deacetylase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32289289 NCBI chr 4:129,409,897...129,436,516
Ensembl chr 4:129,409,897...129,436,506 		JBrowse link
G Hfe homeostatic iron regulator ISO DNA:missense mutation: :p.C282Y (rs1800562) (human) RGD PMID:30651232 RGD:14746965 NCBI chr13:23,886,017...23,894,837
Ensembl chr13:23,886,017...23,894,837 		JBrowse link
G Hgf hepatocyte growth factor disease_progression ISO protein:increased expression:serum: RGD PMID:24387171 RGD:8548659 NCBI chr 5:16,758,493...16,827,448
Ensembl chr 5:16,758,493...16,825,150 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit ISO protein:increased expression:layer of synovial tissue, stromal cell RGD PMID:12823854 RGD:10395366 NCBI chr12:73,948,098...73,994,328
Ensembl chr12:73,948,149...73,994,304 		JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 severity ISO RGD PMID:18025202 RGD:9685481 NCBI chr 6:51,437,414...51,448,054
Ensembl chr 6:51,437,912...51,446,874 		JBrowse link
G Hoxd10 homeobox D10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 2:74,514,617...74,525,450
Ensembl chr 2:74,522,268...74,525,449 		JBrowse link
G Hoxd11 homeobox D11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 2:74,509,902...74,517,360
Ensembl chr 2:74,509,901...74,517,360 		JBrowse link
G Hoxd13 homeobox D13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 2:74,498,569...74,501,947
Ensembl chr 2:74,498,654...74,501,943 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 1:192,903,948...192,946,353
Ensembl chr 1:192,903,942...192,946,383 		JBrowse link
G Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 ISO mRNA:increased expression:peripheral blood leukocyte: RGD PMID:21417552 RGD:10402843 NCBI chr12:110,657,470...110,662,829
Ensembl chr12:110,657,039...110,669,162 		JBrowse link
G Hspa4 heat shock protein 4 ISO protein:increased expression:peripheral blood lymphocyte (human) RGD PMID:22047640 RGD:5688784 NCBI chr11:53,150,641...53,191,306
Ensembl chr11:53,150,641...53,191,284 		JBrowse link
G Hspa5 heat shock protein 5 ISO protein:increased expression:synovial joint RGD PMID:11315915 RGD:5685639 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559 		JBrowse link
G Hspa9 heat shock protein 9 ISO protein:increased expression:synovial cell: RGD PMID:23739258 RGD:10402561 NCBI chr18:35,070,467...35,087,404
Ensembl chr18:35,070,467...35,087,410 		JBrowse link
G Hspb1 heat shock protein 1 ISO protein:increased expression:serum: RGD PMID:21417552 RGD:10402843 NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417 		JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) ISO mRNA:increased expression:peripheral blood leukocyte: RGD PMID:21417552 RGD:10402843 NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402 		JBrowse link
G Ifng interferon gamma treatment ISO mRNA:increased expression:synovial (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:22450443 PMID:1417133 PMID:22660635 RGD:8157623, RGD:155663483 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Igf2 insulin-like growth factor 2 ISO DNA:loss of imprinting:synovial cell
protein:decreased expression:plasma		 RGD PMID:19556211 PMID:11247331 RGD:5510001, RGD:5510014 NCBI chr 7:142,204,505...142,220,566
Ensembl chr 7:142,204,503...142,220,553 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr11:7,156,086...7,165,498
Ensembl chr11:7,156,086...7,163,923 		JBrowse link
G Ikzf3 IKAROS family zinc finger 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr11:98,355,436...98,437,157
Ensembl chr11:98,355,728...98,436,857 		JBrowse link
G Il10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: RHEUMATOID ARTHRITIS, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Rheumatoid arthritis, progression of		 CTD
OMIM
ClinVar		 PMID:12847677 PMID:22450443 PMID:25741868 PMID:28492532 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il13 interleukin 13 ISO protein:increased expression:serum RGD PMID:12051401 RGD:8549582 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529 		JBrowse link
G Il17a interleukin 17A treatment ISO mRNA:increased expression:synovial (human) RGD PMID:20926833 PMID:22660635 RGD:9068415, RGD:155663483 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720 		JBrowse link
G Il18 interleukin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16368150 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140 		JBrowse link
G Il19 interleukin 19 ISO ClinVar Annotator: match by term: RHEUMATOID ARTHRITIS, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Rheumatoid arthritis, progression of ClinVar PMID:12847677 PMID:25741868 PMID:28492532 NCBI chr 1:130,860,393...130,873,194
Ensembl chr 1:130,860,393...130,867,852 		JBrowse link
G Il1a interleukin 1 alpha severity ISO associated with lung disease, interstitial
protein:increased expression:plasma, synovial fluid		 RGD PMID:11192540 PMID:8162643 RGD:4142818, RGD:7794716 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892 		JBrowse link
G Il1b interleukin 1 beta ISO protein:decreased expression:serum
mRNA:increased expression:synovial (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:12566094 PMID:17379860 PMID:22450443 PMID:22414257 PMID:22660635 RGD:6482656, RGD:155663483 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO
IMP		 CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:7706905 PMID:19192274 PMID:19447938 PMID:10637275 RGD:7174696, RGD:8549810 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506 		JBrowse link
G Il2 interleukin 2 ISO RGD PMID:6421522 RGD:8662948 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108 		JBrowse link
G Il20 interleukin 20 ISO RGD PMID:16947773 RGD:5147395 NCBI chr 1:130,834,722...130,839,033
Ensembl chr 1:130,834,722...130,839,188 		JBrowse link
G Il21r interleukin 21 receptor IMP RGD PMID:19342640 RGD:6892964 NCBI chr 7:125,202,424...125,232,742
Ensembl chr 7:125,202,601...125,232,742 		JBrowse link
G Il23a interleukin 23, alpha subunit p19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621 		JBrowse link
G Il23r interleukin 23 receptor susceptibility ISO DNA:SNP::rs1343151(human) RGD PMID:18647855 RGD:8549596 NCBI chr 6:67,399,906...67,468,838
Ensembl chr 6:67,399,916...67,468,839 		JBrowse link
G Il2ra interleukin 2 receptor, alpha chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:20476861 PMID:23143596 NCBI chr 2:11,647,603...11,698,005
Ensembl chr 2:11,647,618...11,698,004 		JBrowse link
G Il2rb interleukin 2 receptor, beta chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr15:78,363,456...78,396,569
Ensembl chr15:78,363,456...78,379,471 		JBrowse link
G Il3 interleukin 3 ISO DNA: SNPs: Multiple: gene-gene interaction RGD PMID:20018070 RGD:5686905 NCBI chr11:54,155,911...54,158,105
Ensembl chr11:54,156,129...54,158,103 		JBrowse link
G Il4ra interleukin 4 receptor, alpha severity ISO DNA:SNP: :rs1805010 (human) RGD PMID:24782180 RGD:10402783 NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646 		JBrowse link
G Il5 interleukin 5 ISO RGD PMID:22293286 RGD:5687156 NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933 		JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 PMID:22450443 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Il6ra interleukin 6 receptor, alpha ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:16729287 PMID:23143596 NCBI chr 3:89,776,631...89,820,503
Ensembl chr 3:89,771,366...89,820,503 		JBrowse link
G Il6st interleukin 6 signal transducer ISO
IAGP		 CTD Direct Evidence: marker/mechanism
OMIM:180300		 CTD
MouseDO		 PMID:20453842 NCBI chr13:112,600,604...112,643,394
Ensembl chr13:112,600,604...112,646,620 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr  X:73,057,520...73,067,527
Ensembl chr  X:73,057,520...73,067,524 		JBrowse link
G Irf5 interferon regulatory factor 5 ISO ClinVar Annotator: match by term: Rheumatoid arthritis
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
RGD		 PMID:15657875 PMID:16642019 PMID:17599733 PMID:18063667 PMID:20453842 More... RGD:40924627, RGD:40924559 NCBI chr 6:29,526,129...29,541,874
Ensembl chr 6:29,526,624...29,541,870 		JBrowse link
G Irf8 interferon regulatory factor 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 8:121,463,097...121,483,433
Ensembl chr 8:121,463,097...121,483,433 		JBrowse link
G Itga6 integrin alpha 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr 2:71,617,236...71,688,761
Ensembl chr 2:71,575,960...71,688,760 		JBrowse link
G Itpa inosine triphosphatase (nucleoside triphosphate pyrophosphatase) treatment ISO DNA:SNP: :94C>A(human) RGD PMID:29441893 RGD:14975307 NCBI chr 2:130,506,702...130,523,534
Ensembl chr 2:130,509,530...130,523,534 		JBrowse link
G Jak2 Janus kinase 2 IMP RGD PMID:21510883 RGD:6483024 NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480 		JBrowse link
