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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:testicular germ cell cancer
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Accession:DOID:5557 term browser browse the term
Definition:A testicular cancer that has_material_basis_in germ cells. (DO)
Synonyms:exact_synonym: germ cell tumor of testis;   malignant testicular germ cell neoplasm
 related_synonym: testicular germ cell neoplasm
 xref: EFO:0004281;   MONDO:0003510;   NCI:C8591;   ORDO:3636504
For additional species annotation, visit the Alliance of Genome Resources.


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testicular germ cell cancer term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr3 fibroblast growth factor receptor 3 ISO ClinVar Annotator: match by term: Germ cell tumor of testis ClinVar PMID:1908846 PMID:7647778 PMID:7649548 PMID:7670477 PMID:7702086 More... NCBI chr14:81,211,800...81,227,215
Ensembl chr14:81,211,800...81,227,209 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase ISO ClinVar Annotator: match by term: Germ cell tumor of testis ClinVar PMID:10362788 PMID:25741868 PMID:26822237 PMID:28492532 PMID:28724667 More... NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,903,033...32,978,812 		JBrowse link
G Stk11 serine/threonine kinase 11 ISO ClinVar Annotator: match by term: Germ cell tumor of testis ClinVar PMID:12552571 PMID:17404884 PMID:19340305 PMID:23555315 PMID:23893923 More... NCBI chr 7:10,225,204...10,241,965
Ensembl chr 7:10,225,204...10,241,965 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14566
    disease of cellular proliferation 5586
      cancer 4230
        cell type cancer 2903
          germ cell cancer 119
            testicular germ cell cancer 3
              childhood testicular germ cell tumor 0
              testicular germ cell tumor non-seminomatous 0
              testicular malignant germ cell cancer + 0
              testicular pure germ cell tumor 0
Path 2
Term Annotations click to browse term
  disease 14566
    disease of anatomical entity 13676
      Urogenital Diseases 4547
        Male Urogenital Diseases 1978
          male reproductive system disease 1978
            testicular disease 172
              Testicular Neoplasms 44
                testicular cancer 7
                  testicular germ cell cancer 3
                    childhood testicular germ cell tumor 0
                    testicular germ cell tumor non-seminomatous 0
                    testicular malignant germ cell cancer + 0
                    testicular pure germ cell tumor 0
paths to the root