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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:substance-related disorder
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Accession:DOID:303 term browser browse the term
Definition:A disease of mental health involving the abuse or dependence on a substance that is ingested in order to produce a high, alter one's senses, or otherwise affect functioning. (DO)
Synonyms:exact_synonym: PSAB;   organic mental disorders, substance induced;   substance addiction;   substance use disorder;   substance use disorders;   substance-related disorders
 broad_synonym: psychiatric toxicity
 related_synonym: dopamine receptor d2, reduced brain density of;   polysubstance abuse, susceptibility to
 xref: EFO:0011059;   MESH:D019966;   MIM:606581;   MONDO:0002494;   NCI:C92203
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
substance-related disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr15:101,948,387...102,182,912
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Ablim1 actin-binding LIM protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:266,088,868...266,377,169
Ensembl chr 1:256,084,297...256,371,969 		JBrowse link
G Adarb2 adenosine deaminase RNA specific B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr17:66,660,586...67,211,104
Ensembl chr17:61,756,067...62,300,831 		JBrowse link
G Aff3 ALF transcription elongation factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 9:47,894,903...48,352,380
Ensembl chr 9:40,404,375...40,857,247 		JBrowse link
G Agbl4 AGBL carboxypeptidase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 5:130,483,551...131,762,906
Ensembl chr 5:125,254,956...126,534,367 		JBrowse link
G Akap7 A-kinase anchoring protein 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:21,906,503...22,168,663
Ensembl chr 1:20,087,373...20,217,797 		JBrowse link
G Ano4 anoctamin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 7:25,216,389...25,625,811
Ensembl chr 7:23,329,070...23,738,434 		JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 7:22,019,480...22,072,386
Ensembl chr 7:20,135,375...20,184,754 		JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr13:79,319,708...79,340,226
Ensembl chr13:76,786,578...76,807,459 		JBrowse link
G Bcar3 BCAR3 adaptor protein, NSP family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 2:213,209,907...213,323,305
Ensembl chr 2:210,525,260...210,638,798 		JBrowse link
G Bpifa2 BPI fold containing family A, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 3:162,953,538...162,961,497
Ensembl chr 3:142,493,379...142,501,337 		JBrowse link
G C18h5orf63 similar to human chromosome 5 open reading frame 63 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr18:50,424,079...50,442,172
Ensembl chr18:50,424,079...50,441,973 		JBrowse link
G C1h19orf18 similar to human chromosome 19 open reading frame 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:82,094,513...82,122,109
Ensembl chr 1:73,025,988...73,049,736 		JBrowse link
G Cadps2 calcium dependent secretion activator 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 4:52,746,054...53,275,252
Ensembl chr 4:51,781,053...52,309,829 		JBrowse link
G Ccdc91 coiled-coil domain containing 91 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 4:182,132,931...182,304,948
Ensembl chr 4:180,402,376...180,574,364 		JBrowse link
G Cd274 CD274 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:236,526,215...236,549,956
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Cdcp1 CUB domain containing protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 8:131,706,140...131,742,799
Ensembl chr 8:122,828,685...122,865,388 		JBrowse link
G Cdh13 cadherin 13 ISO
IMP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20098672 PMID:28387990 RGD:13503340 NCBI chr19:63,258,251...64,296,122
Ensembl chr19:46,349,430...47,387,459 		JBrowse link
G Cdh13em1Mcwi cadherin 13; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP knock-out compared to wild-type rats RGD PMID:28387990 RGD:13503340
G Cers6 ceramide synthase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 3:74,038,520...74,287,544
Ensembl chr 3:53,630,959...53,876,848 		JBrowse link
G Cftr CF transmembrane conductance regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Chchd3 coiled-coil-helix-coiled-coil-helix domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 4:62,327,574...62,584,085
Ensembl chr 4:61,360,353...61,616,847 		JBrowse link
G Chd1l chromodomain helicase DNA binding protein 1-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 2:187,819,869...187,906,359
Ensembl chr 2:185,139,308...185,217,595 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20393457 NCBI chr 4:65,981,136...66,116,128
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:20438829 NCBI chr 8:64,265,879...64,294,233
Ensembl chr 8:55,369,794...55,398,146 		JBrowse link
G Cnr1 cannabinoid receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9888857 PMID:18690112 PMID:21513772 NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Colec12 collectin sub-family member 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr18:1,005,787...1,193,455
Ensembl chr18:732,950...920,618 		JBrowse link
G Csmd1 CUB and Sushi multiple domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr16:78,920,549...80,520,710
Ensembl chr16:72,218,503...73,817,614 		JBrowse link
G Csmd3 CUB and Sushi multiple domains 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 7:80,637,341...81,956,469
Ensembl chr 7:78,748,480...80,066,369 		JBrowse link
G Csrnp3 cysteine and serine rich nuclear protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 3:70,906,587...71,102,596
Ensembl chr 3:50,498,633...50,685,950 		JBrowse link
G Csrp3 cysteine and glycine rich protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:107,664,338...107,682,916
Ensembl chr 1:98,528,068...98,546,653 		JBrowse link
G Ctnna3 catenin alpha 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr20:23,613,016...25,198,699
Ensembl chr20:23,623,560...25,199,978 		JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr17:8,323,150...8,331,176
Ensembl chr17:8,317,933...8,324,839 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17089107 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Ddx1 DEAD-box helicase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 6:41,725,365...41,756,236
Ensembl chr 6:35,996,469...36,027,365 		JBrowse link
G Disc1 DISC1 scaffold protein severity ISO protein:altered expression:orbitofrontal cortex RGD PMID:15657124 RGD:5509834 NCBI chr19:69,911,548...70,120,970
Ensembl chr19:53,014,616...53,219,778 		JBrowse link
G Dnah8 dynein, axonemal, heavy chain 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr20:8,694,371...8,948,849
Ensembl chr20:8,692,963...8,946,772 		JBrowse link
G Dock1 dedicator of cyto-kinesis 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:198,897,021...199,413,636
Ensembl chr 1:189,467,143...189,983,768 		JBrowse link
G Drd2 dopamine receptor D2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16901644 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Dscam DS cell adhesion molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr11:49,391,385...49,976,861
Ensembl chr11:35,926,896...36,507,415 		JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr11:92,746,409...92,779,647
Ensembl chr11:79,241,938...79,275,188 		JBrowse link
G Eipr1 EARP complex and GARP complex interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 6:51,116,827...51,230,453
Ensembl chr 6:45,388,376...45,502,083 		JBrowse link
G Etv6 ETS variant transcription factor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 4:168,580,405...168,819,817
Ensembl chr 4:166,847,686...167,084,992 		JBrowse link
G Faah fatty acid amide hydrolase susceptibility ISO ClinVar Annotator: match by term: Polysubstance abuse, susceptibility to
CTD Direct Evidence: marker/mechanism
DNA:missense mutation:cds:p.P129T (human)		 ClinVar
OMIM
CTD
RGD		 PMID:12060782 PMID:15254019 PMID:16972078 PMID:19103437 PMID:23556448 More... RGD:1625741, RGD:1300311 NCBI chr 5:134,716,545...134,735,396
Ensembl chr 5:129,479,824...129,498,677 		JBrowse link
G Fam184a family with sequence similarity 184, member A ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr20:33,477,089...33,599,296
Ensembl chr20:32,934,636...33,056,652 		JBrowse link
G Fam184b family with sequence similarity 184, member B ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr14:69,688,031...69,803,922
Ensembl chr14:65,475,489...65,591,388 		JBrowse link
G Farp1 FERM, ARH/RhoGEF and pleckstrin domain protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr15:104,531,196...104,770,148
Ensembl chr15:98,182,329...98,363,299 		JBrowse link
G Faslg Fas ligand IDA RGD PMID:15644446 RGD:1358616 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr15:16,365,401...17,872,901
Ensembl chr15:13,934,995...15,442,340 		JBrowse link
G Fhod3 formin homology 2 domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr18:16,267,830...16,700,508
Ensembl chr18:15,993,324...16,425,796 		JBrowse link
G Fkbp15 FKBP prolyl isomerase family member 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 5:80,766,356...80,830,622
Ensembl chr 5:75,750,787...75,814,990 		JBrowse link
G Frmd4a FERM domain containing 4A ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr17:78,577,062...79,167,924
Ensembl chr17:73,667,789...74,258,687 		JBrowse link
G Gba3 glucosylceramidase beta 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr14:64,787,601...64,934,043
Ensembl chr14:60,574,976...60,721,653 		JBrowse link
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 8:9,845,421...10,320,021
Ensembl chr 8:1,562,119...2,034,979 		JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr20:53,717,564...54,415,283
Ensembl chr20:52,133,851...52,838,375 		JBrowse link
G Grm5 glutamate metabotropic receptor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:150,722,711...151,297,585
Ensembl chr 1:141,312,368...141,882,274 		JBrowse link
G Grm7 glutamate metabotropic receptor 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 4:145,286,714...146,169,099
Ensembl chr 4:143,731,259...144,612,344 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment IMP RGD PMID:30188517 RGD:13792724 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hspa12a heat shock protein family A (Hsp70) member 12A ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:267,921,780...268,083,171
Ensembl chr 1:257,935,644...258,096,846 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C IMP RGD PMID:16474401 RGD:2292548 NCBI chr  X:115,453,190...115,682,325
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Hycc1 hyccin PI4KA lipid kinase complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 4:12,024,692...12,131,504
Ensembl chr 4:11,132,385...11,239,113 		JBrowse link
G Insr insulin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr12:5,991,135...6,129,275
Ensembl chr12:1,197,100...1,330,883 		JBrowse link
