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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:squamous cell neoplasm
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Accession:DOID:3168 term browser browse the term
Definition:A cell type benign neoplasm composed_of epithelial cells located_in the ectodermal or endodermal cells linking body cavities. (DO)
Synonyms:exact_synonym: epidermoid cell tumor;   squamous cell neoplasms;   squamous cell tumor
 primary_id: MESH:D018307
 xref: NCI:C3792
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
squamous cell neoplasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRCA2 BRCA2 DNA repair associated EXP CTD Direct Evidence: marker/mechanism CTD PMID:24880342 NCBI chr13:32,315,077...32,400,268
Ensembl chr13:32,315,086...32,400,268 		JBrowse link
G CHEK2 checkpoint kinase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24880342 NCBI chr22:28,687,743...28,741,834
Ensembl chr22:28,687,743...28,742,422 		JBrowse link
G STRAP serine/threonine kinase receptor associated protein IDA RGD PMID:16778189 RGD:1581429 NCBI chr12:15,882,387...15,903,478
Ensembl chr12:15,882,387...15,903,478 		JBrowse link
G TP63 tumor protein p63 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23271742 NCBI chr 3:189,596,746...189,897,276
Ensembl chr 3:189,631,389...189,897,276 		JBrowse link
adenoid squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNF1A HNF1 homeobox A ISO RGD PMID:10489374 RGD:150540314 NCBI chr12:120,978,543...121,002,512
Ensembl chr12:120,978,543...121,002,512 		JBrowse link
adenosquamous gallbladder carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDR2 discoidin domain receptor tyrosine kinase 2 disease_progression IDA RGD PMID:29043607 RGD:150429712 NCBI chr 1:162,630,863...162,787,405
Ensembl chr 1:162,631,373...162,787,405 		JBrowse link
G IFITM1 interferon induced transmembrane protein 1 disease_progression IDA RGD PMID:29043607 RGD:150429712 NCBI chr11:314,040...315,272
Ensembl chr11:310,041...315,272 		JBrowse link
adenosquamous lung carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TTR transthyretin HEP protein:increased expression:lung (human) RGD PMID:26943652 RGD:151665207 NCBI chr18:31,591,877...31,598,821
Ensembl chr18:31,557,009...31,598,833 		JBrowse link
Aerodigestive Tract Squamous Cell Carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide IAGP ClinVar Annotator: match by term: Aerodigestive tract cancer, squamous cell, alcohol-related, protection against ClinVar PMID:2398055 PMID:2547609 PMID:6374651 PMID:10697413 PMID:12050823 NCBI chr 4:99,304,971...99,321,401
Ensembl chr 4:99,304,971...99,321,401 		JBrowse link
G LOC126807122 P300/CBP strongly-dependent group 1 enhancer GRCh37_chr4:100238861-100240060 IAGP ClinVar Annotator: match by term: Aerodigestive tract cancer, squamous cell, alcohol-related, protection against ClinVar PMID:2398055 PMID:2547609 PMID:6374651 PMID:10697413 PMID:12050823 NCBI chr 4:99,317,704...99,318,903 JBrowse link
anogenital venereal wart term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL20 C-C motif chemokine ligand 20 IEP protein:decreased expression:skin RGD PMID:17545018 RGD:7483603 NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564 		JBrowse link
G CD8A CD8 subunit alpha HEP mRNA:decreased expression:zone of skin (human) RGD PMID:25774455 RGD:36174028 NCBI chr 2:86,784,605...86,808,396
Ensembl chr 2:86,784,610...86,808,396 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 IEP mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965 		JBrowse link
G FOXP3 forkhead box P3 IEP mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G IFNA6 interferon alpha 6 treatment IEP RGD PMID:25774455 RGD:36174028 NCBI chr 9:21,350,318...21,350,887
Ensembl chr 9:21,350,253...21,350,956 		JBrowse link
G IL10 interleukin 10 IEP mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL12B interleukin 12B treatment IEP protein:decreased expression:peripheral blood mononuclear cells (human) RGD PMID:16114559 PMID:23754510 RGD:7829774, RGD:40400714 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G IL2 interleukin 2 IEP protein:decreased expression:peripheral blood mononuclear cells (human) RGD PMID:23754510 RGD:40400714 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL21 interleukin 21 IEP protein:decreased expression:blood serum (human) RGD PMID:31414711 RGD:127285371 NCBI chr 4:122,610,108...122,621,066
Ensembl chr 4:122,610,108...122,621,066 		JBrowse link
G IL4 interleukin 4 treatment IEP protein:increased expression:peripheral blood mononuclear cells (human) RGD PMID:16114559 PMID:23754510 RGD:7829774, RGD:40400714 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL6 interleukin 6 IEP protein:decreased expression:peripheral blood mononuclear cells (human) RGD PMID:23754510 RGD:40400714 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G KLRK1 killer cell lectin like receptor K1 IEP mRNA,protein:decreased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr12:10,372,353...10,390,041
Ensembl chr12:10,372,353...10,391,874 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 treatment HEP mRNA:increased expression:zone of skin (human) RGD PMID:25774455 RGD:36174028 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor IEP mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G NCR1 natural cytotoxicity triggering receptor 1 IEP mRNA,protein:decreased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr19:54,898,198...54,938,208
Ensembl chr19:54,906,148...54,916,140 		JBrowse link
G PDCD1 programmed cell death 1 IEP mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr 2:241,849,884...241,858,894
Ensembl chr 2:241,849,884...241,858,894 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 IEP protein:increased expression:foreskin RGD PMID:18543080 RGD:39128248 NCBI chr12:112,418,947...112,509,918
Ensembl chr12:112,418,351...112,509,918 		JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 IEP protein:increased expression:foreskin RGD PMID:18543080 RGD:39128248 NCBI chr12:6,946,577...6,961,316
Ensembl chr12:6,946,468...6,961,316 		JBrowse link
G SERPINF1 serpin family F member 1 disease_progression IEP mRNA, protein:decreased expression:skin of body (human) RGD PMID:23569025 RGD:27226706 NCBI chr17:1,762,060...1,777,565
Ensembl chr17:1,762,029...1,777,565 		JBrowse link
G TGFB1 transforming growth factor beta 1 IEP mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TLR2 toll like receptor 2 IEP mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260 		JBrowse link
G TLR3 toll like receptor 3 IEP mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,068,911...186,088,073 		JBrowse link
G TLR4 toll like receptor 4 IEP mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR7 toll like receptor 7 IEP mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr  X:12,867,072...12,890,361
Ensembl chr  X:12,867,072...12,890,361 		JBrowse link
G TLR8 toll like receptor 8 IEP mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr  X:12,906,620...12,923,169
Ensembl chr  X:12,906,620...12,923,169 		JBrowse link
G TLR9 toll like receptor 9 IEP mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
G TNF tumor necrosis factor IEP protein:increased expression:peripheral blood mononuclear cells (human) RGD PMID:23754510 RGD:40400714 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF18 TNF receptor superfamily member 18 IEP mRNA,protein:increased expression:multiple (human) RGD PMID:23754510 RGD:40400714 NCBI chr 1:1,203,508...1,206,592
Ensembl chr 1:1,203,508...1,206,592 		JBrowse link
basaloid squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTCH1 patched 1 IAGP DNA:missense mutations, nonsense mutations RGD PMID:25395299 RGD:150523793 NCBI chr 9:95,442,980...95,516,971
Ensembl chr 9:95,442,980...95,517,057 		JBrowse link
bladder squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTEN phosphatase and tensin homolog disease_progression IEP associated with schistosomiasis;protein:decreased expression:urothelium (human) RGD PMID:26916953 RGD:127285612 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
Bowen's Disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCND1 cyclin D1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29103775 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CCNE1 cyclin E1 IEP associated with Vulvar Neoplasms;mRNA:increased expression:vulva RGD PMID:17471573 RGD:2289255 NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A IEP protein:increased expression:skin: RGD PMID:10583111 RGD:8662826 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G NRF1 nuclear respiratory factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21514422 NCBI chr 7:129,611,720...129,757,076
Ensembl chr 7:129,611,720...129,757,082 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:21514422 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G TFAM transcription factor A, mitochondrial EXP CTD Direct Evidence: marker/mechanism CTD PMID:21514422 NCBI chr10:58,385,410...58,399,220
Ensembl chr10:58,385,345...58,399,220 		JBrowse link
bowenoid papulosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIRC2 baculoviral IAP repeat containing 2 IEP mRNA:increased expression:perianal skin (human) RGD PMID:20346172 RGD:152998971 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 IEP mRNA:increased expression:perianal skin (human) RGD PMID:20346172 RGD:152998971 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403 		JBrowse link
Cancer, Alopecia, Pigment Dyscrasia, Onychodystrophy, and Keratoderma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SASH1 SAM and SH3 domain containing 1 IAGP ClinVar Annotator: match by term: SASH1-related condition
ClinVar Annotator: match by term: Cancer, alopecia, pigment dyscrasia, onychodystrophy, and keratoderma		 OMIM
ClinVar		 PMID:25315659 PMID:25741868 PMID:28492532 NCBI chr 6:148,193,468...148,552,044
Ensembl chr 6:148,272,304...148,552,044 		JBrowse link
cervical squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAR adenosine deaminase RNA specific disease_progression IEP protein:increased expression:cervix squamous epithelium (human) RGD PMID:28109322 RGD:125097518 NCBI chr 1:154,582,057...154,627,997
Ensembl chr 1:154,581,695...154,628,013 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator IEP protein:increased expression:uterine cervix RGD PMID:17694953 RGD:1643352 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 disease_progression IEP DNA, protein:amplification, increased expression:uterine cervix, nucleus RGD PMID:12208731 RGD:1643529 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670 		JBrowse link
G BRIP1 BRCA1 interacting DNA helicase 1 severity IEP mRNA, protein:increased expression:uterine cervix, nucleus (human) RGD PMID:24708616 RGD:11252104 NCBI chr17:61,679,139...61,863,528
Ensembl chr17:61,679,139...61,863,559 		JBrowse link
G CCL22 C-C motif chemokine ligand 22 severity IEP RGD PMID:28086903 RGD:38455996 NCBI chr16:57,357,909...57,366,189
Ensembl chr16:57,358,783...57,366,189 		JBrowse link
G CCR4 C-C motif chemokine receptor 4 severity IEP RGD PMID:28086903 RGD:38455996 NCBI chr 3:32,951,644...32,956,349
Ensembl chr 3:32,951,644...32,957,120 		JBrowse link
G CD82 CD82 molecule IEP protein:decreased expression:uterine cervix RGD PMID:15642213 RGD:2289399 NCBI chr11:44,564,409...44,620,358
Ensembl chr11:44,564,427...44,620,363 		JBrowse link
G CSF1R colony stimulating factor 1 receptor IEP protein:increased expression:uterine cervix RGD PMID:18565574 RGD:2299119 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372 		JBrowse link
G FGF7 fibroblast growth factor 7 IEP cervical squamous cell carcinoma; mRNA:increased expression:cervical squamous cells RGD PMID:17306351 RGD:2289084 NCBI chr15:49,423,242...49,488,775
Ensembl chr15:49,423,237...49,488,775 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 no_association IAGP DNA:missense mutation:cds: p.S249G (human) RGD PMID:11605053 RGD:38500202 NCBI chr 4:1,793,293...1,808,867
Ensembl chr 4:1,793,293...1,808,872 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit disease_progression IEP protein:increased expression:uterine cervix RGD PMID:15514944 RGD:2293757 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190 		JBrowse link
G FOSL1 FOS like 1, AP-1 transcription factor subunit IEP protein:decreased expression:uterine cervix RGD PMID:15514944 RGD:2293757 NCBI chr11:65,892,049...65,900,545
Ensembl chr11:65,892,049...65,900,573 		JBrowse link
G FOXP3 forkhead box P3 severity IEP RGD PMID:28086903 RGD:38455996 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G MIR21 microRNA 21 IEP RNA:increased expression:cervical cell RGD PMID:26010154 RGD:41404529 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G MIR31 microRNA 31 IEP RNA:increased expression:blood serum (human) RGD PMID:21658006 RGD:152998938 NCBI chr 9:21,512,115...21,512,185
Ensembl chr 9:21,512,115...21,512,185 		JBrowse link
G PDPN podoplanin disease_progression IEP RGD PMID:16528371 RGD:2292237 NCBI chr 1:13,583,757...13,617,957
Ensembl chr 1:13,583,465...13,617,957 		JBrowse link
G SMAD3 SMAD family member 3 severity IEP RGD PMID:28086903 RGD:38455996 NCBI chr15:67,065,602...67,195,169
Ensembl chr15:67,063,763...67,195,173 		JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 IEP protein:decreased expression:uterine cervix RGD PMID:16619570 RGD:2290402 NCBI chr17:78,852,977...78,925,387
Ensembl chr17:78,852,977...78,925,387 		JBrowse link
G TMBIM6 transmembrane BAX inhibitor motif containing 6 disease_progression IEP mRNA:increased expression:uterine cervix RGD PMID:15337562 RGD:2291959 NCBI chr12:49,741,557...49,764,934
Ensembl chr12:49,707,725...49,764,934 		JBrowse link
G TNFRSF4 TNF receptor superfamily member 4 severity IEP RGD PMID:28086903 RGD:38455996 NCBI chr 1:1,211,340...1,214,153
Ensembl chr 1:1,211,326...1,214,153 		JBrowse link
G TNFSF4 TNF superfamily member 4 severity IEP RGD PMID:28086903 RGD:38455996 NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,162,645...173,477,583 		JBrowse link
G TP53 tumor protein p53 disease_progression IEP RGD PMID:17969407 RGD:2298526 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TYMP thymidine phosphorylase disease_progression IEP RGD PMID:16803522 RGD:2293719 NCBI chr22:50,525,752...50,530,085
Ensembl chr22:50,525,752...50,530,032 		JBrowse link
choroid plexus papilloma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TP53 tumor protein p53 IAGP
EXP		 ClinVar Annotator: match by term: Choroid plexus papilloma
ClinVar Annotator: match by term: Papilloma of choroid plexus
ClinVar Annotator: match by term: PAPILLOMA OF CHOROID PLEXUS
CTD Direct Evidence: marker/mechanism		 ClinVar
OMIM
CTD		 PMID:1565143 PMID:1565144 PMID:1591732 PMID:1631137 PMID:1683921 More... NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
conjunctival squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM3A ADAM metallopeptidase domain 3A (pseudogene) IAGP DNA, mRNA:amplification, increase expression RGD PMID:25491297 RGD:13831354 NCBI chr 8:39,451,045...39,522,989
Ensembl chr 8:39,451,045...39,522,852
Ensembl chr 8:39,451,045...39,522,852 		JBrowse link
epidermodysplasia verruciformis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC130061783 ATAC-STARR-seq lymphoblastoid active region 12855 IAGP ClinVar Annotator: match by term: Epidermodysplasia verruciformis ClinVar PMID:28492532 NCBI chr17:78,121,180...78,121,239 JBrowse link
G LOC130061785 ATAC-STARR-seq lymphoblastoid active region 12857 IAGP ClinVar Annotator: match by term: Epidermodysplasia verruciformis ClinVar PMID:25741868 PMID:28492532 NCBI chr17:78,122,490...78,122,639 JBrowse link
G LOC130061786 ATAC-STARR-seq lymphoblastoid silent region 9039 IAGP ClinVar Annotator: match by term: Epidermodysplasia verruciformis ClinVar PMID:25741868 PMID:28492532 NCBI chr17:78,124,789...78,125,038 JBrowse link
G LOC130061792 ATAC-STARR-seq lymphoblastoid silent region 9043 IAGP ClinVar Annotator: match by term: Epidermodysplasia verruciformis ClinVar PMID:9536098 PMID:12426567 PMID:17576681 PMID:22158547 PMID:25741868 More... NCBI chr17:78,131,459...78,131,978 JBrowse link
G LOC130061793 ATAC-STARR-seq lymphoblastoid silent region 9044 IAGP ClinVar Annotator: match by term: Epidermodysplasia verruciformis ClinVar PMID:12426567 PMID:22158547 PMID:28492532 NCBI chr17:78,132,089...78,132,478 JBrowse link
G LOC130061795 ATAC-STARR-seq lymphoblastoid active region 12864 IAGP ClinVar Annotator: match by term: Epidermodysplasia verruciformis ClinVar PMID:9536098 PMID:12426567 PMID:16199547 PMID:17576681 PMID:22158547 More... NCBI chr17:78,138,134...78,138,303 JBrowse link
G TMC6 transmembrane channel like 6 EXP
IAGP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Epidermodysplasia verruciformis		 CTD
ClinVar		 PMID:9536098 PMID:12426567 PMID:15042430 PMID:16199547 PMID:17139267 More... NCBI chr17:78,107,397...78,132,427
Ensembl chr17:78,107,397...78,132,407 		JBrowse link
G TMC8 transmembrane channel like 8 IAGP ClinVar Annotator: match by term: Epidermodysplasia verruciformis ClinVar PMID:9536098 PMID:10084299 PMID:12426567 PMID:16045695 PMID:16199547 More... NCBI chr17:78,130,771...78,142,968
Ensembl chr17:78,130,770...78,142,968 		JBrowse link
G TNRC6C trinucleotide repeat containing adaptor 6C IAGP ClinVar Annotator: match by term: Epidermodysplasia verruciformis ClinVar PMID:28492532 NCBI chr17:77,957,557...78,108,835
Ensembl chr17:77,958,703...78,108,822 		JBrowse link
Epidermodysplasia Verruciformis 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC130061785 ATAC-STARR-seq lymphoblastoid active region 12857 IAGP ClinVar Annotator: match by term: Epidermodysplasia verruciformis, susceptibility to, 1 ClinVar PMID:25741868 PMID:28492532 NCBI chr17:78,122,490...78,122,639 JBrowse link
G LOC130061786 ATAC-STARR-seq lymphoblastoid silent region 9039 IAGP ClinVar Annotator: match by term: TMC6-related condition ClinVar PMID:25741868 PMID:28492532 NCBI chr17:78,124,789...78,125,038 JBrowse link
G LOC130061792 ATAC-STARR-seq lymphoblastoid silent region 9043 IAGP ClinVar Annotator: match by term: Epidermodysplasia verruciformis, susceptibility to, 1 ClinVar PMID:9536098 PMID:17576681 PMID:25741868 PMID:28492532 NCBI chr17:78,131,459...78,131,978 JBrowse link
G LOC130061795 ATAC-STARR-seq lymphoblastoid active region 12864 IAGP ClinVar Annotator: match by term: Epidermodysplasia verruciformis, susceptibility to, 1 ClinVar PMID:25741868 NCBI chr17:78,138,134...78,138,303 JBrowse link
G TMC6 transmembrane channel like 6 susceptibility IAGP ClinVar Annotator: match by term: Epidermodysplasia verruciformis, susceptibility to, 1
ClinVar Annotator: match by term: Epidermodysplasia verruciformis, susceptibility to, 1 | ClinVar Annotator: match by term: TMC6-related condition		 ClinVar
OMIM		 PMID:9536098 PMID:12426567 PMID:15042430 PMID:16199547 PMID:17139267 More... NCBI chr17:78,107,397...78,132,427
Ensembl chr17:78,107,397...78,132,407 		JBrowse link
G TMC8 transmembrane channel like 8 IAGP ClinVar Annotator: match by term: Epidermodysplasia verruciformis, susceptibility to, 1 ClinVar PMID:9536098 PMID:12426567 PMID:17576681 PMID:22158547 PMID:25741868 More... NCBI chr17:78,130,771...78,142,968
Ensembl chr17:78,130,770...78,142,968 		JBrowse link
Epidermodysplasia Verruciformis 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC130061792 ATAC-STARR-seq lymphoblastoid silent region 9043 IAGP ClinVar Annotator: match by term: Epidermodysplasia verruciformis, susceptibility to, 2 ClinVar PMID:9536098 PMID:17576681 PMID:25741868 PMID:28492532 NCBI chr17:78,131,459...78,131,978 JBrowse link
G LOC130061793 ATAC-STARR-seq lymphoblastoid silent region 9044 IAGP ClinVar Annotator: match by term: TMC8-related condition ClinVar PMID:28492532 NCBI chr17:78,132,089...78,132,478 JBrowse link
G LOC130061795 ATAC-STARR-seq lymphoblastoid active region 12864 IAGP ClinVar Annotator: match by term: Epidermodysplasia verruciformis, susceptibility to, 2 ClinVar PMID:25741868 NCBI chr17:78,138,134...78,138,303 JBrowse link
G TMC6 transmembrane channel like 6 IAGP ClinVar Annotator: match by term: Epidermodysplasia verruciformis, susceptibility to, 2
ClinVar Annotator: match by term: TMC8-related condition		 ClinVar PMID:9536098 PMID:17576681 PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr17:78,107,397...78,132,427
Ensembl chr17:78,107,397...78,132,407 		JBrowse link
G TMC8 transmembrane channel like 8 susceptibility IAGP ClinVar Annotator: match by term: Epidermodysplasia verruciformis, susceptibility to, 2
ClinVar Annotator: match by term: Epidermodysplasia verruciformis, susceptibility to, 2 | ClinVar Annotator: match by term: TMC8-related condition		 ClinVar
OMIM		 PMID:9536098 PMID:10084299 PMID:12426567 PMID:16199547 PMID:17576681 More... NCBI chr17:78,130,771...78,142,968
Ensembl chr17:78,130,770...78,142,968 		JBrowse link
Epidermodysplasia Verruciformis 3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CIB1 calcium and integrin binding 1 susceptibility IAGP ClinVar Annotator: match by term: Epidermodysplasia verruciformis, susceptibility to, 3
ClinVar Annotator: match by term: CIB1-related condition		 ClinVar
OMIM		 PMID:228581 PMID:19702156 PMID:20982046 PMID:21196704 PMID:25741868 More... NCBI chr15:90,229,975...90,265,759
Ensembl chr15:90,229,975...90,234,047 		JBrowse link
G LOC130057907 ATAC-STARR-seq lymphoblastoid silent region 6817 IAGP ClinVar Annotator: match by term: Epidermodysplasia verruciformis, susceptibility to, 3 ClinVar PMID:30068544 NCBI chr15:90,233,434...90,233,883 JBrowse link
epidermolytic acanthoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KRT10 keratin 10 IAGP ClinVar Annotator: match by term: Epidermolytic acanthoma ClinVar PMID:1381287 PMID:7508181 PMID:7509230 PMID:7512983 PMID:21271994 More... NCBI chr17:40,818,117...40,822,614
Ensembl chr17:40,818,117...40,822,614 		JBrowse link
G KRT10-AS1 KRT10 antisense RNA 1 IAGP ClinVar Annotator: match by term: Epidermolytic acanthoma ClinVar PMID:1381287 PMID:7508181 PMID:7509230 PMID:7512983 PMID:21271994 More... NCBI chr17:40,819,145...40,836,274
Ensembl chr17:40,819,071...40,836,273 		JBrowse link
esophagus squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC2 ATP binding cassette subfamily C member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21206495 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ADCYAP1 adenylate cyclase activating polypeptide 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr18:904,411...912,172
Ensembl chr18:904,871...912,172 		JBrowse link
G ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide EXP CTD Direct Evidence: marker/mechanism CTD PMID:22960999 NCBI chr 4:99,304,971...99,321,401
Ensembl chr 4:99,304,971...99,321,401 		JBrowse link
G AJUBA ajuba LIM protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr14:22,971,177...22,982,551
Ensembl chr14:22,971,177...22,982,551 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 disease_progression IEP protein:increased expression:esophagus (human) RGD PMID:32642408 RGD:152995512 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member EXP CTD Direct Evidence: marker/mechanism CTD PMID:16639733 PMID:22960999 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532 		JBrowse link
G ANXA1 annexin A1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,629 		JBrowse link
G ATM ATM serine/threonine kinase disease_progression IEP Smoke Inhalation Injury; mRNA:increased expression:esophagus (human) RGD PMID:17019709 RGD:150340713 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25129146 NCBI chr17:7,646,627...7,657,770
Ensembl chr17:7,646,627...7,657,770 		JBrowse link
G AXIN1 axin 1 disease_progression IEP protein:decreased expression:esophagus (human) RGD PMID:12771989 RGD:150530473 NCBI chr16:287,440...352,723
Ensembl chr16:287,440...352,723 		JBrowse link
G AZGP1 alpha-2-glycoprotein 1, zinc-binding disease_progression IEP RGD PMID:28053542 RGD:153350138 NCBI chr 7:99,966,730...99,976,031
Ensembl chr 7:99,966,720...99,976,042 		JBrowse link
G AZIN1 antizyme inhibitor 1 IMP RGD PMID:24302582 RGD:14700707 NCBI chr 8:102,826,302...102,864,200
Ensembl chr 8:102,826,111...102,893,864 		JBrowse link
G B2M beta-2-microglobulin EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr15:44,711,517...44,718,145
Ensembl chr15:44,711,358...44,718,851 		JBrowse link
G BLVRB biliverdin reductase B EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr19:40,447,768...40,465,745
Ensembl chr19:40,447,765...40,465,764 		JBrowse link
G BMI1 BMI1 proto-oncogene, polycomb ring finger IEP RGD PMID:21165554 RGD:126781701 NCBI chr10:22,321,099...22,331,706
Ensembl chr10:22,321,099...22,331,484 		JBrowse link
G BMP6 bone morphogenetic protein 6 IEP protein:increased expression:esophagus RGD PMID:22364398 RGD:7242413 NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728 		JBrowse link
G BRCA1 BRCA1 DNA repair associated IAGP DNA:SNP: :rs799917 (human) RGD PMID:23749772 RGD:126925960 NCBI chr17:43,044,295...43,170,327
Ensembl chr17:43,044,295...43,170,245 		JBrowse link
G BRCA2 BRCA2 DNA repair associated IAGP DNA:nonsense mutation: :p.K3326X (human) RGD PMID:21279724 RGD:11344913 NCBI chr13:32,315,077...32,400,268
Ensembl chr13:32,315,086...32,400,268 		JBrowse link
G BST2 bone marrow stromal cell antigen 2 disease_progression IEP RGD PMID:26832883 RGD:14398496 NCBI chr19:17,402,939...17,405,630
Ensembl chr19:17,402,939...17,405,630 		JBrowse link
G BUB1B BUB1 mitotic checkpoint serine/threonine kinase B EXP CTD Direct Evidence: marker/mechanism CTD PMID:18691855 NCBI chr15:40,161,069...40,221,123
Ensembl chr15:40,161,023...40,221,123 		JBrowse link
G CA1 carbonic anhydrase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 8:85,327,608...85,378,113
Ensembl chr 8:85,327,608...85,379,014 		JBrowse link
G CA12 carbonic anhydrase 12 severity IEP RGD PMID:26316888 RGD:155226859 NCBI chr15:63,321,378...63,381,846
Ensembl chr15:63,321,378...63,381,846 		JBrowse link
G CA2 carbonic anhydrase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 8:85,464,007...85,481,493
Ensembl chr 8:85,463,968...85,481,493 		JBrowse link
G CALR calreticulin ameliorates EXP
IMP		 CTD Direct Evidence: marker/mechanism
human cells in a mouse model		 CTD
RGD		 PMID:21517111 PMID:19684620 PMID:23814025 RGD:150521703, RGD:150521679 NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489 		JBrowse link
