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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:lung adenocarcinoma
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Accession:DOID:3910 term browser browse the term
Definition:A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin. (DO)
Synonyms:exact_synonym: LUAD;   adenocarcinoma of lung;   bronchogenic lung adenocarcinoma;   non-small cell lung adenocarcinoma;   nonsmall cell adenocarcinoma;   pulmonary adenocarcinoma
 related_synonym: adenocarcinoma of lung, somatic
 primary_id: MESH:D000077192
 xref: EFO:0000571;   EFO:0005288;   GARD:5742;   NCI:C129299;   NCI:C27745;   NCI:C3512
For additional species annotation, visit the Alliance of Genome Resources.

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
lung adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abce1 ATP binding cassette subfamily E member 1 severity ISO mRNA, protein:increased expression:lung (human) RGD PMID:18788636 RGD:11046260 NCBI chrNW_004955428:1,029,909...1,058,902
Ensembl chrNW_004955428:1,029,399...1,058,902 		JBrowse link
G Acsl4 acyl-CoA synthetase long chain family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955490:6,143,833...6,228,395
Ensembl chrNW_004955490:6,143,833...6,228,452 		JBrowse link
G Adam19 ADAM metallopeptidase domain 19 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chrNW_004955408:11,651,298...11,746,391
Ensembl chrNW_004955408:11,654,630...11,745,262 		JBrowse link
G Adam28 ADAM metallopeptidase domain 28 treatment
disease_progression
exacerbates		 ISO protein:increased expression:lung RGD PMID:20112342 PMID:26800504 PMID:29882245 PMID:30190423 RGD:11531771 RGD:153297792 RGD:153297794 RGD:153297795 NCBI chrNW_004955403:47,304,711...47,409,369
Ensembl chrNW_004955403:47,319,382...47,409,380 		JBrowse link
G Adamtsl3 ADAMTS like 3 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chrNW_004955416:12,818,153...13,132,960
Ensembl chrNW_004955416:12,820,138...13,131,826 		JBrowse link
G Adgrg6 adhesion G protein-coupled receptor G6 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chrNW_004955436:17,804,548...17,931,667
Ensembl chrNW_004955436:17,805,068...17,931,665 		JBrowse link
G Ahcy adenosylhomocysteinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955422:26,992,295...27,013,100
Ensembl chrNW_004955422:26,992,295...27,013,100 		JBrowse link
G Ahr aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12597446 NCBI chrNW_004955410:20,428,531...20,459,482
Ensembl chrNW_004955410:20,428,546...20,456,836 		JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 disease_progression ISO RGD PMID:30727821 RGD:27226687 NCBI chrNW_004955464:12,715,238...12,729,034
Ensembl chrNW_004955464:12,714,717...12,729,662 		JBrowse link
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chrNW_004955447:9,327...21,212 JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955507:1,892,087...1,946,526
Ensembl chrNW_004955507:1,892,061...1,946,703 		JBrowse link
G Alk ALK receptor tyrosine kinase ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chrNW_004955469:11,049,373...11,751,235
Ensembl chrNW_004955469:11,047,048...11,548,233 		JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chrNW_004955467:8,876,186...8,887,980
Ensembl chrNW_004955467:8,876,027...8,888,033 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chrNW_004955546:2,495,226...2,550,909
Ensembl chrNW_004955546:2,494,819...2,550,909 		JBrowse link
G Alx4 ALX homeobox 4 disease_progression ISO RGD PMID:18978557 RGD:153350135 NCBI chrNW_004955422:3,278,615...3,290,799
Ensembl chrNW_004955422:3,278,615...3,291,714 		JBrowse link
G Anapc2 anaphase promoting complex subunit 2 severity ISO mRNA:decreased expression:lung (human) RGD PMID:12036940 RGD:14696682 NCBI chrNW_004955513:5,183,472...5,194,253
Ensembl chrNW_004955513:5,183,472...5,194,253 		JBrowse link
G Anp32a acidic nuclear phosphoprotein 32 family member A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955450:7,449,368...7,484,524 JBrowse link
G Anxa1 annexin A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chrNW_004955512:5,686,508...5,703,645 JBrowse link
G Anxa5 annexin A5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chrNW_004955428:18,873,782...18,907,955
Ensembl chrNW_004955428:18,873,782...18,907,955 		JBrowse link
G Apc APC regulator of WNT signaling pathway ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chrNW_004955418:2,567,804...2,675,062
Ensembl chrNW_004955418:2,566,975...2,674,832 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955550:1,273,170...1,275,843
Ensembl chrNW_004955550:1,273,284...1,279,743 		JBrowse link
G Apoa1 apolipoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chrNW_004955412:18,170,331...18,172,298
Ensembl chrNW_004955412:18,170,331...18,172,298 		JBrowse link
G Apoc3 apolipoprotein C3 ISO protein:altered glycosylation:: RGD PMID:19322776 RGD:153344619 NCBI chrNW_004955412:18,165,667...18,168,015
Ensembl chrNW_004955412:18,165,667...18,168,015 		JBrowse link
G Aqp4 aquaporin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955772:1,160...10,709
Ensembl chrNW_004955772:1,159...10,709 		JBrowse link
G Arg1 arginase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955436:12,235,767...12,247,817
Ensembl chrNW_004955436:12,235,767...12,251,972 		JBrowse link
G Arhgap35 Rho GTPase activating protein 35 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chrNW_004955574:915,604...984,744
Ensembl chrNW_004955574:915,325...984,744 		JBrowse link
G Arhgap44 Rho GTPase activating protein 44 ISO mRNA:decreased expression:lung (human) RGD PMID:28527113 RGD:401901290 NCBI chrNW_004955467:4,428,738...4,590,877
Ensembl chrNW_004955467:4,430,087...4,522,611 		JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chrNW_004955553:1,893,767...1,897,175
Ensembl chrNW_004955553:1,892,670...1,897,175 		JBrowse link
G Atrx ATRX chromatin remodeler disease_progression ISO RGD PMID:31374064 RGD:127285382 NCBI chrNW_004955557:947,368...1,252,701
Ensembl chrNW_004955557:947,167...1,252,724 		JBrowse link
G Axin2 axin 2 disease_progression
susceptibility		 ISO DNA:SNPs::1712 +19 G>A,148 C>T(human)
DNA:SNP:cds:p.P50S(human)		 RGD PMID:16820935 PMID:30346805 RGD:151356655 RGD:151356657 NCBI chrNW_004955478:4,952,551...4,982,223
Ensembl chrNW_004955478:4,952,488...4,982,225 		JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding ISO mRNA,protein:increased expression:lung RGD PMID:17724461 RGD:153350134 NCBI chrNW_004955573:902,153...910,481
Ensembl chrNW_004955573:899,798...912,272 		JBrowse link
G Bap1 BRCA1 associated deubiquitinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231345 NCBI chrNW_004955430:2,391,970...2,400,645
Ensembl chrNW_004955430:2,390,524...2,400,645 		JBrowse link
G Bhlhe41 basic helix-loop-helix family member e41 ISO mRNA:decreased expression:lung (human) RGD PMID:18223678 RGD:151665316 NCBI chrNW_004955413:21,100,021...21,103,358 JBrowse link
G Birc3 baculoviral IAP repeat containing 3 exacerbates ISO mRNA:increased expression:B cell (human) RGD PMID:33098370 RGD:153323293 NCBI chrNW_004955412:5,624,865...5,643,520
Ensembl chrNW_004955412:5,628,973...5,643,410 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:12068308 PMID:12198537 PMID:12447372 PMID:12460918 PMID:12460919 More... NCBI chrNW_004955494:2,567,238...2,712,708 JBrowse link
G Btk Bruton tyrosine kinase exacerbates
susceptibility		 ISO mRNA:decreased expression:lung (human) RGD PMID:31803536 PMID:32351880 RGD:151347848 RGD:151347849 NCBI chrNW_004955503:7,483,819...7,515,085
Ensembl chrNW_004955503:7,482,793...7,515,120 		JBrowse link
G Bzw2 basic leucine zipper and W2 domains 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955410:19,833,008...19,874,647
Ensembl chrNW_004955410:19,833,008...19,878,691 		JBrowse link
G Cadm1 cell adhesion molecule 1 ISO DNA, mRNA:hypermethylation, decreased expression:promoter:liver RGD PMID:16814249 RGD:2289096 NCBI chrNW_004955412:16,673,401...17,005,082
Ensembl chrNW_004955412:16,669,099...17,005,014 		JBrowse link
G Calr calreticulin treatment ISO human cells and recombinant gene in a mouse model RGD PMID:18245558 RGD:150521698 NCBI chrNW_004955415:31,985,147...31,989,372
Ensembl chrNW_004955415:31,985,147...31,989,372 		JBrowse link
G Capg capping actin protein, gelsolin like ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chrNW_004955424:2,064,672...2,080,192
