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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:myocardial infarction
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Accession:DOID:5844 term browser browse the term
Definition:A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia. (DO)
Synonyms:exact_synonym: Cardiovascular Stroke;   Heart Attacks;   MCI2;   MYOCARDIAL INFARCTION, SUSCEPTIBILITY TO;   MYOCARDIAL INFARCTION, SUSCEPTIBILITY TO, 2;   Myocardial Infarct;   Myocardial Infarctions;   cardiovascular strokes;   heart attack;   myocardial infarcts
 narrow_synonym: MCI1;   MYOCARDIAL INFARCTION, PROTECTION AGAINST;   MYOCARDIAL INFARCTION, SUSCEPTIBILITY TO, 1;   post-operative myocardial infarction
 broad_synonym: F7-RELATED CONDITION
 related_synonym: MYOCARDIAL INFARCTION, DECREASED SUSCEPTIBILITY TO
 primary_id: MESH:D009203
 alt_id: MIM:608446;   MIM:608557
 xref: EFO:0000612;   EFO:0009953;   NCI:C27996
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:
myocardial infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC9 ATP binding cassette subfamily C member 9 IAGP ClinVar Annotator: match by term: Myocardial infarction ClinVar PMID:16563363 PMID:18239147 PMID:20474083 PMID:21846889 PMID:23739550 More... NCBI chr12:21,797,389...21,941,426
Ensembl chr12:21,797,389...21,942,543
JBrowse link
G ACE angiotensin I converting enzyme treatment
susceptibility
IEA
IAGP
EXP
ISO
ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Type 1;DNA:deletion:intron:IVS16+1464-1751del (human)
associated with Myocardial Reperfusion Injury
ClinVar
CTD
RGD
PMID:1313972 PMID:1319114 PMID:1328889 PMID:1386652 PMID:1976655 More... RGD:1331525, RGD:9685449, RGD:1558664, RGD:7829785, RGD:6893480 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
JBrowse link
G ACE2 angiotensin converting enzyme 2 treatment ISO RGD PMID:15671045 PMID:23959549 RGD:1558664, RGD:9685449 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236
JBrowse link
G ACTA2 actin alpha 2, smooth muscle EXP CTD Direct Evidence: marker/mechanism CTD PMID:24358288 NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,934,822...88,991,339
JBrowse link
G ACVR2A activin A receptor type 2A ISO mRNA:decreased expression:myocardium (mouse) RGD PMID:32427381 RGD:329849118 NCBI chr 2:147,844,517...147,930,822
Ensembl chr 2:147,844,517...147,930,826
JBrowse link
G ACVR2B activin A receptor type 2B ISO mRNA:decreased expression:myocardium (mouse) RGD PMID:32427381 RGD:329849118 NCBI chr 3:38,453,890...38,493,142
Ensembl chr 3:38,453,890...38,493,142
JBrowse link
G ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif 1 ISO RGD PMID:15625312 RGD:9681751 NCBI chr21:26,835,755...26,845,409
Ensembl chr21:26,835,755...26,845,409
JBrowse link
G ADD1 adducin 1 no_association IAGP DNA:missense mutation:cds:p.G460W (human) RGD PMID:17082469 PMID:16420563 RGD:5147995, RGD:5148001 NCBI chr 4:2,843,844...2,930,062
Ensembl chr 4:2,843,844...2,930,076
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing disease_progression ISO RGD PMID:21326342 RGD:5686351 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
JBrowse link
G ADIPOR1 adiponectin receptor 1 ISO mRNA, protein:decreased expression:heart left ventricle RGD PMID:16415076 RGD:1625764 NCBI chr 1:202,940,825...202,958,572
Ensembl chr 1:202,940,826...202,958,572
JBrowse link
G ADIPOR2 adiponectin receptor 2 ISO mRNA, protein:decreased expression:heart left ventricle RGD PMID:16415076 RGD:1625764 NCBI chr12:1,691,070...1,788,674
Ensembl chr12:1,688,574...1,788,674
JBrowse link
G ADORA1 adenosine A1 receptor EXP CTD Direct Evidence: therapeutic CTD PMID:12160945 NCBI chr 1:203,127,726...203,167,405
Ensembl chr 1:203,090,654...203,167,405
JBrowse link
G ADORA3 adenosine A3 receptor EXP CTD Direct Evidence: therapeutic CTD PMID:12160945 PMID:20132822 NCBI chr 1:111,499,429...111,503,633
Ensembl chr 1:111,499,429...111,503,633
JBrowse link
G ADRA2B adrenoceptor alpha 2B IAGP RGD PMID:12535806 RGD:1559314 NCBI chr 2:96,112,876...96,116,571
Ensembl chr 2:96,112,876...96,116,571
JBrowse link
G ADRB1 adrenoceptor beta 1 IEA
ISO
GAD
RGD
PMID:15118671 PMID:17143192 RGD:1331525, RGD:7241557 NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904
JBrowse link
G ADRB2 adrenoceptor beta 2 susceptibility IAGP
ISO
DNA:polymorphisms: :p.G16R, p.Q27E, p.T164I
mRNA:decreased expression:heart
RGD PMID:15520258 PMID:12400771 RGD:1601126, RGD:8548519 NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623
JBrowse link
G AGER advanced glycosylation end-product specific receptor susceptibility ISO
IAGP
mRNA:increased expression:left ventricle myocardium (rat)
DNA:polymorphism:promoter:-429T>C (human)
RGD PMID:19910580 PMID:16728681 RGD:2325647, RGD:1625333 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322
JBrowse link
G AGT angiotensinogen susceptibility ISO
EXP
IEA
IAGP
CTD Direct Evidence: marker/mechanism
associated with Coronary Artery Disease;DNA:polymorphism: :p.M235T (human)
associated with hypertension;DNA:polymorphism: :p.M235T
CTD
RGD
PMID:1668233 PMID:16413583 PMID:21167013 PMID:15118671 PMID:11393670 More... RGD:5129191, RGD:1331525, RGD:1566452, RGD:1601132 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
JBrowse link
G AGTR1 angiotensin II receptor type 1 susceptibility
no_association
IAGP
ISO
IEA
DNA:polymorphism:3' utr:1166A>C
DNA:polymorphism:3' utr:1166A>C (human)
RGD
GAD
PMID:16061119 PMID:9652322 PMID:15118671 PMID:9857918 RGD:1601150, RGD:10047101, RGD:1331525, RGD:1566499 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008
JBrowse link
G AHSG alpha 2-HS glycoprotein IEP protein:increased expression:plasma RGD PMID:19029462 RGD:2313810 NCBI chr 3:186,613,060...186,621,318
Ensembl chr 3:186,613,060...186,621,318
JBrowse link
G AIMP1 aminoacyl tRNA synthetase complex interacting multifunctional protein 1 ISO RGD PMID:14732363 RGD:1580021 NCBI chr 4:106,315,544...106,349,456
Ensembl chr 4:106,315,544...106,349,456
JBrowse link
G AK1 adenylate kinase 1 treatment ISO RGD PMID:22229508 RGD:11100025 NCBI chr 9:127,866,480...127,879,621
Ensembl chr 9:127,866,486...127,877,675
JBrowse link
G AKT1 AKT serine/threonine kinase 1 IEP
ISO
protein:increased serine phosphorylation:platelet
protein:decreased serine phosphorylation:heart
RGD PMID:20467748 PMID:20352476 RGD:5509094, RGD:10041035 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member IAGP DNA:missense mutation: :p.E487K (human) RGD PMID:12452318 RGD:2311152 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
JBrowse link
G ALOX5AP arachidonate 5-lipoxygenase activating protein no_association IAGP
IEA
DNA:snps:multiple (human) RGD
GAD
PMID:14770184 PMID:15118671 PMID:19046748 RGD:1578317, RGD:1331525, RGD:2313891 NCBI chr13:30,713,485...30,764,426
Ensembl chr13:30,713,478...30,764,426
JBrowse link
G ANG angiogenin IMP RGD PMID:18462761 RGD:2325719 NCBI chr14:20,684,177...20,694,186
Ensembl chr14:20,684,177...20,698,971
JBrowse link
G ANGPT1 angiopoietin 1 ISO mRNA, protein:decreased expression:myocardium RGD PMID:15364619 RGD:1626168 NCBI chr 8:107,249,482...107,497,918
Ensembl chr 8:107,249,482...107,498,055
JBrowse link
G ANGPT2 angiopoietin 2 ISO protein:increased expression:left ventricular wall, heart septum (rat) RGD PMID:16714360 RGD:1601493 NCBI chr 8:6,499,632...6,563,245
Ensembl chr 8:6,499,632...6,563,409
JBrowse link
G ANXA5 annexin A5 susceptibility
no_association
IAGP
IEP
ISO
DNA:polymorphism: :-1C>T (human)
protein:increased expression:plasma
protein:altered localization:cardiac muscle cell, sarcolemma
RGD PMID:12200370 PMID:8814351 PMID:16025836 PMID:16501019 RGD:2317542, RGD:2317543, RGD:1578384, RGD:2317541 NCBI chr 4:121,667,946...121,696,980
Ensembl chr 4:121,667,946...121,696,995
JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 susceptibility IAGP DNA:polymorphism:exon 5: G>A (human) RGD PMID:18712175 RGD:401827276 NCBI chr14:20,455,226...20,457,767
Ensembl chr14:20,455,191...20,457,772
JBrowse link
G APOA1 apolipoprotein A1 no_association IDA
IEA
IAGP
DNA:polymorphisms RGD
GAD
PMID:20176799 PMID:15118671 PMID:10428310 RGD:2325759, RGD:1331525, RGD:1578442 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622
JBrowse link
G APOA4 apolipoprotein A4 susceptibility
no_association
IEA
IAGP
associated with Diabetes Mellitus, Type 2; DNA:missense mutation:cds:p.Q360H (human)
DNA:mutation:intron:IVS2 (human)
GAD
RGD
PMID:15118671 PMID:7958503 PMID:10428310 RGD:1331525, RGD:5685678, RGD:1578442 NCBI chr11:116,820,700...116,823,304
Ensembl chr11:116,820,700...116,823,304
JBrowse link
G APOB apolipoprotein B IEA GAD PMID:15118671 RGD:1331525 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073
JBrowse link
G APOC3 apolipoprotein C3 no_association IAGP
IEA
ClinVar Annotator: match by term: Myocardial infarction, susceptibility to ClinVar
RGD
PMID:10428310 PMID:15118671 RGD:1578442, RGD:1331525 NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072
JBrowse link
G APOE apolipoprotein E susceptibility IAGP
EXP
IEA
DNA:missense mutations, haplotypes:cds:p.C112R, p.R158C (human)
CTD Direct Evidence: marker/mechanism
DNA:missense mutations, haplotype:cds:p.C112R, p.C158R (human)
CTD
RGD
PMID:10587578 PMID:17217375 PMID:10090925 PMID:15118671 RGD:1601229, RGD:10449412, RGD:1331525 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
G APOH apolipoprotein H IDA
ISO
RGD PMID:15322656 PMID:12826288 RGD:2313985, RGD:10054111 NCBI chr17:66,212,033...66,229,415
Ensembl chr17:66,212,033...66,256,525
JBrowse link
G ATG7 autophagy related 7 ISO mRNA:increased expression:plantaris RGD PMID:24427319 RGD:11557988 NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665
JBrowse link
G ATM ATM serine/threonine kinase ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:24358288 PMID:24358288 RGD:10053570 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102
JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 EXP CTD Direct Evidence: therapeutic CTD PMID:29702141 NCBI chr 1:116,373,244...116,404,774
Ensembl chr 1:116,372,668...116,410,261
JBrowse link
G ATP5F1D ATP synthase F1 subunit delta treatment ISO protein:decreased expression:myocardium (rat) RGD PMID:29300489 PMID:23809007 RGD:13792656, RGD:13792681 NCBI chr19:1,241,751...1,244,825
Ensembl chr19:1,241,746...1,244,825
JBrowse link
G ATP5PO ATP synthase peripheral stalk subunit OSCP treatment ISO RGD PMID:24692845 RGD:13801194 NCBI chr21:33,903,453...33,915,804
Ensembl chr21:33,903,453...33,915,814
JBrowse link
G AVPR1A arginine vasopressin receptor 1A ISO RGD PMID:16423716 RGD:2300376 NCBI chr12:63,142,759...63,151,201
Ensembl chr12:63,142,759...63,151,201
JBrowse link
G BAK1 BCL2 antagonist/killer 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29122578 NCBI chr 6:33,572,552...33,580,276
Ensembl chr 6:33,572,547...33,580,293
JBrowse link
G BAX BCL2 associated X, apoptosis regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:20079142 PMID:25450231 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:19027736 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L1 BCL2 like 1 ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:20079142 PMID:17467744 RGD:1643494 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BDKRB1 bradykinin receptor B1 ISO mRNA:increased expression:heart RGD PMID:12489796 RGD:704379 NCBI chr14:96,256,210...96,264,763
Ensembl chr14:96,256,210...96,268,967
JBrowse link
G BDKRB2 bradykinin receptor B2 ISO mRNA:increased expression:heart RGD PMID:12489796 RGD:704379 NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166
JBrowse link
G BECN1 beclin 1 treatment ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:20079142 PMID:20079142 RGD:11561913 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 ISO RGD PMID:15081314 RGD:2293137 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
JBrowse link
G BNIP3 BCL2 interacting protein 3 ISO mRNA:increased expression:plantaris RGD PMID:24427319 RGD:11557988 NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,967,684...131,981,967
JBrowse link
G BRAP BRCA1 associated protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:19198608 NCBI chr12:111,642,146...111,685,956
Ensembl chr12:111,642,146...111,685,956
JBrowse link
G BRINP3 BMP/retinoic acid inducible neural specific 3 susceptibility IAGP DNA:SNPs:3' end: RGD PMID:18430236 RGD:14398488 NCBI chr 1:190,097,658...190,477,864
Ensembl chr 1:190,097,658...190,478,404
JBrowse link