G Kat2b K(lysine) acetyltransferase 2B ISO mRNA:increased expression:peripheral blood mononuclear cell RGD PMID:36104638 RGD:155791669 NCBI chr17:53,873,802...53,979,749
Ensembl chr17:53,873,889...53,979,748 		JBrowse link
G Kif5a kinesin family member 5A susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:snps:intron, 3' utr:c.2756-43A>C, c.*776C>T (rs775246, rs775251) (human)
DNA:snp:intron:c.1717-152C>G (rs1678542) (human)		 CTD
RGD		 PMID:23143596 PMID:21784728 PMID:23378462 RGD:12793073, RGD:12793072 NCBI chr10:127,061,564...127,102,217
Ensembl chr10:127,061,565...127,099,217 		JBrowse link
G Kmt2c lysine (K)-specific methyltransferase 2C treatment ISO RGD PMID:33914205 RGD:151356764 NCBI chr 5:25,476,793...25,703,853
Ensembl chr 5:25,476,796...25,703,781 		JBrowse link
G Lcn2 lipocalin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7554268 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264 		JBrowse link
G Lhx2 LIM homeobox protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 2:38,229,226...38,259,749
Ensembl chr 2:38,229,293...38,259,745 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 ISO RGD PMID:17082220 RGD:5508419 NCBI chr15:91,556,994...91,700,327
Ensembl chr15:91,557,378...91,700,323 		JBrowse link
G Ly96 lymphocyte antigen 96 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr 1:16,758,680...16,779,829
Ensembl chr 1:16,758,275...16,779,835 		JBrowse link
G Mab21l2 mab-21-like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 3:86,453,357...86,455,590
Ensembl chr 3:86,452,888...86,455,590 		JBrowse link
G Malat1 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) ISO mRNA:increased expression:cartilage tissue (human) RGD PMID:31472145 RGD:152177908 NCBI chr19:5,845,718...5,852,700
Ensembl chr19:5,845,717...5,852,706 		JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr10:37,009,239...37,014,922
Ensembl chr10:37,009,371...37,014,916 		JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 ISO mRNA:increased expression:mononuclear cell RGD PMID:20937307 RGD:9588623 NCBI chr18:70,701,298...70,761,769
Ensembl chr18:70,701,260...70,759,202 		JBrowse link
G Mbd4 methyl-CpG binding domain protein 4 susceptibility
no_association		 ISO DNA:snps:introns:IVS5-140A>G (rs3138355), IVS6-218C>T (rs2005618) (human)
DNA:snps:cds, intron:p.E346K, IVS6-218C>T (rs140693, rs2005618) (human)		 RGD PMID:20676650 PMID:22505706 RGD:9588977, RGD:9588978 NCBI chr 6:115,817,658...115,830,361
Ensembl chr 6:115,817,658...115,830,332 		JBrowse link
G Mdk midkine IAGP RGD PMID:15146411 RGD:1581200 NCBI chr 2:91,760,149...91,762,348
Ensembl chr 2:91,760,150...91,762,642 		JBrowse link
G Mgarp mitochondria localized glutamic acid rich protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 3:51,295,833...51,303,968
Ensembl chr 3:51,295,833...51,304,159 		JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) ISO CTD Direct Evidence: marker/mechanism CTD PMID:16872482 NCBI chr10:75,695,187...75,696,111
Ensembl chr10:75,695,187...75,696,074 		JBrowse link
G Mir146 microRNA 146 ISO mRNA:decreased expression:cartilage tissue (human)
mRNA:increased expression:synovial (human)		 RGD PMID:31472145 PMID:22660635 RGD:152177908, RGD:155663483 NCBI chr11:43,265,224...43,265,288
Ensembl chr11:43,265,224...43,265,288 		JBrowse link
G Mir23b microRNA 23b ISO mRNA, protein:decreased expression:synovial (human) RGD PMID:22660635 RGD:155663483 NCBI chr13:63,448,298...63,448,371
Ensembl chr13:63,448,298...63,448,371 		JBrowse link
G Mmel1 membrane metallo-endopeptidase-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 4:154,954,042...154,979,987
Ensembl chr 4:154,954,042...154,979,985 		JBrowse link
G Mmp10 matrix metallopeptidase 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 9:7,502,343...7,510,243
Ensembl chr 9:7,502,353...7,510,241 		JBrowse link
G Mmp12 matrix metallopeptidase 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 9:7,344,397...7,360,461
Ensembl chr 9:7,344,381...7,369,499 		JBrowse link
G Mmp14 matrix metallopeptidase 14 (membrane-inserted) IAGP OMIM:180300 MouseDO NCBI chr14:54,669,055...54,679,913
Ensembl chr14:54,669,069...54,682,821 		JBrowse link
G Mmp1a matrix metallopeptidase 1a (interstitial collagenase) ISO protein:increased expression:plasma (human) RGD PMID:9972954 RGD:7207129 NCBI chr 9:7,464,141...7,476,870
Ensembl chr 9:7,464,141...7,476,857 		JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) ISO protein:increased expression:plasma (human) RGD PMID:9972954 RGD:7207129 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047 		JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16872482 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048 		JBrowse link
G Mmp3 matrix metallopeptidase 3 disease_progression ISO protein:increased expression:serum (human) RGD PMID:7639798 PMID:22314025 PMID:11796404 RGD:7207128, RGD:8693673, RGD:7241254 NCBI chr 9:7,445,822...7,455,975
Ensembl chr 9:7,445,822...7,455,975 		JBrowse link
G Mmp8 matrix metallopeptidase 8 ISO protein:increased expression:synovial fluid, serum (human) RGD PMID:15194590 RGD:7207131 NCBI chr 9:7,558,430...7,568,487
Ensembl chr 9:7,558,457...7,568,486 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO RGD PMID:16406300 RGD:1582623 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770 		JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22450443 PMID:26001728 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239 		JBrowse link
G mt-Nd1 NADH dehydrogenase 1, mitochondrial ISO DNA:missense mutations:cds:multiple (human) RGD PMID:15987486 RGD:5490238 NCBI chr MT:2,751...3,707
Ensembl chr MT:2,751...3,707 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO DNA:SNP: :677C>T(human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:22104130 PMID:23685257 RGD:7387222 NCBI chr 4:148,123,534...148,144,019
Ensembl chr 4:148,123,534...148,144,008 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 induced ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphism:M153T (rat)		 CTD
RGD		 PMID:12833524 PMID:28135245 PMID:21275845 RGD:41404729 NCBI chr 5:134,248,907...134,258,479
Ensembl chr 5:134,248,907...134,258,479 		JBrowse link
G Ncf2 neutrophil cytosolic factor 2 ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphism, SNP:cds (rs789181) (human)		 CTD
RGD		 PMID:12833524 PMID:17897462 RGD:41404710 NCBI chr 1:152,675,904...152,712,741
Ensembl chr 1:152,675,945...152,712,742 		JBrowse link
G Ncf4 neutrophil cytosolic factor 4 ISO DNA:polymorphism, SNP:cds (rs729749) (human) RGD PMID:17897462 RGD:41404710 NCBI chr15:78,128,324...78,146,782
Ensembl chr15:78,129,001...78,146,780 		JBrowse link
G Ndufa4l2 Ndufa4, mitochondrial complex associated like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr10:127,345,143...127,353,023
Ensembl chr10:127,350,836...127,353,023 		JBrowse link
G Nfkbie nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr17:45,866,626...45,874,095
Ensembl chr17:45,866,629...45,874,095 		JBrowse link
G Nfkbil1 nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1 susceptibility ISO ClinVar Annotator: match by term: Rheumatoid arthritis
CTD Direct Evidence: marker/mechanism
DNA:snp:promoter:c.-132T>A (rs2071592) (human)		 ClinVar
CTD
OMIM
RGD		 PMID:12509789 PMID:12509789 RGD:1331681 NCBI chr17:35,439,151...35,455,457
Ensembl chr17:35,439,151...35,454,768 		JBrowse link
G Notch4 notch 4 ISO mRNA : increased expression: : cd4+ cells RGD PMID:20132067 RGD:6480790 NCBI chr17:34,783,257...34,807,517
Ensembl chr17:34,783,242...34,807,477 		JBrowse link
G Npsr1 neuropeptide S receptor 1 ISO RGD PMID:20179762 RGD:4891930 NCBI chr 9:24,009,212...24,229,151
Ensembl chr 9:24,009,292...24,227,694 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 ISO mRNA:increased expression:paw RGD PMID:18448865 RGD:4892311 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 4:48,045,098...48,086,446
Ensembl chr 4:48,045,153...48,086,447 		JBrowse link
G Oprm1 opioid receptor, mu 1 susceptibility ISO DNA:missense mutation:exon:p.N40D (118A>G) (rs 1799971) (human) RGD PMID:31309790 RGD:401827955 NCBI chr10:6,708,593...6,988,209
Ensembl chr10:6,708,506...6,988,198 		JBrowse link
G Padi2 peptidyl arginine deiminase, type II ISO ClinVar Annotator: match by term: Rheumatoid arthritis ClinVar NCBI chr 4:140,633,648...140,679,897
Ensembl chr 4:140,633,655...140,679,897 		JBrowse link
G Padi4 peptidyl arginine deiminase, type IV ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Rheumatoid arthritis		 CTD
ClinVar		 PMID:23143596 NCBI chr 4:140,472,819...140,501,514
Ensembl chr 4:140,473,176...140,501,547 		JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide ISO RGD PMID:1708827 RGD:6482653 NCBI chr15:79,880,066...79,899,178
Ensembl chr15:79,880,075...79,899,178 		JBrowse link
