Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:pancreatitis
go back to main search page
Accession:DOID:4989 term browser browse the term
Definition:A pancreas disease that is characterized by inflammation of the pancreas. (DO)
Synonyms:exact_synonym: pancreatitides
 narrow_synonym: RECURRENT PANCREATITIS;   aggressive insulitis;   benign insulitis;   non-alcoholic pancreatitis;   thiopurine immunosuppressant-induced pancreatitis
 primary_id: MESH:D010195
 xref: EFO:0000278;   EFO:0002498;   EFO:0002502;   EFO:0006315;   EFO:0021524;   ICD10CM:K85.9;   NCI:C3306
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
pancreatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17169977 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865 		JBrowse link
G Bdkrb2 bradykinin receptor B2 IMP RGD PMID:7791078 RGD:4891025 NCBI chr 6:130,237,055...130,267,205
Ensembl chr 6:130,237,255...130,267,209 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like IEP mRNA, protein:increased expression:lung RGD PMID:14530762 RGD:7483579 NCBI chr15:45,350,081...45,373,213
Ensembl chr15:45,334,537...45,373,282 		JBrowse link
G Camp cathelicidin antimicrobial peptide IEP protein:decreased expression:pancreatic islet RGD PMID:26370175 RGD:441221244 NCBI chr 8:118,720,184...118,721,998
Ensembl chr 8:118,720,184...118,721,998 		JBrowse link
G Casp12 caspase 12 IEP RGD PMID:16574987 RGD:2311467 NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:10,926,994...10,954,442 		JBrowse link
G Casp3 caspase 3 IEP RGD PMID:16574987 RGD:2311467 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Cck cholecystokinin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16187300 PMID:16499907 NCBI chr 8:130,031,012...130,037,702
Ensembl chr 8:130,031,013...130,037,686 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP
ISO
IMP 		human gene in rat model RGD PMID:19111613 PMID:16284287 PMID:18297440 RGD:2307002, RGD:8549548, RGD:2307046 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO
IEP 		associated with Pancreatic Neoplasms;DNA:polymorphism: :-403G>A (human)
protein:increased expression:pancreas (rat) 		RGD PMID:16614115 PMID:16843865 RGD:2317568, RGD:2307146 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884 		JBrowse link
G Cd14 CD14 molecule ISO RGD PMID:19201771 RGD:4144143 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292 		JBrowse link
G Cftr CF transmembrane conductance regulator ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Pancreatitis | ClinVar Annotator: match by term: Recurrent pancreatitis 		CTD
ClinVar		 PMID:1370875 PMID:1377276 PMID:1379210 PMID:1379413 PMID:1380673 More... NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643 		JBrowse link
G Cldn2 claudin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143602 NCBI chr  X:108,248,383...108,258,847
Ensembl chr  X:108,237,676...108,262,377 		JBrowse link
G Cnr1 cannabinoid receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17484889 NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:53,204,260...53,239,252 		JBrowse link
G Cnr2 cannabinoid receptor 2 IEP
ISO 		protein:decreased expression:pancreas, acinar cell
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:17484889 PMID:19070664 RGD:2316197 NCBI chr 5:153,408,968...153,435,092
Ensembl chr 5:153,409,147...153,435,961 		JBrowse link
G Cpa1 carboxypeptidase A1 ISS OMIM:167800 MouseDO NCBI chr 4:60,224,801...60,230,928
Ensembl chr 4:60,224,801...60,230,928 		JBrowse link
G Ctrb1 chymotrypsinogen B1 IEP mRNA, protein:decreased expression:pancreas RGD PMID:1716058 RGD:2303363 NCBI chr19:56,562,220...56,566,978
Ensembl chr19:56,562,220...56,566,978 		JBrowse link
G Ctsl cathepsin L IEP protein:altered processing:pancreas (rat) RGD PMID:19805911 RGD:2315546 NCBI chr17:770,104...776,266
Ensembl chr17:770,093...777,113 		JBrowse link
G Dusp1 dual specificity phosphatase 1 IEP mRNA:increased expression:pancreas RGD PMID:11027531 RGD:2301725 NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644 		JBrowse link
G Dusp10 dual specificity phosphatase 10 IEP mRNA:increased expression:pancreas RGD PMID:11027531 RGD:2301725 NCBI chr13:98,145,317...98,183,304
Ensembl chr13:98,145,893...98,183,304 		JBrowse link
G Dusp6 dual specificity phosphatase 6 IEP mRNA:increased expression:pancreas RGD PMID:11027531 RGD:2301725 NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:35,977,921...35,983,833 		JBrowse link
G Egf epidermal growth factor ISO protein:decreased expression:serum RGD PMID:20127414 RGD:2317638 NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297 		JBrowse link
G Egr1 early growth response 1 IEP mRNA, protein:increased expression:pancreas (rat) RGD PMID:16124058 RGD:5131939 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843 		JBrowse link
G Fdx1 ferredoxin 1 IEP mRNA:increased expression:pancreatic acinar cell (rat) RGD PMID:12709512 RGD:4145666 NCBI chr 8:61,164,839...61,183,645
Ensembl chr 8:61,164,839...61,183,583 		JBrowse link
G Fga fibrinogen alpha chain IEP protein:increased expression:pancreas, rough endoplasmic reticulum RGD PMID:19954227 RGD:5688770 NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:170,672,012...170,679,577 		JBrowse link
G Fgb fibrinogen beta chain IEP protein:increased expression:pancreas, rough endoplasmic reticulum RGD PMID:19954227 RGD:5688770 NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:170,692,965...170,705,434 		JBrowse link
G Fgg fibrinogen gamma chain IEP protein:increased expression:pancreas, rough endoplasmic reticulum RGD PMID:19954227 RGD:5688770 NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:170,652,234...170,661,170 		JBrowse link
G Hgf hepatocyte growth factor ISO CTD Direct Evidence: therapeutic CTD PMID:14751415 NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 IEP mRNA:increased expression:lung (rat) RGD PMID:19346995 RGD:5686868 NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:22,931,070...22,935,926 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IDA RGD PMID:16183055 RGD:1624393 NCBI chr15:56,360,647...56,428,703
Ensembl chr15:56,359,596...56,431,619 		JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment ISO
