Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:myocardial infarction
go back to main search page
Accession:DOID:5844 term browser browse the term
Definition:A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia. (DO)
Synonyms:exact_synonym: Cardiovascular Stroke;   Heart Attacks;   MCI2;   MYOCARDIAL INFARCTION, SUSCEPTIBILITY TO;   MYOCARDIAL INFARCTION, SUSCEPTIBILITY TO, 2;   Myocardial Infarct;   Myocardial Infarctions;   cardiovascular strokes;   heart attack;   myocardial infarcts
 narrow_synonym: MCI1;   MYOCARDIAL INFARCTION, PROTECTION AGAINST;   MYOCARDIAL INFARCTION, SUSCEPTIBILITY TO, 1;   post-operative myocardial infarction
 broad_synonym: F7-RELATED CONDITION
 related_synonym: MYOCARDIAL INFARCTION, DECREASED SUSCEPTIBILITY TO
 primary_id: MESH:D009203
 alt_id: MIM:608446;   MIM:608557
 xref: EFO:0000612;   EFO:0009953;   NCI:C27996
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:
myocardial infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc9 ATP binding cassette subfamily C member 9 ISO ClinVar Annotator: match by term: Myocardial infarction ClinVar PMID:16563363 PMID:18239147 PMID:20474083 PMID:21846889 PMID:23739550 More... NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356
JBrowse link
G Ace angiotensin I converting enzyme treatment
susceptibility
ISO
IEP
IMP
ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Type 1;DNA:deletion:intron:IVS16+1464-1751del (human)
associated with Myocardial Reperfusion Injury
ClinVar
CTD
RGD
PMID:1313972 PMID:1319114 PMID:1328889 PMID:1386652 PMID:1976655 More... RGD:1331525, RGD:9685449, RGD:1558664, RGD:7829785, RGD:6893480 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Ace2 angiotensin converting enzyme 2 treatment IEP
IDA
mRNA:increased expression:myocardium RGD PMID:15671045 PMID:23959549 RGD:1558664, RGD:9685449 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Acta2 actin alpha 2, smooth muscle ISO CTD Direct Evidence: marker/mechanism CTD PMID:24358288 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Acvr2a activin A receptor type 2A ISO mRNA:decreased expression:myocardium (mouse) RGD PMID:32427381 RGD:329849118 NCBI chr 3:33,204,961...33,292,673
Ensembl chr 3:33,205,523...33,289,968
JBrowse link
G Acvr2b activin A receptor type 2B ISO mRNA:decreased expression:myocardium (mouse) RGD PMID:32427381 RGD:329849118 NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:119,138,812...119,170,458
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 IEP RGD PMID:15625312 RGD:9681751 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
JBrowse link
G Add1 adducin 1 no_association ISO DNA:missense mutation:cds:p.G460W (human) RGD PMID:17082469 PMID:16420563 RGD:5147995, RGD:5148001 NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing disease_progression IEP RGD PMID:21326342 RGD:5686351 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Adipor1 adiponectin receptor 1 ISO mRNA, protein:decreased expression:heart left ventricle RGD PMID:16415076 RGD:1625764 NCBI chr13:45,859,461...45,879,248
Ensembl chr13:45,859,533...45,879,241
JBrowse link
G Adipor2 adiponectin receptor 2 ISO mRNA, protein:decreased expression:heart left ventricle RGD PMID:16415076 RGD:1625764 NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
JBrowse link
G Adora1 adenosine A1 receptor ISO CTD Direct Evidence: therapeutic CTD PMID:12160945 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
JBrowse link
G Adora3 adenosine A3 receptor ISO CTD Direct Evidence: therapeutic CTD PMID:12160945 PMID:20132822 NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357
JBrowse link
G Adra2b adrenoceptor alpha 2B ISO RGD PMID:12535806 RGD:1559314 NCBI chr 3:114,585,174...114,589,220
Ensembl chr 3:114,585,169...114,589,355
JBrowse link
G Adrb1 adrenoceptor beta 1 ISO
IMP
GAD
RGD
PMID:15118671 PMID:17143192 RGD:1331525, RGD:7241557 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Adrb2 adrenoceptor beta 2 susceptibility ISO
IEP
DNA:polymorphisms: :p.G16R, p.Q27E, p.T164I
mRNA:decreased expression:heart
RGD PMID:15520258 PMID:12400771 RGD:1601126, RGD:8548519 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Ager advanced glycosylation end product-specific receptor susceptibility IEP
ISO
mRNA:increased expression:left ventricle myocardium (rat)
DNA:polymorphism:promoter:-429T>C (human)
RGD PMID:19910580 PMID:16728681 RGD:2325647, RGD:1625333 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Agt angiotensinogen susceptibility IDA
ISO
associated with hypertension;DNA:polymorphism: :p.M235T
associated with Coronary Artery Disease;DNA:polymorphism: :p.M235T (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:1668233 PMID:16413583 PMID:21167013 PMID:17299437 PMID:11393670 More... RGD:5129191, RGD:1601132, RGD:1566452, RGD:1331525 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtr1a angiotensin II receptor, type 1a susceptibility
no_association
ISO
IEP
DNA:polymorphism:3' utr:1166A>C
DNA:polymorphism:3' utr:1166A>C (human)
RGD
GAD
PMID:16061119 PMID:9857918 PMID:15118671 PMID:9652322 RGD:1601150, RGD:1566499, RGD:1331525, RGD:10047101 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Ahsg alpha-2-HS-glycoprotein ISO protein:increased expression:plasma RGD PMID:19029462 RGD:2313810 NCBI chr11:78,121,388...78,127,998
Ensembl chr11:78,117,918...78,145,999
JBrowse link
G Aimp1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 IEP RGD PMID:14732363 RGD:1580021 NCBI chr 2:221,151,907...221,175,458
Ensembl chr 2:221,151,904...221,175,728
JBrowse link
G Ak1 adenylate kinase 1 treatment IEP RGD PMID:22229508 RGD:11100025 NCBI chr 3:15,912,431...15,923,045
Ensembl chr 3:15,912,485...15,923,041
JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO
IDA
protein:increased serine phosphorylation:platelet
protein:decreased serine phosphorylation:heart
RGD PMID:20467748 PMID:20352476 RGD:5509094, RGD:10041035 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO DNA:missense mutation: :p.E487K (human) RGD PMID:12452318 RGD:2311152 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein no_association ISO DNA:snps:multiple (human) RGD
GAD
PMID:14770184 PMID:19046748 PMID:15118671 RGD:1578317, RGD:2313891, RGD:1331525 NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986
JBrowse link
G Ang angiogenin ISO RGD PMID:18462761 RGD:2325719 NCBI chr15:24,312,711...24,323,361 JBrowse link
G Angpt1 angiopoietin 1 IEP mRNA, protein:decreased expression:myocardium RGD PMID:15364619 RGD:1626168 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067
JBrowse link
G Angpt2 angiopoietin 2 IEP protein:increased expression:left ventricular wall, heart septum (rat) RGD PMID:16714360 RGD:1601493 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804
JBrowse link
G Anxa5 annexin A5 susceptibility
no_association
ISO
IEP
DNA:polymorphism: :-1C>T (human)
protein:increased expression:plasma
protein:altered localization:cardiac muscle cell, sarcolemma
RGD PMID:12200370 PMID:16025836 PMID:8814351 PMID:16501019 RGD:2317542, RGD:1578384, RGD:2317543, RGD:2317541 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 susceptibility ISO DNA:polymorphism:exon 5: G>A (human) RGD PMID:18712175 RGD:401827276 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
JBrowse link
G Apoa1 apolipoprotein A1 no_association ISO DNA:polymorphisms RGD
GAD
PMID:20176799 PMID:10428310 PMID:15118671 RGD:2325759, RGD:1578442, RGD:1331525 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoa4 apolipoprotein A4 no_association
susceptibility
ISO DNA:mutation:intron:IVS2 (human)
associated with Diabetes Mellitus, Type 2; DNA:missense mutation:cds:p.Q360H (human)
RGD
GAD
PMID:10428310 PMID:15118671 PMID:7958503 RGD:1578442, RGD:1331525, RGD:5685678 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apob apolipoprotein B ISO GAD PMID:15118671 RGD:1331525 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G Apoc3 apolipoprotein C3 no_association ISO ClinVar Annotator: match by term: Myocardial infarction, susceptibility to ClinVar
RGD
PMID:10428310 PMID:15118671 RGD:1578442, RGD:1331525 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Apoe apolipoprotein E susceptibility ISO DNA:missense mutations, haplotypes:cds:p.C112R, p.R158C (human)
DNA:missense mutations, haplotype:cds:p.C112R, p.C158R (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:10587578 PMID:17217375 PMID:15118671 PMID:10090925 RGD:1601229, RGD:1331525, RGD:10449412 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Apoh apolipoprotein H ISO
IDA
RGD PMID:15322656 PMID:12826288 RGD:2313985, RGD:10054111 NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329
JBrowse link
G Atg7 autophagy related 7 IEP mRNA:increased expression:plantaris RGD PMID:24427319 RGD:11557988 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Atm ATM serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:24358288 PMID:24358288 RGD:10053570 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 ISO CTD Direct Evidence: therapeutic CTD PMID:29702141 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Atp5f1d ATP synthase F1 subunit delta treatment IEP protein:decreased expression:myocardium (rat) RGD PMID:29300489 PMID:23809007 RGD:13792656, RGD:13792681 NCBI chr 7:9,560,604...9,565,919
Ensembl chr 7:9,560,608...9,565,929
JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP treatment ISO RGD PMID:24692845 RGD:13801194 NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592
JBrowse link
G Avpr1a arginine vasopressin receptor 1A IMP RGD PMID:16423716 RGD:2300376 NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215
JBrowse link
G Bak1 BCL2-antagonist/killer 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29122578 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:20079142 PMID:25450231 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:19027736 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 IMP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:20079142 PMID:17467744 RGD:1643494 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bdkrb1 bradykinin receptor B1 IEP mRNA:increased expression:heart RGD PMID:12489796 RGD:704379 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
JBrowse link
G Bdkrb2 bradykinin receptor B2 IEP mRNA:increased expression:heart RGD PMID:12489796 RGD:704379 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497
JBrowse link
G Becn1 beclin 1 treatment ISO
IEP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:20079142 PMID:20079142 RGD:11561913 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 IEP RGD PMID:15081314 RGD:2293137 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bnip3 BCL2 interacting protein 3 IEP mRNA:increased expression:plantaris RGD PMID:24427319 RGD:11557988 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Brap BRCA1 associated protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198608 NCBI chr12:34,874,533...34,901,030
Ensembl chr12:34,874,533...34,901,030
JBrowse link