G Pgf placental growth factor ISO RGD PMID:19180491 RGD:6483591 NCBI chr12:85,213,411...85,224,559
Ensembl chr12:85,213,409...85,224,564 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO mRNA:increased expression:cartilage tissue (human) RGD PMID:31472145 RGD:152177908 NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725 		JBrowse link
G Pla2g7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) ISO RGD PMID:17326817 RGD:6482776 NCBI chr17:43,878,885...43,923,093
Ensembl chr17:43,878,989...43,923,092 		JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO RGD PMID:22011479 RGD:6484117 NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393 		JBrowse link
G Plb1 phospholipase B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24520335 NCBI chr 5:32,390,035...32,521,700
Ensembl chr 5:32,390,052...32,523,864 		JBrowse link
G Pld4 phospholipase D family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr12:112,727,089...112,735,420
Ensembl chr12:112,727,089...112,735,424 		JBrowse link
G Plek pleckstrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr11:16,921,206...16,958,718
Ensembl chr11:16,921,206...17,002,381 		JBrowse link
G Pon1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16055108 NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946 		JBrowse link
G Pou3f1 POU domain, class 3, transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 4:124,551,439...124,554,448
Ensembl chr 4:124,550,600...124,554,448 		JBrowse link
G Prdm1 PR domain containing 1, with ZNF domain ISO CTD Direct Evidence: marker/mechanism CTD PMID:19898481 PMID:20453842 PMID:23143596 PMID:36181686 NCBI chr10:44,313,170...44,404,579
Ensembl chr10:44,313,173...44,404,497 		JBrowse link
G Prkcq protein kinase C, theta ISO CTD Direct Evidence: marker/mechanism CTD PMID:18794853 PMID:20453842 PMID:23143596 NCBI chr 2:11,176,922...11,306,033
Ensembl chr 2:11,176,919...11,306,033 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15167967 NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:11978490 PMID:19192274 PMID:21905970 RGD:5508313 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Ptk2 PTK2 protein tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr15:73,076,951...73,297,192
Ensembl chr15:73,076,951...73,295,129 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr18:67,798,571...67,857,697
Ensembl chr18:67,798,581...67,857,665 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) susceptibility
no_association		 ISO DNA:snp:cds:p.R620W (rs2476601) (human)
ClinVar Annotator: match by term: RHEUMATOID ARTHRITIS, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Rheumatoid arthritis
CTD Direct Evidence: marker/mechanism
DNA:SNP::1858C>T (human)
DNA:snp:cds:p.R263Q (rs33996649) (human)		 ClinVar
OMIM
CTD
RGD		 PMID:15004560 PMID:15208781 PMID:15273934 PMID:15580548 PMID:15719322 More... RGD:6484535, RGD:7829746, RGD:6484595 NCBI chr 3:103,763,891...103,819,568
Ensembl chr 3:103,767,111...103,819,563 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr 1:137,990,597...138,103,491
Ensembl chr 1:137,990,599...138,103,446 		JBrowse link
G Pxk PX domain containing serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 NCBI chr14:14,304,656...14,371,593
Ensembl chr14:14,304,656...14,371,562 		JBrowse link
G Rab8a RAB8A, member RAS oncogene family ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr 8:72,915,044...72,935,210
Ensembl chr 8:72,915,044...72,937,748 		JBrowse link
G Rap2a RAS related protein 2a ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr14:120,715,873...120,744,606
Ensembl chr14:120,715,856...120,744,606 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 2:117,110,464...117,173,358
Ensembl chr 2:117,110,474...117,173,482 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr 5:53,713,121...53,814,787
Ensembl chr 5:53,623,494...53,814,704 		JBrowse link
G Rcan1 regulator of calcineurin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr16:92,188,839...92,263,057
Ensembl chr16:92,188,841...92,267,755 		JBrowse link
G Rel reticuloendotheliosis oncogene ISO CTD Direct Evidence: marker/mechanism CTD PMID:19503088 PMID:20453842 PMID:23143596 NCBI chr11:23,686,847...23,720,969
Ensembl chr11:23,686,847...23,720,970 		JBrowse link
G Rgmb repulsive guidance molecule family member B ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr17:16,024,923...16,051,508
Ensembl chr17:16,023,450...16,051,301 		JBrowse link
G Runx1 runt related transcription factor 1 no_association ISO DNA:SNPs: :rs2242720, rs4816502 (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs2268277 (human)
DNA:SNP:intron:24658G>C (human)		 CTD
RGD		 PMID:23143596 PMID:20018071 PMID:18087673 PMID:18328148 PMID:16821265 RGD:6482836, RGD:6482840, RGD:6482839, RGD:6482837 NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037 		JBrowse link
G Runx2 runt related transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr17:44,806,873...45,125,518
Ensembl chr17:44,806,874...45,125,684 		JBrowse link
G Sema3c sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C ISO protein:increased expression:knee, synovium (human) RGD PMID:15077297 RGD:1580084 NCBI chr 5:17,779,814...17,935,266
Ensembl chr 5:17,779,279...17,935,266 		JBrowse link
G Slc11a1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 severity ISO DNA:polymorphism:promoter (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphisms, deletion: :823C>T, p.D543N (human)		 CTD
RGD		 PMID:16597321 PMID:12135431 PMID:10719815 RGD:5684967, RGD:5684971 NCBI chr 1:74,414,318...74,429,974
Ensembl chr 1:74,414,354...74,425,221 		JBrowse link
G Slc22a4 solute carrier family 22 (organic cation transporter), member 4 susceptibility ISO ClinVar Annotator: match by term: Rheumatoid arthritis
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:14608356 NCBI chr11:53,873,941...53,920,866
Ensembl chr11:53,873,949...53,918,916 		JBrowse link
G Slc25a12 solute carrier family 25 (mitochondrial carrier, Aralar), member 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr 2:71,104,614...71,198,125
Ensembl chr 2:71,101,407...71,198,093 		JBrowse link
G Sms spermine synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr  X:156,226,847...156,275,283
Ensembl chr  X:156,226,851...156,275,283 		JBrowse link
G Snhg14 small nucleolar RNA host gene 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34529319 NCBI chr 7:58,922,485...60,099,925 JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 PMID:15292528 PMID:24313545 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:15761492 RGD:1581382 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916 		JBrowse link
G Spred2 sprouty-related EVH1 domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr11:19,874,442...19,974,026
Ensembl chr11:19,874,375...19,974,026 		JBrowse link
G St6galnac5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 PMID:17568789 NCBI chr 3:152,525,522...152,687,847
Ensembl chr 3:152,522,718...152,687,883 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO associated with T-cell large granular lymphocyte leukemia RGD PMID:22591296 RGD:6892936 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr 1:52,026,265...52,146,348
Ensembl chr 1:52,026,307...52,146,348 		JBrowse link
G Sts steroid sulfatase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr  X:168,856,332...169,015,037 JBrowse link
G Supt20 SPT20 SAGA complex component ISO ClinVar Annotator: match by term: Rheumatoid arthritis ClinVar NCBI chr 3:54,600,181...54,636,184
Ensembl chr 3:54,600,228...54,636,187 		JBrowse link
G Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 ISO mRNA, protein:increased expression:synovial (human) RGD PMID:22660635 RGD:155663483 NCBI chr10:7,781,412...7,832,039
Ensembl chr10:7,781,417...7,831,994 		JBrowse link
G Tab3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 ISO mRNA, protein:increased expression:synovial (human) RGD PMID:22660635 RGD:155663483 NCBI chr  X:84,617,466...84,678,075
Ensembl chr  X:84,617,628...84,678,075 		JBrowse link
G Tagap T cell activation Rho GTPase activating protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr17:8,144,832...8,153,729
Ensembl chr17:8,144,832...8,153,729 		JBrowse link
G Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) ISO RGD PMID:9645419 RGD:6482275 NCBI chr17:34,423,453...34,435,295
Ensembl chr17:34,422,501...34,435,295 		JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15292528 PMID:17379860 NCBI chr 6:3,962,589...3,988,977
Ensembl chr 6:3,962,595...3,988,919 		JBrowse link
G Thbd thrombomodulin ISO RGD PMID:15700117 RGD:5685020 NCBI chr 2:148,246,391...148,250,108
Ensembl chr 2:148,246,386...148,250,108 		JBrowse link
G Tle3 transducin-like enhancer of split 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 9:61,279,608...61,325,779