IEP 		protein:increased expression:serum RGD PMID:12923961 PMID:23125085 RGD:2325163, RGD:8547728 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta treatment ISO RGD PMID:17525799 RGD:10045954 NCBI chr16:76,021,968...76,075,717
Ensembl chr16:76,022,008...76,081,911 		JBrowse link
G Il13 interleukin 13 IEP
ISO 		protein:increased expression:pancreas RGD PMID:20100461 PMID:20100461 RGD:4145466, RGD:4145466 NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483 		JBrowse link
G Il15 interleukin 15 IDA RGD PMID:20332642 RGD:4892671 NCBI chr19:42,536,160...42,611,349
Ensembl chr19:42,545,346...42,611,348 		JBrowse link
G Il18 interleukin 18 treatment IEP protein:increased expression:serum RGD PMID:19238530 PMID:23983797 RGD:4889404, RGD:8655988 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286 		JBrowse link
G Il1b interleukin 1 beta IDA RGD PMID:23070084 RGD:7204440 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Ins2 insulin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17163263 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805 		JBrowse link
G Itgb2 integrin subunit beta 2 ISO RGD PMID:22490516 RGD:6482196 NCBI chr20:11,061,009...11,097,242
Ensembl chr20:11,058,492...11,097,182 		JBrowse link
G Klk1 kallikrein 1 IEP protein:increased expression:pancreas RGD PMID:12770935 RGD:1641805 NCBI chr 1:103,779,152...103,783,270
Ensembl chr 1:103,779,164...103,783,270 		JBrowse link
G Lepr leptin receptor IAGP DNA:missense mutation:CDS:p.Q269P (rat) RGD PMID:21836382 RGD:10412020 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215 		JBrowse link
G Lpl lipoprotein lipase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18936103 NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 severity ISO RGD PMID:28090569 RGD:13838805 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase IEP mRNA:increased expression:pancreas (rat) RGD PMID:11737224 RGD:2317606 NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821 		JBrowse link
G Mir100 microRNA 100 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr 8:50,798,295...50,798,374
Ensembl chr 8:50,798,295...50,798,374 		JBrowse link
G Mir130a microRNA 130a ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr 3:90,229,228...90,229,315 JBrowse link
G Mir130b microRNA 130b ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr11:97,384,380...97,384,461
Ensembl chr11:97,384,380...97,384,461 		JBrowse link
G Mir141 microRNA 141 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr 4:159,209,525...159,209,618 JBrowse link
G Mir148a microRNA 148a ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr 4:81,664,431...81,664,527 JBrowse link
G Mir150 microRNA 150 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr 1:104,741,487...104,741,571
Ensembl chr 1:104,741,487...104,741,571 		JBrowse link
G Mir155 microRNA 155 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr11:37,261,114...37,261,178
Ensembl chr11:37,261,114...37,261,178 		JBrowse link
G Mir181c microRNA 181c ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr19:40,888,291...40,888,396
Ensembl chr19:40,888,291...40,888,396 		JBrowse link
G Mir181d microRNA 181d ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr19:40,888,474...40,888,556
Ensembl chr19:40,888,474...40,888,556 		JBrowse link
G Mir182 microRNA 182 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr 4:59,752,246...59,752,307 JBrowse link
G Mir183 microRNA 183 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr 4:59,756,044...59,756,153 JBrowse link
G Mir192 microRNA 192 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr 1:212,994,209...212,994,318
Ensembl chr 1:212,994,209...212,994,318 		JBrowse link
G Mir200a microRNA 200a ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr 5:171,930,717...171,930,805 JBrowse link
G Mir200b microRNA 200b ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr 5:171,931,495...171,931,589 JBrowse link
G Mir200c microRNA 200c ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr 4:159,209,965...159,210,033 JBrowse link
G Mir20b microRNA 20b ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr  X:137,343,197...137,343,268 JBrowse link
G Mir214 microRNA 214 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr13:77,121,645...77,121,752
Ensembl chr13:77,121,643...77,121,752 		JBrowse link
G Mir216a microRNA 216a ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr14:106,725,077...106,725,182
Ensembl chr14:106,725,077...106,725,182 		JBrowse link
G Mir216b microRNA 216b ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr14:106,714,026...106,714,127
Ensembl chr14:106,714,026...106,714,127 		JBrowse link
G Mir217 microRNA 217 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr14:106,732,485...106,732,589
Ensembl chr14:106,732,485...106,732,589 		JBrowse link
G Mir22 microRNA 22 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr10:60,805,331...60,805,425
Ensembl chr10:60,805,331...60,805,425 		JBrowse link
G Mir27a microRNA 27a ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr19:40,859,603...40,859,689 JBrowse link
G Mir27b microRNA 27b ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr17:1,819,147...1,819,243 JBrowse link
G Mir29a microRNA 29a ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr 4:60,617,955...60,618,042 JBrowse link
G Mir30a microRNA 30a ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr 9:33,233,941...33,234,011
Ensembl chr 9:33,233,941...33,234,011 		JBrowse link
G Mir30b microRNA 30b ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr 7:102,021,543...102,021,629 JBrowse link
G Mir31 microRNA 31 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr 5:108,714,849...108,714,954 JBrowse link
G Mir361 microRNA 361 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr  X:82,438,463...82,438,532 JBrowse link
G Mir375 microRNA 375 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr 9:83,906,582...83,906,656 JBrowse link
G Mir429 microRNA 429 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr 5:171,929,682...171,929,766 JBrowse link
G Mir532 microRNA 532 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27840954 NCBI chr  X:17,919,185...17,919,263