G Brinp3 BMP/retinoic acid inducible neural specific 3 susceptibility ISO DNA:SNPs:3' end: RGD PMID:18430236 RGD:14398488 NCBI chr13:58,413,883...58,846,828
Ensembl chr13:58,413,883...58,846,770
JBrowse link
G C3 complement C3 IEP mRNA, protein:increased expression:myocardium RGD PMID:16996480 RGD:1600605 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G C7 complement C7 IEP Protein:increased activity:serum, myocardium RGD PMID:15724448 RGD:1599522 NCBI chr 2:54,088,116...54,165,102
Ensembl chr 2:54,088,116...54,158,535
JBrowse link
G C8a complement C8 alpha chain IEP RGD PMID:7515561 RGD:1600501 NCBI chr 5:119,583,168...119,637,675
Ensembl chr 5:119,583,174...119,637,754
JBrowse link
G C8b complement C8 beta chain IEP RGD PMID:7515561 RGD:1600501 NCBI chr 5:119,535,009...119,572,565
Ensembl chr 5:119,535,146...119,572,565
JBrowse link
G Cacybp calcyclin binding protein IEP mRNA:increased expression:heart RGD PMID:16440310 RGD:2326117 NCBI chr13:72,437,485...72,447,810
Ensembl chr13:72,437,490...72,450,177
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta treatment IEP mRNA, protein:splice variants, increased expression:heart left ventricle (rat) RGD PMID:26067684 RGD:11097969 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178
JBrowse link
G Casp1 caspase 1 severity
ameliorates
ISO
IEP
RGD PMID:17303764 PMID:33389498 RGD:2315913, RGD:242905187 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 ameliorates
treatment
ISO
IEP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:25450231 PMID:28622474 PMID:27904666 RGD:329333030, RGD:13782309 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casr calcium-sensing receptor IEP protein:increased expression:myocardium (rat) RGD PMID:22527939 RGD:7205672 NCBI chr11:64,235,251...64,304,811
Ensembl chr11:64,235,251...64,304,811
JBrowse link
G Cat catalase IEP
ISO
CTD Direct Evidence: therapeutic CTD
RGD
PMID:21600015 PMID:14575298 RGD:1581148 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cav3 caveolin 3 IEP Protein:increased expression:cytosol
mRNA, protein; increased expression; myocardium (rat)
RGD PMID:12566108 PMID:29438664 RGD:1599542, RGD:126925221 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment IEP
IDA
ISO
protein:increased expression:serum
DNA:snp:promoter:g.-2518A>G (human)
RGD PMID:18459941 PMID:18753699 PMID:16116069 RGD:2307033, RGD:8549616, RGD:1581161 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IEP mRNA:increased expression:heart (rat) RGD PMID:18954648 RGD:4890013 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccn1 cellular communication network factor 1 ISO mRNA,protein:increased expression:myocardium (mouse) RGD PMID:15117851 RGD:329845570 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Ccn2 cellular communication network factor 2 treatment IEP mRNA:increased expression:left ventricle (rat) RGD PMID:18167060 PMID:29849775 RGD:2314623, RGD:35673318 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccna2 cyclin A2 IEP protein:increased expression:cardiomyocyte: RGD PMID:23634243 RGD:10054471 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO RGD PMID:12719858 PMID:12853162 RGD:1581177, RGD:1581174 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Ccr3 C-C motif chemokine receptor 3 IDA RGD PMID:18954648 RGD:4890013 NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990
JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 ISO ClinVar Annotator: match by term: Myocardial infarction, susceptibility to, 1 ClinVar PMID:24213632 NCBI chr 4:117,989,232...118,006,478
Ensembl chr 4:117,989,232...118,006,580
JBrowse link
G Cd14 CD14 molecule no_association ISO associated with Coronary Artery Disease;DNA:SNP:promoter RGD PMID:10195920 PMID:14587643 PMID:17436151 RGD:1580252, RGD:1580255, RGD:2314155 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd36 CD36 molecule severity IMP RGD PMID:22128087 RGD:6893560 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cd40lg CD40 ligand ISO protein:increased expression:serum RGD PMID:17635572 RGD:2314209 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Cd59b CD59b molecule IEP protein:decreased expression:myocardium RGD PMID:7515561 RGD:1600501 NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B treatment IMP
ISO
RGD PMID:22492676 PMID:22492676 RGD:10045366, RGD:10045366 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cfl1 cofilin 1 treatment IDA RGD PMID:24292258 RGD:11570534 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
JBrowse link
G Cftr CF transmembrane conductance regulator ISO associated with Myocardial Reperfusion Injury RGD PMID:23221371 RGD:11566046 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Chi3l1 chitinase 3 like 1 ISO protein:increased secretion:serum (human) RGD PMID:18480670 RGD:4892633 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787
JBrowse link
G Ciita class II, major histocompatibility complex, transactivator susceptibility
no_association
ISO DNA:polymorphism:promoter:-168A>G (human) RGD PMID:15821736 PMID:17183695 RGD:1358146, RGD:5491201 NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440
JBrowse link
G Ckb creatine kinase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:12359538 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
JBrowse link
G Ckm creatine kinase, M-type ISO CTD Direct Evidence: marker/mechanism CTD PMID:3279722 PMID:12359538 NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720
JBrowse link
G Clu clusterin treatment ISO RGD PMID:20854280 RGD:9068409 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Col1a1 collagen type I alpha 1 chain treatment IEP RGD PMID:25636075 RGD:11041598 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col3a1 collagen type III alpha 1 chain treatment IEP RGD PMID:25636075 RGD:11041598 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Col4a1 collagen type IV alpha 1 chain susceptibility ISO DNA:polymorphism: :p.Q1334H (human) RGD PMID:18077766 RGD:2311341 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
JBrowse link
G Col6a3 collagen type VI alpha 3 chain ISO DNA:SNP:CDS:E1386K (rs146092501) (human) RGD PMID:30226566 RGD:401851058 NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:91,361,583...91,439,471
JBrowse link
G Creb1 cAMP responsive element binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19027736 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crem cAMP responsive element modulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:19027736 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
JBrowse link
G Crp C-reactive protein IEP
ISO
protein:increased expression:serum
associated with Angina, Unstable;
RGD PMID:21046814 PMID:9761079 PMID:22446866 RGD:5131456, RGD:9491780, RGD:6482304 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cs citrate synthase severity IDA
ISO
protein:decreased expression:diaphragm, mitochondrion RGD PMID:1877670 PMID:34416105 RGD:243048469, RGD:243048471 NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
JBrowse link
G Csf2 colony stimulating factor 2 IMP RGD PMID:21326109 RGD:5131507 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Csf3 colony stimulating factor 3 treatment ISO RGD PMID:15639484 RGD:11039417 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 IEP RGD PMID:15090263 RGD:11565830 NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696
JBrowse link
G Csnk2b casein kinase 2 beta IEP RGD PMID:15090263 RGD:11565830 NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 ISO DNA:SNP:CDS:49A>G (human) RGD PMID:17652883 RGD:2301976 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963
JBrowse link
G Ctsb cathepsin B IEP protein:increased activity:serum, heart (rat) RGD PMID:19958779 RGD:2315501 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 IEP
IMP
mRNA:increased expression:heart left ventricle RGD PMID:11820456 PMID:19187644 RGD:632503, RGD:2306567 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cyba cytochrome b-245 alpha chain IEP mRNA:increased expression:myocardium
mRNA:increase expression:ventricle myocardium:
RGD PMID:18762777 PMID:11243862 RGD:2317860, RGD:1599690 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cybb cytochrome b-245 beta chain IEP mRNA:increase expression:ventricle myocardium RGD PMID:11243862 RGD:1599690 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 IMP RGD PMID:18689429 RGD:2307303 NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 ameliorates IMP RGD PMID:33389498 RGD:242905187 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 susceptibility ISO DNA:polymorphism RGD PMID:17126841 RGD:1625380 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
JBrowse link
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 ISO DNA:SNP:CDS:rs2060793, rs1993116, rs10766197 (human) RGD PMID:29804528 RGD:401901167 NCBI chr 1:168,749,302...168,798,079
Ensembl chr 1:168,751,038...168,797,759
JBrowse link
G Dab2 DAB adaptor protein 2 IEP
IMP
protein:increased expression:cardiomyocyte RGD PMID:21762377 PMID:20666606 RGD:7243156, RGD:7243158 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
JBrowse link
G Dab2ip DAB2 interacting protein onset ISO CTD Direct Evidence: marker/mechanism
DNA:SNP:CDS:intron 1 (rs7025486) (human)
CTD
RGD
PMID:20622881 PMID:20622881 RGD:401901599 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280
JBrowse link
G Dag1 dystroglycan 1 treatment IDA RGD PMID:12034665 RGD:11541047 NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325
JBrowse link
G Dcn decorin IEP RGD PMID:16311904 RGD:1598497 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25450231 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Dgkz diacylglycerol kinase zeta ISO CTD Direct Evidence: therapeutic CTD PMID:17071729 NCBI chr 3:77,904,149...77,946,114
Ensembl chr 3:77,904,150...77,946,099
JBrowse link
G Dvl1 dishevelled segment polarity protein 1 IEP RGD PMID:15256074 RGD:1580899 NCBI chr 5:166,456,989...166,468,733
Ensembl chr 5:166,456,686...166,468,664
JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A treatment IEP associated with heart failure; protein:increased expression, increased activity:heart left ventricle (rat) RGD PMID:26067684 RGD:11097969 NCBI chr11:33,890,706...34,009,420
Ensembl chr11:33,890,490...34,009,420
JBrowse link
G Ece1 endothelin converting enzyme 1 ISO RGD PMID:9607404 RGD:1580912 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371
JBrowse link
G Edn1 endothelin 1 severity ISO
IEP
protein:increased secretion:plasma (human)
mRNA:increased expression:heart left ventricle (rat)
RGD PMID:17893002 PMID:10573185 RGD:4144880, RGD:1580921 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Edn2 endothelin 2 IEP RGD PMID:10573185 RGD:1580921 NCBI chr 5:133,751,316...133,756,814
Ensembl chr 5:133,751,217...133,756,814
JBrowse link
G Ednra endothelin receptor type A IDA RGD PMID:12524016 RGD:1580948 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Ednrb endothelin receptor type B IDA RGD PMID:12524016 RGD:1580948 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 IEP RGD PMID:16765982 RGD:11252084 NCBI chr19:52,867,900...52,907,308