G C3 complement C3 ISO mRNA, protein:increased expression:myocardium RGD PMID:16996480 RGD:1600605 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G C7 complement C7 ISO Protein:increased activity:serum, myocardium RGD PMID:15724448 RGD:1599522 NCBI chr 5:40,909,497...40,984,643
Ensembl chr 5:40,909,492...41,020,216
JBrowse link
G C8A complement C8 alpha chain ISO RGD PMID:7515561 RGD:1600501 NCBI chr 1:56,854,797...56,918,223
Ensembl chr 1:56,854,768...56,918,223
JBrowse link
G C8B complement C8 beta chain ISO RGD PMID:7515561 RGD:1600501 NCBI chr 1:56,929,207...56,966,015
Ensembl chr 1:56,929,207...56,974,383
JBrowse link
G CACYBP calcyclin binding protein ISO mRNA:increased expression:heart RGD PMID:16440310 RGD:2326117 NCBI chr 1:174,999,435...175,012,027
Ensembl chr 1:174,999,163...175,012,027
JBrowse link
G CAMK2D calcium/calmodulin dependent protein kinase II delta treatment ISO mRNA, protein:splice variants, increased expression:heart left ventricle (rat) RGD PMID:26067684 RGD:11097969 NCBI chr 4:113,451,032...113,761,738
Ensembl chr 4:113,418,054...113,761,927
JBrowse link
G CASP1 caspase 1 severity
ameliorates
ISO RGD PMID:17303764 PMID:33389498 RGD:2315913, RGD:242905187 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250
JBrowse link
G CASP3 caspase 3 ameliorates
treatment
EXP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:25450231 PMID:28622474 PMID:27904666 RGD:329333030, RGD:13782309 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASR calcium sensing receptor ISO protein:increased expression:myocardium (rat) RGD PMID:22527939 RGD:7205672 NCBI chr 3:122,183,668...122,291,629
Ensembl chr 3:122,183,668...122,291,629
JBrowse link
G CAT catalase ISO
EXP
CTD Direct Evidence: therapeutic CTD
RGD
PMID:21600015 PMID:14575298 RGD:1581148 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CAV3 caveolin 3 ISO Protein:increased expression:cytosol
mRNA, protein; increased expression; myocardium (rat)
RGD PMID:12566108 PMID:29438664 RGD:1599542, RGD:126925221 NCBI chr 3:8,733,802...8,746,758
Ensembl chr 3:8,733,802...8,841,808
JBrowse link
G CCL2 C-C motif chemokine ligand 2 treatment ISO
IAGP
protein:increased expression:serum
DNA:snp:promoter:g.-2518A>G (human)
RGD PMID:18459941 PMID:18753699 PMID:16116069 RGD:2307033, RGD:8549616, RGD:1581161 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO mRNA:increased expression:heart (rat) RGD PMID:18954648 RGD:4890013 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G CCN1 cellular communication network factor 1 ISO mRNA,protein:increased expression:myocardium (mouse) RGD PMID:15117851 RGD:329845570 NCBI chr 1:85,580,761...85,583,950
Ensembl chr 1:85,580,761...85,584,589
JBrowse link
G CCN2 cellular communication network factor 2 treatment ISO mRNA:increased expression:left ventricle (rat) RGD PMID:18167060 PMID:29849775 RGD:2314623, RGD:35673318 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372
JBrowse link
G CCNA2 cyclin A2 ISO protein:increased expression:cardiomyocyte: RGD PMID:23634243 RGD:10054471 NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883
JBrowse link
G CCR2 C-C motif chemokine receptor 2 IAGP RGD PMID:12719858 PMID:12853162 RGD:1581177, RGD:1581174 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940
JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO RGD PMID:18954648 RGD:4890013 NCBI chr 3:46,210,696...46,266,706
Ensembl chr 3:46,130,890...46,266,706
JBrowse link
G CCT7 chaperonin containing TCP1 subunit 7 IAGP ClinVar Annotator: match by term: Myocardial infarction, susceptibility to, 1 ClinVar PMID:24213632 NCBI chr 2:73,234,308...73,253,005
Ensembl chr 2:73,233,420...73,253,021
JBrowse link
G CD14 CD14 molecule no_association IAGP associated with Coronary Artery Disease;DNA:SNP:promoter RGD PMID:17436151 PMID:10195920 PMID:14587643 RGD:2314155, RGD:1580252, RGD:1580255 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700
JBrowse link
G CD36 CD36 molecule (CD36 blood group) severity ISO RGD PMID:22128087 RGD:6893560 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277
JBrowse link
G CD40LG CD40 ligand IEP protein:increased expression:serum RGD PMID:17635572 RGD:2314209 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390
JBrowse link
G CD59 CD59 molecule (CD59 blood group) ISO protein:decreased expression:myocardium RGD PMID:7515561 RGD:1600501 NCBI chr11:33,703,010...33,736,479
Ensembl chr11:33,703,010...33,736,479
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B treatment ISO RGD PMID:22492676 PMID:22492676 RGD:10045366, RGD:10045366 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369
JBrowse link
G CFL1 cofilin 1 treatment ISO RGD PMID:24292258 RGD:11570534 NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026
JBrowse link
G CFTR CF transmembrane conductance regulator ISO associated with Myocardial Reperfusion Injury RGD PMID:23221371 RGD:11566046 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971
JBrowse link
G CHI3L1 chitinase 3 like 1 IEP protein:increased secretion:serum (human) RGD PMID:18480670 RGD:4892633 NCBI chr 1:203,178,931...203,186,704
Ensembl chr 1:203,178,931...203,186,704
JBrowse link
G CIITA class II major histocompatibility complex transactivator susceptibility
no_association
IAGP DNA:polymorphism:promoter:-168A>G RGD PMID:15821736 PMID:17183695 RGD:1358146, RGD:5491201 NCBI chr16:10,866,206...10,943,021
Ensembl chr16:10,866,222...10,943,021
JBrowse link
G CKB creatine kinase B EXP CTD Direct Evidence: marker/mechanism CTD PMID:12359538 NCBI chr14:103,519,667...103,522,830
Ensembl chr14:103,519,667...103,522,833
JBrowse link
G CKM creatine kinase, M-type EXP CTD Direct Evidence: marker/mechanism CTD PMID:3279722 PMID:12359538 NCBI chr19:45,306,413...45,322,875
Ensembl chr19:45,306,413...45,322,875
JBrowse link
G CLU clusterin treatment IDA RGD PMID:20854280 RGD:9068409 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700
JBrowse link
G COL1A1 collagen type I alpha 1 chain treatment ISO RGD PMID:25636075 RGD:11041598 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G COL3A1 collagen type III alpha 1 chain treatment ISO RGD PMID:25636075 RGD:11041598 NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746
JBrowse link
G COL4A1 collagen type IV alpha 1 chain susceptibility IAGP DNA:polymorphism: :p.Q1334H (human) RGD PMID:18077766 RGD:2311341 NCBI chr13:110,148,963...110,307,157
Ensembl chr13:110,148,963...110,307,202
JBrowse link
G COL6A3 collagen type VI alpha 3 chain IAGP DNA:SNP:CDS:E1386K (rs146092501) (human) RGD PMID:30226566 RGD:401851058 NCBI chr 2:237,324,018...237,414,164
Ensembl chr 2:237,324,003...237,414,328
JBrowse link
G CREB1 cAMP responsive element binding protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19027736 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988
JBrowse link
G CREM cAMP responsive element modulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:19027736 NCBI chr10:35,126,846...35,212,958
Ensembl chr10:35,126,791...35,212,958
JBrowse link
G CRP C-reactive protein ISO
IEP
protein:increased expression:serum
associated with Angina, Unstable;
RGD PMID:21046814 PMID:9761079 PMID:22446866 RGD:5131456, RGD:9491780, RGD:6482304 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
JBrowse link
G CS citrate synthase severity ISO protein:decreased expression:diaphragm, mitochondrion RGD PMID:1877670 PMID:34416105 RGD:243048469, RGD:243048471 NCBI chr12:56,271,699...56,300,330
Ensembl chr12:56,271,699...56,300,391
JBrowse link
G CSF2 colony stimulating factor 2 ISO RGD PMID:21326109 RGD:5131507 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170
JBrowse link
G CSF3 colony stimulating factor 3 treatment IDA RGD PMID:15639484 RGD:11039417 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813
JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 ISO RGD PMID:15090263 RGD:11565830 NCBI chr20:472,498...543,790
Ensembl chr20:472,498...543,835
JBrowse link
G CSNK2B casein kinase 2 beta ISO RGD PMID:15090263 RGD:11565830 NCBI chr 6:31,666,080...31,670,067
Ensembl chr 6:31,665,227...31,670,343
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 IAGP DNA:SNP:CDS:49A>G (human) RGD PMID:17652883 RGD:2301976 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965
JBrowse link
G CTSB cathepsin B ISO protein:increased activity:serum, heart (rat) RGD PMID:19958779 RGD:2315501 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533
JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 ISO mRNA:increased expression:heart left ventricle RGD PMID:19187644 PMID:11820456 RGD:2306567, RGD:632503 NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493
JBrowse link
G CYBA cytochrome b-245 alpha chain ISO mRNA:increased expression:myocardium
mRNA:increase expression:ventricle myocardium:
RGD PMID:18762777 PMID:11243862 RGD:2317860, RGD:1599690 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083
JBrowse link
G CYBB cytochrome b-245 beta chain ISO mRNA:increase expression:ventricle myocardium RGD PMID:11243862 RGD:1599690 NCBI chr  X:37,780,059...37,813,461
Ensembl chr  X:37,780,018...37,813,461
JBrowse link
G CYP11B1 cytochrome P450 family 11 subfamily B member 1 ISO RGD PMID:18689429 RGD:2307303 NCBI chr 8:142,872,357...142,879,825
Ensembl chr 8:142,872,356...142,879,846
JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 ISO RGD PMID:18689429 RGD:2307303 NCBI chr 8:142,910,559...142,917,843
Ensembl chr 8:142,910,559...142,917,843
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 ameliorates ISO RGD PMID:33389498 RGD:242905187 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 susceptibility IAGP DNA:polymorphism RGD PMID:17126841 RGD:1625380 NCBI chr 1:59,893,308...59,969,212
Ensembl chr 1:59,893,308...59,926,773
JBrowse link
G CYP2R1 cytochrome P450 family 2 subfamily R member 1 IAGP DNA:SNP:CDS:rs2060793, rs1993116, rs10766197 (human) RGD PMID:29804528 RGD:401901167 NCBI chr11:14,877,440...14,892,443
Ensembl chr11:14,877,440...14,892,231
JBrowse link
G DAB2 DAB adaptor protein 2 ISO protein:increased expression:cardiomyocyte RGD PMID:20666606 PMID:21762377 RGD:7243156 RGD:7243158 NCBI chr 5:39,371,677...39,424,980
Ensembl chr 5:39,371,675...39,462,300
JBrowse link
G DAB2IP DAB2 interacting protein onset EXP
IAGP
CTD Direct Evidence: marker/mechanism
DNA:SNP:CDS:intron 1 (rs7025486) (human)
CTD
RGD
PMID:20622881 PMID:20622881 RGD:401901599 NCBI chr 9:121,567,074...121,785,530
Ensembl chr 9:121,567,057...121,785,530
JBrowse link
G DAG1 dystroglycan 1 treatment ISO RGD PMID:12034665 RGD:11541047 NCBI chr 3:49,468,948...49,535,615
Ensembl chr 3:49,468,713...49,535,618
JBrowse link
G DCN decorin ISO RGD PMID:16311904 RGD:1598497 NCBI chr12:91,140,484...91,182,817
Ensembl chr12:91,140,484...91,183,217
JBrowse link
G DDIT3 DNA damage inducible transcript 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25450231 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G DGKZ diacylglycerol kinase zeta EXP CTD Direct Evidence: therapeutic CTD PMID:17071729 NCBI chr11:46,332,926...46,380,554
Ensembl chr11:46,332,905...46,380,554
JBrowse link
G DVL1 dishevelled segment polarity protein 1 ISO RGD PMID:15256074 RGD:1580899 NCBI chr 1:1,335,278...1,349,418
Ensembl chr 1:1,335,276...1,349,418
JBrowse link
G DYRK1A dual specificity tyrosine phosphorylation regulated kinase 1A treatment ISO associated with heart failure; protein:increased expression, increased activity:heart left ventricle (rat) RGD PMID:26067684 RGD:11097969 NCBI chr21:37,365,573...37,526,358
Ensembl chr21:37,365,573...37,526,358
JBrowse link
G ECE1 endothelin converting enzyme 1 IEP RGD PMID:9607404 RGD:1580912 NCBI chr 1:21,217,250...21,345,504
Ensembl chr 1:21,217,247...21,345,572
JBrowse link
G EDN1 endothelin 1 severity IEP
ISO
protein:increased secretion:plasma (human)
mRNA:increased expression:heart left ventricle (rat)
RGD PMID:17893002 PMID:10573185 RGD:4144880, RGD:1580921 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194
JBrowse link
G EDN2 endothelin 2 ISO RGD PMID:10573185 RGD:1580921 NCBI chr 1:41,478,775...41,484,683
Ensembl chr 1:41,478,775...41,484,683
JBrowse link
G EDNRA endothelin receptor type A ISO RGD PMID:12524016 RGD:1580948 NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954
JBrowse link
G EDNRB endothelin receptor type B ISO RGD PMID:12524016 RGD:1580948 NCBI chr13:77,895,481...77,975,527
Ensembl chr13:77,895,481...77,975,529
JBrowse link
G EGLN1 egl-9 family hypoxia inducible factor 1 ISO RGD PMID:16765982 RGD:11252084 NCBI chr 1:231,363,756...231,422,287
Ensembl chr 1:231,363,751...231,422,287
JBrowse link
G EGLN3 egl-9 family hypoxia inducible factor 3 ISO RGD PMID:16765982 RGD:11252084 NCBI chr14:33,924,227...33,951,074