G Klf12 KLF transcription factor 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr15:83,037,548...83,469,998
Ensembl chr15:76,637,654...77,062,056 		JBrowse link
G Ldlrad3 low density lipoprotein receptor class A domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 3:108,694,528...108,936,330
Ensembl chr 3:88,239,622...88,481,267 		JBrowse link
G Limch1 LIM and calponin homology domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr14:41,466,433...41,779,477
Ensembl chr14:41,114,803...41,425,191 		JBrowse link
G Lrmda leucine rich melanocyte differentiation associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr15:1,275,139...2,334,153
Ensembl chr15:1,225,710...2,284,749 		JBrowse link
G Macrod2 mono-ADP ribosylhydrolase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 3:148,173,821...150,191,077
Ensembl chr 3:127,720,181...129,734,492 		JBrowse link
G Mknk1 MAPK interacting serine/threonine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 5:134,554,881...134,594,392
Ensembl chr 5:129,318,170...129,357,639 		JBrowse link
G Mpc1 mitochondrial pyruvate carrier 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:54,985,305...54,996,979
Ensembl chr 1:52,437,741...52,449,400 		JBrowse link
G Mpp7 MAGUK p55 scaffold protein 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr17:60,135,096...60,401,814
Ensembl chr17:55,442,696...55,706,748 		JBrowse link
G Msra methionine sulfoxide reductase A ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr15:42,514,818...42,853,278
Ensembl chr15:38,351,445...38,676,585 		JBrowse link
G Myo5c myosin VC ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 8:84,870,031...84,946,996
Ensembl chr 8:75,989,528...76,066,483 		JBrowse link
G Myo6 myosin VI ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 8:89,967,351...90,122,219
Ensembl chr 8:81,087,139...81,239,292 		JBrowse link
G Nme7 NME/NM23 family member 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr13:79,190,462...79,319,890
Ensembl chr13:76,657,367...76,786,765 		JBrowse link
G Npy neuropeptide Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:19063928 NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
G Nrcam neuronal cell adhesion molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123759 NCBI chr 6:67,129,723...67,425,510
Ensembl chr 6:61,329,863...61,702,992 		JBrowse link
G Nrxn3 neurexin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 6:113,372,667...115,004,073
Ensembl chr 6:107,641,780...109,272,044 		JBrowse link
G Oprd1 opioid receptor, delta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17622222 PMID:20098672 NCBI chr 5:149,590,244...149,624,999
Ensembl chr 5:144,306,188...144,340,960 		JBrowse link
G Oprm1 opioid receptor, mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27192616 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Or51e1 olfactory receptor family 51 subfamily E member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:166,554,112...166,564,147
Ensembl chr 1:157,142,352...157,149,671 		JBrowse link
G Pacs1 phosphofurin acidic cluster sorting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:211,866,872...211,998,828
Ensembl chr 1:202,437,505...202,569,473 		JBrowse link
G Parva parvin, alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:175,981,725...176,139,523
Ensembl chr 1:166,547,132...166,704,950 		JBrowse link
G Patj PATJ, crumbs cell polarity complex component ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 5:118,177,557...118,480,301
Ensembl chr 5:113,062,118...113,364,807 		JBrowse link
G Pbx1 PBX homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr13:82,811,664...83,121,447
Ensembl chr13:80,278,770...80,588,594 		JBrowse link
G Pcdh15 protocadherin related 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr20:13,996,383...15,495,206
Ensembl chr20:13,963,565...15,494,719 		JBrowse link
G Pde1c phosphodiesterase 1C ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 4:86,629,074...87,108,147
Ensembl chr 4:85,300,858...85,863,219 		JBrowse link
G Piwil1 piwi-like RNA-mediated gene silencing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr12:33,585,747...33,606,715
Ensembl chr12:27,949,744...27,970,580 		JBrowse link
G Pla2r1 phospholipase A2 receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 3:65,292,629...65,422,462
Ensembl chr 3:44,883,943...45,013,660 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr18:62,255,970...62,262,384
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Polr1d RNA polymerase I and III subunit D ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr12:13,084,505...13,118,069
Ensembl chr12:7,970,595...8,005,624 		JBrowse link
G Prkce protein kinase C, epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 6:13,718,050...14,204,931
Ensembl chr 6:7,965,048...8,451,719 		JBrowse link
G Prkch protein kinase C, eta ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 6:98,027,830...98,226,486
Ensembl chr 6:92,292,000...92,490,654 		JBrowse link
G Prpf4 pre-mRNA splicing tri-snRNP complex factor PRPF4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 5:80,875,511...80,889,501
Ensembl chr 5:75,859,924...75,873,919 		JBrowse link
G Pten phosphatase and tensin homolog IMP RGD PMID:16474401 RGD:2292548 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Qsox1 quiescin sulfhydryl oxidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr13:70,500,060...70,537,711
Ensembl chr13:67,949,780...67,987,459 		JBrowse link
G Rad51b RAD51 paralog B ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 6:103,829,390...104,373,923
Ensembl chr 6:98,098,868...98,640,979 		JBrowse link
G Rhbdd3 rhomboid domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr14:84,208,155...84,214,334
Ensembl chr14:79,994,158...80,000,175 		JBrowse link
G Rtl6 retrotransposon Gag like 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 7:115,684,812...115,689,897
Ensembl chr 7:115,684,739...115,690,052 		JBrowse link
G Samd4a sterile alpha motif domain containing 4A ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr15:22,616,200...22,831,872
Ensembl chr15:20,134,377...20,348,380 		JBrowse link
G Sema6d semaphorin 6D ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 3:131,801,680...132,394,578
Ensembl chr 3:111,883,872...111,941,094 		JBrowse link
G Slc10a2 solute carrier family 10 member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr16:91,088,089...91,111,025
Ensembl chr16:84,374,862...84,409,475 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 IEP protein:increased cysteine nitrosylation:striatum, vesicle (rat) RGD PMID:17683483 RGD:5131179 NCBI chr 1:268,399,815...268,435,229
Ensembl chr 1:258,413,959...258,448,325 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17010131 NCBI chr 1:50,783,218...50,872,358
Ensembl chr 1:48,235,476...48,324,612 		JBrowse link
G Slc2a13 solute carrier family 2 member 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 7:124,278,881...124,606,146
Ensembl chr 7:122,399,330...122,726,605 		JBrowse link
G Slc45a2 solute carrier family 45, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 2:61,690,828...61,723,437
Ensembl chr 2:59,963,706...59,996,317 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19272758 NCBI chr10:62,322,688...62,357,060
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Slk STE20-like kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:256,415,013...256,470,942
Ensembl chr 1:246,473,712...246,526,530 		JBrowse link
G Spmip5 sperm microtubule inner protein 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:267,912,696...267,919,413
Ensembl chr 1:257,926,388...257,934,399 		JBrowse link
G Syne1 spectrin repeat containing nuclear envelope protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:43,917,640...44,388,802
Ensembl chr 1:41,512,030...41,983,322 		JBrowse link
G Tenm2 teneurin transmembrane protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr10:20,984,710...22,121,001
Ensembl chr10:20,481,854...21,705,597 		JBrowse link
G Thsd4 thrombospondin type 1 domain containing 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 8:69,280,397...69,880,144
Ensembl chr 8:60,386,875...61,024,995 		JBrowse link
G Tiam2 TIAM Rac1 associated GEF 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:46,323,450...46,524,769
Ensembl chr 1:43,918,174...44,119,493 		JBrowse link
G Tmprss7 transmembrane serine protease 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr11:68,583,710...68,629,200
Ensembl chr11:55,128,998...55,164,882 		JBrowse link
G Ttc21b tetratricopeptide repeat domain 21B ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 3:71,269,425...71,343,936
Ensembl chr 3:50,861,367...50,935,903 		JBrowse link
G Wdr11 WD repeat domain 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:193,595,606...193,641,149
Ensembl chr 1:184,165,571...184,210,846 		JBrowse link
G Xkr4 XK related 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 5:20,694,433...21,095,350
Ensembl chr 5:15,895,863...16,282,962 		JBrowse link
G Xpo6 exportin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:190,102,719...190,192,138
Ensembl chr 1:180,672,119...180,761,543 		JBrowse link
G Xylt1 xylosyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:181,078,222...181,361,047
Ensembl chr 1:171,643,925...171,926,783 		JBrowse link
G Zfp366 zinc finger protein 366 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 2:32,312,712...32,376,996
Ensembl chr 2:30,578,715...30,642,182 		JBrowse link
G Zfp385d zinc finger protein 385D ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr15:7,473,431...7,854,364
Ensembl chr15:5,042,572...5,423,367 		JBrowse link
G Zfp606 zinc finger protein 606 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:72,981,920...73,022,423
Ensembl chr 1:72,981,989...73,008,072 		JBrowse link
G Zfp804a zinc finger protein 804A ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 3:87,440,496...87,670,872
Ensembl chr 3:67,034,170...67,263,607 		JBrowse link
Acute Alcohol Sensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member ISO ClinVar Annotator: match by term: ALDH2-related condition | ClinVar Annotator: match by term: Alcohol sensitivity, acute | ClinVar Annotator: match by term: Susceptibility to hangover ClinVar PMID:2987944 PMID:4065146 PMID:6650498 PMID:7180842 PMID:7593603 More... NCBI chr12:40,610,244...40,643,220
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
alcohol dependence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcyap1 adenylate cyclase activating polypeptide 1 susceptibility ISO DNA:SNP:: (rs2856966) (human) RGD PMID:20554694 RGD:401976551 NCBI chr 9:120,550,236...120,569,096
Ensembl chr 9:113,103,718...113,109,773 		JBrowse link
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide ISO associated with other drug dependencies; DNA:SNPs:CDS: (rs904096)
ClinVar Annotator: match by term: Alcohol dependence		 OMIM
ClinVar
RGD		 PMID:3397059 PMID:3758060 PMID:10090900 PMID:15863807 PMID:17718394 More... RGD:405650603 NCBI chr 2:229,470,703...229,482,291