Ensembl chrNW_004955424:2,072,035...2,080,086 		JBrowse link
G Cbx5 chromobox 5 disease_progression ISO mRNA,protein:increased expression:lung: RGD PMID:22900142 RGD:9586743 NCBI chrNW_004955458:1,486,951...1,529,649
Ensembl chrNW_004955458:1,486,951...1,505,653 		JBrowse link
G Cbx7 chromobox 7 ISO mRNA,DNA:decreased expression, loss of heterozygosity:lung: RGD PMID:22214847 RGD:9587356 NCBI chrNW_004955413:25,079,627...25,100,039
Ensembl chrNW_004955413:25,086,186...25,100,039 		JBrowse link
G Ccnd1 cyclin D1 disease_progression
treatment		 ISO RGD PMID:19355812 PMID:26681199 RGD:11536846 RGD:13434927 NCBI chrNW_004955422:16,449,921...16,462,676
Ensembl chrNW_004955422:16,448,770...16,463,300 		JBrowse link
G Ccnd2 cyclin D2 disease_progression ISO RGD PMID:30308939 RGD:151665105 NCBI chrNW_004955413:2,083,351...2,108,450
Ensembl chrNW_004955413:2,083,351...2,103,430 		JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955426:132,106...144,251
Ensembl chrNW_004955426:131,871...144,354 		JBrowse link
G Cd44 CD44 molecule (IN blood group) disease_progression ISO mRNA:increased expression:lung (human)
mRNA:splice variants:lung		 RGD PMID:18091389 PMID:29537891 RGD:149735539 RGD:2289345 NCBI chrNW_004955422:11,106,061...11,189,951 JBrowse link
G Cdc73 cell division cycle 73 exacerbates ISO mRNA:decreased expression:lung (human) RGD PMID:21692036 RGD:150537041 NCBI chrNW_004955406:30,533,919...30,665,812
Ensembl chrNW_004955406:30,533,060...30,665,812 		JBrowse link
G Cdh1 cadherin 1 ISO DNA:increased methylation RGD PMID:16329148 RGD:1599556 NCBI chrNW_004955484:7,782,409...7,861,082
Ensembl chrNW_004955484:7,782,772...7,860,967 		JBrowse link
G Cdk12 cyclin dependent kinase 12 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar NCBI chrNW_004955451:14,244,392...14,345,885
Ensembl chrNW_004955451:14,244,978...14,309,689 		JBrowse link
G Cdk4 cyclin dependent kinase 4 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:5377176 PMID:7652577 PMID:8528263 PMID:8968104 PMID:9228064 More... NCBI chrNW_004955458:5,457,927...5,460,718
Ensembl chrNW_004955458:5,453,732...5,460,718 		JBrowse link
G Cdk6 cyclin dependent kinase 6 ISO protein:increased expression:lung RGD PMID:10574260 RGD:13464325 NCBI chrNW_004955432:9,521,794...9,727,772
Ensembl chrNW_004955432:9,521,794...9,726,417 		JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 susceptibility
ameliorates		 ISO DNA:missense mutation:CDS:p.D140E (rs7479004) (human)
human cells in a mouse model
mRNA:increased expression:lung (human)		 RGD PMID:28486105 PMID:29667179 PMID:32228507 RGD:151660359 RGD:153323299 RGD:153323307 NCBI chrNW_004955413:4,191,619...4,228,225
Ensembl chrNW_004955413:4,191,619...4,228,225 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit susceptibility ISO DNA:SNP: :rs8042374(human)
associated with smoking; DNA:SNP: :rs1051730(human)
ClinVar Annotator: match by term: Lung adenocarcinoma		 RGD
ClinVar		 PMID:20554942 PMID:24686516 PMID:27993330 RGD:150527848 RGD:151347530 NCBI chrNW_004955450:979,630...1,011,316
Ensembl chrNW_004955450:977,075...1,011,372 		JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit susceptibility
disease_progression		 ISO ClinVar Annotator: match by term: Lung adenocarcinoma
DNA:SNP: :rs503464(human)
DNA:SNP:cds: p.D398N(human)
associated with smoking; DNA:SNPs: :rs2036527, rs684513, rs667282(human)		 ClinVar
RGD		 PMID:19577767 PMID:20554942 PMID:23314339 PMID:27993330 RGD:150524359 RGD:150527848 RGD:150527849 NCBI chrNW_004955450:945,400...974,129
Ensembl chrNW_004955450:946,898...974,457 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit ISO DNA:hypomethylation:promoter:
mRNA:increased expression:lung		 RGD PMID:20124469 PMID:22945651 RGD:150527851 RGD:151361154 NCBI chrNW_004955450:1,013,897...1,030,232
Ensembl chrNW_004955450:1,013,607...1,030,282 		JBrowse link
G Clptm1l CLPTM1 like ameliorates
susceptibility
no_association		 ISO DNA:SNP:: rs31490(human)
DNA:SNP:: rs4975616(human)
DNA:SNP::rs401681(human)
mRNA:increased expression:lung
DNA:SNP::rs77518573(human)
DNA:SNP: :rs401681(human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:19955392 PMID:22675468 PMID:23738012 PMID:23908149 PMID:24366883 More... RGD:150530483 RGD:150530485 RGD:150530498 RGD:150530499 RGD:150530502 RGD:150530635 RGD:150537098 NCBI chrNW_004955504:677,824...695,660
Ensembl chrNW_004955504:677,772...695,660 		JBrowse link
G Cmtr2 cap methyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chrNW_004955484:3,999,655...4,006,632
Ensembl chrNW_004955484:3,999,665...4,006,632 		JBrowse link
G Col10a1 collagen type X alpha 1 chain disease_progression ISO mRNA:increased expression:lung RGD PMID:33324550 RGD:150429752 NCBI chrNW_004955526:641,577...679,295 JBrowse link
G Crebbp CREB binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chrNW_004955442:13,559,496...13,691,913
Ensembl chrNW_004955442:13,559,496...13,692,004 		JBrowse link
G Csf1r colony stimulating factor 1 receptor ISO protein:increased expression:lung (human) RGD PMID:23702648 RGD:150524280 NCBI chrNW_004955415:4,434,486...4,462,505
Ensembl chrNW_004955415:4,434,453...4,461,751 		JBrowse link
G Csrp3 cysteine and glycine rich protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955476:155,913...176,122
Ensembl chrNW_004955476:154,917...176,616 		JBrowse link
G Ctnnb1 catenin beta 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma
ClinVar Annotator: match by term: Adenocarcinoma of lung		 ClinVar PMID:10192393 PMID:25741868 PMID:26619011 NCBI chrNW_004955420:29,030,716...29,047,447
Ensembl chrNW_004955420:29,030,716...29,047,449 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 exacerbates ISO protein:increased expression:lung (human)
mRNA:increased expression:lung (human)		 RGD PMID:19716197 PMID:30103827 RGD:152023735 RGD:152177480 NCBI chrNW_004955440:3,456,165...3,460,024
Ensembl chrNW_004955440:3,455,153...3,460,109 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chrNW_004955462:13,578,638...13,644,834
Ensembl chrNW_004955462:13,584,724...13,642,968 		JBrowse link
G Dll4 delta like canonical Notch ligand 4 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chrNW_004955416:7,807,049...7,816,346
Ensembl chrNW_004955416:7,807,049...7,817,420 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:21067377 PMID:21518476 PMID:22160010 PMID:22722925 PMID:22744846 More... NCBI chrNW_004955469:7,264,431...7,367,059
Ensembl chrNW_004955469:7,269,952...7,367,059 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta susceptibility ISO DNA:SNPs,haplotype:promoter:-283T >C,-579G>T(human) RGD PMID:15528220 RGD:9589086 NCBI chrNW_004955422:28,380,595...28,427,012
Ensembl chrNW_004955422:28,380,591...28,421,301 		JBrowse link
G Dok1 docking protein 1 disease_progression ISO RGD PMID:20139980 RGD:152177521 NCBI chrNW_004955424:11,233,601...11,236,397
Ensembl chrNW_004955424:11,232,376...11,236,885 		JBrowse link
G Dok2 docking protein 2 disease_progression
exacerbates		 ISO mRNA:decreased expression:lung (human) RGD PMID:20139980 PMID:24255704 PMID:30475228 RGD:152177492 RGD:152177493 RGD:152177521 NCBI chrNW_004955403:45,410,689...45,421,366
Ensembl chrNW_004955403:45,410,279...45,415,067 		JBrowse link
G Dok3 docking protein 3 disease_progression ISO RGD PMID:20139980 RGD:152177521 NCBI chrNW_004955408:29,740,606...29,747,986
Ensembl chrNW_004955408:29,740,449...29,747,986 		JBrowse link
G Dot1l DOT1 like histone lysine methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chrNW_004955495:5,907,486...5,958,241
Ensembl chrNW_004955495:5,909,880...5,959,027 		JBrowse link
G E2f1 E2F transcription factor 1 ISO mRNA:increased expression:lung RGD PMID:26695082 RGD:13464334 NCBI chrNW_004955422:27,638,625...27,643,261
Ensembl chrNW_004955422:27,633,827...27,642,241 		JBrowse link
G E2f3 E2F transcription factor 3 ISO RGD PMID:16938365 RGD:13464341 NCBI chrNW_004955483:6,039,569...6,116,000
Ensembl chrNW_004955483:6,042,863...6,117,479 		JBrowse link
G Eef2 eukaryotic translation elongation factor 2 exacerbates ISO protein:increased expression:lung (human) RGD PMID:21554491 RGD:153298904 NCBI chrNW_004955495:4,800,103...4,807,714
Ensembl chrNW_004955495:4,799,922...4,807,252 		JBrowse link
G Eef2k eukaryotic elongation factor 2 kinase ameliorates ISO Human cells in mouse model RGD PMID:30522114 RGD:153298964 NCBI chrNW_004955493:865,830...922,765