Ensembl chr  X:17,919,185...17,919,263 		JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16440434 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Mt-atp8 mitochondrially encoded ATP synthase membrane subunit 8 susceptibility ISO DNA:transversion: :m.7778G>T (mouse) RGD PMID:19759059 RGD:5490297 NCBI chr MT:7,758...7,961
Ensembl chr MT:7,743...7,946 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 IEP protein, mRNA:decreased expression:pancreas, blood cells RGD PMID:20442679 RGD:5131438 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:34,555,832...34,722,846 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:16822955 NCBI chr 1:190,643,866...190,645,901
Ensembl chr 1:190,643,867...190,645,901 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16127429 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Pdgfa platelet derived growth factor subunit A IEP associated with Reperfusion Injury;protein:increased expression:blood vessel RGD PMID:16601314 RGD:2292161 NCBI chr12:20,759,366...20,780,337
Ensembl chr12:20,754,208...20,780,322 		JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO protein: increased expression: serum RGD PMID:21750433 RGD:6483007 NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:113,420,710...113,438,343 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma IMP RGD PMID:18583255 RGD:2301875 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:22952646 NCBI chr 2:227,839,058...228,113,560
Ensembl chr 2:227,839,062...228,113,554 		JBrowse link
G Prss1 serine protease 1 susceptibility ISO
IEP 		protein:mutation: :p.R117H (human)
ClinVar Annotator: match by term: Recurrent pancreatitis
CTD Direct Evidence: marker/mechanism
protein:increased expression:cytosol 		ClinVar
CTD
RGD		 PMID:10381903 PMID:11260229 PMID:15017610 PMID:16036133 PMID:16505482 More... RGD:1599960, RGD:1599965 NCBI chr 4:71,331,249...71,334,452
Ensembl chr 4:71,331,246...71,334,452 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 onset ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19820421 PMID:21372163 RGD:5508226 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Rhob ras homolog family member B ISO ClinVar Annotator: match by term: Recurrent pancreatitis ClinVar PMID:25741868 PMID:32989326 NCBI chr 6:37,083,030...37,085,204
Ensembl chr 6:37,075,015...37,112,772 		JBrowse link
G RT1-Ba RT1 class II, locus Ba ISO CTD Direct Evidence: marker/mechanism CTD PMID:25217962 NCBI chr20:4,577,057...4,581,650
Ensembl chr20:4,576,843...4,581,653 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25217962 NCBI chr20:4,550,594...4,560,182
Ensembl chr20:4,550,596...4,560,165 		JBrowse link
G Sell selectin L IEP RGD PMID:16214426 RGD:5685705 NCBI chr13:78,950,100...78,969,604
Ensembl chr13:78,950,015...78,969,600 		JBrowse link
G Serpina1 serpin family A member 1 IEP RGD PMID:12770935 RGD:1641805 NCBI chr 6:128,631,101...128,653,125
Ensembl chr 6:128,619,382...128,660,703 		JBrowse link
G Serping1 serpin family G member 1 treatment ISO RGD PMID:9176084 RGD:8661649 NCBI chr 3:90,249,410...90,259,299
Ensembl chr 3:90,249,423...90,258,717 		JBrowse link
G Smo smoothened, frizzled class receptor IEP protein:increased expression:pancreas RGD PMID:20062892 RGD:2324983 NCBI chr 4:59,311,084...59,341,280
Ensembl chr 4:59,311,041...59,341,281 		JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Pancreatitis 		CTD
ClinVar		 PMID:10691414 PMID:10835640 PMID:11950815 PMID:12011155 PMID:12187509 More... NCBI chr18:36,121,626...36,133,596
Ensembl chr18:36,076,399...36,133,545 		JBrowse link
G Srf serum response factor ISO RGD PMID:16894357 RGD:1581427 NCBI chr 9:21,924,050...21,933,338
Ensembl chr 9:21,924,076...21,933,337 		JBrowse link
G Sst somatostatin ISO CTD Direct Evidence: therapeutic CTD PMID:7911442 NCBI chr11:90,461,546...90,462,823
Ensembl chr11:90,461,546...90,462,823 		JBrowse link
G Tac1 tachykinin, precursor 1 ISO mRNA:increased expression:lung, pancreas RGD PMID:16369913 RGD:5147636 NCBI chr 4:36,645,344...36,653,548
Ensembl chr 4:36,645,571...36,653,546 		JBrowse link
G Tacr1 tachykinin receptor 1 IMP
ISO 		mRNA, protein:increased expression:lung, pancreas RGD PMID:18580444 PMID:16369913 RGD:2304266, RGD:5147636 NCBI chr 4:116,478,617...116,647,492
Ensembl chr 4:116,478,617...116,647,492 		JBrowse link
G Tlr2 toll-like receptor 2 IEP RGD PMID:19260515 RGD:2312507 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194 		JBrowse link
G Tlr3 toll-like receptor 3 IEP protein:increased expression:spinal cord dorsal horn (rat) RGD PMID:21342497 RGD:5128695 NCBI chr16:53,554,916...53,572,321
Ensembl chr16:53,555,131...53,568,385 		JBrowse link
G Tlr4 toll-like receptor 4 ISO
IEP 		RGD PMID:19201771 PMID:19260515 RGD:4144143, RGD:2312507 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Tmem67 transmembrane protein 67 ISO ClinVar Annotator: match by term: Pancreatitis ClinVar PMID:19466712 PMID:19508969 PMID:19540516 PMID:19574260 PMID:20607301 More... NCBI chr 5:30,333,793...30,386,702
Ensembl chr 5:30,333,793...30,386,666 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17698068 NCBI chr10:58,349,936...58,375,021
Ensembl chr10:58,340,223...58,375,021 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO protein:increased expression:serum RGD PMID:12923961 RGD:2325163 NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801 		JBrowse link
G Xdh xanthine dehydrogenase IEP RGD PMID:14728722 RGD:7247701 NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:27,282,057...27,344,350 		JBrowse link
Acute Experimental Pancreatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 treatment IEP RGD PMID:18416460 RGD:13782074 NCBI chr12:39,733,519...39,782,942
Ensembl chr12:39,733,458...39,782,934 		JBrowse link
G Bcl2l1 Bcl2-like 1 IEP protein:increased expression:pancreas, mitochondrion (rat) RGD PMID:19331832 RGD:11353791 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Becn1 beclin 1 treatment ISO RGD PMID:22850625 RGD:11560530 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A IEP RGD PMID:10451498 RGD:10043817 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Ednra endothelin receptor type A treatment IMP RGD PMID:12799311 RGD:1581841 NCBI chr19:47,137,360...47,207,961
