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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:teratoma
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Accession:DOID:3307 term browser browse the term
Definition:A germ cell and embryonal cancer that is an encapsulated tumor with tissue or organ components resembling normal derivatives of all three germ layers. (DO)
Synonyms:exact_synonym: dysembryoma;   dysembryomas;   teratoid tumor;   teratoid tumors;   teratomas
 primary_id: MESH:D013724
 xref: ICDO:9080/3;   NCI:C3403
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
teratoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aff1 ALF transcription elongation factor 1 ISO ClinVar Annotator: match by term: Teratoma ClinVar NCBI chr14:6,165,864...6,328,848
Ensembl chr14:6,169,562...6,328,879 		JBrowse link
G Arhgef10l Rho guanine nucleotide exchange factor 10 like ISO ClinVar Annotator: match by term: Teratoma ClinVar NCBI chr 5:158,075,370...158,218,358
Ensembl chr 5:158,075,370...158,180,685 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator disease_progression ISO RGD PMID:17390059 RGD:2296025 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Chd2 chromodomain helicase DNA binding protein 2 ISO ClinVar Annotator: match by term: Teratoma ClinVar NCBI chr 1:136,597,993...136,726,874
Ensembl chr 1:136,599,900...136,710,335 		JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 ISO ClinVar Annotator: match by term: Teratoma ClinVar NCBI chr 3:98,408,240...98,449,104
Ensembl chr 3:98,408,058...98,449,104 		JBrowse link
G Crebbp CREB binding protein ISO ClinVar Annotator: match by term: Teratoma ClinVar NCBI chr10:11,842,307...11,968,266
Ensembl chr10:11,822,620...11,968,266 		JBrowse link
G Cripto cripto, EGF-CFC family member treatment ISO RGD PMID:20641036 RGD:11561895 NCBI chr 8:119,803,182...119,808,714
Ensembl chr 8:119,803,220...119,808,948 		JBrowse link
G Ctnnb1 catenin beta 1 ISO RGD PMID:16822086 RGD:2298800 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Ddx6 DEAD-box helicase 6 ISO ClinVar Annotator: match by term: Teratoma ClinVar NCBI chr 8:53,827,661...53,864,538
Ensembl chr 8:53,827,835...53,860,977 		JBrowse link
G Epas1 endothelial PAS domain protein 1 ISO ClinVar Annotator: match by term: Teratoma ClinVar NCBI chr 6:13,543,252...13,626,147
Ensembl chr 6:13,544,389...13,624,729 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 ISO ClinVar Annotator: match by term: Teratoma ClinVar NCBI chr 9:76,973,386...78,045,633
Ensembl chr 9:76,973,227...78,045,772 		JBrowse link
G Etnk1 ethanolamine kinase 1 ISO ClinVar Annotator: match by term: Teratoma ClinVar NCBI chr 4:177,857,001...177,901,278
Ensembl chr 4:177,856,960...177,924,721 		JBrowse link
G Flt4 Fms related receptor tyrosine kinase 4 ISO ClinVar Annotator: match by term: Teratoma ClinVar NCBI chr10:34,414,834...34,455,878
Ensembl chr10:34,414,733...34,456,645 		JBrowse link
G H19 H19 imprinted maternally expressed transcript ISO RGD PMID:10521301 RGD:2306183 NCBI chr 1:207,160,175...207,162,851 JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 ISO ClinVar Annotator: match by term: Teratoma ClinVar NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:143,439,323...143,467,248 		JBrowse link
G Ikzf1 IKAROS family zinc finger 1 ISO ClinVar Annotator: match by term: Teratoma ClinVar NCBI chr14:90,468,696...90,556,522
Ensembl chr14:90,469,172...90,557,574 		JBrowse link
G Kdr kinase insert domain receptor ISO ClinVar Annotator: match by term: Teratoma ClinVar NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192 		JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Teratoma ClinVar NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320 		JBrowse link
G Lats1 large tumor suppressor kinase 1 ISO ClinVar Annotator: match by term: Teratoma ClinVar NCBI chr 1:3,980,801...4,014,029
Ensembl chr 1:3,980,544...4,014,029 		JBrowse link