Ensembl chrNW_004955493:865,830...922,765 		JBrowse link
G Egf epidermal growth factor ISO DNA:polymorphism: :p.A61G (human) RGD PMID:26625757 RGD:11538684 NCBI chrNW_004955496:325,954...401,430
Ensembl chrNW_004955496:328,075...401,569 		JBrowse link
G Egfr epidermal growth factor receptor disease_progression ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Adenocarcinoma of lung, somatic | ClinVar Annotator: match by term: Lung adenocarcinoma RGD
ClinVar		 PMID:11423618 PMID:15118073 PMID:15118125 PMID:15272417 PMID:15329413 More... RGD:126790475 NCBI chrNW_004955456:321,222...456,431 JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 disease_progression ISO RGD PMID:20940408 RGD:9589170 NCBI chrNW_004955437:396,736...411,144
Ensembl chrNW_004955437:396,742...411,144 		JBrowse link
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955482:5,380,121...5,388,588
Ensembl chrNW_004955482:5,380,121...5,388,588 		JBrowse link
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 NCBI chrNW_004955469:9,328,900...9,334,463
Ensembl chrNW_004955469:9,328,943...9,334,315 		JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 NCBI chrNW_004955420:23,313,405...23,322,748
Ensembl chrNW_004955420:23,309,378...23,322,698 		JBrowse link
G Eif3e eukaryotic translation initiation factor 3 subunit E ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955417:30,823,555...30,858,975
Ensembl chrNW_004955417:30,822,027...30,858,975 		JBrowse link
G Eml4 EMAP like 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22980554 PMID:22999080 NCBI chrNW_004955441:9,633,906...9,715,866
Ensembl chrNW_004955441:9,640,899...9,713,596 		JBrowse link
G Emx2 empty spiracles homeobox 2 exacerbates ISO mRNA,protein:decreased expression:lung (human) RGD PMID:21726823 RGD:153323303 NCBI chrNW_004955431:22,192,446...22,199,141
Ensembl chrNW_004955431:22,192,446...22,199,279 		JBrowse link
G Eno1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 PMID:27602772 NCBI chrNW_004955486:4,275,371...4,287,152
Ensembl chrNW_004955486:4,274,238...4,289,809 		JBrowse link
G Ep300 E1A binding protein p300 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chrNW_004955413:26,647,553...26,727,875
Ensembl chrNW_004955413:26,648,339...26,727,933 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 disease_progression ISO ClinVar Annotator: match by term: Lung adenocarcinoma RGD
ClinVar		 PMID:15457249 PMID:15753357 PMID:16638863 PMID:18334834 PMID:22325357 More... RGD:126790475 NCBI chrNW_004955451:14,442,816...14,456,009
Ensembl chrNW_004955451:14,442,816...14,459,379 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 disease_progression ISO RGD PMID:26824984 RGD:126790475 NCBI chrNW_004955458:3,683,126...3,701,752
Ensembl chrNW_004955458:3,683,126...3,702,978 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 disease_progression ISO RGD PMID:26824984 RGD:126790475 NCBI chrNW_004955457:3,177,905...4,236,152
Ensembl chrNW_004955457:3,177,991...4,228,558 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:21327329 NCBI chrNW_004955555:2,393,510...2,430,180
Ensembl chrNW_004955555:2,393,278...2,406,582 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor ISO mRNA, protein:increased expression:lung (human) RGD PMID:31615563 RGD:155260344 NCBI chrNW_004955556:745,175...812,215
Ensembl chrNW_004955556:748,231...813,133 		JBrowse link
G Ercc6l ERCC excision repair 6 like, spindle assembly checkpoint helicase exacerbates ISO mRNA:increased expression:lung (human) RGD PMID:35150321 RGD:155260359 NCBI chrNW_004955475:11,596,405...11,629,186 JBrowse link
G Ergic3 ERGIC and golgi 3 ameliorates
disease_progression		 ISO mRNA,protein:increased expression:lung (human) RGD PMID:23374247 PMID:27588471 RGD:151708716 RGD:153323314 NCBI chrNW_004955422:25,884,138...25,893,237
Ensembl chrNW_004955422:25,884,080...25,893,236 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chrNW_004955482:8,572,227...8,579,589
Ensembl chrNW_004955482:8,572,227...8,579,946 		JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 ameliorates ISO RGD PMID:33573689 RGD:155791670 NCBI chrNW_004955403:50,306,726...50,328,015
Ensembl chrNW_004955403:50,307,681...50,372,822 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit disease_progression ISO RGD PMID:24097870 RGD:126781716 NCBI chrNW_004955491:4,215,353...4,292,229
Ensembl chrNW_004955491:4,215,298...4,292,235 		JBrowse link
G Fas Fas cell surface death receptor ISO mRNA:decreased expression:lung (human) RGD PMID:29254206 RGD:151665107 NCBI chrNW_004955425:3,961,671...3,987,513
Ensembl chrNW_004955425:3,961,013...3,987,455 		JBrowse link
G Fasn fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955506:1,063,002...1,079,939
Ensembl chrNW_004955506:1,063,002...1,079,939 		JBrowse link
G Fbl fibrillarin ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955578:1,176,713...1,186,873
Ensembl chrNW_004955578:1,176,713...1,186,873 		JBrowse link
G Fes FES proto-oncogene, tyrosine kinase treatment ISO human cells in a mouse model RGD PMID:31573955 RGD:153323295 NCBI chrNW_004955416:14,948,121...14,959,035
Ensembl chrNW_004955416:14,948,123...14,960,005 		JBrowse link
G Fgf10 fibroblast growth factor 10 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chrNW_004955446:18,163,117...18,244,840
Ensembl chrNW_004955446:18,163,117...18,245,199 		JBrowse link
G Fgf18 fibroblast growth factor 18 ISO mRNA:decreased expression:lung (human) RGD PMID:19296538 RGD:150429981 NCBI chrNW_004955408:24,225,459...24,260,057
Ensembl chrNW_004955408:24,225,459...24,260,092 		JBrowse link
G Fgf9 fibroblast growth factor 9 disease_progression ISO mRNA:decreased expression:lung (human)
protein:increased expression:lung (human)		 RGD PMID:19296538 PMID:19358281 PMID:20464547 RGD:150429981 RGD:152177688 RGD:152975620 NCBI chrNW_004955497:2,199,424...2,232,088
Ensembl chrNW_004955497:2,199,409...2,235,893 		JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 disease_progression
exacerbates		 ISO human cells in mouse model
DNA:SNP:exon 9: p.G388R (rs351855)(human)
DNA:SNP:exon 9: p.G388R (human)		 RGD PMID:16061909 PMID:19296538 PMID:29402970 RGD:150429976 RGD:150429981 RGD:150429984 NCBI chrNW_004955408:29,370,480...29,383,531
Ensembl chrNW_004955408:29,370,468...29,383,971 		JBrowse link
G Fkbp11 FKBP prolyl isomerase 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955500:7,744,429...7,747,289 JBrowse link
G Flt1 fms related receptor tyrosine kinase 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chrNW_004955497:7,653,309...7,831,737
Ensembl chrNW_004955497:7,653,248...7,831,472 		JBrowse link
G Foxa1 forkhead box A1 ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung		 CTD
RGD		 PMID:12234996 PMID:29072684 PMID:34254728 RGD:151665758 RGD:151665822 NCBI chrNW_004955409:23,598,127...23,599,827
Ensembl chrNW_004955409:23,598,127...23,599,461 		JBrowse link
G Foxo3 forkhead box O3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19380174 NCBI chrNW_004955411:33,655,958...33,770,829
Ensembl chrNW_004955411:33,655,958...33,770,829 		JBrowse link
G Foxp1 forkhead box P1 ISO mRNA:decreased expression:lung (rat) RGD PMID:16023287 RGD:11561933 NCBI chrNW_004955421:16,595,445...17,075,923
Ensembl chrNW_004955421:16,595,471...17,075,923 		JBrowse link
G Foxp2 forkhead box P2 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chrNW_004955432:20,205,369...20,589,608
Ensembl chrNW_004955432:20,334,237...20,589,352 		JBrowse link
G Foxp4 forkhead box P4 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chrNW_004955437:8,029,346...8,056,243
Ensembl chrNW_004955437:8,014,939...8,057,033 		JBrowse link
G Frzb frizzled related protein severity ISO mRNA:decreased expression:lung (human) RGD PMID:27623992 RGD:32716395 NCBI chrNW_004955403:14,598,765...14,627,997
Ensembl chrNW_004955403:14,598,765...14,631,154 		JBrowse link
G Fubp1 far upstream element binding protein 1 ISO mRNA:decreased expression:lung (human) RGD PMID:32481602 RGD:151361197 NCBI chrNW_004955423:15,245,645...15,278,628
Ensembl chrNW_004955423:15,245,610...15,278,628 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955413:4,162,467...4,166,783
Ensembl chrNW_004955413:4,162,467...4,166,783 		JBrowse link
G Gar1 GAR1 ribonucleoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955496:476,061...483,030