G CAPZA1 capping actin protein of muscle Z-line subunit alpha 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 1:112,619,832...112,671,616
Ensembl chr 1:112,619,805...112,671,616 		JBrowse link
G CASP8 caspase 8 exacerbates IEP mRNA,protein:decreased expression:esophagus squamous epithelium (human) RGD PMID:31885720 RGD:153300949 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CBX8 chromobox 8 severity IEP mRNA:increased expression:esophagus: RGD PMID:25197352 RGD:9587436 NCBI chr17:79,792,132...79,797,077
Ensembl chr17:79,792,132...79,801,683 		JBrowse link
G CCHCR1 coiled-coil alpha-helical rod protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chr 6:31,142,439...31,158,197
Ensembl chr 6:31,142,439...31,158,238 		JBrowse link
G CCND1 cyclin D1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A EXP CTD Direct Evidence: therapeutic CTD PMID:15375580 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A EXP CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301 		JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B IAGP DNA:SNPs: :rs615552, rs573687 (human) RGD PMID:23361049 RGD:7248756 NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305 		JBrowse link
G CFL1 cofilin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026 		JBrowse link
G CHRNA5 cholinergic receptor nicotinic alpha 5 subunit susceptibility IAGP
IEP		 DNA:SNP: :rs667282(human)
mRNA:increased expression:esophagus (human)		 RGD PMID:23844051 PMID:27610024 RGD:150524358, RGD:151361143 NCBI chr15:78,565,520...78,595,269
Ensembl chr15:78,565,520...78,595,269 		JBrowse link
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit exacerbates
disease_progression		 IEP
IDA		 mRNA:increased expression:esophagus (human) RGD PMID:27610024 PMID:33603170 PMID:33603170 RGD:151361143, RGD:151667905, RGD:151667905 NCBI chr15:32,030,483...32,173,018
Ensembl chr15:31,923,438...32,173,018 		JBrowse link
G CHRNB4 cholinergic receptor nicotinic beta 4 subunit IEP mRNA:increased expression:esophagus (human) RGD PMID:27610024 RGD:151361143 NCBI chr15:78,624,111...78,661,641
Ensembl chr15:78,624,111...78,727,754 		JBrowse link
G CLIC1 chloride intracellular channel 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 6:31,730,581...31,737,318
Ensembl chr 6:31,730,581...31,739,763 		JBrowse link
G CLPTM1L CLPTM1 like susceptibility
no_association		 IAGP
IEP		 DNA:SNP: :rs451360(human)
DNA:SNP: :rs401681(human)
mRNA:increased expression:esophagus		 RGD PMID:26716642 PMID:24386361 PMID:25480402 PMID:25007268 RGD:11572962, RGD:150537098, RGD:150530497, RGD:150530488 NCBI chr 5:1,317,752...1,345,099
Ensembl chr 5:1,317,752...1,345,099 		JBrowse link
G COL14A1 collagen type XIV alpha 1 chain disease_progression IDA DNA:hypermethylation RGD PMID:25050929 RGD:151665741 NCBI chr 8:120,124,454...120,373,573
Ensembl chr 8:120,059,780...120,373,573 		JBrowse link
G CRABP1 cellular retinoic acid binding protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17438526 NCBI chr15:78,340,353...78,348,225
Ensembl chr15:78,340,353...78,348,225 		JBrowse link
G CREBBP CREB binding protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713 		JBrowse link
G CSF1R colony stimulating factor 1 receptor HEP mRNA:decreased expression:esophagus squamous epithelium (human) RGD PMID:32038997 RGD:150524298 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372 		JBrowse link
G CSTB cystatin B EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr21:43,773,950...43,776,308
Ensembl chr21:43,772,511...43,776,330 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 severity IEP mRNA:increased expression:esophagus (human) RGD PMID:31423201 RGD:150520019 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 disease_progression IEP protein:increased expression:esophagus squamous epithelium (human) RGD PMID:17171785 RGD:152023646 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 IAGP RGD PMID:11860825 RGD:14700943 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 ISO protein:increased expression:esophagus (rat) RGD PMID:18618592 RGD:7829715 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 susceptibility IAGP DNA:SNP:CDS: (rs2296241) (human) RGD PMID:28362172 RGD:151665500 NCBI chr20:54,143,538...54,173,986
Ensembl chr20:54,153,446...54,173,986 		JBrowse link
G CYP26B1 cytochrome P450 family 26 subfamily B member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chr 2:72,129,238...72,147,862
Ensembl chr 2:72,129,238...72,147,862 		JBrowse link
G CYP2A6 cytochrome P450 family 2 subfamily A member 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:11241319 NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447 		JBrowse link
G DAB2IP DAB2 interacting protein severity IEP protein:decreased expression:esophagus (human) RGD PMID:30464518 RGD:151665168 NCBI chr 9:121,567,074...121,785,530
Ensembl chr 9:121,567,057...121,785,530 		JBrowse link
G DCC DCC netrin 1 receptor IAGP DNA:deletions:multiple (human) OMIM
RGD		 PMID:8187090 RGD:734879 NCBI chr18:52,340,197...53,535,899
Ensembl chr18:52,340,197...53,535,899 		JBrowse link
G DIDO1 death inducer-obliterator 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30431698 NCBI chr20:62,877,743...62,937,904
Ensembl chr20:62,877,738...62,937,952 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta disease_progression IEP protein:increased expression:nucleus: RGD PMID:22213175 RGD:9589085 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359 		JBrowse link
G DPP4 dipeptidyl peptidase 4 IEP protein:increased expression: esophagus RGD PMID:24789592 RGD:152600903 NCBI chr 2:161,992,245...162,074,215
Ensembl chr 2:161,992,245...162,074,394 		JBrowse link
G EFNB2 ephrin B2 severity
exacerbates
ameliorates		 IEP
IMP		 mRNA:increased expression:esophagus squamous epithelium (human)
mRNA,protein:increased expression:esophagus squamous epithelium (human)
human cells in mouse model		 RGD PMID:17611172 PMID:31885720 PMID:29190834 RGD:153300947, RGD:153300949, RGD:153300948 NCBI chr13:106,489,745...106,535,662
Ensembl chr13:106,489,745...106,535,662 		JBrowse link
G EGFR epidermal growth factor receptor severity IEP
EXP		 protein:increased expression:esophagus (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:21947696 PMID:10385363 RGD:5131486 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EHMT1 euchromatic histone lysine methyltransferase 1 disease_progression IEP protein:increased expression:esophagus:
protein:increased expression:esophagus mucosa:		 RGD PMID:24649311 PMID:24805087 RGD:9589143, RGD:9590071 NCBI chr 9:137,619,005...137,836,127
Ensembl chr 9:137,618,992...137,870,016 		JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 disease_progression IEP protein:increased expression:esophagus mucosa: RGD PMID:24805087 RGD:9590071 NCBI chr 6:31,879,759...31,897,698
Ensembl chr 6:31,879,759...31,897,698 		JBrowse link
G EP300 E1A binding protein p300 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17965222 PMID:25151357 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,510...41,180,077 		JBrowse link
G EPB41L3 erythrocyte membrane protein band 4.1 like 3 disease_progression IDA DNA:hypermethylation RGD PMID:25050929 RGD:151665741 NCBI chr18:5,392,386...5,630,663
Ensembl chr18:5,392,381...5,630,700 		JBrowse link
G EPHB4 EPH receptor B4 exacerbates IEP mRNA,protein:increased expression:esophagus squamous epithelium (human) RGD PMID:31885720 RGD:153300949 NCBI chr 7:100,802,565...100,827,523
Ensembl chr 7:100,802,565...100,827,523 		JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 susceptibility
disease_progression		 IAGP
IEP		 DNA:SNPs, haplotypes: :rs1595066 and rs16845990 (human)
protein:altered localization:nucleus		 RGD PMID:24916311 PMID:18000820 RGD:126781764, RGD:126781765 NCBI chr 2:211,375,717...212,538,802
Ensembl chr 2:211,375,717...212,538,841 		JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit treatment IEP RGD PMID:23263828 RGD:11252162 NCBI chr19:45,407,334...45,451,547
Ensembl chr19:45,407,334...45,478,828 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit disease_progression IEP RGD PMID:25613619 PMID:21165554 RGD:126781697, RGD:126781701 NCBI chr 7:148,807,383...148,884,291
Ensembl chr 7:148,807,257...148,884,321 		JBrowse link
G FANCA FA complementation group A IAGP DNA:missense mutation: :p.S858R (human) RGD PMID:21279724 RGD:11344913 NCBI chr16:89,737,549...89,816,647
Ensembl chr16:89,726,683...89,816,977 		JBrowse link
G FAP fibroblast activation protein alpha IEP protein:increased expression: esophagus RGD PMID:24789592 RGD:152600903 NCBI chr 2:162,170,684...162,243,445
Ensembl chr 2:162,170,684...162,245,151 		JBrowse link
G FASN fatty acid synthase EXP CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294 		JBrowse link
G FAT1 FAT atypical cadherin 1 EXP
IEP
IMP
HEP		 CTD Direct Evidence: marker/mechanism
protein:decreased expression:esophagus squamous epithelium (human)
protein:decreased expression:esophagus squamous epithelium (human)		 CTD
RGD		 PMID:25151357 PMID:29365412 PMID:24590895 PMID:24590895 RGD:151347646, RGD:151347630, RGD:151347630 NCBI chr 4:186,587,794...186,726,696
Ensembl chr 4:186,587,794...186,726,722 		JBrowse link
G FAT2 FAT atypical cadherin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 5:151,504,092...151,594,819
Ensembl chr 5:151,504,092...151,591,331 		JBrowse link
G FAT3 FAT atypical cadherin 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr11:92,224,818...92,896,473
Ensembl chr11:92,224,818...92,896,473 		JBrowse link
G FAT4 FAT atypical cadherin 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 4:125,314,955...125,492,932
Ensembl chr 4:125,314,918...125,492,932 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 4:152,320,544...152,536,092
Ensembl chr 4:152,320,544...152,536,092 		JBrowse link
G FES FES proto-oncogene, tyrosine kinase exacerbates IDA DNA:hypermethylation: (human) RGD PMID:24936140 RGD:153323298 NCBI chr15:90,884,504...90,895,776
Ensembl chr15:90,883,695...90,895,776 		JBrowse link
G FGFR4 fibroblast growth factor receptor 4 treatment IAGP RGD PMID:25989802 RGD:150520041 NCBI chr 5:177,086,915...177,098,144
Ensembl chr 5:177,086,905...177,098,144 		JBrowse link
G FKBP1A FKBP prolyl isomerase 1A EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr20:1,368,978...1,393,054
Ensembl chr20:1,368,977...1,393,164 		JBrowse link
G FOXA1 forkhead box A1 onset IAGP
IEP		 DNA:SNPs: :rs12894364 C>T, rs2145146 C>A (human) RGD PMID:27050876 PMID:29788741 RGD:151665743, RGD:151665759 NCBI chr14:37,589,552...37,595,249
Ensembl chr14:37,589,552...37,596,059 		JBrowse link
G FUBP1 far upstream element binding protein 1 exacerbates IEP protein:increased expression:esophagus (human)
mRNA:increased expression:esophagus (human)		 RGD PMID:26490982 PMID:32481602 RGD:151361192, RGD:151361197 NCBI chr 1:77,944,055...77,979,501
Ensembl chr 1:77,944,055...77,979,110 		JBrowse link
G GDI2 GDP dissociation inhibitor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr10:5,765,223...5,813,434
Ensembl chr10:5,765,222...5,842,132 		JBrowse link
G GLO1 glyoxalase I EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 6:38,675,925...38,703,145
Ensembl chr 6:38,675,925...38,703,145 		JBrowse link
G GPX3 glutathione peroxidase 3 disease_progression IDA
HDA		 DNA:hypermethylation RGD PMID:30018730 PMID:25050929 PMID:20725785 RGD:151665494, RGD:151665741, RGD:151665495 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988 		JBrowse link
G GRB7 growth factor receptor bound protein 7 exacerbates IEP
HEP		 protein:increased expression:esophagus (human)
mRNA:increased expression:esophagus mucosa (human)		 RGD PMID:10797316 PMID:26465158 RGD:151347654, RGD:151347661 NCBI chr17:39,737,938...39,747,285
Ensembl chr17:39,737,927...39,747,291 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 no_association IAGP RGD PMID:11860825 PMID:17916905 PMID:25432134 RGD:14700943, RGD:14700982, RGD:14700948 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G GSTO1 glutathione S-transferase omega 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr10:104,254,173...104,267,455
Ensembl chr10:104,235,356...104,267,459 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 IAGP DNA:polymorphism: :p.I105V (human) RGD PMID:17916905 RGD:14700982 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G GSTT1 glutathione S-transferase theta 1 IAGP
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17173682 PMID:25432134 PMID:17916905 RGD:14700948, RGD:14700982
G H19 H19 imprinted maternally expressed transcript EXP CTD Direct Evidence: marker/mechanism CTD PMID:32739445 NCBI chr11:1,995,176...2,001,266
Ensembl chr11:1,995,165...2,004,552 		JBrowse link
G H2BC14 H2B clustered histone 14 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 6:27,815,022...27,815,489
Ensembl chr 6:27,815,022...27,815,489 		JBrowse link
G HEIH hepatocellular carcinoma up-regulated EZH2-associated long non-coding RNA exacerbates IEP mRNA:increased expression:esophagus squamous epithelium (human) RGD PMID:32449803 RGD:153345544 NCBI chr 5:180,829,954...180,831,618
Ensembl chr 5:180,824,604...180,861,858 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:17201171 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HMGB1 high mobility group box 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G HMGN5 high mobility group nucleosome binding domain 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28914995 NCBI chr  X:81,113,699...81,201,913
Ensembl chr  X:81,113,699...81,201,913 		JBrowse link
G HOXB7 homeobox B7 severity IEP protein:increased expression:esophageal mucosa (human) RGD PMID:26076456 RGD:10402177 NCBI chr17:48,607,232...48,611,017
Ensembl chr17:48,607,232...48,633,572 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G HTRA1 HtrA serine peptidase 1 exacerbates
ameliorates		 IEP
IMP		 mRNA,protein:decreased expression:epithelium of esophagus (human)
human gene and cells in mouse model		 RGD PMID:23079781 PMID:23079781 RGD:152975633, RGD:152975633 NCBI chr10:122,461,553...122,514,907
Ensembl chr10:122,458,551...122,514,907 		JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 severity IMP human cells in mouse model RGD PMID:32367071 RGD:149735568 NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,477 		JBrowse link
G JAK2 Janus kinase 2 severity IEP protein:increased phosphorylation:esophagus squamous epithelium (human) RGD PMID:32158193 RGD:127285669 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948 		JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit exacerbates IEP protein:increased expression:esophagus (human) RGD PMID:30227324 PMID:19758438 RGD:151347669, RGD:151347672 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315 		JBrowse link
G KAT2B lysine acetyltransferase 2B IEP mRNA:decreased expression:esophagus (human) RGD PMID:19525977 RGD:9590307 NCBI chr 3:20,040,446...20,154,404
Ensembl chr 3:20,040,446...20,154,404 		JBrowse link
G KDM4C lysine demethylase 4C severity
susceptibility		 IEP
IAGP		 protein:increased expression:esophageal epithelium, nucleus (human)
DNA:snp:intron:IVS8-3292G>A (rs1340513) (human)		 RGD PMID:24224128 PMID:15805246 RGD:9587746, RGD:9587752 NCBI chr 9:6,720,863...7,175,648
Ensembl chr 9:6,720,863...7,175,648 		JBrowse link
G KDM5B lysine demethylase 5B severity IEP protein:increased expression:esophageal mucosa, cytoplasm (human) RGD PMID:22534467 RGD:9587776 NCBI chr 1:202,724,495...202,808,421
Ensembl chr 1:202,724,495...202,808,487 		JBrowse link
G KDM6A lysine demethylase 6A ameliorates IAGP
IEP
EXP		 DNA:mutations:multiple (human)
mRNA:increased expression:esophagus (human)
protein:increased expression:esophagus (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:25151357 PMID:25151357 PMID:31804468 PMID:29351209 RGD:9588233, RGD:150429742, RGD:150429739 NCBI chr  X:44,873,188...45,112,779
Ensembl chr  X:44,873,188...45,112,779 		JBrowse link
G KMT2C lysine methyltransferase 2C IAGP
EXP		 DNA:mutations:multiple (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:25151357 PMID:25151357 RGD:9588233 NCBI chr 7:152,134,925...152,436,003
Ensembl chr 7:152,134,922...152,436,644 		JBrowse link
G KMT2D lysine methyltransferase 2D IAGP
IEP
EXP		 DNA:mutations:multiple (human)
mRNA:increased expression:esophagus
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:25151357 PMID:25151357 PMID:29532228 RGD:9588233, RGD:150521712 NCBI chr12:49,018,978...49,060,794
Ensembl chr12:49,018,975...49,060,794 		JBrowse link
G KRT13 keratin 13 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr17:41,500,981...41,505,612
Ensembl chr17:41,500,981...41,505,705 		JBrowse link
G KRT14 keratin 14 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16543248 NCBI chr17:41,582,279...41,586,895
Ensembl chr17:41,582,279...41,586,895 		JBrowse link
G KRT16 keratin 16 ISO RGD PMID:8950218 RGD:633113 NCBI chr17:41,609,778...41,612,767
Ensembl chr17:41,609,778...41,615,899 		JBrowse link
G KRT17 keratin 17 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr17:41,619,442...41,624,575
Ensembl chr17:41,619,442...41,624,842 		JBrowse link
G KRT19 keratin 19 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr17:41,523,617...41,528,308
Ensembl chr17:41,523,617...41,528,308 		JBrowse link
G KRT7 keratin 7 disease_progression IEP RGD PMID:29788741 RGD:151665759 NCBI chr12:52,233,243...52,255,853
Ensembl chr12:52,232,520...52,252,186 		JBrowse link
G LOXL2 lysyl oxidase like 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24716982 NCBI chr 8:23,296,897...23,404,120
Ensembl chr 8:23,296,897...23,425,328 		JBrowse link
G LTA lymphotoxin alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chr 6:31,560,610...31,574,324
Ensembl chr 6:31,572,054...31,574,324 		JBrowse link
G LZTS1 leucine zipper tumor suppressor 1 IAGP ClinVar Annotator: match by term: LZTS1-related condition
ClinVar Annotator: match by term: Esophageal squamous cell carcinoma, somatic		 OMIM
ClinVar		 PMID:10097140 PMID:25741868 PMID:26504261 PMID:28492532 NCBI chr 8:20,246,165...20,303,963
Ensembl chr 8:20,246,165...20,303,963 		JBrowse link
G MAD2L1 mitotic arrest deficient 2 like 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18691855 NCBI chr 4:120,055,623...120,066,848
Ensembl chr 4:120,055,623...120,066,858 		JBrowse link
G MALAT1 metastasis associated lung adenocarcinoma transcript 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25538231 NCBI chr11:65,497,738...65,506,516
Ensembl chr11:65,497,606...65,508,073 		JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 sexual_dimorphism IAGP DNA:missense mutation, SNP:CDS, exon 14, 3'-UTR: (rs702689,rs702688) (human) RGD PMID:32753933 RGD:150573717 NCBI chr 5:56,815,549...56,896,152
Ensembl chr 5:56,815,549...56,896,152 		JBrowse link
G MBD4 methyl-CpG binding domain 4, DNA glycosylase susceptibility IAGP DNA:snp:cds:p.E346K (rs140693) (human)
DNA:snp:intron:IVS5-140A>G (rs3138355) (human)		 RGD PMID:15205355 PMID:25162968 RGD:9588976, RGD:9588980 NCBI chr 3:129,430,947...129,439,948
Ensembl chr 3:129,430,947...129,440,179 		JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase disease_progression EXP
IDA		 CTD Direct Evidence: marker/mechanism
DNA, protein:hypermethylation, decreased expression:promoter, esophagus		 CTD
RGD		 PMID:25520135 PMID:21674174 RGD:126790574 NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983 		JBrowse link
G MIR10A microRNA 10a IEP miRNA:increased expression:esophagus squamous epithelium (human) RGD PMID:32997362 RGD:153323343 NCBI chr17:48,579,838...48,579,947
Ensembl chr17:48,579,838...48,579,947 		JBrowse link
G MIR127 microRNA 127 IEP RNA:decreased expression:esophagus (human) RGD PMID:27645894 RGD:152995354 NCBI chr14:100,882,979...100,883,075
Ensembl chr14:100,882,979...100,883,075 		JBrowse link
G MIR193A microRNA 193a exacerbates IEP miRNA:decreased expression:esophagus (human) RGD PMID:27203740 RGD:153323341 NCBI chr17:31,559,996...31,560,083
Ensembl chr17:31,559,996...31,560,083 		JBrowse link
G MIR217 microRNA 217 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25538231 NCBI chr 2:55,982,967...55,983,076
Ensembl chr 2:55,982,967...55,983,076 		JBrowse link
G MIR31 microRNA 31 ameliorates ISO
IEP		 RGD PMID:32123074 PMID:21658006 RGD:127285381, RGD:152998938 NCBI chr 9:21,512,115...21,512,185
Ensembl chr 9:21,512,115...21,512,185 		JBrowse link
G MIR31HG MIR31 host gene disease_progression IEP RNA:increased expression:blood plasma, esophagus squamous epithelium (human) RGD PMID:29605445 RGD:153297774 NCBI chr 9:21,454,268...21,559,798
Ensembl chr 9:21,364,605...21,591,906 		JBrowse link
G MIR423 microRNA 423 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24205249 NCBI chr17:30,117,079...30,117,172
Ensembl chr17:30,117,079...30,117,172 		JBrowse link
G MIR432 microRNA 432 IEP mRNA:increased expression:esophagus (human) RGD PMID:28760781 RGD:153002560 NCBI chr14:100,884,483...100,884,576
Ensembl chr14:100,884,483...100,884,576 		JBrowse link
G MIR4458 microRNA 4458 IEP RNA:decreased expression:esophagus squamous epithelium (human) RGD PMID:32449803 RGD:153345544 NCBI chr 5:8,460,925...8,460,999
Ensembl chr 5:8,460,925...8,460,999 		JBrowse link
G MIR494 microRNA 494 IEP mRNA:decreased expression:esophagus RGD PMID:25480402 RGD:150530497 NCBI chr14:101,029,634...101,029,714
Ensembl chr14:101,029,634...101,029,714 		JBrowse link
G MLH1 mutL homolog 1 disease_progression IDA DNA, protein:hypermethylation, decreased expression:promoter, esophagus RGD PMID:21674174 RGD:126790574 NCBI chr 3:36,993,466...37,050,846
Ensembl chr 3:36,993,226...37,050,896 		JBrowse link
G MMP14 matrix metallopeptidase 14 IEP protein:increased expression: esophagus RGD PMID:24789592 RGD:152600903 NCBI chr14:22,836,585...22,847,758
Ensembl chr14:22,836,560...22,849,041 		JBrowse link
G MMP2 matrix metallopeptidase 2 IEP protein:increased activity: esophagus RGD PMID:24789592 RGD:152600903 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP9 matrix metallopeptidase 9 IEP protein:increased activity: esophagus RGD PMID:24789592 RGD:152600903 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MSH2 mutS homolog 2 disease_progression IDA DNA, protein:hypermethylation, decreased expression:promoter, esophagus
DNA, protein:hypermethylation, decreased expression:esophagus		 RGD PMID:22265839 PMID:21674174 PMID:24366688 RGD:126790560, RGD:126790574, RGD:126790573 NCBI chr 2:47,403,067...47,709,830
Ensembl chr 2:47,403,067...47,663,146 		JBrowse link
G MT1X metallothionein 1X ISO CTD Direct Evidence: marker/mechanism CTD PMID:16543248 NCBI chr16:56,682,470...56,684,196
Ensembl chr16:56,682,470...56,684,196 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NOTCH1 notch receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048 		JBrowse link
G NOTCH2 notch receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 1:119,911,553...120,069,662
Ensembl chr 1:119,911,553...120,100,779 		JBrowse link
G NOTCH3 notch receptor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr19:15,159,038...15,200,995
Ensembl chr19:15,159,038...15,200,995 		JBrowse link
G OGG1 8-oxoguanine DNA glycosylase EXP CTD Direct Evidence: marker/mechanism CTD PMID:38467300 NCBI chr 3:9,749,952...9,783,108
Ensembl chr 3:9,749,944...9,788,219 		JBrowse link
G PAGR1 PAXIP1 associated glutamate rich protein 1 IEP mRNA, protein:decreased expression:esophagus (human) RGD PMID:33833989 RGD:153344568 NCBI chr16:29,816,152...29,822,489
Ensembl chr16:29,816,152...29,822,489 		JBrowse link
G PBX3 PBX homeobox 3 IEP RNA:increased expression:esophagus squamous epithelium (human) RGD PMID:32449803 RGD:153345544 NCBI chr 9:125,747,373...125,967,377
Ensembl chr 9:125,747,345...125,967,377 		JBrowse link
G PFN1 profilin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr17:4,945,652...4,948,530
Ensembl chr17:4,945,652...4,949,061 		JBrowse link
G PLCE1 phospholipase C epsilon 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20729852 PMID:20729853 NCBI chr10:93,993,931...94,332,823
Ensembl chr10:93,993,931...94,332,823 		JBrowse link
G PRDX1 peroxiredoxin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,510,914...45,542,732 		JBrowse link
G PSMB9 proteasome 20S subunit beta 9 disease_progression IEP RGD PMID:19492245 RGD:6482249 NCBI chr 6:32,854,192...32,859,851
Ensembl chr 6:32,844,136...32,860,734 		JBrowse link
G PSME1 proteasome activator subunit 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr14:24,136,194...24,138,962
Ensembl chr14:24,136,163...24,138,967 		JBrowse link
G PSME2 proteasome activator subunit 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr14:24,143,365...24,146,610
Ensembl chr14:24,143,362...24,147,570 		JBrowse link
G PTCH1 patched 1 disease_progression IEP RGD PMID:16475698 RGD:150523841 NCBI chr 9:95,442,980...95,516,971
Ensembl chr 9:95,442,980...95,517,057 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15756444 PMID:16543248 PMID:18197933 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTPRT protein tyrosine phosphatase receptor type T susceptibility IAGP DNA:SNPs:3'utr: (rs2866943 , rs6029959 ) (human) RGD PMID:25967969 RGD:150520191 NCBI chr20:42,031,890...43,189,906
Ensembl chr20:42,072,752...43,189,970 		JBrowse link
G RB1 RB transcriptional corepressor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436 		JBrowse link
G RICTOR RPTOR independent companion of MTOR complex 2 disease_progression
severity		 IMP
IEP		 human cells in mouse model
protein:increased expression:esophagus (human)		 RGD PMID:30119206 PMID:32642408 PMID:28132115 RGD:152995460, RGD:152995512, RGD:152995470 NCBI chr 5:38,937,920...39,074,399
Ensembl chr 5:38,937,920...39,074,402 		JBrowse link
G RNF6 ring finger protein 6 IAGP ClinVar Annotator: match by term: Esophageal squamous cell carcinoma, somatic OMIM
ClinVar		 PMID:12154016 NCBI chr13:26,132,115...26,223,085
Ensembl chr13:26,132,115...26,222,314 		JBrowse link
G RUNX1 RUNX family transcription factor 1 IAGP DNA:SNP: :rs2014300 (human) RGD PMID:30666517 RGD:126775149 NCBI chr21:34,787,801...35,049,302
Ensembl chr21:34,787,801...36,004,667 		JBrowse link
G RUNX2 RUNX family transcription factor 2 IEP mRNA:increased expression:esophagus mucosa RGD PMID:18500170 RGD:126779568 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349 		JBrowse link