Ensembl chr 2:226,797,303...226,808,892 		JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide ISO RGD PMID:20077761 RGD:401827938 NCBI chr 2:229,622,092...229,640,120
Ensembl chr 2:226,947,466...226,987,591 		JBrowse link
G Adra2a adrenoceptor alpha 2A susceptibility ISO
IEP		 DNA:SNP:promoter: C-1291G (rs1800544) (human)
associated with stress-related disorder; mRNA:decreased expression:hypothalamus (rat)		 RGD PMID:21070505 PMID:26121187 RGD:401976462, RGD:401976544 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Ago1 argonaute RISC component 1 susceptibility ISO DNA:SNP:intron:A>G(rs595961)(human) RGD PMID:25495208 RGD:401900681 NCBI chr 5:144,006,618...144,064,740
Ensembl chr 5:138,722,111...138,773,546 		JBrowse link
G Ago2 argonaute RISC catalytic component 2 susceptibility ISO DNA:SNP:promoter:A>C(rs4961280)(human) RGD PMID:25495208 RGD:401900681 NCBI chr 7:106,907,209...106,994,124
Ensembl chr 7:105,029,120...105,104,974 		JBrowse link
G Ahr aryl hydrocarbon receptor ISO mRNA:decreased expression:duodenum: RGD PMID:34454169 RGD:405866377 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 ISO DNA:SNP:cds:rs12529 (p.H5Q)(human) RGD PMID:21323680 RGD:597621634 NCBI chr17:71,020,884...71,037,779
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO ClinVar Annotator: match by term: Alcohol dependence
DNA:SNP: :1510G>A (human)		 ClinVar
RGD		 PMID:2987944 PMID:4065146 PMID:6650498 PMID:7180842 PMID:7593603 More... RGD:401827938, RGD:401827936 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Alk ALK receptor tyrosine kinase ISO DNA:SNP:CDS: (rs7592571) RGD PMID:21703634 RGD:597830064 NCBI chr 6:28,631,431...29,351,321
Ensembl chr 6:22,880,625...23,598,034 		JBrowse link
G Angpt1 angiopoietin 1 ISO associated with other drug dependencies; DNA:SNPs:CDS:intron (rs10090742) RGD PMID:27151647 RGD:405650603 NCBI chr 7:75,415,959...75,668,696
Ensembl chr 7:73,531,486...73,784,067 		JBrowse link
G Ankk1 ankyrin repeat and kinase domain containing 1 susceptibility ISO DNA:polymorphism:exon:
DNA:SNP,haplotype:exon:rs1800497(human)		 RGD PMID:28574012 PMID:23443985 RGD:401959222, RGD:401959307 NCBI chr 8:58,676,327...58,685,012
Ensembl chr 8:49,779,862...49,788,024 		JBrowse link
G Ar androgen receptor severity ISO DNA:repeats:N-terminal
DNA:repeat, haplotype:exon		 RGD PMID:19231085 PMID:24271034 RGD:407424612, RGD:407550222 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Arrb2 arrestin, beta 2 IEP mRNA:decreased expression:nucleus accumbens RGD PMID:34919270 RGD:401938593 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Avp arginine vasopressin ISO
IEP		 protein:decreased expression:cerebrospinal fluid
protein:decreased expression:blood plasma
mRNA:increased expression:paraventricular nucleus of hypothalamus		 RGD PMID:7106059 PMID:15608610 PMID:9622448 RGD:408426006, RGD:596933105, RGD:529435544 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Avpr1b arginine vasopressin receptor 1B IEP RGD PMID:21309953 RGD:14700679 NCBI chr13:45,598,116...45,611,680
Ensembl chr13:43,046,267...43,057,792 		JBrowse link
G Bdnf brain-derived neurotrophic factor treatment
disease_progression
sexual_dimorphism 		IDA
ISO
IEP		 DNA:SNP: :66V>M
protein:altered expression:hippocampus		 RGD PMID:34453945 PMID:19170664 PMID:37303582 PMID:32579730 RGD:401959604, RGD:597830066, RGD:596936394, RGD:401959610 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 susceptibility ISO DNA:SNP::(rs6486120) (human) RGD PMID:20554694 RGD:401976551 NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:167,331,633...167,430,231 		JBrowse link
G Bmal2 basic helix-loop-helix ARNT like 2 susceptibility ISO DNA:SNPs, haplotype:: (rs7958822,rs4964057) (human) RGD PMID:20554694 RGD:401976551 NCBI chr 4:181,429,097...181,478,384
Ensembl chr 4:179,699,502...179,746,949 		JBrowse link
G Bptf bromodomain PHD finger transcription factor ISO associated with other drug dependencies; DNA:SNPs:CDS:intron (rs11870068) RGD PMID:27151647 RGD:405650603 NCBI chr10:92,480,007...92,582,485
Ensembl chr10:91,982,758...92,082,769 		JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C IEP mRNA, protein:increased expression:amygdala, hippocampus (rat)
protein:increased expression:inferior colliculus (human)		 RGD PMID:27905406 PMID:25556199 RGD:152985537, RGD:152985539 NCBI chr 4:153,431,169...154,051,932
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Cartpt CART prepropeptide susceptibility ISO DNA:polymorphism: :
DNA:SNP: : rs16871471		 RGD PMID:15234472 PMID:20362026 RGD:597805890, RGD:597805891 NCBI chr 2:32,989,215...32,991,794
Ensembl chr 2:31,255,098...31,290,713 		JBrowse link
G Cck cholecystokinin susceptibility ISO DNA:SNP:promoter: -45C>T (human) RGD PMID:9622381 RGD:407419865 NCBI chr 8:130,031,012...130,037,702
Ensembl chr 8:121,153,500...121,160,084 		JBrowse link
G Cdk20 cyclin-dependent kinase 20 susceptibility ISO DNA:SNP:: (rs560019) (human) RGD PMID:18438686 RGD:401851917 NCBI chr17:706,863...717,828
Ensembl chr17:701,124...707,826 		JBrowse link
G Ces1d carboxylesterase 1D ISO protein:decreased expression:white blood cell RGD PMID:8730217 RGD:597621688 NCBI chr19:30,046,494...30,085,039
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Chat choline O-acetyltransferase ISO protein:decreased expression:hippocampus,septum,striatum RGD PMID:8436061 RGD:401976285 NCBI chr16:7,663,665...7,723,416
Ensembl chr16:7,657,362...7,717,093 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit susceptibility ISO DNA:missense:exons:p.R37H,p.E363D(human) RGD PMID:24057674 RGD:405849397 NCBI chr 8:64,297,755...64,311,251
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit susceptibility ISO DNA:missense:exons:multiple(human) RGD PMID:24057674 RGD:405849397 NCBI chr16:71,411,847...71,454,225
Ensembl chr16:64,714,169...64,751,360 		JBrowse link
G Clock clock circadian regulator exacerbates ISO RGD PMID:23722243 RGD:401976471 NCBI chr14:32,262,747...32,346,872
Ensembl chr14:31,908,566...31,990,400 		JBrowse link
G Comt catechol-O-methyltransferase susceptibility
sexual_dimorphism
onset
disease_progression		 ISO associated with Alzheimer's disease; DNA:SNP:cd: P.V158M G>A (rs4680) (human)
DNA:SNPs,haplotypes:: (rs165774,rs4680) (human)
DNA:SNPs,haplotype:exon 4: p.V158M (rs4680) (human)
DNA:SNP:cd: p.V158M (rs4680) (human)
DNA:SNP:cd: p.V158M (human)
associated with major depressive disorder; DNA:SNP:cd: p.V158M (human)
DNA:polymorphism:exon 4: p.V158M (rs4680)(human)
associated with schizophrenia; DNA:promoter:Hypermethylation
associated with Trauma and Stressor Related Disorders ; DNA:polymorphism:exon: p.V158M (human)		 RGD PMID:25491588 PMID:22208661 PMID:16499480 PMID:24390676 PMID:16648777 More... RGD:11073926, RGD:401959747, RGD:401959300, RGD:401940156, RGD:401940155, RGD:401940149, RGD:401940148, RGD:401940146, RGD:401940133, RGD:401940131, RGD:401940120, RGD:401940118 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Cpe carboxypeptidase E ISO associated with other drug dependencies; DNA:SNPs:CDS:intron (rs10517844)
DNA:SNP:CDS: (rs13706874) (human)		 RGD PMID:27151647 PMID:20201924 RGD:405650603, RGD:405650609 NCBI chr16:29,796,707...29,908,647
Ensembl chr16:25,030,276...25,142,233 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 treatment ISO
IEP
IDA		 DNA:SNP:exon:rs35349697
protein:increased phosphorylation:prefrontal cortex (rat)
mRNA,protein:decreased expression:hippocampus		 RGD PMID:24704376 PMID:19324071 PMID:21951632 PMID:32579730 PMID:34453945 More... RGD:401938627, RGD:401901600, RGD:401959743, RGD:401959610, RGD:401959604, RGD:401959603 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 ISO protein:increased expression:brain RGD PMID:12354285 RGD:401901262 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 IDA RGD PMID:9927612 RGD:405650696 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 IDA RGD PMID:9927612 RGD:405650696 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 IDA RGD PMID:9927612 RGD:405650696 NCBI chr12:14,369,950...14,398,803
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Dbi diazepam binding inhibitor susceptibility
no_association		 ISO DNA:SNP:: +529A>T (rs8192503) (human)
DNA:SNP:: +529A>T (human)
DNA:SNP:: (rs2276596) (human)		 RGD PMID:18240651 PMID:21226341 PMID:24818357 RGD:408346758, RGD:408361841, RGD:408346759 NCBI chr13:33,794,231...33,802,632
Ensembl chr13:31,206,988...31,268,693 		JBrowse link
G Dgcr8 DGCR8 microprocessor complex subunit susceptibility ISO DNA:SNP:3���-UTR:G>T(rs1640299)(human) RGD PMID:25495208 RGD:401900681 NCBI chr11:96,208,959...96,241,560
Ensembl chr11:82,704,729...82,737,242 		JBrowse link
G Drd1 dopamine receptor D1 IMP RGD PMID:17360123 RGD:405100958 NCBI chr17:10,545,488...10,550,029
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 onset
susceptibility		 ISO DNA:insertion, deletion:promoter:
DNA:SNP: :rs1800498(human)		 RGD PMID:23238469 PMID:36825486 RGD:401959213, RGD:401959301 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd4 dopamine receptor D4 no_association ISO DNA:repeats:exon: RGD PMID:9342196 RGD:401959738 NCBI chr 1:205,825,937...205,829,124
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 susceptibility ISO
IEP		 associated with stress-related disorder;DNA:SNP:: (rs1360780) (human)
associated with stress-related disorder;mRNA:affects expression:ventral tegmental area,cingulate cortex, nucleus accumbens( rat)
DNA:SNPs:intron,3'utr: (rs1360780, rs3800373)		 RGD PMID:27527158 PMID:27709495 PMID:27709495 PMID:27527158 RGD:401976484, RGD:401976487, RGD:401976487, RGD:401976484 NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,457,216...6,541,674 		JBrowse link
G Fmn1 formin 1 ISO associated with other drug dependencies; DNA:SNPs:CDS: (rs3910705) RGD PMID:27151647 RGD:405650603 NCBI chr 3:120,555,445...120,939,978
Ensembl chr 3:100,134,549...100,479,220 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit treatment IDA
IEP		 protein:increased expression:granular insular cortex, paraventricular nucleus of thalamus, prefrontal cortex RGD PMID:29926762 PMID:17723286 PMID:14574439 PMID:17360123 RGD:405100722, RGD:405295497, RGD:405101697, RGD:405100958 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit treatment IEP protein:increased expression:nucleus accumbens (rat)
associated with Sleep Deprivation;protein:increased expression:brain		 RGD PMID:20626732 PMID:19324071 PMID:33662520 RGD:401851075, RGD:401901600, RGD:401900733 NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase susceptibility
severity		 ISO DNA:SNP:5'utr: -93A>G (rs45490695) (human)
DNA:SNP:5'utr: T137346C (human)		 RGD PMID:18849153 PMID:14675807 RGD:408345238, RGD:408345249 NCBI chr20:44,322,635...44,514,498
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 susceptibility
treatment		 ISO
IMP
HEP		 DNA:SNP, haplotype:intron: C>G (rs29220) (human)
DNA:SNP:Exon 11: T1974C (Human)
mRNA:decreased expression:hippocampus (rat)
DNA:SNP:intron: (rs29220) (human)