Ensembl chrNW_004955496:475,579...483,030 		JBrowse link
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955407:32,944,638...32,975,142
Ensembl chrNW_004955407:32,944,164...32,973,863 		JBrowse link
G Gjb2 gap junction protein beta 2 ISO DNA, mRNA:hypermethylation, decreased expression:lung RGD PMID:16637067 RGD:11568669 NCBI chrNW_004955497:987,213...989,477
Ensembl chrNW_004955497:988,422...989,099 		JBrowse link
G Gng11 G protein subunit gamma 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 NCBI chrNW_004955432:10,664,251...10,668,749
Ensembl chrNW_004955432:10,664,170...10,668,953 		JBrowse link
G Gnpnat1 glucosamine-phosphate N-acetyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955409:10,406,248...10,424,431
Ensembl chrNW_004955409:10,406,723...10,424,431 		JBrowse link
G Golm1 golgi membrane protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955432:1,434,759...1,497,916
Ensembl chrNW_004955432:1,439,578...1,496,371 		JBrowse link
G Gpi glucose-6-phosphate isomerase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955468:3,980,999...4,007,553
Ensembl chrNW_004955468:3,980,999...4,008,652 		JBrowse link
G Gpx3 glutathione peroxidase 3 ISO mRNA:decreased expression:lung (human) RGD PMID:23374247 RGD:151708716 NCBI chrNW_004955408:2,622,162...2,629,088
Ensembl chrNW_004955408:2,622,741...2,629,032 		JBrowse link
G Grwd1 glutamate rich WD repeat containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955559:2,033,743...2,039,493
Ensembl chrNW_004955559:2,029,414...2,039,493 		JBrowse link
G Hells helicase, lymphoid specific ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955507:995,389...1,034,852
Ensembl chrNW_004955507:990,429...1,034,852 		JBrowse link
G Hk1 hexokinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955437:21,733,314...21,824,303
Ensembl chrNW_004955437:21,731,584...21,816,324 		JBrowse link
G Hk2 hexokinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955424:10,897,528...10,966,025
Ensembl chrNW_004955424:10,897,485...10,966,025 		JBrowse link
G Hmgb2 high mobility group box 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 PMID:27602772 NCBI chrNW_004955403:33,656,314...33,659,115
Ensembl chrNW_004955403:33,656,300...33,659,428 		JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955458:1,530,163...1,536,874 JBrowse link
G Hoxb7 homeobox B7 severity ISO protein:increased expression:lung epithelium (human) RGD PMID:22911672 RGD:10402176 NCBI chrNW_004955451:12,630,276...12,634,641
Ensembl chrNW_004955451:12,630,276...12,634,634 		JBrowse link
G Hras HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:1904555 PMID:3510078 PMID:11150980 PMID:12835555 PMID:16155195 More... NCBI chrNW_004955476:11,508,446...11,510,333
Ensembl chrNW_004955476:11,508,126...11,510,333 		JBrowse link
G Hsd17b10 hydroxysteroid 17-beta dehydrogenase 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chrNW_004955475:478,690...481,029
Ensembl chrNW_004955475:478,690...481,029 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 ISO mRNA:increased expression:lung (human) RGD PMID:23374247 RGD:151708716 NCBI chrNW_004955405:38,629,691...38,645,202
Ensembl chrNW_004955405:38,629,691...38,645,202 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chrNW_004955844:8,094...9,565
Ensembl chrNW_004955844:7,790...10,004 		JBrowse link
G Htr4 5-hydroxytryptamine receptor 4 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chrNW_004955415:5,745,056...5,802,409
Ensembl chrNW_004955415:5,685,309...5,802,409 		JBrowse link
G Htra1 HtrA serine peptidase 1 disease_progression ISO human cells in mouse model RGD PMID:24356998 RGD:152975621 NCBI chrNW_004955477:761,127...808,396
Ensembl chrNW_004955477:761,127...808,994 		JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 disease_progression ISO mRNA:increased expression:lung (human)
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma
protein:increased expression:blood plasma (human)		 RGD
ClinVar		 PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20946881 More... RGD:149735539 RGD:149735540 NCBI chrNW_004955457:6,851,542...6,869,452
Ensembl chrNW_004955457:6,851,517...6,872,367 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 severity ISO protein:increased expression:lung (human)
protein:increased expression:blood serum (human)		 RGD PMID:29465809 PMID:30128035 RGD:149735564 RGD:149735567 NCBI chrNW_004955416:15,197,611...15,212,919
Ensembl chrNW_004955416:15,197,366...15,223,363 		JBrowse link
G Igf2r insulin like growth factor 2 receptor ISO mRNA:deletions: :c.3698_4902del, c.3366_4902del, c.3817_4697del (rat) RGD PMID:12503077 RGD:1298968 NCBI chrNW_004955439:20,754,915...20,874,759
Ensembl chrNW_004955439:20,752,855...20,851,281 		JBrowse link
G Ikzf1 IKAROS family zinc finger 1 exacerbates
ameliorates		 ISO protein:increased expression:lung (human)
mRNA:increased expression:lung (human)		 RGD PMID:32787735 PMID:33738286 RGD:150540324 RGD:151347632 NCBI chrNW_004955456:3,617,988...3,721,791
Ensembl chrNW_004955456:3,635,380...3,721,791 		JBrowse link
G Il1r2 interleukin 1 receptor type 2 severity
disease_progression		 ISO mRNA:increased expression:lung (human)
mRNA:altered expression:lung (human)		 RGD PMID:29942094 PMID:31921619 RGD:152998982 RGD:152998998 NCBI chrNW_004955470:7,518,565...7,562,219
Ensembl chrNW_004955470:7,518,663...7,559,470 		JBrowse link
G Impdh2 inosine monophosphate dehydrogenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955532:1,047,138...1,051,980
Ensembl chrNW_004955532:1,045,833...1,051,978 		JBrowse link
G Ipo4 importin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955409:36,214,704...36,223,714
Ensembl chrNW_004955409:36,214,704...36,223,714 		JBrowse link
G Ipo5 importin 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955404:12,416,755...12,480,281
Ensembl chrNW_004955404:12,416,755...12,459,452 		JBrowse link
G Iqsec1 IQ motif and Sec7 domain ArfGEF 1 disease_progression ISO RGD PMID:24902879 RGD:153350085 NCBI chrNW_004955429:13,246,585...13,373,189
Ensembl chrNW_004955429:13,246,294...13,376,568 		JBrowse link
G Irak3 interleukin 1 receptor associated kinase 3 ISO mRNA:increased expression:lung (human) RGD PMID:21278795 RGD:36049796 NCBI chrNW_004955458:12,839,995...12,880,285
Ensembl chrNW_004955458:12,846,237...12,879,316 		JBrowse link
G Ireb2 iron responsive element binding protein 2 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chrNW_004955450:852,554...898,908
Ensembl chrNW_004955450:852,554...900,011 		JBrowse link
G Jak2 Janus kinase 2 treatment ISO human cells in mouse model RGD PMID:27025877 RGD:11574134 NCBI chrNW_004955434:9,227,897...9,341,208
Ensembl chrNW_004955434:9,227,595...9,341,208 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 NCBI chrNW_004955415:31,876,508...31,878,289
Ensembl chrNW_004955415:31,876,793...31,877,836 		JBrowse link
G Kcnj4 potassium inwardly rectifying channel subfamily J member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30512237 NCBI chrNW_004955413:24,605,887...24,634,524
Ensembl chrNW_004955413:24,605,887...24,634,524 		JBrowse link
G Klf5 KLF transcription factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chrNW_004955404:33,642,604...33,665,445
Ensembl chrNW_004955404:33,644,077...33,658,094 		JBrowse link
G Kmt2c lysine methyltransferase 2C onset
disease_progression		 ISO RGD PMID:30821106 PMID:32867667 RGD:151356760 RGD:151356761 NCBI chrNW_004955491:6,245,408...6,420,535
Ensembl chrNW_004955491:6,247,249...6,402,470 		JBrowse link
G Kpna2 karyopherin subunit alpha 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955478:7,121,432...7,134,327
Ensembl chrNW_004955478:7,121,432...7,134,327 		JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Adenocarcinoma of lung
ClinVar Annotator: match by term: Lung adenocarcinoma		 ClinVar PMID:2278970 PMID:3122217 PMID:6320174 PMID:11745231 PMID:12460918 More... NCBI chrNW_004955413:20,298,852...20,328,756
Ensembl chrNW_004955413:20,298,824...20,328,758 		JBrowse link
G Ldha lactate dehydrogenase A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955414:33,087,745...33,100,846 JBrowse link
G Lect2 leukocyte cell derived chemotaxin 2 ameliorates ISO human cells in mouse model RGD PMID:30453282 RGD:153323337 NCBI chrNW_004955408:31,016,955...31,068,998
Ensembl chrNW_004955408:31,016,815...31,025,093 		JBrowse link