Ensembl chr19:52,869,486...52,907,777
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 IEP RGD PMID:16765982 RGD:11252084 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
JBrowse link
G Epas1 endothelial PAS domain protein 1 IEP RGD PMID:15247145 PMID:18484163 RGD:1580977, RGD:5147886 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Ephb1 Eph receptor B1 ameliorates IEP RGD PMID:28622474 RGD:329333030 NCBI chr 8:102,507,549...102,944,839
Ensembl chr 8:102,507,549...102,944,839
JBrowse link
G Ephx2 epoxide hydrolase 2 ISO RGD PMID:19716829 RGD:5688358 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Epo erythropoietin treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19337937 PMID:21415704 RGD:10400907 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G Epor erythropoietin receptor IEP RGD PMID:21415704 RGD:10400907 NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 treatment IEP RGD PMID:26892146 RGD:11522702 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 treatment IEP RGD PMID:26892146 RGD:11522702 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
JBrowse link
G Esr1 estrogen receptor 1 susceptibility ISO ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:11894143 PMID:11919305 PMID:14600184 PMID:15133719 PMID:25741868 More... RGD:1331525 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G F10 coagulation factor X ISO ClinVar Annotator: match by term: Myocardial infarction, decreased susceptibility to ClinVar PMID:10984565 PMID:12181036 PMID:25741868 NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141
JBrowse link
G F12 coagulation factor XII susceptibility ISO DNA:polymorphism:promoter:-46C>T(human) RGD PMID:16411408 RGD:11041803 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530
JBrowse link
G F13a1 coagulation factor XIII A1 chain ISO ClinVar Annotator: match by term: Myocardial infarction, protection against
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
RGD
PMID:8025280 PMID:9459313 PMID:9550516 PMID:10365735 PMID:10910914 More... RGD:1581022 NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700
JBrowse link
G F2 coagulation factor II, thrombin susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphism::20210G>A(human)
CTD
RGD
PMID:9292507 PMID:9531249 PMID:10027711 PMID:12480694 RGD:1581022 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F3 coagulation factor III, tissue factor treatment IEP RGD PMID:21229253 RGD:11062083 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G F5 coagulation factor V no_association
susceptibility
ISO CTD Direct Evidence: marker/mechanism
DNA:mutation:cds:1691G>A (human)
CTD
RGD
PMID:9531249 PMID:10590188 PMID:15131548 RGD:11564337, RGD:11564335 NCBI chr13:76,513,509...76,583,106
Ensembl chr13:76,513,255...76,582,317
JBrowse link
G F7 coagulation factor VII susceptibility ISO protein:increased activity:plasma (human)
ClinVar Annotator: match by term: F7-related condition | ClinVar Annotator: match by term: Myocardial infarction, decreased susceptibility to | ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
CTD Direct Evidence: marker/mechanism
DNA:missense mutation, repeat:cds, intron:p.R353Q, (human)
OMIM
ClinVar
CTD
RGD
PMID:1634227 PMID:2070047 PMID:6812354 PMID:7919338 PMID:7981691 More... RGD:2312409, RGD:11049521, RGD:1580374 NCBI chr16:76,489,775...76,500,636
Ensembl chr16:76,489,717...76,500,610
JBrowse link
G Fabp3 fatty acid binding protein 3 ISO RGD PMID:8326460 RGD:1582401 NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718
JBrowse link
G Fgb fibrinogen beta chain ISO GAD
RGD
PMID:15118671 PMID:9437197 RGD:1331525, RGD:1580381 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
JBrowse link
G Fgf1 fibroblast growth factor 1 treatment ISO RGD PMID:24200746 RGD:10449026 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 ISO RGD PMID:17439742 RGD:10402087 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ameliorates ISO RGD PMID:19358330 RGD:155663664 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Fis1 fission, mitochondrial 1 IEP protein:increased expression:plantaris (rat) RGD PMID:24427319 RGD:11557988 NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 IEP RGD PMID:16714360 RGD:1601493 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Flt3lg Fms related receptor tyrosine kinase 3 ligand treatment ISO RGD PMID:24184252 RGD:11049498 NCBI chr 1:95,615,056...95,620,463
Ensembl chr 1:95,609,370...95,620,463
JBrowse link
G Fn1 fibronectin 1 IEP protein:decreased expression:heart RGD PMID:19695229 RGD:2325720 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit IEP protein:increased expression:paraventricular nucleus hypothalamus, paraventricular nucleus thalamus RGD PMID:27601012 RGD:405649741 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fto FTO, alpha-ketoglutarate dependent dioxygenase treatment ISO mRNA, protein:decreased expression:heart
DNA:SNP: :rs17817449 (human)
associated with type 2 diabetes mellitus;DNA:SNP:intron:rs9939609 (human)
RGD PMID:29997116 PMID:26772723 PMID:20031593 PMID:29997116 RGD:329812009, RGD:11555187, RGD:329901766, RGD:329812009 NCBI chr19:15,284,898...15,692,142
Ensembl chr19:15,349,696...15,692,083
JBrowse link
G Fzd2 frizzled class receptor 2 IEP mRNA:increased expression:heart left ventricle RGD PMID:9142123 RGD:4107058 NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase treatment IEP RGD PMID:20462747 RGD:10449173 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gata4 GATA binding protein 4 treatment IMP
ISO
CTD Direct Evidence: therapeutic CTD
RGD
PMID:20200331 PMID:23948075 RGD:7327215 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636
JBrowse link
G Gatm glycine amidinotransferase ISO RGD PMID:31972362 RGD:329961305 NCBI chr 3:109,658,919...109,675,508
Ensembl chr 3:109,658,951...109,684,129
JBrowse link
G Gch1 GTP cyclohydrolase 1 treatment IDA
IEP
RGD PMID:32782412 PMID:26192027 RGD:329961570, RGD:329970290 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit ISO DNA:snp:promoter:c.-129C>T (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
OMIM
CTD
ClinVar
RGD
PMID:12598062 PMID:12598062 RGD:1302515 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit susceptibility ISO ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
OMIM
CTD
PMID:12081989 PMID:12975258 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19419996 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Gh1 growth hormone 1 treatment ISO RGD PMID:12500159 RGD:11352745 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
JBrowse link
G Ghrh growth hormone releasing hormone treatment IDA RGD PMID:24373935 RGD:10401242 NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889
JBrowse link
G Gja1 gap junction protein, alpha 1 treatment IEP
IMP
protein:decreased phosphorylation RGD PMID:22969867 PMID:29428663 PMID:22841862 RGD:7207261, RGD:13592597, RGD:7207262 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gja4 gap junction protein, alpha 4 ISO RGD PMID:15982495 RGD:1580400 NCBI chr 5:139,633,324...139,635,857
Ensembl chr 5:139,633,287...139,635,925
JBrowse link
G Gja5 gap junction protein, alpha 5 treatment IEP RGD PMID:29428663 RGD:13592597 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952
JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha ISO RGD PMID:15269835 RGD:1580432 NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774
JBrowse link
G Gp6 glycoprotein VI sexual_dimorphism
treatment
no_association
susceptibility
onset
ISO DNA:missense mutation:CDS:c.13254T>C (p.S219P) (human)
human protein in a mouse model
DNA:missense mutation:CDS:c.13254T>C (p.S219P) (rs1613662) (human)
DNA:missense mutation:exon 7:c.645213C>T (p.T249A) (human)
DNA:SNP, missense mutation:promoter, CDS:c.-148C>T, c.13254T>C (p.S219P) (human)
RGD PMID:11571236 PMID:22814400 PMID:20723028 PMID:12417295 PMID:11571236 More... RGD:401793749, RGD:401824647, RGD:401794407, RGD:401793754, RGD:401793749, RGD:401793749 NCBI chr 1:69,429,232...69,492,709
Ensembl chr 1:69,465,789...69,491,326
JBrowse link
G Gpt glutamic--pyruvic transaminase treatment IEP RGD PMID:32026788 RGD:401793703 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx1 glutathione peroxidase 1 susceptibility ISO RGD PMID:14573732 RGD:1600662 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment IMP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:16716347 PMID:16565311 RGD:10045368 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsn gelsolin ameliorates ISO
IEP
protein:decreased expression:blood serum (human) RGD PMID:9142022 PMID:28622474 RGD:329333022, RGD:329333030 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Gsr glutathione-disulfide reductase treatment IEP RGD PMID:25119867 RGD:10401898 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 ISO ClinVar Annotator: match by term: Myocardial infarction, susceptibility to, 1 ClinVar PMID:24213632 NCBI chr 2:167,418,615...167,482,293
Ensembl chr 2:167,418,640...167,481,671
JBrowse link
G H19 H19 imprinted maternally expressed transcript ameliorates IMP RGD PMID:33389498 RGD:242905187 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134
JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase IEP RGD PMID:11481570 RGD:2302229 NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353
JBrowse link
G Hamp hepcidin antimicrobial peptide IEP mRNA:increased expression:heart RGD PMID:19615879 RGD:11041636 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Hfe homeostatic iron regulator no_association
susceptibility
ISO RGD PMID:12850485 PMID:10491370 RGD:1582672, RGD:1582697 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502
JBrowse link
G Hgf hepatocyte growth factor treatment ISO protein:increased expression:serum: RGD PMID:12419930 PMID:16570015 RGD:8548609, RGD:8548632 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ameliorates
treatment
IEP
ISO
mRNA:increased expression:heart left ventricle
human gene in a rat model
RGD PMID:18484163 PMID:28622474 PMID:15247145 PMID:15999059 RGD:5147886, RGD:329333030, RGD:1580977, RGD:9068466 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmgb1 high mobility group box 1 treatment IDA
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:21113057 PMID:23188125 RGD:10402174 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565
JBrowse link
G Hmox1 heme oxygenase 1 IEP
IDA
RGD PMID:12392996 PMID:20925964 RGD:1598393, RGD:4145134 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hp haptoglobin susceptibility ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:16597321 PMID:17068284 PMID:17207726 PMID:3990081 PMID:2613263 RGD:1626360, RGD:1626354 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 ameliorates ISO RGD PMID:28522730 PMID:26465199 RGD:329902054, RGD:11087531 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 IEP
ISO