DNA:SNP:intron: (rs29253) (human)		 RGD PMID:26727527 PMID:36095322 PMID:36095322 PMID:10412185 PMID:22253714 More... RGD:11552767, RGD:401976442, RGD:401976442, RGD:401959601, RGD:401900163, RGD:401940102, RGD:401940100 NCBI chr20:1,469,779...1,499,352
Ensembl chr20:1,464,534...1,493,994 		JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 HEP mRNA:decreased expression:hippocampus (rat) RGD PMID:22253714 RGD:401900163 NCBI chr 5:65,743,073...66,083,695
Ensembl chr 5:60,947,526...61,288,104 		JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 ISO ClinVar Annotator: match by term: Alcohol dependence ClinVar
OMIM		 PMID:25741868 PMID:28492532 NCBI chr14:37,451,218...37,587,458
Ensembl chr14:37,097,279...37,228,944 		JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 susceptibility ISO DNA:SNPs: : RGD PMID:14745296 RGD:405866351 NCBI chr 1:117,602,772...117,838,230
Ensembl chr 1:108,296,124...108,698,961 		JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 ISO
HEP		 DNA:SNPs, haplotype:introns:IVS9+99C>A, IVS10+3145A>G (rs211014, rs211013) (human)
mRNA:decreased expression:hippocampus (human)
mRNA:increased expression:hippocampus (rat)		 RGD PMID:15630072 PMID:22253714 PMID:22253714 RGD:402463959, RGD:401900163, RGD:401900163 NCBI chr10:26,876,926...26,965,523
Ensembl chr10:26,374,694...26,464,346 		JBrowse link
G Gad1 glutamate decarboxylase 1 susceptibility
onset		 ISO DNA:SNPs, haplotype:5'UTR,IVS:Rs3749034,Rs2270335,Rs10439259(human)
DNA:SNPs: haplotype:multiple:rs1978340(human)		 RGD PMID:17067345 PMID:19111404 RGD:401900127, RGD:401900129 NCBI chr 3:75,777,260...75,818,099
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gad2 glutamate decarboxylase 2 susceptibility ISO DNA:SNP::-243A>G (rs2236418) RGD PMID:17034009 RGD:401900120 NCBI chr17:89,671,718...89,734,246
Ensembl chr17:84,763,628...84,826,155 		JBrowse link
G Gdnf glial cell derived neurotrophic factor treatment IMP
IDA
ISO		 protein:decreased expression:serum RGD PMID:15659598 PMID:19232578 PMID:20553781 PMID:24801661 RGD:405820207, RGD:405850246, RGD:405849399, RGD:405849388 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Gemin4 gem (nuclear organelle) associated protein 4 susceptibility ISO DNA:SNP:Promoter:C>T(rs910924)(human) RGD PMID:25495208 RGD:401900681 NCBI chr10:61,560,172...61,571,765
Ensembl chr10:61,066,425...61,073,431
Ensembl chr10:61,066,425...61,073,431 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 IEP protein:increased activity:plasma,liver,intestine: RGD PMID:6113606 RGD:14701046 NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,700...13,108,442 		JBrowse link
G Gpsm1 G-protein signaling modulator 1 ameliorates IMP RGD PMID:18719114 RGD:597830124 NCBI chr 3:29,538,929...29,565,921
Ensembl chr 3:9,128,636...9,167,827 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 ameliorates ISO RGD PMID:33955100 RGD:405649731 NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A susceptibility
ameliorates		 ISO DNA:repeats:promoter:(GT)n
DNA:mutation:cds:A825W(mouse)		 RGD PMID:21507155 PMID:33052417 PMID:29953905 RGD:401938633, RGD:401938638, RGD:401938635 NCBI chr10:6,136,458...6,560,003
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Grm8 glutamate metabotropic receptor 8 susceptibility ISO DNA:SNPs:intron 1: (rs886003, rs17862325) (human) RGD PMID:25978827 RGD:11070870 NCBI chr 4:56,771,247...57,696,951
Ensembl chr 4:55,805,955...56,730,831 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 ISO RGD PMID:29582627 RGD:14700988 NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G Hmgb1 high mobility group box 1 ISO protein:increased expression:orbitofrontal cortex RGD PMID:23206318 RGD:7175526 NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISO mRNA:increased expression:Brodmann (1909) area 9
associated with nicotine dependence;DNA:SNPs:enhancer:multiple
DNA:SNP: :140G>C		 RGD PMID:22176604 PMID:23216389 PMID:19060480 RGD:401900608, RGD:405849412, RGD:401900293 NCBI chr 2:38,427,169...38,431,733
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B susceptibility
onset
sexual_dimorphism
no_association		 ISO DNA:SNP:5'UTR:-161A>T (human)
DNA:SNP: :861G>C (human)
DNA:SNP: :861G>C(human)
DNA:SNP,haplotype:promoter:161A>T (human)
DNA:SNP:promoter:rs11568817 (human) 		RGD PMID:12022963 PMID:21906503 PMID:11104852 PMID:11827742 PMID:21172311 More... RGD:405650693, RGD:405847406, RGD:405847401, RGD:405818273, RGD:405650698, RGD:405650694 NCBI chr 8:91,395,405...91,414,815
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A disease_progression
treatment
no_association		 ISO
IMP
IEP		 DNA:SNP: :102T>C (rs6313)
protein:decreased expression:agranular insular cortex, cingulate cortex, frontal cortex
DNA:SNP:promoter:-1438G>A (rs6311)		 RGD PMID:23321485 PMID:8822536 PMID:15080502 PMID:19328219 PMID:19060480 More... RGD:401900291, RGD:401900739, RGD:401900737, RGD:401900304, RGD:401900293, RGD:401900297 NCBI chr15:56,360,647...56,428,703
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A exacerbates
treatment
susceptibility		 ISO
IEP		 mRNA:increased expression:peripheral blood mononuclear cell (human)
DNA:SNPs:enhancer, exon: (rs1150226, rs1176713) (human)
DNA:SNPs, haplotype:multiple (human)
mRNA:increased expression:prefrontal cortex (rat)
DNA:SNP:exon 1: (rs33940208) (human)		 RGD PMID:27144979 PMID:23897038 PMID:24590108 PMID:25722691 PMID:23757001 RGD:404976874, RGD:405096433, RGD:404976878, RGD:404976876, RGD:404976875 NCBI chr 8:58,138,514...58,150,960
Ensembl chr 8:49,242,020...49,254,389 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO protein:increased expression:blood RGD PMID:14634483 RGD:405878079 NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Kcnb2 potassium voltage-gated channel subfamily B member 2 ISO associated with other drug dependencies; DNA:SNPs:CDS:intron (rs2251898) RGD PMID:27151647 RGD:405650603 NCBI chr 5:8,340,085...8,811,184
Ensembl chr 5:3,569,685...4,028,599 		JBrowse link
G Lep leptin severity IDA
ISO
IEP		 DNA:hypermethylation:promoter
DNA:hypomethylation:promoter
protein:decreased expression:serum		 RGD PMID:29912265 PMID:30650427 PMID:19884906 PMID:29912265 RGD:21201248, RGD:407572512, RGD:407424613, RGD:21201248 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 treatment IDA RGD PMID:34453945 RGD:401959604 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 treatment IDA RGD PMID:34453945 RGD:401959604 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mc4r melanocortin 4 receptor treatment IMP RGD PMID:24635847 RGD:407572518 NCBI chr18:62,689,798...62,691,685
Ensembl chr18:60,419,832...60,421,719 		JBrowse link
G Ncam1 neural cell adhesion molecule 1 susceptibility ISO DNA:SNPs:exon: RGD PMID:17761687 RGD:405866369 NCBI chr 8:58,762,088...59,062,131
Ensembl chr 8:49,865,633...50,166,014 		JBrowse link
G Ngf nerve growth factor ISO
IEP		 protein:increased expression:serum
protein:decreased expression:sciatic nerve
protein:decreased expression:plasma		 RGD PMID:17434673 PMID:8733743 PMID:16737466 RGD:401965399, RGD:401976493, RGD:401965409 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Ngfr nerve growth factor receptor IEP protein:altered expression:brain,neuron RGD PMID:7609866 RGD:401976553 NCBI chr10:81,012,077...81,030,305
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Nkain2 sodium/potassium transporting ATPase interacting 2 susceptibility ISO DNA:SNP: :rs637547 (human) RGD PMID:21445666 RGD:596938167 NCBI chr 1:26,488,381...27,696,134
Ensembl chr 1:24,669,462...25,877,064 		JBrowse link
G Npy neuropeptide Y susceptibility ISO DNA:SNP:cd: p.L7P (rs16139) (human) RGD PMID:20554694 RGD:401976551 NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 treatment IMP
ISO		 RGD PMID:25886852 PMID:26121746 RGD:408345235, RGD:408345252 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 IEP mRNA:altered expression:central amygdaloid nucleus (rat) RGD PMID:28461696 RGD:401960064 NCBI chr19:47,619,853...47,964,089
Ensembl chr19:30,715,648...31,059,885 		JBrowse link
G Nrm nurim ISO associated with other drug dependencies; DNA:SNPs:CDS:intron (rs2269705) RGD PMID:27151647 RGD:405650603 NCBI chr20:2,893,126...2,897,725
Ensembl chr20:2,877,567...2,891,802 		JBrowse link
G Nrxn3 neurexin 3 susceptibility ISO DNA:SNP,haplotype:Chr14:rs8019381, rs760288|rs8019381|2rs2293847 (human) RGD PMID:17804423 RGD:405096431 NCBI chr 6:113,372,667...115,004,073
Ensembl chr 6:107,641,780...109,272,044 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 onset ISO DNA:SNPs: :rs993315, rs10780691
DNA:SNP: :rs1439047		 RGD PMID:17200667 PMID:28512340 RGD:408395149, RGD:596933091 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Ntsr1 neurotensin receptor 1 susceptibility ISO DNA:SNPs,haplotype::rs6011914,rs2427422(human) RGD PMID:23743782 RGD:596948429 NCBI chr 3:187,983,778...188,033,934
Ensembl chr 3:167,606,215...167,656,377 		JBrowse link
G Nucb2 nucleobindin 2 IEP mRNA,protein:decreased expression:hippocampus RGD PMID:37031608 RGD:401959603 NCBI chr 1:180,185,121...180,221,644
Ensembl chr 1:170,750,877...170,787,353 		JBrowse link
G Oprd1 opioid receptor, delta 1 ISO DNA:SNP,haplotype:intron 1 (rs2298896|rs421300), multiple GCAAT (human) RGD PMID:17622222 RGD:401976552 NCBI chr 5:149,590,244...149,624,999
Ensembl chr 5:144,306,188...144,340,960 		JBrowse link
G Oprk1 opioid receptor, kappa 1 no_association ISO DNA:SNPs:intron:multiple
DNA:SNP,haplotype:multiple (multiple GGCTTCT) (human)
mRNA:increased expression:orbitofrontal cortex
DNA:SNP: :rs6473797 (human)		 RGD PMID:16924269 PMID:17622222 PMID:21955155 PMID:24035285 RGD:401850571, RGD:401976552, RGD:401850584, RGD:401850579 NCBI chr 5:18,657,866...18,675,671
Ensembl chr 5:13,860,021...13,877,823 		JBrowse link
G Oprm1 opioid receptor, mu 1 no_association
treatment
sexual_dimorphism		 ISO DNA:missense mutation:exon:p.N40D (118A>G) (rs 1799971) (human)
DNA:SNP: :rs1799971 (human)		 RGD PMID:16679777 PMID:24035285 PMID:30748046 PMID:11424981 PMID:35992511 More... RGD:401827936, RGD:401850579, RGD:401831038, RGD:401827953, RGD:401827952, RGD:401827944, RGD:11097488, RGD:401827938, RGD:401827938 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Oxtr oxytocin receptor treatment
susceptibility
ameliorates		 ISO
IMP		 associated with anxiety disorder; DNA:SNP:intron: (rs2254298) (human)
rat gene in mouse model		 RGD PMID:28150062 PMID:37520225 PMID:25449413 PMID:27306084 RGD:597538533, RGD:597538604, RGD:597538598, RGD:597015745 NCBI chr 4:147,154,374...147,171,723
Ensembl chr 4:145,599,561...145,614,674 		JBrowse link
G Pde4b phosphodiesterase 4B susceptibility ISO DNA:SNP:: (rs1937443) (human) RGD PMID:18438686 RGD:401851917 NCBI chr 5:122,028,956...122,598,267
Ensembl chr 5:116,799,971...117,367,696 		JBrowse link
G Pdyn prodynorphin no_association
disease_progression		 ISO DNA:SNP, hypermethylation:promoter:rs2235751 (human)
mRNA, protein:increased expression:dorsolateral prefrontal cortex, orbitofrontal cortex
DNA:SNP: :rs1997794 (human)
DNA:SNP, hypermethylation:dorsolateral prefrontal cortex:rs2281285 (human)
DNA:SNP: :rs2281285 (human)
DNA:SNPs: :multiple