Ensembl chr19:47,137,771...47,201,284 		JBrowse link
G Fas Fas cell surface death receptor severity ISO protein:increased expression:Kupffer cell: RGD PMID:15797225 PMID:15797225 RGD:14700708, RGD:14700708 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104 		JBrowse link
G Faslg Fas ligand severity ISO protein:increased expression:Kupffer cell: RGD PMID:15797225 PMID:15797225 RGD:14700708, RGD:14700708 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503 		JBrowse link
G Gss glutathione synthetase IEP RGD PMID:17897920 RGD:11353819 NCBI chr 3:164,508,005...164,538,343
Ensembl chr 3:164,508,005...164,538,306 		JBrowse link
G Hmgb1 high mobility group box 1 treatment IMP RGD PMID:23706497 RGD:10402063 NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 IEP protein:increased expression:neutrophil: RGD PMID:26464680 RGD:11354914 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790 		JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment IEP
IMP 		RGD PMID:23706497 PMID:10201790 RGD:10402063, RGD:11520782 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Il10 interleukin 10 treatment IEP protein:increased expression:serum RGD PMID:19399939 PMID:25323753 RGD:2306925, RGD:11049477 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il4 interleukin 4 treatment IEP RGD PMID:24876883 RGD:10402805 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Jak1 Janus kinase 1 treatment IEP RGD PMID:21369693 RGD:19165136 NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:120,896,046...120,996,758 		JBrowse link
G Kmo kynurenine 3-monooxygenase disease_progression ISO
IMP 		RGD PMID:26752518 PMID:28398044 RGD:11342439, RGD:13703053 NCBI chr13:90,089,340...90,121,108
Ensembl chr13:90,089,463...90,125,151 		JBrowse link
G Kras KRAS proto-oncogene, GTPase IEP RGD PMID:8913708 RGD:11062095 NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320 		JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 ISO protein:decreased expression:pancreas RGD PMID:22850625 RGD:11560530 NCBI chr  X:122,038,734...122,087,745
Ensembl chr  X:121,922,187...122,087,675 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha treatment ISO RGD PMID:22850625 RGD:11560530 NCBI chr 3:164,243,204...164,244,850
Ensembl chr 3:164,243,093...164,244,850 		JBrowse link
G Mdm2 MDM2 proto-oncogene IEP protein:increased expression:pancreas (rat) RGD PMID:19850968 RGD:2317361 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791 		JBrowse link
G Mir155 microRNA 155 treatment ISO RGD PMID:29937734 PMID:30497068 RGD:21403683, RGD:21408596 NCBI chr11:37,261,114...37,261,178
Ensembl chr11:37,261,114...37,261,178 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO RGD PMID:16127429 RGD:11075069 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:19680809 RGD:11100040 NCBI chr18:24,038,596...24,049,061
Ensembl chr18:24,038,597...24,048,964 		JBrowse link
G Procr protein C receptor treatment IEP
IDA 		protein:increased expression:blood RGD PMID:25688263 PMID:24749346 RGD:13515127, RGD:13515128 NCBI chr 3:164,714,727...164,718,994
Ensembl chr 3:164,711,636...164,718,989 		JBrowse link
G Ptafr platelet-activating factor receptor treatment IDA RGD PMID:21633536 RGD:9999225 NCBI chr 5:150,049,322...150,079,060
Ensembl chr 5:150,049,460...150,079,408 		JBrowse link
G Reg1a regenerating family member 1 alpha severity IEP
IMP 		mRNA:increased expression:pancreas (rat) RGD PMID:1985964 PMID:19129610 RGD:729900, RGD:9850139 NCBI chr 4:112,450,466...112,453,130
Ensembl chr 4:112,450,468...112,453,585 		JBrowse link
G Reg3b regenerating family member 3 beta IEP protein:increased expression:serum (rat) RGD PMID:11066135 RGD:9831384 NCBI chr 4:112,419,776...112,423,014
Ensembl chr 4:112,419,776...112,423,014 		JBrowse link
G Serpinc1 serpin family C member 1 treatment ISO RGD PMID:19546838 RGD:11035262 NCBI chr13:75,790,558...75,804,826
Ensembl chr13:75,790,546...75,817,643 		JBrowse link
G Serpinf1 serpin family F member 1 IEP RGD PMID:10360224 RGD:8661651 NCBI chr10:60,748,504...60,760,898
Ensembl chr10:60,748,506...60,760,898 		JBrowse link
G Serping1 serpin family G member 1 IEP protein:decreased expression:plasma RGD PMID:10360224 RGD:8661651 NCBI chr 3:90,249,410...90,259,299
Ensembl chr 3:90,249,423...90,258,717 		JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 treatment IDA RGD PMID:15765407 RGD:10043090 NCBI chr18:36,121,626...36,133,596
Ensembl chr18:36,076,399...36,133,545 		JBrowse link
G Tnf tumor necrosis factor IEP associated with Anemia, Hemolytic RGD PMID:12845374 PMID:15164724 RGD:10449461, RGD:1580295 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A IEP protein:increased expression:serum RGD PMID:15164724 RGD:1580295 NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:159,837,032...159,849,816 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B IEP protein:increased expression:serum RGD PMID:15164724 RGD:1580295 NCBI chr 5:162,356,250...162,387,411
Ensembl chr 5:162,353,848...162,387,411 		JBrowse link
G Vwf von Willebrand factor IEP protein:increased expression:plasma: RGD PMID:17708840 RGD:11079229 NCBI chr 4:160,042,900...160,177,757
Ensembl chr 4:160,047,982...160,177,757 		JBrowse link
acute necrotizing pancreatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcyap1 adenylate cyclase activating polypeptide 1 IDA RGD PMID:15702783 RGD:2325308 NCBI chr 9:120,550,236...120,569,096
Ensembl chr 9:120,550,328...120,556,383 		JBrowse link
G Arg1 arginase 1 IDA RGD PMID:20697209 RGD:4142795 NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713 		JBrowse link
G Becn1 beclin 1 IEP protein:increased expression:pancreas RGD PMID:21926933 RGD:6483068 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 IEP mRNA:increased expression:pancreas RGD PMID:12604914 RGD:2293139 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 IEP mRNA:increased expression:liver, kidney, pancreas RGD PMID:9712737 RGD:2289078 NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690 		JBrowse link
G C5 complement C5 ISO RGD PMID:11292607 RGD:5130168 NCBI chr 3:38,668,174...38,759,468
Ensembl chr 3:38,668,174...38,759,468 		JBrowse link