Ensembl chr14:33,924,227...34,462,774
JBrowse link
G EPAS1 endothelial PAS domain protein 1 ISO RGD PMID:15247145 PMID:18484163 RGD:1580977, RGD:5147886 NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697
JBrowse link
G EPHB1 EPH receptor B1 ameliorates ISO RGD PMID:28622474 RGD:329333030 NCBI chr 3:134,795,260...135,260,467
Ensembl chr 3:134,795,260...135,260,467
JBrowse link
G EPHX2 epoxide hydrolase 2 ISO RGD PMID:19716829 RGD:5688358 NCBI chr 8:27,491,143...27,548,626
Ensembl chr 8:27,490,781...27,545,564
JBrowse link
G EPO erythropoietin treatment IDA
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19337937 PMID:21415704 RGD:10400907 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700
JBrowse link
G EPOR erythropoietin receptor ISO RGD PMID:21415704 RGD:10400907 NCBI chr19:11,377,207...11,384,314
Ensembl chr19:11,377,207...11,384,342
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 treatment ISO RGD PMID:26892146 RGD:11522702 NCBI chr17:39,688,094...39,728,658
Ensembl chr17:39,687,914...39,730,426
JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 treatment ISO RGD PMID:26892146 RGD:11522702 NCBI chr 2:211,375,717...212,538,802
Ensembl chr 2:211,375,717...212,538,841
JBrowse link
G ESR1 estrogen receptor 1 susceptibility IEA
IAGP
EXP
ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:11894143 PMID:11919305 PMID:14600184 PMID:15133719 PMID:25741868 More... RGD:1331525 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G F10 coagulation factor X IAGP ClinVar Annotator: match by term: Myocardial infarction, decreased susceptibility to ClinVar PMID:10984565 PMID:12181036 PMID:25741868 NCBI chr13:113,122,799...113,149,529
Ensembl chr13:113,122,799...113,149,529
JBrowse link
G F12 coagulation factor XII susceptibility IAGP DNA:polymorphism:promoter:-46C>T(human) RGD PMID:16411408 RGD:11041803 NCBI chr 5:177,402,141...177,409,564
Ensembl chr 5:177,402,133...177,416,583
JBrowse link
G F13A1 coagulation factor XIII A chain IAGP
EXP
ClinVar Annotator: match by term: Myocardial infarction, protection against
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
RGD
PMID:8025280 PMID:9459313 PMID:9550516 PMID:10365735 PMID:10910914 More... RGD:1581022 NCBI chr 6:6,144,084...6,320,662
Ensembl chr 6:6,144,084...6,321,013
JBrowse link
G F2 coagulation factor II, thrombin susceptibility IAGP
EXP
DNA:polymorphism::20210G>A(human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:9292507 PMID:9531249 PMID:10027711 PMID:12480694 RGD:1581022 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G F3 coagulation factor III, tissue factor treatment ISO RGD PMID:21229253 RGD:11062083 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G F5 coagulation factor V susceptibility
no_association
IAGP
EXP
DNA:mutation:cds:1691G>A (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:9531249 PMID:15131548 PMID:10590188 RGD:11564335, RGD:11564337 NCBI chr 1:169,511,951...169,586,481
Ensembl chr 1:169,511,951...169,586,588
JBrowse link
G F7 coagulation factor VII susceptibility IAGP
EXP
IEP
ClinVar Annotator: match by term: F7-related condition
ClinVar Annotator: match by term: F7-related condition | ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Myocardial infarction, decreased susceptibility to
DNA:missense mutation, repeat:cds, intron:p.R353Q, (human)
protein:increased activity:plasma (human)
OMIM
ClinVar
CTD
RGD
PMID:1634227 PMID:2070047 PMID:6812354 PMID:7919338 PMID:7981691 More... RGD:1580374, RGD:11049521, RGD:2312409 NCBI chr13:113,105,788...113,120,685
Ensembl chr13:113,105,788...113,120,685
JBrowse link
G FABP3 fatty acid binding protein 3 IEP RGD PMID:8326460 RGD:1582401 NCBI chr 1:31,359,588...31,373,076
Ensembl chr 1:31,365,253...31,376,850
JBrowse link
G FGB fibrinogen beta chain IAGP
IEA
RGD
GAD
PMID:9437197 PMID:15118671 RGD:1580381, RGD:1331525 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807
JBrowse link
G FGF1 fibroblast growth factor 1 treatment IDA RGD PMID:24200746 RGD:10449026 NCBI chr 5:142,592,178...142,698,070
Ensembl chr 5:142,592,178...142,698,070
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 ISO RGD PMID:17439742 RGD:10402087 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ameliorates ISO RGD PMID:19358330 RGD:155663664 NCBI chr10:121,478,330...121,598,458
Ensembl chr10:121,478,332...121,598,458
JBrowse link
G FIS1 fission, mitochondrial 1 ISO protein:increased expression:plantaris (rat) RGD PMID:24427319 RGD:11557988 NCBI chr 7:101,239,472...101,245,081
Ensembl chr 7:101,239,458...101,252,316
JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 ISO RGD PMID:16714360 RGD:1601493 NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145
JBrowse link
G FLT3LG fms related receptor tyrosine kinase 3 ligand treatment ISO RGD PMID:24184252 RGD:11049498 NCBI chr19:49,474,215...49,486,231
Ensembl chr19:49,474,207...49,486,231
JBrowse link
G FN1 fibronectin 1 ISO protein:decreased expression:heart RGD PMID:19695229 RGD:2325720 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit ISO protein:increased expression:paraventricular nucleus hypothalamus, paraventricular nucleus thalamus RGD PMID:27601012 RGD:405649741 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase treatment ISO
IAGP
mRNA, protein:decreased expression:heart
DNA:SNP: :rs17817449 (human)
associated with type 2 diabetes mellitus;DNA:SNP:intron:rs9939609 (human)
RGD PMID:29997116 PMID:26772723 PMID:20031593 PMID:29997116 RGD:329812009, RGD:11555187, RGD:329901766, RGD:329812009 NCBI chr16:53,703,963...54,121,941
Ensembl chr16:53,701,692...54,158,512
JBrowse link
G FZD2 frizzled class receptor 2 ISO mRNA:increased expression:heart left ventricle RGD PMID:9142123 RGD:4107058 NCBI chr17:44,557,484...44,561,262
Ensembl chr17:44,557,484...44,561,262
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase treatment ISO RGD PMID:20462747 RGD:10449173 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572
JBrowse link
G GATA4 GATA binding protein 4 treatment ISO
EXP
CTD Direct Evidence: therapeutic CTD
RGD
PMID:20200331 PMID:23948075 RGD:7327215 NCBI chr 8:11,676,935...11,760,002
Ensembl chr 8:11,676,959...11,760,002
JBrowse link
G GATM glycine amidinotransferase ISO RGD PMID:31972362 RGD:329961305 NCBI chr15:45,361,124...45,402,227
Ensembl chr15:45,361,124...45,402,327
JBrowse link
G GCH1 GTP cyclohydrolase 1 treatment ISO RGD PMID:32782412 PMID:26192027 RGD:329961570, RGD:329970290 NCBI chr14:54,842,017...54,902,826
Ensembl chr14:54,842,008...54,902,826
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit IAGP
EXP
DNA:snp:promoter:c.-129C>T (human)
ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
RGD
PMID:12598062 PMID:12598062 RGD:1302515 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit susceptibility IAGP
EXP
ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
OMIM
CTD
PMID:12081989 PMID:12975258 NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456
JBrowse link
G GGT1 gamma-glutamyltransferase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19419996 NCBI chr22:24,583,750...24,628,996
Ensembl chr22:24,594,811...24,629,005
JBrowse link
G GH1 growth hormone 1 treatment IDA RGD PMID:12500159 RGD:11352745 NCBI chr17:63,917,203...63,918,839
Ensembl chr17:63,917,200...63,918,839
JBrowse link
G GHRH growth hormone releasing hormone treatment ISO RGD PMID:24373935 RGD:10401242 NCBI chr20:37,251,086...37,261,814
Ensembl chr20:37,251,086...37,261,819
JBrowse link
G GJA1 gap junction protein alpha 1 treatment ISO protein:decreased phosphorylation RGD PMID:22969867 PMID:29428663 PMID:22841862 RGD:7207261, RGD:13592597, RGD:7207262 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
JBrowse link
G GJA4 gap junction protein alpha 4 IAGP DNA:SNP:CDS:T allele of 1019C>T in Japanese men (p<0.001)
associated with coronary artery disease; DNA:SNP:CDS:C allele of 1019C>T, amino acid P319S (p = 0.0026) in a Swiss population
RGD PMID:12477941 PMID:16677656 PMID:15982495 RGD:1626626, RGD:1626615, RGD:1580400 NCBI chr 1:34,792,999...34,795,747
Ensembl chr 1:34,792,999...34,795,747
JBrowse link
G GJA5 gap junction protein alpha 5 treatment ISO RGD PMID:29428663 RGD:13592597 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
G GP1BA glycoprotein Ib platelet subunit alpha IAGP RGD PMID:15269835 RGD:1580432 NCBI chr17:4,932,277...4,935,023
Ensembl chr17:4,932,277...4,935,023
JBrowse link
G GP6 glycoprotein VI platelet sexual_dimorphism
treatment
no_association
susceptibility
onset
IAGP
IMP
DNA:missense mutation:CDS:c.13254T>C (p.S219P) (human)
human protein in a mouse model
DNA:missense mutation:CDS:c.13254T>C (p.S219P) (rs1613662) (human)
DNA:missense mutation:exon 7:c.645213C>T (p.T249A) (human)
DNA:SNP, missense mutation:promoter, CDS:c.-148C>T, c.13254T>C (p.S219P) (human)
RGD PMID:11571236 PMID:22814400 PMID:20723028 PMID:12417295 PMID:11571236 More... RGD:401793749, RGD:401824647, RGD:401794407, RGD:401793754, RGD:401793749, RGD:401793749 NCBI chr19:55,013,705...55,038,264
Ensembl chr19:55,013,705...55,038,264
JBrowse link
G GPT glutamic--pyruvic transaminase treatment ISO RGD PMID:32026788 RGD:401793703 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
JBrowse link
G GPX1 glutathione peroxidase 1 susceptibility IEP RGD PMID:14573732 RGD:1600662 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
JBrowse link
G GSK3B glycogen synthase kinase 3 beta treatment ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:16716347 PMID:16565311 RGD:10045368 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994
JBrowse link
G GSN gelsolin ameliorates IEP
ISO
protein:decreased expression:blood serum (human) RGD PMID:9142022 PMID:28622474 RGD:329333022, RGD:329333030 NCBI chr 9:121,201,483...121,332,842
Ensembl chr 9:121,207,794...121,332,843
JBrowse link
G GSR glutathione-disulfide reductase treatment ISO RGD PMID:25119867 RGD:10401898 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 IAGP ClinVar Annotator: match by term: Myocardial infarction, susceptibility to, 1 ClinVar PMID:24213632 NCBI chr 4:155,666,848...155,737,059
Ensembl chr 4:155,666,726...155,737,059
JBrowse link
G H19 H19 imprinted maternally expressed transcript ameliorates ISO RGD PMID:33389498 RGD:242905187 NCBI chr11:1,995,176...2,001,466
Ensembl chr11:1,995,166...2,004,552
JBrowse link
G HADH hydroxyacyl-CoA dehydrogenase ISO RGD PMID:11481570 RGD:2302229 NCBI chr 4:107,989,889...108,035,171
Ensembl chr 4:107,989,714...108,035,241
JBrowse link
G HAMP hepcidin antimicrobial peptide ISO mRNA:increased expression:heart RGD PMID:19615879 RGD:11041636 NCBI chr19:35,282,528...35,285,143
Ensembl chr19:35,280,716...35,285,143
JBrowse link
G HFE homeostatic iron regulator susceptibility
no_association
IAGP RGD PMID:10491370 PMID:12850485 RGD:1582697, RGD:1582672 NCBI chr 6:26,087,429...26,098,343
Ensembl chr 6:26,087,226...26,098,343
JBrowse link
G HGF hepatocyte growth factor treatment IEP
IDA
protein:increased expression:serum: RGD PMID:12419930 PMID:16570015 RGD:8548609, RGD:8548632 NCBI chr 7:81,699,010...81,770,047
Ensembl chr 7:81,699,010...81,770,438
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ameliorates
treatment
ISO
IMP
mRNA:increased expression:heart left ventricle
human gene in a rat model
RGD PMID:18484163 PMID:28622474 PMID:15247145 PMID:15999059 RGD:5147886, RGD:329333030, RGD:1580977, RGD:9068466 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G HMGB1 high mobility group box 1 treatment ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:21113057 PMID:23188125 RGD:10402174 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597
JBrowse link
G HMOX1 heme oxygenase 1 ISO RGD PMID:12392996 PMID:20925964 RGD:1598393, RGD:4145134 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HP haptoglobin susceptibility IAGP
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:16597321 PMID:17068284 PMID:17207726 PMID:3990081 PMID:2613263 RGD:1626360, RGD:1626354 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055
JBrowse link
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 ameliorates ISO RGD PMID:28522730 PMID:26465199 RGD:329902054, RGD:11087531 NCBI chr 1:209,686,179...209,734,929
Ensembl chr 1:209,686,178...209,734,949
JBrowse link
G HSD11B2 hydroxysteroid 11-beta dehydrogenase 2 ISO
EXP
mRNA:increased expression:heart
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:17587755 PMID:17587755 RGD:2308939 NCBI chr16:67,429,801...67,437,553
Ensembl chr16:67,430,652...67,437,553
