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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:pancreatic acinar cell adenocarcinoma
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Accession:DOID:5742 term browser browse the term
Definition:A pancreatic adenocarcinoma that has_material_basis_in cells with morphological resemblance to acinar cells and is associated with increased serum lipase. (DO)
Synonyms:exact_synonym: pancreatic acinar cell carcinoma
 xref: EFO:1000439;   MONDO:0006346;   NCI:C7977
For additional species annotation, visit the Alliance of Genome Resources.



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pancreatic acinar cell adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO DNA:missense mutation, gene fusions:multiple (human) RGD PMID:25266736 RGD:13462041 NCBI chr 4:69,329,772...69,476,931
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase disease_progression IEP RGD PMID:8569183 RGD:150523792 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:146,091,841...146,139,476
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19141
    disease of cellular proliferation 7891
      cancer 5720
        cell type cancer 3783
          carcinoma 3274
            adenocarcinoma 1700
              acinar cell carcinoma 3
                pancreatic acinar cell adenocarcinoma 2
                  acinar cell cystadenocarcinoma 0
Path 2
Term Annotations click to browse term
  disease 19141
    disease of cellular proliferation 7891
      Neoplasms by Site 7333
        organ system cancer 5468
          endocrine gland cancer 2612
            pancreatic cancer 421
              malignant exocrine pancreas neoplasm 180
                pancreatic carcinoma 179
                  pancreatic adenocarcinoma 60
                    pancreatic acinar cell adenocarcinoma 2
                      acinar cell cystadenocarcinoma 0
paths to the root