mRNA:increased expression:heart
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:17587755 PMID:17587755 RGD:2308939 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25450231 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 IEP RGD PMID:17202668 RGD:1624230 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment IEP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:10070497 PMID:23139358 RGD:8547733 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Igf1 insulin-like growth factor 1 severity IEP
ISO
mRNA, protein:increased expression:myocardium RGD PMID:19295919 PMID:16635594 RGD:2306696, RGD:1598421 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf1r insulin-like growth factor 1 receptor IEP mRNA,protein:increased expression:myocyte: RGD PMID:8682060 RGD:10046050 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Il10 interleukin 10 susceptibility ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:15883752 PMID:16310260 PMID:15466015 RGD:1598480 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il17a interleukin 17A IEP mRNA, protein:increased expression:heart left ventricle (rat) RGD PMID:23096364 RGD:9095344 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il18 interleukin 18 ameliorates IEP RGD PMID:33389498 RGD:242905187 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il18bp interleukin 18 binding protein ISO RGD PMID:19805173 RGD:4889400 NCBI chr 1:156,372,923...156,374,963
Ensembl chr 1:156,372,883...156,374,963
JBrowse link
G Il1b interleukin 1 beta ameliorates IDA
IEP
ISO
CTD Direct Evidence: marker/mechanism
protein:increased expression:serum (rat)
CTD
RGD
PMID:11743230 PMID:15883752 PMID:16310260 PMID:23143013 PMID:33389498 More... RGD:7175553, RGD:242905187, RGD:7204425 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO CTD Direct Evidence: therapeutic CTD PMID:18474815 PMID:19005744 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il4r interleukin 4 receptor IEP mRNA:increased expression:heart RGD PMID:10807530 RGD:4889985 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15883752 PMID:16310260 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il6r interleukin 6 receptor IEP RGD PMID:12123772 RGD:1625444 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Inhba inhibin subunit beta A IEP
ISO
mRNA:increased expression:heart (rat)
mRNA:increased expression:myocardium (mouse)
RGD PMID:14993131 PMID:32427381 RGD:1580888, RGD:329849118 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Inhbb inhibin subunit beta B ISO mRNA:increased expression:myocardium (mouse) RGD PMID:32427381 RGD:329849118 NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832
JBrowse link
G Isl1 ISL LIM homeobox 1 ameliorates ISO RGD PMID:29482621 PMID:22727192 RGD:243048463, RGD:243048464 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584
JBrowse link
G Itga2 integrin subunit alpha 2 susceptibility
no_association
ISO RGD PMID:16697311 PMID:10194421 PMID:15227729 RGD:1582296, RGD:1581029, RGD:1582294 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481
JBrowse link
G Itga3 integrin subunit alpha 3 IEP protein:increased expression:myocardium (rat) RGD PMID:19041328 RGD:2325287 NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118
JBrowse link
G Itgam integrin subunit alpha M treatment ISO RGD PMID:29933226 RGD:329853753 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Itgb1 integrin subunit beta 1 treatment IMP RGD PMID:28367125 RGD:13602094 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Itgb3 integrin subunit beta 3 no_association
susceptibility
ISO DNA:polymorphism:exon:
ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
CTD Direct Evidence: marker/mechanism
associated with arteriosclerosis; DNA:polymorphism:exon
OMIM
ClinVar
CTD
RGD
PMID:2014236 PMID:7570918 PMID:8598867 PMID:8667943 PMID:8838346 More... RGD:5128498, RGD:5128481, RGD:5128476 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 ISO RGD PMID:10486281 RGD:1582334 NCBI chr16:6,080,539...6,095,710
Ensembl chr16:6,080,539...6,095,708
JBrowse link
G Jak2 Janus kinase 2 susceptibility IMP associated with Myocardial Reperfusion Injury RGD PMID:22749532 RGD:10403083 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 treatment IDA RGD PMID:23647964 RGD:7247426 NCBI chr10:96,060,834...96,071,397
Ensembl chr10:96,060,821...96,071,445
JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 IEP mRNA:decreased expression:heart left ventricle, epicardium, endocardium (rat) RGD PMID:21683547 RGD:9831182 NCBI chr13:100,766,101...100,963,435
Ensembl chr13:100,766,113...100,963,435
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 susceptibility ISO DNA:SNPs,haplotypes:introns:multiple RGD PMID:19644414 RGD:329969896 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340
JBrowse link
G Kdm5b lysine demethylase 5B ameliorates ISO RGD PMID:36481938 RGD:329901769 NCBI chr13:46,001,589...46,073,868
Ensembl chr13:46,002,542...46,073,872
JBrowse link
G Kdm6a lysine demethylase 6A IEP mRNA:increased expression:myocardium (rat) RGD PMID:30887465 RGD:151665136 NCBI chr  X:4,337,466...4,477,100
Ensembl chr  X:4,337,750...4,477,062
JBrowse link
G Kdr kinase insert domain receptor treatment ISO
IDA
RGD PMID:16698275 PMID:25936512 RGD:1581717, RGD:126925214 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Kif6 kinesin family member 6 no_association
treatment
ISO CTD Direct Evidence: marker/mechanism
DNA:SNP: :p.W719R (rs20455) (human)
DNA:SNP: :rs20455 (human)
CTD
RGD
PMID:21943003 PMID:20927332 PMID:26997531 PMID:19371834 PMID:20403483 More... RGD:243048450, RGD:243048449, RGD:243048447, RGD:11097528, RGD:243048446 NCBI chr 9:11,076,203...11,373,205
Ensembl chr 9:11,072,824...11,373,006
JBrowse link
G Klf13 KLF transcription factor 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29122578 NCBI chr 1:117,505,857...117,536,626
Ensembl chr 1:117,503,602...117,551,227
JBrowse link
G Klk1 kallikrein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:12411458 NCBI chr 1:94,642,644...94,646,760
Ensembl chr 1:94,642,687...94,646,754
JBrowse link
G Klk1c12 kallikrein 1-related peptidase C12 ISO RGD PMID:17022964 RGD:1641799 NCBI chr 1:94,378,103...94,382,140
Ensembl chr 1:94,378,054...94,382,176
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 IEP mRNA:increased expression:plantaris RGD PMID:24427319 RGD:11557988 NCBI chr  X:117,173,097...117,222,090
Ensembl chr  X:117,057,606...117,260,522
JBrowse link
G Lcat lecithin cholesterol acyltransferase IDA RGD PMID:16640830 RGD:1581773 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Lcn2 lipocalin 2 ameliorates ISO RGD PMID:27800610 RGD:126790572 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Ldha lactate dehydrogenase A ISO CTD Direct Evidence: marker/mechanism CTD PMID:3279722 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
JBrowse link
G Ldlr low density lipoprotein receptor ISO GAD PMID:15118671 RGD:1331525 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lefty1 left right determination factor 1 ameliorates ISO RGD PMID:33409963 RGD:401794430 NCBI chr13:92,649,226...92,659,722
Ensembl chr13:92,656,323...92,659,720
JBrowse link
G Lgals2 galectin 2 susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
OMIM
CTD
ClinVar
RGD
PMID:15129282 PMID:15129282 RGD:1581852 NCBI chr 7:110,403,171...110,410,046
Ensembl chr 7:110,403,173...110,404,802
JBrowse link
G Lgals3 galectin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29769800 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
JBrowse link
G Lipg lipase G, endothelial type susceptibility ISO DNA:polymorphism: :584C>T RGD PMID:17526978 RGD:1641818 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
JBrowse link
G Lox lysyl oxidase ISO RGD PMID:14553832 RGD:1581883 NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
JBrowse link
G Lpl lipoprotein lipase susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:SNP: :p.D9N (rs1801177) (human) RGD PMID:18823627 RGD:2313302 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Lrp1 LDL receptor related protein 1 susceptibility ISO RGD PMID:12402342 RGD:1581913 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
JBrowse link
G Lrp8 LDL receptor related protein 8 no_association
susceptibility
onset
ISO DNA:missense mutation:cds:p.R952Q (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Myocardial infarction, susceptibility to, 1
CTD
OMIM
ClinVar
RGD
PMID:17847002 PMID:18592168 PMID:17847002 RGD:2306125, RGD:2306124 NCBI chr 5:122,563,468...122,635,434
Ensembl chr 5:122,563,453...122,631,352
JBrowse link
G Lrpap1 LDL receptor related protein associated protein 1 susceptibility ISO RGD PMID:12394648 RGD:1581922 NCBI chr14:75,651,371...75,663,380
Ensembl chr14:75,651,376...75,665,414
JBrowse link
G Lta lymphotoxin alpha no_association
susceptibility
severity
ISO ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
CTD Direct Evidence: marker/mechanism
DNA:SNP:exon:804C>A (p.T26N) (human)
ClinVar
OMIM
CTD
RGD
PMID:12426569 PMID:12746914 PMID:14681301 PMID:15129282 PMID:15266304 More... RGD:1581940, RGD:8548841, RGD:1580417 NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha treatment IEP RGD PMID:20079142 RGD:11561913 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 treatment IMP RGD PMID:22635076 RGD:10412335 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 treatment IEP mRNA, protein:increased expression:myocardium (rat) RGD PMID:16183734 PMID:27121011 RGD:2298758, RGD:11073666 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Mapk1 mitogen activated protein kinase 1 IDA RGD PMID:15653762 RGD:1582282 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 ameliorates ISO RGD PMID:33409963 RGD:401794430 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 ameliorates IEP RGD PMID:28622474 RGD:329333030 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mdh2 malate dehydrogenase 2 IDA RGD PMID:9753871 RGD:1582468 NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271
JBrowse link
G Mdk midkine IEP RGD PMID:9568069 RGD:1582488 NCBI chr 3:77,901,134...77,903,997
Ensembl chr 3:77,901,158...77,903,130
JBrowse link
G Mef2a myocyte enhancer factor 2a ISO RGD PMID:15811259 RGD:1580548 NCBI chr 1:120,847,874...120,982,488
Ensembl chr 1:120,850,080...120,981,948
JBrowse link
G Mef2c myocyte enhancer factor 2C treatment IMP RGD PMID:23948075 RGD:7327215 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Meox2 mesenchyme homeobox 2 IEP protein:decreased expression:heart (rat) RGD PMID:24155330 RGD:155882536 NCBI chr 6:53,856,760...53,917,467
Ensembl chr 6:53,856,758...53,917,467
JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 treatment ISO human gene and cell line in a rat model RGD PMID:32550911 RGD:242905196 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875
JBrowse link
G Mff mitochondrial fission factor treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:23867156 PMID:23867156 RGD:12879458 NCBI chr 9:84,007,798...84,036,039