G RUNX3 RUNX family transcription factor 3 disease_progression IEP mRNA:decreased expression:esophagus mucosa RGD PMID:18500170 RGD:126779568 NCBI chr 1:24,899,511...24,965,138
Ensembl chr 1:24,899,511...24,965,121 		JBrowse link
G SALL4 spalt like transcription factor 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30431698 NCBI chr20:51,782,331...51,802,521
Ensembl chr20:51,782,331...51,802,521 		JBrowse link
G SERPINB3 serpin family B member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr18:63,655,197...63,661,893
Ensembl chr18:63,655,197...63,661,893 		JBrowse link
G SETD5 SET domain containing 5 disease_progression IEP RGD PMID:31981592 RGD:155804254 NCBI chr 3:9,397,615...9,478,154
Ensembl chr 3:9,397,615...9,479,240 		JBrowse link
G SFN stratifin EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 1:26,863,149...26,864,456
Ensembl chr 1:26,863,149...26,864,456 		JBrowse link
G SLC16A10 solute carrier family 16 member 10 IEP protein:increased expression:esophagus RGD PMID:33609949 RGD:151361149 NCBI chr 6:111,087,503...111,231,194
Ensembl chr 6:111,087,503...111,231,194 		JBrowse link
G SLC1A5 solute carrier family 1 member 5 disease_progression IEP protein:increased expression:esophagus RGD PMID:33609949 PMID:26936531 RGD:151361149, RGD:11532833 NCBI chr19:46,774,883...46,788,594
Ensembl chr19:46,774,883...46,788,594 		JBrowse link
G SLC39A6 solute carrier family 39 member 6 EXP CTD Direct Evidence: therapeutic CTD PMID:23644492 NCBI chr18:36,108,531...36,129,340
Ensembl chr18:36,108,531...36,129,385 		JBrowse link
G SLC52A3 solute carrier family 52 member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20729853 NCBI chr20:760,080...780,033
Ensembl chr20:760,080...776,015 		JBrowse link
G SLC7A5 solute carrier family 7 member 5 disease_progression IEP protein:increased expression:esophagus RGD PMID:31726270 PMID:26936531 PMID:33609949 RGD:151361144, RGD:11532833, RGD:151361149 NCBI chr16:87,830,023...87,869,507
Ensembl chr16:87,830,016...87,869,507 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 severity
treatment		 IEP
ISO		 mRNA:decreased expression:esophagus RGD PMID:21385099 PMID:31728180 PMID:28233302 RGD:150573691, RGD:150573815, RGD:150573812 NCBI chr16:11,254,417...11,256,204
Ensembl chr16:11,254,417...11,256,204 		JBrowse link
G SOD2 superoxide dismutase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18167182 PMID:21517111 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SOX2 SRY-box transcription factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19801978 NCBI chr 3:181,711,925...181,714,436
Ensembl chr 3:181,711,925...181,714,436 		JBrowse link
G SPEN spen family transcriptional repressor IAGP associated with Neoplasm Metastasis; DNA:mutations RGD PMID:33363385 RGD:151347445 NCBI chr 1:15,847,707...15,940,456
Ensembl chr 1:15,836,095...15,940,456 		JBrowse link
G STIM1 stromal interaction molecule 1 exacerbates HEP protein:increased expression:esophagus (human) RGD PMID:31843504 RGD:152995393 NCBI chr11:3,854,604...4,093,210
Ensembl chr11:3,854,527...4,093,210 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25129146 NCBI chr 5:139,475,533...139,482,758
Ensembl chr 5:139,475,533...139,482,935 		JBrowse link
G SULT1A1 sulfotransferase family 1A member 1 IAGP DNA:SNP:exon:p.R213H, 638G>A (human) RGD PMID:12455060 RGD:1581448 NCBI chr16:28,605,258...28,623,375
Ensembl chr16:28,605,196...28,610,044 		JBrowse link
G TAGLN transgelin EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr11:117,199,294...117,207,465
Ensembl chr11:117,199,370...117,207,464 		JBrowse link
G TAP1 transporter 1, ATP binding cassette subfamily B member IEP protein:decreased expression:esophagus RGD PMID:19492245 RGD:6482249 NCBI chr 6:32,845,209...32,853,704
Ensembl chr 6:32,845,209...32,853,816 		JBrowse link
G TAP2 transporter 2, ATP binding cassette subfamily B member IEP protein:decreased expression:esophagus RGD PMID:19492245 RGD:6482249 NCBI chr 6:32,821,831...32,838,739
Ensembl chr 6:32,821,833...32,838,739 		JBrowse link
G TCN2 transcobalamin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chr22:30,607,174...30,627,271
Ensembl chr22:30,607,003...30,627,271 		JBrowse link
G TERT telomerase reverse transcriptase susceptibility
no_association		 IAGP
IEP		 DNA:SNPs: : rs2853691,rs2736100(human)
mRNA:increased expression:esophagus squamous epithelium:
DNA:SNP: :rs2736098(human)		 RGD PMID:26716642 PMID:15112252 PMID:25007268 RGD:11572962, RGD:152977757, RGD:150530488 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068 		JBrowse link
G TET2 tet methylcytosine dioxygenase 2 severity IEP
IAGP		 mRNA:decreased expression:esophagus squamous epithelium (human)
associated with Lymphatic Metastasis;mRNA:decreased expression:esophagus squamous epithelium (human)
DNA:mutations		 RGD PMID:26093090 PMID:27050164 PMID:26873401 RGD:11528815, RGD:150429668, RGD:150429656 NCBI chr 4:105,145,875...105,279,803
Ensembl chr 4:105,145,875...105,279,816 		JBrowse link
G TET3 tet methylcytosine dioxygenase 3 IEP mRNA:decreased expression:esophagus squamous epithelium (human) RGD PMID:27050164 RGD:150429668 NCBI chr 2:73,983,631...74,135,498
Ensembl chr 2:73,984,910...74,108,177 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 IAGP OMIM NCBI chr 3:30,606,356...30,694,142
Ensembl chr 3:30,606,478...30,694,249 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 severity IEP mRNA,protein:increased expression:esophagus squamous epithelium (human) RGD PMID:28197630 RGD:151347617 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
G TNFAIP8 TNF alpha induced protein 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21969086 NCBI chr 5:119,268,759...119,399,688
Ensembl chr 5:119,268,692...119,399,688 		JBrowse link
G TNXB tenascin XB EXP CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chr 6:32,041,153...32,109,338
Ensembl chr 6:32,041,153...32,115,334 		JBrowse link
G TP53 tumor protein p53 IAGP
EXP
ISO		 DNA:misssense mutation: :p.R72P (rs1042522) (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16543248 PMID:25151357 PMID:28789369 RGD:14995932 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TPI1 triosephosphate isomerase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr12:6,867,420...6,870,948
Ensembl chr12:6,867,119...6,870,948 		JBrowse link
G TPM1 tropomyosin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr15:63,042,747...63,071,915
Ensembl chr15:63,042,620...63,071,915 		JBrowse link
G TPM2 tropomyosin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 9:35,681,993...35,690,056
Ensembl chr 9:35,681,992...35,690,056 		JBrowse link
G TXNDC17 thioredoxin domain containing 17 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr17:6,641,060...6,644,541
Ensembl chr17:6,640,985...6,644,541 		JBrowse link
G TYMP thymidine phosphorylase EXP CTD Direct Evidence: marker/mechanism CTD PMID:11641616 NCBI chr22:50,525,752...50,530,085
Ensembl chr22:50,525,752...50,530,032 		JBrowse link
G USP8 ubiquitin specific peptidase 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:35022897 NCBI chr15:50,424,405...50,514,421
Ensembl chr15:50,424,380...50,514,421 		JBrowse link
G VENTX VENT homeobox EXP CTD Direct Evidence: marker/mechanism CTD PMID:30431698 NCBI chr10:133,237,855...133,241,928
Ensembl chr10:133,237,855...133,241,928 		JBrowse link
G WRAP53 WD repeat containing antisense to TP53 disease_progression IEP RGD PMID:24626331 RGD:21081532 NCBI chr17:7,686,071...7,703,502
Ensembl chr17:7,686,071...7,703,502 		JBrowse link
G WWOX WW domain containing oxidoreductase IAGP
EXP		 esophageal squamous cell carcinoma, OMIM:133239
ClinVar Annotator: match by term: Esophageal squamous cell carcinoma
ClinVar Annotator: match by term: Esophageal squamous cell carcinoma, somatic
CTD Direct Evidence: marker/mechanism		 ClinVar
OMIM
CTD
RGD		 PMID:11956080 PMID:16199547 PMID:24456803 PMID:25411445 PMID:25526675 More... RGD:1599874 NCBI chr16:78,099,654...79,212,667
Ensembl chr16:78,099,400...79,212,667 		JBrowse link
G XPO1 exportin 1 exacerbates IEP mRNA, protein:increased expression:epithelium of esophagus (human)
protein:increased expression:esophagus (human)		 RGD PMID:24898882 PMID:25148895 RGD:151667431, RGD:151667436 NCBI chr 2:61,477,849...61,538,612
Ensembl chr 2:61,476,032...61,538,741 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 no_association
susceptibility
treatment		 EXP
IAGP		 CTD Direct Evidence: marker/mechanism
DNA:missense mutation:cds: p.R399Q (human)
DNA:SNPs,haplotypes:multiple (human)
DNA:SNPs:exon 6, exon 9, exon 10:multiple (human)		 CTD
RGD		 PMID:16639733 PMID:11400117 PMID:25710005 PMID:27123143 PMID:28356949 RGD:151347444, RGD:150530501, RGD:150530634, RGD:150530505 NCBI chr19:43,543,311...43,575,527
Ensembl chr19:43,543,311...43,580,473 		JBrowse link
G ZCCHC12 zinc finger CCHC-type containing 12 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30431698 NCBI chr  X:118,823,824...118,826,968
Ensembl chr  X:118,823,824...118,826,968 		JBrowse link
Ferguson-Smith tumor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC130002223 ATAC-STARR-seq lymphoblastoid silent region 20124 IAGP ClinVar Annotator: match by term: Ferguson-Smith type epithelioma ClinVar PMID:25741868 NCBI chr 9:99,104,641...99,105,240 JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 EXP
IAGP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Ferguson-Smith type epithelioma
ClinVar Annotator: match by term: Multiple self-healing squamous epithelioma
ClinVar Annotator: match by term: Ferguson-Smith type epithelioma | ClinVar Annotator: match by term: Multiple self-healing squamous epithelioma		 CTD
OMIM
ClinVar		 PMID:2511639 PMID:2647812 PMID:5173258 PMID:8499949 PMID:9536098 More... NCBI chr 9:99,103,647...99,154,192
Ensembl chr 9:99,104,038...99,154,192 		JBrowse link
focal nonepidermolytic palmoplantar keratoderma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KRT16 keratin 16 IAGP ClinVar Annotator: match by term: Palmoplantar keratoderma, nonepidermolytic, focal ClinVar PMID:8595410 PMID:16250206 PMID:22336941 PMID:24611874 PMID:25741868 More... NCBI chr17:41,609,778...41,612,767
Ensembl chr17:41,609,778...41,615,899 		JBrowse link
G KRT6C keratin 6C IAGP ClinVar Annotator: match by term: Focal palmoplantar keratoderma ClinVar PMID:19609311 NCBI chr12:52,468,516...52,473,805
Ensembl chr12:52,468,516...52,473,805 		JBrowse link
G SPATA22 spermatogenesis associated 22 IAGP ClinVar Annotator: match by term: Isolated focal non-epidermolytic palmoplantar keratoderma ClinVar PMID:25741868 NCBI chr17:3,440,019...3,513,858
Ensembl chr17:3,440,019...3,513,852 		JBrowse link
G TRPV3 transient receptor potential cation channel subfamily V member 3 IAGP ClinVar Annotator: match by term: Isolated focal non-epidermolytic palmoplantar keratoderma ClinVar PMID:9536098 PMID:17576681 PMID:21285946 PMID:24452206 PMID:25285920 More... NCBI chr17:3,510,502...3,557,812
Ensembl chr17:3,510,502...3,557,812 		JBrowse link
focal nonepidermolytic palmoplantar keratoderma 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KRT16 keratin 16 IAGP ClinVar Annotator: match by term: Palmoplantar keratoderma, nonepidermolytic, focal 1 OMIM
ClinVar		 PMID:8595410 PMID:16250206 PMID:22336941 PMID:22668561 PMID:24491404 More... NCBI chr17:41,609,778...41,612,767
Ensembl chr17:41,609,778...41,615,899 		JBrowse link
focal nonepidermolytic palmoplantar keratoderma 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TRPV3 transient receptor potential cation channel subfamily V member 3 IAGP ClinVar Annotator: match by term: Palmoplantar keratoderma, nonepidermolytic, focal 2 | ClinVar Annotator: match by term: TRPV3-related condition OMIM
ClinVar		 PMID:25741868 PMID:28492532 NCBI chr17:3,510,502...3,557,812
Ensembl chr17:3,510,502...3,557,812 		JBrowse link
glottis squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WRAP53 WD repeat containing antisense to TP53 disease_progression IEP RGD PMID:28849066 RGD:21081521 NCBI chr17:7,686,071...7,703,502
Ensembl chr17:7,686,071...7,703,502 		JBrowse link
head and neck squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25275603 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) EXP CTD Direct Evidence: marker/mechanism CTD PMID:25275603 NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25275603 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) EXP CTD Direct Evidence: marker/mechanism CTD PMID:25275603 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628 		JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase IAGP ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:31775759 NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,043...130,887,675 		JBrowse link
G ACOD1 aconitate decarboxylase 1 IEP mRNA:increased expression:cranioceervical (human) RGD PMID:37793345 RGD:596992333 NCBI chr13:76,948,511...76,958,638
Ensembl chr13:76,948,511...76,958,638 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23873848 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G ANKRD17 ankyrin repeat domain 17 IAGP ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:28580594 NCBI chr 4:73,073,376...73,258,798
Ensembl chr 4:73,073,376...73,258,798 		JBrowse link
G ATP7B ATPase copper transporting beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:12509969 NCBI chr13:51,932,669...52,012,132
Ensembl chr13:51,930,436...52,012,125 		JBrowse link
G B2M beta-2-microglobulin IAGP ClinVar Annotator: match by term: Head and neck squamous cell carcinoma | ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:26619011 NCBI chr15:44,711,517...44,718,145
Ensembl chr15:44,711,358...44,718,851 		JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 exacerbates HEP mRNA:increased expression:head or neck skin (human) RGD PMID:31964418 RGD:153344516 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 ameliorates HEP mRNA:increased expression:head or neck skin (human) RGD PMID:31964418 RGD:153344516 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase IAGP ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:31775759 NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929 		JBrowse link
G CASP8 caspase 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23358896 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CCDC3 coiled-coil domain containing 3 IAGP ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:26614431 NCBI chr10:12,896,625...13,099,989
Ensembl chr10:12,896,625...13,099,652 		JBrowse link
G CCNA1 cyclin A1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23358896 PMID:29464035 NCBI chr13:36,431,517...36,442,870
Ensembl chr13:36,431,520...36,442,870 		JBrowse link
G CCNA2 cyclin A2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883 		JBrowse link
G CCNB1 cyclin B1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245 		JBrowse link
G CCND1 cyclin D1 disease_progression IAGP
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:26909611 PMID:29464035 PMID:9796972 RGD:13434911 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CCNE1 cyclin E1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312 		JBrowse link
G CCNE2 cyclin E2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chr 8:94,880,224...94,896,693
Ensembl chr 8:94,879,770...94,896,678 		JBrowse link
G CDC73 cell division cycle 73 exacerbates IEP protein:increased expression:squamous epithelium (human) RGD PMID:26124004 RGD:11065919 NCBI chr 1:193,122,031...193,254,815
Ensembl chr 1:193,121,983...193,254,815 		JBrowse link
G CDK2 cyclin dependent kinase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789 		JBrowse link
G CDK4 cyclin dependent kinase 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013 		JBrowse link
G CDK6 cyclin dependent kinase 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chr 7:92,604,921...92,836,573
Ensembl chr 7:92,604,921...92,836,573 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A disease_progression IAGP
EXP		 DNA:SNPs: :rs3731217, rs3088440 (human)
ClinVar Annotator: match by term: Lip and oral cavity carcinoma
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
RGD		 PMID:7718873 PMID:8153634 PMID:8668202 PMID:9166859 PMID:11687599 More... RGD:8552291 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301 		JBrowse link
G CHD4 chromodomain helicase DNA binding protein 4 HEP mRNA:increased expression:head or neck skin (human) RGD PMID:28486105 RGD:153323299 NCBI chr12:6,570,082...6,607,379
Ensembl chr12:6,570,082...6,614,524 		JBrowse link
G CLDN1 claudin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:33665778 NCBI chr 3:190,305,707...190,322,446
Ensembl chr 3:190,305,707...190,322,446 		JBrowse link
G CNTN4 contactin 4 IAGP ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:28595731 NCBI chr 3:2,098,866...3,057,959
Ensembl chr 3:2,098,813...3,057,959 		JBrowse link
G CREBBP CREB binding protein IAGP ClinVar Annotator: match by term: Head and neck squamous cell carcinoma | ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:21390126 PMID:21680795 PMID:21796119 PMID:22832583 PMID:23334668 More... NCBI chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713 		JBrowse link
G CTNNB1 catenin beta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34019859 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096 		JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 treatment IAGP DNA:polymorphisms: :CYP2C19*2(human) RGD PMID:19954746 RGD:401901267 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547 		JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 treatment IAGP DNA:polymorphisms: :CYP2C9*2(human) RGD PMID:19954746 RGD:401901267 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091 		JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene) treatment IAGP DNA:polymorphisms: :CYP2D6*4,CYP2D6*10(human) RGD PMID:19954746 RGD:401901267 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865 		JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 severity IEP RGD PMID:24556606 RGD:150429746 NCBI chr 1:162,630,863...162,787,405
Ensembl chr 1:162,631,373...162,787,405 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta susceptibility IAGP DNA:SNP,haplotype:promoter:-149C>T,-579G>T(human) RGD PMID:18455294 RGD:9589078 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359 		JBrowse link
G EGFR epidermal growth factor receptor IAGP ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck
ClinVar Annotator: match by term: Head and neck squamous cell carcinoma
ClinVar Annotator: match by term: Lip and oral cavity carcinoma		 ClinVar PMID:15118073 PMID:15118125 PMID:15788655 PMID:17285735 PMID:19060236 More... NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EGFR-AS1 EGFR antisense RNA 1 IAGP ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:17285735 PMID:19060236 PMID:19096301 PMID:22980975 PMID:23242437 More... NCBI chr 7:55,179,750...55,188,949
Ensembl chr 7:55,179,750...55,212,969 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 disease_progression IEP RGD PMID:20604875 RGD:126790467 NCBI chr17:39,688,094...39,728,658
Ensembl chr17:39,687,914...39,730,426 		JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 severity IEP RGD PMID:20604875 RGD:126790467 NCBI chr 2:211,375,717...212,538,802
Ensembl chr 2:211,375,717...212,538,841 		JBrowse link
G FANCB FA complementation group B IDA DNA:hypermethylation:promoter RGD PMID:20332657 RGD:11344903 NCBI chr  X:14,689,524...14,873,069
Ensembl chr  X:14,690,388...14,873,255 		JBrowse link
G FANCD2 FA complementation group D2 ISO RGD PMID:20935219 RGD:11344907 NCBI chr 3:10,026,437...10,101,932
Ensembl chr 3:10,026,370...10,101,932 		JBrowse link
G FGFR4 fibroblast growth factor receptor 4 severity IAGP DNA:SNP:exon 9: p.G388R (human) RGD PMID:17084840 RGD:150520023 NCBI chr 5:177,086,915...177,098,144
Ensembl chr 5:177,086,905...177,098,144 		JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase IAGP ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:28580594 NCBI chr 3:59,747,277...61,251,452
Ensembl chr 3:59,747,277...61,251,459 		JBrowse link
G GRIK2 glutamate ionotropic receptor kainate type subunit 2 IAGP ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:26614431 NCBI chr 6:101,393,708...102,070,083
Ensembl chr 6:100,962,701...102,081,622 		JBrowse link
G HOXA5 homeobox A5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22227861 NCBI chr 7:27,141,052...27,143,681
Ensembl chr 7:27,141,052...27,143,681 		JBrowse link
G HOXD10 homeobox D10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22227861 NCBI chr 2:176,116,778...176,119,937
Ensembl chr 2:176,108,790...176,119,937 		JBrowse link
G HOXD11 homeobox D11 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22227861 NCBI chr 2:176,107,280...176,115,679
Ensembl chr 2:176,104,216...176,109,754 		JBrowse link
G HRAS HRas proto-oncogene, GTPase IAGP ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck
ClinVar Annotator: match by term: Lip and oral cavity carcinoma		 ClinVar PMID:2105486 PMID:11150980 PMID:12727991 PMID:12835555 PMID:16155195 More... NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321 		JBrowse link
G IFNL3 interferon lambda 3 EXP CTD Direct Evidence: therapeutic CTD PMID:21304406 NCBI chr19:39,243,455...39,245,250
Ensembl chr19:39,243,455...39,245,250 		JBrowse link
G IGF1 insulin like growth factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30594912 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
G IL1A interleukin 1 alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:27738319 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1RAP interleukin 1 receptor accessory protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:27738319 NCBI chr 3:190,514,085...190,659,750
Ensembl chr 3:190,514,051...190,659,750 		JBrowse link
G IL2 interleukin 2 IDA RGD PMID:3263896 PMID:2787951 RGD:8662923, RGD:8662971 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G ING1 inhibitor of growth family member 1 IAGP
EXP		 ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD		 PMID:10866301 NCBI chr13:110,712,623...110,723,339
Ensembl chr13:110,712,736...110,723,339 		JBrowse link
G IRS1 insulin receptor substrate 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30594912 NCBI chr 2:226,731,312...226,799,820
Ensembl chr 2:226,731,312...226,799,820 		JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit ameliorates IMP human cell line in a mouse model RGD PMID:26754630 RGD:11556098 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315 		JBrowse link
G KISS1 KiSS-1 metastasis suppressor EXP CTD Direct Evidence: therapeutic CTD PMID:21383688 NCBI chr 1:204,190,341...204,196,491
Ensembl chr 1:204,190,341...204,196,491 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase IAGP ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:22703879 PMID:24728327 PMID:25741868 PMID:28492532 PMID:31775759 NCBI chr 4:54,657,957...54,740,715
Ensembl chr 4:54,657,267...54,740,783 		JBrowse link
G LNX1 ligand of numb-protein X 1 IAGP ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:26614431 NCBI chr 4:53,459,301...53,652,477
Ensembl chr 4:53,459,301...53,701,405 		JBrowse link
G LOC126806658 BRD4-independent group 4 enhancer GRCh37_chr3:41265899-41267098 IAGP ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:25157968 PMID:26619011 NCBI chr 3:41,224,408...41,225,607 JBrowse link
G LOC126862483 BRD4-independent group 4 enhancer GRCh37_chr17:7589699-7590898 IAGP ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar NCBI chr17:7,686,360...7,687,580 JBrowse link
G LOC130062899 ATAC-STARR-seq lymphoblastoid active region 13597 IAGP ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:25741868 PMID:26467025 PMID:28492532 PMID:31775759 PMID:34326862 NCBI chr19:1,223,046...1,223,255 JBrowse link
G LRRC56 leucine rich repeat containing 56 IAGP ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:2105486 PMID:11150980 PMID:12727991 PMID:12835555 PMID:16155195 More... NCBI chr11:506,462...554,912
Ensembl chr11:537,527...554,912 		JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase EXP CTD Direct Evidence: marker/mechanism CTD PMID:24991542 NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983 		JBrowse link
G MIR155 microRNA 155 IEP RGD PMID:30617160 RGD:21081517 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044 		JBrowse link
G MIR222 microRNA 222 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19487542 NCBI chr  X:45,747,015...45,747,124
Ensembl chr  X:45,747,015...45,747,124 		JBrowse link
G MIR494 microRNA 494 exacerbates IMP RGD PMID:26090866 RGD:11529207 NCBI chr14:101,029,634...101,029,714
Ensembl chr14:101,029,634...101,029,714 		JBrowse link
G MMP2 matrix metallopeptidase 2 IAGP ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:28595731 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G NAIP NLR family apoptosis inhibitory protein ameliorates HEP mRNA:increased expression:head or neck skin (human) RGD PMID:31964418 RGD:153344516 NCBI chr 5:70,968,166...71,025,339
Ensembl chr 5:70,968,166...71,025,339 		JBrowse link
G NAMPT nicotinamide phosphoribosyltransferase EXP CTD Direct Evidence: marker/mechanism CTD PMID:28501332 NCBI chr 7:106,248,298...106,285,888
Ensembl chr 7:106,248,298...106,285,966 		JBrowse link
G NDRG1 N-myc downstream regulated 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22972152 NCBI chr 8:133,237,175...133,297,252
Ensembl chr 8:133,237,175...133,302,022 		JBrowse link
G NSDHL NAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL EXP CTD Direct Evidence: marker/mechanism CTD PMID:23125191 NCBI chr  X:152,831,063...152,869,729
Ensembl chr  X:152,830,967...152,869,729 		JBrowse link
G OGG1 8-oxoguanine DNA glycosylase susceptibility IEP
IAGP		 DNA:SNP: :rs1052133 (human) RGD PMID:22081374 PMID:21727658 RGD:8657144, RGD:8657147 NCBI chr 3:9,749,952...9,783,108
Ensembl chr 3:9,749,944...9,788,219 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha EXP
IAGP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Lip and oral cavity carcinoma
ClinVar Annotator: match by term: Head and neck squamous cell carcinoma		 CTD
ClinVar		 PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093 		JBrowse link
G PREX2 phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 IAGP ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:26614431 NCBI chr 8:67,952,046...68,237,032
Ensembl chr 8:67,952,046...68,237,032 		JBrowse link