G C5ar1 complement C5a receptor 1 ISO RGD PMID:11292607 RGD:5130168 NCBI chr 1:86,077,309...86,088,001 JBrowse link
G Calca calcitonin-related polypeptide alpha resistance IDA RGD PMID:19684430 RGD:5684345 NCBI chr 1:178,312,636...178,317,588
Ensembl chr 1:178,312,638...178,317,529 		JBrowse link
G Casp3 caspase 3 IEP RGD PMID:18288275 RGD:2293324 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 severity
treatment 		IEP
IDA 		mRNA:increased expression:pancreas RGD PMID:18642776 PMID:19050604 RGD:2307010, RGD:11062108 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Cd46 CD46 molecule severity IEP RGD PMID:16425382 RGD:1600479 NCBI chr13:109,104,122...109,134,903 JBrowse link
G Cd59b CD59b molecule severity IEP protein:decreased expression:pancreas, acinar cell RGD PMID:16425382 RGD:1600479 NCBI chr 3:110,914,008...110,932,489
Ensembl chr 3:110,914,091...110,935,310 		JBrowse link
G Ctsb cathepsin B IEP protein:increased activity:pancreas (rat) RGD PMID:17723883 RGD:2315517 NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 IEP mRNA:increased expression:pancreatic acinar cell RGD PMID:19818401 RGD:5135004 NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 severity IEP RGD PMID:18642776 RGD:2307010 NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255 		JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP protein:increased expression:pancreas, lung (rat) RGD PMID:20950211 RGD:4145335 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Il17a interleukin 17A IEP protein:increased expression:pancreas, serum (rat) RGD PMID:22990529 RGD:9068935 NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331 		JBrowse link
G Il1b interleukin 1 beta IEP mRNA:increased expression:peritoneal macrophages (rat) RGD PMID:22964727 RGD:7204517 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO rat model treated with human protein RGD PMID:7736749 RGD:8551826 NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:27,509,798...27,525,732 		JBrowse link
G Il6 interleukin 6 treatment IDA
IEP 		protein:increased expression:plasma (rat) RGD PMID:11780340 PMID:19050604 RGD:11062058, RGD:11062108 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Mif macrophage migration inhibitory factor IDA RGD PMID:12612911 RGD:727512 NCBI chr20:12,767,138...12,791,222
Ensembl chr 4:134,041,774...134,042,121
Ensembl chr20:134,041,774...134,042,121 		JBrowse link
G Mmp2 matrix metallopeptidase 2 IEP mRNA:increased expression:pancreas (rat) RGD PMID:11590325 RGD:7207204 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856 		JBrowse link
G Nfkbia NFKB inhibitor alpha treatment IEP RGD PMID:19174608 RGD:10414072 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Nos1 nitric oxide synthase 1 treatment IDA RGD PMID:23300603 RGD:7257665 NCBI chr12:44,276,011...44,456,371
Ensembl chr12:44,287,614...44,371,837 		JBrowse link
G Nos2 nitric oxide synthase 2 IEP protein:increased enzyme activity:pancreas RGD PMID:15257108 RGD:2325241 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 IEP protein:increased expression:epithelial cell of pancreas (rat) RGD PMID:12210084 RGD:2311232 NCBI chr12:12,793,957...12,799,156
Ensembl chr12:12,793,957...12,799,156 		JBrowse link
G Pthlh parathyroid hormone-like hormone ISO CTD Direct Evidence: marker/mechanism CTD PMID:25035110 NCBI chr 4:181,919,400...181,930,454
Ensembl chr 4:181,919,400...181,930,454 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IEP protein:increased expression:pancreas RGD PMID:18241655 RGD:2298789 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Selp selectin P IMP RGD PMID:19451746 RGD:2312307 NCBI chr13:79,009,379...79,044,994
Ensembl chr13:79,009,475...79,044,987 		JBrowse link
G Serpine1 serpin family E member 1 disease_progression IEP
ISO 		protein:increased expression:plasma (rat) RGD PMID:17446839 PMID:15257107 RGD:8547894, RGD:13208542 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357 		JBrowse link
G Serpinf2 serpin family F member 2 IDA protein:increased expression:plasma RGD PMID:10423332 RGD:1625538 NCBI chr10:60,770,698...60,778,782
Ensembl chr10:60,770,698...60,778,996 		JBrowse link
G Tacr1 tachykinin receptor 1 IEP mRNA,protein:increased expression:lung RGD PMID:12857498 RGD:5147821 NCBI chr 4:116,478,617...116,647,492
Ensembl chr 4:116,478,617...116,647,492 		JBrowse link
G Tbxas1 thromboxane A synthase 1 IDA RGD PMID:9700944 RGD:1601470 NCBI chr 4:68,631,841...68,803,959
Ensembl chr 4:68,631,838...68,803,969 		JBrowse link
G Tlr2 toll-like receptor 2 IEP mRNA:increased expression:liver RGD PMID:16524509 RGD:2312724 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194 		JBrowse link
G Tlr4 toll-like receptor 4 IEP mRNA:increased expression:liver RGD PMID:16524509 RGD:2312724 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Tlr9 toll-like receptor 9 IEP mRNA, protein:increased expression:pancreas (rat) RGD PMID:18376319 RGD:5130184 NCBI chr 8:115,743,407...115,747,523
Ensembl chr 8:115,742,889...115,750,148 		JBrowse link
acute pancreatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arf1 ARF GTPase 1 treatment ISO RGD PMID:22570480 RGD:9684857 NCBI chr10:44,497,543...44,513,994 JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 IEP mRNA,protein:increased expression:pancreas RGD PMID:19726343 RGD:9586043 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155 		JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger ISO protein:increased expression:pancreatic acinar cell: RGD PMID:19585519 RGD:9491843 NCBI chr17:86,240,683...86,250,044
Ensembl chr17:86,243,491...86,250,024 		JBrowse link
G Cck cholecystokinin disease_progression ISO protein:decreased expression:blood plasma (human) RGD PMID:11185710 RGD:407419866 NCBI chr 8:130,031,012...130,037,702
Ensembl chr 8:130,031,013...130,037,686 		JBrowse link
G Cd163 CD163 molecule ISO associated with liver disease;protein:increased expression:blood serum (human) RGD PMID:26339412 RGD:11251207 NCBI chr 4:158,770,751...158,804,146
Ensembl chr 4:158,770,749...158,804,146 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 treatment IMP RGD PMID:22213034 RGD:9491790 NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,233,329...10,242,999 		JBrowse link