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25450231 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 ISO RGD PMID:17202668 RGD:1624230 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737
JBrowse link
G ICAM1 intercellular adhesion molecule 1 treatment ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:10070497 PMID:23139358 RGD:8547733 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IFNA2 interferon alpha 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:3597002 NCBI chr 9:21,384,255...21,385,398
Ensembl chr 9:21,384,255...21,385,398
JBrowse link
G IGF1 insulin like growth factor 1 severity ISO
IAGP
mRNA, protein:increased expression:myocardium RGD PMID:19295919 PMID:16635594 RGD:2306696, RGD:1598421 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744
JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO mRNA,protein:increased expression:myocyte: RGD PMID:8682060 RGD:10046050 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530
JBrowse link
G IL10 interleukin 10 susceptibility IAGP
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:15883752 PMID:16310260 PMID:15466015 RGD:1598480 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL17A interleukin 17A ISO mRNA, protein:increased expression:heart left ventricle (rat) RGD PMID:23096364 RGD:9095344 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638
JBrowse link
G IL18 interleukin 18 ameliorates ISO RGD PMID:33389498 RGD:242905187 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
JBrowse link
G IL18BP interleukin 18 binding protein IDA RGD PMID:19805173 RGD:4889400 NCBI chr11:71,998,909...72,008,200
Ensembl chr11:71,998,613...72,007,315
JBrowse link
G IL1B interleukin 1 beta ameliorates ISO
EXP
CTD Direct Evidence: marker/mechanism
protein:increased expression:serum (rat)
CTD
RGD
PMID:11743230 PMID:15883752 PMID:16310260 PMID:23143013 PMID:33389498 More... RGD:7175553, RGD:242905187, RGD:7204425 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL1RN interleukin 1 receptor antagonist EXP CTD Direct Evidence: therapeutic CTD PMID:18474815 PMID:19005744 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016
JBrowse link
G IL4R interleukin 4 receptor ISO mRNA:increased expression:heart RGD PMID:10807530 RGD:4889985 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778
JBrowse link
G IL6 interleukin 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15883752 PMID:16310260 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G IL6R interleukin 6 receptor ISO RGD PMID:12123772 RGD:1625444 NCBI chr 1:154,405,343...154,469,450
Ensembl chr 1:154,405,193...154,469,450
JBrowse link
G INHBA inhibin subunit beta A ISO mRNA:increased expression:heart (rat)
mRNA:increased expression:myocardium (mouse)
RGD PMID:14993131 PMID:32427381 RGD:1580888, RGD:329849118 NCBI chr 7:41,685,114...41,705,406
Ensembl chr 7:41,667,168...41,705,834
JBrowse link
G INHBB inhibin subunit beta B ISO mRNA:increased expression:myocardium (mouse) RGD PMID:32427381 RGD:329849118 NCBI chr 2:120,346,136...120,351,803
Ensembl chr 2:120,346,136...120,351,803
JBrowse link
G ISL1 ISL LIM homeobox 1 ameliorates IDA
ISO
RGD PMID:29482621 PMID:22727192 RGD:243048463, RGD:243048464 NCBI chr 5:51,383,448...51,394,730
Ensembl chr 5:51,383,448...51,394,730
JBrowse link
G ITGA2 integrin subunit alpha 2 susceptibility
no_association
IAGP RGD PMID:16697311 PMID:10194421 PMID:15227729 RGD:1582296, RGD:1581029, RGD:1582294 NCBI chr 5:52,989,352...53,094,779
Ensembl chr 5:52,989,340...53,094,779
JBrowse link
G ITGA3 integrin subunit alpha 3 ISO protein:increased expression:myocardium (rat) RGD PMID:19041328 RGD:2325287 NCBI chr17:50,056,110...50,090,481
Ensembl chr17:50,055,968...50,090,481
JBrowse link
G ITGAM integrin subunit alpha M treatment ISO RGD PMID:29933226 RGD:329853753 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892
JBrowse link
G ITGB1 integrin subunit beta 1 treatment ISO RGD PMID:28367125 RGD:13602094 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792
JBrowse link
G ITGB3 integrin subunit beta 3 no_association
susceptibility
IAGP
EXP
DNA:polymorphism:exon:
ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
CTD Direct Evidence: marker/mechanism
associated with arteriosclerosis; DNA:polymorphism:exon
OMIM
ClinVar
CTD
RGD
PMID:2014236 PMID:7570918 PMID:8598867 PMID:8667943 PMID:8838346 More... RGD:5128498, RGD:5128481, RGD:5128476 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,827...47,313,743
JBrowse link
G ITIH4 inter-alpha-trypsin inhibitor heavy chain 4 IDA RGD PMID:10486281 RGD:1582334 NCBI chr 3:52,812,962...52,830,672
Ensembl chr 3:52,812,962...52,830,688
JBrowse link
G JAK2 Janus kinase 2 susceptibility ISO associated with Myocardial Reperfusion Injury RGD PMID:22749532 RGD:10403083 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948
JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 treatment ISO RGD PMID:23647964 RGD:7247426 NCBI chr17:70,169,532...70,180,044
Ensembl chr17:70,168,673...70,180,044
JBrowse link
G KCNK2 potassium two pore domain channel subfamily K member 2 ISO mRNA:decreased expression:heart left ventricle, epicardium, endocardium (rat) RGD PMID:21683547 RGD:9831182 NCBI chr 1:215,005,542...215,237,090
Ensembl chr 1:215,005,775...215,237,090
JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 susceptibility IAGP DNA:SNPs,haplotypes:introns:multiple RGD PMID:19644414 RGD:329969896 NCBI chr19:43,766,533...43,780,973
Ensembl chr19:43,766,533...43,780,976
JBrowse link
G KDM5B lysine demethylase 5B ameliorates ISO RGD PMID:36481938 RGD:329901769 NCBI chr 1:202,724,495...202,808,421
Ensembl chr 1:202,724,495...202,808,487
JBrowse link
G KDM6A lysine demethylase 6A ISO mRNA:increased expression:myocardium (rat) RGD PMID:30887465 RGD:151665136 NCBI chr  X:44,873,188...45,112,779
Ensembl chr  X:44,873,188...45,112,779
JBrowse link
G KDR kinase insert domain receptor treatment IDA
ISO
RGD PMID:16698275 PMID:25936512 RGD:1581717, RGD:126925214 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595
JBrowse link
G KIF6 kinesin family member 6 no_association
treatment
EXP
IAGP
CTD Direct Evidence: marker/mechanism
DNA:SNP: :p.W719R (rs20455) (human)
DNA:SNP: :rs20455 (human)
CTD
RGD
PMID:21943003 PMID:20927332 PMID:26997531 PMID:19371834 PMID:20403483 More... RGD:243048450, RGD:243048449, RGD:243048447, RGD:11097528, RGD:243048446 NCBI chr 6:39,329,990...39,725,408
Ensembl chr 6:39,329,990...39,725,408
JBrowse link
G KLF13 KLF transcription factor 13 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29122578 NCBI chr15:31,326,835...31,435,665
Ensembl chr15:31,326,835...31,435,665
JBrowse link
G KLK1 kallikrein 1 IAGP
EXP
CTD Direct Evidence: therapeutic CTD
RGD
PMID:12411458 PMID:17022964 RGD:1641799 NCBI chr19:50,819,146...50,823,787
Ensembl chr19:50,819,146...50,823,787
JBrowse link
G LAMP2 lysosomal associated membrane protein 2 ISO mRNA:increased expression:plantaris RGD PMID:24427319 RGD:11557988 NCBI chr  X:120,426,148...120,469,349
Ensembl chr  X:120,426,148...120,469,365
JBrowse link
G LCAT lecithin-cholesterol acyltransferase ISO RGD PMID:16640830 RGD:1581773 NCBI chr16:67,939,750...67,944,120
Ensembl chr16:67,939,750...67,944,131
JBrowse link
G LCN2 lipocalin 2 ameliorates ISO RGD PMID:27800610 RGD:126790572 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453
JBrowse link
G LDHA lactate dehydrogenase A EXP CTD Direct Evidence: marker/mechanism CTD PMID:3279722 NCBI chr11:18,394,563...18,408,425
Ensembl chr11:18,394,560...18,408,425
JBrowse link
G LDLR low density lipoprotein receptor IEA GAD PMID:15118671 RGD:1331525 NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820
JBrowse link
G LEFTY1 left-right determination factor 1 ameliorates ISO RGD PMID:33409963 RGD:401794430 NCBI chr 1:225,886,282...225,889,146
Ensembl chr 1:225,886,282...225,911,382
JBrowse link
G LGALS2 galectin 2 susceptibility IAGP
EXP
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
OMIM
CTD
ClinVar
RGD
PMID:15129282 PMID:15129282 RGD:1581852 NCBI chr22:37,570,248...37,580,087
Ensembl chr22:37,570,248...37,582,616
JBrowse link
G LGALS3 galectin 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29769800 NCBI chr14:55,129,252...55,145,430
Ensembl chr14:55,124,110...55,145,423
JBrowse link
G LINC01588 long intergenic non-protein coding RNA 1588 EXP CTD Direct Evidence: therapeutic CTD PMID:35258167 NCBI chr14:49,981,669...50,007,520
Ensembl chr14:49,927,571...50,105,102
JBrowse link
G LIPG lipase G, endothelial type susceptibility IAGP DNA:polymorphism: :584C>T (human) RGD PMID:17526978 RGD:1641818 NCBI chr18:49,561,479...49,599,185
Ensembl chr18:49,560,699...49,599,185
JBrowse link
G LOC100287329 uncharacterized LOC100287329 IAGP ClinVar Annotator: match by term: Myocardial infarction, susceptibility to ClinVar PMID:12426569 PMID:12746914 PMID:14681301 NCBI chr 6:31,559,571...31,572,703 JBrowse link
G LOC129930970 ATAC-STARR-seq lymphoblastoid silent region 1091 IAGP ClinVar Annotator: match by term: Myocardial infarction, susceptibility to ClinVar PMID:12081989 PMID:12975258 NCBI chr 1:93,909,514...93,909,753 JBrowse link
G LOX lysyl oxidase ISO RGD PMID:14553832 RGD:1581883 NCBI chr 5:122,063,195...122,078,259
Ensembl chr 5:122,063,195...122,078,413
JBrowse link
G LPA lipoprotein(a) IAGP DNA:SNP:CDS:rs3798220, g.160961137T>C, p.Ile1891Met RGD PMID:18775538 RGD:5509091 NCBI chr 6:160,531,482...160,664,275
Ensembl chr 6:160,531,482...160,664,275
JBrowse link
G LPL lipoprotein lipase susceptibility IAGP associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:SNP: :p.D9N (rs1801177) (human) RGD PMID:18823627 RGD:2313302 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259
JBrowse link
G LRP1 LDL receptor related protein 1 susceptibility IAGP RGD PMID:12402342 RGD:1581913 NCBI chr12:57,128,483...57,213,361
Ensembl chr12:57,128,483...57,213,361
JBrowse link
G LRP8 LDL receptor related protein 8 onset
susceptibility
no_association
IAGP
EXP
DNA:missense mutation:cds:p.R952Q (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Myocardial infarction, susceptibility to, 1
CTD
OMIM
ClinVar
RGD
PMID:17847002 PMID:17847002 PMID:18592168 RGD:2306124, RGD:2306125 NCBI chr 1:53,242,364...53,328,070
Ensembl chr 1:53,242,364...53,328,469
JBrowse link
G LRPAP1 LDL receptor related protein associated protein 1 susceptibility IAGP RGD PMID:12394648 RGD:1581922 NCBI chr 4:3,503,612...3,532,422
Ensembl chr 4:3,503,612...3,532,446
JBrowse link
G LTA lymphotoxin alpha no_association
susceptibility
severity
IAGP
EXP
ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
CTD Direct Evidence: marker/mechanism
DNA:SNP:exon:804C>A (p.T26N) (human)
ClinVar
OMIM
CTD
RGD
PMID:12426569 PMID:12746914 PMID:14681301 PMID:15129282 PMID:15266304 More... RGD:1581940, RGD:8548841, RGD:1580417 NCBI chr 6:31,560,610...31,574,324
Ensembl chr 6:31,572,054...31,574,324
JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha treatment ISO RGD PMID:20079142 RGD:11561913 NCBI chr20:34,546,844...34,560,345
Ensembl chr20:34,546,854...34,560,345
JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 treatment ISO RGD PMID:22635076 RGD:10412335 NCBI chr 6:136,557,046...136,793,091
Ensembl chr 6:136,557,046...136,793,097
JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 treatment ISO mRNA, protein:increased expression:myocardium (rat) RGD PMID:16183734 PMID:27121011 RGD:2298758, RGD:11073666 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO RGD PMID:15653762 RGD:1582282 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK14 mitogen-activated protein kinase 14 ameliorates ISO RGD PMID:33409963 RGD:401794430 NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,782...36,111,236
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 ameliorates ISO RGD PMID:28622474 RGD:329333030 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
JBrowse link
G MDH2 malate dehydrogenase 2 ISO RGD PMID:9753871 RGD:1582468 NCBI chr 7:76,048,106...76,067,508
Ensembl chr 7:76,048,051...76,067,508
JBrowse link
G MDK midkine ISO RGD PMID:9568069 RGD:1582488 NCBI chr11:46,380,784...46,383,837
Ensembl chr11:46,380,756...46,383,837
JBrowse link
G MEF2A myocyte enhancer factor 2A TAS RGD PMID:15811259 RGD:1580548 NCBI chr15:99,565,417...99,716,488
Ensembl chr15:99,565,417...99,716,488
JBrowse link
G MEF2C myocyte enhancer factor 2C treatment ISO RGD PMID:23948075 RGD:7327215 NCBI chr 5:88,717,117...88,904,105
Ensembl chr 5:88,717,117...88,904,257
JBrowse link
G MEOX2 mesenchyme homeobox 2 ISO protein:decreased expression:heart (rat) RGD PMID:24155330 RGD:155882536 NCBI chr 7:15,611,212...15,686,683