G PTEN phosphatase and tensin homolog IAGP
EXP		 ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck
ClinVar Annotator: match by term: Head and neck squamous cell carcinoma
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD		 PMID:11801303 PMID:23873848 PMID:24033266 PMID:24055113 PMID:25741868 More... NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12969226 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTPN13 protein tyrosine phosphatase non-receptor type 13 susceptibility IAGP DNA:SNPs:cds:c.4566 A>G(I1522M)(rs2230600), c.6241 T>G (Y2081D)(rs989902)(human)
DNA:missense mutations:cds:p.I1522M, p.Y2081D (human)		 RGD PMID:19892796 PMID:19672627 RGD:152176661, RGD:152176665 NCBI chr 4:86,594,315...86,815,161
Ensembl chr 4:86,594,315...86,815,171 		JBrowse link
G RASGRP3 RAS guanyl releasing protein 3 IAGP ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:26614431 NCBI chr 2:33,436,348...33,564,731
Ensembl chr 2:33,436,324...33,586,669 		JBrowse link
G RB1 RB transcriptional corepressor 1 IAGP ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:31775759 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436 		JBrowse link
G SAMD4A sterile alpha motif domain containing 4A IAGP ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:28580594 NCBI chr14:54,565,316...54,793,315
Ensembl chr14:54,566,117...54,793,315 		JBrowse link
G SERPINE1 serpin family E member 1 severity IEP protein:increased expression:oral mucosa (human) RGD PMID:15878520 RGD:8547730 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SMAD4 SMAD family member 4 ISO RGD PMID:19841536 RGD:12880035 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,528...51,085,045 		JBrowse link
G SNTB1 syntrophin beta 1 IAGP ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:28595731 NCBI chr 8:120,535,756...120,812,046
Ensembl chr 8:120,535,745...120,813,273 		JBrowse link
G SOD2 superoxide dismutase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20618948 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 treatment IMP
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:27064016 PMID:24395569 RGD:8694302 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G STK11 serine/threonine kinase 11 IAGP ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:25741868 PMID:26467025 PMID:28492532 PMID:31775759 PMID:34326862 NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431 		JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a IAGP DNA:missense mutation:cds:p.E228A (c.683A>C) (human) RGD PMID:16217763 RGD:11038717 NCBI chr 8:23,190,452...23,225,102
Ensembl chr 8:23,190,452...23,225,102 		JBrowse link
G TNFRSF10B TNF receptor superfamily member 10b IAGP
EXP		 ClinVar Annotator: match by term: TNFRSF10B-related condition
ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD		 PMID:25741868 PMID:28492532 NCBI chr 8:23,020,133...23,069,031
Ensembl chr 8:23,020,133...23,069,031 		JBrowse link
G TP53 tumor protein p53 IAGP
EXP		 ClinVar Annotator: match by term: Head and neck squamous cell carcinoma
ClinVar Annotator: match by term: Lip and oral cavity carcinoma
ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck
ClinVar Annotator: match by term: Squamous cell carcinoma, head and neck, somatic
ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck | ClinVar Annotator: match by term: Squamous cell carcinoma, head and neck, somatic
ClinVar Annotator: match by term: Head and neck squamous cell carcinoma | ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD		 PMID:1349102 PMID:1349175 PMID:1565143 PMID:1565144 PMID:1581912 More... NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G VAMP7 vesicle associated membrane protein 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23358896 NCBI chr  X:155,881,345...155,943,769
NCBI chr  Y:57,067,865...57,130,289
Ensembl chr  Y:57,067,865...57,130,289
Ensembl chr  X:57,067,865...57,130,289 		JBrowse link
G WEE1 WEE1 G2 checkpoint kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:25125259 NCBI chr11:9,573,670...9,589,985
Ensembl chr11:9,573,670...9,593,457 		JBrowse link
G WRAP53 WD repeat containing antisense to TP53 treatment IEP
IAGP
IMP		 ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar
RGD		 PMID:25456005 PMID:25070141 RGD:21081529, RGD:21081533 NCBI chr17:7,686,071...7,703,502
Ensembl chr17:7,686,071...7,703,502 		JBrowse link
G YAP1 Yes1 associated transcriptional regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:20729916 NCBI chr11:102,110,447...102,233,424
Ensembl chr11:102,110,447...102,233,424 		JBrowse link
Ichthyosis Hystrix Gravior term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KRT10 keratin 10 IAGP ClinVar Annotator: match by term: Ichthyosis hystrix gravior OMIM
ClinVar		 PMID:17355236 PMID:27212473 NCBI chr17:40,818,117...40,822,614
Ensembl chr17:40,818,117...40,822,614 		JBrowse link
G KRT10-AS1 KRT10 antisense RNA 1 IAGP ClinVar Annotator: match by term: Ichthyosis hystrix gravior ClinVar PMID:17355236 PMID:27212473 NCBI chr17:40,819,145...40,836,274
Ensembl chr17:40,819,071...40,836,273 		JBrowse link
immunodeficiency 123 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD28 CD28 molecule IAGP ClinVar Annotator: match by term: Immunodeficiency 123 with HPV-related verrucosis OMIM
ClinVar		 NCBI chr 2:203,706,482...203,738,912
Ensembl chr 2:203,706,517...203,739,756 		JBrowse link
immunodeficiency 129 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RHOH ras homolog family member H IAGP ClinVar Annotator: match by term: Epidermodysplasia verruciformis, susceptibility to, 4
ClinVar Annotator: match by term: RHOH-related condition		 ClinVar
OMIM		 PMID:22850876 PMID:25741868 PMID:28492532 PMID:38775840 NCBI chr 4:40,191,080...40,246,967
Ensembl chr 4:40,191,011...40,246,967 		JBrowse link
immunodeficiency 130 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL7 interleukin 7 IAGP ClinVar Annotator: match by term: Epidermodysplasia verruciformis, susceptibility to, 5 | ClinVar Annotator: match by term: IL7-related condition OMIM
ClinVar		 PMID:25741868 PMID:25981006 PMID:28492532 PMID:31900472 PMID:39352394 NCBI chr 8:78,675,044...78,805,463
Ensembl chr 8:78,675,743...78,805,523 		JBrowse link
inverted papilloma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN1A cyclin dependent kinase inhibitor 1A IEP protein:increased expression:nucleus: RGD PMID:19863319 PMID:21608063 RGD:8662353, RGD:8662357 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G HGF hepatocyte growth factor IEP protein:increased expression:inferior nasal concha: RGD PMID:22730814 RGD:8548614 NCBI chr 7:81,699,010...81,770,047
Ensembl chr 7:81,699,010...81,770,438 		JBrowse link
G KDR kinase insert domain receptor IEP protein:increased expression:inferior nasal concha: RGD PMID:12541477 RGD:8551779 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595 		JBrowse link
G VEGFA vascular endothelial growth factor A IEP protein:increased expression:inferior nasal concha: RGD PMID:12541477 RGD:8551779 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
keratoacanthoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOTCH1 notch receptor 1 IAGP ClinVar Annotator: match by term: Keratoacanthoma ClinVar PMID:27283355 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048 		JBrowse link
G NOTCH2 notch receptor 2 IAGP ClinVar Annotator: match by term: Keratoacanthoma ClinVar PMID:27283355 NCBI chr 1:119,911,553...120,069,662
Ensembl chr 1:119,911,553...120,100,779 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha IAGP ClinVar Annotator: match by term: Keratoacanthoma ClinVar PMID:22949682 PMID:23246288 PMID:25741868 PMID:27283355 PMID:28151489 More... NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093 		JBrowse link
Laryngeal Papillomatosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTGS2 prostaglandin-endoperoxide synthase 2 IMP RGD PMID:19736197 RGD:5135499 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G SERPINA3 serpin family A member 3 IEP protein:decreased expression:serum RGD PMID:16273852 RGD:5147435 NCBI chr14:94,612,391...94,624,053
Ensembl chr14:94,612,384...94,624,055 		JBrowse link
G TAP1 transporter 1, ATP binding cassette subfamily B member IDA RGD PMID:10618282 RGD:5147846 NCBI chr 6:32,845,209...32,853,704
Ensembl chr 6:32,845,209...32,853,816 		JBrowse link
laryngeal squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase IEP protein:decreased activity:larynx RGD PMID:8138195 RGD:152995273 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252 		JBrowse link
G CAT catalase IEP protein:increased activity:larynx RGD PMID:8138195 RGD:152995273 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CDC73 cell division cycle 73 disease_progression IEP protein:decreased expression:larynx (human) RGD PMID:27334641 RGD:150539447 NCBI chr 1:193,122,031...193,254,815
Ensembl chr 1:193,121,983...193,254,815 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A IEP RGD PMID:15646812 RGD:8662837 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G CHD4 chromodomain helicase DNA binding protein 4 exacerbates HEP mRNA:increased expression:larynx (human) RGD PMID:33315534 RGD:153323310 NCBI chr12:6,570,082...6,607,379
Ensembl chr12:6,570,082...6,614,524 		JBrowse link
G EGFR epidermal growth factor receptor disease_progression IEP RGD PMID:22549618 RGD:126790474 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 disease_progression IEP RGD PMID:22549618 RGD:126790474 NCBI chr17:39,688,094...39,728,658
Ensembl chr17:39,687,914...39,730,426 		JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 disease_progression IEP RGD PMID:22549618 RGD:126790474 NCBI chr12:56,080,108...56,103,505
Ensembl chr12:56,076,799...56,103,505 		JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 disease_progression IEP RGD PMID:22549618 RGD:126790474 NCBI chr 2:211,375,717...212,538,802
Ensembl chr 2:211,375,717...212,538,841 		JBrowse link
G FOXL2 forkhead box L2 exacerbates IEP mRNA:increased expression:larynx (human) RGD PMID:32517588 RGD:151667913 NCBI chr 3:138,944,224...138,947,137
Ensembl chr 3:138,944,224...138,947,137 		JBrowse link
G GPX1 glutathione peroxidase 1 disease_progression
no_association		 IEP
IAGP		 protein:increased expression:larynx (human)
DNA:missense mutation:CDS:p.P198L (human)
DNA:missense mutation:CDS:p.P198L (rs1050450) (human)		 RGD PMID:28641905 PMID:24074040 PMID:27188866 RGD:152995454, RGD:152995493, RGD:152995455 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 severity IEP associated with Neoplasm Metastasis; protein:mRNA,increased expression:larynx epithelium (human) RGD PMID:19513509 RGD:150429781 NCBI chr17:12,020,877...12,143,828
Ensembl chr17:12,020,829...12,143,830 		JBrowse link
G MIR10A microRNA 10a severity HEP miRNA:decreased expression:blood serum (human) RGD PMID:35117730 RGD:153344530 NCBI chr17:48,579,838...48,579,947
Ensembl chr17:48,579,838...48,579,947 		JBrowse link
G MIR136 microRNA 136 IEP RNA:decreased expression:larynx (human) RGD PMID:32014687 RGD:153344610 NCBI chr14:100,884,702...100,884,783
Ensembl chr14:100,884,702...100,884,783 		JBrowse link
G MIR21 microRNA 21 exacerbates HEP miRNA:increased expression:blood serum (human) RGD PMID:35117730 RGD:153344530 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G MIR31 microRNA 31 disease_progression IEP RNA:decreased expression:mucosa of larynx (human) RGD PMID:29737563 RGD:152998933 NCBI chr 9:21,512,115...21,512,185
Ensembl chr 9:21,512,115...21,512,185 		JBrowse link
G MLH1 mutL homolog 1 disease_progression IEP mRNA:decreased expression:larynx RGD PMID:23787767 RGD:126848783 NCBI chr 3:36,993,466...37,050,846
Ensembl chr 3:36,993,226...37,050,896 		JBrowse link
G MMP2 matrix metallopeptidase 2 IEP RGD PMID:17786346 RGD:5130203 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MSH2 mutS homolog 2 disease_progression IEP mRNA:decreased expression:larynx RGD PMID:23787767 RGD:126848783 NCBI chr 2:47,403,067...47,709,830
Ensembl chr 2:47,403,067...47,663,146 		JBrowse link
G NAT2 N-acetyltransferase 2 susceptibility IAGP DNA:polymorphisms: : RGD PMID:19922706 PMID:16155914 RGD:5131602, RGD:5131856 NCBI chr 8:18,386,301...18,401,218
Ensembl chr 8:18,391,282...18,401,218 		JBrowse link
G PLCG1 phospholipase C gamma 1 ameliorates IEP mRNA:increased expression:larynx (human) RGD PMID:33466212 RGD:151665160 NCBI chr20:41,137,543...41,177,626
Ensembl chr20:41,136,960...41,196,801 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit severity IEP associated with Neoplasm Metastasis; protein:mRNA,increased expression:larynx epithelium (human) RGD PMID:19513509 RGD:150429781 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G XDH xanthine dehydrogenase IEP protein:increased activity:larynx RGD PMID:8138195 RGD:152995273 NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 IAGP ClinVar Annotator: match by term: Laryngeal squamous cell carcinoma ClinVar NCBI chr19:43,543,311...43,575,527
Ensembl chr19:43,543,311...43,580,473 		JBrowse link
lung squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALK ALK receptor tyrosine kinase IAGP ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:24033266 PMID:24728327 PMID:25741868 PMID:28492532 NCBI chr 2:29,192,774...29,921,586
Ensembl chr 2:29,192,774...29,921,586 		JBrowse link
G ARHGAP44 Rho GTPase activating protein 44 HEP mRNA:decreased expression:lung (human) RGD PMID:28527113 RGD:401901290 NCBI chr17:12,789,498...12,991,643
Ensembl chr17:12,789,498...12,991,643 		JBrowse link
G ARID1A AT-rich interaction domain 1A exacerbates HEP protein:decreased expression:lung (human) RGD PMID:32823232 RGD:126848760 NCBI chr 1:26,696,015...26,782,104
Ensembl chr 1:26,693,236...26,782,104 		JBrowse link
G ARPC5 actin related protein 2/3 complex subunit 5 IEP mRNA:increased expression:lung (human) RGD PMID:22089643 RGD:11049488 NCBI chr 1:183,620,846...183,635,783
Ensembl chr 1:183,620,846...183,635,783 		JBrowse link
G ATM ATM serine/threonine kinase susceptibility IAGP DNA:SNP:intron:(rs228589) (human) RGD PMID:28642860 RGD:150383339 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102 		JBrowse link
G ATRX ATRX chromatin remodeler severity IEP RGD PMID:31374064 RGD:127285382 NCBI chr  X:77,504,880...77,786,216
Ensembl chr  X:77,504,880...77,786,233 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 disease_progression HEP mRNA:increased expression:lung (human) RGD PMID:31964418 RGD:153344516 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636 		JBrowse link
G BIRC6 baculoviral IAP repeat containing 6 disease_progression HEP mRNA:increased expression:lung (human) RGD PMID:31964418 RGD:153344516 NCBI chr 2:32,357,023...32,618,878
Ensembl chr 2:32,357,023...32,619,571 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase IAGP ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:12068308 PMID:18186519 PMID:19537845 PMID:20350999 PMID:21129611 More... NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929 		JBrowse link
G BSG basigin (Ok blood group) IEP mRNA:increased expression:lung RGD PMID:9154157 RGD:2289059 NCBI chr19:571,283...583,493
Ensembl chr19:571,277...583,494 		JBrowse link
G CBLB Cbl proto-oncogene B disease_progression IEP RGD PMID:29384143 RGD:150540336 NCBI chr 3:105,655,461...105,869,449
Ensembl chr 3:105,655,461...105,869,552 		JBrowse link
G CCND1 cyclin D1 disease_progression IEP protein:increased expression:lung RGD PMID:27498289 RGD:13434929 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CCND2 cyclin D2 IDA DNA:hypermethylation:promoter RGD PMID:30308939 RGD:151665105 NCBI chr12:4,273,762...4,305,353
Ensembl chr12:4,269,771...4,305,353 		JBrowse link
G CDK4 cyclin dependent kinase 4 IEP protein:increased expression:lung RGD PMID:9751261 RGD:13464277 NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A IAGP ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:8552400 PMID:8573142 PMID:9053859 PMID:9660926 PMID:10498896 More... NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301 		JBrowse link
G CHD4 chromodomain helicase DNA binding protein 4 HEP mRNA:increased expression:lung (human) RGD PMID:28486105 RGD:153323299 NCBI chr12:6,570,082...6,607,379
Ensembl chr12:6,570,082...6,614,524 		JBrowse link
G CHRNA5 cholinergic receptor nicotinic alpha 5 subunit susceptibility IAGP
IEP		 DNA:SNP: :rs503464(human)
mRNA:increased expression:lung		 RGD PMID:23314339 PMID:20124469 RGD:150527849, RGD:150527851 NCBI chr15:78,565,520...78,595,269
Ensembl chr15:78,565,520...78,595,269 		JBrowse link
G CHRNB4 cholinergic receptor nicotinic beta 4 subunit susceptibility IEP
IDA
IAGP		 mRNA:increased expression:lung
DNA:hypomethylation:promoter:
DNA:SNP:: (rs7178270) (human)		 RGD PMID:20124469 PMID:22945651 PMID:23397474 RGD:150527851, RGD:151361154, RGD:151361148 NCBI chr15:78,624,111...78,661,641
Ensembl chr15:78,624,111...78,727,754 		JBrowse link
G CLPTM1L CLPTM1 like susceptibility
no_association		 IEP
IAGP		 mRNA:increased expression:lung
DNA:SNP: :rs401681(human)
DNA:SNP::rs401681(human)
DNA:SNP:: rs31490(human)		 RGD PMID:24366883 PMID:24386361 PMID:24861918 PMID:23908149 RGD:150530483, RGD:150537098, RGD:150530499, RGD:150530498 NCBI chr 5:1,317,752...1,345,099
Ensembl chr 5:1,317,752...1,345,099 		JBrowse link
G CREBBP CREB binding protein IAGP ClinVar Annotator: match by term: Squamous cell carcinoma of lung ClinVar PMID:21390126 PMID:21680795 PMID:21796119 PMID:22832583 PMID:23334668 More... NCBI chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713 		JBrowse link
G CSF1R colony stimulating factor 1 receptor IEP protein:increased expression:lung (human) RGD PMID:23702648 RGD:150524280 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372 		JBrowse link
G CTNNB1 catenin beta 1 disease_progression IEP protein:increased expression:lung RGD PMID:27498289 RGD:13434929 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096 		JBrowse link
G CYCS cytochrome c, somatic treatment IEP RGD PMID:25578497 RGD:13792769 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 susceptibility IAGP Carcinoma, Squamous Cell;DNA:snp:cds:p.A119S (human) RGD PMID:10739169 RGD:7829734 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 severity IAGP
IEP		 ClinVar Annotator: match by term: Squamous cell lung carcinoma
mRNA:increased expression:lung		 ClinVar
RGD		 PMID:22328973 PMID:25741868 PMID:28492532 PMID:22807955 PMID:24885564 RGD:150429703, RGD:150429702 NCBI chr 1:162,630,863...162,787,405
Ensembl chr 1:162,631,373...162,787,405 		JBrowse link
G E2F1 E2F transcription factor 1 treatment IDA RGD PMID:28927142 RGD:13464332 NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385 		JBrowse link
G E2F3 E2F transcription factor 3 IEP RGD PMID:16938365 RGD:13464341 NCBI chr 6:20,401,879...20,493,714
Ensembl chr 6:20,401,879...20,493,714 		JBrowse link
G EEF2 eukaryotic translation elongation factor 2 disease_progression HEP protein:increased expression:lung (human) RGD PMID:27542262 RGD:153298910 NCBI chr19:3,976,056...3,985,463
Ensembl chr19:3,976,056...3,985,463 		JBrowse link
G EGFR epidermal growth factor receptor IAGP ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:20942962 PMID:24033266 PMID:25382819 PMID:25741868 PMID:27294619 More... NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EGFR-AS1 EGFR antisense RNA 1 IAGP ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr 7:55,179,750...55,188,949
Ensembl chr 7:55,179,750...55,212,969 		JBrowse link
G EMX2 empty spiracles homeobox 2 exacerbates IEP protein:decreased expression:lung (human) RGD PMID:26132438 RGD:11079903 NCBI chr10:117,542,746...117,549,546
Ensembl chr10:117,542,445...117,549,546 		JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor IEP mRNA, protein:increased expression:lung (human) RGD PMID:31615563 RGD:155260344 NCBI chr10:49,434,881...49,539,538
Ensembl chr10:49,454,168...49,539,538 		JBrowse link
G ERCC6L ERCC excision repair 6 like, spindle assembly checkpoint helicase HEP mRNA:increased expression:lung (human) RGD PMID:35150321 RGD:155260359 NCBI chr  X:72,204,665...72,239,027
Ensembl chr  X:72,204,657...72,239,027 		JBrowse link
G FAP fibroblast activation protein alpha disease_progression IEP RGD PMID:26252379 RGD:152600901 NCBI chr 2:162,170,684...162,243,445
Ensembl chr 2:162,170,684...162,245,151 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 IAGP ClinVar Annotator: match by term: Squamous cell carcinoma of lung | ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:26619011 NCBI chr 4:152,320,544...152,536,092
Ensembl chr 4:152,320,544...152,536,092 		JBrowse link
G FGF9 fibroblast growth factor 9 IEP mRNA:decreased expression:lung (human) RGD PMID:28440022 RGD:152180844 NCBI chr13:21,671,073...21,704,498
Ensembl chr13:21,671,073...21,704,498 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 IAGP ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar NCBI chr10:121,478,330...121,598,458
Ensembl chr10:121,478,332...121,598,458 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 IAGP ClinVar Annotator: match by term: Squamous cell lung carcinoma
ClinVar Annotator: match by term: Squamous cell carcinoma of lung		 ClinVar PMID:8589699 PMID:10471491 PMID:11038465 PMID:11879084 PMID:15772091 More... NCBI chr 4:1,793,293...1,808,867
Ensembl chr 4:1,793,293...1,808,872 		JBrowse link
G FGFR4 fibroblast growth factor receptor 4 disease_progression IMP human cells in mouse model RGD PMID:29402970 RGD:150429984 NCBI chr 5:177,086,915...177,098,144
Ensembl chr 5:177,086,905...177,098,144 		JBrowse link
G FRZB frizzled related protein IEP protein:decreased expression:lung (human) RGD PMID:27623992 RGD:32716395 NCBI chr 2:182,833,275...182,866,637
Ensembl chr 2:182,833,275...182,866,637 		JBrowse link
G FUBP1 far upstream element binding protein 1 IEP mRNA:decreased expression:lung (human) RGD PMID:32481602 RGD:151361197 NCBI chr 1:77,944,055...77,979,501
Ensembl chr 1:77,944,055...77,979,110 		JBrowse link
G GPX1 glutathione peroxidase 1 susceptibility IAGP DNA:missense mutation:CDS:p.P198L (rs1050450) (human)
DNA:missense mutation:CDS:p.P200L (rs1050450) (human)		 RGD PMID:16797832 PMID:18298806 RGD:152995481, RGD:152995507 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G H3C2 H3 clustered histone 2 IAGP ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar NCBI chr 6:26,031,589...26,032,099
Ensembl chr 6:26,031,589...26,032,099 		JBrowse link
G HRAS HRas proto-oncogene, GTPase IAGP ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:16329078 PMID:16372351 PMID:16835863 PMID:17211612 PMID:17384584 More... NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321 		JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 IEP protein:increased expression:blood plasma (human) RGD PMID:24046070 RGD:149735540 NCBI chr 2:208,236,227...208,255,071
Ensembl chr 2:208,236,229...208,266,074 		JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 severity
susceptibility		 IEP
IAGP		 protein:increased expression:lung (human)
protein:increased expression:blood serum (human)
DNA:SNP:CD: (rs11540478) C>T (human)		 RGD PMID:30128035 PMID:29465809 PMID:27649069 RGD:149735564, RGD:149735567, RGD:149735566 NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,477 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase IAGP ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:25741868 NCBI chr 4:54,657,957...54,740,715
Ensembl chr 4:54,657,267...54,740,783 		JBrowse link
G KMT2D lysine methyltransferase 2D disease_progression IAGP RGD PMID:24323028 PMID:30885352 PMID:28177435 RGD:150523770, RGD:150523777, RGD:150523776 NCBI chr12:49,018,978...49,060,794
Ensembl chr12:49,018,975...49,060,794 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase IAGP ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:6695174 PMID:15696205 PMID:17704260 PMID:26242988 PMID:28492532 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936 		JBrowse link
G LAMC2 laminin subunit gamma 2 disease_progression IEP RGD PMID:23124251 RGD:13793371 NCBI chr 1:183,186,264...183,258,968
Ensembl chr 1:183,186,238...183,245,127 		JBrowse link
G LOC129996007 ATAC-STARR-seq lymphoblastoid active region 24180 IAGP ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar NCBI chr 6:26,032,006...26,032,125 JBrowse link
G LRRC56 leucine rich repeat containing 56 IAGP ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:16372351 PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr11:506,462...554,912
Ensembl chr11:537,527...554,912 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 IAGP ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:25741868 NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656 		JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 ISO mRNA:decreased expression:lung (human) RGD PMID:31089135 RGD:155253742 NCBI chr19:7,903,877...7,914,478
Ensembl chr19:7,903,843...7,914,478 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase IAGP ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar NCBI chr 7:116,672,196...116,798,377
Ensembl chr 7:116,672,196...116,798,377 		JBrowse link
G MIR154 microRNA 154 IEP associated with nicotine dependence; RNA:decreased expression:blood serum (human) RGD PMID:25386559 RGD:152995475 NCBI chr14:101,059,755...101,059,838
Ensembl chr14:101,059,755...101,059,838 		JBrowse link
G MIR193A microRNA 193a exacerbates IDA DNA:Hypermethylation RGD PMID:22282464 RGD:153344598 NCBI chr17:31,559,996...31,560,083
Ensembl chr17:31,559,996...31,560,083 		JBrowse link
G MIR20A microRNA 20a IEP RGD PMID:26560875 RGD:11572141 NCBI chr13:91,351,065...91,351,135
Ensembl chr13:91,351,065...91,351,135 		JBrowse link
G MIR210 microRNA 210 IEP miRNA:increased expression:sputum (human) RGD PMID:27777637 RGD:152998954 NCBI chr11:568,089...568,198
Ensembl chr11:568,089...568,198 		JBrowse link
G MIR31 microRNA 31 severity IEP RNA:increased expression:blood serum (human)
RNA:increased expression:lung (human)		 RGD PMID:21658006 PMID:21890451 RGD:152998938, RGD:152998950 NCBI chr 9:21,512,115...21,512,185
Ensembl chr 9:21,512,115...21,512,185 		JBrowse link
G MIR3662 microRNA 3662 disease_progression IEP RNA:increased expression:blood plasma (human) RGD PMID:28964576 RGD:153344625 NCBI chr 6:134,979,338...134,979,432
Ensembl chr 6:134,979,338...134,979,432 		JBrowse link
G MIR497 microRNA 497 IMP RGD PMID:31115562 RGD:126925181 NCBI chr17:7,017,911...7,018,022