G F3 coagulation factor III, tissue factor ISO protein:increased expression:serum (human, mouse) RGD PMID:27923687 RGD:14398732 NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369 		JBrowse link
G F7 coagulation factor VII treatment ISO human protein in a rat model RGD PMID:17506000 RGD:11049543 NCBI chr16:83,191,896...83,202,775
Ensembl chr16:83,191,914...83,202,738 		JBrowse link
G Il10 interleukin 10 no_association ISO DNA:SNP:promoter:-1082G>A (human)
DNA:SNP:promoter: -819T>C (human) 		RGD PMID:27173345 PMID:27173345 RGD:14975140, RGD:14975140 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Irf9 interferon regulatory factor 9 IEP mRNA,protein:increased expression:kidney RGD PMID:32462510 RGD:125093744 NCBI chr15:33,065,422...33,071,881
Ensembl chr15:33,065,659...33,071,879 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase IEP mRNA,protein:decreased expression:jejunum RGD PMID:23599644 RGD:12910752 NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,903,033...32,978,812 		JBrowse link
G Lep leptin IEP associated with fatty liver disease; protein:increased expression:serum: RGD PMID:26634430 RGD:11552763 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661 		JBrowse link
G Mir155 microRNA 155 severity ISO RGD PMID:29937734 PMID:30497068 RGD:21403683, RGD:21408596 NCBI chr11:37,261,114...37,261,178
Ensembl chr11:37,261,114...37,261,178 		JBrowse link
G Mtnr1b melatonin receptor 1B IMP RGD PMID:12510864 RGD:9588676 NCBI chr 8:20,919,593...20,934,109
Ensembl chr 8:20,919,593...20,934,109 		JBrowse link
G Reg3a regenerating islet-derived 3 alpha severity IMP RGD PMID:19129610 RGD:9850139 NCBI chr 4:112,430,397...112,433,163
Ensembl chr 4:112,430,424...112,433,163 		JBrowse link
G Reg3b regenerating family member 3 beta severity IMP RGD PMID:18437087 RGD:9831433 NCBI chr 4:112,419,776...112,423,014
Ensembl chr 4:112,419,776...112,423,014 		JBrowse link
G Serpina1 serpin family A member 1 IEP
ISO 		associated with fatty liver disease; protein:decreased expression:serum: RGD PMID:26634430 PMID:26634430 RGD:11552763, RGD:11552763 NCBI chr 6:128,631,101...128,653,125
Ensembl chr 6:128,619,382...128,660,703 		JBrowse link
G Tlr4 toll-like receptor 4 ISO mRNA,protein:increased expression:liver: RGD PMID:18436016 RGD:14697701 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 severity
ameliorates 		ISO
IDA 		RGD PMID:26250893 PMID:19787284 RGD:11522077, RGD:127284839 NCBI chr 9:20,259,227...20,276,879
Ensembl chr 9:20,261,408...20,276,892 		JBrowse link
alcoholic pancreatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car2 carbonic anhydrase 2 ISO RGD PMID:15831920 RGD:408425973 NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064 		JBrowse link
G Cck cholecystokinin disease_progression ISO protein:decreased expression:blood plasma (human) RGD PMID:11185710 RGD:407419866 NCBI chr 8:130,031,012...130,037,702
Ensembl chr 8:130,031,013...130,037,686 		JBrowse link
G Cftr CF transmembrane conductance regulator ISO DNA:missense mutations: :p.L1156F, Q1352H (human) RGD PMID:26089335 RGD:11566036 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643 		JBrowse link
G Pthlh parathyroid hormone-like hormone ISO CTD Direct Evidence: marker/mechanism CTD PMID:22280800 NCBI chr 4:181,919,400...181,930,454
Ensembl chr 4:181,919,400...181,930,454 		JBrowse link
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C ISO DNA:polymorphisms: :p.N129K, p.R131K, p.W208R (human) RGD PMID:12806614 RGD:2317503 NCBI chr 9:96,187,382...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
autoimmune pancreatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car2 carbonic anhydrase 2 ISO RGD PMID:15831920 RGD:408425973 NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064 		JBrowse link
G RT1-Bb RT1 class II, locus Bb severity ISO DNA:polymorphisms, haplotype:cds:HLA-DQB1*0302 (human) RGD PMID:18155707 RGD:5147621 NCBI chr20:4,598,475...4,604,118
Ensembl chr20:4,598,475...4,604,118 		JBrowse link
Calcific Pancreatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Reg1a regenerating family member 1 alpha ISO protein:decreased expression:pancreatic juice (human) RGD PMID:3147713 RGD:9850117 NCBI chr 4:112,450,466...112,453,130
Ensembl chr 4:112,450,468...112,453,585 		JBrowse link
Chronic Experimental Pancreatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase IEP protein:increased expression:arcuate nucleus (rat) RGD PMID:27778022 RGD:38456012 NCBI chr20:9,709,394...9,733,925
Ensembl chr20:9,709,395...9,734,066 		JBrowse link
G Gli1 GLI family zinc finger 1 IEP RGD PMID:24782623 RGD:12879405 NCBI chr 7:65,042,237...65,054,888
Ensembl chr 7:65,042,237...65,054,540 		JBrowse link
G Il1b interleukin 1 beta ISO RGD PMID:22173919 RGD:10044253 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IEP RGD PMID:22359633 RGD:11035224 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260 		JBrowse link
G Ptch1 patched 1 IEP RGD PMID:24782623 RGD:12879405 NCBI chr17:1,548,449...1,613,461
Ensembl chr17:1,548,449...1,613,461 		JBrowse link
G Smo smoothened, frizzled class receptor IEP RGD PMID:24782623 RGD:12879405 NCBI chr 4:59,311,084...59,341,280
Ensembl chr 4:59,311,041...59,341,281 		JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 treatment IDA
IEP 		protein:increased secretion:pancreatic juice: RGD PMID:19904222 PMID:12123090 PMID:22173919 RGD:10043091, RGD:10044261, RGD:10044253 NCBI chr18:36,121,626...36,133,596
Ensembl chr18:36,076,399...36,133,545 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 IEP RGD PMID:26645248 RGD:14995470 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
Chronic Pancreatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor ISO protein:decreased expression:serum RGD PMID:31870801 RGD:597621670 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,151,965...4,155,685 		JBrowse link
G Apoa4 apolipoprotein A4 ISO protein:decreased expression:blood plasma (human) RGD PMID:11555832 RGD:5685680 NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:55,434,168...55,438,164 		JBrowse link