Ensembl chr 7:15,611,212...15,686,683
JBrowse link
G MESP1 mesoderm posterior bHLH transcription factor 1 treatment IMP human gene and cell line in a rat model RGD PMID:32550911 RGD:242905196 NCBI chr15:89,732,446...89,751,249
Ensembl chr15:89,749,875...89,751,249
JBrowse link
G MFF mitochondrial fission factor treatment ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:23867156 PMID:23867156 RGD:12879458 NCBI chr 2:227,325,251...227,357,836
Ensembl chr 2:227,325,151...227,357,833
JBrowse link
G MFN2 mitofusin 2 treatment ISO RGD PMID:20886221 RGD:12738232 NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211
JBrowse link
G MGP matrix Gla protein susceptibility IAGP RGD PMID:11073842 RGD:1582503 NCBI chr12:14,880,864...14,885,854
Ensembl chr12:14,880,864...14,885,857
JBrowse link
G MIA3 MIA SH3 domain ER export factor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19198609 NCBI chr 1:222,618,097...222,668,007
Ensembl chr 1:222,618,097...222,668,007
JBrowse link
G MIAT myocardial infarction associated transcript susceptibility EXP
IAGP
CTD Direct Evidence: marker/mechanism CTD
OMIM
PMID:17066261 NCBI chr22:26,646,429...26,676,478
Ensembl chr22:26,646,411...26,676,475
JBrowse link
G MIF macrophage migration inhibitory factor ISO
IEP
mRNA, protein:increased expression:myocardium
protein:increased expression:plasma
RGD PMID:12704210 PMID:11589847 RGD:1642003, RGD:1642008 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227
JBrowse link
G MIR125B2 microRNA 125b-2 EXP CTD Direct Evidence: therapeutic CTD PMID:29122578 NCBI chr21:16,590,237...16,590,325
Ensembl chr21:16,590,237...16,590,325
JBrowse link
G MIR143 microRNA 143 ISO RNA:increased expression:myocardium:
RNA:increased expression:plasma, left ventricle:
RGD PMID:28887629 PMID:29728596 RGD:155882580, RGD:155882581 NCBI chr 5:149,428,918...149,429,023
Ensembl chr 5:149,428,918...149,429,023
JBrowse link
G MIR145 microRNA 145 treatment
ameliorates
EXP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:29956747 PMID:30146700 PMID:32890431 RGD:155260296, RGD:155260294 NCBI chr 5:149,430,646...149,430,733
Ensembl chr 5:149,430,646...149,430,733
JBrowse link
G MIR155 microRNA 155 treatment ISO RGD PMID:31207208 RGD:21066347 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044
JBrowse link
G MIR208A microRNA 208a treatment ISO miRNA:increased expression:heart RGD PMID:26688617 PMID:26861724 RGD:11536862, RGD:242905213 NCBI chr14:23,388,596...23,388,666
Ensembl chr14:23,388,596...23,388,666
JBrowse link
G MIR223 microRNA 223 ISO RNA:increased expression:heart RGD PMID:29608885 RGD:21408565 NCBI chr  X:66,018,870...66,018,979
Ensembl chr  X:66,018,870...66,018,979
JBrowse link
G MIR25 microRNA 25 ISO RNA:increased expression:myocardium: RGD PMID:28887629 RGD:155882580 NCBI chr 7:100,093,560...100,093,643
Ensembl chr 7:100,093,560...100,093,643
JBrowse link
G MIR30A microRNA 30a treatment ISO RGD PMID:29849775 RGD:35673318 NCBI chr 6:71,403,551...71,403,621
Ensembl chr 6:71,403,551...71,403,621
JBrowse link
G MIR30C1 microRNA 30c-1 EXP CTD Direct Evidence: therapeutic CTD PMID:34217758 NCBI chr 1:40,757,284...40,757,372
Ensembl chr 1:40,757,284...40,757,372
JBrowse link
G MIR30E microRNA 30e ISO miRNA:decreased expression:heart (rat) RGD PMID:25950484 RGD:11541106 NCBI chr 1:40,754,355...40,754,446
Ensembl chr 1:40,754,355...40,754,446
JBrowse link
G MIR320A microRNA 320a treatment ISO RGD PMID:19380620 RGD:155882541 NCBI chr 8:22,244,966...22,245,037
Ensembl chr 8:22,244,962...22,245,043
JBrowse link
G MIR423 microRNA 423 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24253456 NCBI chr17:30,117,079...30,117,172
Ensembl chr17:30,117,079...30,117,172
JBrowse link
G MIR761 microRNA 761 EXP CTD Direct Evidence: therapeutic CTD PMID:23867156 NCBI chr 1:51,836,344...51,836,402
Ensembl chr 1:51,836,344...51,836,402
JBrowse link
G MLXIPL MLX interacting protein like susceptibility IAGP DNA:SNP:cd: C771G, p.Q241H (rs3812316) (human) RGD PMID:24448738 RGD:401799621 NCBI chr 7:73,593,202...73,647,907
Ensembl chr 7:73,593,194...73,624,543
JBrowse link
G MMP1 matrix metallopeptidase 1 susceptibility IAGP
ISO
IMP
IDA
associated with Coronary Artery Disease; DNA:snps, haplotype:promoter:g.-519A>G, g.-340T>C (human)
protein:increased expression, increased activity:heart left ventricle (rat)
human gene in rat model
RGD PMID:16210545 PMID:8531210 PMID:11179039 PMID:19797822 PMID:15009768 RGD:1582520, RGD:7207198, RGD:7207136, RGD:7207135, RGD:1582535 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160
JBrowse link
G MMP13 matrix metallopeptidase 13 ISO RGD PMID:15782494 RGD:1582556 NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732
JBrowse link
G MMP14 matrix metallopeptidase 14 IDA RGD PMID:16461815 RGD:1582569 NCBI chr14:22,836,585...22,847,758
Ensembl chr14:22,836,560...22,849,041
JBrowse link
G MMP2 matrix metallopeptidase 2 ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:16310260 PMID:24358288 PMID:10773235 PMID:11179039 RGD:1582587, RGD:7207136 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G MMP3 matrix metallopeptidase 3 IAGP RGD PMID:15467919 RGD:1580551 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609
JBrowse link
G MMP7 matrix metallopeptidase 7 ISO RGD PMID:16769909 RGD:1582373 NCBI chr11:102,520,508...102,530,747
Ensembl chr11:102,520,508...102,530,750
JBrowse link
G MMP9 matrix metallopeptidase 9 susceptibility ISO
EXP
IAGP
IEP
CTD Direct Evidence: marker/mechanism
protein:increased expression:heart left ventricle
protein:increased expression, increased activity:heart left ventricle (rat)
DNA:snps:promoter, exon:g.-1562C>T, p.R279Q (rs3918242, rs2664538) (human)
protein:increased expression:coronary artery, plasma (human)
CTD
RGD
PMID:16310260 PMID:24358288 PMID:14729404 PMID:25520329 PMID:8531210 More... RGD:1582639, RGD:13204799, RGD:7207198, RGD:7207049, RGD:1582653, RGD:1582645 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G MSTN myostatin ISO mRNA:decreased expression:myocardium (mouse) RGD PMID:32427381 RGD:329849118 NCBI chr 2:190,055,700...190,062,729
Ensembl chr 2:190,055,700...190,062,729
JBrowse link
G MT-ND2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 IAGP DNA:missense mutation: :m.5178C>A (p.L237M) (human) RGD PMID:15262184 RGD:1581054 NCBI chr MT:4,470...5,511
Ensembl chr MT:4,470...5,511
JBrowse link
G MTHFR methylenetetrahydrofolate reductase susceptibility IAGP associated with Kidney Failure, Chronic; DNA:transition:cds:g.677C>T rs1801133 (human)
DNA:SNP: :677C>T (human)
RGD PMID:19272686 PMID:10090925 RGD:6893548, RGD:10449412 NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455
JBrowse link
G MTOR mechanistic target of rapamycin kinase treatment ISO protein:decreased serine phosphorylation:heart
associated with Diabetes Mellitus, Experimental
RGD PMID:20352476 PMID:23773982 RGD:10041035, RGD:10041040 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556
JBrowse link
G MYH6 myosin heavy chain 6 ISO RGD PMID:15090263 RGD:11565830 NCBI chr14:23,381,987...23,408,273
Ensembl chr14:23,381,982...23,408,273
JBrowse link
G MYH7 myosin heavy chain 7 ISO
EXP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:11743230 PMID:15090263 RGD:11565830 NCBI chr14:23,412,740...23,435,660
Ensembl chr14:23,412,740...23,435,660
JBrowse link
G NCAM1 neural cell adhesion molecule 1 ISO mRNA, protein:increased expression:heart
protein:alternative form, increased expression:myocardium
RGD PMID:19853610 PMID:23462508 RGD:2325979, RGD:40924663 NCBI chr11:112,961,420...113,278,436
Ensembl chr11:112,961,275...113,278,436
JBrowse link
G NDUFB5 NADH:ubiquinone oxidoreductase subunit B5 treatment ISO RGD PMID:24692845 RGD:13801194 NCBI chr 3:179,604,794...179,627,647
Ensembl chr 3:179,604,690...179,627,647
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 treatment ISO RGD PMID:23290949 PMID:24915518 RGD:10412734, RGD:10412738 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
JBrowse link
G NFKBIA NFKB inhibitor alpha treatment ISO RGD PMID:19616538 RGD:10413879 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
JBrowse link
G NGF nerve growth factor treatment IEP
IMP
protein:increased expression:myocardium RGD PMID:20360245 PMID:20360245 RGD:405100231, RGD:405100231 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770
JBrowse link
G NLK nemo like kinase ISO mRNA, protein:decreased expression:heart RGD PMID:26861724 RGD:242905213 NCBI chr17:28,042,677...28,206,074
Ensembl chr17:28,041,737...28,196,381
JBrowse link
G NLRP3 NLR family pyrin domain containing 3 ameliorates ISO RGD PMID:33389498 RGD:242905187 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,332,331...247,449,108
JBrowse link
G NONO non-POU domain containing octamer binding ameliorates ISO RGD PMID:35247074 RGD:155882458 NCBI chr  X:71,283,635...71,301,168
Ensembl chr  X:71,254,814...71,301,522
JBrowse link
G NOS2 nitric oxide synthase 2 treatment EXP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:10090345 PMID:11489778 PMID:26192027 RGD:329970290 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NOS3 nitric oxide synthase 3 susceptibility
treatment
IAGP
EXP
ISO
IMP
DNA:repeats:intron
CTD Direct Evidence: marker/mechanism
protein:decreased expression:aorta (rat)
human gene in rat model
DNA:duplication:intron:IVS4?-?+27 (human)
CTD
RGD
PMID:10510054 PMID:16337503 PMID:10531147 PMID:29311930 PMID:28980197 More... RGD:5128481, RGD:13503346, RGD:13450930, RGD:7771563, RGD:7771561, RGD:1580283, RGD:1580284 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G NPM1 nucleophosmin 1 ISO protein:increased expression:cardiomyocyte: RGD PMID:21444791 RGD:11535018 NCBI chr 5:171,387,116...171,410,900
Ensembl chr 5:171,387,116...171,411,810
JBrowse link
G NPPA natriuretic peptide A IAGP
EXP
ISO
DNA:snp:cds:c.2238T>C (human)
CTD Direct Evidence: marker/mechanism|therapeutic
CTD
RGD
PMID:9527094 PMID:11743230 PMID:12514664 PMID:16087130 RGD:1579982, RGD:1580000 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345
JBrowse link
G NPPB natriuretic peptide B ISO
IDA
RGD PMID:19858735 PMID:17639095 PMID:17256064 RGD:2324680, RGD:7247724, RGD:1642266 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945
JBrowse link
G NPR1 natriuretic peptide receptor 1 susceptibility IAGP DNA:missense mutation:cds:p.M341I (human) RGD PMID:14646971 RGD:1580174 NCBI chr 1:153,678,688...153,693,992
Ensembl chr 1:153,678,688...153,693,992
JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 susceptibility IAGP DNA:SNPs, haplotype:promoter:c.-115G>A, c.-840C>A (rs12221497, rs61896015) (human) RGD PMID:21903943 RGD:401842365 NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033
JBrowse link
G NR3C2 nuclear receptor subfamily 3 group C member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16413583 PMID:17587755 NCBI chr 4:148,078,764...148,445,508
Ensembl chr 4:148,078,762...148,444,698
JBrowse link
G NRG1 neuregulin 1 treatment IDA
ISO
RGD PMID:24200746 PMID:26892146 PMID:27993643 RGD:10449026, RGD:11522702, RGD:405145704 NCBI chr 8:31,639,245...32,774,046
Ensembl chr 8:31,639,222...32,855,666
JBrowse link
G NRIP1 nuclear receptor interacting protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22503866 NCBI chr21:14,961,235...15,065,936
Ensembl chr21:14,961,235...15,065,936
JBrowse link
G OLR1 oxidized low density lipoprotein receptor 1 susceptibility IAGP
EXP
DNA:missense mutation:cds:p.K167N (human)
ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
OMIM
CTD
RGD
PMID:12646194 PMID:12810610 PMID:14684693 PMID:25741868 PMID:12646194 RGD:1580996 NCBI chr12:10,158,301...10,176,266
Ensembl chr12:10,158,301...10,172,138
JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase treatment ISO RGD PMID:20886221 RGD:12738232 NCBI chr 3:193,593,208...193,697,811
Ensembl chr 3:193,593,144...193,697,811
JBrowse link
G OPRD1 opioid receptor delta 1 ISO RGD PMID:12798419 PMID:15076225 RGD:2316587, RGD:9831425 NCBI chr 1:28,812,170...28,871,267
Ensembl chr 1:28,812,170...28,871,267
JBrowse link
G OPRK1 opioid receptor kappa 1 ISO RGD PMID:15076225 RGD:9831425 NCBI chr 8:53,225,724...53,251,637
Ensembl chr 8:53,225,724...53,251,637
JBrowse link
G P2RY12 purinergic receptor P2Y12 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19334620 NCBI chr 3:151,336,843...151,384,753
Ensembl chr 3:151,336,843...151,384,753
JBrowse link
G PAPPA pappalysin 1 susceptibility IAGP
EXP
DNA:polymorphism:intron