G Lmna lamin A/C ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chrNW_004955545:2,290,076...2,310,982
Ensembl chrNW_004955545:2,290,037...2,313,033 		JBrowse link
G Lmnb1 lamin B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955521:4,583,691...4,612,271
Ensembl chrNW_004955521:4,583,671...4,612,271 		JBrowse link
G LOC102009223 cytochrome P450 1B1 ISO protein:increased expression:lung (human) RGD PMID:19358281 RGD:152177688 NCBI chrNW_004955441:5,803,397...5,812,131
Ensembl chrNW_004955441:5,803,032...5,812,131 		JBrowse link
G LOC102012785 histone H1x ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955429:13,671,907...13,673,689
Ensembl chrNW_004955429:13,672,008...13,672,613 		JBrowse link
G LOC102013768 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial ameliorates ISO human cell line in a mouse model
mRNA:decreased expression:lung (human)
DNA:hypomethylation:promoter (human)		 RGD PMID:24736069 PMID:25519225 PMID:27793774 RGD:151361181 RGD:151665173 RGD:151665499 NCBI chrNW_004955445:4,874,583...4,891,723
Ensembl chrNW_004955445:4,873,942...4,891,780 		JBrowse link
G LOC102027549 serotransferrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chrNW_004955501:4,801,710...4,832,025
Ensembl chrNW_004955501:4,801,885...4,831,910 		JBrowse link
G Lrp1b LDL receptor related protein 1B disease_progression ISO DNA:mutations:multiple: (human) RGD PMID:18948947 RGD:11064706 NCBI chrNW_004955440:7,048,527...8,475,566
Ensembl chrNW_004955440:7,050,135...8,475,122 		JBrowse link
G Lrrc56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma		 ClinVar PMID:1904555 PMID:3510078 PMID:11150980 PMID:12835555 PMID:16155195 More... NCBI chrNW_004955476:11,493,299...11,507,022
Ensembl chrNW_004955476:11,491,688...11,506,700 		JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung (human)		 ClinVar
CTD
RGD		 PMID:22135231 PMID:26619011 PMID:29254206 RGD:151665107 NCBI chrNW_004955450:9,181,851...9,205,277
Ensembl chrNW_004955450:9,181,851...9,239,648 		JBrowse link
G Map2k4 mitogen-activated protein kinase kinase 4 severity ISO RGD PMID:12231543 PMID:21896780 RGD:150429783 RGD:150429821 NCBI chrNW_004955467:5,188,036...5,295,570
Ensembl chrNW_004955467:5,187,356...5,307,692 		JBrowse link
G Map2k7 mitogen-activated protein kinase kinase 7 exacerbates ISO human gene in a mouse model RGD PMID:34236045 RGD:155230828 NCBI chrNW_004955563:1,352,638...1,361,598
Ensembl chrNW_004955563:1,352,638...1,361,598 		JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 exacerbates ISO RGD PMID:23533274 RGD:151356978 NCBI chrNW_004955429:21,717,153...21,739,349
Ensembl chrNW_004955429:21,716,958...21,741,585 		JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 exacerbates
ameliorates		 ISO mRNA, protein:increased expression:lung (human)
human cell line in a mouse model		 RGD PMID:22824148 PMID:28306189 PMID:33510968 RGD:151347677 RGD:151347678 RGD:151347681 NCBI chrNW_004955470:7,334,050...7,470,751
Ensembl chrNW_004955470:7,333,351...7,470,751 		JBrowse link
G Mapk14 mitogen-activated protein kinase 14 exacerbates ISO mRNA:increased expression:lung (human) RGD PMID:31969449 RGD:151665505 NCBI chrNW_004955437:3,836,331...3,884,083
Ensembl chrNW_004955437:3,838,232...3,884,083 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member severity
treatment		 ISO mRNA:increased expression:lung (human)
human cells in mouse model		 RGD PMID:31200834 RGD:151356911 NCBI chrNW_004955413:238,043...243,317 JBrowse link
G Meox1 mesenchyme homeobox 1 ISO CTD Direct Evidence: therapeutic CTD PMID:34837450 NCBI chrNW_004955451:17,013,180...17,022,131
Ensembl chrNW_004955451:17,012,982...17,022,186 		JBrowse link
G Mier3 MIER family member 3 ameliorates ISO RGD PMID:35117188 RGD:407571696 NCBI chrNW_004955446:10,962,336...10,992,645
Ensembl chrNW_004955446:10,961,436...10,992,971 		JBrowse link
G Mki67 marker of proliferation Ki-67 disease_progression ISO protein:altered expression:lung (human) RGD PMID:26942465 RGD:152999419 NCBI chrNW_004955477:5,847,288...5,875,970 JBrowse link
G Mlh1 mutL homolog 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chrNW_004955421:3,890,291...3,936,892
Ensembl chrNW_004955421:3,890,306...3,936,526 		JBrowse link
G Mrpl12 mitochondrial ribosomal protein L12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955506:1,400,439...1,404,409
Ensembl chrNW_004955506:1,398,445...1,404,409 		JBrowse link
G Mrps5 mitochondrial ribosomal protein S5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955470:3,419,052...3,443,481
Ensembl chrNW_004955470:3,416,731...3,443,298 		JBrowse link
G Ms4a1 membrane spanning 4-domains A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22514692 NCBI chrNW_004955511:5,252,934...5,263,961
Ensembl chrNW_004955511:5,258,341...5,267,113 		JBrowse link
G Msh2 mutS homolog 2 no_association ISO DNA:polymorphisms:promoter, intron:-118T>C, IVS1+9G>C (human)
DNA:polymorphisms:introns:IVS10+12A>G, IVS12-6T>C (human)		 RGD PMID:16614121 RGD:11065547 NCBI chrNW_004955441:14,188,315...14,247,608
Ensembl chrNW_004955441:14,187,805...14,247,698 		JBrowse link
G Msh3 mutS homolog 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21327329 NCBI chrNW_004955418:29,149,595...29,274,067
Ensembl chrNW_004955418:29,150,085...29,274,437 		JBrowse link
G Msh6 mutS homolog 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21327329 NCBI chrNW_004955441:14,451,207...14,471,316
Ensembl chrNW_004955441:14,451,307...14,471,227 		JBrowse link
G Muc1 mucin 1, cell surface associated ISO mRNA:increased expression:lung RGD PMID:8694545 RGD:5131260 NCBI chrNW_004955545:1,657,728...1,662,112 JBrowse link
G Muc4 mucin 4, cell surface associated disease_progression ISO protein:increased expression:trachea RGD PMID:17126950 RGD:5131208 NCBI chrNW_004955420:12,228,801...12,274,840 JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chrNW_004955476:11,061,405...11,084,294 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO human cell line in mouse model
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:20033209 PMID:26656844 PMID:27602772 RGD:7207787 NCBI chrNW_004955461:2,714,022...2,718,872
Ensembl chrNW_004955461:2,714,022...2,718,982 		JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor ameliorates
treatment		 ISO mouse cell line in a mouse model RGD PMID:30712876 PMID:32140881 RGD:150520172 RGD:150540309 NCBI chrNW_004955427:25,553,589...25,557,654
Ensembl chrNW_004955427:25,553,589...25,559,138 		JBrowse link
G Naa10 N-alpha-acetyltransferase 10, NatA catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955580:604,805...609,978
Ensembl chrNW_004955580:603,331...612,608 		JBrowse link
G Naip NLR family apoptosis inhibitory protein ameliorates ISO mRNA:increased expression:lung (human) RGD PMID:31964418 RGD:153344516 NCBI chrNW_004955575:249,659...283,378 JBrowse link
G Ncapg non-SMC condensin I complex subunit G ISO CTD Direct Evidence: marker/mechanism CTD PMID:34419073 NCBI chrNW_004955480:6,399,891...6,430,617
Ensembl chrNW_004955480:6,399,960...6,430,645 		JBrowse link
G Ncl nucleolin ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955453:4,154,627...4,164,253
Ensembl chrNW_004955453:4,154,627...4,164,253 		JBrowse link
G Nkx2-1 NK2 homeobox 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chrNW_004955409:24,612,490...24,616,360
Ensembl chrNW_004955409:24,612,635...24,616,430 		JBrowse link
G Nlrp3 NLR family pyrin domain containing 3 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chrNW_004955581:597,952...616,903
Ensembl chrNW_004955581:597,667...617,410 		JBrowse link
G Nop56 NOP56 ribonucleoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955415:13,637,505...13,642,809
Ensembl chrNW_004955415:13,637,595...13,643,938 		JBrowse link
G Nop58 NOP58 ribonucleoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955457:12,481,467...12,511,678
Ensembl chrNW_004955457:12,479,965...12,511,678 		JBrowse link
G Notch1 notch receptor 1 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chrNW_004955513:4,225,939...4,264,875
Ensembl chrNW_004955513:4,225,956...4,263,259 		JBrowse link
G Npm1 nucleophosmin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955408:24,151,070...24,218,783 JBrowse link
G Npm3 nucleophosmin/nucleoplasmin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955485:8,510,404...8,512,198 JBrowse link