G Bad BCL2-associated agonist of cell death severity IEP RGD PMID:22549003 RGD:10053701 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034 		JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger ISO protein:increased expression:pancreatic acinar cell:
protein:increased expression:exocrine pancreas: 		RGD PMID:19585519 PMID:19585519 RGD:9491843, RGD:9491843 NCBI chr17:86,240,683...86,250,044
Ensembl chr17:86,243,491...86,250,024 		JBrowse link
G Ca1 carbonic anhydrase 1 ISO RGD PMID:12806141 RGD:408425977 NCBI chr 2:88,550,681...88,593,454
Ensembl chr 2:88,495,475...88,593,454 		JBrowse link
G Car2 carbonic anhydrase 2 ISO RGD PMID:12806141 RGD:408425977 NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064 		JBrowse link
G Cel carboxyl ester lipase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25774637 NCBI chr 3:32,281,518...32,289,019
Ensembl chr 3:32,281,518...32,289,019 		JBrowse link
G Cftr CF transmembrane conductance regulator ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Chronic pancreatitis 		CTD
ClinVar		 PMID:10746558 PMID:15536480 PMID:16189704 PMID:16193325 PMID:16244288 More... NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643 		JBrowse link
G Col1a1 collagen type I alpha 1 chain treatment IDA RGD PMID:21926544 RGD:8552779 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460 		JBrowse link
G Cpa1 carboxypeptidase A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23955596 NCBI chr 4:60,224,801...60,230,928
Ensembl chr 4:60,224,801...60,230,928 		JBrowse link
G Ctrc chymotrypsin C ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Chronic pancreatitis | ClinVar Annotator: match by term: Pancreatitis, chronic, susceptibility to 		CTD
ClinVar		 PMID:18059268 PMID:18172691 PMID:19453252 PMID:20625975 PMID:22427236 More... NCBI chr 5:159,430,333...159,439,557
Ensembl chr 5:159,430,335...159,439,545 		JBrowse link
G Cygb cytoglobin IEP RGD PMID:14647402 RGD:9685173 NCBI chr10:102,376,506...102,386,272
Ensembl chr10:102,376,507...102,386,272 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 ISO mRNA,protein:increased expression:pancreas RGD PMID:17114010 RGD:6482236 NCBI chr 1:64,985,161...64,993,274
Ensembl chr 1:64,985,161...64,993,276 		JBrowse link
G Ifng interferon gamma disease_progression IEP RGD PMID:11345142 RGD:10755767 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 ISO mRNA,protein:increased expression:pancreas RGD PMID:17114010 RGD:6482236 NCBI chr 3:144,859,453...144,894,883
Ensembl chr 3:144,859,453...144,894,872 		JBrowse link
G Ngf nerve growth factor IEP protein:increased expression:pancreas RGD PMID:16098667 RGD:5144071 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834 		JBrowse link
G Ngfr nerve growth factor receptor ISO mRNA:increased expression:pancreas (human) RGD PMID:12741461 RGD:5508378 NCBI chr10:81,012,077...81,030,305
Ensembl chr10:81,012,089...81,030,305 		JBrowse link
G Prss1 serine protease 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18206817 NCBI chr 4:71,331,249...71,334,452
Ensembl chr 4:71,331,246...71,334,452 		JBrowse link
G Pthlh parathyroid hormone-like hormone ISO CTD Direct Evidence: marker/mechanism CTD PMID:25035110 NCBI chr 4:181,919,400...181,930,454
Ensembl chr 4:181,919,400...181,930,454 		JBrowse link
G Reg1a regenerating family member 1 alpha IEP protein:increased expression:pancreas, acinar cell, zymogen granule (rat) RGD PMID:12764608 RGD:9831428 NCBI chr 4:112,450,466...112,453,130
Ensembl chr 4:112,450,468...112,453,585 		JBrowse link
G Reg3b regenerating family member 3 beta treatment IDA
IEP 		protein:increased expression:pancreas, acinar cell, zymogen granule (rat) RGD PMID:10505754 PMID:12764608 RGD:9831401, RGD:9831428 NCBI chr 4:112,419,776...112,423,014
Ensembl chr 4:112,419,776...112,423,014 		JBrowse link
G Rnf2 ring finger protein 2 ISO protein:increased expression:pancreas RGD PMID:19585519 RGD:9491843 NCBI chr13:66,103,943...66,136,038
Ensembl chr13:66,083,653...66,133,161 		JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 ISO ClinVar Annotator: match by term: Chronic pancreatitis | ClinVar Annotator: match by term: Pancreatitis, chronic, susceptibility to
CTD Direct Evidence: marker/mechanism 		ClinVar
CTD
RGD		 PMID:10691414 PMID:10835640 PMID:11950815 PMID:12011155 PMID:12187509 More... RGD:1599102 NCBI chr18:36,121,626...36,133,596
Ensembl chr18:36,076,399...36,133,545 		JBrowse link
Experimental Pancreatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Elane elastase, neutrophil expressed treatment IMP RGD PMID:18486906 RGD:10450567 NCBI chr 7:10,467,877...10,469,725
Ensembl chr 7:10,467,877...10,469,725 		JBrowse link
G Fgf21 fibroblast growth factor 21 treatment ISO RGD PMID:19664632 PMID:19664632 RGD:10401870, RGD:10401870 NCBI chr 1:105,219,825...105,221,376
Ensembl chr 1:105,219,825...105,232,056 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma treatment IDA RGD PMID:19195057 RGD:12791282 NCBI chr  X:157,358,279...157,397,563
Ensembl chr  X:157,367,639...157,392,757 		JBrowse link
G Reg3b regenerating family member 3 beta IEP protein:increased expression:pancreatic juice (rat) RGD PMID:7809015 RGD:9999210 NCBI chr 4:112,419,776...112,423,014
Ensembl chr 4:112,419,776...112,423,014 		JBrowse link
G Tbxa2r thromboxane A2 receptor treatment IMP RGD PMID:11341608 RGD:11059600 NCBI chr 7:9,034,077...9,041,489
Ensembl chr 7:9,034,108...9,038,905 		JBrowse link
Hereditary Pancreatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agmat agmatinase ISO ClinVar Annotator: match by term: Hereditary pancreatitis ClinVar PMID:23721890 PMID:28492532 NCBI chr 5:159,326,680...159,357,300
Ensembl chr 5:159,343,160...159,357,299 		JBrowse link
G Casp9 caspase 9 ISO ClinVar Annotator: match by term: Hereditary pancreatitis ClinVar PMID:23721890 PMID:28492532 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cela2a chymotrypsin like elastase 2A ISO ClinVar Annotator: match by term: Hereditary pancreatitis ClinVar PMID:23721890 PMID:28492532 NCBI chr 5:159,409,900...159,420,282
Ensembl chr 5:159,409,899...159,426,208 		JBrowse link
G Cftr CF transmembrane conductance regulator ISO ClinVar Annotator: match by term: Hereditary chronic pancreatitis | ClinVar Annotator: match by term: Hereditary pancreatitis