G Nanog Nanog homeobox severity ISO mouse gene in a rat Myocardial Infarction model;protein:decreased expression:embryonic stem cell RGD PMID:20817694 RGD:9681441 NCBI chr 4:157,615,687...157,623,061
Ensembl chr 4:157,615,687...157,623,061 		JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 ISO DNA:deletion RGD PMID:7518576 RGD:2299072 NCBI chr10:79,403,939...79,426,620
Ensembl chr10:79,403,940...79,413,310 		JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 ISO DNA:deletion RGD PMID:7518576 RGD:2299072 NCBI chr10:79,394,999...79,400,418
Ensembl chr20:11,179,066...11,179,497
Ensembl chr10:11,179,066...11,179,497 		JBrowse link
G Pabpc1 poly(A) binding protein, cytoplasmic 1 ISO ClinVar Annotator: match by term: Teratoma ClinVar NCBI chr 7:69,662,513...69,674,806
Ensembl chr 7:69,663,068...69,675,050 		JBrowse link
G Pgm1 phosphoglucomutase 1 ISO RGD PMID:5259759 RGD:2299871 NCBI chr 5:119,710,734...119,770,159
Ensembl chr 5:119,710,737...119,770,159 		JBrowse link
G Pgm3 phosphoglucomutase 3 ISO RGD PMID:5259759 RGD:2299871 NCBI chr 8:96,398,331...96,416,045
Ensembl chr 8:96,398,269...96,416,021 		JBrowse link
G Polq DNA polymerase theta ISO ClinVar Annotator: match by term: Teratoma ClinVar NCBI chr11:77,179,190...77,281,270
Ensembl chr11:77,179,209...77,281,268 		JBrowse link
G Ptprb protein tyrosine phosphatase, receptor type, B ISO RGD PMID:23575676 RGD:151660354 NCBI chr 7:53,816,197...53,920,760
Ensembl chr 7:53,816,097...53,920,760 		JBrowse link
G Rabep1 rabaptin, RAB GTPase binding effector protein 1 ISO ClinVar Annotator: match by term: Teratoma ClinVar NCBI chr10:56,064,742...56,168,778
Ensembl chr10:56,064,753...56,166,177 		JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase ISO ClinVar Annotator: match by term: Teratoma ClinVar NCBI chr 8:119,390,207...119,475,863
Ensembl chr 8:119,390,207...119,475,863 		JBrowse link
G Slc45a3 solute carrier family 45, member 3 ISO ClinVar Annotator: match by term: Teratoma ClinVar NCBI chr13:45,959,467...45,979,763
Ensembl chr13:45,959,467...45,979,763 		JBrowse link
G Snd1 staphylococcal nuclease and tudor domain containing 1 ISO ClinVar Annotator: match by term: Teratoma ClinVar NCBI chr 4:58,060,689...58,459,926
Ensembl chr 4:58,060,640...58,459,925 		JBrowse link
G Ssx1 SSX family member 1 ISO ClinVar Annotator: match by term: Teratoma ClinVar NCBI chr  X:16,603,888...16,612,203
Ensembl chr  X:16,604,449...16,612,210 		JBrowse link
G Suz12 SUZ12 polycomb repressive complex 2 subunit ISO ClinVar Annotator: match by term: Teratoma ClinVar NCBI chr10:65,464,948...65,510,846
Ensembl chr10:65,464,969...65,510,846 		JBrowse link
G Tert telomerase reverse transcriptase ISO mRNA:decreased expression RGD PMID:12168080 RGD:2298558 NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:31,466,056...31,488,111 		JBrowse link
G Trrap transformation/transcription domain-associated protein ISO ClinVar Annotator: match by term: Teratoma ClinVar PMID:25741868 NCBI chr12:14,851,758...14,941,444
Ensembl chr12:14,851,758...14,941,407 		JBrowse link
G Tymp thymidine phosphorylase ISO protein:increased expression:testis RGD PMID:10886088 RGD:2293724 NCBI chr 7:122,318,396...122,323,716
Ensembl chr 7:122,316,520...122,324,003 		JBrowse link
G Wnt2b Wnt family member 2B ISO RGD PMID:16822086 RGD:2298800 NCBI chr 2:195,142,573...195,156,945
Ensembl chr 2:195,135,176...195,157,144 		JBrowse link
atypical teratoid rhabdoid tumor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atrx ATRX, chromatin remodeler ISO ClinVar Annotator: match by term: Atypical teratoid/rhabdoid tumor ClinVar PMID:7697714 PMID:8968741 PMID:18414213 PMID:22995991 PMID:24082139 More... NCBI chr  X:74,916,548...75,062,880
Ensembl chr  X:74,916,548...75,062,880 		JBrowse link
G Gpc3 glypican 3 ISO protein:increased expression:brain (human) RGD PMID:23530909 RGD:243065128 NCBI chr  X:136,789,770...137,157,598