DNA:SNPs, haplotypes:multiple		 RGD PMID:28336495 PMID:21955155 PMID:24035285 PMID:21521424 PMID:26502829 More... RGD:401850551, RGD:401850584, RGD:401850579, RGD:401850575, RGD:11535796, RGD:401850571, RGD:401850565, RGD:401850560 NCBI chr 3:137,354,161...137,366,503
Ensembl chr 3:116,900,992...116,913,334 		JBrowse link
G Per2 period circadian regulator 2 ISO DNA, mRNA:hypermethylation, decreased expression:blood
DNA:hypermethylation:blood, promoter		 RGD PMID:30597578 PMID:31329297 RGD:405878075, RGD:405878078 NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:92,007,296...92,049,459 		JBrowse link
G Pknox2 PBX/knotted 1 homeobox 2 ISO associated with other drug dependencies; DNA:SNPs:CDS:intron (rs750338) RGD PMID:27151647 RGD:405650603 NCBI chr 8:44,789,464...45,051,933
Ensembl chr 8:36,600,636...36,790,940 		JBrowse link
G Pomc proopiomelanocortin no_association ISO
IDA
IEP		 DNA:SNP: :rs934778 (human)
DNA:hypermethylation:promoter:blood
mRNA:decreased expression:hypothalamus
mRNA:increased expression:pituitary gland
mRNA:increased expression:blood, lymphocyte
DNA:hypermethylation:blood, promoter
DNA, mRNA:hypermethylation, decreased expression:blood
mRNA:increased expression:blood, lymphocytes		 RGD PMID:24035285 PMID:24635847 PMID:20191296 PMID:11981131 PMID:7662043 More... RGD:401850579, RGD:407572518, RGD:407431644, RGD:407424597, RGD:406179436, RGD:405878079, RGD:405878078, RGD:405878075, RGD:405878074 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Prl prolactin treatment ISO RGD PMID:11418230 RGD:401959332 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 susceptibility ISO DNA:SNPs,haplotypes:multiple RGD PMID:20430014 RGD:597830074 NCBI chr13:84,469,593...84,475,884
Ensembl chr13:81,936,775...81,943,068 		JBrowse link
G Rgs6 regulator of G-protein signaling 6 ISO associated with other drug dependencies; DNA:SNPs:CDS: (rs11621871) RGD PMID:27151647 RGD:405650603 NCBI chr 6:107,875,883...108,527,472
Ensembl chr 6:102,264,447...102,824,753 		JBrowse link
G Slc29a1 solute carrier family 29 member 1 ISS OMIM:103780 MouseDO NCBI chr 9:22,897,099...22,911,640
Ensembl chr 9:15,399,612...15,414,203 		JBrowse link
G Slc6a1 solute carrier family 6 member 1 susceptibility ISO DNA:insertion:promoter:: (human) RGD PMID:26727527 RGD:11552767 NCBI chr 4:149,004,447...149,037,840
Ensembl chr 4:147,466,965...147,482,293 		JBrowse link
G Slc6a2 solute carrier family 6 member 2 susceptibility ISO DNA:SNPs,haplotypes:intron: (rs36020,rs36029) (human) RGD PMID:21070505 RGD:401976462 NCBI chr19:30,183,289...30,228,292
Ensembl chr19:14,010,386...14,050,357 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 disease_progression ISO DNA:VNTR RGD PMID:18552399 RGD:401900298 NCBI chr10:62,322,688...62,357,060
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 ISO DNA:SNP:exon:rs248793(human) RGD PMID:21323680 RGD:597621634 NCBI chr 1:35,514,914...35,548,898
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Tas2r118 taste receptor, type 2, member 118 susceptibility ISO OMIM NCBI chr 4:53,414,815...53,415,714
Ensembl chr 4:52,449,208...52,450,107 		JBrowse link
G Tbx19 T-box transcription factor 19 susceptibility ISO DNA:SNP:: (rs1003502) (human) RGD PMID:18438686 RGD:401851917 NCBI chr13:79,983,935...80,016,219
Ensembl chr13:77,450,849...77,504,163 		JBrowse link
G Tlr2 toll-like receptor 2 ISO protein:increased expression:orbitofrontal cortex RGD PMID:23206318 RGD:7175526 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr3 toll-like receptor 3 ISO protein:increased expression:orbitofrontal cortex RGD PMID:23206318 RGD:7175526 NCBI chr16:53,554,916...53,572,321
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr4 toll-like receptor 4 ISO protein:increased expression:orbitofrontal cortex RGD PMID:23206318 RGD:7175526 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tph2 tryptophan hydroxylase 2 no_association ISO DNA:SNP, haplotypes: :multiple
DNA:SNP:promoter:-703G>T
associated with alcohol dependence;DNA:SNPs, haplotypes: :multiple		 RGD PMID:26232682 PMID:18405071 PMID:17251907 RGD:597621681, RGD:597830065, RGD:597621693 NCBI chr 7:52,571,909...52,676,305
Ensembl chr 7:50,685,694...50,789,424 		JBrowse link
G Ttc12 tetratricopeptide repeat domain 12 susceptibility ISO DNA:SNPs:introns,exon: RGD PMID:17761687 RGD:405866369 NCBI chr 8:58,696,381...58,743,857
Ensembl chr 8:49,799,920...49,847,087 		JBrowse link
Alcohol Myopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 IEP RGD PMID:14506614 RGD:1581765 NCBI chr 1:190,457,198...190,475,410
Ensembl chr 1:181,026,608...181,044,838 		JBrowse link
alcohol use disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acads acyl-CoA dehydrogenase short chain susceptibility ISO DNA:SNP:: (rs1799958) (human) RGD PMID:20554694 RGD:401976551 NCBI chr12:47,154,259...47,163,580
Ensembl chr12:41,493,626...41,502,898 		JBrowse link
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:16404797 NCBI chr 2:229,470,703...229,482,291
Ensembl chr 2:226,797,303...226,808,892 		JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide IMP RGD PMID:8462548 RGD:5129091 NCBI chr 2:229,648,557...229,660,964
Ensembl chr 2:226,947,466...226,987,591 		JBrowse link
G Ager advanced glycosylation end product-specific receptor treatment
onset		 IEP
ISO		 protein:increased expression:frontal cortex neuron
protein:increased expression:orbitofrontal cortex
mRNA, protein:increased expression:orbitofrontal cortex, neurons		 RGD PMID:33716687 PMID:32664441 PMID:23867237 PMID:23867237 PMID:23867237 RGD:597538457, RGD:597805903, RGD:597538460, RGD:597538460, RGD:597538460 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16404797 PMID:17590986 PMID:10780266 RGD:734551 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Ankk1 ankyrin repeat and kinase domain containing 1 severity ISO DNA:polymorphism: :rs1800497(human)
DNA:SNP,haplotype: :rs11604671, rs4938015 (human)		 RGD PMID:32889058 PMID:21936764 RGD:401940151, RGD:401959296 NCBI chr 8:58,676,327...58,685,012
Ensembl chr 8:49,779,862...49,788,024 		JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 ISO DNA, mRNA, protein:hypermethylation, decreased expression:brain RGD PMID:31239533 RGD:407987270 NCBI chr 7:10,043,010...10,065,037
Ensembl chr 7:9,392,336...9,414,310 		JBrowse link
G App amyloid beta precursor protein IEP protein:increased expression:liver RGD PMID:36187787 RGD:597830170 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein ISO associated with Prenatal Exposure Delayed Effects and anxiety disorder:DNA:Hypermthylation:promoter RGD PMID:30016666 RGD:401959614 NCBI chr 7:108,444,959...108,448,413
Ensembl chr 7:106,555,785...106,559,378 		JBrowse link
G Avp arginine vasopressin IEP mRNA:altered expression:central amygdaloid nucleus, medial amygdaloid nucleus, medial zone of hypothalamus
protein:decreased expression:suprachiasmatic nucleus		 RGD PMID:21575018 PMID:11709626 RGD:408364978, RGD:596933084 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Bdnf brain-derived neurotrophic factor treatment IEP
ISO		 protein:decreased expression:plasma
mRNA, protein:altered expression:brain
protein:decreased expression:cerebellum, hippocampus
mRNA,protein:decreased expression:hippocampus, plasma (rat)
protein:decreased expression:plasma (human)		 RGD PMID:32135570 PMID:32330588 PMID:33919862 PMID:19100286 PMID:15307153 More... RGD:35673317, RGD:596936412, RGD:596933362, RGD:401976492, RGD:401965482, RGD:401938665, RGD:401938665 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Calb1 calbindin 1 IEP mRNA:decreased expression:hippocampus (rat) RGD PMID:30277635 RGD:401938665 NCBI chr 5:34,172,612...34,199,555
Ensembl chr 5:29,375,642...29,402,431 		JBrowse link
G Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 ISO mRNA:increased expression:prefrontal cortex RGD PMID:28714806 RGD:18337277 NCBI chr 5:155,958,116...155,959,897
Ensembl chr 5:150,673,507...150,676,600 		JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV IEP protein:decreased expression:brain, cingulate gyrus RGD PMID:11181917 RGD:401959326 NCBI chr18:24,857,152...25,076,054
Ensembl chr18:24,585,269...24,802,487 		JBrowse link
G Cartpt CART prepropeptide susceptibility ISO DNA:SNPs: : rs11575893,rs16871471 RGD PMID:20362026 RGD:597805891 NCBI chr 2:32,989,215...32,991,794
Ensembl chr 2:31,255,098...31,290,713 		JBrowse link
G Cast calpastatin IEP protein:increased expression:gastrocnemius (rat) RGD PMID:28800153 RGD:405100967 NCBI chr 2:5,707,633...5,817,213
Ensembl chr 2:3,973,112...4,082,659 		JBrowse link
G Cat catalase treatment IEP associated with diabetes; protein:decreased activity;testis, epididymis (rat)
associated with cardiomyopathy
associated with cognitive disorder; protein:altered activity:hippocampus (rat)
associated with diabetes;protein:decreased activity:liver, kidney (rat)		 RGD PMID:22596042 PMID:25541261 PMID:7195942 PMID:27367870 PMID:21713042 RGD:405255659, RGD:405255664, RGD:405255663, RGD:405255662, RGD:405255660 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cckar cholecystokinin A receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:9922984 NCBI chr14:61,505,270...61,513,618
Ensembl chr14:57,292,397...57,300,747 		JBrowse link
G Cdk20 cyclin-dependent kinase 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438686 NCBI chr17:706,863...717,828
Ensembl chr17:701,124...707,826 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:18414406 NCBI chr 8:64,297,755...64,311,251
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:18414406 NCBI chr 8:64,265,879...64,294,233
Ensembl chr 8:55,369,794...55,398,146 		JBrowse link
G Chrna6 cholinergic receptor nicotinic alpha 6 subunit severity ISO DNA:haplotypes: : RGD PMID:19698703 RGD:405849410 NCBI chr16:71,400,615...71,407,315
Ensembl chr16:64,697,741...64,704,441 		JBrowse link
G Clock clock circadian regulator susceptibility ISO DNA:SNP:: (rs2412648) (human) RGD PMID:20554694 RGD:401976551 NCBI chr14:32,262,747...32,346,872
Ensembl chr14:31,908,566...31,990,400 		JBrowse link
G Cnr1 cannabinoid receptor 1 sexual_dimorphism IEP associated with chronic stress in female rats RGD PMID:27894930 RGD:401959751 NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Comt catechol-O-methyltransferase disease_progression ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphism: :rs4680(human)
DNA:polymorphism::		 CTD
RGD		 PMID:10395222 PMID:32889058 PMID:10395222 RGD:401940151, RGD:401940114 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 sexual_dimorphism IEP
IDA		 mRNA, protein:decreased expression:amygdala
protein:increased phosphorylation:liver
protein:altered expression, altered phosphorylation:liver, nucleus		 RGD PMID:29991681 PMID:31262967 PMID:22269225 RGD:401938626, RGD:401959334, RGD:401959317 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crebbp CREB binding protein IEP mRNA, protein:decreased expression:amygdala RGD PMID:29991681 RGD:401938626 NCBI chr10:11,842,307...11,968,266
