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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:endophthalmitis
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Accession:DOID:4692 term browser browse the term
Definition:A globe disease that is characterized by inflammation of the inside of the eye. (DO)
Synonyms:exact_synonym: Infectious Endophthalmitides;   Infectious Endophthalmitis;   Ophthalmia;   endophthalmitides;   ophthalmias
 primary_id: MESH:D009877
 xref: NCI:C34586
For additional species annotation, visit the Alliance of Genome Resources.


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endophthalmitis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fas Fas cell surface death receptor IEP protein:increased expression:retinal ganglion cell, bipolar cell of retina, photoreceptor (rat) RGD PMID:19039600 RGD:8662445 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Ifng interferon gamma IEP protein:increased expression:vitreous: RGD PMID:16544114 RGD:7829753 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il1b interleukin 1 beta IEP protein:increased expression:vitreous: RGD PMID:16544114 RGD:7829753 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Slpi secretory leukocyte peptidase inhibitor IEP associated with Staphylococcal Infections;protein:increased expression:cornea, retina, vitreous humor RGD PMID:18274645 RGD:9999421 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453 		JBrowse link
G Tlr2 toll-like receptor 2 ISO RGD PMID:19995266 PMID:22163046 RGD:8552880, RGD:8553060 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tnf tumor necrosis factor IEP protein:increased expression:vitreous: RGD PMID:16544114 RGD:7829753 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19050
    sensory system disease 7255
      eye disease 3731
        globe disease 16
          endophthalmitis 6
            gonococcal endophthalmia 0
            purulent endophthalmitis + 0
            suppurative uveitis + 0
Path 2
Term Annotations click to browse term
  disease 19050
    Pathological Conditions, Signs and Symptoms 13532
      Signs and Symptoms 11084
        Neurologic Manifestations 10336
          sensory system disease 7255
            eye disease 3731
              globe disease 16
                endophthalmitis 6
                  gonococcal endophthalmia 0
                  purulent endophthalmitis + 0
                  suppurative uveitis + 0
paths to the root