Ensembl chr 9:84,007,798...84,036,039
JBrowse link
G Mfn2 mitofusin 2 treatment IEP RGD PMID:20886221 RGD:12738232 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mgp matrix Gla protein susceptibility ISO RGD PMID:11073842 RGD:1582503 NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667
JBrowse link
G Mia3 MIA SH3 domain ER export factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198609 NCBI chr13:94,970,421...95,012,071
Ensembl chr13:94,970,424...95,011,972
JBrowse link
G Miat myocardial infarction associated transcript susceptibility ISO CTD Direct Evidence: marker/mechanism CTD
OMIM
PMID:17066261 NCBI chr12:44,414,620...44,429,852 JBrowse link
G Mif macrophage migration inhibitory factor ISO
IEP
protein:increased expression:plasma
mRNA, protein:increased expression:myocardium
RGD PMID:11589847 PMID:12704210 RGD:1642008, RGD:1642003 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Mir125b2 microRNA 125b-2 ISO CTD Direct Evidence: therapeutic CTD PMID:29122578 NCBI chr11:16,245,620...16,245,707 JBrowse link
G Mir143 microRNA 143 ISO
IEP
RNA:increased expression:myocardium:
RNA:increased expression:plasma, left ventricle:
RGD PMID:28887629 PMID:29728596 RGD:155882580, RGD:155882581 NCBI chr18:55,101,006...55,101,110
Ensembl chr18:55,101,006...55,101,110
JBrowse link
G Mir145 microRNA 145 treatment
ameliorates
ISO
IMP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:29956747 PMID:30146700 PMID:32890431 RGD:155260296, RGD:155260294 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727
JBrowse link
G Mir155 microRNA 155 treatment ISO RGD PMID:31207208 RGD:21066347 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mir208a microRNA 208a treatment ISO
IEP
miRNA:increased expression:heart RGD PMID:26688617 PMID:26861724 RGD:11536862, RGD:242905213 NCBI chr15:28,425,570...28,425,652 JBrowse link
G Mir223 microRNA 223 IEP RNA:increased expression:heart RGD PMID:29608885 RGD:21408565 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996
JBrowse link
G Mir25 microRNA 25 ISO RNA:increased expression:myocardium: RGD PMID:28887629 RGD:155882580 NCBI chr12:17,042,932...17,043,015
Ensembl chr12:17,042,932...17,043,015
JBrowse link
G Mir30a microRNA 30a treatment IDA RGD PMID:29849775 RGD:35673318 NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670
JBrowse link
G Mir30c1 microRNA 30c-1 ISO CTD Direct Evidence: therapeutic CTD PMID:34217758 NCBI chr 5:134,349,237...134,349,325
Ensembl chr 5:134,349,237...134,349,325
JBrowse link
G Mir30e microRNA 30e IEP miRNA:decreased expression:heart (rat) RGD PMID:25950484 RGD:11541106 NCBI chr 5:134,352,232...134,352,323
Ensembl chr 5:134,352,232...134,352,323
JBrowse link
G Mir320a microRNA 320a treatment ISO RGD PMID:19380620 RGD:155882541 NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473
JBrowse link
G Mir423 microRNA 423 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24253456 NCBI chr10:61,914,142...61,914,220
Ensembl chr10:61,914,133...61,914,226
JBrowse link
G Mir761 microRNA 761 ISO CTD Direct Evidence: therapeutic CTD PMID:23867156 NCBI chr 5:123,776,534...123,776,609
Ensembl chr 5:123,776,534...123,776,609
JBrowse link
G Mlxipl MLX interacting protein-like susceptibility ISO DNA:SNP:cd: C771G, p.Q241H (rs3812316) (human) RGD PMID:24448738 RGD:401799621 NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112
JBrowse link
G Mmp1 matrix metallopeptidase 1 susceptibility ISO
IEP
IDA
protein:increased expression, increased activity:heart left ventricle (rat)
human gene in rat model
associated with Coronary Artery Disease; DNA:snps, haplotype:promoter:g.-519A>G, g.-340T>C (human)
RGD PMID:15009768 PMID:8531210 PMID:11179039 PMID:19797822 PMID:16210545 RGD:1582535, RGD:7207198, RGD:7207136, RGD:7207135, RGD:1582520 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp13 matrix metallopeptidase 13 IDA RGD PMID:15782494 RGD:1582556 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link
G Mmp14 matrix metallopeptidase 14 IEP
ISO
RGD PMID:10773235 PMID:16461815 RGD:1582587, RGD:1582569 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
JBrowse link
G Mmp2 matrix metallopeptidase 2 IEP
ISO
IDA
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:16310260 PMID:24358288 PMID:10773235 PMID:11179039 RGD:1582587, RGD:7207136 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO RGD PMID:15467919 RGD:1580551 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mmp7 matrix metallopeptidase 7 ISO RGD PMID:16769909 RGD:1582373 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
JBrowse link
G Mmp9 matrix metallopeptidase 9 susceptibility ISO
IEP
IDA
protein:increased expression:coronary artery, plasma (human)
protein:increased expression:heart left ventricle
CTD Direct Evidence: marker/mechanism
protein:increased expression, increased activity:heart left ventricle (rat)
DNA:snps:promoter, exon:g.-1562C>T, p.R279Q (rs3918242, rs2664538) (human)
CTD
RGD
PMID:16310260 PMID:24358288 PMID:15118287 PMID:25520329 PMID:8531210 More... RGD:1582645, RGD:13204799, RGD:7207198, RGD:7207049, RGD:1582639, RGD:1582653 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mstn myostatin ISO mRNA:decreased expression:myocardium (mouse) RGD PMID:32427381 RGD:329849118 NCBI chr 9:48,452,533...48,458,933
Ensembl chr 9:48,452,533...48,458,933
JBrowse link
G Mt-nd2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 ISO DNA:missense mutation: :m.5178C>A (p.L237M) (human) RGD PMID:15262184 RGD:1581054 NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942
JBrowse link
G Mthfr methylenetetrahydrofolate reductase susceptibility ISO associated with Kidney Failure, Chronic; DNA:transition:cds:g.677C>T rs1801133 (human)
DNA:SNP: :677C>T (human)
RGD PMID:19272686 PMID:10090925 RGD:6893548, RGD:10449412 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment IDA protein:decreased serine phosphorylation:heart
associated with Diabetes Mellitus, Experimental
RGD PMID:20352476 PMID:23773982 RGD:10041035, RGD:10041040 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Myh6 myosin heavy chain 6 IEP RGD PMID:15090263 RGD:11565830 NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720
JBrowse link
G Myh7 myosin heavy chain 7 ISO
IEP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:11743230 PMID:15090263 RGD:11565830 NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217
JBrowse link
G Ncam1 neural cell adhesion molecule 1 ISO
IEP
mRNA, protein:increased expression:heart
protein:alternative form, increased expression:myocardium
RGD PMID:19853610 PMID:23462508 RGD:2325979, RGD:40924663 NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014
JBrowse link
G Ndufb5 NADH:ubiquinone oxidoreductase subunit B5 treatment ISO RGD PMID:24692845 RGD:13801194 NCBI chr 2:115,519,248...115,533,589
Ensembl chr 2:115,519,154...115,533,589
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 treatment IDA
ISO
RGD PMID:23290949 PMID:24915518 RGD:10412734, RGD:10412738 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha treatment IEP RGD PMID:19616538 RGD:10413879 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Ngf nerve growth factor treatment ISO protein:increased expression:myocardium RGD PMID:20360245 PMID:20360245 RGD:405100231, RGD:405100231 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Nlk nemo like kinase IEP mRNA, protein:decreased expression:heart RGD PMID:26861724 RGD:242905213 NCBI chr10:63,467,388...63,590,960
Ensembl chr10:63,438,222...63,589,730
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 ameliorates IEP RGD PMID:33389498 RGD:242905187 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nono non-POU domain containing, octamer-binding ameliorates ISO RGD PMID:35247074 RGD:155882458 NCBI chr  X:66,554,131...66,571,992
Ensembl chr  X:66,554,098...66,571,952
JBrowse link
G Nos2 nitric oxide synthase 2 treatment ISO
IEP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:10090345 PMID:11489778 PMID:26192027 RGD:329970290 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility
treatment
ISO
IEP
IDA
DNA:repeats:intron
protein:decreased expression:aorta (rat)
CTD Direct Evidence: marker/mechanism
human gene in rat model
DNA:duplication:intron:IVS4?-?+27 (human)
CTD
RGD
PMID:10510054 PMID:16337503 PMID:10531147 PMID:29311930 PMID:28980197 More... RGD:5128481, RGD:13503346, RGD:13450930, RGD:7771563, RGD:7771561, RGD:1580284, RGD:1580283 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Npm1 nucleophosmin 1 ISO protein:increased expression:cardiomyocyte: RGD PMID:21444791 RGD:11535018 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
JBrowse link
G Nppa natriuretic peptide A ISO
IEP
DNA:snp:cds:c.2238T>C (human)
CTD Direct Evidence: marker/mechanism|therapeutic
CTD
RGD
PMID:9527094 PMID:11743230 PMID:12514664 PMID:16087130 RGD:1579982, RGD:1580000 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Nppb natriuretic peptide B IMP
ISO
IEP
RGD PMID:19858735 PMID:17639095 PMID:17256064 RGD:2324680, RGD:7247724, RGD:1642266 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Npr1 natriuretic peptide receptor 1 susceptibility ISO DNA:missense mutation:cds:p.M341I (human) RGD PMID:14646971 RGD:1580174 NCBI chr 2:175,934,181...175,950,118
Ensembl chr 2:175,934,181...175,949,505
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 susceptibility ISO DNA:SNPs, haplotype:promoter:c.-115G>A, c.-840C>A (rs12221497, rs61896015) (human) RGD PMID:21903943 RGD:401842365 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16413583 PMID:17587755 NCBI chr19:30,715,634...31,059,885
Ensembl chr19:30,715,648...31,059,885
JBrowse link
G Nrg1 neuregulin 1 treatment ISO
IEP
RGD PMID:24200746 PMID:26892146 PMID:27993643 RGD:10449026, RGD:11522702, RGD:405145704 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22503866 NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 susceptibility ISO DNA:missense mutation:cds:p.K167N (human)
ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
OMIM
CTD
RGD
PMID:12646194 PMID:12810610 PMID:14684693 PMID:25741868 PMID:12646194 RGD:1580996 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase treatment IEP RGD PMID:20886221 RGD:12738232 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G Oprd1 opioid receptor, delta 1 IDA
IMP
RGD PMID:12798419 PMID:15076225 RGD:2316587, RGD:9831425 NCBI chr 5:144,306,188...144,340,960
Ensembl chr 5:144,306,188...144,340,960
JBrowse link
G Oprk1 opioid receptor, kappa 1 IMP RGD PMID:15076225 RGD:9831425 NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:13,860,021...13,877,823
JBrowse link
G P2ry12 purinergic receptor P2Y12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19334620 NCBI chr 2:143,481,468...143,523,340
Ensembl chr 2:143,481,430...143,523,361
JBrowse link
G Pappa pappalysin susceptibility ISO DNA:polymorphism:intron
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:11586954 PMID:17700210 RGD:1642324 NCBI chr 5:78,497,660...78,735,873
Ensembl chr 5:78,498,300...78,730,666