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Crh corticotropin releasing hormone IEP mRNA:increased expression:central amygdaloid nucleus (rat) RGD PMID:20060104 RGD:5508173 NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO RGD PMID:11988580 RGD:734822 NCBI chr10:89,540,192...89,583,466
Ensembl chr10:89,040,203...89,083,481 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO
IEP		 CTD Direct Evidence: marker/mechanism
protein:increased expression:plasma, extracellular exosome		 CTD
RGD		 PMID:20843640 PMID:23819932 PMID:29404485 PMID:29404485 RGD:14700915, RGD:14700911, RGD:14700911 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Dbh dopamine beta-hydroxylase no_association ISO DNA:polymorphism:5' utr:g.-1021C>T (human)
DNA:polymorphism:cds:g.444G>A (human)		 RGD PMID:16133787 PMID:16252068 RGD:1625572, RGD:1625571 NCBI chr 3:30,886,313...30,903,313
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Dbi diazepam binding inhibitor ISO mRNA,protein:increased expression:cerebral cortex (mouse) RGD PMID:9526063 RGD:408346747 NCBI chr13:33,794,231...33,802,632
Ensembl chr13:31,206,988...31,268,693 		JBrowse link
G Dcx doublecortin IEP mRNA:decreased expression:hippocampus (rat) RGD PMID:30277635 RGD:401938665 NCBI chr  X:112,227,455...112,370,291
Ensembl chr  X:107,430,767...107,507,476 		JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 ISO associated with Prenatal Exposure Delayed Effects and anxiety disorder:mRNA,protein:decreased expression:brain (mouse) RGD PMID:30016666 RGD:401959614 NCBI chr10:55,239,397...55,267,780
Ensembl chr10:54,739,470...54,767,153 		JBrowse link
G Drd2 dopamine receptor D2 IEA GAD PMID:15118671 RGD:1331525 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd4 dopamine receptor D4 treatment
susceptibility		 ISO DNA:repeats:exon:
associated with peer pressure;DNA:repeats:exon:		 RGD PMID:25640830 PMID:26307243 RGD:11064848, RGD:401959598 NCBI chr 1:205,825,937...205,829,124
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Ep300 E1A binding protein p300 IEP mRNA, protein:decreased expression:amygdala RGD PMID:29991681 RGD:401938626 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit IEP RGD PMID:23095216 RGD:10045658 NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Fgf2 fibroblast growth factor 2 IMP RGD PMID:28821667 PMID:31375540 RGD:405855870, RGD:405855874 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 IEP mRNA:increased expression:cerebellum RGD PMID:34453331 RGD:401938639 NCBI chr  X:152,284,857...152,322,686
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit treatment IEP
IDA
ISO		 protein:increased expression:brain
protein:increased expression:parvocellular oculomotor nucleus 		RGD PMID:14741756 PMID:29210146 PMID:11164784 RGD:405255650, RGD:405295495, RGD:405255652 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit treatment IEP
ISO		 protein:increased expression:dorsal striatum (mouse)
protein:increased expression:brain (mouse)		 RGD PMID:22792289 PMID:27380261 PMID:9835277 RGD:401851082, RGD:401901287, RGD:401901184 NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Fshb follicle stimulating hormone subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:8590623 NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22253714 NCBI chr20:1,469,779...1,499,352
Ensembl chr20:1,464,534...1,493,994 		JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 susceptibility ISO DNA:SNP:intron: (rs2900512) (human) RGD PMID:28118741 RGD:401940105 NCBI chr 5:65,743,073...66,083,695
Ensembl chr 5:60,947,526...61,288,104 		JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 susceptibility ISO DNA:SNPs:multiple:
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:22253714 PMID:15024690 RGD:6480257 NCBI chr14:37,451,218...37,587,458
Ensembl chr14:37,097,279...37,228,944 		JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 susceptibility ISO DNA:CA repeats: :(human) RGD PMID:9858031 RGD:405866342 NCBI chr 1:117,602,772...117,838,230
Ensembl chr 1:108,296,124...108,698,961 		JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22253714 NCBI chr10:26,876,926...26,965,523
Ensembl chr10:26,374,694...26,464,346 		JBrowse link
G Gata4 GATA binding protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20585342 NCBI chr15:41,635,572...41,707,252
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Gdnf glial cell derived neurotrophic factor treatment ISO
IEP
IDA		 protein:increased expression:serum
associated with Tobacco Use Disorder;mRNA:decreased expression:ventral tegmental area
DNA:hypomethylation:nucleus accumbens		 RGD PMID:25623403 PMID:28559549 PMID:22238721 PMID:31710958 RGD:401965480, RGD:405850249, RGD:405849387, RGD:405820205 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12747453 NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,700...13,108,442 		JBrowse link
G Ghsr growth hormone secretagogue receptor ISO CTD Direct Evidence: therapeutic CTD PMID:23977009 NCBI chr 2:112,196,158...112,201,666
Ensembl chr 2:110,268,489...110,271,865 		JBrowse link
G Gphn gephyrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:22253714 NCBI chr 6:102,687,405...103,216,679
Ensembl chr 6:96,892,148...97,483,612 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 ISO
IEP		 protein:increased phosphorylation:lumbar spinal cord (mouse)
protein:decreased expression:neocortex (rat)
protein:increased expression, increased phosphorylation:cingulate cortex (rat)
protein:increased expression:nucleus accumbens (mouse)
protein:increased expression:nucleus accumbens (rat)		 RGD PMID:28585190 PMID:12036520 PMID:34280506 PMID:21041654 PMID:21041654 RGD:405100727, RGD:405820203, RGD:405818275, RGD:405650686, RGD:405650686 NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 IEP protein:decreased expression:neocortex (rat)
protein:increased expression:ventral CA1 field of hippocampus (rat)		 RGD PMID:12036520 PMID:30481568 RGD:405820203, RGD:596933081 NCBI chr 2:168,247,490...168,367,616
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 ISO RGD PMID:14573320 RGD:1642372 NCBI chr 3:28,501,836...28,528,754
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B treatment ISO
IEP		 RGD PMID:14573320 PMID:32664441 PMID:16911840 RGD:1642372, RGD:597805903, RGD:1642200 NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Grm5 glutamate metabotropic receptor 5 treatment IEP RGD PMID:32664441 RGD:597805903 NCBI chr 1:150,722,711...151,297,585
Ensembl chr 1:141,312,368...141,882,274 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO DNA:SNP:: rs1695(human) RGD PMID:31886888 RGD:597621684 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Hdac2 histone deacetylase 2 IMP RGD PMID:23485013 RGD:9590265 NCBI chr20:42,101,815...42,126,486
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Hmgb1 high mobility group box 1 onset
treatment		 ISO
IEP		 protein:increased expression:orbitofrontal cortex
protein:increased expression:frontal cortex neuron		 RGD PMID:23867237 PMID:32664441 PMID:23867237 RGD:597538460, RGD:597805903, RGD:597538460 NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A treatment IMP RGD PMID:9631953 RGD:401900760 NCBI chr 2:38,427,169...38,431,733
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B sexual_dimorphism
onset
no_association		 ISO associated with attention deficit hyperactivity disorder;DNA:SNP: :rs11568817(human)
DNA:SNP: :rs13212041 (human)
DNA:SNPs: :multiples (human)		 RGD PMID:28923721 PMID:30774345 PMID:11496363 RGD:405650695, RGD:405847403, RGD:405818272 NCBI chr 8:91,395,405...91,414,815
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A treatment IEP
IMP		 mRNA, protein:decreased expression:cerebral cortex, liver
protein:increased expression:dorsal raphe, nucleus accumbens		 RGD PMID:20501057 PMID:9631953 PMID:9347073 PMID:9347075 RGD:401900301, RGD:401900760, RGD:401900742, RGD:401900740 NCBI chr15:56,360,647...56,428,703
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C treatment IDA RGD PMID:24041931 RGD:401900761 NCBI chr  X:115,453,190...115,682,325
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A ISO DNA:hypermethylation, hypomethylation:promoter: (mouse) RGD PMID:22834954 RGD:404976877 NCBI chr 8:58,138,514...58,150,960
Ensembl chr 8:49,242,020...49,254,389 		JBrowse link
G Htr3b 5-hydroxytryptamine receptor 3B susceptibility ISO DNA:SNP:cds:rs1176744(human) RGD PMID:20838391 RGD:6480660 NCBI chr 8:58,175,785...58,204,939
Ensembl chr 8:49,279,173...49,308,444 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 ISO DNA:SNP:intron: (rs7916403) (human) RGD PMID:21184583 RGD:150429835 NCBI chr 1:243,049,064...243,173,636
Ensembl chr 1:233,636,452...233,760,626 		JBrowse link
G Igf2 insulin-like growth factor 2 ISO protein:decreased expression:plasma (human) RGD PMID:30277635 RGD:401938665 NCBI chr 1:207,243,873...207,261,263
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Il10 interleukin 10 IEP mRNA:increased expression:liver RGD PMID:22269225 RGD:401959317 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il6 interleukin 6 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:26208141 RGD:11342768 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 ISO DNA:SNP:promoter:rs2836016 (human) RGD PMID:21307845 RGD:6483053 NCBI chr11:47,531,312...47,778,348
Ensembl chr11:34,061,708...34,308,758 		JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 IEP protein:decreased expression:ventral CA1 field of hippocampus (rat) RGD PMID:30481568 RGD:596933081 NCBI chr18:40,004,693...40,445,043
Ensembl chr18:37,817,957...38,258,347 		JBrowse link
G Lhb luteinizing hormone subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:8590623 NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972 		JBrowse link
G Lrp1 LDL receptor related protein 1 IEP protein:decreased expression:liver RGD PMID:36187787 RGD:597830170 NCBI chr 7:65,265,639...65,346,196
Ensembl chr 7:63,380,356...63,460,910 		JBrowse link
G Maoa monoamine oxidase A susceptibility ISO RGD PMID:15900229 RGD:1600720 NCBI chr  X:8,615,239...8,681,372
Ensembl chr  X:6,030,795...6,099,593 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 IEP protein:increased expression:liver RGD PMID:31262967 RGD:401959334 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 ISO protein:increased expression, increased phosphorylation:liver RGD PMID:31262967 RGD:401959334 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 IEP protein:increased expression:liver RGD PMID:31262967 RGD:401959334 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IDA RGD PMID:31262967 RGD:401959334 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mb myoglobin ISO protein:decreased expression:serum RGD PMID:3766421 RGD:458925288 NCBI chr 7:110,640,511...110,647,742
Ensembl chr 7:108,759,904...108,767,383 		JBrowse link
G Mcm5 minichromosome maintenance complex component 5 IEP RGD PMID:23095216 RGD:10045658 NCBI chr19:13,488,813...13,510,131
Ensembl chr19:13,483,066...13,504,389 		JBrowse link
G Mir191 microRNA 191 onset IEP RGD PMID:32135570 RGD:35673317 NCBI chr 8:118,142,627...118,142,717 JBrowse link
G Mir195 microRNA 195 onset IEP RGD PMID:32135570 RGD:35673317 NCBI chr10:55,450,495...55,450,581