Ensembl chr17:7,017,911...7,018,022 		JBrowse link
G MIR9-3 microRNA 9-3 exacerbates IDA DNA:Hypermethylation RGD PMID:22282464 RGD:153344598 NCBI chr15:89,368,017...89,368,106
Ensembl chr15:89,368,017...89,368,106 		JBrowse link
G MIR944 microRNA 944 disease_progression IEP RNA:increased expression:blood plasma (human) RGD PMID:28964576 RGD:153344625 NCBI chr 3:189,829,922...189,830,009
Ensembl chr 3:189,829,922...189,830,009 		JBrowse link
G PDGFRA platelet derived growth factor receptor alpha IAGP ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr 4:54,229,293...54,298,245
Ensembl chr 4:54,229,280...54,298,245 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha IAGP ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:25741868 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093 		JBrowse link
G POLE DNA polymerase epsilon, catalytic subunit ameliorates IAGP DNA:mutations:multiple (human) RGD PMID:29650000 RGD:151347653 NCBI chr12:132,623,762...132,687,342
Ensembl chr12:132,623,753...132,687,376 		JBrowse link
G PREX2 phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 IEP mRNA:increased expression:lung (human) RGD PMID:32537022 RGD:151665184 NCBI chr 8:67,952,046...68,237,032
Ensembl chr 8:67,952,046...68,237,032 		JBrowse link
G PTCH1 patched 1 disease_progression IAGP DNA:CNVs RGD PMID:21889114 RGD:150524337 NCBI chr 9:95,442,980...95,516,971
Ensembl chr 9:95,442,980...95,517,057 		JBrowse link
G PTEN phosphatase and tensin homolog IAGP ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G PTK2 protein tyrosine kinase 2 severity IEP RGD PMID:23906871 RGD:152176664 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 IAGP ClinVar Annotator: match by term: Squamous cell carcinoma of lung ClinVar PMID:11704759 PMID:12634870 PMID:12717436 PMID:14644997 PMID:14974085 More... NCBI chr12:112,418,947...112,509,918
Ensembl chr12:112,418,351...112,509,918 		JBrowse link
G PTPN13 protein tyrosine phosphatase non-receptor type 13 susceptibility
severity		 IEP
IAGP		 mRNA,protein:decreased expression:lung
DNA:missense mutations:cds:p.I1522M, p.Y2081D (human)		 RGD PMID:22245727 PMID:19672627 PMID:23906871 RGD:152176663, RGD:152176665, RGD:152176664 NCBI chr 4:86,594,315...86,815,161
Ensembl chr 4:86,594,315...86,815,171 		JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J susceptibility IAGP DNA:missense mutations:cds:p.R326Q, p.Q276P (human) RGD PMID:19672627 RGD:152176665 NCBI chr11:47,980,559...48,170,839
Ensembl chr11:47,980,425...48,170,839 		JBrowse link
G RAD52 RAD52 homolog, DNA repair protein ameliorates
susceptibility		 ISO
IAGP		 DNA:SNP: (rs6489769) (human) RGD PMID:28415565 PMID:22585858 RGD:151660334, RGD:151660345 NCBI chr12:911,736...991,122
Ensembl chr12:911,736...990,053 		JBrowse link
G SFTPB surfactant protein B susceptibility IAGP DNA:polymorphism:intron (human)
DNA:variants:intron:		 RGD PMID:16570259 PMID:12107845 RGD:4143389, RGD:151667424 NCBI chr 2:85,657,307...85,668,741
Ensembl chr 2:85,657,314...85,668,741 		JBrowse link
G SLC7A5 solute carrier family 7 member 5 IGI RGD PMID:19068093 RGD:151361158 NCBI chr16:87,830,023...87,869,507
Ensembl chr16:87,830,016...87,869,507 		JBrowse link
G SOX30 SRY-box transcription factor 30 disease_progression IEP RGD PMID:26330328 RGD:11535423 NCBI chr 5:157,625,679...157,671,480
Ensembl chr 5:157,625,679...157,671,480 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase severity IEP RGD PMID:12826049 RGD:150521546 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050 		JBrowse link
G SRSF1 serine and arginine rich splicing factor 1 IEP protein:increased expression:lung epithelium RGD PMID:23071587 RGD:150429662 NCBI chr17:57,989,038...58,007,246
Ensembl chr17:58,000,919...58,007,346 		JBrowse link
G SRSF2 serine and arginine rich splicing factor 2 IEP protein:increased expression:lung epithelium,nucleus RGD PMID:23071587 RGD:150429662 NCBI chr17:76,734,115...76,737,411
Ensembl chr17:76,734,115...76,737,333 		JBrowse link
G STK11 serine/threonine kinase 11 IAGP ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:25741868 PMID:28492532 NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431 		JBrowse link
G SULT1A1 sulfotransferase family 1A member 1 IAGP DNA:SNP:exon:p.R213H, 638G>A (human) RGD PMID:14688021 RGD:1581441 NCBI chr16:28,605,258...28,623,375
Ensembl chr16:28,605,196...28,610,044 		JBrowse link
G TERT telomerase reverse transcriptase susceptibility IAGP DNA:SNP:: rs2853669(human)
DNA:SNP::rs33963617(human)		 RGD PMID:23908149 PMID:31935503 RGD:150530498, RGD:150530635 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068 		JBrowse link
G TP53 tumor protein p53 IAGP ClinVar Annotator: match by term: Squamous cell carcinoma of lung
ClinVar Annotator: match by term: Squamous cell lung carcinoma		 ClinVar PMID:1565143 PMID:1565144 PMID:11370630 PMID:11793474 PMID:12726864 More... NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TP73 tumor protein p73 treatment HEP
IAGP		 mRNA:increased expression:lung (human)
DNA:SNP:: rs2273953(human)		 RGD PMID:30420492 PMID:27246533 RGD:151347580, RGD:151347584 NCBI chr 1:3,652,516...3,736,201
Ensembl chr 1:3,652,516...3,736,201 		JBrowse link
malignant mesothelioma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1B activin A receptor type 1B ameliorates IMP RGD PMID:30061637 RGD:151665492 NCBI chr12:51,951,699...51,997,078
Ensembl chr12:51,951,699...51,997,078 		JBrowse link
G ADA adenosine deaminase treatment IEP RGD PMID:17952507 RGD:152995277 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252 		JBrowse link
G ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26139392 NCBI chr 5:179,110,853...179,345,461
Ensembl chr 5:179,110,853...179,345,461 		JBrowse link
G AGO1 argonaute RISC component 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 1:35,869,761...35,930,532
Ensembl chr 1:35,869,808...35,930,532 		JBrowse link
G AGO2 argonaute RISC catalytic component 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 8:140,520,156...140,642,313
Ensembl chr 8:140,520,156...140,635,633 		JBrowse link
G ANXA2 annexin A2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20682992 NCBI chr15:60,347,151...60,397,986
Ensembl chr15:60,347,134...60,402,883 		JBrowse link
G APOA1 apolipoprotein A1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr11:116,835,751...116,837,622
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G BAP1 BRCA1 associated deubiquitinase 1 ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:24928783 PMID:25231345 PMID:26463840 PMID:26928227 PMID:29112861 More... RGD:9586039 NCBI chr 3:52,401,008...52,410,008
Ensembl chr 3:52,401,008...52,410,008 		JBrowse link
G BCL10 BCL10 immune signaling adaptor IAGP
EXP		 ClinVar Annotator: match by term: Mesothelioma, somatic
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Mesothelioma, malignant		 ClinVar
CTD
OMIM		 PMID:9989495 PMID:10380920 PMID:10408400 PMID:25741868 PMID:28492532 NCBI chr 1:85,265,776...85,276,632
Ensembl chr 1:85,265,776...85,276,632 		JBrowse link
G BCL2 BCL2 apoptosis regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:16850164 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G C9 complement C9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr 5:39,284,140...39,364,495
Ensembl chr 5:39,284,140...39,371,324 		JBrowse link
G CALB2 calbindin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr16:71,358,723...71,390,433
Ensembl chr16:71,358,713...71,390,436 		JBrowse link
G CCL23 C-C motif chemokine ligand 23 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr17:36,013,058...36,017,972
Ensembl chr17:36,013,056...36,017,972 		JBrowse link
G CCL27 C-C motif chemokine ligand 27 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 9:34,661,890...34,662,657
Ensembl chr 9:34,661,880...34,664,048 		JBrowse link
G CCL3 C-C motif chemokine ligand 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCL7 C-C motif chemokine ligand 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242 		JBrowse link
G CCNE2 cyclin E2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 8:94,880,224...94,896,693
Ensembl chr 8:94,879,770...94,896,678 		JBrowse link
G CD40 CD40 molecule treatment ISO RGD PMID:22002241 RGD:11522742 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CDH5 cadherin 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28377727 NCBI chr16:66,366,691...66,404,784
Ensembl chr16:66,366,690...66,404,784 		JBrowse link
G CDK6 cyclin dependent kinase 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 7:92,604,921...92,836,573
Ensembl chr 7:92,604,921...92,836,573 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A EXP CTD Direct Evidence: marker/mechanism CTD PMID:11453316 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A EXP CTD Direct Evidence: marker/mechanism CTD PMID:19223589 PMID:21526190 PMID:29112861 PMID:37441092 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301 		JBrowse link
G CFAP45 cilia and flagella associated protein 45 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26928227 NCBI chr 1:159,872,364...159,900,165
Ensembl chr 1:159,872,364...159,900,165 		JBrowse link
G CLDN10 claudin 10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28377727 NCBI chr13:95,433,755...95,579,759
Ensembl chr13:95,433,604...95,579,759 		JBrowse link
G CLDN15 claudin 15 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28377727 NCBI chr 7:101,232,094...101,238,820
Ensembl chr 7:101,232,092...101,238,820 		JBrowse link
G CLDN4 claudin 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28377727 NCBI chr 7:73,830,996...73,832,690
Ensembl chr 7:73,799,542...73,832,690 		JBrowse link
G CLDN5 claudin 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28377727 NCBI chr22:19,523,024...19,525,337
Ensembl chr22:19,523,024...19,527,545 		JBrowse link
G CLDN8 claudin 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28377727 NCBI chr21:30,214,006...30,216,097
Ensembl chr21:30,214,006...30,216,097 		JBrowse link
G CLEC11A C-type lectin domain containing 11A EXP CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr19:50,723,364...50,725,708
Ensembl chr19:50,723,364...50,725,708 		JBrowse link
G COL12A1 collagen type XII alpha 1 chain EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 6:75,084,326...75,206,053
Ensembl chr 6:75,084,326...75,206,267 		JBrowse link
G COPG1 COPI coat complex subunit gamma 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26463840 NCBI chr 3:129,249,606...129,277,773
Ensembl chr 3:129,249,606...129,277,773 		JBrowse link
G CSF1 colony stimulating factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 1:109,910,506...109,930,992
Ensembl chr 1:109,910,242...109,930,992 		JBrowse link
G CTNNB1 catenin beta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493 		JBrowse link
G CXCL13 C-X-C motif chemokine ligand 13 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr 4:77,511,753...77,611,834
Ensembl chr 4:77,511,753...77,611,834 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25162674 PMID:28377727 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509 		JBrowse link
G DDX3X DEAD-box helicase 3 X-linked EXP CTD Direct Evidence: marker/mechanism CTD PMID:26928227 NCBI chr  X:41,333,308...41,364,472
Ensembl chr  X:41,333,348...41,364,472 		JBrowse link
G DDX51 DEAD-box helicase 51 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26928227 NCBI chr12:132,136,594...132,144,319
Ensembl chr12:132,136,594...132,144,319 		JBrowse link
G EFEMP1 EGF containing fibulin extracellular matrix protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27032653 NCBI chr 2:55,865,967...55,923,782
Ensembl chr 2:55,865,967...55,924,139 		JBrowse link
G EGFR epidermal growth factor receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:27032653 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G ENOX2 ecto-NOX disulfide-thiol exchanger 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26807072 NCBI chr  X:130,622,325...130,903,209
Ensembl chr  X:130,622,325...130,903,234 		JBrowse link
G EPHX1 epoxide hydrolase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16697254 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563 		JBrowse link
G F9 coagulation factor IX EXP CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr  X:139,530,739...139,563,459
Ensembl chr  X:139,530,739...139,563,459 		JBrowse link
G FCN2 ficolin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr 9:134,864,144...134,887,523
Ensembl chr 9:134,880,810...134,887,523 		JBrowse link
G FGD6 FYVE, RhoGEF and PH domain containing 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr12:95,076,749...95,217,467
Ensembl chr12:95,076,749...95,217,482 		JBrowse link
G FGF18 fibroblast growth factor 18 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 5:171,419,647...171,457,626
Ensembl chr 5:171,419,647...171,457,626 		JBrowse link
G FGF9 fibroblast growth factor 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr13:21,671,073...21,704,498
Ensembl chr13:21,671,073...21,704,498 		JBrowse link
G FN1 fibronectin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073 		JBrowse link
G FTH1 ferritin heavy chain 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26818092 NCBI chr11:61,964,285...61,967,634
Ensembl chr11:61,959,718...61,967,634 		JBrowse link
G GPR27 G protein-coupled receptor 27 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 3:71,753,855...71,756,496
Ensembl chr 3:71,753,855...71,756,496 		JBrowse link
G GPR37 G protein-coupled receptor 37 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 7:124,743,885...124,765,792
Ensembl chr 7:124,743,885...124,765,792 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 IAGP
EXP		 DNA:deletion:cds (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16697254 PMID:7606714 RGD:7495814 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G HDAC4 histone deacetylase 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 2:239,048,168...239,401,649
NCBI chr 2:239,193,331...239,195,457
Ensembl chr 2:239,048,168...239,401,654 		JBrowse link
G HEPH hephaestin EXP CTD Direct Evidence: marker/mechanism CTD PMID:26818092 NCBI chr  X:66,162,671...66,268,863
Ensembl chr  X:66,162,671...66,268,867 		JBrowse link
G HGF hepatocyte growth factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 7:81,699,010...81,770,047
Ensembl chr 7:81,699,010...81,770,438 		JBrowse link
G HTRA1 HtrA serine peptidase 1 disease_progression IEP protein:increased expression:mesothelium (human) RGD PMID:18681782 RGD:152975625 NCBI chr10:122,461,553...122,514,907
Ensembl chr10:122,458,551...122,514,907 		JBrowse link
G ICAM2 intercellular adhesion molecule 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr17:64,002,595...64,020,633
Ensembl chr17:64,002,594...64,020,634 		JBrowse link
G IFNG interferon gamma EXP CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IGF2BP3 insulin like growth factor 2 mRNA binding protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23621518 NCBI chr 7:23,310,209...23,470,491
Ensembl chr 7:23,310,209...23,470,491 		JBrowse link
G IL12B interleukin 12B EXP CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G IL1A interleukin 1 alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL2RA interleukin 2 receptor subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr10:6,010,689...6,062,367
Ensembl chr10:6,010,689...6,062,370 		JBrowse link
G IL3 interleukin 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 5:132,060,655...132,063,204
Ensembl chr 5:132,060,655...132,063,204 		JBrowse link
G IL4 interleukin 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL6 interleukin 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G ILK integrin linked kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:23045294 NCBI chr11:6,603,774...6,610,870
Ensembl chr11:6,603,708...6,610,874 		JBrowse link
G KAT5 lysine acetyltransferase 5 EXP CTD Direct Evidence: therapeutic CTD PMID:26780987 NCBI chr11:65,712,018...65,719,604
Ensembl chr11:65,711,996...65,719,604 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr 4:54,657,957...54,740,715
Ensembl chr 4:54,657,267...54,740,783 		JBrowse link
G LIMCH1 LIM and calponin homology domains 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 4:41,359,607...41,700,044
Ensembl chr 4:41,359,607...41,700,044 		JBrowse link
G LOC107982234 WT1/WT1-AS bi-directional promoter region IAGP ClinVar Annotator: match by term: Mesothelioma, malignant ClinVar PMID:8621495 PMID:12640141 PMID:16987884 PMID:23349334 PMID:25741868 More... NCBI chr11:32,430,169...32,437,423 JBrowse link
G LTA lymphotoxin alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 6:31,560,610...31,574,324
Ensembl chr 6:31,572,054...31,574,324 		JBrowse link
G MCAM melanoma cell adhesion molecule disease_progression ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:22784439 PMID:23621518 PMID:23621518 RGD:7364782 NCBI chr11:119,308,529...119,317,130
Ensembl chr11:119,308,529...119,321,521 		JBrowse link
G MDK midkine EXP CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr11:46,380,784...46,383,837
Ensembl chr11:46,380,756...46,383,837 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 7:116,672,196...116,798,377
Ensembl chr 7:116,672,196...116,798,377 		JBrowse link
G MIF macrophage migration inhibitory factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227 		JBrowse link
G MIR125A microRNA 125a EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr19:51,693,254...51,693,339
Ensembl chr19:51,693,254...51,693,339 		JBrowse link
G MIR126 microRNA 126 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21483773 NCBI chr 9:136,670,602...136,670,686
Ensembl chr 9:136,670,602...136,670,686 		JBrowse link
G MIR1281 microRNA 1281 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27716620 NCBI chr22:41,092,513...41,092,566
Ensembl chr22:41,092,513...41,092,566 		JBrowse link
G MIR197 microRNA 197 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27716620 NCBI chr 1:109,598,893...109,598,967
Ensembl chr 1:109,598,893...109,598,967 		JBrowse link
G MIR32 microRNA 32 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27716620 NCBI chr 9:109,046,229...109,046,298
Ensembl chr 9:109,046,229...109,046,298 		JBrowse link
G MIR484 microRNA 484 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr16:15,643,294...15,643,372
Ensembl chr16:15,643,294...15,643,372 		JBrowse link
G MLANA melan-A EXP CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr 9:5,890,889...5,910,606
Ensembl chr 9:5,890,889...5,910,606 		JBrowse link
G MSLN mesothelin EXP CTD Direct Evidence: marker/mechanism CTD PMID:19190155 PMID:27032653 NCBI chr16:760,734...768,865
Ensembl chr16:760,734...768,865 		JBrowse link
G MTMR4 myotubularin related protein 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr17:58,489,537...58,519,047
Ensembl chr17:58,489,529...58,517,905 		JBrowse link
G MUC1 mucin 1, cell surface associated EXP CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr 1:155,185,824...155,192,915
Ensembl chr 1:155,185,824...155,192,916 		JBrowse link
G NANOS1 nanos C2HC-type zinc finger 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr10:119,029,714...119,033,730
Ensembl chr10:119,029,714...119,033,730 		JBrowse link
G NAT2 N-acetyltransferase 2 susceptibility IAGP
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16697254 PMID:15993904 RGD:5131858 NCBI chr 8:18,386,301...18,401,218
Ensembl chr 8:18,391,282...18,401,218 		JBrowse link
G NF2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor disease_progression ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:23435014 PMID:26463840 PMID:26678224 PMID:26928227 PMID:29112861 More... RGD:150530636, RGD:150530640 NCBI chr22:29,603,556...29,698,600
Ensembl chr22:29,603,553...29,698,598 		JBrowse link
G NGF nerve growth factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770 		JBrowse link
G OSMR oncostatin M receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 5:38,846,012...38,945,579
Ensembl chr 5:38,845,858...38,945,596 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21543585 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PDPN podoplanin EXP CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr 1:13,583,757...13,617,957
Ensembl chr 1:13,583,465...13,617,957 		JBrowse link
G PLLP plasmolipin EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr16:57,256,097...57,284,672
Ensembl chr16:57,248,547...57,284,672 		JBrowse link
G PTPRF protein tyrosine phosphatase receptor type F EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 1:43,522,051...43,623,666
Ensembl chr 1:43,525,187...43,623,666 		JBrowse link
G PWAR6 Prader Willi/Angelman region RNA 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr15:25,031,873...25,036,490 JBrowse link
G PYCARD PYD and CARD domain containing EXP CTD Direct Evidence: marker/mechanism CTD PMID:26935421 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450 		JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 3:12,583,601...12,664,117
Ensembl chr 3:12,582,101...12,664,201 		JBrowse link
G RXRA retinoid X receptor alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 9:134,326,455...134,440,585
Ensembl chr 9:134,317,098...134,440,585 		JBrowse link
G RYR2 ryanodine receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26928227 NCBI chr 1:237,042,184...237,833,988
Ensembl chr 1:237,042,184...237,833,988 		JBrowse link
G S100B S100 calcium binding protein B EXP CTD Direct Evidence: marker/mechanism CTD PMID:28377727 NCBI chr21:46,598,604...46,605,082
Ensembl chr21:46,598,604...46,605,208 		JBrowse link
G SDC1 syndecan 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27032653 NCBI chr 2:20,200,797...20,225,475
Ensembl chr 2:20,200,797...20,225,433 		JBrowse link
G SEMA4F ssemaphorin 4F EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 2:74,654,247...74,709,713
Ensembl chr 2:74,654,226...74,690,634 		JBrowse link
G SERPINA4 serpin family A member 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr14:94,561,442...94,569,906
Ensembl chr14:94,561,442...94,569,913 		JBrowse link
G SETD2 SET domain containing 2, histone lysine methyltransferase EXP
IAGP		 CTD Direct Evidence: marker/mechanism
DNA:mutations:multiple (human)		 CTD
RGD		 PMID:26928227 PMID:27834213 RGD:150429641 NCBI chr 3:47,016,436...47,164,840
Ensembl chr 3:47,016,428...47,164,113 		JBrowse link
G SETDB1 SET domain bifurcated histone lysine methyltransferase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26928227 NCBI chr 1:150,926,263...150,964,737
Ensembl chr 1:150,926,263...150,964,744 		JBrowse link
G SF3B1 splicing factor 3b subunit 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26928227 NCBI chr 2:197,389,784...197,435,093
Ensembl chr 2:197,388,515...197,435,079 		JBrowse link
G SHBG sex hormone binding globulin EXP CTD Direct Evidence: marker/mechanism CTD PMID:28377727 NCBI chr17:7,614,064...7,633,372
Ensembl chr17:7,613,946...7,633,382 		JBrowse link
G SLC22A5 solute carrier family 22 member 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 5:132,369,710...132,395,612
Ensembl chr 5:132,369,710...132,395,613 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893 		JBrowse link
G SMARCA2 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 9:2,015,347...2,193,620
Ensembl chr 9:1,980,290...2,193,624 		JBrowse link
G SOD2 superoxide dismutase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20617513 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G TBL1XR1 TBL1X/Y related 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 3:177,019,344...177,201,800
Ensembl chr 3:177,019,340...177,228,000 		JBrowse link
G TF transferrin EXP CTD Direct Evidence: marker/mechanism CTD PMID:26818092 NCBI chr 3:133,661,998...133,796,641
Ensembl chr 3:133,746,040...133,796,641 		JBrowse link
G TFDP2 transcription factor Dp-2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 3:141,944,428...142,149,544
Ensembl chr 3:141,944,428...142,149,544 		JBrowse link
G TGFB2 transforming growth factor beta 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619 		JBrowse link
G TNFRSF8 TNF receptor superfamily member 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr 1:12,063,303...12,144,207
Ensembl chr 1:12,063,303...12,144,207 		JBrowse link
G TP53 tumor protein p53 EXP
ISO		 CTD Direct Evidence: marker/mechanism CTD PMID:26928227 PMID:37441092 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TRAF7 TNF receptor associated factor 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26928227 NCBI chr16:2,155,782...2,178,129
Ensembl chr16:2,155,698...2,178,129 		JBrowse link
G TXN thioredoxin EXP CTD Direct Evidence: marker/mechanism CTD PMID:27032653 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507 		JBrowse link
G ULK2 unc-51 like autophagy activating kinase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26928227 NCBI chr17:19,770,830...19,867,936
Ensembl chr17:19,770,829...19,867,936 		JBrowse link
G VIM vimentin EXP CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
G WNT3 Wnt family member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr17:46,762,506...46,818,692
Ensembl chr17:46,762,506...46,833,154 		JBrowse link
G WT1 WT1 transcription factor IAGP
EXP		 ClinVar Annotator: match by term: Mesothelioma, malignant
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD		 PMID:1302008 PMID:1327525 PMID:1338906 PMID:1655284 PMID:1658787 More... NCBI chr11:32,387,775...32,435,539
Ensembl chr11:32,387,775...32,435,564 		JBrowse link
G WWC1 WW and C2 domain containing 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 5:168,291,645...168,472,303
Ensembl chr 5:168,291,645...168,472,303 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 treatment IAGP RGD PMID:22982660 RGD:151347428 NCBI chr19:43,543,311...43,575,527
Ensembl chr19:43,543,311...43,580,473 		JBrowse link
malignant pleural mesothelioma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAP1 BRCA1 associated deubiquitinase 1 disease_progression IEP RGD PMID:27422796 RGD:127229946 NCBI chr 3:52,401,008...52,410,008
Ensembl chr 3:52,401,008...52,410,008 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 exacerbates HEP mRNA:increased expression:pleura, lung (human) RGD PMID:17253596 RGD:153344528 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636 		JBrowse link