Ensembl chr 9:61,279,648...61,325,779 		JBrowse link
G Tlr1 toll-like receptor 1 ISO ClinVar Annotator: match by term: Rheumatoid arthritis ClinVar PMID:32594150 NCBI chr 5:65,082,023...65,090,945
Ensembl chr 5:65,082,022...65,090,906 		JBrowse link
G Tlr2 toll-like receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074 		JBrowse link
G Tmpo thymopoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr10:90,983,433...91,017,614
Ensembl chr10:90,983,433...91,017,177 		JBrowse link
G Tnf tumor necrosis factor treatment
no_association		 ISO
IAGP		 mRNA:increased expression:synovial (human)
CTD Direct Evidence: marker/mechanism|therapeutic
OMIM:180300
DNA:SNP:promoter:-238G>A, -308G>A (human)
DNA:SNP:promoter:-857C>T (human)		 CTD
MouseDO
RGD		 PMID:2001072 PMID:8391952 PMID:12566094 PMID:22450443 PMID:34459104 More... RGD:10450537, RGD:155663483, RGD:12904065, RGD:12904065 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tnfaip2 tumor necrosis factor, alpha-induced protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr12:111,408,898...111,421,452
Ensembl chr12:111,408,903...111,421,452 		JBrowse link
G Tnfaip3 tumor necrosis factor, alpha-induced protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18794853 PMID:20453842 PMID:21841782 PMID:23143596 PMID:30224649 NCBI chr10:18,876,658...18,891,158
Ensembl chr10:18,876,658...18,891,405 		JBrowse link
G Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) ISO CTD Direct Evidence: therapeutic CTD PMID:23333834 NCBI chr15:54,114,014...54,141,700
Ensembl chr15:54,114,015...54,141,880 		JBrowse link
G Tnfrsf14 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 NCBI chr 4:155,002,944...155,013,077
Ensembl chr 4:155,006,390...155,013,020 		JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a treatment ISO DNA:SNP:promoter:36G>A (human) RGD PMID:25311255 RGD:12904065 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447 		JBrowse link
G Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr17:57,496,437...57,501,182
Ensembl chr17:57,496,492...57,501,177 		JBrowse link
G Traf1 TNF receptor-associated factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18794853 PMID:23143596 NCBI chr 2:34,831,762...34,851,784
Ensembl chr 2:34,831,762...34,851,784 		JBrowse link
G Traf6 TNF receptor-associated factor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr 2:101,508,765...101,532,013
Ensembl chr 2:101,508,774...101,532,014 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 treatment ISO RGD PMID:27049384 RGD:127229930 NCBI chr17:48,539,763...48,553,955
Ensembl chr17:48,539,796...48,553,952 		JBrowse link
G Txndc5 thioredoxin domain containing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23326410 NCBI chr13:38,684,242...38,712,800
Ensembl chr13:38,684,055...38,712,800 		JBrowse link
G Txnip thioredoxin interacting protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 3:96,465,273...96,469,173
Ensembl chr 3:96,465,273...96,469,199 		JBrowse link
G Tyk2 tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 PMID:30224649 NCBI chr 9:21,015,364...21,042,689
Ensembl chr 9:21,015,364...21,042,539 		JBrowse link
G Tyms thymidylate synthase treatment ISO DNA:polymorphism: : RGD PMID:22763757 RGD:11075093 NCBI chr 5:30,243,544...30,279,261
Ensembl chr 5:30,263,200...30,278,615 		JBrowse link
G Tyrobp TYRO protein tyrosine kinase binding protein treatment ISO RGD PMID:27049384 RGD:127229930 NCBI chr 7:30,113,207...30,117,007
Ensembl chr 7:30,113,185...30,117,010 		JBrowse link
G Vdr vitamin D (1,25-dihydroxyvitamin D3) receptor no_association ISO DNA:SNP:exon:rs2228570 (human)
DNA:SNP: :rs1544410 (human)		 RGD PMID:21820934 PMID:21820934 RGD:8158077, RGD:8158077 NCBI chr15:97,752,308...97,806,177
Ensembl chr15:97,752,306...97,808,511 		JBrowse link
G Vegfa vascular endothelial growth factor A disease_progression ISO protein:increased expression:serum:
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16368150 PMID:24387171 RGD:8548659 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
G Vim vimentin ISO RGD PMID:21792832 RGD:6480508 NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637 		JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase IAGP OMIM:180300 MouseDO NCBI chr 1:36,800,879...36,821,902
Ensembl chr 1:36,800,879...36,821,899 		JBrowse link
G Zfp36 zinc finger protein 36 IAGP OMIM:180300 MouseDO NCBI chr 7:28,076,208...28,078,680
Ensembl chr 7:28,076,209...28,079,678 		JBrowse link
adult-onset Still's disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hgf hepatocyte growth factor ISO protein:increased expression:serum: RGD PMID:24387171 RGD:8548659 NCBI chr 5:16,758,493...16,827,448
Ensembl chr 5:16,758,493...16,825,150 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO protein:increased expression:serum: RGD PMID:24387171 RGD:8548659 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
Juvenile Pauciarticular Chronic Arthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G H2-Eb1 histocompatibility 2, class II antigen E beta susceptibility ISO DNA:polymorphism: :HLA-DRB1*1104, HLA-DRB1*080(human) RGD PMID:7955632 RGD:7365102 NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648 		JBrowse link
juvenile rheumatoid arthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 1700019D03Rik RIKEN cDNA 1700019D03 gene ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:52,961,483...53,031,816
Ensembl chr 1:52,961,483...53,059,338 		JBrowse link
G Acp3 acid phosphatase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:104,165,439...104,214,921
Ensembl chr 9:104,165,450...104,214,947 		JBrowse link
G Acrbp proacrosin binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:125,026,890...125,040,228
Ensembl chr 6:125,026,652...125,040,230 		JBrowse link
G Adcy7 adenylate cyclase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:88,998,818...89,056,593
Ensembl chr 8:88,999,031...89,056,590 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:70,132,283...70,146,206
Ensembl chr11:70,132,283...70,146,179 		JBrowse link
G Ankrd9 ankyrin repeat domain 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:110,942,854...110,945,516
Ensembl chr12:110,941,787...110,945,474 		JBrowse link
G Aopep aminopeptidase O ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:63,112,707...63,473,910
Ensembl chr13:63,112,707...63,473,910 		JBrowse link
G Aqp9 aquaporin 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:71,017,941...71,075,170
Ensembl chr 9:71,017,941...71,075,964 		JBrowse link
G Areg amphiregulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:91,287,458...91,296,291
Ensembl chr 5:91,287,458...91,296,291 		JBrowse link
G Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:63,958,704...64,254,922
Ensembl chr15:63,958,706...64,254,768 		JBrowse link
G Avl9 AVL9 cell migration associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:56,691,720...56,738,897
Ensembl chr 6:56,691,884...56,738,897 		JBrowse link
G B4galt5 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:167,140,364...167,191,155
Ensembl chr 2:167,140,364...167,191,103 		JBrowse link
G Bend2 BEN domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr  X:160,080,852...160,124,208
Ensembl chr  X:160,070,452...160,149,248 		JBrowse link
G Bltp3b bridge-like lipid transfer protein family member 3B ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:89,580,830...89,655,753
Ensembl chr10:89,580,853...89,655,733 		JBrowse link
G Btg1 BTG anti-proliferation factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:96,452,863...96,458,675
Ensembl chr10:96,452,868...96,458,671 		JBrowse link
G Btg3 BTG anti-proliferation factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr16:78,156,748...78,174,069
Ensembl chr16:78,129,525...78,174,080 		JBrowse link
G C8b complement component 8, beta polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:7980680 NCBI chr 4:104,623,514...104,661,745
Ensembl chr 4:104,623,514...104,661,745 		JBrowse link
G C9orf72 C9orf72, member of C9orf72-SMCR8 complex ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:35,191,285...35,226,153
Ensembl chr 4:35,191,285...35,226,175 		JBrowse link
G Cald1 caldesmon 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:34,575,433...34,752,404
Ensembl chr 6:34,575,435...34,752,408 		JBrowse link
G Camsap1 calmodulin regulated spectrin-associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:25,816,850...25,873,574
Ensembl chr 2:25,816,850...25,873,294 		JBrowse link
G Ccdc122 coiled-coil domain containing 122 ISO ClinVar Annotator: match by term: JUVENILE ARTHRITIS ClinVar PMID:25741868 NCBI chr14:77,274,212...77,349,703
Ensembl chr14:77,274,212...77,349,697 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 no_association ISO DNA:frameshift mutation:cds:p.S185_T195del rs333 (human)