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:11586954 PMID:17700210 RGD:1642324 NCBI chr 9:116,153,791...116,402,321
Ensembl chr 9:116,153,791...116,402,321
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO protein:altered processing:left ventricle (mouse) RGD PMID:21282286 RGD:5684012 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 IAGP DNA:SNP:intron: (rs6080699) (human) RGD PMID:20036365 RGD:6483554 NCBI chr20:17,226,107...17,484,578
Ensembl chr20:17,226,107...17,484,578
JBrowse link
G PDE3A phosphodiesterase 3A EXP CTD Direct Evidence: marker/mechanism CTD PMID:19027736 NCBI chr12:20,368,537...20,688,583
Ensembl chr12:20,368,537...20,688,583
JBrowse link
G PDE5A phosphodiesterase 5A ISO RGD PMID:17339532 RGD:2314468 NCBI chr 4:119,494,403...119,628,804
Ensembl chr 4:119,494,397...119,628,804
JBrowse link
G PDGFD platelet derived growth factor D ISO mRNA,protein:altered expression:myocardium: RGD PMID:21767547 RGD:9854703 NCBI chr11:103,907,189...104,164,147
Ensembl chr11:103,907,189...104,164,379
JBrowse link
G PEBP1 phosphatidylethanolamine binding protein 1 ISO protein:decreased expression:right heart ventricle, ventricular septum RGD PMID:17089028 RGD:2302667 NCBI chr12:118,136,124...118,145,584
Ensembl chr12:118,136,124...118,145,584
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 onset
no_association
IAGP DNA:polymorphisms: :p.N563S, p.G670R (human)
DNA:missense mutation:cds:p.R643G (human)
DNA:missense mutations:cds:p.L125V, p.S563N (human)
RGD PMID:11795274 PMID:15488875 PMID:15265022 RGD:2311656, RGD:6771224, RGD:1581009 NCBI chr17:64,319,415...64,390,860
Ensembl chr17:64,319,415...64,413,776
JBrowse link
G PGF placental growth factor ISO
IDA
RGD PMID:20649603 PMID:21329947 PMID:22114497 RGD:6483584, RGD:6483777, RGD:6483773 NCBI chr14:74,941,830...74,955,764
Ensembl chr14:74,941,834...74,955,626
JBrowse link
G PHACTR1 phosphatase and actin regulator 1 susceptibility
severity
no_association
EXP
IAGP
IEP
ISO
CTD Direct Evidence: marker/mechanism
DNA:SNP:intron: (rs9369640) (human)
DNA:SNPs:multiple (human)
DNA:SNP:intron:(rs12526453) (human)
mRNA:increased expression:peripheral blood mononuclear cells (human)
DNA:SNPs:intron 3: (rs9349379, rs2026458, rs2876300) (human)
DNA:SNP:intron:g.13035530G>C (rs12526453) (human)
mRNA, protein:decreased expression:heart left ventricle (rat)
CTD
RGD
PMID:19198609 PMID:26098115 PMID:25738804 PMID:25838425 PMID:26086777 More... RGD:11052994, RGD:11052493, RGD:11056926, RGD:401900171, RGD:401900171, RGD:401851907, RGD:11053274 NCBI chr 6:12,716,767...13,287,837
Ensembl chr 6:12,716,312...13,290,446
JBrowse link
G PHLDA3 pleckstrin homology like domain family A member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34351043 NCBI chr 1:201,464,278...201,469,188
Ensembl chr 1:201,464,278...201,469,237
JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:20056919 RGD:6482688 NCBI chr 7:106,865,282...106,908,980
Ensembl chr 7:106,865,278...106,908,980
JBrowse link
G PLA2G7 phospholipase A2 group VII IEP protein:decreased expression:serum RGD PMID:19644070 RGD:6482786 NCBI chr 6:46,704,201...46,735,721
Ensembl chr 6:46,704,201...46,735,693
JBrowse link
G PLAT plasminogen activator, tissue type treatment IAGP
EXP
IDA
DNA:snp:enhancer:g.-7351C>T (human)
CTD Direct Evidence: therapeutic
CTD
RGD
PMID:1430592 PMID:1492007 PMID:1898952 PMID:1899364 PMID:1900011 More... RGD:1580881, RGD:11541077 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
JBrowse link
G PLAU plasminogen activator, urokinase IAGP
EXP
IMP
ISO
DNA:SNP:3' utr:c.*141C>T (rs4065) (human)
CTD Direct Evidence: marker/mechanism|therapeutic
mRNA, protein:increased expression:myocardium
CTD
RGD
PMID:1908371 PMID:2174952 PMID:2382605 PMID:3068399 PMID:3984876 More... RGD:6484126, RGD:6484145, RGD:6484133 NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496
JBrowse link
G PLAUR plasminogen activator, urokinase receptor IEP
ISO
mRNA, protein:increased expression:myocardium RGD PMID:12393744 PMID:20952728 RGD:1580897, RGD:6484133 NCBI chr19:43,646,095...43,670,169
Ensembl chr19:43,646,095...43,670,547
JBrowse link
G PLCB1 phospholipase C beta 1 ISO protein:increased expression:heart RGD PMID:9521338 RGD:2314514 NCBI chr20:8,132,266...8,884,900
Ensembl chr20:8,077,251...8,968,360
JBrowse link
G PLCB3 phospholipase C beta 3 ISO protein:increased expression:heart RGD PMID:9521338 RGD:2314514 NCBI chr11:64,251,530...64,269,452
Ensembl chr11:64,251,530...64,269,150
JBrowse link
G PLN phospholamban treatment ISO
EXP
protein:decreased expression:heart left ventricle (rat)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16026515 PMID:16162791 PMID:23781262 PMID:26067684 RGD:7327176, RGD:11097969 NCBI chr 6:118,548,296...118,561,716
Ensembl chr 6:118,548,296...118,561,716
JBrowse link
G PON1 paraoxonase 1 IAGP RGD PMID:10978258 PMID:10610741 RGD:1580202, RGD:1580198 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
JBrowse link
G POSTN periostin ISO protein:increased expression:heart: RGD PMID:24212842 RGD:10041024 NCBI chr13:37,562,585...37,598,768
Ensembl chr13:37,562,583...37,598,844
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha IAGP DNA:SNP:intron:rs4253623, minor allele associated with increased risk RGD PMID:18549840 RGD:5562819 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
JBrowse link
G PPARGC1A PPARG coactivator 1 alpha IEP
EXP
ISO
CTD Direct Evidence: marker/mechanism
protein:decreased expression:heart
CTD
RGD
PMID:22503866 PMID:22087236 PMID:22503866 RGD:6484266, RGD:7242181 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089
JBrowse link
G PRKCE protein kinase C epsilon EXP
ISO
CTD Direct Evidence: therapeutic
RNA:decreased expression:myocardium:
CTD
RGD
PMID:16782078 PMID:28887629 RGD:155882580 NCBI chr 2:45,651,279...46,187,990
Ensembl chr 2:45,651,345...46,187,990
JBrowse link
G PRKD1 protein kinase D1 treatment ISO RGD PMID:26064267 RGD:289474908 NCBI chr14:29,576,479...29,927,847
Ensembl chr14:29,576,479...30,191,898
JBrowse link
G PROC protein C, inactivator of coagulation factors Va and VIIIa IEP RGD PMID:10936861 RGD:11100014 NCBI chr 2:127,418,427...127,429,242
Ensembl chr 2:127,418,427...127,429,242
JBrowse link
G PRORP-PSMA6 PRORP-PSMA6 readthrough IAGP ClinVar Annotator: match by term: Myocardial infarction, susceptibility to ClinVar PMID:16845397 PMID:19282875 PMID:25741868 NCBI chr14:35,121,839...35,317,471 JBrowse link
G PSMA6 proteasome 20S subunit alpha 6 susceptibility IAGP
EXP
ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
OMIM
CTD
PMID:16845397 PMID:19282875 PMID:25741868 NCBI chr14:35,278,558...35,317,493
Ensembl chr14:35,278,633...35,317,493
JBrowse link
G PTGIS prostaglandin I2 synthase susceptibility IAGP DNA:SNP::1117C>A (human)
DNA:silent mutation:exon 8:1117C>A (human)
DNA:SNP:CDS: (rs5629) (human)
RGD PMID:19040046 PMID:12040339 PMID:19327107 PMID:19046748 RGD:401901147, RGD:401901268, RGD:401901155, RGD:2313891 NCBI chr20:49,503,874...49,568,137
Ensembl chr20:49,503,874...49,568,137
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 IAGP RGD PMID:15138244 RGD:1581289 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G PTN pleiotrophin ISO protein:increased expression:myocardium (rat) RGD PMID:17925408 RGD:10044023 NCBI chr 7:137,227,341...137,343,733
Ensembl chr 7:137,227,341...137,343,774
JBrowse link
G RAD50 RAD50 double strand break repair protein treatment ISO RGD PMID:15623426 RGD:9831390 NCBI chr 5:132,556,977...132,646,349
Ensembl chr 5:132,556,019...132,646,349
JBrowse link
G RANBP1 RAN binding protein 1 ISO protein:decreased expression:heart ventricle, cytoplasm (rat) RGD PMID:25341891 RGD:9835001 NCBI chr22:20,116,104...20,127,355
Ensembl chr22:20,115,938...20,127,355
JBrowse link
G RBP4 retinol binding protein 4 IEP protein:increased expression:blood serum (human) RGD PMID:25142320 RGD:329845867 NCBI chr10:93,591,694...93,601,744
Ensembl chr10:93,591,687...93,601,744
JBrowse link
G REG1A regenerating family member 1 alpha ISO mRNA:increased expression:heart left ventricle (rat) RGD PMID:15778284 RGD:9850130 NCBI chr 2:79,120,488...79,123,409
Ensembl chr 2:79,120,362...79,123,409
JBrowse link
G REN renin susceptibility IEP
EXP
associated with Hypertension; protein:increased activity:plasma (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:1668233 PMID:1759997 RGD:6892687 NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324
JBrowse link
G RETN resistin IEP protein:increased expression:plasma RGD PMID:18997620 RGD:7207152 NCBI chr19:7,669,049...7,670,455
Ensembl chr19:7,669,049...7,670,455
JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 ISO protein:increased threonine phosphorylation:heart left ventricle RGD PMID:16540832 RGD:1642998 NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574
JBrowse link
G RYR1 ryanodine receptor 1 ISO protein:hyperphosphorylation:extensor digitorum longus: RGD PMID:12824280 RGD:329813076 NCBI chr19:38,433,691...38,587,564
Ensembl chr19:38,433,691...38,595,273
JBrowse link
G S100B S100 calcium binding protein B ISO
EXP
mRNA, protein:increased expression:left ventricle myocardium, plasma
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:9788975 PMID:19910580 RGD:2325647 NCBI chr21:46,598,604...46,605,082
Ensembl chr21:46,598,604...46,605,208
JBrowse link
G SDC1 syndecan 1 ISO mRNA:increased expression:myocardium RGD PMID:9237025 RGD:2311712 NCBI chr 2:20,200,797...20,225,475
Ensembl chr 2:20,200,797...20,225,433
JBrowse link
G SDC4 syndecan 4 IEP protein:increased expression:plasma RGD PMID:11372670 RGD:2312328 NCBI chr20:45,325,288...45,348,424
Ensembl chr20:45,325,288...45,348,424
JBrowse link
G SELL selectin L EXP CTD Direct Evidence: marker/mechanism CTD PMID:10070497 NCBI chr 1:169,690,667...169,711,620
Ensembl chr 1:169,690,665...169,711,702
JBrowse link
G SELP selectin P susceptibility IEP
ISO
IAGP
associated with Hypertension;protein:increased expression:plasma
protein:increased expression:serum
DNA:polymorphisms, haplotypes:cds:p.S290N, p.N562D, p.T715P (human)
RGD PMID:17391113 PMID:21162967 PMID:21567088 PMID:12165563 RGD:2312304, RGD:6219003, RGD:6218991, RGD:1580075 NCBI chr 1:169,588,849...169,630,124
Ensembl chr 1:169,588,849...169,630,193
JBrowse link
G SERPINE1 serpin family E member 1 susceptibility IAGP
ISO
DNA:deletion:promoter:g.-676_-674delG (human) RGD PMID:12477941 PMID:16053971 RGD:1626626, RGD:8547882 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
JBrowse link
G SFRP2 secreted frizzled related protein 2 ISO RGD PMID:19109969 PMID:19079247 RGD:4107088, RGD:155883169 NCBI chr 4:153,780,591...153,789,083
Ensembl chr 4:153,780,591...153,789,083
JBrowse link
G SH2B3 SH2B adaptor protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19198610 NCBI chr12:111,404,730...111,451,623
Ensembl chr12:111,405,923...111,451,623
JBrowse link
G SHH sonic hedgehog signaling molecule treatment ISO RGD PMID:20052412 RGD:12879408 NCBI chr 7:155,799,980...155,812,463
Ensembl chr 7:155,799,980...155,812,463
JBrowse link
G SIRT1 sirtuin 1 ISO protein:altered localization:nucleus RGD PMID:20089851 RGD:2316169 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
JBrowse link
G SIRT3 sirtuin 3 treatment ISO RGD PMID:24471974 RGD:9586050 NCBI chr11:215,030...236,931
Ensembl chr11:215,030...236,931
JBrowse link
G SLC27A1 solute carrier family 27 member 1 ISO protein:decreased expression:heart RGD PMID:17034771 RGD:1642800 NCBI chr19:17,468,767...17,506,168
Ensembl chr19:17,468,769...17,506,168
JBrowse link
G SLC27A6 solute carrier family 27 member 6 ISO protein:decreased expression:heart RGD PMID:17034771 RGD:1642800 NCBI chr 5:128,965,488...129,033,635
Ensembl chr 5:128,538,013...129,033,642
JBrowse link
G SLPI secretory leukocyte peptidase inhibitor treatment ISO RGD PMID:23361363 RGD:9999400 NCBI chr20:45,252,239...45,254,564
Ensembl chr20:45,252,239...45,254,564
JBrowse link
G SMAD2 SMAD family member 2 treatment
ameliorates
ISO RGD PMID:11087260 PMID:33409963 RGD:12903276, RGD:401794430 NCBI chr18:47,808,957...47,930,872
Ensembl chr18:47,808,957...47,931,146
JBrowse link
G SMAD3 SMAD family member 3 ameliorates ISO RGD PMID:33409963 RGD:401794430 NCBI chr15:67,065,602...67,195,169
Ensembl chr15:67,063,763...67,195,173
JBrowse link
G SMAD4 SMAD family member 4 treatment ISO RGD PMID:11087260 RGD:12903276 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,528...51,085,045
JBrowse link
G SOCS1 suppressor of cytokine signaling 1 ISO protein:increased expression:heart RGD PMID:16377761 RGD:2298918 NCBI chr16:11,254,417...11,256,204