G BIRC7 baculoviral IAP repeat containing 7 ameliorates HEP mRNA:increased expression:pleura, lung (human) RGD PMID:17253596 RGD:153344528 NCBI chr20:63,235,905...63,240,495
Ensembl chr20:63,235,883...63,240,495 		JBrowse link
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit ameliorates IMP RGD PMID:18722110 RGD:151667912 NCBI chr15:32,030,483...32,173,018
Ensembl chr15:31,923,438...32,173,018 		JBrowse link
G CSF1R colony stimulating factor 1 receptor HEP mRNA:increased expression:peritoneum�� (human) RGD PMID:24722292 RGD:150524278 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372 		JBrowse link
G EMX2 empty spiracles homeobox 2 exacerbates IEP mRNA:decreased expression:mesothelium of pleural cavity (human) RGD PMID:25023662 RGD:153323312 NCBI chr10:117,542,746...117,549,546
Ensembl chr10:117,542,445...117,549,546 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit disease_progression IEP mRNA, protein:increased expression:pleura RGD PMID:22028491 RGD:126781718 NCBI chr 7:148,807,383...148,884,291
Ensembl chr 7:148,807,257...148,884,321 		JBrowse link
G IL7R interleukin 7 receptor disease_progression IEP RGD PMID:26155428 RGD:151347688 NCBI chr 5:35,856,891...35,879,603
Ensembl chr 5:35,852,695...35,879,603 		JBrowse link
G KDM6A lysine demethylase 6A IEP mRNA:increased expression:mesothelium of pleural cavity (human) RGD PMID:28197626 RGD:150429737 NCBI chr  X:44,873,188...45,112,779
Ensembl chr  X:44,873,188...45,112,779 		JBrowse link
G MIR192 microRNA 192 IEP miRNA:decreased expression:pleura (human) RGD PMID:26125439 RGD:11529530 NCBI chr11:64,891,137...64,891,246
Ensembl chr11:64,891,137...64,891,246 		JBrowse link
G MIR193A microRNA 193a IEP miRNA:decreased expression:pleura (human) RGD PMID:26125439 RGD:11529530 NCBI chr17:31,559,996...31,560,083
Ensembl chr17:31,559,996...31,560,083 		JBrowse link
G MIR200B microRNA 200b IEP miRNA:decreased expression:pleura (human) RGD PMID:26125439 RGD:11529530 NCBI chr 1:1,167,104...1,167,198
Ensembl chr 1:1,167,104...1,167,198 		JBrowse link
G MLH1 mutL homolog 1 disease_progression IEP RGD PMID:23810210 RGD:126848799 NCBI chr 3:36,993,466...37,050,846
Ensembl chr 3:36,993,226...37,050,896 		JBrowse link
G NCOA2 nuclear receptor coactivator 2 ameliorates IEP protein:increased expression:mesothelium of pleural cavity (human) RGD PMID:22011668 RGD:153002578 NCBI chr 8:70,109,782...70,456,446
Ensembl chr 8:70,109,782...70,403,808 		JBrowse link
G NF2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor disease_progression IEP
IAGP		 DNA:loss of heterozygosity RGD PMID:27378628 PMID:26928227 PMID:26493618 RGD:150530638, RGD:150429647, RGD:11553131 NCBI chr22:29,603,556...29,698,600
Ensembl chr22:29,603,553...29,698,598 		JBrowse link
G RAD21 RAD21 cohesin complex component HEP RGD PMID:19380173 RGD:150520037 NCBI chr 8:116,845,934...116,874,776
Ensembl chr 8:116,845,934...116,874,776 		JBrowse link
G SETD2 SET domain containing 2, histone lysine methyltransferase disease_progression IAGP
IEP		 DNA:mutations:CDS:multiple (human) RGD PMID:26928227 PMID:33691361 RGD:150429647, RGD:150520202 NCBI chr 3:47,016,436...47,164,840
Ensembl chr 3:47,016,428...47,164,113 		JBrowse link
G SLC7A5 solute carrier family 7 member 5 disease_progression IEP protein:increased expression:pleura RGD PMID:22199264 PMID:24912849 RGD:151361201, RGD:151660330 NCBI chr16:87,830,023...87,869,507
Ensembl chr16:87,830,016...87,869,507 		JBrowse link
G SMO smoothened, frizzled class receptor disease_progression IEP
IAGP		 DNA:missense mutations RGD PMID:23379358 PMID:33209614 RGD:150521620, RGD:150521621 NCBI chr 7:129,188,633...129,213,545
Ensembl chr 7:129,188,633...129,213,545 		JBrowse link
G XIAP X-linked inhibitor of apoptosis ameliorates HEP mRNA:increased expression:pleura, lung (human) RGD PMID:17253596 RGD:153344528 NCBI chr  X:123,859,708...123,913,972
Ensembl chr  X:123,859,712...123,913,972 		JBrowse link
maxillary sinus squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN1A cyclin dependent kinase inhibitor 1A IEP RGD PMID:15040115 RGD:8662355 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
Multiple Self-healing Palmoplantar Carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NLRP1 NLR family pyrin domain containing 1 IAGP ClinVar Annotator: match by term: Palmoplantar carcinoma, multiple self-healing ClinVar
OMIM		 PMID:16199547 PMID:17377159 PMID:23349227 PMID:24033266 PMID:25050600 More... NCBI chr17:5,501,396...5,584,509
Ensembl chr17:5,499,415...5,619,424 		JBrowse link
oral squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase severity IAGP DNA:mutations RGD PMID:16676365 RGD:126925209 NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,043...130,887,675 		JBrowse link
G ADA adenosine deaminase disease_progression IEP RGD PMID:27221867 RGD:152995268 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252 		JBrowse link
G AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 disease_progression IEP RGD PMID:26464646 RGD:11526681 NCBI chr12:57,723,761...57,742,161
Ensembl chr12:57,723,761...57,742,157 		JBrowse link
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 IEP protein:increased expression:oral epithelium RGD PMID:30981761 RGD:597538586 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442 		JBrowse link
G ANGPT1 angiopoietin 1 HEP protein:decreased expression:oral mucosa (human) RGD PMID:26044849 RGD:153323290 NCBI chr 8:107,249,482...107,497,918
Ensembl chr 8:107,249,482...107,498,055 		JBrowse link
G ANGPT2 angiopoietin 2 HEP protein:increased expression:oral mucosa (human) RGD PMID:26044849 RGD:153323290 NCBI chr 8:6,499,632...6,563,245
Ensembl chr 8:6,499,632...6,563,409 		JBrowse link
G ARID2 AT-rich interaction domain 2 disease_progression IEP RGD PMID:31918270 RGD:150340710 NCBI chr12:45,729,706...45,908,037
Ensembl chr12:45,729,706...45,908,040 		JBrowse link
G ARPC1B actin related protein 2/3 complex subunit 1B severity IEP protein:increased expression:oral mucosa (human) RGD PMID:26138391 RGD:11046268 NCBI chr 7:99,374,259...99,394,816
Ensembl chr 7:99,374,249...99,394,816 		JBrowse link
G ATM ATM serine/threonine kinase disease_progression IEP protein:increased expression:mucosa of oral region (human) RGD PMID:29928356 PMID:18288488 RGD:150340604, RGD:150340709 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102 		JBrowse link
G ATP6V1C1 ATPase H+ transporting V1 subunit C1 IEP RGD PMID:26984774 RGD:14700648 NCBI chr 8:103,021,083...103,073,051
Ensembl chr 8:103,021,063...103,073,051 		JBrowse link
G AXIN1 axin 1 disease_progression IEP protein:decreased expression:oral epithelium (human)
mRNA:increased expression:oral epithelium (human)		 RGD PMID:17143481 PMID:21393552 RGD:150530474, RGD:150530486 NCBI chr16:287,440...352,723
Ensembl chr16:287,440...352,723 		JBrowse link
G AXIN2 axin 2 susceptibility
ameliorates
disease_progression		 IAGP
IMP
IEP		 DNA:SNP:intron: C>T (rs3923087)(human) RGD PMID:21393552 PMID:33046030 PMID:33046030 RGD:150530486, RGD:151356656, RGD:151356656 NCBI chr17:65,528,563...65,561,648
Ensembl chr17:65,528,563...65,561,648 		JBrowse link
G AZGP1 alpha-2-glycoprotein 1, zinc-binding IEP protein:increased expression:saliva
protein:decreased expression:saliva		 RGD PMID:29199150 PMID:33564003 RGD:153350131, RGD:153350144 NCBI chr 7:99,966,730...99,976,031
Ensembl chr 7:99,966,720...99,976,042 		JBrowse link
G BARHL2 BarH like homeobox 2 IDA
IEP		 protein:decreased expression:mouth mucosa RGD PMID:27542258 PMID:27542258 RGD:14390167, RGD:14390167 NCBI chr 1:90,711,539...90,717,302
Ensembl chr 1:90,711,539...90,717,302 		JBrowse link
G BCL2L1 BCL2 like 1 IEP mRNA, protein:increased expression:mouth (human) RGD PMID:34111459 RGD:153344573 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BHLHE41 basic helix-loop-helix family member e41 treatment IEP Human cells in mouse model RGD PMID:27602964 RGD:151665310 NCBI chr12:26,120,030...26,125,037
Ensembl chr12:26,120,030...26,125,037 		JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 IEP protein:increased expression:oral cavity (human) RGD PMID:20967871 RGD:152999012 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 disease_progression
ameliorates		 IEP protein:increased expression:oral cavity (human)
mRNA:increased expression:oral cavity (human)
protein:decreased expression:oral cavity (human)		 RGD PMID:23852810 PMID:20967871 PMID:29286141 PMID:21952624 RGD:152998980, RGD:152999012, RGD:152999009, RGD:152998987 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 IEP protein:increased expression:oral cavity (human) RGD PMID:20967871 RGD:152999012 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636 		JBrowse link
G BRINP2 BMP/retinoic acid inducible neural specific 2 IAGP DNA:amplication:oral epithelium RGD PMID:21334929 RGD:14398483 NCBI chr 1:177,170,958...177,282,422
Ensembl chr 1:177,170,958...177,282,422 		JBrowse link
G BST2 bone marrow stromal cell antigen 2 disease_progression IEP RGD PMID:24706327 RGD:14398491 NCBI chr19:17,402,939...17,405,630
Ensembl chr19:17,402,939...17,405,630 		JBrowse link
G BTK Bruton tyrosine kinase treatment HEP mRNA:increased expression:oral epithelium (human) RGD PMID:33640903 RGD:151347851 NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,338...101,390,796 		JBrowse link
G CA12 carbonic anhydrase 12 disease_progression HEP RGD PMID:22172588 RGD:153352330 NCBI chr15:63,321,378...63,381,846
Ensembl chr15:63,321,378...63,381,846 		JBrowse link
G CALR calreticulin exacerbates IEP
HEP		 protein:increased expression:oral epithelium (human)
protein:increased expression:mouth (human)		 RGD PMID:28599487 PMID:23375593 RGD:150520158, RGD:150521688 NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489 		JBrowse link
G CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 IEP RGD PMID:30205384 RGD:18337270 NCBI chr 1:20,482,391...20,486,210
Ensembl chr 1:20,482,391...20,486,210 		JBrowse link
G CBX2 chromobox 2 disease_progression IEP RGD PMID:24885002 RGD:9586732 NCBI chr17:79,777,311...79,787,983
Ensembl chr17:79,778,148...79,787,983 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 susceptibility
disease_progression		 IAGP
ISO		 DNA:polymorphism,haplotype::2518A>G(human)
associated with social isolation;protein:increased expression:tongue (rat)		 RGD PMID:21883707 PMID:33411841 RGD:8661694, RGD:152998999 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 susceptibility IAGP DNA:polymorphism,haplotype:cds:p.V64I(human) RGD PMID:21883707 RGD:8661694 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940 		JBrowse link
G CDC73 cell division cycle 73 IEP mRNA:altered expression: tongue, oral cavity (human) RGD PMID:24257751 RGD:150537040 NCBI chr 1:193,122,031...193,254,815
Ensembl chr 1:193,121,983...193,254,815 		JBrowse link
G CDH1 cadherin 1 disease_progression IEP RGD PMID:26464646 RGD:11526681 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A susceptibility
no_association
disease_progression		 IAGP
IEP		 DNA:polymorphism:exon:149A>G(human)
DNA:polymorphism: :98C>A(human)		 RGD PMID:10873097 PMID:18251939 PMID:15817070 PMID:10873097 RGD:8662371, RGD:8662395, RGD:8662374, RGD:8662371 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G CERS1 ceramide synthase 1 exacerbates ISO RGD PMID:33753723 RGD:156431057 NCBI chr19:18,868,545...18,896,982
Ensembl chr19:18,868,545...18,896,727 		JBrowse link
G CHAF1B chromatin assembly factor 1 subunit B disease_progression IEP protein:increased expression:mouth mucosa: RGD PMID:22882088 RGD:9587477 NCBI chr21:36,385,392...36,419,015
Ensembl chr21:36,385,392...36,419,015 		JBrowse link
G CLPTM1L CLPTM1 like susceptibility IAGP DNA:SNP: :rs402710(human) RGD PMID:28025427 RGD:150530487 NCBI chr 5:1,317,752...1,345,099
Ensembl chr 5:1,317,752...1,345,099 		JBrowse link
G CTNND1 catenin delta 1 disease_progression IEP RGD PMID:26464646 RGD:11526681 NCBI chr11:57,761,802...57,819,540
Ensembl chr11:57,753,243...57,819,546 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 IAGP RGD PMID:22660220 RGD:14700952 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 susceptibility IAGP DNA:SNP:exon: (rs2296241) (human) RGD PMID:22612324 RGD:151665337 NCBI chr20:54,143,538...54,173,986
Ensembl chr20:54,153,446...54,173,986 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 IAGP RGD PMID:22954124 RGD:14700880 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G DAXX death domain associated protein ameliorates IMP human cell line in a mouse model RGD PMID:26205068 RGD:152025200 NCBI chr 6:33,318,558...33,322,959
Ensembl chr 6:33,318,558...33,323,016 		JBrowse link
G DDR1 discoidin domain receptor tyrosine kinase 1 IEP mRNA, protein:increased expression:mouth (human) RGD PMID:31253192 RGD:151347620 NCBI chr 6:30,880,970...30,900,156
Ensembl chr 6:30,876,421...30,900,156 		JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 severity IDA RGD PMID:29945346 RGD:150429700 NCBI chr 1:162,630,863...162,787,405
Ensembl chr 1:162,631,373...162,787,405 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta disease_progression IEP
IMP		 RGD PMID:24625449 PMID:24625449 RGD:9589120, RGD:9589120 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359 		JBrowse link
G DOCK6 dedicator of cytokinesis 6 disease_progression IEP RGD PMID:34742001 RGD:155791563 NCBI chr19:11,199,295...11,262,524
Ensembl chr19:11,199,295...11,262,524 		JBrowse link
G EFNB2 ephrin B2 HEP protein:increased expression:oral mucosa (human) RGD PMID:26044849 RGD:153323290 NCBI chr13:106,489,745...106,535,662
Ensembl chr13:106,489,745...106,535,662 		JBrowse link
G EGFR epidermal growth factor receptor IEP RGD PMID:11673832 RGD:126781761 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 IEP RGD PMID:11673832 RGD:126781761 NCBI chr17:39,688,094...39,728,658
Ensembl chr17:39,687,914...39,730,426 		JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 disease_progression IEP RGD PMID:14595263 RGD:126781770 NCBI chr 2:211,375,717...212,538,802
Ensembl chr 2:211,375,717...212,538,841 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit susceptibility IEP
IAGP		 associated with oral mucosa leukoplakia
DNA:SNPs, haplotypes: :multiple		 RGD PMID:24122997 PMID:21697275 PMID:26807327 RGD:126779588, RGD:126781699, RGD:126779606 NCBI chr 7:148,807,383...148,884,291
Ensembl chr 7:148,807,257...148,884,321 		JBrowse link
G FAT1 FAT atypical cadherin 1 onset ISO
IAGP		 protein:increased expression:tongue (mouse)
DNA:mutations:multiple		 RGD PMID:30624777 PMID:28435450 RGD:151347668, RGD:151347687 NCBI chr 4:186,587,794...186,726,696
Ensembl chr 4:186,587,794...186,726,722 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 IAGP associated with human papillomavirus;DNA:missense mutation:cds: p.S249C (human) RGD PMID:30563911 RGD:38500239 NCBI chr 4:1,793,293...1,808,867
Ensembl chr 4:1,793,293...1,808,872 		JBrowse link
G FGFR4 fibroblast growth factor receptor 4 severity IAGP DNA:SNP:exon 9: p.G388R (human) RGD PMID:20127014 RGD:150520164 NCBI chr 5:177,086,915...177,098,144
Ensembl chr 5:177,086,905...177,098,144 		JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 HDA
IEP		 mRNA:decreased expression:oral epithelium (human) RGD PMID:32048621 PMID:32048621 RGD:149735374, RGD:149735374 NCBI chr13:28,003,274...28,100,576
Ensembl chr13:28,003,274...28,100,592 		JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit IEP mRNA, protein:increased expression:mouth (human) RGD PMID:34111459 RGD:153344573 NCBI chr 2:28,392,858...28,417,317
Ensembl chr 2:28,392,448...28,417,317 		JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase ISO RGD PMID:27375172 RGD:13792673 NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374 		JBrowse link
G GPX1 glutathione peroxidase 1 exacerbates HEP protein:increased expression:oral cavity (human) RGD PMID:28653098 RGD:152995473 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GPX4 glutathione peroxidase 4 disease_progression HEP protein:increased expression:oral cavity (human) RGD PMID:28653098 RGD:152995473 NCBI chr19:1,103,994...1,106,779
Ensembl chr19:1,103,982...1,106,791 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta susceptibility IAGP DNA:SNP:intron: (rs9879992) (human) RGD PMID:21393552 RGD:150530486 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 severity IAGP DNA:deletion: : (human) RGD PMID:22213390 PMID:14662415 RGD:12792245, RGD:14700962 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 IEP mRNA,protein:decreased expression:mucosa: RGD PMID:16982972 RGD:10755432 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G H2AX H2A.X variant histone disease_progression IEP protein:increased expression:mucosa of oral region (human) RGD PMID:29928356 RGD:150340604 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465 		JBrowse link
G HES1 hes family bHLH transcription factor 1 ISO protein:increased expression:tongue (mouse) RGD PMID:30624777 RGD:151347668 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732 		JBrowse link
G HP haptoglobin IEP protein:increased expression:saliva RGD PMID:29199150 RGD:153350131 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055 		JBrowse link
G IL10 interleukin 10 susceptibility IAGP DNA:SNP:promoter:-592A>C (human) RGD PMID:28157558 RGD:14975130 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 IEP RGD PMID:19065664 RGD:8549498 NCBI chr  X:115,003,982...115,017,616
Ensembl chr  X:115,003,975...115,019,977 		JBrowse link
G IL1B interleukin 1 beta disease_progression ISO associated with social isolation;protein:increased expression:tongue (rat) RGD PMID:33411841 RGD:152998999 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL2 interleukin 2 IDA RGD PMID:10389944 RGD:8662949 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL6 interleukin 6 disease_progression IEP RGD PMID:24625449 RGD:9589120 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit IEP mRNA, protein:increased expression:mouth (human) RGD PMID:34111459 RGD:153344573 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit IEP associated with papillomavirus infectious disease;protein:increased expression:oral cavity (human) RGD PMID:28155253 RGD:151347666 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315 		JBrowse link
G KMT2D lysine methyltransferase 2D severity IEP RGD PMID:31660637 RGD:150521713 NCBI chr12:49,018,978...49,060,794
Ensembl chr12:49,018,975...49,060,794 		JBrowse link
G MCPH1 microcephalin 1 IEP mRNA:protein:decreased expression:oral cavity, tissue (human) RGD PMID:23472065 RGD:9589036 NCBI chr 8:6,406,627...6,648,508
Ensembl chr 8:6,406,592...6,648,508 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase IEP protein:increased expression, altered expression:mouth mucosa: RGD PMID:20662906 RGD:8548617 NCBI chr 7:116,672,196...116,798,377
Ensembl chr 7:116,672,196...116,798,377 		JBrowse link
G MIR155 microRNA 155 disease_progression IEP RGD PMID:30194167 PMID:28413645 PMID:29909906 RGD:21079420, RGD:24922225, RGD:21079468 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044 		JBrowse link
G MIR187 microRNA 187 IEP RNA:increased expression:plasma RGD PMID:27542258 RGD:14390167 NCBI chr18:35,904,818...35,904,926
Ensembl chr18:35,904,818...35,904,926 		JBrowse link
G MIR20A microRNA 20a IEP RGD PMID:26781875 RGD:26884343 NCBI chr13:91,351,065...91,351,135
Ensembl chr13:91,351,065...91,351,135 		JBrowse link
G MIR221 microRNA 221 exacerbates IDA RGD PMID:21226887 RGD:151708999 NCBI chr  X:45,746,157...45,746,266
Ensembl chr  X:45,746,157...45,746,266 		JBrowse link
G MIR222 microRNA 222 disease_progression
exacerbates		 IEP
IDA		 RGD PMID:31841247 PMID:21226887 RGD:151708741, RGD:151708999 NCBI chr  X:45,747,015...45,747,124
Ensembl chr  X:45,747,015...45,747,124 		JBrowse link
G MIR31 microRNA 31 treatment IEP RGD PMID:20233326 RGD:153297767 NCBI chr 9:21,512,115...21,512,185
Ensembl chr 9:21,512,115...21,512,185 		JBrowse link
G MIR585 microRNA 585 IEP mRNA:altered expression:oral mucosa (human) RGD PMID:21795477 RGD:152995504 NCBI chr 5:169,263,601...169,263,694
Ensembl chr 5:169,263,601...169,263,694 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase susceptibility IAGP DNA:missense mutation:cds:677C>T (human) RGD PMID:16365753 RGD:10449416 NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455 		JBrowse link
G NAIP NLR family apoptosis inhibitory protein IEP protein:increased expression:oral cavity (human) RGD PMID:20967871 RGD:152999012 NCBI chr 5:70,968,166...71,025,339
Ensembl chr 5:70,968,166...71,025,339 		JBrowse link
G NOTCH1 notch receptor 1 ISO protein:increased expression:tongue (mouse) RGD PMID:30624777 RGD:151347668 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048 		JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 HEP protein:decreased expression:oral mucosa (human) RGD PMID:26044849 RGD:153323290 NCBI chr17:64,319,415...64,390,860
Ensembl chr17:64,319,415...64,413,776 		JBrowse link
G PLAU plasminogen activator, urokinase severity IEP protein:increased expression:oral mucosa (rat) RGD PMID:15878520 RGD:8547730 NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496 		JBrowse link
G PLCG1 phospholipase C gamma 1 disease_progression
ameliorates		 IEP protein:decreased expression:oral cavity (human) RGD PMID:26464646 PMID:25085076 RGD:11526681, RGD:151356936 NCBI chr20:41,137,543...41,177,626
Ensembl chr20:41,136,960...41,196,801 		JBrowse link
G PRDX2 peroxiredoxin 2 IEP protein:increased expression:saliva RGD PMID:29199150 RGD:153350131 NCBI chr19:12,796,823...12,801,800
Ensembl chr19:12,796,820...12,801,800 		JBrowse link
G PTEN phosphatase and tensin homolog disease_progression IEP protein:increased expression:oral epithelium (human) RGD PMID:33109573 RGD:127285606 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G PTGIS prostaglandin I2 synthase IEP mRNA,protein:decreased expression:mouth mucosa (human) RGD PMID:30532780 RGD:151347832 NCBI chr20:49,503,874...49,568,137
Ensembl chr20:49,503,874...49,568,137 		JBrowse link
G PTPN13 protein tyrosine phosphatase non-receptor type 13 treatment IEP RGD PMID:21176871 RGD:152600900 NCBI chr 4:86,594,315...86,815,161
Ensembl chr 4:86,594,315...86,815,171 		JBrowse link
G RAD21 RAD21 cohesin complex component exacerbates IEP mRNA:decreased expression:oral cavity (human) RGD PMID:16416296 RGD:150520028 NCBI chr 8:116,845,934...116,874,776
Ensembl chr 8:116,845,934...116,874,776 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit IEP protein:increased expression:mouth (human) RGD PMID:34111459 RGD:153344573 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G SERPINE1 serpin family E member 1 severity
disease_progression		 IEP protein:increased expression:oral mucosa (rat) RGD PMID:15878520 PMID:24999729 RGD:8547730, RGD:13208508 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SKP2 S-phase kinase associated protein 2 IEP protein:increased expression:mucosa of oral region (human) RGD PMID:24743017 RGD:151665336 NCBI chr 5:36,152,111...36,193,530
Ensembl chr 5:36,151,989...36,196,849 		JBrowse link
G SLC7A5 solute carrier family 7 member 5 severity IEP RGD PMID:23801167 RGD:151361213 NCBI chr16:87,830,023...87,869,507
Ensembl chr16:87,830,016...87,869,507 		JBrowse link
G SOX2 SRY-box transcription factor 2 IEP protein:increased expression:oral epithelium RGD PMID:30981761 RGD:597538586 NCBI chr 3:181,711,925...181,714,436
Ensembl chr 3:181,711,925...181,714,436 		JBrowse link
G TERT telomerase reverse transcriptase susceptibility IAGP DNA:SNPs: :rs2736100,rs2736098(human) RGD PMID:28025427 RGD:150530487 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068 		JBrowse link
G TET2 tet methylcytosine dioxygenase 2 IEP protein:decreased expression:oral epithelium (human) RGD PMID:24122999 RGD:150429611 NCBI chr 4:105,145,875...105,279,803
Ensembl chr 4:105,145,875...105,279,816 		JBrowse link
G TNF tumor necrosis factor disease_progression ISO associated with social isolation;protein:increased expression:tongue (rat) RGD PMID:33411841 RGD:152998999 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TP53 tumor protein p53 IAGP
ISO		 DNA:missense mutations: :multiple
protein:increased expression:mouth (human)		 RGD PMID:27283772 PMID:34111459 RGD:14995497, RGD:153344573 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TTR transthyretin IEP protein:increased expression:saliva (human) RGD PMID:23784731 RGD:151664609 NCBI chr18:31,591,877...31,598,821
Ensembl chr18:31,557,009...31,598,833 		JBrowse link
G VEGFA vascular endothelial growth factor A HEP protein:increased expression:oral mucosa (human) RGD PMID:26044849 RGD:153323290 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G WNT11 Wnt family member 11 susceptibility IAGP DNA:SNP:exon: A>G (rs1533767) (human) RGD PMID:21393552 RGD:150530486 NCBI chr11:76,186,325...76,210,761
Ensembl chr11:76,186,325...76,210,736 		JBrowse link
Palmoplantar Hyperkeratosis with Squamous Cell Carcinoma of Skin and Sex Reversal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RSPO1 R-spondin 1 IAGP
EXP		 ClinVar Annotator: match by term: Palmoplantar hyperkeratosis with squamous cell carcinoma of skin and 46,XX sex reversal
ClinVar Annotator: match by term: RSPO1-related condition
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:16158431 PMID:17041600 PMID:25741868 PMID:28492532 NCBI chr 1:37,611,350...37,634,892
Ensembl chr 1:37,611,350...37,634,892 		JBrowse link
pancreatic adenosquamous carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TGFB2 transforming growth factor beta 2 ameliorates IMP human cells in a mouse model RGD PMID:21366804 RGD:155630611 NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619 		JBrowse link
papillary carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KISS1R KISS1 receptor IEP RGD PMID:11994395 RGD:1599280 NCBI chr19:917,333...921,005
Ensembl chr19:917,287...921,005 		JBrowse link
G VEGFC vascular endothelial growth factor C disease_progression IEP associated with thyroid diseases;mRNA:increased expression:thyroid gland: RGD PMID:12203051 RGD:7483611 NCBI chr 4:176,683,538...176,792,922
Ensembl chr 4:176,683,538...176,792,922 		JBrowse link
papillary renal cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIRC3 baculoviral IAP repeat containing 3 exacerbates HEP mRNA:increased expression:kidney (human) RGD PMID:31964418 RGD:153344516 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 disease_progression HEP mRNA:increased expression:kidney (human) RGD PMID:31964418 RGD:153344516 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase IAGP OMIM NCBI chr 7:116,672,196...116,798,377