Ensembl chr10:54,951,838...54,951,924 		JBrowse link
G Mir206 microRNA 206 onset IEP RGD PMID:32135570 RGD:35673317 NCBI chr 9:30,590,697...30,590,780
Ensembl chr 9:23,094,249...23,094,332 		JBrowse link
G Mir30a microRNA 30a onset IEP RGD PMID:32135570 RGD:35673317 NCBI chr 9:33,233,941...33,234,011
Ensembl chr 9:25,737,600...25,737,670 		JBrowse link
G Mki67 marker of proliferation Ki-67 IEP mRNA:decreased expression:hippocampus (rat) RGD PMID:30277635 RGD:401938665 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mmp2 matrix metallopeptidase 2 IEP RGD PMID:24966898 RGD:13207311 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 IEP RGD PMID:24966898 RGD:13207311 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Ncam1 neural cell adhesion molecule 1 sexual_dimorphism
treatment		 IEP mRNA:decreased expression:hippocampus (rat)
associated with chronic stress in female rats		 RGD PMID:30277635 PMID:27894930 PMID:16207289 RGD:401938665, RGD:401959751, RGD:401959613 NCBI chr 8:58,762,088...59,062,131
Ensembl chr 8:49,865,633...50,166,014 		JBrowse link
G Ngf nerve growth factor ISO
IEP		 protein:increased expression:serum
protein:decreased expression:cerebral cortex, hippocampus
protein:decreased expression:brain		 RGD PMID:25623403 PMID:19100286 PMID:15307153 RGD:401965480, RGD:401976492, RGD:401965482 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Npy neuropeptide Y IAGP
ISO		 DNA:deletion:intron:g.4666_4674del (rat)
CTD Direct Evidence: marker/mechanism
DNA:missense mutation: :p.L7P (human)		 CTD
RGD		 PMID:17572454 PMID:15749341 PMID:12215082 RGD:1357412, RGD:10430830 NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
G Npy2r neuropeptide Y receptor Y2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18828811 NCBI chr 2:170,200,027...170,210,286
Ensembl chr 2:167,903,879...167,905,024 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 treatment IDA
IEP
IMP		 protein:decreased expression, decreased DNA binding:brain
mRNA, protein:decreased expression:placenta		 RGD PMID:11961084 PMID:21143252 PMID:31756338 PMID:33920737 RGD:408345232, RGD:408345244, RGD:408345241, RGD:408345239 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 treatment
sexual_dimorphism		 IMP RGD PMID:29437012 PMID:30171933 PMID:33007359 RGD:401965466, RGD:401976281, RGD:401966865 NCBI chr19:47,619,853...47,964,089
Ensembl chr19:30,715,648...31,059,885 		JBrowse link
G Nrg1 neuregulin 1 sexual_dimorphism ISO in female, associated with stressful life event;DNA:SNP: :rs6994992(human) RGD PMID:27353026 RGD:405100235 NCBI chr16:65,954,084...67,007,484
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Ntf3 neurotrophin 3 ISO
IEP		 protein:decreased expression:plasma (human)
protein:increased expression:brain
mRNA,protein:decreased expression:hippocampus, plasma (rat)		 RGD PMID:30277635 PMID:15307153 PMID:30277635 RGD:401938665, RGD:401965482, RGD:401938665 NCBI chr 4:160,601,161...160,670,623
Ensembl chr 4:158,914,957...158,984,596 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 treatment ISO
IEP
IDA		 associated with Prenatal Exposure Delayed Effects and anxiety disorder:protein:decreased acetylation:brain RGD PMID:30016666 PMID:33919862 PMID:32206827 PMID:8840027 RGD:401959614, RGD:596933362, RGD:596933095, RGD:401965407 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Oprd1 opioid receptor, delta 1 IEP
ISO
IMP		 associated with stress-related disorder; mRNA:decreased expression:dorsal striatum (rat)
DNA:SNPs, haplotype:intron 1:multiple (human)		 RGD PMID:28511993 PMID:24533225 PMID:7501658 RGD:401976432, RGD:402525443, RGD:401976439 NCBI chr 5:149,590,244...149,624,999
Ensembl chr 5:144,306,188...144,340,960 		JBrowse link
G Oprk1 opioid receptor, kappa 1 severity
susceptibility
no_association		 ISO
IEP		 DNA:SNP, haplotype: :rs6473797 (human)
associated with stress-related disorder; mRNA:decreased expression:dorsal striatum (rat)
DNA:SNP: :rs6473797 (human)
DNA:SNP: :rs997917 (human)		 RGD PMID:31004399 PMID:28511993 PMID:37177778 PMID:37177778 RGD:401831037, RGD:401976432, RGD:401850581, RGD:401850581 NCBI chr 5:18,657,866...18,675,671
Ensembl chr 5:13,860,021...13,877,823 		JBrowse link
G Oprl1 opioid related nociceptin receptor 1 IMP RGD PMID:11814626 RGD:9835016 NCBI chr 3:189,209,495...189,225,406
Ensembl chr 3:168,834,003...168,839,920 		JBrowse link
G Oprm1 opioid receptor, mu 1 treatment
no_association		 ISO CTD Direct Evidence: marker/mechanism
DNA:missense mutation:exon:p.N40D (118A>G) (rs 1799971) (human)
DNA:missense mutations, SNP:exon, intron:p.A6V, p.S147C, p.N40D (118A>G) (rs 1799971), IVS2+691G>C (human)
DNA:SNP: :rs510769		 CTD
RGD		 PMID:12815747 PMID:32772383 PMID:9399694 PMID:26042510 RGD:401827947, RGD:401827934, RGD:401827930 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide disease_progression ISO mRNA:increased expression:prefrontal cortex, brain (human) RGD PMID:28787642 RGD:597621697 NCBI chr 3:138,235,754...138,236,594
Ensembl chr 3:117,782,650...117,783,490 		JBrowse link
G Oxtr oxytocin receptor sexual_dimorphism ISO DNA:SNP:intron: (rs53576) (human)
DNA:hypomethylation		 RGD PMID:27716573 PMID:35146961 RGD:597538589, RGD:597538605 NCBI chr 4:147,154,374...147,171,723
Ensembl chr 4:145,599,561...145,614,674 		JBrowse link
G Pde4b phosphodiesterase 4B ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438686 NCBI chr 5:122,028,956...122,598,267
Ensembl chr 5:116,799,971...117,367,696 		JBrowse link
G Pdyn prodynorphin no_association
susceptibility		 ISO
IEP		 CTD Direct Evidence: marker/mechanism
mRNA, protein:decreased expression:hippocampus, granule cell
DNA:SNPs: :rs2281285, rs2225749, rs910080 (human)
DNA:SNP: :rs2281285 (human)
DNA, mRNA:SNP, decreased expression:promoter, dorsolateral prefrontal cortex:rs1997794 (human)
associated with cocaine dependence;DNA, mRNA:SNPs, haplotype:3' utr:rs910080, rs910079, rs2235749 (human)		 CTD
RGD		 PMID:17559549 PMID:18923396 PMID:1589146 PMID:37177778 PMID:36099111 More... RGD:401851059, RGD:401850581, RGD:401850566, RGD:401850559, RGD:401850550 NCBI chr 3:137,354,161...137,366,503
Ensembl chr 3:116,900,992...116,913,334 		JBrowse link
G Penk proenkephalin IEP mRNA:increased expression:frontal lobe: RGD PMID:22703995 RGD:10003152 NCBI chr 5:21,981,381...21,987,074
Ensembl chr 5:17,183,806...17,189,129 		JBrowse link
G Per1 period circadian regulator 1 IEP mRNA:altered expression: arcuate nucleus of hypothalamus RGD PMID:15009656 RGD:407572515 NCBI chr10:54,299,002...54,313,804
Ensembl chr10:53,805,535...53,814,431 		JBrowse link
G Per2 period circadian regulator 2 IEP mRNA:altered expression: arcuate nucleus of hypothalamus, suprachiasmatic nucleus RGD PMID:15009656 RGD:407572515 NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:92,007,296...92,049,459 		JBrowse link
G Per3 period circadian regulator 3 IEP mRNA:altered expression:suprachiasmatic nucleus RGD PMID:15009656 RGD:407572515 NCBI chr 5:166,740,914...166,778,243
Ensembl chr 5:161,459,533...161,495,607 		JBrowse link
G Pomc proopiomelanocortin sexual_dimorphism IEP
ISO		 protein:decreased expression:brain (rat)
mRNA:altered expression: arcuate nucleus of hypothalamus
associated with Prenatal Exposure Delayed Effects;mRNA:altered expression:adenohypophysis
protein:increased expression:plasma
mRNA, protein:increased expression:arcuate nucleus, hypothalamus, septum
DNA, mRNA:deletion, decreased expression:enhancer, hypothalamus
mRNA:increased expression: hypothalamus, pituitary gland, shell of nucleus accumbens		 RGD PMID:18162070 PMID:15009656 PMID:19912941 PMID:19912941 PMID:7925590 More... RGD:401976284, RGD:407572515, RGD:407572513, RGD:407572513, RGD:407571692, RGD:407550221, RGD:405878072 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Rbfox1 RNA binding fox-1 homolog 1 sexual_dimorphism ISO DNA:SNPs:intron 1, 3: (rs8062784, rs12921846) (human) RGD PMID:33329073 RGD:597830062 NCBI chr10:8,658,809...10,754,648
Ensembl chr10:8,152,198...9,686,659 		JBrowse link
G Rest RE1-silencing transcription factor ISO protein:increased expression:basal forebrain RGD PMID:37402853 RGD:597538603 NCBI chr14:31,213,415...31,233,451
Ensembl chr14:30,862,553...30,894,354 		JBrowse link
G Rpl18a ribosomal protein L18A IEP mRNA:decreased expression:parietal cortex RGD PMID:11244494 RGD:11038708 NCBI chr16:18,576,467...18,578,653
Ensembl chr16:18,542,566...18,545,546
Ensembl chr 1:18,542,566...18,545,546 		JBrowse link
G Sell selectin L ISO protein:decreased expression:Tcell RGD PMID:7573774 RGD:597015763 NCBI chr13:78,950,100...78,969,604
Ensembl chr13:76,416,915...76,436,456 		JBrowse link
G Shbg sex hormone binding globulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:8590623 NCBI chr10:54,831,716...54,849,162
Ensembl chr10:54,332,941...54,351,057 		JBrowse link
G Slc1a2 solute carrier family 1 member 2 treatment IEP RGD PMID:32664441 RGD:597805903 NCBI chr 3:109,460,109...109,590,445
Ensembl chr 3:89,005,129...89,126,498 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27219321 NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 susceptibility ISO protein:decreased activity: :
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:15520362 PMID:17000009 PMID:20838391 RGD:6480660 NCBI chr10:62,322,688...62,357,060
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Snca synuclein alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:18055133 NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Sod1 superoxide dismutase 1 IEP associated with diabetes; protein:decreased activity;testis, epididymis (rat) RGD PMID:25541261 RGD:405255664 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sox2 SRY-box transcription factor 2 IEP mRNA:decreased expression:hippocampus (rat) RGD PMID:30277635 RGD:401938665 NCBI chr 2:119,465,131...119,467,542
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
G Spi1 Spi-1 proto-oncogene treatment IEP
IDA		 protein:decreased expression:alveolar macrophage RGD PMID:16272341 PMID:21447000 RGD:9586723, RGD:9586725 NCBI chr 3:97,529,509...97,548,204
Ensembl chr 3:77,073,012...77,092,393 		JBrowse link
G Spn sialophorin ISO associated with Prenatal Exposure Delayed Effects and anxiety disorder:DNA:Hypermthylation:promoter RGD PMID:30016666 RGD:401959614 NCBI chr 1:191,177,449...191,190,115
Ensembl chr 1:181,746,429...181,759,628 		JBrowse link
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 severity ISO mRNA,protein:decreased expression:liver: RGD PMID:17697868 RGD:10043133 NCBI chr11:91,031,481...91,158,111
Ensembl chr11:77,526,837...77,653,310 		JBrowse link
G Syp synaptophysin sexual_dimorphism IEP associated with chronic stress in female rats RGD PMID:27894930 RGD:401959751 NCBI chr  X:17,521,348...17,536,449
Ensembl chr  X:14,849,444...14,864,745 		JBrowse link
G Tacr1 tachykinin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19204064 NCBI chr 4:116,478,617...116,647,492
Ensembl chr 4:114,920,844...115,089,733 		JBrowse link
G Tacr3 tachykinin receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18422838 NCBI chr 2:225,940,497...226,037,756