Ensembl chr16:11,254,417...11,256,204
JBrowse link
G SOD1 superoxide dismutase 1 treatment ISO
EXP
IMP
CTD Direct Evidence: therapeutic
human gene in a rat model
CTD
RGD
PMID:21600015 PMID:11864929 PMID:22006090 RGD:1581222, RGD:8655953 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
JBrowse link
G SOD2 superoxide dismutase 2 IEP
EXP
ISO
CTD Direct Evidence: therapeutic CTD
RGD
PMID:12160945 PMID:2313102 PMID:9250167 PMID:14575298 RGD:1580840, RGD:1580839, RGD:1581148 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SOD3 superoxide dismutase 3 IDA
IEP
RGD PMID:14592844 PMID:14592844 RGD:1580841, RGD:1580841 NCBI chr 4:24,795,573...24,800,842
Ensembl chr 4:24,789,912...24,800,842
JBrowse link
G SPARC secreted protein acidic and cysteine rich ISO mRNA:increased expression:heart RGD PMID:12826287 RGD:2300056 NCBI chr 5:151,661,096...151,686,915
Ensembl chr 5:151,661,096...151,686,975
JBrowse link
G SPP1 secreted phosphoprotein 1 IDA
ISO
RGD PMID:12939547 PMID:14500723 RGD:1581386, RGD:1581325 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532
JBrowse link
G SRSF1 serine and arginine rich splicing factor 1 treatment ISO protein:increased phosphorylation:heart left ventricle(rat) RGD PMID:26067684 RGD:11097969 NCBI chr17:57,989,038...58,007,246
Ensembl chr17:58,000,919...58,007,346
JBrowse link
G TBX3 T-box transcription factor 3 ISO RGD PMID:19341743 RGD:5132891 NCBI chr12:114,670,255...114,684,175
Ensembl chr12:114,670,255...114,684,175
JBrowse link
G TBX5 T-box transcription factor 5 treatment ISO RGD PMID:23948075 RGD:7327215 NCBI chr12:114,353,911...114,408,442
Ensembl chr12:114,353,911...114,408,442
JBrowse link
G TEK TEK receptor tyrosine kinase ISO protein:increased expression:ventricle myocardium RGD PMID:16714360 RGD:1601493 NCBI chr 9:27,109,141...27,230,178
Ensembl chr 9:27,109,141...27,230,174
JBrowse link
G TFPI tissue factor pathway inhibitor treatment IDA
ISO
IEP
mRNA,protein:increased expression:heart: RGD PMID:15630488 PMID:21229253 PMID:14656922 RGD:11060131, RGD:11062083, RGD:11060139 NCBI chr 2:187,464,230...187,554,435
Ensembl chr 2:187,464,230...187,565,760
JBrowse link
G TGFB1 transforming growth factor beta 1 susceptibility IAGP
EXP
ISO
IEA
associated with Coronary Disease;DNA:polymorphism:promoter:-509C>T (human)
CTD Direct Evidence: marker/mechanism
mRNA,protein:increased expression:heart:
CTD
RGD
PMID:16310260 PMID:16543493 PMID:27121011 PMID:15118671 RGD:1601560, RGD:11073666, RGD:1331525 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TGFB2 transforming growth factor beta 2 ISO RGD PMID:14575314 RGD:2302107 NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619
JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 ISO RGD PMID:10198196 RGD:1601617 NCBI chr 9:99,103,647...99,154,192
Ensembl chr 9:99,104,038...99,154,192
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO RGD PMID:10198196 RGD:1601617 NCBI chr 3:30,606,356...30,694,142
Ensembl chr 3:30,606,478...30,694,249
JBrowse link
G TH tyrosine hydroxylase no_association IAGP DNA:polymorphism:intron:g.1170_1173dupTCAT (human) RGD PMID:16139102 RGD:1580048 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815
JBrowse link
G THBD thrombomodulin EXP CTD Direct Evidence: marker/mechanism CTD PMID:9843165 PMID:10627464 NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672
JBrowse link
G THBS1 thrombospondin 1 ISO mRNA, protein:increased expression:myocardium RGD PMID:16179730 RGD:2317960 NCBI chr15:39,581,079...39,599,466
Ensembl chr15:39,581,079...39,599,466
JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24358288 NCBI chr17:78,852,977...78,925,387
Ensembl chr17:78,852,977...78,925,387
JBrowse link
G TLR4 toll like receptor 4 IAGP DNA:SNP:intron:rs1927911, minor allele associated with decreased risk RGD PMID:15864121 PMID:18549840 RGD:1580734, RGD:5562819 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
G TM6SF2 transmembrane 6 superfamily member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24633158 NCBI chr19:19,264,366...19,273,301
Ensembl chr19:19,264,364...19,273,391
JBrowse link
G TNC tenascin C ISO protein:increased expression:heart, fibroblast RGD PMID:11454990 RGD:4889618 NCBI chr 9:115,019,575...115,118,157
Ensembl chr 9:115,019,575...115,118,207
JBrowse link
G TNF tumor necrosis factor ISO
EXP
mRNA, protein:increased expression:left ventricle myocardium, plasma
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:15883752 PMID:16310260 PMID:21362018 RGD:5130892 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b IEP RGD PMID:15926884 RGD:1620893 NCBI chr 8:118,923,557...118,951,885
Ensembl chr 8:118,923,557...118,951,885
JBrowse link
G TNFRSF12A TNF receptor superfamily member 12A EXP CTD Direct Evidence: marker/mechanism CTD PMID:20082609 NCBI chr16:3,020,368...3,022,383
Ensembl chr16:3,018,445...3,022,383
JBrowse link
G TNFRSF14 TNF receptor superfamily member 14 ISO protein:increased expression:heart, cardiomyocyte, endothelial cell (rat) RGD PMID:18353719 RGD:2317281 NCBI chr 1:2,554,234...2,563,829
Ensembl chr 1:2,555,639...2,565,382
JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A ISO mRNA, protein:increased expression:left ventricle myocardium (rat) RGD PMID:15117889 PMID:20651834 PMID:21362018 RGD:1624194, RGD:5130975, RGD:5130892 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114
JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B ISO mRNA, protein:decreased expression:left ventricle myocardium (rat) RGD PMID:21362018 RGD:5130892 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228
JBrowse link
G TNFSF11 TNF superfamily member 11 IEP protein:increased expression:serum RGD PMID:18298349 RGD:2302363 NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013
JBrowse link
G TNFSF4 TNF superfamily member 4 susceptibility IAGP
EXP
CTD Direct Evidence: marker/mechanism CTD
OMIM
RGD
PMID:15750594 RGD:1580396 NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,162,645...173,477,583
JBrowse link
G TNNI3 troponin I3, cardiac type EXP CTD Direct Evidence: marker/mechanism CTD PMID:12359538 NCBI chr19:55,151,767...55,157,732
Ensembl chr19:55,151,767...55,157,773
JBrowse link
G TNNT2 troponin T2, cardiac type IEP RGD PMID:15226628 RGD:1580441 NCBI chr 1:201,359,014...201,377,680
Ensembl chr 1:201,359,008...201,377,764
JBrowse link
G TP53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24358288 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 ameliorates
disease_progression
ISO
IEP
RGD PMID:25840803 PMID:25840803 PMID:25840803 RGD:127284842, RGD:127284842, RGD:127284842 NCBI chr 6:41,267,385...41,286,682
Ensembl chr 6:41,267,926...41,286,682
JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 ISO RGD PMID:27671317 RGD:13792689 NCBI chr17:3,565,446...3,609,411
Ensembl chr17:3,565,444...3,609,411
JBrowse link
G TTN titin ISO RGD PMID:12221049 RGD:1580780 NCBI chr 2:178,525,989...178,807,423
Ensembl chr 2:178,525,989...178,830,802
JBrowse link
G TXN thioredoxin IEP RGD PMID:14677813 RGD:1580785 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507
JBrowse link
G TXNRD1 thioredoxin reductase 1 ISO mRNA:decreased expression:heart left ventricle (rat) RGD PMID:18515646 RGD:5134341 NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307
JBrowse link
G UBD ubiquitin D ISO mRNA, protein; increased expression; myocardium (rat) RGD PMID:29438664 RGD:126925221 NCBI chr 6:29,555,515...29,559,732
Ensembl chr 6:29,555,515...29,559,732
JBrowse link
G UTS2 urotensin 2 ISO associated with Heart Failure, Congestive;mRNA:increased expression:heart ventricle RGD PMID:15549273 RGD:2306846 NCBI chr 1:7,847,612...7,913,249
Ensembl chr 1:7,843,083...7,853,512
JBrowse link
G UTS2R urotensin 2 receptor ISO associated with Heart Failure, Congestive;mRNA:increased expression:heart ventricle RGD PMID:15549273 RGD:2306846 NCBI chr17:82,371,765...82,377,458
Ensembl chr17:82,371,765...82,377,458
JBrowse link
G VCAN versican ISO RGD PMID:16311904 RGD:1598497 NCBI chr 5:83,471,744...83,582,302
Ensembl chr 5:83,471,618...83,582,303
JBrowse link
G VDAC1 voltage dependent anion channel 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25488258 NCBI chr 5:133,971,871...134,114,540
Ensembl chr 5:133,971,871...134,004,975
JBrowse link
G VDAC2 voltage dependent anion channel 2 treatment ISO RGD PMID:20601275 RGD:10003049 NCBI chr10:75,210,170...75,231,448
Ensembl chr10:75,210,154...75,231,448
JBrowse link
G VEGFA vascular endothelial growth factor A treatment IEP
ISO
protein:increased expression:serum,platelet: RGD PMID:10652191 PMID:25936512 RGD:7483604, RGD:126925214 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
G VEGFB vascular endothelial growth factor B IMP RGD PMID:17975666 RGD:2314324 NCBI chr11:64,234,584...64,239,264
Ensembl chr11:64,234,584...64,239,264
JBrowse link
G VWF von Willebrand factor ISO protein:increased expression:heart: RGD PMID:19435557 RGD:11080745 NCBI chr12:5,948,877...6,124,670
Ensembl chr12:5,948,877...6,124,770
JBrowse link
G WDR12 WD repeat domain 12 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19198609 PMID:25915632 NCBI chr 2:202,874,261...202,911,673
Ensembl chr 2:202,874,261...203,014,798
JBrowse link
G WRN WRN RecQ like helicase IAGP RGD PMID:9021029 RGD:1580821 NCBI chr 8:31,033,810...31,176,138
Ensembl chr 8:31,033,788...31,176,138
JBrowse link
G XRCC3 X-ray repair cross complementing 3 susceptibility IAGP DNA:polymorphism:: (human) RGD PMID:18712175 RGD:401827276 NCBI chr14:103,697,617...103,715,451
Ensembl chr14:103,697,609...103,715,504
JBrowse link
G YBX1 Y-box binding protein 1 ISO RGD PMID:16002047 RGD:1580630 NCBI chr 1:42,682,418...42,703,805
Ensembl chr 1:42,682,418...42,703,805
JBrowse link
G ZEB2 zinc finger E-box binding homeobox 2 ISO protein:increased expression:heart (rat) RGD PMID:24155330 RGD:155882536 NCBI chr 2:144,384,081...144,520,119
Ensembl chr 2:144,364,364...144,521,057
JBrowse link
acute myocardial infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARHGAP17 Rho GTPase activating protein 17 ameliorates ISO RGD PMID:32068187 RGD:267358468 NCBI chr16:24,919,389...25,015,369
Ensembl chr16:24,919,389...25,015,666
JBrowse link
G BAX BCL2 associated X, apoptosis regulator ameliorates ISO RGD PMID:32068187 RGD:267358468 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G C3 complement C3 IEP RGD PMID:26476955 RGD:11552746 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G CACNG4 calcium voltage-gated channel auxiliary subunit gamma 4 IEP mRNA:decreased expression:blood: RGD PMID:27746059 RGD:13524557 NCBI chr17:66,964,707...67,033,398
Ensembl chr17:66,964,707...67,033,398
JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:26550220 RGD:13782284 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASP7 caspase 7 treatment ISO RGD PMID:26550220 RGD:13782284 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907
JBrowse link
G CCN1 cellular communication network factor 1 ameliorates ISO RGD PMID:30371213 RGD:329845516 NCBI chr 1:85,580,761...85,583,950
Ensembl chr 1:85,580,761...85,584,589
JBrowse link
G DSC2 desmocollin 2 ameliorates ISO RGD PMID:32068187 RGD:267358468 NCBI chr18:31,058,840...31,102,421
Ensembl chr18:31,058,545...31,102,600
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit treatment ISO RGD PMID:23054911 RGD:405650598 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase HEP mRNA:increased expression:blood RGD PMID:35693610 RGD:329901852 NCBI chr16:53,703,963...54,121,941
Ensembl chr16:53,701,692...54,158,512
JBrowse link
G GATA5 GATA binding protein 5 susceptibility IAGP DNA:SNPs:promoter:rs80197101, rs77067995 (human) RGD PMID:33684162 RGD:155260335 NCBI chr20:62,463,497...62,475,995
Ensembl chr20:62,463,497...62,475,995
JBrowse link
G GP6 glycoprotein VI platelet ameliorates
sexual_dimorphism
IAGP DNA:missense mutation:CDS:p.S219P (rs1613662) (human)
DNA:missense mutation:intron 1, intron 5: (rs1671207, rs11084382) (human)
RGD PMID:20227257 PMID:20227257 RGD:401794138, RGD:401794138 NCBI chr19:55,013,705...55,038,264
Ensembl chr19:55,013,705...55,038,264
JBrowse link
G GPX3 glutathione peroxidase 3 IEP protein:increased expression:plasma RGD PMID:28374671 RGD:401827832 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988
JBrowse link
G GSK3B glycogen synthase kinase 3 beta treatment
ameliorates
ISO RGD PMID:26591365 PMID:32068187 RGD:13792778, RGD:267358468 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994
JBrowse link
G H19 H19 imprinted maternally expressed transcript ameliorates ISO RGD PMID:31755219 RGD:213230161 NCBI chr11:1,995,176...2,001,466