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO protein:altered processing:left ventricle (mouse) RGD PMID:21282286 RGD:5684012 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 ISO DNA:SNP:intron: (rs6080699) (human) RGD PMID:20036365 RGD:6483554 NCBI chr 3:130,880,422...131,183,127
Ensembl chr 3:130,880,422...131,183,127
JBrowse link
G Pde3a phosphodiesterase 3A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19027736 NCBI chr 4:174,172,804...174,443,944
Ensembl chr 4:174,172,868...174,438,274
JBrowse link
G Pde5a phosphodiesterase 5A IMP RGD PMID:17339532 RGD:2314468 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
JBrowse link
G Pdgfd platelet derived growth factor D IEP mRNA,protein:altered expression:myocardium: RGD PMID:21767547 RGD:9854703 NCBI chr 8:3,488,448...3,722,395
Ensembl chr 8:3,488,423...3,722,395
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 IEP protein:decreased expression:right heart ventricle, ventricular septum RGD PMID:17089028 RGD:2302667 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 onset
no_association
ISO DNA:polymorphisms: :p.N563S, p.G670R (human)
DNA:missense mutation:cds:p.R643G (human)
DNA:missense mutations:cds:p.L125V, p.S563N (human)
RGD PMID:11795274 PMID:15488875 PMID:15265022 RGD:2311656, RGD:6771224, RGD:1581009 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
JBrowse link
G Pgf placental growth factor ISO
IMP
RGD PMID:20649603 PMID:21329947 PMID:22114497 RGD:6483584, RGD:6483777, RGD:6483773 NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685
JBrowse link
G Phactr1 phosphatase and actin regulator 1 susceptibility
severity
no_association
ISO
IEP
CTD Direct Evidence: marker/mechanism
DNA:SNP:intron: (rs9369640) (human)
DNA:SNPs:multiple (human)
DNA:SNP:intron:(rs12526453) (human)
mRNA:increased expression:peripheral blood mononuclear cells (human)
DNA:SNPs:intron 3: (rs9349379, rs2026458, rs2876300) (human)
DNA:SNP:intron:g.13035530G>C (rs12526453) (human)
mRNA, protein:decreased expression:heart left ventricle (rat)
CTD
RGD
PMID:19198609 PMID:26098115 PMID:25738804 PMID:25838425 PMID:26086777 More... RGD:11052994, RGD:11052493, RGD:11056926, RGD:401900171, RGD:401900171, RGD:401851907, RGD:11053274 NCBI chr17:21,560,364...22,040,166
Ensembl chr17:21,562,721...22,039,831
JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34351043 NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma ISO RGD PMID:20056919 RGD:6482688 NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043
JBrowse link
G Pla2g7 phospholipase A2 group VII ISO protein:decreased expression:serum RGD PMID:19644070 RGD:6482786 NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476
JBrowse link
G Plat plasminogen activator, tissue type treatment ISO DNA:snp:enhancer:g.-7351C>T (human)
CTD Direct Evidence: therapeutic
CTD
RGD
PMID:1430592 PMID:1492007 PMID:1898952 PMID:1899364 PMID:1900011 More... RGD:1580881, RGD:11541077 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
JBrowse link
G Plau plasminogen activator, urokinase ISO
IEP
DNA:SNP:3' utr:c.*141C>T (rs4065) (human)
CTD Direct Evidence: marker/mechanism|therapeutic
mRNA, protein:increased expression:myocardium
CTD
RGD
PMID:1908371 PMID:2174952 PMID:2382605 PMID:3068399 PMID:3984876 More... RGD:6484126, RGD:6484145, RGD:6484133 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO
IEP
mRNA, protein:increased expression:myocardium RGD PMID:12393744 PMID:20952728 RGD:1580897, RGD:6484133 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595
JBrowse link
G Plcb1 phospholipase C beta 1 IEP protein:increased expression:heart RGD PMID:9521338 RGD:2314514 NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869
JBrowse link
G Plcb3 phospholipase C beta 3 IEP protein:increased expression:heart RGD PMID:9521338 RGD:2314514 NCBI chr 1:204,143,257...204,160,384
Ensembl chr 1:204,144,956...204,160,228
JBrowse link
G Pln phospholamban treatment IDA
IEP
ISO
protein:decreased expression:heart left ventricle (rat)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16026515 PMID:16162791 PMID:23781262 PMID:26067684 RGD:7327176, RGD:11097969 NCBI chr20:32,629,537...32,639,559 JBrowse link
G Pon1 paraoxonase 1 ISO RGD PMID:10978258 PMID:10610741 RGD:1580202, RGD:1580198 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Postn periostin IEP protein:increased expression:heart: RGD PMID:24212842 RGD:10041024 NCBI chr 2:138,527,714...138,559,098
Ensembl chr 2:138,527,696...138,559,099
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO DNA:SNP:intron:rs4253623, minor allele associated with increased risk (human) RGD PMID:18549840 RGD:5562819 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IEP
ISO
protein:decreased expression:heart (rat)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:22503866 PMID:22503866 PMID:22087236 RGD:7242181, RGD:6484266 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Prkce protein kinase C, epsilon ISO CTD Direct Evidence: therapeutic
RNA:decreased expression:myocardium:
CTD
RGD
PMID:16782078 PMID:28887629 RGD:155882580 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Prkd1 protein kinase D1 treatment IEP RGD PMID:26064267 RGD:289474908 NCBI chr 6:67,725,193...68,039,002
Ensembl chr 6:67,725,905...68,039,042
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa ISO RGD PMID:10936861 RGD:11100014 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133
JBrowse link
G Psma6 proteasome 20S subunit alpha 6 susceptibility ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Myocardial infarction, susceptibility to
CTD
ClinVar
OMIM
PMID:16845397 PMID:19282875 PMID:25741868 NCBI chr 6:72,765,534...72,796,554
Ensembl chr 6:72,765,473...72,796,554
JBrowse link
G Ptgis prostaglandin I2 synthase susceptibility ISO DNA:SNP::1117C>A (human)
DNA:silent mutation:exon 8:1117C>A (human)
DNA:SNP:CDS: (rs5629) (human)
RGD PMID:19040046 PMID:12040339 PMID:19327107 PMID:19046748 RGD:401901147, RGD:401901268, RGD:401901155, RGD:2313891 NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:15138244 RGD:1581289 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptn pleiotrophin IEP protein:increased expression:myocardium (rat) RGD PMID:17925408 RGD:10044023 NCBI chr 4:65,293,731...65,375,572
Ensembl chr 4:65,293,734...65,375,456
JBrowse link
G Rad50 RAD50 double strand break repair protein treatment IDA RGD PMID:15623426 RGD:9831390 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396
JBrowse link
G Ranbp1 RAN binding protein 1 IEP protein:decreased expression:heart ventricle, cytoplasm (rat) RGD PMID:25341891 RGD:9835001 NCBI chr11:82,742,603...82,750,836
Ensembl chr11:82,742,600...82,750,838
JBrowse link
G Rbp4 retinol binding protein 4 ISO protein:increased expression:blood serum (human) RGD PMID:25142320 RGD:329845867 NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399
JBrowse link
G Reg1a regenerating family member 1 alpha IEP mRNA:increased expression:heart left ventricle (rat) RGD PMID:15778284 RGD:9850130 NCBI chr 4:110,892,451...110,895,115
Ensembl chr 4:110,892,453...110,895,570
JBrowse link
G Ren renin susceptibility ISO associated with Hypertension; protein:increased activity:plasma (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:1668233 PMID:1759997 RGD:6892687 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Retn resistin ISO protein:increased expression:plasma RGD PMID:18997620 RGD:7207152 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 IEP protein:increased threonine phosphorylation:heart left ventricle RGD PMID:16540832 RGD:1642998 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Ryr1 ryanodine receptor 1 IDA protein:hyperphosphorylation:extensor digitorum longus: RGD PMID:12824280 RGD:329813076 NCBI chr 1:84,292,578...84,423,824
Ensembl chr 1:84,292,578...84,423,812
JBrowse link
G S100b S100 calcium binding protein B IEP
ISO
mRNA, protein:increased expression:left ventricle myocardium, plasma
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:9788975 PMID:19910580 RGD:2325647 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743
JBrowse link
G Sdc1 syndecan 1 IEP mRNA:increased expression:myocardium RGD PMID:9237025 RGD:2311712 NCBI chr 6:31,562,799...31,585,267
Ensembl chr 6:31,562,739...31,585,264
JBrowse link
G Sdc4 syndecan 4 ISO protein:increased expression:plasma RGD PMID:11372670 RGD:2312328 NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580
JBrowse link
G Sell selectin L ISO CTD Direct Evidence: marker/mechanism CTD PMID:10070497 NCBI chr13:76,416,969...76,436,444
Ensembl chr13:76,416,915...76,436,456
JBrowse link
G Selp selectin P susceptibility ISO
IEP
associated with Hypertension;protein:increased expression:plasma
protein:increased expression:serum
DNA:polymorphisms, haplotypes:cds:p.S290N, p.N562D, p.T715P (human)
RGD PMID:17391113 PMID:21162967 PMID:21567088 PMID:12165563 RGD:2312304, RGD:6219003, RGD:6218991, RGD:1580075 NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845
JBrowse link
G Serpine1 serpin family E member 1 susceptibility ISO
IMP
DNA:deletion:promoter:g.-676_-674delG (human) RGD PMID:12477941 PMID:16053971 RGD:1626626, RGD:8547882 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 IEP
ISO
RGD PMID:19109969 PMID:19079247 RGD:4107088, RGD:155883169 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
JBrowse link
G Sh2b3 SH2B adaptor protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198610 NCBI chr12:34,731,934...34,753,617
Ensembl chr12:34,731,911...34,753,616
JBrowse link
G Shh sonic hedgehog signaling molecule treatment IMP RGD PMID:20052412 RGD:12879408 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Sirt1 sirtuin 1 IEP protein:altered localization:nucleus RGD PMID:20089851 RGD:2316169 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Sirt3 sirtuin 3 treatment IEP RGD PMID:24471974 RGD:9586050 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808
JBrowse link
G Slc27a1 solute carrier family 27 member 1 IEP protein:decreased expression:infarcted heart RGD PMID:17034771 RGD:1642800 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
JBrowse link
G Slc27a6 solute carrier family 27 member 6 IEP protein:decreased expression:heart RGD PMID:17034771 RGD:1642800 NCBI chr18:52,040,241...52,099,622
Ensembl chr18:52,041,074...52,099,414
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor treatment IEP RGD PMID:23361363 RGD:9999400 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
JBrowse link
G Smad2 SMAD family member 2 treatment
ameliorates
IEP
ISO
RGD PMID:11087260 PMID:33409963 RGD:12903276, RGD:401794430 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
JBrowse link
G Smad3 SMAD family member 3 ameliorates ISO RGD PMID:33409963 RGD:401794430 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Smad4 SMAD family member 4 treatment IEP RGD PMID:11087260 RGD:12903276 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Socs1 suppressor of cytokine signaling 1 IEP protein:increased expression:heart RGD PMID:16377761 RGD:2298918 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