DNA:polymorphisms: :multiple (human)		 RGD PMID:17565662 PMID:16775617 RGD:1626283, RGD:1626284 NCBI chr 9:123,921,557...123,934,153
Ensembl chr 9:123,921,580...123,947,736 		JBrowse link
G Cd14 CD14 antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851 		JBrowse link
G Cd83 CD83 antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:43,938,588...43,956,609
Ensembl chr13:43,938,251...43,956,608 		JBrowse link
G Cd8b1 CD8 subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:71,299,772...71,314,476
Ensembl chr 6:71,299,772...71,314,478 		JBrowse link
G Ciita class II transactivator susceptibility
no_association		 ISO DNA:polymorphism:exon:1614G>C (human)
DNA:polymorphism:promoter:rs3087456, no association in a German cohort (Human)		 RGD PMID:17661914 PMID:16426246 RGD:5491187, RGD:5491189 NCBI chr16:10,297,877...10,348,928
Ensembl chr16:10,297,923...10,346,282 		JBrowse link
G Clu clusterin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:66,205,932...66,218,997
Ensembl chr14:66,205,932...66,218,996 		JBrowse link
G Cmtm2b CKLF-like MARVEL transmembrane domain containing 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:105,048,838...105,057,396
Ensembl chr 8:105,048,862...105,057,396 		JBrowse link
G Crem cAMP responsive element modulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr18:3,263,181...3,337,688
Ensembl chr18:3,266,048...3,337,748 		JBrowse link
G Crp C-reactive protein, pentraxin-related ISO protein:increased expression:serum RGD PMID:22885951 RGD:6906884 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991 		JBrowse link
G Cttn cortactin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:143,989,468...144,024,743
Ensembl chr 7:143,989,470...144,024,746 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,150...74,200,405 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 PMID:26387944 NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030 		JBrowse link
G Dapk1 death associated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:60,749,506...60,911,005
Ensembl chr13:60,749,761...60,911,005 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157 		JBrowse link
G Dusp1 dual specificity phosphatase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102 		JBrowse link
G Dusp2 dual specificity phosphatase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:127,178,079...127,180,297
Ensembl chr 2:127,178,079...127,180,296 		JBrowse link
G Dusp4 dual specificity phosphatase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:35,274,448...35,289,106
Ensembl chr 8:35,274,451...35,287,048 		JBrowse link
G Dysf dysferlin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:83,985,344...84,188,042
Ensembl chr 6:83,985,572...84,188,042 		JBrowse link
G Egf epidermal growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965 		JBrowse link
G Egr1 early growth response 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037 		JBrowse link
G Elf2 E74-like factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:51,160,141...51,248,101
Ensembl chr 3:51,160,141...51,248,084 		JBrowse link
G Etnk1 ethanolamine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:143,112,592...143,154,272
Ensembl chr 6:143,112,947...143,178,033 		JBrowse link
G Etv6 ets variant 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:134,012,663...134,247,121
Ensembl chr 6:134,012,663...134,247,121 		JBrowse link
G Fam20a FAM20A, golgi associated secretory pathway pseudokinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:109,563,752...109,613,989
Ensembl chr11:109,560,575...109,613,105 		JBrowse link
G Faxdc2 fatty acid hydroxylase domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:57,954,508...57,983,977
Ensembl chr11:57,954,378...57,983,960 		JBrowse link
G Fcgr1 Fc receptor, IgG, high affinity I ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:96,190,225...96,201,285
Ensembl chr 3:96,190,225...96,201,285 		JBrowse link
G Fchsd2 FCH and double SH3 domains 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:100,757,836...100,933,613
Ensembl chr 7:100,742,070...100,933,612 		JBrowse link
G Fos FBJ osteosarcoma oncogene ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047 		JBrowse link
G Fosb FBJ osteosarcoma oncogene B ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:19,036,621...19,043,970
Ensembl chr 7:19,036,621...19,043,976 		JBrowse link
G Fosl2 fos-like antigen 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:32,292,599...32,315,184
Ensembl chr 5:32,293,145...32,315,186 		JBrowse link
G Foxp1 forkhead box P1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:98,902,303...99,510,587
Ensembl chr 6:98,902,299...99,499,682 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441 		JBrowse link
G Gmpr guanosine monophosphate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:45,660,905...45,699,862
Ensembl chr13:45,660,920...45,707,276 		JBrowse link
G Gng11 guanine nucleotide binding protein (G protein), gamma 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:4,003,987...4,008,445
Ensembl chr 6:4,003,904...4,008,445 		JBrowse link
G Gp1bb glycoprotein Ib, beta polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr16:18,439,069...18,441,153
Ensembl chr16:18,439,067...18,441,153 		JBrowse link
G Gstt1 glutathione S-transferase, theta 1 susceptibility ISO DNA:deletion: : RGD PMID:18328165 RGD:5490992 NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418 		JBrowse link
G H2-Aa histocompatibility 2, class II antigen A, alpha ISO DNA:polymorphism (human) RGD PMID:19811310 PMID:10457895 RGD:5147815, RGD:5147863 NCBI chr17:34,501,718...34,506,797
Ensembl chr17:34,501,718...34,506,797 		JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 ISO DNA:polymorphism (human) RGD PMID:10457895 RGD:5147863 NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393 		JBrowse link
G H2-Eb1 histocompatibility 2, class II antigen E beta ISO DNA:polymorphism (human) RGD PMID:19908388 PMID:10457895 RGD:5147587, RGD:5147863 NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648 		JBrowse link
G H2ac13 H2A clustered histone 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:21,900,582...21,901,029
Ensembl chr13:21,900,592...21,900,984 		JBrowse link
G H2bc8 H2B clustered histone 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:23,755,574...23,756,037
Ensembl chr13:23,755,570...23,756,187 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr18:36,637,980...36,648,858
Ensembl chr18:36,637,980...36,648,858 		JBrowse link
G Herpud2 HERPUD family member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:25,012,412...25,063,109
Ensembl chr 9:25,019,428...25,063,116 		JBrowse link
G Hfe homeostatic iron regulator ISO DNA:missense mutation:cds:p.C282Y (human) RGD PMID:16047841 RGD:8694357 NCBI chr13:23,886,017...23,894,837
Ensembl chr13:23,886,017...23,894,837 		JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) ISO protein:increased expression:serum,synovial fluid: RGD PMID:8255671 RGD:12910480 NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402 		JBrowse link
G Igf1r insulin-like growth factor I receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416 		JBrowse link
G Il1a interleukin 1 alpha ISO DNA:SNP:promoter:-889C>T (human) RGD PMID:8162643 RGD:7794716 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506 		JBrowse link
G Il2 interleukin 2 ISO protein:increased expression:mononuclear cell RGD PMID:21859687 RGD:5147870 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108 		JBrowse link
G Il6 interleukin 6 ISO protein:increased expression:serum: RGD PMID:9489833 RGD:7829742 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Itga2b integrin alpha 2b ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:102,344,123...102,360,709
Ensembl chr11:102,344,123...102,360,948 		JBrowse link
G Itgb5 integrin beta 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr16:33,650,021...33,769,708
Ensembl chr16:33,650,035...33,769,708 		JBrowse link
G Jmjd1c jumonji domain containing 1C ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:66,932,189...67,092,105
Ensembl chr10:66,931,904...67,092,105 		JBrowse link
G Jun jun proto-oncogene ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459 		JBrowse link
G Kat6b K(lysine) acetyltransferase 6B ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:21,549,284...21,722,546
Ensembl chr14:21,531,502...21,722,546 		JBrowse link
G Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr16:95,058,417...95,101,119
Ensembl chr16:95,058,417...95,101,119 		JBrowse link
G Klf4 Kruppel-like transcription factor 4 (gut) ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:55,527,137...55,536,984