Ensembl chr11:1,995,166...2,004,552
JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 IAGP ClinVar Annotator: match by term: Acute myocardial infarction ClinVar PMID:20946881 PMID:21250968 PMID:21596855 PMID:21997850 PMID:22160010 More... NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,477
JBrowse link
G IFNG interferon gamma ameliorates ISO RGD PMID:32068187 RGD:267358468 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma ameliorates ISO RGD PMID:32068187 RGD:267358468 NCBI chr  X:154,541,238...154,565,046
Ensembl chr  X:154,541,199...154,565,046
JBrowse link
G IL10 interleukin 10 ameliorates ISO RGD PMID:32068187 RGD:267358468 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL17A interleukin 17A ameliorates ISO RGD PMID:32068187 RGD:267358468 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638
JBrowse link
G IL1B interleukin 1 beta ameliorates ISO RGD PMID:32068187 RGD:267358468 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL1RL1 interleukin 1 receptor like 1 ISO RGD PMID:24837094 RGD:40813741 NCBI chr 2:102,311,563...102,352,356
Ensembl chr 2:102,311,502...102,352,037
JBrowse link
G IL33 interleukin 33 ISO RGD PMID:24837094 RGD:40813741 NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983
JBrowse link
G IL4 interleukin 4 ameliorates ISO RGD PMID:32068187 RGD:267358468 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G IL6 interleukin 6 ameliorates ISO RGD PMID:32068187 RGD:267358468 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G ITGAM integrin subunit alpha M treatment IEP RGD PMID:21238619 RGD:329901664 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892
JBrowse link
G KIF6 kinesin family member 6 IAGP DNA:SNP: :p.W719R (rs20455) (human) RGD PMID:20044086 RGD:243048455 NCBI chr 6:39,329,990...39,725,408
Ensembl chr 6:39,329,990...39,725,408
JBrowse link
G MALAT1 metastasis associated lung adenocarcinoma transcript 1 ameliorates ISO RGD PMID:29990866 RGD:155882565 NCBI chr11:65,497,738...65,506,516
Ensembl chr11:65,497,640...65,508,073
JBrowse link
G MIR126 microRNA 126 disease_progression IEP RGD PMID:36523365 PMID:32595526 RGD:401851047, RGD:401851053 NCBI chr 9:136,670,602...136,670,686
Ensembl chr 9:136,670,602...136,670,686
JBrowse link
G MIR146A microRNA 146a IEP miRNA:increased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr 5:160,485,352...160,485,450
Ensembl chr 5:160,485,352...160,485,450
JBrowse link
G MIR155 microRNA 155 IEP miRNA:decreased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044
JBrowse link
G MIR17 microRNA 17 treatment ISO RGD PMID:29536180 RGD:329403057 NCBI chr13:91,350,605...91,350,688
Ensembl chr13:91,350,605...91,350,688
JBrowse link
G MIR21 microRNA 21 IEP miRNA:increased expression:peripheral blood mononuclear cell, plasma
RNA:decreased expression:serum
RGD PMID:31866771 PMID:32595526 RGD:21081515, RGD:401851053 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337
JBrowse link
G MIR223 microRNA 223 treatment ISO RGD PMID:29689569 RGD:25823140 NCBI chr  X:66,018,870...66,018,979
Ensembl chr  X:66,018,870...66,018,979
JBrowse link
G MIR320A microRNA 320a ISO RGD PMID:29990866 RGD:155882565 NCBI chr 8:22,244,966...22,245,037
Ensembl chr 8:22,244,962...22,245,043
JBrowse link
G MT-CO2 mitochondrially encoded cytochrome c oxidase II ameliorates ISO RGD PMID:32068187 RGD:267358468 NCBI chr MT:7,586...8,269
Ensembl chr MT:7,586...8,269
JBrowse link
G NDUFB5 NADH:ubiquinone oxidoreductase subunit B5 ameliorates ISO associated with obesity RGD PMID:35257523 RGD:401794445 NCBI chr 3:179,604,794...179,627,647
Ensembl chr 3:179,604,690...179,627,647
JBrowse link
G PF4 platelet factor 4 treatment ISO RGD PMID:29407168 RGD:329901925 NCBI chr 4:73,980,811...73,982,124
Ensembl chr 4:73,980,811...73,982,027
JBrowse link
G PLCG1 phospholipase C gamma 1 ameliorates ISO RGD PMID:32068187 RGD:267358468 NCBI chr20:41,137,543...41,177,626
Ensembl chr20:41,136,960...41,196,801
JBrowse link
G PPBP pro-platelet basic protein treatment ISO RGD PMID:29407168 RGD:329901925 NCBI chr 4:73,986,439...73,988,190
Ensembl chr 4:73,986,439...73,988,190
JBrowse link
G PTEN phosphatase and tensin homolog ameliorates ISO
IEP
mRNA:decreased expression:heart left ventricle (rat)
RNA:increased expression:serum
RGD PMID:26973267 PMID:32595526 PMID:29990866 RGD:11526378, RGD:401851053, RGD:155882565 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930
JBrowse link
G RHOA ras homolog family member A ameliorates ISO RGD PMID:32068187 RGD:267358468 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998
JBrowse link
G RIT2 Ras like without CAAX 2 ameliorates ISO RGD PMID:32068187 RGD:267358468 NCBI chr18:42,743,227...43,115,685
Ensembl chr18:42,743,227...43,115,691
JBrowse link
G SDHB succinate dehydrogenase complex iron sulfur subunit B ameliorates ISO associated with obesity RGD PMID:35257523 RGD:401794445 NCBI chr 1:17,018,722...17,054,032
Ensembl chr 1:17,018,664...17,054,151
JBrowse link
G SERPING1 serpin family G member 1 IEP
ISO
mRNA:increased expression:heart RGD PMID:26476955 PMID:26476955 RGD:11552746, RGD:11552746 NCBI chr11:57,597,685...57,614,848
Ensembl chr11:57,597,387...57,619,171
JBrowse link
G TBX1 T-box transcription factor 1 treatment ISO RGD PMID:27422448 RGD:155882497 NCBI chr22:19,756,703...19,783,593
Ensembl chr22:19,756,703...19,783,593
JBrowse link
G TNF tumor necrosis factor ameliorates ISO RGD PMID:32068187 RGD:267358468 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G ZEB1 zinc finger E-box binding homeobox 1 ameliorates ISO RGD PMID:32068187 RGD:267358468 NCBI chr10:31,318,417...31,529,804
Ensembl chr10:31,318,495...31,529,814
JBrowse link
anterolateral myocardial infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EDN1 endothelin 1 IEP protein:increased expression:aortic root, coronary sinus, plasma (human) RGD PMID:12581682 RGD:8661757 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194
JBrowse link
G SERPINE1 serpin family E member 1 disease_progression ISO protein:decreased expression, decreased activity:heart: RGD PMID:12615902 PMID:12615902 RGD:13208541, RGD:13208541 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
JBrowse link
Cardiogenic Shock term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPO erythropoietin EXP CTD Direct Evidence: marker/mechanism CTD PMID:19337937 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700
JBrowse link
G PLAT plasminogen activator, tissue type EXP CTD Direct Evidence: therapeutic CTD PMID:1430592 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
JBrowse link
G SOD2 superoxide dismutase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21062213 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
Coronary Artery Disease, Autosomal Dominant 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MEF2A myocyte enhancer factor 2A IAGP
EXP
ClinVar Annotator: match by term: Coronary artery disease, autosomal dominant, 1
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Coronary artery disease/myocardial infarction
ClinVar
CTD
OMIM
PMID:14645853 PMID:15496429 PMID:15841183 PMID:25741868 NCBI chr15:99,565,417...99,716,488
Ensembl chr15:99,565,417...99,716,488
JBrowse link
Coronary Artery Disease, Autosomal Dominant 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase IAGP ClinVar Annotator: match by term: Coronary artery disease, autosomal dominant 2 ClinVar PMID:25741868 PMID:28492532 NCBI chr 2:27,217,369...27,243,943
Ensembl chr 2:27,217,369...27,243,943
JBrowse link
G LRP6 LDL receptor related protein 6 IAGP
EXP
ClinVar Annotator: match by term: Coronary artery disease, autosomal dominant 2
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:17332414 PMID:23703864 PMID:25741868 PMID:28492532 NCBI chr12:12,116,025...12,267,044
Ensembl chr12:12,116,025...12,267,044
JBrowse link
myocardial stunning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16317512 NCBI chr12:110,280,616...110,351,093
Ensembl chr12:110,280,756...110,351,093
JBrowse link
G NOS2 nitric oxide synthase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:11927517 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G PLN phospholamban EXP CTD Direct Evidence: marker/mechanism CTD PMID:16317512 NCBI chr 6:118,548,296...118,561,716
Ensembl chr 6:118,548,296...118,561,716
JBrowse link
G TNF tumor necrosis factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:11927517 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
No-Reflow Phenomenon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDH5 cadherin 5 EXP CTD Direct Evidence: therapeutic CTD PMID:16824628 NCBI chr16:66,366,691...66,404,784
Ensembl chr16:66,366,690...66,404,784
JBrowse link
G CTNNB1 catenin beta 1 EXP CTD Direct Evidence: therapeutic CTD PMID:16824628 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G JUP junction plakoglobin EXP CTD Direct Evidence: therapeutic CTD PMID:16824628 NCBI chr17:41,754,609...41,786,711
Ensembl chr17:41,754,604...41,786,931
JBrowse link
ST Elevation Myocardial Infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 treatment IAGP DNA:SNPs: :rs1045642,rs7779562(human) RGD PMID:25217066 RGD:14700903 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ATP5MC2 ATP synthase membrane subunit c locus 2 severity IEP RGD PMID:27441480 RGD:14696800 NCBI chr12:53,665,170...53,681,423
Ensembl chr12:53,632,726...53,677,408
JBrowse link
G CCN1 cellular communication network factor 1 sexual_dimorphism IEP protein:increased expression:blood serum (human) RGD PMID:34597881 RGD:329845519 NCBI chr 1:85,580,761...85,583,950
Ensembl chr 1:85,580,761...85,584,589
JBrowse link
G LGALS3 galectin 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29769800 NCBI chr14:55,129,252...55,145,430
Ensembl chr14:55,124,110...55,145,423
JBrowse link
G MIR208A microRNA 208a severity ISO miRNA:increased expression:blood RGD PMID:32458401 RGD:213230165 NCBI chr14:23,388,596...23,388,666
Ensembl chr14:23,388,596...23,388,666
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 35872
    disease of anatomical entity 32639
      cardiovascular system disease 6241
        vascular disease 3931
          Myocardial Ischemia 1006
            myocardial infarction 460
              Cardiogenic Shock 3
              Coronary Artery Disease, Autosomal Dominant 1 1
              Coronary Artery Disease, Autosomal Dominant 2 2
              No-Reflow Phenomenon 3
              Non-ST Elevated Myocardial Infarction 0
              ST Elevation Myocardial Infarction 5
              acute myocardial infarction + 48
              anterolateral myocardial infarction + 2
              apical myocardial infarction 0
              inferior myocardial infarction 0
              inferolateral myocardial infarct 0
              lateral myocardial infarction 0
              myocardial stunning 4
              posterior myocardial infarction 0
              posteroinferior myocardial infarction 0
              posterolateral myocardial infarction 0
              septal myocardial infarction 0
              silent myocardial infarction 0
              subendocardial myocardial infarction 0
Path 2
Term Annotations click to browse term
  disease 35872
    disease of anatomical entity 32639
      cardiovascular system disease 6241
        vascular disease 3931
          ischemia 1557
            Myocardial Ischemia 1006
              Coronary Disease 662
                coronary artery disease 630
                  myocardial infarction 460
                    Cardiogenic Shock 3
                    Coronary Artery Disease, Autosomal Dominant 1 1
                    Coronary Artery Disease, Autosomal Dominant 2 2
                    No-Reflow Phenomenon 3
                    Non-ST Elevated Myocardial Infarction 0
                    ST Elevation Myocardial Infarction 5
                    acute myocardial infarction + 48
                    anterolateral myocardial infarction + 2
                    apical myocardial infarction 0
                    inferior myocardial infarction 0
                    inferolateral myocardial infarct 0
                    lateral myocardial infarction 0
                    myocardial stunning 4
                    posterior myocardial infarction 0
                    posteroinferior myocardial infarction 0
                    posterolateral myocardial infarction 0
                    septal myocardial infarction 0
                    silent myocardial infarction 0
                    subendocardial myocardial infarction 0
paths to the root