RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
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CCL2
C-C motif chemokine ligand 2
treatment
ISO
RGD
PMID:8903512 PMID:17314328
RGD:8549743 , RGD:8549770
NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
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CCL3
C-C motif chemokine ligand 3
IEP ISO
associated with Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
RGD
PMID:18846416 PMID:17898087
RGD:7241813 , RGD:2307059
NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
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CD40
CD40 molecule
ISO
RGD
PMID:14569091
RGD:7248599
NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863
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CD40LG
CD40 ligand
treatment
ISO
RGD
PMID:14569091
RGD:7248599
NCBI chr X:136,648,158...136,660,390
Ensembl chr X:136,648,158...136,660,390
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CSF1R
colony stimulating factor 1 receptor
treatment
ISO
RGD
PMID:23408165
RGD:151665815
NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372
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FCGR2A
Fc gamma receptor IIa
ISO
DNA:CNV:3'UTR:
RGD
PMID:16482158
RGD:2293335
NCBI chr 1:161,505,457...161,524,048
Ensembl chr 1:161,505,430...161,524,013
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IL1B
interleukin 1 beta
ISO
RGD
PMID:19959716
RGD:7175502
NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
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IL1RN
interleukin 1 receptor antagonist
treatment
IDA
human protein in a rat model
RGD
PMID:7637259
RGD:8551712
NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016
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JUND
JunD proto-oncogene, AP-1 transcription factor subunit
ISO
RGD
PMID:18443593
RGD:2293336
NCBI chr19:18,279,694...18,281,622
Ensembl chr19:18,279,694...18,281,622
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MMP12
matrix metallopeptidase 12
ISO
RGD
PMID:20488952 PMID:12626598
RGD:2325762 , RGD:737630
NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982
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MMP3
matrix metallopeptidase 3
ISO
RGD
PMID:11095647
RGD:7241255
NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609
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MMP9
matrix metallopeptidase 9
ISO
protein:increased expression:renal cortex (rat)
RGD
PMID:16046515
RGD:2313720
NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
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MTOR
mechanistic target of rapamycin kinase
ISO
RGD
PMID:21403644
RGD:7245940
NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556
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STAT6
signal transducer and activator of transcription 6
ISO
RGD
PMID:21985369
RGD:7243976
NCBI chr12:57,095,408...57,111,362
Ensembl chr12:57,095,408...57,132,139
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TLR9
toll like receptor 9
severity
ISO
RGD
PMID:20847283
RGD:7246899
NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all