Ensembl chr 4:55,527,143...55,532,466 		JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965 		JBrowse link
G Lacc1 laccase domain containing 1 ISO ClinVar Annotator: match by term: JUVENILE ARTHRITIS OMIM
ClinVar		 PMID:25147203 PMID:25220867 PMID:25741868 PMID:27881174 PMID:29717096 More... NCBI chr14:77,261,640...77,274,344
Ensembl chr14:77,261,640...77,274,344 		JBrowse link
G Lilra5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:4,240,643...4,246,689
Ensembl chr 7:4,240,753...4,246,462 		JBrowse link
G Lpp LIM domain containing preferred translocation partner in lipoma ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr16:24,212,100...24,811,328
Ensembl chr16:24,212,257...24,811,328 		JBrowse link
G Mad1l1 MAD1 mitotic arrest deficient 1-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:139,994,444...140,307,346
Ensembl chr 5:139,994,444...140,307,307 		JBrowse link
G Maff v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:79,230,813...79,243,278
Ensembl chr15:79,230,821...79,243,276 		JBrowse link
G Maml2 mastermind like transcriptional coactivator 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:13,296,547...13,620,829
Ensembl chr 9:13,298,306...13,620,684 		JBrowse link
G Map2 microtubule-associated protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:66,214,337...66,481,742
Ensembl chr 1:66,214,432...66,481,742 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mbl2 mannose-binding lectin (protein C) 2 ISO RGD PMID:18334024 RGD:12910845 NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087 		JBrowse link
G Mex3c mex3 RNA binding family member C ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr18:73,705,710...73,725,649
Ensembl chr18:73,706,115...73,725,646 		JBrowse link
G Mir22hg Mir22 host gene (non-protein coding) ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:75,352,365...75,357,516
Ensembl chr11:75,352,365...75,357,502 		JBrowse link
G Ms4a4a membrane-spanning 4-domains, subfamily A, member 4A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr19:11,352,827...11,370,682
Ensembl chr19:11,352,887...11,370,154 		JBrowse link
G Msn moesin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr  X:95,139,651...95,212,159
Ensembl chr  X:95,139,648...95,212,158 		JBrowse link
G Mtss1 MTSS I-BAR domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:58,813,083...58,955,805
Ensembl chr15:58,813,083...58,953,854 		JBrowse link
G Myzap myocardial zonula adherens protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:71,411,629...71,499,642
Ensembl chr 9:71,411,629...71,499,642 		JBrowse link
G Ndel1 nudE neurodevelopment protein 1 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:68,712,260...68,743,961
Ensembl chr11:68,712,260...68,762,684 		JBrowse link
G Neat1 nuclear paraspeckle assembly transcript 1 (non-protein coding) ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr19:5,874,736...5,895,508
Ensembl chr19:5,874,736...5,895,898 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:56,996,845...57,014,018
Ensembl chr 2:56,996,842...57,014,015 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:48,045,098...48,086,446
Ensembl chr 4:48,045,153...48,086,447 		JBrowse link
G Nrg1 neuregulin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:32,299,493...33,381,858
Ensembl chr 8:32,304,579...33,374,825
Ensembl chr 8:32,304,579...33,374,825 		JBrowse link
G Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:129,456,113...129,484,312
Ensembl chr 6:129,462,207...129,484,128 		JBrowse link
G Osm oncostatin M ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:4,186,831...4,191,027
Ensembl chr11:4,186,420...4,191,026 		JBrowse link
G Pacsin2 protein kinase C and casein kinase substrate in neurons 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:83,259,812...83,348,800
Ensembl chr15:83,259,808...83,348,807 		JBrowse link
G Pcyt1b phosphate cytidylyltransferase 1, choline, beta isoform ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr  X:92,698,469...92,793,557
Ensembl chr  X:92,698,469...92,793,557 		JBrowse link
G Per1 period circadian clock 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:68,985,934...69,000,791
Ensembl chr11:68,986,043...69,000,786 		JBrowse link
G Pgm5 phosphoglucomutase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr19:24,655,625...24,839,206
Ensembl chr19:24,660,380...24,839,219 		JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393 		JBrowse link
G Plk2 polo like kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:110,531,578...110,537,378
Ensembl chr13:110,531,580...110,537,378 		JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:92,421,828...92,490,481
Ensembl chr 9:92,424,276...92,490,481 		JBrowse link
G Pros1 protein S (alpha) ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr16:62,674,670...62,749,709
Ensembl chr16:62,674,670...62,749,709 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) ISO DNA: snp : cds : rs2476601 RGD PMID:15934099 RGD:6484550 NCBI chr 3:103,763,891...103,819,568
Ensembl chr 3:103,767,111...103,819,563 		JBrowse link
G R3hdm2 R3H domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:127,216,201...127,335,253
Ensembl chr10:127,216,196...127,335,253 		JBrowse link
G Rasgef1b RasGEF domain family, member 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:99,365,279...99,400,786
Ensembl chr 5:99,365,285...99,876,924 		JBrowse link
G Rbm47 RNA binding motif protein 47 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:66,173,892...66,309,297
Ensembl chr 5:66,173,892...66,330,461 		JBrowse link
G Rere arginine glutamic acid dipeptide (RE) repeats ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:150,365,372...150,706,423
Ensembl chr 4:150,366,103...150,706,423 		JBrowse link
G Rhobtb1 Rho-related BTB domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:68,987,106...69,127,621
Ensembl chr10:68,987,264...69,127,621 		JBrowse link
G Rnf103 ring finger protein 103 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:71,470,828...71,487,864
Ensembl chr 6:71,470,878...71,487,865 		JBrowse link
G Selp selectin, platelet severity ISO protein:increased expression:plasma RGD PMID:21124648 RGD:6219006 NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595 		JBrowse link
G Sh2d2a SH2 domain containing 2A ISO RGD PMID:15129233 RGD:2298870 NCBI chr 3:87,754,070...87,763,116
Ensembl chr 3:87,754,062...87,763,029 		JBrowse link
G Sh3bgrl2 SH3 domain binding glutamic acid-rich protein like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:83,430,391...83,482,345
Ensembl chr 9:83,430,380...83,520,854 		JBrowse link
G Sik1 salt inducible kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr17:32,063,222...32,074,808
Ensembl chr17:32,063,224...32,074,778 		JBrowse link
G Sipa1l1 signal-induced proliferation-associated 1 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:82,216,138...82,498,560
Ensembl chr12:82,216,094...82,498,560 		JBrowse link
G Slc11a1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 ISO DNA:repeat:promoter (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16597321 PMID:10857800 RGD:5684977 NCBI chr 1:74,414,318...74,429,974
Ensembl chr 1:74,414,354...74,425,221 		JBrowse link
G Slc22a16 solute carrier family 22 (organic cation transporter), member 16 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:40,446,317...40,480,128
Ensembl chr10:40,446,332...40,480,128 		JBrowse link
G Slc26a2 solute carrier family 26 (sulfate transporter), member 2 susceptibility ISO DNA:SNPs: : RGD PMID:17393463 RGD:13208931 NCBI chr18:61,329,926...61,344,668
Ensembl chr18:61,325,991...61,344,684 		JBrowse link
G Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:122,704,783...122,779,149
Ensembl chr 6:122,704,768...122,778,599 		JBrowse link
G Smad3 SMAD family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276 		JBrowse link
G Stab1 stabilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:30,860,974...30,890,616
Ensembl chr14:30,860,970...30,890,598 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
G Stim1 stromal interaction molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:101,909,279...102,086,525
Ensembl chr 7:101,917,013...102,086,526 		JBrowse link
G Tcf7l2 transcription factor 7 like 2, T cell specific, HMG box ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr19:55,730,227...55,922,091
Ensembl chr19:55,730,252...55,922,086 		JBrowse link
G Tfdp1 transcription factor Dp 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:13,388,273...13,428,448
Ensembl chr 8:13,388,751...13,428,448 		JBrowse link
G Tfpi tissue factor pathway inhibitor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:84,263,199...84,307,119
Ensembl chr 2:84,263,199...84,307,119 		JBrowse link