JBrowse link
G Sod1 superoxide dismutase 1 treatment ISO CTD Direct Evidence: therapeutic
human gene in a rat model
CTD
RGD
PMID:21600015 PMID:11864929 PMID:22006090 RGD:1581222, RGD:8655953 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 IDA
ISO
IEP
CTD Direct Evidence: therapeutic CTD
RGD
PMID:12160945 PMID:14575298 PMID:9250167 RGD:1581148, RGD:1580839 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sod3 superoxide dismutase 3 ISO RGD PMID:14592844 RGD:1580841 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Sparc secreted protein acidic and cysteine rich IEP mRNA:increased expression:heart RGD PMID:12826287 RGD:2300056 NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:12939547 PMID:14500723 RGD:1581386, RGD:1581325 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 treatment IDA protein:increased phosphorylation:heart left ventricle(rat) RGD PMID:26067684 RGD:11097969 NCBI chr10:72,838,926...72,859,066
Ensembl chr10:72,839,274...72,845,336
JBrowse link
G Tbx3 T-box transcription factor 3 IEP RGD PMID:19341743 RGD:5132891 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708
JBrowse link
G Tbx5 T-box transcription factor 5 treatment IMP RGD PMID:23948075 RGD:7327215 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885
JBrowse link
G Tek TEK receptor tyrosine kinase IEP protein:increased expression:ventricle myocardium RGD PMID:16714360 RGD:1601493 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804
JBrowse link
G Tfpi tissue factor pathway inhibitor treatment ISO
IEP
mRNA,protein:increased expression:heart: RGD PMID:15630488 PMID:21229253 PMID:14656922 RGD:11060131, RGD:11062083, RGD:11060139 NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880
JBrowse link
G Tgfb1 transforming growth factor, beta 1 susceptibility ISO
IEP
associated with Coronary Disease;DNA:polymorphism:promoter:-509C>T (human)
CTD Direct Evidence: marker/mechanism
mRNA,protein:increased expression:heart:
CTD
RGD
PMID:16310260 PMID:16543493 PMID:27121011 PMID:15118671 RGD:1601560, RGD:11073666, RGD:1331525 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb2 transforming growth factor, beta 2 IEP RGD PMID:14575314 RGD:2302107 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 IEP RGD PMID:10198196 RGD:1601617 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 IEP protein:increased expression:myocardium RGD PMID:10198196 RGD:1601617 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Th tyrosine hydroxylase no_association ISO DNA:polymorphism:intron:g.1170_1173dupTCAT (human) RGD PMID:16139102 RGD:1580048 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Thbd thrombomodulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:9843165 PMID:10627464 NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193
JBrowse link
G Thbs1 thrombospondin 1 IEP mRNA, protein:increased expression:myocardium RGD PMID:16179730 RGD:2317960 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24358288 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
JBrowse link
G Tlr4 toll-like receptor 4 ISO DNA:SNP:intron:rs1927911, minor allele associated with decreased risk (human) RGD PMID:15864121 PMID:18549840 RGD:1580734, RGD:5562819 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tm6sf2 transmembrane 6 superfamily member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24633158 NCBI chr16:19,344,218...19,351,431
Ensembl chr16:19,344,222...19,351,431
JBrowse link
G Tnc tenascin C IEP protein:increased expression:heart, fibroblast RGD PMID:11454990 RGD:4889618 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
JBrowse link
G Tnf tumor necrosis factor IEP
ISO
mRNA, protein:increased expression:left ventricle myocardium, plasma
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:15883752 PMID:16310260 PMID:21362018 RGD:5130892 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B ISO RGD PMID:15926884 RGD:1620893 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A ISO CTD Direct Evidence: marker/mechanism CTD PMID:20082609 NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045
JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 IEP protein:increased expression:heart, cardiomyocyte, endothelial cell (rat) RGD PMID:18353719 RGD:2317281 NCBI chr 5:165,486,069...165,494,421
Ensembl chr 5:165,484,262...165,493,703
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A IEP
IMP
IDA
mRNA, protein:increased expression:left ventricle myocardium (rat) RGD PMID:21362018 PMID:20651834 PMID:15117889 RGD:5130892, RGD:5130975, RGD:1624194 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B IEP mRNA, protein:decreased expression:left ventricle myocardium (rat) RGD PMID:21362018 RGD:5130892 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
JBrowse link
G Tnfsf11 TNF superfamily member 11 ISO protein:increased expression:serum RGD PMID:18298349 RGD:2302363 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445
JBrowse link
G Tnfsf4 TNF superfamily member 4 susceptibility ISO CTD Direct Evidence: marker/mechanism CTD
OMIM
RGD
PMID:15750594 RGD:1580396 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788
JBrowse link
G Tnni3 troponin I3, cardiac type ISO CTD Direct Evidence: marker/mechanism CTD PMID:12359538 NCBI chr 1:69,299,900...69,303,582
Ensembl chr 1:69,299,900...69,303,580
JBrowse link
G Tnnt2 troponin T2, cardiac type ISO RGD PMID:15226628 RGD:1580441 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388
JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24358288 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 ameliorates
disease_progression
ISO
IMP
RGD PMID:25840803 PMID:25840803 PMID:25840803 RGD:127284842, RGD:127284842, RGD:127284842 NCBI chr 9:12,763,819...12,779,285
Ensembl chr 9:12,763,819...12,779,203
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 IMP RGD PMID:27671317 RGD:13792689 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
JBrowse link
G Trpv1em1Sage transient receptor potential cation channel, subfamily V, member 1; ZFN induced mutant 1, Sage IMP RGD PMID:27671317 RGD:13792689
G Ttn titin IEP RGD PMID:12221049 RGD:1580780 NCBI chr 3:61,652,432...61,924,912
Ensembl chr 3:61,652,439...61,924,741
JBrowse link
G Txn1 thioredoxin 1 ISO RGD PMID:14677813 RGD:1580785 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
G Txnrd1 thioredoxin reductase 1 IEP mRNA:decreased expression:heart left ventricle (rat) RGD PMID:18515646 RGD:5134341 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Ubd ubiquitin D IEP
IMP
mRNA, protein; increased expression; myocardium (rat)
associated with induced myocardial infarction
RGD PMID:29438664 PMID:29438664 RGD:126925221, RGD:126925221 NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639
JBrowse link
G Ubdem1 ubiquitin D; CRISPR/Cas9 induced mutant1 IMP associated with induced myocardial infarction RGD PMID:29438664 RGD:126925221
G Uts2 urotensin 2 IEP associated with Heart Failure, Congestive;mRNA:increased expression:heart ventricle RGD PMID:15549273 RGD:2306846 NCBI chr 5:161,450,846...161,456,235
Ensembl chr 5:161,450,846...161,456,237
JBrowse link
G Uts2r urotensin 2 receptor IEP associated with Heart Failure, Congestive;mRNA:increased expression:heart ventricle RGD PMID:15549273 RGD:2306846 NCBI chr10:106,438,092...106,439,252
Ensembl chr10:106,438,092...106,439,252
JBrowse link
G Vcan versican IEP RGD PMID:16311904 RGD:1598497 NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637
JBrowse link
G Vdac1 voltage-dependent anion channel 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25488258 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
JBrowse link
G Vdac2 voltage-dependent anion channel 2 treatment IDA RGD PMID:20601275 RGD:10003049 NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553
JBrowse link
G Vegfa vascular endothelial growth factor A treatment ISO
IDA
protein:increased expression:serum,platelet: RGD PMID:10652191 PMID:25936512 RGD:7483604, RGD:126925214 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vegfb vascular endothelial growth factor B ISO RGD PMID:17975666 RGD:2314324 NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944
JBrowse link
G Vwf von Willebrand factor IEP protein:increased expression:heart: RGD PMID:19435557 RGD:11080745 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539
JBrowse link
G Wdr12 WD repeat domain 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19198609 PMID:25915632 NCBI chr 9:61,475,498...61,502,762
Ensembl chr 9:61,475,517...61,502,469
JBrowse link
G Wrn WRN RecQ like helicase ISO RGD PMID:9021029 RGD:1580821 NCBI chr16:58,763,517...58,898,604
Ensembl chr16:58,763,504...58,895,450
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 susceptibility ISO DNA:polymorphism:: (human) RGD PMID:18712175 RGD:401827276 NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444
JBrowse link
G Ybx1 Y box binding protein 1 IEP RGD PMID:16002047 RGD:1580630 NCBI chr 5:132,882,137...132,898,885
Ensembl chr 5:132,882,145...132,898,862
JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 IEP protein:increased expression:heart (rat) RGD PMID:24155330 RGD:155882536 NCBI chr 3:29,214,581...29,344,890
Ensembl chr 3:29,218,301...29,345,157
JBrowse link
acute myocardial infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgap17 Rho GTPase activating protein 17 ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr 1:177,807,579...177,897,027
Ensembl chr 1:177,807,583...177,896,854
JBrowse link
G Bax BCL2 associated X, apoptosis regulator ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G C3 complement C3 ISO RGD PMID:26476955 RGD:11552746 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 ISO mRNA:decreased expression:blood: RGD PMID:27746059 RGD:13524557 NCBI chr10:92,683,778...92,745,842
Ensembl chr10:92,683,761...92,746,126
JBrowse link
G Casp3 caspase 3 treatment IEP RGD PMID:26550220 RGD:13782284 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 treatment IEP RGD PMID:26550220 RGD:13782284 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Ccn1 cellular communication network factor 1 ameliorates ISO RGD PMID:30371213 RGD:329845516 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Dsc2 desmocollin 2 ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr18:11,450,392...11,482,476
Ensembl chr18:11,450,390...11,482,392
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit treatment IEP RGD PMID:23054911 RGD:405650598 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fto FTO, alpha-ketoglutarate dependent dioxygenase ISO mRNA:increased expression:blood RGD PMID:35693610 RGD:329901852 NCBI chr19:15,284,898...15,692,142
Ensembl chr19:15,349,696...15,692,083
JBrowse link
G Gata5 GATA binding protein 5 susceptibility ISO DNA:SNPs:promoter:rs80197101, rs77067995 (human) RGD PMID:33684162 RGD:155260335 NCBI chr 3:167,418,563...167,426,751
Ensembl chr 3:167,418,565...167,426,751
JBrowse link
G Gp6 glycoprotein VI ameliorates
