Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:hypokalemia
go back to main search page
Accession:DOID:4500 term browser browse the term
Definition:Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)
Synonyms:exact_synonym: hypokalemias;   hypopotassemia;   hypopotassemias;   potassium deficiency disorder
 primary_id: MESH:D007008
 xref: NCI:C34939
For additional species annotation, visit the Alliance of Genome Resources.


GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
hypokalemia term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:1848636 PMID:2826064 PMID:17292646 NCBI chrNW_004624774:8,211,723...8,215,962
Ensembl chrNW_004624774:8,211,984...8,213,240
JBrowse link
G Agt angiotensinogen ISO CTD Direct Evidence: therapeutic CTD PMID:7182184 NCBI chrNW_004624775:18,846,222...18,856,093
Ensembl chrNW_004624775:18,849,118...18,855,577
JBrowse link
G Atp12a ATPase H+/K+ transporting non-gastric alpha2 subunit ISO RGD PMID:9729517 RGD:13838663 NCBI chrNW_004624776:18,466,952...18,495,693
Ensembl chrNW_004624776:18,467,967...18,495,651
JBrowse link
G Cldn10 claudin 10 ISO ClinVar Annotator: match by term: Hypokalemia ClinVar PMID:25741868 NCBI chrNW_004624879:2,178,896...2,298,905
Ensembl chrNW_004624879:2,179,142...2,298,924
JBrowse link
G Ins insulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:496411 NCBI chrNW_004624767:14,999,088...15,000,035
Ensembl chrNW_004624767:14,999,088...15,000,035
JBrowse link
G Kcnj16 potassium inwardly rectifying channel subfamily J member 16 ISO protein:decreased expression:cortical collecting duct, distal convoluted tubule (rat) RGD PMID:28931751 RGD:38500204 NCBI chrNW_004624801:269,449...335,535
Ensembl chrNW_004624801:269,533...335,535
JBrowse link
G Nppb natriuretic peptide B ISO CTD Direct Evidence: marker/mechanism CTD PMID:20339970 NCBI chrNW_004624818:1,139,776...1,141,010 JBrowse link
G Nr3c1 nuclear receptor subfamily 3 group C member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11932321 NCBI chrNW_004624774:2,496,276...2,603,894
Ensembl chrNW_004624774:2,495,304...2,602,632
JBrowse link
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:323586 PMID:1327015 PMID:4323972 PMID:6254450 PMID:6258369 More... NCBI chrNW_004624738:7,442,223...7,448,513
Ensembl chrNW_004624738:7,442,292...7,445,020
JBrowse link
G Rhcg Rh family C glycoprotein ISO protein:increased expression:outer medulla of kidney RGD PMID:21753075 RGD:9850155 NCBI chrNW_004624768:16,623,667...16,644,149
Ensembl chrNW_004624768:16,623,599...16,644,189
JBrowse link
G Slc12a3 solute carrier family 12 member 3 ISO ClinVar Annotator: match by term: Hypokalemia ClinVar PMID:8528245 PMID:9734597 PMID:10988270 PMID:12039972 PMID:17329572 More... NCBI chrNW_004624746:29,087,867...29,132,793
Ensembl chrNW_004624746:29,098,254...29,132,752
JBrowse link
G Sst somatostatin ISO CTD Direct Evidence: therapeutic CTD PMID:2563217 NCBI chrNW_004624730:69,213,917...69,215,296
Ensembl chrNW_004624730:69,213,781...69,215,477
JBrowse link
Hypokalemic Tubulopathy and Deafness term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnj16 potassium inwardly rectifying channel subfamily J member 16 ISO ClinVar Annotator: match by term: Hypokalemic tubulopathy and deafness OMIM
ClinVar
PMID:33811157 NCBI chrNW_004624801:269,449...335,535
Ensembl chrNW_004624801:269,533...335,535
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14230
    Nutritional and Metabolic Diseases 6954
      disease of metabolism 6954
        mineral metabolism disease 899
          hypokalemia 12
            Familial Hypokalemia + 1
Path 2
Term Annotations click to browse term
  disease 14230
    Nutritional and Metabolic Diseases 6954
      disease of metabolism 6954
        acquired metabolic disease 2113
          mineral metabolism disease 899
            hypokalemia 12
              Familial Hypokalemia + 1
paths to the root