G Nudt21 nudix hydrolase 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955433:14,220,356...14,234,423
Ensembl chrNW_004955433:14,216,974...14,234,611 		JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex disease_progression ISO RGD PMID:32226507 RGD:28912743 NCBI chrNW_004955462:13,082,874...13,142,709
Ensembl chrNW_004955462:13,082,047...13,142,944 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23951099 NCBI chrNW_004955561:1,277,362...1,282,949
Ensembl chrNW_004955561:1,277,365...1,282,793 		JBrowse link
G Pabpc4 poly(A) binding protein cytoplasmic 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955452:17,083,679...17,101,436
Ensembl chrNW_004955452:17,084,805...17,101,026 		JBrowse link
G Pacrg parkin coregulated ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:12719539 NCBI chrNW_004955439:18,152,719...18,664,026
Ensembl chrNW_004955439:18,153,227...18,663,780 		JBrowse link
G Pcbd1 pterin-4 alpha-carbinolamine dehydratase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955437:20,482,589...20,487,337
Ensembl chrNW_004955437:20,482,589...20,488,249 		JBrowse link
G Pign phosphatidylinositol glycan anchor biosynthesis class N ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955402:45,979,577...46,114,634
Ensembl chrNW_004955402:45,983,826...46,114,752 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chrNW_004955420:8,355,415...8,427,024
Ensembl chrNW_004955420:8,356,353...8,427,024 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO mRNA:decreased expression:lung RGD PMID:26695082 RGD:13464334 NCBI chrNW_004955446:1,020,707...1,098,327
Ensembl chrNW_004955446:1,020,043...1,098,820 		JBrowse link
G Pitx2 paired like homeodomain 2 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chrNW_004955457:15,803,493...15,823,193
Ensembl chrNW_004955457:15,803,219...15,823,310 		JBrowse link
G Plcg1 phospholipase C gamma 1 exacerbates ISO protein:decreased expression:lung (human) RGD PMID:33077911 RGD:151356960 NCBI chrNW_004955445:15,787,496...15,823,859
Ensembl chrNW_004955445:15,787,496...15,823,859 		JBrowse link
G Plod2 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 disease_progression ISO RGD PMID:29072684 RGD:151665822 NCBI chrNW_004955474:11,392,163...11,473,918
Ensembl chrNW_004955474:11,392,163...11,475,508 		JBrowse link
G Pold1 DNA polymerase delta 1, catalytic subunit exacerbates ISO protein:increased expression:lung (human) RGD PMID:33442399 RGD:153323317 NCBI chrNW_004955559:712,375...730,551
Ensembl chrNW_004955559:712,321...725,661 		JBrowse link
G Polr1d RNA polymerase I and III subunit D ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955497:7,029,556...7,030,128
Ensembl chrNW_004955497:7,029,557...7,029,931 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chrNW_004955496:6,934,542...7,059,745
Ensembl chrNW_004955496:6,908,224...7,059,816 		JBrowse link
G Prame PRAME nuclear receptor transcriptional regulator ISO mRNA:decreased expression:lung (human) RGD PMID:27241212 RGD:11535020 NCBI chrNW_004955455:6,921,420...6,930,453
Ensembl chrNW_004955455:6,921,052...6,930,537 		JBrowse link
G Prdm1 PR/SET domain 1 exacerbates ISO RGD PMID:28378641 RGD:150530469 NCBI chrNW_004955411:31,434,503...31,455,995
Ensembl chrNW_004955411:31,434,503...31,456,056 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:10072423 PMID:12719539 PMID:20301651 PMID:22956510 PMID:25741868 More... NCBI chrNW_004955439:18,664,230...19,953,358
Ensembl chrNW_004955439:18,664,379...19,951,152 		JBrowse link
G Psat1 phosphoserine aminotransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955512:1,132,452...1,155,405
Ensembl chrNW_004955512:1,132,390...1,155,412 		JBrowse link
G Ptch1 patched 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 PMID:28492532 NCBI chrNW_004955422:22,362,330...22,418,062
Ensembl chrNW_004955422:22,362,221...22,427,622 		JBrowse link
G Pten phosphatase and tensin homolog ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chrNW_004955425:5,007,811...5,091,829
Ensembl chrNW_004955425:5,014,147...5,091,829 		JBrowse link
G Ptpn13 protein tyrosine phosphatase non-receptor type 13 susceptibility
exacerbates		 ISO DNA:missense mutations:cds:p.I1522M, p.Y2081D (human)
mRNA,protein:decreased expression:lung		 RGD PMID:19672627 PMID:22245727 PMID:33536603 RGD:152176663 RGD:152176665 RGD:152975626 NCBI chrNW_004955474:2,988,109...3,140,520
Ensembl chrNW_004955474:2,988,639...3,140,513 		JBrowse link
G Ptprb protein tyrosine phosphatase receptor type B disease_progression ISO mRNA:altered expression:lung (human)
mRNA:decreased expression:lung (human)		 RGD PMID:7981622 PMID:29254206 RGD:151665107 RGD:151665112 NCBI chrNW_004955405:10,647,777...10,766,909
Ensembl chrNW_004955405:10,648,818...10,766,993 		JBrowse link
G Ptprj protein tyrosine phosphatase receptor type J susceptibility ISO DNA:missense mutations:cds:p.R326Q, p.Q276P (human) RGD PMID:19672627 RGD:152176665 NCBI chrNW_004955422:396,266...438,792
Ensembl chrNW_004955422:399,357...443,054 		JBrowse link
G Rac1 Rac family small GTPase 1 exacerbates
ameliorates		 ISO mRNA:increased expression:lung (human) RGD PMID:31779616 PMID:32366477 RGD:152998910 RGD:153345550 NCBI chrNW_004955460:13,270,159...13,295,562
Ensembl chrNW_004955460:13,270,159...13,311,351 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:1760348 PMID:8601312 PMID:10064593 PMID:12077328 PMID:17603482 More... NCBI chrNW_004955429:17,980,956...18,049,723
Ensembl chrNW_004955429:18,025,932...18,049,723 		JBrowse link
G Rangrf RAN guanine nucleotide release factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955467:8,622,843...8,624,401
Ensembl chrNW_004955467:8,622,843...8,624,401 		JBrowse link
G Rarb retinoic acid receptor beta ISO DNA:hypomethylation:lung RGD PMID:26695082 RGD:13464334 NCBI chrNW_004955430:17,067,536...17,457,558
Ensembl chrNW_004955430:17,295,174...17,460,045 		JBrowse link
G Rasa1 RAS p21 protein activator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chrNW_004955418:23,807,740...23,897,699
Ensembl chrNW_004955418:23,807,740...23,897,707 		JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chrNW_004955431:1,960,765...2,124,576
Ensembl chrNW_004955431:1,960,661...2,124,576 		JBrowse link
G Rbm10 RNA binding motif protein 10 ISO DNA:missense mutations, protein-truncating variants: :multiple
mRNA, protein:decreased expression:lung		 RGD PMID:22980975 PMID:29085465 PMID:30955253 RGD:11097386 RGD:151356983 RGD:151356984 NCBI chrNW_004955516:904,852...934,313
Ensembl chrNW_004955516:904,062...934,313 		JBrowse link
G Rcl1 RNA terminal phosphate cyclase like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955434:9,073,643...9,137,387
Ensembl chrNW_004955434:9,073,525...9,137,678 		JBrowse link
G Rfc4 replication factor C subunit 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955420:20,948,549...20,967,845
Ensembl chrNW_004955420:20,948,549...20,967,845 		JBrowse link
G Rin3 Ras and Rab interactor 3 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chrNW_004955438:14,777,866...14,898,572
Ensembl chrNW_004955438:14,778,262...14,898,747 		JBrowse link
G Rnaseh2a ribonuclease H2 subunit A ISO CTD Direct Evidence: marker/mechanism CTD PMID:34254728 NCBI chrNW_004955415:31,884,533...31,894,159
Ensembl chrNW_004955415:31,884,533...31,898,433 		JBrowse link
G Rnf43 ring finger protein 43 severity ISO human cells in a mouse model RGD PMID:31286874 RGD:151361222 NCBI chrNW_004955451:4,604,985...4,680,762
Ensembl chrNW_004955451:4,604,985...4,680,762 		JBrowse link
G Ros1 ROS proto-oncogene 1, receptor tyrosine kinase ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chrNW_004955436:528,038...636,194
Ensembl chrNW_004955436:524,854...636,338 		JBrowse link
G Rpl10a ribosomal protein L10a ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955437:3,383,265...3,386,064
Ensembl chrNW_004955437:3,383,265...3,386,064 		JBrowse link
G Rpl13a ribosomal protein L13a ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955559:1,358,479...1,362,663
Ensembl chrNW_004955559:1,358,486...1,362,663 		JBrowse link
G Rpl27a ribosomal protein L27a ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955414:24,461,997...24,464,828 JBrowse link
G Rpl36a ribosomal protein L36a ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955503:7,520,530...7,523,593 JBrowse link