sexual_dimorphism
ISO DNA:missense mutation:CDS:p.S219P (rs1613662) (human)
DNA:missense mutation:intron 1, intron 5: (rs1671207, rs11084382) (human)
RGD PMID:20227257 PMID:20227257 RGD:401794138, RGD:401794138 NCBI chr 1:69,429,232...69,492,709
Ensembl chr 1:69,465,789...69,491,326
JBrowse link
G Gpx3 glutathione peroxidase 3 ISO protein:increased expression:plasma RGD PMID:28374671 RGD:401827832 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment
ameliorates
IEP RGD PMID:26591365 PMID:32068187 RGD:13792778, RGD:267358468 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G H19 H19 imprinted maternally expressed transcript ameliorates IMP RGD PMID:31755219 RGD:213230161 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 ISO ClinVar Annotator: match by term: Acute myocardial infarction ClinVar PMID:20946881 PMID:21250968 PMID:21596855 PMID:21997850 PMID:22160010 More... NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Ifng interferon gamma ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499
JBrowse link
G Il10 interleukin 10 ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il17a interleukin 17A ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il1b interleukin 1 beta ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 IEP RGD PMID:24837094 RGD:40813741 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256
JBrowse link
G Il33 interleukin 33 IEP RGD PMID:24837094 RGD:40813741 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
JBrowse link
G Il4 interleukin 4 ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Itgam integrin subunit alpha M treatment ISO RGD PMID:21238619 RGD:329901664 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Kif6 kinesin family member 6 ISO DNA:SNP: :p.W719R (rs20455) (human) RGD PMID:20044086 RGD:243048455 NCBI chr 9:11,076,203...11,373,205
Ensembl chr 9:11,072,824...11,373,006
JBrowse link
G Mir126a microRNA 126a disease_progression ISO RGD PMID:36523365 PMID:32595526 RGD:401851047, RGD:401851053 NCBI chr 3:9,415,063...9,415,180
Ensembl chr 3:9,415,063...9,415,180
JBrowse link
G Mir146a microRNA 146a ISO miRNA:increased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
JBrowse link
G Mir155 microRNA 155 ISO miRNA:decreased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mir17 microRNA 17 treatment IMP RGD PMID:29536180 RGD:329403057 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712
JBrowse link
G Mir21 microRNA 21 ISO miRNA:increased expression:peripheral blood mononuclear cell, plasma
RNA:decreased expression:serum
RGD PMID:31866771 PMID:32595526 RGD:21081515, RGD:401851053 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mir223 microRNA 223 treatment IMP RGD PMID:29689569 RGD:25823140 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996
JBrowse link
G Mir320a microRNA 320a ISO RGD PMID:29990866 RGD:155882565 NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Ndufb5 NADH:ubiquinone oxidoreductase subunit B5 ameliorates IEP associated with obesity RGD PMID:35257523 RGD:401794445 NCBI chr 2:115,519,248...115,533,589
Ensembl chr 2:115,519,154...115,533,589
JBrowse link
G Pf4 platelet factor 4 treatment IEP RGD PMID:29407168 RGD:329901925 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Plcg1 phospholipase C, gamma 1 ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
JBrowse link
G Ppbp pro-platelet basic protein treatment IEP RGD PMID:29407168 RGD:329901925 NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130
JBrowse link
G Pten phosphatase and tensin homolog ameliorates IEP
ISO
mRNA:decreased expression:heart left ventricle (rat)
RNA:increased expression:serum
RGD PMID:26973267 PMID:32595526 PMID:29990866 RGD:11526378, RGD:401851053, RGD:155882565 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Rhoa ras homolog family member A ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rit2 Ras-like without CAAX 2 ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr18:22,565,403...22,921,648
Ensembl chr18:22,565,404...22,921,648
JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B ameliorates IEP associated with obesity RGD PMID:35257523 RGD:401794445 NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293
JBrowse link
G Serping1 serpin family G member 1 ISO
IEP
mRNA:increased expression:heart RGD PMID:26476955 PMID:26476955 RGD:11552746, RGD:11552746 NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034
JBrowse link
G Tbx1 T-box transcription factor 1 treatment IEP RGD PMID:27422448 RGD:155882497 NCBI chr11:82,409,275...82,419,058
Ensembl chr11:82,409,275...82,418,380
JBrowse link
G Tnf tumor necrosis factor ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214
JBrowse link
anterolateral myocardial infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 ISO protein:increased expression:aortic root, coronary sinus, plasma (human) RGD PMID:12581682 RGD:8661757 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Serpine1 serpin family E member 1 disease_progression ISO protein:decreased expression, decreased activity:heart: RGD PMID:12615902 PMID:12615902 RGD:13208541, RGD:13208541 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
Cardiogenic Shock term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epo erythropoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19337937 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: therapeutic CTD PMID:1430592 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21062213 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
Coronary Artery Disease, Autosomal Dominant 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mef2a myocyte enhancer factor 2a ISO ClinVar Annotator: match by term: Coronary artery disease, autosomal dominant, 1 | ClinVar Annotator: match by term: Coronary artery disease/myocardial infarction
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:14645853 PMID:15496429 PMID:15841183 PMID:25741868 NCBI chr 1:120,847,874...120,982,488
Ensembl chr 1:120,850,080...120,981,948
JBrowse link
Coronary Artery Disease, Autosomal Dominant 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase ISO ClinVar Annotator: match by term: Coronary artery disease, autosomal dominant 2 ClinVar PMID:25741868 PMID:28492532 NCBI chr 6:25,292,133...25,315,078
Ensembl chr 6:25,292,133...25,319,861
JBrowse link
G Lrp6 LDL receptor related protein 6 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Coronary artery disease, autosomal dominant 2
OMIM
CTD
ClinVar
PMID:17332414 PMID:23703864 PMID:25741868 PMID:28492532 NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
myocardial stunning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16317512 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11927517 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Pln phospholamban ISO CTD Direct Evidence: marker/mechanism CTD PMID:16317512 NCBI chr20:32,629,537...32,639,559 JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:11927517 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
No-Reflow Phenomenon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdh5 cadherin 5 ISO CTD Direct Evidence: therapeutic CTD PMID:16824628 NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368
JBrowse link
G Ctnnb1 catenin beta 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16824628 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Jup junction plakoglobin ISO CTD Direct Evidence: therapeutic CTD PMID:16824628 NCBI chr10:85,300,438...85,327,378
Ensembl chr10:85,300,440...85,327,057
JBrowse link
ST Elevation Myocardial Infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A treatment ISO DNA:SNPs: :rs1045642,rs7779562(human) RGD PMID:25217066 RGD:14700903 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Atp5mc2 ATP synthase membrane subunit c locus 2 severity ISO RGD PMID:27441480 RGD:14696800 NCBI chr 7:133,791,341...133,799,713
Ensembl chr 7:133,791,342...133,799,733
JBrowse link
G Ccn1 cellular communication network factor 1 sexual_dimorphism ISO protein:increased expression:blood serum (human) RGD PMID:34597881 RGD:329845519 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Lgals3 galectin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29769800 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
JBrowse link
G Mir208a microRNA 208a severity IEP miRNA:increased expression:blood RGD PMID:32458401 RGD:213230165 NCBI chr15:28,425,570...28,425,652 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19076
    disease of anatomical entity 18367
      cardiovascular system disease 5563
        vascular disease 4073
          Myocardial Ischemia 948
            myocardial infarction 442
              Cardiogenic Shock 3
              Coronary Artery Disease, Autosomal Dominant 1 1
              Coronary Artery Disease, Autosomal Dominant 2 2
              No-Reflow Phenomenon 3
              Non-ST Elevated Myocardial Infarction 0
              ST Elevation Myocardial Infarction 5
              acute myocardial infarction + 47
              anterolateral myocardial infarction + 2
              apical myocardial infarction 0
              inferior myocardial infarction 0
              inferolateral myocardial infarct 0
              lateral myocardial infarction 0
              myocardial stunning 4
              posterior myocardial infarction 0
              posteroinferior myocardial infarction 0
              posterolateral myocardial infarction 0
              septal myocardial infarction 0
              silent myocardial infarction 0
              subendocardial myocardial infarction 0
Path 2
Term Annotations click to browse term
  disease 19076
    disease of anatomical entity 18367
      cardiovascular system disease 5563
        vascular disease 4073
          ischemia 1500
            Myocardial Ischemia 948
              Coronary Disease 626
                coronary artery disease 600
                  myocardial infarction 442
                    Cardiogenic Shock 3
                    Coronary Artery Disease, Autosomal Dominant 1 1
                    Coronary Artery Disease, Autosomal Dominant 2 2
                    No-Reflow Phenomenon 3
                    Non-ST Elevated Myocardial Infarction 0
                    ST Elevation Myocardial Infarction 5
                    acute myocardial infarction + 47
                    anterolateral myocardial infarction + 2
                    apical myocardial infarction 0
                    inferior myocardial infarction 0
                    inferolateral myocardial infarct 0
                    lateral myocardial infarction 0
                    myocardial stunning 4
                    posterior myocardial infarction 0
                    posteroinferior myocardial infarction 0
                    posterolateral myocardial infarction 0
                    septal myocardial infarction 0
                    silent myocardial infarction 0
                    subendocardial myocardial infarction 0
paths to the root