Ensembl chr 7:116,672,196...116,798,377 		JBrowse link
G MIR210 microRNA 210 IEP miRNA:increased expression:kidney (human) RGD PMID:23449350 RGD:155260320 NCBI chr11:568,089...568,198
Ensembl chr11:568,089...568,198 		JBrowse link
G PRCC proline rich mitotic checkpoint control factor IAGP OMIM NCBI chr 1:156,767,535...156,800,815
Ensembl chr 1:156,750,610...156,800,815 		JBrowse link
G XIAP X-linked inhibitor of apoptosis exacerbates HEP mRNA:increased expression:kidney (human) RGD PMID:31964418 RGD:153344516 NCBI chr  X:123,859,708...123,913,972
Ensembl chr  X:123,859,712...123,913,972 		JBrowse link
papilloma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCND1 cyclin D1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12151359 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A IEP
EXP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:12151359 PMID:11684723 PMID:10430900 RGD:8662351, RGD:8662432 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G EGFR epidermal growth factor receptor susceptibility ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:8603490 PMID:10943841 RGD:734919 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:8603490 NCBI chr17:39,688,094...39,728,658
Ensembl chr17:39,687,914...39,730,426 		JBrowse link
G HRAS HRas proto-oncogene, GTPase EXP CTD Direct Evidence: marker/mechanism CTD PMID:8330346 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321 		JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 ISO RGD PMID:20610622 RGD:7495823 NCBI chr17:12,020,877...12,143,828
Ensembl chr17:12,020,829...12,143,830 		JBrowse link
G MMP2 matrix metallopeptidase 2 treatment ISO associated with Skin Neoplasms RGD PMID:20619141 RGD:8657035 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:9496914 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G ODC1 ornithine decarboxylase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17928125 NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327 		JBrowse link
G PLA2G4A phospholipase A2 group IVA ISO associated with Bladder Neoplasms;mRNA:increased expression:bladder RGD PMID:16621493 RGD:1642457 NCBI chr 1:186,828,949...186,988,981
Ensembl chr 1:186,828,949...186,988,981 		JBrowse link
G PTGES prostaglandin E synthase ISO mRNA:increased expression:urinary bladder RGD PMID:16621493 RGD:1642457 NCBI chr 9:129,738,349...129,753,042
Ensembl chr 9:129,738,331...129,753,042 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12151359 PMID:16144915 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G SOD2 superoxide dismutase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:11507057 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SPRR1A small proline rich protein 1A EXP CTD Direct Evidence: marker/mechanism CTD PMID:8617999 NCBI chr 1:152,984,081...152,985,814
Ensembl chr 1:152,984,081...152,985,814 		JBrowse link
G TGFA transforming growth factor alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:8603490 NCBI chr 2:70,447,284...70,553,826
Ensembl chr 2:70,447,284...70,554,193 		JBrowse link
G TGFB1 transforming growth factor beta 1 disease_progression ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20172950 PMID:7954410 RGD:7394796 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TYR tyrosinase treatment ISO RGD PMID:15007389 RGD:8694346 NCBI chr11:89,177,875...89,295,759
Ensembl chr11:89,177,875...89,295,759 		JBrowse link
peritoneal mesothelioma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LATS1 large tumor suppressor kinase 1 IAGP ClinVar Annotator: match by term: Malignant peritoneal mesothelioma ClinVar NCBI chr 6:149,658,153...149,718,101
Ensembl chr 6:149,658,153...149,718,105 		JBrowse link
G LATS2 large tumor suppressor kinase 2 IAGP ClinVar Annotator: match by term: Malignant peritoneal mesothelioma ClinVar NCBI chr13:20,973,036...21,061,586
Ensembl chr13:20,973,036...21,061,586 		JBrowse link
G MECOM MDS1 and EVI1 complex locus IAGP ClinVar Annotator: match by term: Malignant peritoneal mesothelioma ClinVar NCBI chr 3:169,083,507...169,663,712
Ensembl chr 3:169,083,499...169,663,775 		JBrowse link
G TRAF7 TNF receptor associated factor 7 IAGP DNA:missense mutations:multiple RGD PMID:30171198 RGD:151356964 NCBI chr16:2,155,782...2,178,129
Ensembl chr16:2,155,698...2,178,129 		JBrowse link
pharynx squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLPTM1L CLPTM1 like sexual_dimorphism IAGP in males;DNA:SNP: :rs401681(human) RGD PMID:31429604 RGD:150530637 NCBI chr 5:1,317,752...1,345,099
Ensembl chr 5:1,317,752...1,345,099 		JBrowse link
sarcomatoid mesothelioma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN2A cyclin dependent kinase inhibitor 2A ISO DNA:deletion RGD PMID:20065947 RGD:7248760 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301 		JBrowse link
seborrheic keratosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 IEP RGD PMID:8919037 RGD:7421562 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,629 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 IAGP ClinVar Annotator: match by term: Keratosis Seborrheica ClinVar PMID:1908846 PMID:7773297 PMID:8589699 PMID:8640234 PMID:8858131 More... NCBI chr 4:1,793,293...1,808,867
Ensembl chr 4:1,793,293...1,808,872 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha IAGP
EXP		 ClinVar Annotator: match by term: Keratosis Seborrheica | ClinVar Annotator: match by term: Seborrheic keratosis
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD		 PMID:15016963 PMID:15520168 PMID:15608678 PMID:15930273 PMID:17376864 More... NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093 		JBrowse link
skin papilloma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL20 C-C motif chemokine ligand 20 IEP protein:decreased expression:skin RGD PMID:21715145 RGD:7483622 NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564 		JBrowse link
G CLU clusterin ISO RGD PMID:11085517 RGD:8746700 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700 		JBrowse link
G FGF10 fibroblast growth factor 10 ISO protein:increased expression:skin (mouse) RGD PMID:24582960 RGD:126928134 NCBI chr 5:44,300,247...44,389,420
Ensembl chr 5:44,300,247...44,389,706 		JBrowse link
G MIR21 microRNA 21 ameliorates ISO RGD PMID:21646541 RGD:41404663 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G NRG1 neuregulin 1 HEP DNA:hypermethylation: RGD PMID:31892232 RGD:39456089 NCBI chr 8:31,639,245...32,774,046
Ensembl chr 8:31,639,222...32,855,666 		JBrowse link
G TLR2 toll like receptor 2 IEP protein:increased expression,altered expression:cytoplasm,membrane, nucleus: RGD PMID:24617037 RGD:8553046 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260 		JBrowse link
skin squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTCF CCCTC-binding factor IAGP DNA:mutations:multiple (human) RGD PMID:27974201 RGD:151356739 NCBI chr16:67,562,526...67,639,185
Ensembl chr16:67,562,467...67,639,177 		JBrowse link
G DDX5 DEAD-box helicase 5 IEP protein:increased expression:foreskin (human) RGD PMID:22548649 RGD:9850272 NCBI chr17:64,498,254...64,506,866
Ensembl chr17:64,498,254...64,508,199 		JBrowse link
G FAT1 FAT atypical cadherin 1 disease_progression ISO associated with Neoplasm Metastasis RGD PMID:33328637 RGD:151347447 NCBI chr 4:186,587,794...186,726,696
Ensembl chr 4:186,587,794...186,726,722 		JBrowse link
G FGF10 fibroblast growth factor 10 ISO Pten conditional KO mouse RGD PMID:24582960 RGD:126928134 NCBI chr 5:44,300,247...44,389,420
Ensembl chr 5:44,300,247...44,389,706 		JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase ISS MouseDO NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452 		JBrowse link
G KNSTRN kinetochore localized astrin (SPAG5) binding protein IAGP DNA:mutation:cds: p.Ala40Glu (human)
DNA:mutation:cds: p.Ser24Phe(human)		 RGD PMID:30972880 PMID:25194279 RGD:28867225, RGD:28867226 NCBI chr15:40,382,721...40,394,288
Ensembl chr15:40,382,721...40,394,288 		JBrowse link
G PTEN phosphatase and tensin homolog ameliorates ISO RGD PMID:24582960 RGD:126928134 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
Sporadic Papillary Renal Cell Carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYC MYC proto-oncogene, bHLH transcription factor severity IEP mRNA:increased expression:renal cortex (human)
protein:increased expression:kidney (human)		 RGD PMID:19384955 PMID:17409424 RGD:7240562, RGD:7240563 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM19 ADAM metallopeptidase domain 19 IAGP ClinVar Annotator: match by term: Squamous cell carcinoma ClinVar PMID:27993330 NCBI chr 5:157,477,304...157,575,775
Ensembl chr 5:157,395,534...157,575,775 		JBrowse link
G ADAMTSL3 ADAMTS like 3 IAGP ClinVar Annotator: match by term: Squamous cell carcinoma ClinVar PMID:27993330 NCBI chr15:83,654,123...84,039,842
Ensembl chr15:83,654,088...84,039,842 		JBrowse link
G AFAP1L2 actin filament associated protein 1 like 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29059373 NCBI chr10:114,280,725...114,405,175
Ensembl chr10:114,294,824...114,404,756 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 EXP
IAGP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Squamous cell carcinoma		 CTD
ClinVar		 PMID:21351258 PMID:27993330 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G ANXA1 annexin A1 IEP
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:15274141 PMID:8919037 RGD:7421562 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,629 		JBrowse link
G ANXA2 annexin A2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15274141 NCBI chr15:60,347,151...60,397,986
Ensembl chr15:60,347,134...60,402,883 		JBrowse link
G ANXA5 annexin A5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15274141 NCBI chr 4:121,667,946...121,696,980
Ensembl chr 4:121,667,946...121,696,995 		JBrowse link
G APC APC regulator of WNT signaling pathway IAGP ClinVar Annotator: match by term: Squamous cell carcinoma ClinVar PMID:27993330 NCBI chr 5:112,707,498...112,846,239
Ensembl chr 5:112,707,518...112,846,239 		JBrowse link
G APOBEC3B apolipoprotein B mRNA editing enzyme catalytic subunit 3B EXP CTD Direct Evidence: marker/mechanism CTD PMID:23852168 NCBI chr22:38,982,347...38,992,779
Ensembl chr22:38,982,347...38,992,804 		JBrowse link
G AQP3 aquaporin 3 (Gill blood group) EXP CTD Direct Evidence: marker/mechanism CTD PMID:21401805 NCBI chr 9:33,441,160...33,447,593
Ensembl chr 9:33,441,156...33,447,596 		JBrowse link
G AREG amphiregulin EXP CTD Direct Evidence: therapeutic CTD PMID:11237771 NCBI chr 4:74,445,136...74,455,005
Ensembl chr 4:74,445,136...74,455,005 		JBrowse link
G ATM ATM serine/threonine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:25125259 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102 		JBrowse link
G BCL2 BCL2 apoptosis regulator disease_progression ISO Protein:increased expression:tongue;associated with mouth neoplasms RGD PMID:16309543 RGD:1599477 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26432044 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636 		JBrowse link
G CARD18 caspase recruitment domain family member 18 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22514692 NCBI chr11:105,137,714...105,139,769
Ensembl chr11:105,137,714...105,531,697 		JBrowse link
G CAV1 caveolin 1 ISO RGD PMID:23267770 RGD:8661786 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25199511 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCND1 cyclin D1 susceptibility IAGP
EXP		 associated with Cervix Neoplasms;DNA:polymorphism: :870A>G
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:26432044 PMID:18548202 RGD:2296032 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CD163 CD163 molecule IAGP ClinVar Annotator: match by term: Squamous cell carcinoma ClinVar PMID:27993330 NCBI chr12:7,470,811...7,503,777
Ensembl chr12:7,470,811...7,503,893 		JBrowse link
G CDH1 cadherin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17520682 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A disease_progression IEP associated with Varicose Ulcer;protein:increased expression:skin: RGD PMID:9655223 PMID:11028856 RGD:8662356, RGD:8662856 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A ISO
EXP		 DNA:transitions: :multiple
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:25125259 PMID:15057871 RGD:8552295 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301 		JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B IEP protein:decreased expression:skin RGD PMID:18564286 RGD:8548686 NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305 		JBrowse link
G CEBPA CCAAT enhancer binding protein alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:17510391 PMID:21346772 NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534 		JBrowse link
G CFH complement factor H IEP mRNA:increased expression:skin RGD PMID:23938460 RGD:8662319 NCBI chr 1:196,652,043...196,747,504
Ensembl chr 1:196,651,754...196,752,476 		JBrowse link
G CHRNA3 cholinergic receptor nicotinic alpha 3 subunit IAGP ClinVar Annotator: match by term: Squamous cell carcinoma ClinVar PMID:27993330 NCBI chr15:78,593,052...78,620,996
Ensembl chr15:78,593,052...78,621,295 		JBrowse link
G CHRNA5 cholinergic receptor nicotinic alpha 5 subunit IAGP ClinVar Annotator: match by term: Squamous cell carcinoma ClinVar PMID:27993330 NCBI chr15:78,565,520...78,595,269
Ensembl chr15:78,565,520...78,595,269 		JBrowse link
G CLDN1 claudin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:33665778 NCBI chr 3:190,305,707...190,322,446
Ensembl chr 3:190,305,707...190,322,446 		JBrowse link
G CLU clusterin severity ISO RGD PMID:15126350 RGD:8936706 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700 		JBrowse link
G CREBBP CREB binding protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713 		JBrowse link
G CRYAB crystallin alpha B EXP CTD Direct Evidence: marker/mechanism CTD PMID:15274141 NCBI chr11:111,908,564...111,923,740
Ensembl chr11:111,908,564...111,923,722 		JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18572023 NCBI chr20:472,498...543,790
Ensembl chr20:472,498...543,835 		JBrowse link
G CSNK2A2 casein kinase 2 alpha 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18572023 NCBI chr16:58,157,907...58,198,106
Ensembl chr16:58,157,907...58,198,106 		JBrowse link
G CSNK2B casein kinase 2 beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:18572023 NCBI chr 6:31,666,080...31,670,067
Ensembl chr 6:31,665,227...31,670,343 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 susceptibility IAGP DNA:SNP: :rs3087243(human) RGD PMID:19622768 RGD:7411686 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965 		JBrowse link
G CTTN cortactin EXP CTD Direct Evidence: marker/mechanism CTD PMID:27148699 NCBI chr11:70,398,529...70,436,575
Ensembl chr11:70,398,404...70,436,584 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15956251 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22072123 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22114726 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G DSPP dentin sialophosphoprotein EXP CTD Direct Evidence: marker/mechanism CTD PMID:21103065 NCBI chr 4:87,608,529...87,616,873
Ensembl chr 4:87,608,529...87,616,873 		JBrowse link
G DUSP1 dual specificity phosphatase 1 IEP mRNA:increased expression:saliva RGD PMID:23892499 RGD:7771538 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195 		JBrowse link
G EGFR epidermal growth factor receptor EXP
IAGP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Squamous cell carcinoma		 CTD
ClinVar		 PMID:12942316 PMID:22042947 PMID:22948846 PMID:27993330 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EGR1 early growth response 1 IEP
IAGP		 mRNA:decreased expression:tumor (human)
ClinVar Annotator: match by term: Squamous cell carcinoma		 ClinVar
RGD		 PMID:27993330 PMID:11948124 RGD:5131942 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303 		JBrowse link
G ENO1 enolase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15274141 NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190 		JBrowse link
G EP300 E1A binding protein p300 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,510...41,180,077 		JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:17687452 NCBI chr19:45,349,837...45,370,573
Ensembl chr19:45,349,837...45,370,918 		JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor severity ISO associated with Cockayne Syndrome RGD PMID:9150142 RGD:10401099 NCBI chr10:49,434,881...49,539,538
Ensembl chr10:49,454,168...49,539,538 		JBrowse link
G FAM13A family with sequence similarity 13 member A IAGP ClinVar Annotator: match by term: Squamous cell carcinoma ClinVar PMID:27993330 NCBI chr 4:88,725,960...89,057,185
Ensembl chr 4:88,725,955...89,111,398 		JBrowse link
G FAS Fas cell surface death receptor IAGP ClinVar Annotator: match by term: SQUAMOUS CELL CARCINOMA, BURN SCAR-RELATED, SOMATIC ClinVar PMID:10620127 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FGF7 fibroblast growth factor 7 IEP cervical squamous cell carcinoma; mRNA:increased expression:cervical squamous cells RGD PMID:17306351 RGD:2289084 NCBI chr15:49,423,242...49,488,775
Ensembl chr15:49,423,237...49,488,775 		JBrowse link
G FGFR1 fibroblast growth factor receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22286583 PMID:27794399 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 IEP cervical squamous cell carcinoma; mRNA:increased expression:cervical squamous cells RGD PMID:17306351 RGD:2289084 NCBI chr10:121,478,330...121,598,458
Ensembl chr10:121,478,332...121,598,458 		JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase IAGP cervical squamous cell carcinoma; DNA:hypermethylation,loss of heterozygosity:promoter,locus:hypermethylation in 24%, LOH in 10% of tumors RGD PMID:17467893 RGD:2289871 NCBI chr 3:59,747,277...61,251,452
Ensembl chr 3:59,747,277...61,251,459 		JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 IAGP ClinVar Annotator: match by term: Squamous cell carcinoma ClinVar PMID:27993330 NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145 		JBrowse link
G FOXA1 forkhead box A1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:32717239 NCBI chr14:37,589,552...37,595,249
Ensembl chr14:37,589,552...37,596,059 		JBrowse link
G FOXP2 forkhead box P2 IAGP ClinVar Annotator: match by term: Squamous cell carcinoma ClinVar PMID:27993330 NCBI chr 7:114,086,327...114,693,765
Ensembl chr 7:114,086,327...114,693,772 		JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase EXP CTD Direct Evidence: marker/mechanism CTD PMID:15274141 NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374 		JBrowse link
G GPX1 glutathione peroxidase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15557674 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GREP1 glycine rich extracellular protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34652879 NCBI chr16:2,988,262...3,002,011
Ensembl chr16:2,988,256...3,002,295 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22072123 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 IAGP RGD PMID:11511301 RGD:6906882 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G HCAR2 hydroxycarboxylic acid receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21655214 NCBI chr12:122,701,293...122,703,357
Ensembl chr12:122,701,293...122,703,357 		JBrowse link
G HCAR3 hydroxycarboxylic acid receptor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21655214 NCBI chr12:122,714,756...122,716,811
Ensembl chr12:122,714,756...122,716,811 		JBrowse link
G HDAC1 histone deacetylase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21527555 NCBI chr 1:32,292,083...32,333,626
Ensembl chr 1:32,292,083...32,333,635 		JBrowse link
G HDAC2 histone deacetylase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21527555 NCBI chr 6:113,933,028...113,971,148
Ensembl chr 6:113,933,028...114,011,308 		JBrowse link
G HGF hepatocyte growth factor EXP CTD Direct Evidence: therapeutic CTD PMID:21273587 NCBI chr 7:81,699,010...81,770,047
Ensembl chr 7:81,699,010...81,770,438 		JBrowse link
G HRAS HRas proto-oncogene, GTPase IAGP
EXP		 associated with Xeroderma Pigmentosum;missense mutations:cds:pG12V, pQ61H (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:24224046 PMID:25125259 PMID:8453633 RGD:10412316 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15274141 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15274141 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,305,813 		JBrowse link
G HTR4 5-hydroxytryptamine receptor 4 IAGP ClinVar Annotator: match by term: Squamous cell carcinoma ClinVar PMID:27993330 NCBI chr 5:148,451,032...148,654,527
Ensembl chr 5:148,446,042...148,677,235 		JBrowse link
G IFNA2 interferon alpha 2 EXP CTD Direct Evidence: therapeutic CTD PMID:17172406 NCBI chr 9:21,384,255...21,385,398
Ensembl chr 9:21,384,255...21,385,398 		JBrowse link
G IL2 interleukin 2 treatment IDA RGD PMID:11023201 RGD:8663457 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL6 interleukin 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26372664 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G ING1 inhibitor of growth family member 1 IAGP squamous cell carcinoma of the head and neck, OMIM:275355 DNA:point_mutation:CDS:G->C in exon 2, amino acid cys215ser RGD PMID:10866301 RGD:1600155 NCBI chr13:110,712,623...110,723,339
Ensembl chr13:110,712,736...110,723,339 		JBrowse link
G INPP5A inositol polyphosphate-5-phosphatase A EXP CTD Direct Evidence: marker/mechanism CTD PMID:25759212 NCBI chr10:132,537,787...132,783,480
Ensembl chr10:132,537,787...132,783,480 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 disease_progression IMP RGD PMID:24302991 RGD:7495785 NCBI chr  X:154,010,507...154,019,902
Ensembl chr  X:154,010,506...154,019,902 		JBrowse link
G ITGA5 integrin subunit alpha 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21401805 NCBI chr12:54,395,261...54,419,266
Ensembl chr12:54,395,261...54,419,266 		JBrowse link
G ITGB1 integrin subunit beta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21401805 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792 		JBrowse link
G IVL involucrin EXP CTD Direct Evidence: marker/mechanism CTD PMID:18572023 NCBI chr 1:152,908,546...152,911,886
Ensembl chr 1:152,908,546...152,911,886 		JBrowse link
G KDR kinase insert domain receptor ISO RGD PMID:16251423 RGD:8551848 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595 		JBrowse link
G KITLG KIT ligand ISO Squamous cell carcinoma of the digit OMIA PMID:1399782 PMID:2800263 PMID:6354679 PMID:6731733 PMID:7657570 More... NCBI chr12:88,492,793...88,580,471
Ensembl chr12:88,492,793...88,580,851 		JBrowse link
G KLF5 KLF transcription factor 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr13:73,054,976...73,077,538
Ensembl chr13:73,054,976...73,077,541 		JBrowse link
G KMT2C lysine methyltransferase 2C severity IAGP DNA:mutations:multiple (human) RGD PMID:25303977 RGD:9588232 NCBI chr 7:152,134,925...152,436,003
Ensembl chr 7:152,134,922...152,436,644 		JBrowse link
G KNSTRN kinetochore localized astrin (SPAG5) binding protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:25194279 NCBI chr15:40,382,721...40,394,288
Ensembl chr15:40,382,721...40,394,288 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase EXP CTD Direct Evidence: marker/mechanism CTD PMID:19435901 PMID:25125259 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936 		JBrowse link
G KRT1 keratin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18572023 NCBI chr12:52,674,736...52,680,407
Ensembl chr12:52,674,736...52,680,407 		JBrowse link
G KRT10 keratin 10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18572023 NCBI chr17:40,818,117...40,822,614
Ensembl chr17:40,818,117...40,822,614 		JBrowse link
G KRT14 keratin 14 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16543248 NCBI chr17:41,582,279...41,586,895
Ensembl chr17:41,582,279...41,586,895 		JBrowse link
G KRT6B keratin 6B EXP CTD Direct Evidence: marker/mechanism CTD PMID:15274141 NCBI chr12:52,446,651...52,452,146
Ensembl chr12:52,446,651...52,452,146 		JBrowse link
G LGALS7 galectin 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15274141 NCBI chr19:38,770,968...38,773,517
Ensembl chr19:38,789,200...38,791,754
Ensembl chr19:38,789,200...38,791,754 		JBrowse link
G LGR6 leucine rich repeat containing G protein-coupled receptor 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28945253 NCBI chr 1:202,193,799...202,319,761
Ensembl chr 1:202,193,799...202,319,781 		JBrowse link
G LOC110006318 serine/threonine kinase 11 intron 3 Alu-mediated recombination region IAGP ClinVar Annotator: match by term: Squamous cell carcinoma ClinVar PMID:27993330 NCBI chr19:1,219,531...1,219,844 JBrowse link
G LOC126807524 BRD4-independent group 4 enhancer GRCh37_chr5:137799954-137801153 IAGP ClinVar Annotator: match by term: Squamous cell carcinoma ClinVar PMID:27993330 NCBI chr 5:138,464,083...138,466,217 JBrowse link
G LOC130009460 ATAC-STARR-seq lymphoblastoid silent region 5213 IAGP ClinVar Annotator: match by term: Squamous cell carcinoma ClinVar PMID:27993330 NCBI chr13:28,494,744...28,494,863 JBrowse link
G LORICRIN loricrin cornified envelope precursor protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:18572023 NCBI chr 1:153,259,687...153,262,124
Ensembl chr 1:153,259,687...153,262,124 		JBrowse link
G LTA4H leukotriene A4 hydrolase ISO protein:increased expression:tongue, carcinoma, stroma (rat) RGD PMID:17985342 RGD:2316582 NCBI chr12:96,000,753...96,043,520
Ensembl chr12:96,000,753...96,043,520 		JBrowse link
G LZTS1 leucine zipper tumor suppressor 1 IAGP esophageal squamous cell carcinoma, OMIM:133239 RGD PMID:10097140 RGD:1600104 NCBI chr 8:20,246,165...20,303,963
Ensembl chr 8:20,246,165...20,303,963 		JBrowse link
G MAL mal, T cell differentiation protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:19445022 NCBI chr 2:95,025,708...95,053,992
Ensembl chr 2:95,025,677...95,053,992 		JBrowse link
G MANF mesencephalic astrocyte derived neurotrophic factor susceptibility IAGP RGD PMID:8971156 RGD:1599219 NCBI chr 3:51,385,291...51,389,397
Ensembl chr 3:51,385,291...51,389,397 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21401805 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21401805 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:22948846 NCBI chr 7:116,672,196...116,798,377