Ensembl chr  X:136,789,770...137,157,639 		JBrowse link
G Smarcb1 SWI/SNF related BAF chromatin remodeling complex subunit B1 ISS
ISO 		OMIM:609322
ClinVar Annotator: match by term: Teratoid tumor, atypical 		MouseDO
ClinVar		 PMID:25741868 NCBI chr20:12,740,105...12,763,054
Ensembl chr20:12,740,943...12,763,055 		JBrowse link
G Tp53 tumor protein p53 ISO ClinVar Annotator: match by term: Atypical teratoid/rhabdoid tumor ClinVar PMID:1565143 PMID:1591732 PMID:2046748 PMID:4122735 PMID:7565304 More... NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
dermoid cyst of ovary term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxo3 forkhead box O3 ISS OMIM:166950 MouseDO NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845 		JBrowse link
oculoectodermal syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cluap1 clusterin associated protein 1 ISO ClinVar Annotator: match by term: Toriello-Lacassie-Droste syndrome ClinVar PMID:26820066 NCBI chr10:12,094,346...12,159,440
Ensembl chr10:12,094,346...12,131,693 		JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Aplasia cutis congenita with epibulbar dermoids | ClinVar Annotator: match by term: OCULOECTODERMAL SYNDROME, SOMATIC | ClinVar Annotator: match by term: Toriello-Lacassie-Droste syndrome OMIM
ClinVar		 PMID:1875403 PMID:2547513 PMID:3627975 PMID:7773929 PMID:8439212 More... NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320 		JBrowse link
G Nlrp5 NLR family, pyrin domain containing 5 ISO ClinVar Annotator: match by term: Toriello-Lacassie-Droste syndrome ClinVar PMID:20738330 PMID:25326637 PMID:26323243 NCBI chr 1:76,811,044...76,872,964
Ensembl chr 1:76,810,108...77,077,580 		JBrowse link
ring dermoid of cornea term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pitx2 paired-like homeodomain 2 ISO ClinVar Annotator: match by term: Ring dermoid of cornea
CTD Direct Evidence: marker/mechanism 		OMIM
ClinVar
CTD		 PMID:15378534 PMID:15591271 PMID:21052876 PMID:22224469 PMID:22569110 More... NCBI chr 2:220,391,417...220,411,588
Ensembl chr 2:220,391,888...220,411,591 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19150
    disease of cellular proliferation 7899
      Neoplasms by Histologic Type 5351
        Germ Cell and Embryonal Neoplasms 579
          germ cell and embryonal cancer 71
            teratoma 45
              Malignant Teratocarcinosarcoma 0
              Nasopharyngeal Teratoma with Dandy Walker Diaphragmatic Hernia 0
              Sacral Agenesis Syndrome 0
              Testicular Teratoma 0
              Typical Teratoid Rhabdoid Tumor 0
              atypical teratoid rhabdoid tumor 4
              central nervous system teratoma + 0
              fallopian tube teratoma 0
              gastric teratoma + 0
              malignant teratoma + 0
              mature teratoma + 5
              mediastinum teratoma 0
              pineal region teratoma + 0
              teratoma with somatic-type malignancy 0
Path 2
Term Annotations click to browse term
  disease 19150
    disease of cellular proliferation 7899
      cancer 5731
        cell type cancer 3786
          sarcoma 280
            germ cell and embryonal cancer 71
              teratoma 45
                Malignant Teratocarcinosarcoma 0
                Nasopharyngeal Teratoma with Dandy Walker Diaphragmatic Hernia 0
                Sacral Agenesis Syndrome 0
                Testicular Teratoma 0
                Typical Teratoid Rhabdoid Tumor 0
                atypical teratoid rhabdoid tumor 4
                central nervous system teratoma + 0
                fallopian tube teratoma 0
                gastric teratoma + 0
                malignant teratoma + 0
                mature teratoma + 5
                mediastinum teratoma 0
                pineal region teratoma + 0
                teratoma with somatic-type malignancy 0
paths to the root