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hereditary chronic pancreatitis | ClinVar Annotator: match by term: Hereditary pancreatitis | ClinVar Annotator: match by term: Pancreatitis, idiopathic, susceptibility to 		OMIM
ClinVar
CTD		 PMID:754013 PMID:1282016 PMID:1283148 PMID:1283149 PMID:1283151 More... NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643 		JBrowse link
G Clec5a C-type lectin domain containing 5A ISO ClinVar Annotator: match by term: Hereditary pancreatitis ClinVar PMID:25741868 NCBI chr 4:70,373,855...70,383,560
Ensembl chr 4:70,374,529...70,398,230 		JBrowse link
G Cpa1 carboxypeptidase A1 ISO ClinVar Annotator: match by term: Hereditary chronic pancreatitis | ClinVar Annotator: match by term: Hereditary pancreatitis ClinVar PMID:9536098 PMID:16199547 PMID:17576681 PMID:23955596 PMID:24522117 More... NCBI chr 4:60,224,801...60,230,928
Ensembl chr 4:60,224,801...60,230,928 		JBrowse link
G Ctrc chymotrypsin C susceptibility ISO ClinVar Annotator: match by term: Hereditary chronic pancreatitis | ClinVar Annotator: match by term: Hereditary pancreatitis
CTD Direct Evidence: marker/mechanism 		ClinVar
OMIM
CTD		 PMID:190101 PMID:5256061 PMID:8168476 PMID:9536098 PMID:16199547 More... NCBI chr 5:159,430,333...159,439,557
Ensembl chr 5:159,430,335...159,439,545 		JBrowse link
G Ddi2 DNA damage inducible 1 homolog 2 ISO ClinVar Annotator: match by term: Hereditary pancreatitis ClinVar PMID:23721890 PMID:28492532 NCBI chr 5:159,272,625...159,318,365
Ensembl chr 5:159,272,625...159,318,310 		JBrowse link
G Dnajc16 DnaJ heat shock protein family (Hsp40) member C16 ISO ClinVar Annotator: match by term: Hereditary pancreatitis ClinVar PMID:23721890 PMID:28492532 NCBI chr 5:159,355,279...159,389,267
Ensembl chr 5:159,361,314...159,389,298 		JBrowse link
G Ephb6 Eph receptor B6 ISO ClinVar Annotator: match by term: Hereditary pancreatitis ClinVar PMID:25741868 NCBI chr 4:71,458,632...71,473,889
Ensembl chr 4:71,458,971...71,476,659 		JBrowse link
G Mgam maltase-glucoamylase ISO ClinVar Annotator: match by term: Hereditary pancreatitis ClinVar PMID:25741868 NCBI chr 4:70,408,263...70,568,752
Ensembl chr 4:70,408,263...70,568,752 		JBrowse link
G Or9a4 olfactory receptor family 9 subfamily A member 4 ISO ClinVar Annotator: match by term: Hereditary pancreatitis ClinVar PMID:25741868 NCBI chr 4:70,368,300...70,369,244
Ensembl chr 4:70,368,300...70,369,244 		JBrowse link
G Plekhm2 pleckstrin homology and RUN domain containing M2 ISO ClinVar Annotator: match by term: Hereditary pancreatitis ClinVar PMID:23721890 PMID:28492532 NCBI chr 5:159,222,620...159,261,666
Ensembl chr 5:159,223,300...159,261,642 		JBrowse link
G Prss1 serine protease 1 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hereditary pancreatitis
ClinVar Annotator: match by term: Hereditary chronic pancreatitis | ClinVar Annotator: match by term: Hereditary pancreatitis
ClinVar Annotator: match by term: Hereditary chronic pancreatitis | ClinVar Annotator: match by term: Hereditary pancreatitis | ClinVar Annotator: match by term: Pancreatitis, chronic, protection against 		OMIM
CTD
ClinVar		 PMID:2539344 PMID:6023921 PMID:8841182 PMID:9322498 PMID:9536098 More... NCBI chr 4:71,331,249...71,334,452
Ensembl chr 4:71,331,246...71,334,452 		JBrowse link
G Prss37 serine protease 37 ISO ClinVar Annotator: match by term: Hereditary pancreatitis ClinVar PMID:25741868 NCBI chr 4:70,289,678...70,301,259
Ensembl chr 4:70,289,678...70,302,122 		JBrowse link
G Prss58 serine protease 58 ISO ClinVar Annotator: match by term: Hereditary pancreatitis ClinVar PMID:25741868 NCBI chr 4:70,719,326...70,731,158
Ensembl chr 4:70,719,326...70,723,647 		JBrowse link
G Sar1b secretion associated, Ras related GTPase 1B ISO ClinVar Annotator: match by term: Hereditary pancreatitis ClinVar PMID:12692552 PMID:25741868 NCBI chr10:36,525,365...36,555,009
Ensembl chr10:36,519,384...36,555,005 		JBrowse link
G Slc25a34 solute carrier family 25, member 34 ISO ClinVar Annotator: match by term: Hereditary pancreatitis ClinVar PMID:23721890 PMID:28492532 NCBI chr 5:153,932,081...153,936,854
Ensembl chr 5:159,215,120...159,219,892 		JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hereditary chronic pancreatitis | ClinVar Annotator: match by term: Hereditary pancreatitis 		CTD
OMIM
ClinVar		 PMID:120111 PMID:1613792 PMID:1870127 PMID:3501289 PMID:9536098 More... NCBI chr18:36,121,626...36,133,596
Ensembl chr18:36,076,399...36,133,545 		JBrowse link
G Ssbp1 single stranded DNA binding protein 1 ISO ClinVar Annotator: match by term: Hereditary pancreatitis ClinVar PMID:25741868 NCBI chr 4:70,232,740...70,242,824
Ensembl chr 4:70,232,794...70,243,700 		JBrowse link
G Tas2r108 taste receptor, type 2, member 108 ISO ClinVar Annotator: match by term: Hereditary pancreatitis ClinVar PMID:25741868 NCBI chr 4:69,287,667...69,288,581
Ensembl chr 4:70,254,367...70,255,281 		JBrowse link
G Tas2r137 taste receptor, type 2, member 137 ISO ClinVar Annotator: match by term: Hereditary pancreatitis ClinVar PMID:25741868 NCBI chr 4:69,279,276...69,286,935
Ensembl chr 4:70,251,091...70,252,041 		JBrowse link
G Tas2r138 taste receptor, type 2, member 138 ISO ClinVar Annotator: match by term: Hereditary pancreatitis ClinVar PMID:25741868 NCBI chr 4:70,395,042...70,396,037 JBrowse link
G Trpv6 transient receptor potential cation channel, subfamily V, member 6 ISO ClinVar Annotator: match by term: Hereditary pancreatitis ClinVar PMID:25741868 NCBI chr 4:71,474,006...71,489,667
Ensembl chr 4:71,474,007...71,489,671 		JBrowse link
Tropical Calcific Pancreatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spink1 serine peptidase inhibitor, Kazal type 1 ISO CTD Direct Evidence: marker/mechanism CTD
OMIM		 NCBI chr18:36,121,626...36,133,596
Ensembl chr18:36,076,399...36,133,545 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19167
    disease of anatomical entity 18473
      endocrine system disease 7008
        pancreas disease 1250
          pancreatitis 222
            Chronic Pancreatitis + 52
            Experimental Pancreatitis + 45
            Graft Pancreatitis 0
            acute pancreatitis + 82
            alcoholic pancreatitis 5
paths to the root