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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:freemartinism
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Accession:DOID:4671 term browser browse the term
Definition:A condition occurring in the female offspring of dizygotic twins (TWIN, DIZYGOTIC) in a mixed-sex pregnancy, usually in CATTLE. Freemartinism can occur in other mammals. When placental fusion between the male and the female FETUSES permits the exchange of fetal cells and fetal hormones, TESTICULAR HORMONES from the male fetus can androgenize the female fetus producing a sterile XX/XY chimeric 'female'(CHIMERISM).
Synonyms:primary_id: MESH:D005611
 xref: EFO:1000939
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Path 1
Term Annotations click to browse term
  disease 14338
    Animal Diseases 1263
      Cattle Diseases 2
        freemartinism 0
Path 2
Term Annotations click to browse term
  disease 14338
    Developmental Disease 12614
      Congenital, Hereditary, and Neonatal Diseases and Abnormalities 11878
        genetic disease 11608
          chromosomal disease 2918
            Sex Chromosome Disorders 77
              Sex Chromosome Disorders of Sex Development 24
                freemartinism 0
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