G Thbd thrombomodulin ISO protein:increased expression:serum RGD PMID:15209962 RGD:5685023 NCBI chr 2:148,246,391...148,250,108
Ensembl chr 2:148,246,386...148,250,108 		JBrowse link
G Thbs1 thrombospondin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614 		JBrowse link
G Tnfaip6 tumor necrosis factor alpha induced protein 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:51,928,125...51,946,693
Ensembl chr 2:51,928,021...51,946,698 		JBrowse link
G Tnfaip8 tumor necrosis factor, alpha-induced protein 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr18:50,112,494...50,226,296
Ensembl chr18:50,112,494...50,240,240 		JBrowse link
G Tnik TRAF2 and NCK interacting kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:28,317,362...28,724,734
Ensembl chr 3:28,317,363...28,730,007 		JBrowse link
G Treml1 triggering receptor expressed on myeloid cells-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr17:48,666,944...48,674,204
Ensembl chr17:48,666,944...48,674,204 		JBrowse link
G Ttll5 tubulin tyrosine ligase-like family, member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:85,871,417...86,100,534
Ensembl chr12:85,871,433...86,108,667 		JBrowse link
G Tubb2a tubulin, beta 2A class IIA ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:34,258,261...34,261,991
Ensembl chr13:34,258,257...34,261,990 		JBrowse link
G Ube2e1 ubiquitin-conjugating enzyme E2E 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:4,137,852...4,186,967
Ensembl chr14:4,137,837...4,186,974 		JBrowse link
G Ube3c ubiquitin protein ligase E3C ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:29,774,240...29,881,075
Ensembl chr 5:29,774,240...29,881,090 		JBrowse link
G Wasf3 WASP family, member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:146,317,411...146,410,425
Ensembl chr 5:146,321,795...146,410,425 		JBrowse link
G Wwox WW domain-containing oxidoreductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:115,166,377...116,079,451
Ensembl chr 8:115,166,395...116,079,447 		JBrowse link
G Zfand3 zinc finger, AN1-type domain 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr17:30,224,013...30,429,797
Ensembl chr17:30,223,707...30,429,802 		JBrowse link
G Zfc3h1 zinc finger, C3H1-type containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:115,220,691...115,268,677
Ensembl chr10:115,220,864...115,268,677 		JBrowse link
Sjogren's syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aire autoimmune regulator IAGP OMIM:270150 MouseDO NCBI chr10:77,865,856...77,879,444
Ensembl chr10:77,865,856...77,879,444 		JBrowse link
G Apoe apolipoprotein E onset ISO DNA:polymorphism:exon: RGD PMID:15328426 RGD:7495765 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Bdnf brain derived neurotrophic factor severity ISO protein:increased expression:serum: RGD PMID:18830907 RGD:8657019 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352 		JBrowse link
G Bst2 bone marrow stromal cell antigen 2 ISO mRNA, protein:increased expression: labial gland, CD19+ B cell, CD4-CD8-CD19-monocyte: RGD PMID:30249485 RGD:14398821 NCBI chr 8:71,986,899...71,990,116
Ensembl chr 8:71,986,899...71,990,100 		JBrowse link
G C3 complement component 3 IMP RGD PMID:17675493 RGD:7401265 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G Cast calpastatin ISO associated with Lupus Erythematosus, Systemic RGD PMID:15540513 RGD:5683622 NCBI chr13:74,840,485...74,956,993
Ensembl chr13:74,840,487...74,956,929 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 no_association ISO DNA:frameshift mutation: :p.S185_T195del (rs333) (human) RGD PMID:12412204 PMID:23773920 RGD:8551796, RGD:8551818 NCBI chr 9:123,921,557...123,934,153
Ensembl chr 9:123,921,580...123,947,736 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 IAGP OMIM:270150 MouseDO NCBI chr11:99,035,025...99,045,903
Ensembl chr11:99,035,022...99,045,903 		JBrowse link
G Cd40lg CD40 ligand ISO protein:increased expression:salivary ductal epithelium (human) RGD PMID:12472667 RGD:11520791 NCBI chr  X:56,257,448...56,269,402
Ensembl chr  X:56,257,503...56,269,402 		JBrowse link
G Crp C-reactive protein, pentraxin-related ISO associated with Arthritis, Rheumatoid;protein:increased expression:serum: RGD PMID:2353152 PMID:16013223 RGD:9491774, RGD:9491835 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 susceptibility ISO DNA:SNPs,haplotype: :+49A/G (rs231775),(rs3087243)(human)
mRNA:increased expression:salivary gland:		 RGD PMID:16869018 PMID:12528117 RGD:7421506, RGD:7421519 NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 IAGP OMIM:270150 MouseDO NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO associated with Arthritis, Rheumatoid;DNA:polymorphism: :4889A>G (human) RGD PMID:12590982 RGD:5147747 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Dgkq diacylglycerol kinase, theta ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097067 NCBI chr 5:108,794,910...108,808,696
Ensembl chr 5:108,794,559...108,817,538 		JBrowse link
G E2f1 E2F transcription factor 1 IAGP OMIM:270150 MouseDO NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812 		JBrowse link
G Fas Fas cell surface death receptor ISO
IAGP
IMP
IEP		 protein:increased expression:serum (human)
OMIM:270150
protein:decreased expression:lacrimal gland, lymphocyte (mouse)		 MouseDO
RGD		 PMID:9890678 PMID:9870874 PMID:11157873 RGD:8662410, RGD:8662451, RGD:8662436 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Gdnf glial cell line derived neurotrophic factor ISO RGD PMID:9853108 RGD:6218983 NCBI chr15:7,839,529...7,867,061
Ensembl chr15:7,840,327...7,867,056 		JBrowse link
G Gtf2i general transcription factor II I ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097066 NCBI chr 5:134,266,686...134,346,571
Ensembl chr 5:134,266,688...134,343,614 		JBrowse link
G H2-Aa histocompatibility 2, class II antigen A, alpha susceptibility ISO DNA:polymorphism:cds:HLA-DQA1*0101 (human)
DNA:polymorphisms::HLA-DQA1*0501,LA-DQA1*0301/2;		 RGD PMID:11555411 PMID:21315052 RGD:5147809, RGD:7421543 NCBI chr17:34,501,718...34,506,797
Ensembl chr17:34,501,718...34,506,797 		JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 susceptibility ISO DNA:polymorphisms:cds:HLA-DQB1*0201 (human)
associated with Chronic Hepatitis C;DNA:polymorphism:cds:HLA-DQB1*02 (human)
DNA:polymorphisms, haplotypes:cds:HLA-DQB1*0201, HLA-DQB1*0401, HLA-DQB1*0601 (human)		 RGD PMID:21315052 PMID:17489060 PMID:8468491 RGD:7421543, RGD:36174022, RGD:7483566 NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393 		JBrowse link
G H2-Eb1 histocompatibility 2, class II antigen E beta susceptibility ISO DNA:polymorphism:cds:HLA-DRB1*0301 (human) RGD PMID:11555411 RGD:5147809 NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648 		JBrowse link
G Hmox1 heme oxygenase 1 treatment ISO RGD PMID:24941846 RGD:10450595 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 ISO RGD PMID:19264855 RGD:10054311 NCBI chr11:50,266,084...50,277,355
Ensembl chr11:50,267,817...50,277,355 		JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment ISO
IMP
IEP		 protein:increased expression:salivary gland
protein:increased expression:plasma		 RGD PMID:11359451 PMID:21589878 PMID:15037117 RGD:8158122, RGD:8547705, RGD:8547696 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113 		JBrowse link
G Id3 inhibitor of DNA binding 3 IAGP OMIM:270150 MouseDO NCBI chr 4:135,871,133...135,872,703
Ensembl chr 4:135,870,808...135,873,066 		JBrowse link
G Ifng interferon gamma IMP
ISO		 RGD PMID:15584966 PMID:28421993 RGD:8142390, RGD:14975117 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Il10 interleukin 10 ISO RGD PMID:12233881 RGD:1580479 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il12a interleukin 12a ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097067 NCBI chr 3:68,597,977...68,605,881
Ensembl chr 3:68,597,977...68,605,880 		JBrowse link
G Il13 interleukin 13 ISO protein:increased expression:serum RGD PMID:12051401 RGD:8549582 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529 		JBrowse link
G Il17a interleukin 17A IMP RGD PMID:21182786 RGD:8696035 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720 		JBrowse link
G Il18 interleukin 18 ISO protein:increased expression:saliva RGD PMID:23906036 RGD:8655918 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO DNA:repeats:intron:IVS2+914_1000dup IL1RN*2 (human)
protein:increased expression:conjunctiva (human)		 RGD PMID:9646842 PMID:11527941 RGD:8549786, RGD:8549807 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506 		JBrowse link
G Il2 interleukin 2 IAGP OMIM:270150 MouseDO NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108 		JBrowse link
G Il23r interleukin 23 receptor ISO protein:increased expression:minor salivary gland: RGD PMID:22262980 RGD:8549566 NCBI chr 6:67,399,906...67,468,838