Ensembl chr 7:116,672,196...116,798,377 		JBrowse link
G MIR205 microRNA 205 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21563230 NCBI chr 1:209,432,133...209,432,242
Ensembl chr 1:209,432,133...209,432,242 		JBrowse link
G MLH1 mutL homolog 1 IAGP ClinVar Annotator: match by term: Squamous cell carcinoma ClinVar PMID:27993330 NCBI chr 3:36,993,466...37,050,846
Ensembl chr 3:36,993,226...37,050,896 		JBrowse link
G MMP2 matrix metallopeptidase 2 IEP protein:increased expression:nasal mucosa RGD PMID:21624249 RGD:8657057 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP9 matrix metallopeptidase 9 IEP
EXP
ISO		 protein:increased expression:middle ear
CTD Direct Evidence: marker/mechanism
protein:increased expression:nasal mucosa
mRNA:increased expression:tongue		 CTD
RGD		 PMID:18572023 PMID:22178867 PMID:21624249 PMID:18254958 PMID:11081634 RGD:8547836, RGD:8657057, RGD:8547895, RGD:8547854 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MRPL13 mitochondrial ribosomal protein L13 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15274141 NCBI chr 8:120,395,437...120,445,150
Ensembl chr 8:120,380,761...120,445,402 		JBrowse link
G MS4A1 membrane spanning 4-domains A1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22514692 NCBI chr11:60,455,847...60,470,752
Ensembl chr11:60,455,846...60,470,752 		JBrowse link
G MT1A metallothionein 1A EXP CTD Direct Evidence: marker/mechanism CTD PMID:17418620 NCBI chr16:56,638,666...56,640,087
Ensembl chr16:56,638,666...56,640,087 		JBrowse link
G MT1X metallothionein 1X ISO CTD Direct Evidence: marker/mechanism CTD PMID:16543248 NCBI chr16:56,682,470...56,684,196
Ensembl chr16:56,682,470...56,684,196 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase susceptibility IAGP DNA:transition:cds:g.677C>T (human) RGD PMID:17627246 RGD:6893580 NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455 		JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming IAGP ClinVar Annotator: match by term: Squamous cell carcinoma ClinVar PMID:27993330 NCBI chr11:1,157,953...1,201,138
Ensembl chr11:1,157,953...1,201,138 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:26432044 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G NCOA3 nuclear receptor coactivator 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20852035 NCBI chr20:47,501,887...47,656,872
Ensembl chr20:47,501,887...47,656,877 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18572023 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NKX2-1 NK2 homeobox 1 IAGP ClinVar Annotator: match by term: Squamous cell carcinoma ClinVar PMID:27993330 NCBI chr14:36,516,397...36,520,232
Ensembl chr14:36,516,392...36,521,149 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 IAGP ClinVar Annotator: match by term: Squamous cell carcinoma ClinVar PMID:27993330 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,332,331...247,449,108 		JBrowse link
G NME1 NME/NM23 nucleoside diphosphate kinase 1 severity IEP protein:decreased expression:tumor (human) RGD PMID:8978595 RGD:5133245 NCBI chr17:51,153,559...51,162,168
Ensembl chr17:51,153,559...51,162,428 		JBrowse link
G NOTCH1 notch receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27923803 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048 		JBrowse link
G NOTCH2 notch receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27923803 NCBI chr 1:119,911,553...120,069,662
Ensembl chr 1:119,911,553...120,100,779 		JBrowse link
G NOTCH3 notch receptor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27923803 NCBI chr19:15,159,038...15,200,995
Ensembl chr19:15,159,038...15,200,995 		JBrowse link
G NOTCH4 notch receptor 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27923803 NCBI chr 6:32,194,843...32,224,067
Ensembl chr 6:32,194,843...32,224,067 		JBrowse link
G OCA2 OCA2 melanosomal transmembrane protein susceptibility IAGP DNA:missense mutation:cds:p.A481T (rs74653330) (human) RGD PMID:24617981 RGD:9491831 NCBI chr15:27,719,008...28,099,315
Ensembl chr15:27,754,875...28,099,315 		JBrowse link
G OGG1 8-oxoguanine DNA glycosylase ISO RGD PMID:16024598 RGD:8657138 NCBI chr 3:9,749,952...9,783,108
Ensembl chr 3:9,749,944...9,788,219 		JBrowse link
G PGAM1 phosphoglycerate mutase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15274141 NCBI chr10:97,426,191...97,433,444
Ensembl chr10:97,426,191...97,433,444 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:24224046 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093 		JBrowse link
G PLAU plasminogen activator, urokinase severity IEP mRNA:increased expression:oral cavity (human) RGD PMID:12866027 RGD:7241134 NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496 		JBrowse link
G PPIA peptidylprolyl isomerase A EXP CTD Direct Evidence: marker/mechanism CTD PMID:15274141 NCBI chr 7:44,796,681...44,803,117
Ensembl chr 7:44,796,680...44,824,564 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:25125259 NCBI chr 8:47,773,111...47,960,136
Ensembl chr 8:47,773,111...47,960,178 		JBrowse link
G PRTFDC1 phosphoribosyl transferase domain containing 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17599052 NCBI chr10:24,848,614...24,952,606
Ensembl chr10:24,848,614...24,952,606 		JBrowse link
G PTEN phosphatase and tensin homolog IAGP ClinVar Annotator: match by term: Squamous cell carcinoma ClinVar PMID:27993330 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G PTGER1 prostaglandin E receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21739481 NCBI chr19:14,472,466...14,475,354
Ensembl chr19:14,472,466...14,475,354 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16543248 PMID:18202791 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTK2 protein tyrosine kinase 2 EXP CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:21401805 PMID:25199511 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26432044 NCBI chr12:112,418,947...112,509,918
Ensembl chr12:112,418,351...112,509,918 		JBrowse link
G PYCARD PYD and CARD domain containing EXP CTD Direct Evidence: marker/mechanism CTD PMID:16778195 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450 		JBrowse link
G RACK1 receptor for activated C kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15274141 NCBI chr 5:181,236,897...181,243,906
Ensembl chr 5:181,236,897...181,248,096 		JBrowse link
G RAD52 RAD52 homolog, DNA repair protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:26013599 NCBI chr12:911,736...991,122
Ensembl chr12:911,736...990,053 		JBrowse link
G RARB retinoic acid receptor beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:17549354 NCBI chr 3:24,829,321...25,597,932
Ensembl chr 3:24,687,887...25,597,932 		JBrowse link
G RASA1 RAS p21 protein activator 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 5:87,267,883...87,391,916
Ensembl chr 5:87,267,883...87,391,931 		JBrowse link
G RB1 RB transcriptional corepressor 1 IAGP ClinVar Annotator: match by term: Squamous cell carcinoma ClinVar PMID:27993330 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436 		JBrowse link
G RIN3 Ras and Rab interactor 3 IAGP ClinVar Annotator: match by term: Squamous cell carcinoma ClinVar PMID:27993330 NCBI chr14:92,513,781...92,688,994
Ensembl chr14:92,513,781...92,688,994 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 IEP RGD PMID:19778795 RGD:7777170 NCBI chr 6:3,063,967...3,115,187
Ensembl chr 6:3,063,824...3,115,187 		JBrowse link
G RNF168 ring finger protein 168 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34873829 NCBI chr 3:196,468,783...196,503,768
Ensembl chr 3:196,468,783...196,503,768 		JBrowse link
G RNF6 ring finger protein 6 IAGP RGD PMID:12154016 RGD:1599613 NCBI chr13:26,132,115...26,223,085
Ensembl chr13:26,132,115...26,222,314 		JBrowse link
G ROS1 ROS proto-oncogene 1, receptor tyrosine kinase IAGP ClinVar Annotator: match by term: Squamous cell carcinoma ClinVar PMID:27993330 NCBI chr 6:117,287,353...117,425,942
Ensembl chr 6:117,287,353...117,425,942 		JBrowse link
G RPE65 retinoid isomerohydrolase RPE65 IEP mRNA:decreased expression:skin (human) RGD PMID:16181461 RGD:9495923 NCBI chr 1:68,428,822...68,449,954
Ensembl chr 1:68,428,822...68,451,103 		JBrowse link
G SEM1 SEM1 26S proteasome subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:18922899 NCBI chr 7:96,481,626...96,709,846
Ensembl chr 7:96,481,626...96,709,880 		JBrowse link
G SERPINA1 serpin family A member 1 IAGP ClinVar Annotator: match by term: Squamous cell carcinoma ClinVar PMID:27296815 PMID:27993330 PMID:36367950 NCBI chr14:94,376,747...94,390,635
Ensembl chr14:94,376,747...94,390,693 		JBrowse link
G SERPINB3 serpin family B member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15274141 NCBI chr18:63,655,197...63,661,893
Ensembl chr18:63,655,197...63,661,893 		JBrowse link
G SFN stratifin EXP CTD Direct Evidence: marker/mechanism CTD PMID:15274141 NCBI chr 1:26,863,149...26,864,456
Ensembl chr 1:26,863,149...26,864,456 		JBrowse link
G SFTA3 surfactant associated 3 IAGP ClinVar Annotator: match by term: Squamous cell carcinoma ClinVar PMID:27993330 NCBI chr14:36,473,288...36,519,556
Ensembl chr14:36,473,207...36,521,149
Ensembl chr14:36,473,207...36,521,149 		JBrowse link
G SIRT3 sirtuin 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472714 NCBI chr11:215,030...236,931
Ensembl chr11:215,030...236,931 		JBrowse link
G SLC45A2 solute carrier family 45 member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19578363 NCBI chr 5:33,944,623...33,984,693
Ensembl chr 5:33,944,623...33,984,693 		JBrowse link
G SMURF2 SMAD specific E3 ubiquitin protein ligase 2 TAS esophageal RGD PMID:17726579 RGD:2302550 NCBI chr17:64,542,282...64,662,307
Ensembl chr17:64,542,282...64,662,307 		JBrowse link
G SOD2 superoxide dismutase 2 EXP CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:12543247 PMID:15274141 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SOX2 SRY-box transcription factor 2 IEP
EXP		 protein:increased expression:mammalian vulva, epithelium
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:19801978 PMID:23518916 RGD:8661666 NCBI chr 3:181,711,925...181,714,436
Ensembl chr 3:181,711,925...181,714,436 		JBrowse link
G SPRR1A small proline rich protein 1A EXP CTD Direct Evidence: marker/mechanism CTD PMID:8617999 NCBI chr 1:152,984,081...152,985,814
Ensembl chr 1:152,984,081...152,985,814 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 disease_progression IDA
EXP		 protein:increased phosphorylation:skin
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:17566705 PMID:26432044 PMID:16043897 RGD:8694300 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G STK11 serine/threonine kinase 11 EXP
IAGP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Squamous cell carcinoma		 CTD
ClinVar		 PMID:17676035 PMID:27993330 NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431 		JBrowse link
G TERC telomerase RNA component EXP CTD Direct Evidence: therapeutic CTD PMID:16051514 NCBI chr 3:169,764,610...169,765,060
Ensembl chr 3:169,764,610...169,765,047
Ensembl chr 3:169,764,610...169,765,047 		JBrowse link
G TERF1 telomeric repeat binding factor 1 ISO RGD PMID:19679647 RGD:2317221 NCBI chr 8:73,008,864...73,048,123
Ensembl chr 8:73,008,856...73,048,123 		JBrowse link
G TET2 tet methylcytosine dioxygenase 2 IAGP ClinVar Annotator: match by term: Squamous cell carcinoma ClinVar PMID:27993330 NCBI chr 4:105,145,875...105,279,803
Ensembl chr 4:105,145,875...105,279,816 		JBrowse link
G TET2-AS1 TET2 antisense RNA 1 IAGP ClinVar Annotator: match by term: Squamous cell carcinoma ClinVar PMID:27993330 NCBI chr 4:105,171,354...105,352,881
Ensembl chr 4:105,171,354...105,353,011 		JBrowse link
G TGFB1 transforming growth factor beta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20852150 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TIAM1 TIAM Rac1 associated GEF 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27862620 NCBI chr21:31,118,418...31,559,087
Ensembl chr21:31,118,416...31,559,977 		JBrowse link
G TLR4 toll like receptor 4 IAGP ClinVar Annotator: match by term: Squamous cell carcinoma ClinVar PMID:27993330 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR9 toll like receptor 9 IEP invasive squamous cell carcinoma of the cervix; mRNA:increased expression:tumor:significantly increased vs normal cervical tissue (p=0.012) RGD PMID:17440926 RGD:2301099 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A ISO RGD PMID:15044707 RGD:8661739 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TP53 tumor protein p53 ISO
IAGP
EXP
IEP		 ClinVar Annotator: match by term: Squamous cell carcinoma
ClinVar Annotator: match by term: Epidermoid carcinoma
CTD Direct Evidence: marker/mechanism
protein:increased expression:oral mucosa:
DNA:polymorphism,mutations:cds:		 ClinVar
CTD
RGD		 PMID:1672732 PMID:9472631 PMID:9572492 PMID:10557074 PMID:10713666 More... RGD:8547790, RGD:8547855, RGD:8547832, RGD:8547794 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TP63 tumor protein p63 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21527555 NCBI chr 3:189,596,746...189,897,276
Ensembl chr 3:189,631,389...189,897,276 		JBrowse link
G TPI1 triosephosphate isomerase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15274141 NCBI chr12:6,867,420...6,870,948
Ensembl chr12:6,867,119...6,870,948 		JBrowse link
G TSC1 TSC complex subunit 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18538015 NCBI chr 9:132,891,349...132,945,378
Ensembl chr 9:132,891,348...132,946,874 		JBrowse link
G TSC2 TSC complex subunit 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18538015 NCBI chr16:2,047,985...2,089,491
Ensembl chr16:2,047,967...2,089,491 		JBrowse link
G TYMS thymidylate synthetase EXP CTD Direct Evidence: marker/mechanism CTD PMID:16280240 NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578 		JBrowse link
G UBA1 ubiquitin like modifier activating enzyme 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19014429 NCBI chr  X:47,190,847...47,215,128
Ensembl chr  X:47,190,861...47,215,128 		JBrowse link
G UBA7 ubiquitin like modifier activating enzyme 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19014429 NCBI chr 3:49,805,209...49,813,953
Ensembl chr 3:49,805,209...49,813,953 		JBrowse link
G UMPS uridine monophosphate synthetase EXP CTD Direct Evidence: marker/mechanism CTD PMID:16757204 NCBI chr 3:124,730,452...124,749,273
Ensembl chr 3:124,730,433...124,749,273 		JBrowse link
G VDAC2 voltage dependent anion channel 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15274141 NCBI chr10:75,210,170...75,231,448
Ensembl chr10:75,210,154...75,231,448 		JBrowse link
G VDR vitamin D receptor IAGP DNA:SNPs, haplotype: :rs731236, rs7975232 (human)
DNA:SNP: :rs1544410 (human)		 RGD PMID:22213323 PMID:16950800 RGD:8158063, RGD:8158080 NCBI chr12:47,841,537...47,904,994
Ensembl chr12:47,841,537...47,943,048 		JBrowse link
G VEGFA vascular endothelial growth factor A EXP CTD Direct Evidence: marker/mechanism CTD PMID:15956251 PMID:26432044 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G WWOX WW domain containing oxidoreductase IAGP
EXP		 esophageal squamous cell carcinoma, OMIM:133239
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:17575124 PMID:11956080 RGD:1599874 NCBI chr16:78,099,654...79,212,667
Ensembl chr16:78,099,400...79,212,667 		JBrowse link
G XPC XPC complex subunit, DNA damage recognition and repair factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:27777383 NCBI chr 3:14,145,147...14,178,601
Ensembl chr 3:14,145,145...14,178,621 		JBrowse link
G XRCC5 X-ray repair cross complementing 5 IEP protein:increased expression:epidermal cell, squamous cell of epidermis (human) RGD PMID:16497868 RGD:8698657 NCBI chr 2:216,109,348...216,206,293
Ensembl chr 2:216,107,464...216,206,303 		JBrowse link
G XRCC6 X-ray repair cross complementing 6 IEP protein:increased expression:epidermal cell, squamous cell of epidermis (human) RGD PMID:16497868 RGD:8698657 NCBI chr22:41,621,295...41,664,041
Ensembl chr22:41,621,163...41,664,048 		JBrowse link
tongue squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase IEP protein:increased activity:saliva: RGD PMID:20379753 RGD:152995262 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing disease_progression IEP protein:decreased expression:serum RGD PMID:23181352 RGD:8694469 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G BCL2 BCL2 apoptosis regulator IEP protein:increased expression:tongue (human) RGD PMID:26581505 RGD:11535375 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 exacerbates IEP protein:increased expression:tongue (human) RGD PMID:18621506 RGD:153323319 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670 		JBrowse link
G BRINP3 BMP/retinoic acid inducible neural specific 3 IEP mRNA:decreased expression:tongue: RGD PMID:19787213 RGD:14398487 NCBI chr 1:190,097,658...190,477,864
Ensembl chr 1:190,097,658...190,478,404 		JBrowse link
G CAV2 caveolin 2 IEP protein:increased expression:mucosa of tongue RGD PMID:20558341 RGD:8661771 NCBI chr 7:116,499,738...116,508,541
Ensembl chr 7:116,287,380...116,508,541 		JBrowse link
G CCND1 cyclin D1 IEP protein:increased expression:tongue (human) RGD PMID:26581505 RGD:11535375 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A disease_progression IEP RGD PMID:12162767 RGD:8662376 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 HEP mRNA:increased expression:head, neck (human) RGD PMID:31452775 RGD:150520018 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G EGFR epidermal growth factor receptor treatment ISO RGD PMID:19380367 RGD:8551769 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 disease_progression IEP RGD PMID:19691460 RGD:126781771 NCBI chr12:56,080,108...56,103,505
Ensembl chr12:56,076,799...56,103,505 		JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 severity IEP RGD PMID:19691460 RGD:126781771 NCBI chr 2:211,375,717...212,538,802
Ensembl chr 2:211,375,717...212,538,841 		JBrowse link
G FANCB FA complementation group B IEP RGD PMID:17409780 RGD:11049143 NCBI chr  X:14,689,524...14,873,069
Ensembl chr  X:14,690,388...14,873,255 		JBrowse link
G FANCC FA complementation group C IEP RGD PMID:17409780 RGD:11049143 NCBI chr 9:95,099,054...95,317,709
Ensembl chr 9:95,099,054...95,426,796 		JBrowse link
G FANCF FA complementation group F IEP mRNA:decreased expression:tongue: RGD PMID:17409780 RGD:11049143 NCBI chr11:22,622,533...22,625,823
Ensembl chr11:22,622,533...22,625,823 		JBrowse link
G FANCG FA complementation group G IEP RGD PMID:17409780 RGD:11049143 NCBI chr 9:35,073,839...35,079,942
Ensembl chr 9:35,073,835...35,080,004 		JBrowse link
G FANCI FA complementation group I IEP RGD PMID:17409780 RGD:11049143 NCBI chr15:89,243,979...89,317,259
Ensembl chr15:89,243,945...89,317,261 		JBrowse link
G FANCL FA complementation group L IEP RGD PMID:17409780 RGD:11049143 NCBI chr 2:58,159,243...58,241,380
Ensembl chr 2:58,159,243...58,241,410 		JBrowse link
G FANCM FA complementation group M IEP RGD PMID:17409780 RGD:11049143 NCBI chr14:45,135,930...45,200,890
Ensembl chr14:45,135,930...45,200,890 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit IEP mRNA,protein:increased expression:tongue (human) RGD PMID:26581505 RGD:11535375 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190 		JBrowse link
G FOSB FosB proto-oncogene, AP-1 transcription factor subunit IEP protein:increased expression:tongue (human) RGD PMID:26581505 RGD:11535375 NCBI chr19:45,467,996...45,475,179
Ensembl chr19:45,467,995...45,475,179 		JBrowse link
G FOSL1 FOS like 1, AP-1 transcription factor subunit IEP protein:decreased expression:tongue (human) RGD PMID:26581505 RGD:11535375 NCBI chr11:65,892,049...65,900,545
Ensembl chr11:65,892,049...65,900,573 		JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit IEP mRNA,protein:increased expression:tongue (human) RGD PMID:26581505 RGD:11535375 NCBI chr 2:28,392,858...28,417,317
Ensembl chr 2:28,392,448...28,417,317 		JBrowse link
G FUBP1 far upstream element binding protein 1 exacerbates IEP mRNA, protein:increased expression:tongue (human) RGD PMID:32339054 RGD:151361191 NCBI chr 1:77,944,055...77,979,501
Ensembl chr 1:77,944,055...77,979,110 		JBrowse link
G GJA1 gap junction protein alpha 1 ISO protein:decreased expression:epithelium RGD PMID:23568744 RGD:8662380 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727 		JBrowse link
G HGF hepatocyte growth factor IEP protein:increased expression:tongue: RGD PMID:20848408 RGD:8548612 NCBI chr 7:81,699,010...81,770,047
Ensembl chr 7:81,699,010...81,770,438 		JBrowse link
G IFNG interferon gamma disease_progression ISO protein:decreased expression:serum: RGD PMID:17338814 RGD:8662972 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL10 interleukin 10 disease_progression ISO protein:increased expression:serum: RGD PMID:17338814 RGD:8662972 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL1RL1 interleukin 1 receptor like 1 disease_progression IEP RGD PMID:25193287 RGD:39938972 NCBI chr 2:102,311,563...102,352,356
Ensembl chr 2:102,311,502...102,352,037 		JBrowse link
G IL2 interleukin 2 ISO protein:decreased expression:serum: RGD PMID:17338814 RGD:8662972 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL33 interleukin 33 disease_progression IEP RGD PMID:25193287 RGD:39938972 NCBI chr 9:6,215,149...6,257,983
Ensembl chr 9:6,215,786...6,257,983 		JBrowse link
G JAK3 Janus kinase 3 disease_progression ISO RGD PMID:26860129 RGD:11531126 NCBI chr19:17,824,782...17,847,982
Ensembl chr19:17,824,780...17,848,071 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit IEP mRNA,protein:increased expression:tongue (human) RGD PMID:26581505 RGD:11535375 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit IEP protein:increased expression:tongue (human) RGD PMID:26581505 RGD:11535375 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315 		JBrowse link
G JUND JunD proto-oncogene, AP-1 transcription factor subunit IEP protein:increased expression:tongue (human) RGD PMID:26581505 RGD:11535375 NCBI chr19:18,279,694...18,281,622
Ensembl chr19:18,279,694...18,281,622 		JBrowse link
G KDR kinase insert domain receptor treatment ISO RGD PMID:19380367 RGD:8551769 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595 		JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 IEP mRNA:increased expression:tongue squamous epithelium (human) RGD PMID:28319306 RGD:150429750 NCBI chr17:12,020,877...12,143,828
Ensembl chr17:12,020,829...12,143,830 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase IEP protein:increased expression:tongue: RGD PMID:20848408 RGD:8548612 NCBI chr 7:116,672,196...116,798,377
Ensembl chr 7:116,672,196...116,798,377 		JBrowse link
G MMP9 matrix metallopeptidase 9 IEP protein:increased expression:tongue (human) RGD PMID:26581505 RGD:11535375 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MTUS1 microtubule associated scaffold protein 1 disease_progression IEP RGD PMID:22153618 RGD:25330347 NCBI chr 8:17,643,802...17,801,521
Ensembl chr 8:17,643,795...17,801,094 		JBrowse link
G SLC1A5 solute carrier family 1 member 5 disease_progression IEP RGD PMID:24762957 RGD:151361157 NCBI chr19:46,774,883...46,788,594
Ensembl chr19:46,774,883...46,788,594 		JBrowse link
G SLC3A2 solute carrier family 3 member 2 disease_progression IEP RGD PMID:24762957 RGD:151361157 NCBI chr11:62,856,109...62,888,860
Ensembl chr11:62,856,004...62,888,880 		JBrowse link
G SLC7A11 solute carrier family 7 member 11 severity IEP RGD PMID:24762957 RGD:151361157 NCBI chr 4:138,164,097...138,312,671
Ensembl chr 4:138,164,097...138,242,349 		JBrowse link
G SLC7A5 solute carrier family 7 member 5 disease_progression IEP RGD PMID:24762957 RGD:151361157 NCBI chr16:87,830,023...87,869,507
Ensembl chr16:87,830,016...87,869,507 		JBrowse link
G SOX2 SRY-box transcription factor 2 disease_progression IEP RGD PMID:21689966 RGD:8661665 NCBI chr 3:181,711,925...181,714,436
Ensembl chr 3:181,711,925...181,714,436 		JBrowse link
G TP53 tumor protein p53 ISO protein:increased expression:tongue: RGD PMID:20385474 RGD:8547851 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
tonsil squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGFR3 fibroblast growth factor receptor 3 severity IEP associated with human papillomavirus;protein:decreased expression:tumor cells (human) RGD PMID:30061236 RGD:36947883 NCBI chr 4:1,793,293...1,808,867
Ensembl chr 4:1,793,293...1,808,872 		JBrowse link
vulva squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC25A cell division cycle 25A IEP protein:increased expression:vulva RGD PMID:20500813 RGD:2729590 NCBI chr 3:48,157,146...48,188,417
Ensembl chr 3:48,157,146...48,188,417 		JBrowse link
G CDC25B cell division cycle 25B disease_progression IEP protein:increased expression:vulva RGD PMID:20500813 RGD:2729590 NCBI chr20:3,786,951...3,806,115
Ensembl chr20:3,786,772...3,806,121 		JBrowse link
G CDC25C cell division cycle 25C disease_progression IEP protein:increased expression:vulva RGD PMID:20500813 RGD:2729590 NCBI chr 5:138,285,265...138,338,355
Ensembl chr 5:138,285,269...138,338,355 		JBrowse link
G SFN stratifin IDA DNA, mRNA:hypermethylation, decreased expression:vulva RGD PMID:11896620 RGD:2299936 NCBI chr 1:26,863,149...26,864,456
Ensembl chr 1:26,863,149...26,864,456 		JBrowse link
WHIM syndrome 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXCR4 C-X-C motif chemokine receptor 4 IAGP
ISS
EXP		 DNA:frame shift, nonsense mutations:cds:1016_1017delCT,p.R334X,E343X(human)
ClinVar Annotator: match by term: WHIM syndrome 1
ClinVar Annotator: match by term: CXCR4-related condition | ClinVar Annotator: match by term: WHIM syndrome 1
OMIM:193670
CTD Direct Evidence: marker/mechanism		 ClinVar
MouseDO
CTD
OMIM
RGD		 PMID:12692554 PMID:15026312 PMID:15536153 PMID:16275383 PMID:16899028 More... RGD:734860 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 146647
    disease of cellular proliferation 26499
      benign neoplasm 4006
        cell type benign neoplasm 3264
          squamous cell neoplasm 1273
            acanthoma + 44
            papillary carcinoma + 16
            papilloma + 77
            squamous cell carcinoma + 1180
            verrucous carcinoma + 0
paths to the root