G Rpsa ribosomal protein SA ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955420:29,978,160...29,983,544 JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955414:19,850,523...19,904,879
Ensembl chrNW_004955414:19,850,530...19,905,266 		JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955487:5,477,097...5,481,422
Ensembl chrNW_004955487:5,476,954...5,483,049 		JBrowse link
G Rrs1 ribosome biogenesis regulator 1 homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955444:12,740,172...12,751,674 JBrowse link
G Satb1 SATB homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955430:10,587,539...10,683,887
Ensembl chrNW_004955430:10,587,539...10,683,887 		JBrowse link
G Sdc1 syndecan 1 ISO mRNA:increased expression:lung (human) RGD PMID:23374247 RGD:151708716 NCBI chrNW_004955469:2,762,696...2,773,697 JBrowse link
G Serpina3 serpin family A member 3 ISO protein:increased expression:cytoplasm RGD PMID:8620411 RGD:5147446 NCBI chrNW_004955438:17,758,763...17,766,113
Ensembl chrNW_004955438:17,758,718...17,766,180 		JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase exacerbates
ameliorates
severity		 ISO DNA:mutations:multiple (human)
human cells and genes in mouse model		 RGD PMID:27687306 PMID:28202515 PMID:33223508 PMID:33707235 RGD:126848875 RGD:150429633 RGD:150429648 RGD:150429649 NCBI chrNW_004955420:25,070,626...25,178,410
Ensembl chrNW_004955420:25,090,798...25,177,760 		JBrowse link
G Sfn stratifin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chrNW_004955452:6,217,519...6,218,481
Ensembl chrNW_004955452:6,217,698...6,218,444 		JBrowse link
G Sftpc surfactant protein C ISO CTD Direct Evidence: marker/mechanism CTD PMID:25851810 NCBI chrNW_004955403:45,649,149...45,651,421
Ensembl chrNW_004955403:45,649,122...45,651,837 		JBrowse link
G Sfxn1 sideroflexin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955408:28,054,211...28,105,294
Ensembl chrNW_004955408:28,054,211...28,106,175 		JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955478:10,972,791...11,001,535
Ensembl chrNW_004955478:10,978,139...11,001,202 		JBrowse link
G Slc15a2 solute carrier family 15 member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955427:21,221,778...21,255,725
Ensembl chrNW_004955427:21,221,750...21,255,725 		JBrowse link
G Slc19a1 solute carrier family 19 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955407:42,132,216...42,154,252
Ensembl chrNW_004955407:42,132,165...42,141,992 		JBrowse link
G Slc1a5 solute carrier family 1 member 5 disease_progression ISO RGD PMID:26279756 RGD:151361150 NCBI chrNW_004955574:798,004...806,631 JBrowse link
G Slc22a18 solute carrier family 22 member 18 disease_progression ISO mRNA:increased expression:lung (human)
ClinVar Annotator: match by term: Lung adenocarcinoma		 RGD
ClinVar		 PMID:27993330 PMID:32726996 RGD:150557423 NCBI chrNW_004955422:14,590,588...14,615,898
Ensembl chrNW_004955422:14,592,250...14,616,890 		JBrowse link
G Slc3a2 solute carrier family 3 member 2 disease_progression ISO RGD PMID:19171406 RGD:151361151 NCBI chrNW_004955599:376,133...391,434
Ensembl chrNW_004955599:376,245...391,311 		JBrowse link
G Slc4a4 solute carrier family 4 member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955447:1,599,986...1,900,791
Ensembl chrNW_004955447:1,599,929...1,900,791 		JBrowse link
G Slc4a7 solute carrier family 4 member 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955430:18,991,615...19,059,590
Ensembl chrNW_004955430:18,991,301...19,067,754 		JBrowse link
G Slc7a5 solute carrier family 7 member 5 disease_progression ISO RGD PMID:19171406 PMID:26279756 RGD:151361150 RGD:151361151 NCBI chrNW_004955541:2,103,437...2,129,668
Ensembl chrNW_004955541:2,103,384...2,130,310 		JBrowse link
G Smad4 SMAD family member 4 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:6604412 PMID:8898652 PMID:9214508 PMID:9285566 PMID:9582123 More... NCBI chrNW_004955402:35,956,080...36,001,746
Ensembl chrNW_004955402:35,961,165...35,994,538 		JBrowse link
G Smarcc1 SWI/SNF related BAF chromatin remodeling complex subunit C1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955420:24,594,057...24,729,108
Ensembl chrNW_004955420:24,593,830...24,729,108 		JBrowse link
G Snrpb small nuclear ribonucleoprotein polypeptides B and B1 severity ISO mRNA:increased expression:lung (human) RGD PMID:22876301 RGD:10768834 NCBI chrNW_004955415:13,522,638...13,530,725
Ensembl chrNW_004955415:13,520,530...13,531,466 		JBrowse link
G Snrpe small nuclear ribonucleoprotein polypeptide E severity ISO mRNA:increased expression:lung (human) RGD PMID:22876301 RGD:10768834 NCBI chrNW_004955406:39,725,841...39,732,527
Ensembl chrNW_004955406:39,725,446...39,734,586 		JBrowse link
G Snrpg small nuclear ribonucleoprotein polypeptide G ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955424:14,844,318...14,851,720
Ensembl chrNW_004955424:14,844,318...14,851,720 		JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chrNW_004955439:21,209,101...21,223,538
Ensembl chrNW_004955439:21,209,101...21,224,163 		JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chrNW_004955441:6,649,895...6,724,271
Ensembl chrNW_004955441:6,646,385...6,713,028 		JBrowse link
G Sox2 SRY-box transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25184679 NCBI chrNW_004955420:10,671,888...10,674,080
Ensembl chrNW_004955420:10,671,978...10,672,934 		JBrowse link
G Sox30 SRY-box transcription factor 30 disease_progression ISO RGD PMID:26330328 RGD:11535423 NCBI chrNW_004955408:11,790,145...11,830,426
Ensembl chrNW_004955408:11,790,079...11,828,962 		JBrowse link
G Sox4 SRY-box transcription factor 4 ISO protein:increased expression:lung RGD PMID:29882245 RGD:153297792 NCBI chrNW_004955483:5,076,664...5,077,059 JBrowse link
G Spop speckle type BTB/POZ protein ameliorates ISO human gene and cell line in mouse model
mRNA, protein:increased expression:lung (human)		 RGD PMID:30607139 PMID:31105033 RGD:153298920 RGD:153298927 NCBI chrNW_004955451:11,897,642...11,970,269
Ensembl chrNW_004955451:11,897,592...11,970,269 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase severity ISO RGD PMID:12826049 RGD:150521546 NCBI chrNW_004955445:19,213,210...19,227,670
Ensembl chrNW_004955445:19,215,161...19,228,695 		JBrowse link
G Srm spermidine synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955486:2,631,579...2,634,779
Ensembl chrNW_004955486:2,631,586...2,634,527 		JBrowse link
G Srr serine racemase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955481:919,692...940,066
Ensembl chrNW_004955481:871,654...937,770 		JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 severity ISO RGD PMID:23071587 RGD:150429662 NCBI chrNW_004955451:4,992,634...4,996,619
Ensembl chrNW_004955451:4,992,634...4,999,029 		JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 severity ISO RGD PMID:23071587 RGD:150429662 NCBI chrNW_004955506:5,569,280...5,572,164
Ensembl chrNW_004955506:5,569,302...5,570,120 		JBrowse link
G Stk11 serine/threonine kinase 11 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chrNW_004955495:6,678,195...6,699,408
Ensembl chrNW_004955495:6,678,195...6,699,058 		JBrowse link
G Stk39 serine/threonine kinase 39 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955449:6,112,726...6,387,925
Ensembl chrNW_004955449:6,167,752...6,390,736 		JBrowse link
G Strbp spermatid perinuclear RNA binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955419:4,732,467...4,858,872
Ensembl chrNW_004955419:4,795,953...4,852,398 		JBrowse link
G Suclg2 succinate-CoA ligase GDP-forming subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955421:20,089,471...20,350,334
Ensembl chrNW_004955421:20,089,237...20,350,843 		JBrowse link
G Tert telomerase reverse transcriptase susceptibility ISO DNA:SNP:: rs2736100(human)
DNA:SNP::rs33963617(human)
DNA:SNPs:: rs2853669,rs2736108(human)
DNA:SNP: :rs2736098(human)		 RGD PMID:19955392 PMID:23738012 PMID:23908149 PMID:24761905 PMID:31935503 RGD:150530485 RGD:150530498 RGD:150530502 RGD:150530628 RGD:150530635 NCBI chrNW_004955504:649,248...669,796
Ensembl chrNW_004955504:651,779...670,589 		JBrowse link
G Tgfb2 transforming growth factor beta 2 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chrNW_004955406:174,949...249,248
Ensembl chrNW_004955406:172,814...249,248 		JBrowse link
G Timm10 translocase of inner mitochondrial membrane 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955511:2,498,498...2,500,828