Ensembl chr 6:67,399,916...67,468,839 		JBrowse link
G Il2ra interleukin 2 receptor, alpha chain IAGP OMIM:270150 MouseDO NCBI chr 2:11,647,603...11,698,005
Ensembl chr 2:11,647,618...11,698,004 		JBrowse link
G Il4 interleukin 4 IAGP OMIM:270150 MouseDO NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Il6 interleukin 6 severity ISO protein:increased expression:plasma:
DNA:polymorphims:promoter:-174G>C(human)		 RGD PMID:11426023 PMID:11426023 RGD:7829718, RGD:7829718 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Irak1bp1 interleukin-1 receptor-associated kinase 1 binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097067 NCBI chr 9:82,711,859...82,729,741
Ensembl chr 9:82,711,593...82,729,740 		JBrowse link
G Itsn2 intersectin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097067 NCBI chr12:4,642,792...4,763,952
Ensembl chr12:4,642,638...4,763,962 		JBrowse link
G Lta lymphotoxin A no_association
susceptibility		 IMP
ISO		 DNA:SNPs: :multiple (human)
DNA:SNP, haplotype:intron: (rs909253) (human)
protein:increased expression:saliva, serum		 RGD PMID:20952683 PMID:22294627 PMID:22294627 PMID:20952683 RGD:8548776, RGD:8548787, RGD:8548787, RGD:8548776 NCBI chr17:35,422,141...35,424,568
Ensembl chr17:35,422,141...35,424,327 		JBrowse link
G Map3k14 mitogen-activated protein kinase kinase kinase 14 IAGP OMIM:270150 MouseDO NCBI chr11:103,110,590...103,158,227
Ensembl chr11:103,110,588...103,158,298 		JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO RGD PMID:19332626 RGD:8693671 NCBI chr 9:7,445,822...7,455,975
Ensembl chr 9:7,445,822...7,455,975 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO protein:increased activity:saliva RGD PMID:15316122 PMID:9923658 RGD:8547814, RGD:8547858 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770 		JBrowse link
G Muc16 mucin 16 ISO mRNA, protein:increased expression:conjunctival epithelial cell, tear RGD PMID:19122828 RGD:7364772 NCBI chr 9:18,406,741...18,586,117
Ensembl chr 9:18,406,751...18,585,826 		JBrowse link
G Muc19 mucin 19 ISO
IAGP		 mRNA:decreased expression:conjunctival epithelial cell
OMIM:270150		 MouseDO
RGD		 PMID:18184611 RGD:7364736 NCBI chr15:91,722,531...91,832,440
Ensembl chr15:91,722,531...91,832,447 		JBrowse link
G Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric ISO mRNA:decreased expression:conjunctival epithelial cell RGD PMID:18184611 RGD:7364736 NCBI chr 7:141,342,695...141,372,964
Ensembl chr 7:141,342,709...141,372,968 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28135245 NCBI chr 5:134,248,907...134,258,479
Ensembl chr 5:134,248,907...134,258,479 		JBrowse link
G Nefl neurofilament, light polypeptide ISO protein:increased expression:CSF (human) RGD PMID:32423153 RGD:127284890 NCBI chr14:68,321,312...68,326,544
Ensembl chr14:68,321,312...68,326,544 		JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha IAGP
IMP		 OMIM:270150 MouseDO
RGD		 PMID:20696914 RGD:126908016 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432 		JBrowse link
G Phip pleckstrin homology domain interacting protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097067 NCBI chr 9:82,748,212...82,857,776
Ensembl chr 9:82,748,212...82,857,569 		JBrowse link
G Pon1 paraoxonase 1 ISO protein:decreased activity:serum (human) RGD PMID:20497955 RGD:8547550 NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946 		JBrowse link
G Prdm1 PR domain containing 1, with ZNF domain ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097067 NCBI chr10:44,313,170...44,404,579
Ensembl chr10:44,313,173...44,404,497 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) no_association ISO DNA:snp:cds:c.1858C>T (human) RGD PMID:16163373 PMID:15933742 RGD:11534998, RGD:11534999 NCBI chr 3:103,763,891...103,819,568
Ensembl chr 3:103,767,111...103,819,563 		JBrowse link
G Pttg1 pituitary tumor-transforming gene 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097067 NCBI chr11:43,311,071...43,318,290
Ensembl chr11:43,311,077...43,317,078 		JBrowse link
G Reg1 regenerating islet-derived 1 ISO protein:increased expression:minor salivary gland, salivary ductal epithelium (human) RGD PMID:19016805 RGD:9850137 NCBI chr 6:78,402,966...78,405,651
Ensembl chr 6:78,399,694...78,405,650 		JBrowse link
G Satb1 special AT-rich sequence binding protein 1 IAGP OMIM:270150 MouseDO NCBI chr17:52,043,215...52,140,318
Ensembl chr17:52,043,215...52,140,318 		JBrowse link
G Selp selectin, platelet ISO protein:increased expression:plasma RGD PMID:19832990 RGD:6478702 NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595 		JBrowse link
G St14 suppression of tumorigenicity 14 (colon carcinoma) IAGP OMIM:270150 MouseDO NCBI chr 9:30,999,886...31,043,138
Ensembl chr 9:31,000,698...31,043,149 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 susceptibility
no_association		 ISO DNA:SNP:intron: (rs7582694) (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP:intron: (rs7574865) (human)		 CTD
RGD		 PMID:24097066 PMID:24097067 PMID:20535138 PMID:20360187 PMID:18273036 RGD:8661690, RGD:8661709, RGD:8661708 NCBI chr 1:52,026,265...52,146,348
Ensembl chr 1:52,026,307...52,146,348 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 severity IMP
IAGP
IEP		 OMIM:270150 MouseDO
RGD		 PMID:9358754 PMID:7554451 RGD:7394829, RGD:7394845 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Thbs1 thrombospondin 1 IAGP OMIM:270150 MouseDO NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614 		JBrowse link
G Tnf tumor necrosis factor treatment ISO DNA:polymorphism: :-1031T>C(human) RGD PMID:22703762 PMID:24941846 RGD:7394766, RGD:10450595 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tnfaip3 tumor necrosis factor, alpha-induced protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097066 PMID:24097067 NCBI chr10:18,876,658...18,891,158
Ensembl chr10:18,876,658...18,891,405 		JBrowse link
G Tnip1 TNFAIP3 interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097067 NCBI chr11:54,801,613...54,853,766
Ensembl chr11:54,801,611...54,853,743 		JBrowse link
G Traf3ip2 TRAF3 interacting protein 2 IAGP OMIM:270150 MouseDO NCBI chr10:39,488,930...39,531,303
Ensembl chr10:39,488,930...39,531,303 		JBrowse link
G Vim vimentin ISO RGD PMID:6352937 RGD:6480477 NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637 		JBrowse link
G Vip vasoactive intestinal polypeptide IDA RGD PMID:22059987 RGD:5685375 NCBI chr10:5,589,131...5,597,617
Ensembl chr10:5,589,218...5,597,617 		JBrowse link
Sjögren-Mikulicz Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstm1 glutathione S-transferase, mu 1 susceptibility ISO DNA:deletion: : RGD PMID:10616008 RGD:5491001 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289 		JBrowse link
Systemic Juvenile Rheumatoid Arthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ido1 indoleamine 2,3-dioxygenase 1 IMP RGD PMID:26914138 RGD:11529541 NCBI chr 8:25,074,148...25,086,987
Ensembl chr 8:25,074,152...25,087,025 		JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD
OMIM		 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Il6ra interleukin 6 receptor, alpha treatment ISO RGD PMID:18358927 RGD:10402823 NCBI chr 3:89,776,631...89,820,503
Ensembl chr 3:89,771,366...89,820,503 		JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) susceptibility ISO CTD Direct Evidence: marker/mechanism OMIM
CTD		 NCBI chr10:75,695,187...75,696,111
Ensembl chr10:75,695,187...75,696,074 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18288
    disease of anatomical entity 15573
      musculoskeletal system disease 7864
        connective tissue disease 5343
          rheumatic disease 714
            rheumatoid arthritis 447
              Caplan's syndrome 0
              Felty's syndrome 0
              Rheumatoid Nodule 0
              Rheumatoid Vasculitis 0
              Sjogren's syndrome + 67
              Sjögren-Mikulicz Syndrome 1
              adult-onset Still's disease 2
              juvenile rheumatoid arthritis + 152
              palindromic rheumatism 0
Path 2
Term Annotations click to browse term
  disease 18288
    disease of anatomical entity 15573
      Skin and Connective Tissue Diseases 6868
        connective tissue disease 5343
          bone disease 3851
            bone inflammation disease 1316
              arthropathy 1294
                arthritis 883
                  rheumatoid arthritis 447
                    Caplan's syndrome 0
                    Felty's syndrome 0
                    Rheumatoid Nodule 0
                    Rheumatoid Vasculitis 0
                    Sjogren's syndrome + 67
                    Sjögren-Mikulicz Syndrome 1
                    adult-onset Still's disease 2
                    juvenile rheumatoid arthritis + 152
                    palindromic rheumatism 0
paths to the root