Ensembl chrNW_004955511:2,497,307...2,500,786 		JBrowse link
G Timm8a translocase of inner mitochondrial membrane 8A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955503:7,480,075...7,483,218
Ensembl chrNW_004955503:7,480,075...7,483,218 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 ISO mRNA:decreased expression:lung (human) RGD PMID:23374247 RGD:151708716 NCBI chrNW_004955405:41,613,976...41,655,813
Ensembl chrNW_004955405:41,613,966...41,655,813 		JBrowse link
G Tk1 thymidine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955506:4,379,830...4,390,729
Ensembl chrNW_004955506:4,379,830...4,394,713 		JBrowse link
G Tlr4 toll like receptor 4 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135 		JBrowse link
G Tnfsf10 TNF superfamily member 10 ISO CTD Direct Evidence: therapeutic CTD PMID:24345465 NCBI chrNW_004955420:2,550,392...2,566,448
Ensembl chrNW_004955420:2,549,142...2,566,564 		JBrowse link
G Tomm40 translocase of outer mitochondrial membrane 40 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955555:1,987,063...1,997,329
Ensembl chrNW_004955555:1,987,261...1,996,886 		JBrowse link
G Top2a DNA topoisomerase II alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955451:14,928,273...14,964,855
Ensembl chrNW_004955451:14,929,136...14,964,723 		JBrowse link
G Tp53 tumor protein p53 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:1565144 PMID:1631137 PMID:2046748 PMID:7732013 PMID:8423216 More... NCBI chrNW_004955467:9,241,391...9,256,716
Ensembl chrNW_004955467:9,252,130...9,255,928 		JBrowse link
G Tp63 tumor protein p63 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24880342 NCBI chrNW_004955420:18,178,639...18,384,786
Ensembl chrNW_004955420:18,176,155...18,384,786 		JBrowse link
G Tpi1 triosephosphate isomerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955413:4,467,615...4,471,594
Ensembl chrNW_004955413:4,467,566...4,471,177 		JBrowse link
G Traf4 TNF receptor associated factor 4 ISO mRNA:increased expression:lung (human) RGD PMID:29254206 RGD:151665107 NCBI chrNW_004955481:4,410,906...4,417,553
Ensembl chrNW_004955481:4,410,906...4,417,061 		JBrowse link
G Ttf1 transcription termination factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25851810 NCBI chrNW_004955513:1,804,690...1,829,705 JBrowse link
G Ttr transthyretin ISO mRNA,protein:increased expression:lung (human) RGD PMID:26943652 RGD:151665207 NCBI chrNW_004955402:18,921,235...18,927,976
Ensembl chrNW_004955402:18,921,274...18,928,108 		JBrowse link
G Tyms thymidylate synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955402:9,295,862...9,304,952
Ensembl chrNW_004955402:9,296,321...9,306,631 		JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 ameliorates ISO human cell line in a mouse model RGD PMID:32867711 RGD:151665200 NCBI chrNW_004955417:26,997,572...27,085,511
Ensembl chrNW_004955417:26,998,513...27,083,005 		JBrowse link
G Uck2 uridine-cytidine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955462:10,815,496...10,925,364
Ensembl chrNW_004955462:10,815,389...10,886,227 		JBrowse link
G Vav1 vav guanine nucleotide exchange factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chrNW_004955495:2,697,508...2,755,468
Ensembl chrNW_004955495:2,695,730...2,755,824 		JBrowse link
G Wrap53 WD repeat containing antisense to TP53 severity ISO RGD PMID:28347242 RGD:21081522 NCBI chrNW_004955467:9,225,506...9,240,756 JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21327329 PMID:27777383 NCBI chrNW_004955429:16,935,901...16,968,285
Ensembl chrNW_004955429:16,935,901...16,955,845 		JBrowse link
G Xpo1 exportin 1 exacerbates ISO circRNA:increased expression:lung (human)
mRNA:increased expression:lung (human)		 RGD PMID:23639940 PMID:33268793 RGD:151665799 RGD:151665801 NCBI chrNW_004955424:22,370,006...22,420,568
Ensembl chrNW_004955424:22,370,006...22,420,568 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 severity
susceptibility		 ISO DNA:missense mutation:exon 10: p.R399Q (rs25487) (human)
DNA:missense mutation:cds: p.R399Q (human)		 RGD PMID:11104903 PMID:20003463 RGD:151347406 RGD:151347422 NCBI chrNW_004955555:1,293,416...1,315,839
Ensembl chrNW_004955555:1,293,416...1,315,839 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955453:16,967,453...17,054,634
Ensembl chrNW_004955453:16,967,453...17,054,634 		JBrowse link
G Xrcc6 X-ray repair cross complementing 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chrNW_004955413:27,135,785...27,158,344
Ensembl chrNW_004955413:27,135,805...27,159,750 		JBrowse link
G Zfhx3 zinc finger homeobox 3 ameliorates ISO DNA:mutations:multiple (human) RGD PMID:32653938 RGD:151361163 NCBI chrNW_004955484:5,470,203...5,746,325
Ensembl chrNW_004955484:5,474,769...5,789,707 		JBrowse link
bronchiolo-alveolar adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alx4 ALX homeobox 4 ameliorates ISO RGD PMID:24037716 RGD:153344522 NCBI chrNW_004955422:3,278,615...3,290,799
Ensembl chrNW_004955422:3,278,615...3,291,714 		JBrowse link
G Ccnd1 cyclin D1 ISO protein:increased expression:lung RGD PMID:14674039 RGD:13434930 NCBI chrNW_004955422:16,449,921...16,462,676
Ensembl chrNW_004955422:16,448,770...16,463,300 		JBrowse link
G Dnmt1 DNA methyltransferase 1 disease_progression ISO RGD PMID:19484794 RGD:4140940 NCBI chrNW_004955495:1,465,529...1,505,379
Ensembl chrNW_004955495:1,465,480...1,505,462 		JBrowse link
G Egfr epidermal growth factor receptor ISO DNA:mutations:exons:
protein:increased expression:tumor (human)
DNA:snp:cds:p.T790M (human)		 RGD PMID:15737014 PMID:21419590 PMID:26059825 RGD:11075076 RGD:5131465 RGD:5131630 NCBI chrNW_004955456:321,222...456,431 JBrowse link
G Egr1 early growth response 1 ISO mRNA:decreased expression:tumor (human) RGD PMID:11948124 RGD:5131942 NCBI chrNW_004955418:2,001,509...2,005,269
Ensembl chrNW_004955418:2,002,699...2,005,007 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO DNA:hypermethylation:promoter (human) RGD PMID:19484794 RGD:4140940 NCBI chrNW_004955422:17,914,228...17,916,918
Ensembl chrNW_004955422:17,914,305...17,917,428 		JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO DNA:mutations:cds: RGD PMID:26059825 RGD:11075076 NCBI chrNW_004955413:20,298,852...20,328,756
Ensembl chrNW_004955413:20,298,824...20,328,758 		JBrowse link
G Tp53 tumor protein p53 ISO DNA:mutations:exons: RGD PMID:26059825 RGD:11075076 NCBI chrNW_004955467:9,241,391...9,256,716
Ensembl chrNW_004955467:9,252,130...9,255,928 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14337
    disease of cellular proliferation 6893
      cancer 5065
        cell type cancer 3349
          carcinoma 2878
            adenocarcinoma 1483
              lung adenocarcinoma 307
                bronchiolo-alveolar adenocarcinoma + 8
                lung acinar adenocarcinoma 0
                lung clear cell carcinoma 0
                lung mucinous cystadenocarcinoma 0
                lung occult adenocarcinoma 0
                lung papillary adenocarcinoma 0
                mucinous lung adenocarcinoma 0
                pulmonary adenocarcinoma in situ 0
                signet ring lung adenocarcinoma 0
                solid adenocarcinoma with mucin production 0
Path 2
Term Annotations click to browse term
  disease 14337
    disease of anatomical entity 14030
      respiratory system disease 4555
        thoracic disease 3523
          Thoracic Neoplasms 909
            Respiratory Tract Neoplasms 907
              Lung Neoplasms 885
                Bronchial Neoplasms 612
                  bronchus cancer 612
                    bronchus carcinoma 612
                      lung non-small cell carcinoma 575
                        lung adenocarcinoma 307
                          bronchiolo-alveolar adenocarcinoma + 8
                          lung acinar adenocarcinoma 0
                          lung clear cell carcinoma 0
                          lung mucinous cystadenocarcinoma 0
                          lung occult adenocarcinoma 0
                          lung papillary adenocarcinoma 0
                          mucinous lung adenocarcinoma 0
                          pulmonary adenocarcinoma in situ 0
                          signet ring lung adenocarcinoma 0
                          solid adenocarcinoma with mucin production 0
paths to the root