Ensembl chr 2:223,266,536...223,363,791 		JBrowse link
G Tas2r118 taste receptor, type 2, member 118 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16385453 PMID:17250611 NCBI chr 4:53,414,815...53,415,714
Ensembl chr 4:52,449,208...52,450,107 		JBrowse link
G Tas2r138 taste receptor, type 2, member 138 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17250611 NCBI chr 4:70,395,042...70,396,037
Ensembl chr 4:69,428,344...69,429,339 		JBrowse link
G Tbx19 T-box transcription factor 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438686 NCBI chr13:79,983,935...80,016,219
Ensembl chr13:77,450,849...77,504,163 		JBrowse link
G Tf transferrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:11000917 PMID:21792595 NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:103,767,995...103,816,511 		JBrowse link
G Timeless timeless circadian regulator susceptibility ISO DNA:SNP:: (rs2291738) (human) RGD PMID:20554694 RGD:401976551 NCBI chr 7:1,239,388...1,263,344
Ensembl chr 7:654,822...678,738 		JBrowse link
G Tlr2 toll-like receptor 2 IEP
ISO		 protein:decreased expression:alveolar macrophage
mRNA:increased expression:orbitofrontal cortex
mRNA:increased expression:liver
protein:decreased expression:blood, monocyte
mRNA:increased expression:respiratory system fluid/secretion		 RGD PMID:36281822 PMID:34415075 PMID:30756376 PMID:27256567 PMID:26208141 RGD:597538461, RGD:597538499, RGD:597538493, RGD:597538485, RGD:11342768 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr3 toll-like receptor 3 ISO mRNA:increased expression:orbitofrontal cortex RGD PMID:34415075 RGD:597538499 NCBI chr16:53,554,916...53,572,321
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr4 toll-like receptor 4 onset ISO
IEP		 mRNA:decreased expression:respiratory system fluid/secretion
protein:increased expression:frontal cortex neuron
protein:increased expression:orbitofrontal cortex
mRNA:increased expression:orbitofrontal cortex
mRNA:increased expression:liver
protein:increased expression:liver
protein:decreased expression:blood, monocyte		 RGD PMID:26208141 PMID:23867237 PMID:23867237 PMID:34415075 PMID:30756376 More... RGD:11342768, RGD:597538460, RGD:597538460, RGD:597538499, RGD:597538493, RGD:150540306, RGD:597538485 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr5 toll-like receptor 5 ISO mRNA:increased expression:orbitofrontal cortex RGD PMID:34415075 RGD:597538499 NCBI chr13:97,166,430...97,190,642
Ensembl chr13:94,634,801...94,657,738 		JBrowse link
G Tlr6 toll-like receptor 6 ISO mRNA:increased expression:orbitofrontal cortex RGD PMID:34415075 RGD:597538499 NCBI chr14:43,715,809...43,727,019
Ensembl chr14:43,362,164...43,375,685 		JBrowse link
G Tlr7 toll-like receptor 7 ISO mRNA:increased expression:orbitofrontal cortex RGD PMID:34415075 RGD:597538499 NCBI chr  X:30,644,324...30,670,796
Ensembl chr  X:27,027,425...27,054,754 		JBrowse link
G Tlr8 toll-like receptor 8 ISO mRNA:increased expression:orbitofrontal cortex RGD PMID:34415075 RGD:597538499 NCBI chr  X:30,708,714...30,733,104
Ensembl chr  X:27,091,778...27,116,549 		JBrowse link
G Tlr9 toll-like receptor 9 ISO mRNA:increased expression:orbitofrontal cortex RGD PMID:34415075 RGD:597538499 NCBI chr 8:115,743,407...115,747,523
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Tnf tumor necrosis factor treatment IEP RGD PMID:32664441 RGD:597805903 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tph1 tryptophan hydroxylase 1 ISO RGD PMID:15654285 RGD:1580464 NCBI chr 1:106,293,695...106,314,628
Ensembl chr 1:97,157,409...97,178,344 		JBrowse link
G Tph2 tryptophan hydroxylase 2 ISO
IEP		 mRNA, protein:increase3d expression:dorsal raphe nucleus, median raphe nucleus
protein:decreased expression:midbrain
protein:decreased expression:hippocampus
protein:decreased expression, increased activity:raphe nuclei
associated with temporal lobe epilepsy;DNA:SNP: :rs17110747		 RGD PMID:24942188 PMID:27647531 PMID:26747301 PMID:32330588 PMID:24491795 RGD:597621679, RGD:597830173, RGD:597805906, RGD:596936412, RGD:597621680 NCBI chr 7:52,571,909...52,676,305
Ensembl chr 7:50,685,694...50,789,424 		JBrowse link
G Vip vasoactive intestinal peptide susceptibility ISO DNA:SNPs, haplotype:: (rs3823082,rs688136) (human) RGD PMID:20554694 RGD:401976551 NCBI chr 1:44,470,232...44,478,561
Ensembl chr 1:42,065,120...42,073,216 		JBrowse link
Alcohol Withdrawal Delirium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cck cholecystokinin susceptibility ISO DNA:SNP:promoter: -45C>T (human) RGD PMID:10235270 RGD:406351024 NCBI chr 8:130,031,012...130,037,702
Ensembl chr 8:121,153,500...121,160,084 		JBrowse link
G Cnr1 cannabinoid receptor 1 ISO RGD PMID:11841893 RGD:1626329 NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Ngf nerve growth factor ISO protein:increased expression:serum RGD PMID:17434673 RGD:401965399 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:16318954 RGD:5688289 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27219321 NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
Alcohol Withdrawal Seizures term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1d calcium voltage-gated channel subunit alpha1 D susceptibility IEP mRNA, protein:increased expression:inferior colliculus (rat) RGD PMID:25556199 RGD:152985539 NCBI chr16:5,233,682...5,527,549
Ensembl chr16:5,228,306...5,668,215 		JBrowse link
G Drd2 dopamine receptor D2 susceptibility ISO DNA:SNP:exon:A>G(human) RGD PMID:23238469 RGD:401959213 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Pdyn prodynorphin ISO mRNA:increased expression:brain RGD PMID:15869750 RGD:401850576 NCBI chr 3:137,354,161...137,366,503
Ensembl chr 3:116,900,992...116,913,334 		JBrowse link
G Slc29a1 solute carrier family 29 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21283641 NCBI chr 9:22,897,099...22,911,640
Ensembl chr 9:15,399,612...15,414,203 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27219321 NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
alcohol withdrawal syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avp arginine vasopressin IEP
ISO		 protein:decreased expression:suprachiasmatic nucleus
DNA:hypermethylation:promoter		 RGD PMID:11709626 PMID:24356727 RGD:596933084, RGD:596933307 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Bdnf brain-derived neurotrophic factor severity ISO
IEP		 protein:increased expression:hippocampus, prefrontal cortex RGD PMID:20553781 PMID:26659122 RGD:405849399, RGD:596936245 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 severity ISO mRNA:decreased expression:peripheral blood mononuclear cells (human) RGD PMID:20735373 RGD:401976556 NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:167,331,633...167,430,231 		JBrowse link
G Clock clock circadian regulator severity ISO mRNA:decreased expression:peripheral blood mononuclear cells (human) RGD PMID:20735373 RGD:401976556 NCBI chr14:32,262,747...32,346,872
Ensembl chr14:31,908,566...31,990,400 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 severity ISO mRNA:decreased expression:peripheral blood mononuclear cells (human) RGD PMID:20735373 RGD:401976556 NCBI chr 7:20,417,526...20,481,791
Ensembl chr 7:18,529,823...18,594,091 		JBrowse link
G Cry2 cryptochrome circadian regulator 2 ISO mRNA:decreased expression:Peripheral blood mononuclear cell (human) RGD PMID:20735373 RGD:401976556 NCBI chr 3:98,830,479...98,860,437
Ensembl chr 3:78,374,995...78,404,965 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 no_association
treatment		 ISO DNA:SNPs::CYP2C19*2 (681G>A,rs4244285), CYP2C19*3 (636G>A, rs4986893),CYP2C19*17 (-806C>T, rs12248560) (human)
DNA:SNP:promoter:CYP2C19*17 (-806C>T,rs12248560)(human)
DNA:SNP:cds:CYP2C19*2 (681G>A,rs4244285)(human)		 RGD PMID:27099220 PMID:30325732 PMID:31957548 RGD:401960863, RGD:401960882, RGD:401960880 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Dbi diazepam binding inhibitor ISO mRNA,protein:increased expression:cerebral cortex (mouse) RGD PMID:9526063 RGD:408346747 NCBI chr13:33,794,231...33,802,632
Ensembl chr13:31,206,988...31,268,693 		JBrowse link
G Drd4 dopamine receptor D4 severity ISO DNA:repeats:exon: RGD PMID:20359751 RGD:401959612 NCBI chr 1:205,825,937...205,829,124
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 severity ISO DNA:SNPs,haplotypes:multiple RGD PMID:24603855 RGD:401976481 NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,457,216...6,541,674 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit treatment IEP protein:altered expression:brain RGD PMID:26727528 PMID:31778691 RGD:405101372, RGD:405255665 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit disease_progression ISO protein:increased expression:primary motor cortex, secondary motor cortex, ventral tegmental area (mouse) RGD PMID:24355551 RGD:401851085 NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 IEP mRNA, protein:increased expression:hippocampus (rat) RGD PMID:12488536 RGD:402528882 NCBI chr10:26,876,926...26,965,523
Ensembl chr10:26,374,694...26,464,346 		JBrowse link
G Gdnf glial cell derived neurotrophic factor IDA mRNA, DNA:altered expression, hypomethylation:brain RGD PMID:31710958 RGD:405820205 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 IEP protein:increased phosphorylation:lateral habenular nucleus (rat) RGD PMID:28865912 RGD:405650672 NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Ngf nerve growth factor ISO protein:increased expression:plasma RGD PMID:8727238 RGD:401976550 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 IEP mRNA:decreased expression:hippocampus, cerebral cortex (rat) RGD PMID:20028355 RGD:10448926 NCBI chr16:27,804,416...27,814,070
Ensembl chr16:23,037,789...23,046,759 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IDA
ISO
IEP		 protein:decreased phosphorylation:prefrontal cortex
protein:decreased expression:cingulate gyrus		 RGD PMID:25732140 PMID:18801418 PMID:11961084 RGD:408345231, RGD:408345247, RGD:408345232 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 treatment IDA
IEP		 associated with Binge Drinking
protein:increased phopsphorylation, increased expression:hippocampus, prefrontal cortex		 RGD PMID:24076087 PMID:26659122 PMID:37366469 RGD:596933360, RGD:596936245, RGD:596933361 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Per1 period circadian regulator 1 severity ISO mRNA:decreased expression:peripheral blood mononuclear cells (human) RGD PMID:20735373 RGD:401976556 NCBI chr10:54,299,002...54,313,804
Ensembl chr10:53,805,535...53,814,431 		JBrowse link
G Per2 period circadian regulator 2 severity ISO mRNA:decreased expression:Peripheral blood mononuclear cell (human) RGD PMID:20735373 RGD:401976556 NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:92,007,296...92,049,459 		JBrowse link
G Pomc proopiomelanocortin IEP
ISO		 mRNA:increased expression:hypothalamus
protein:decreased expression:plasma		 RGD PMID:11981131 PMID:11704624 PMID:9406908 PMID:31117084 RGD:407424597, RGD:407550224, RGD:407550223, RGD:407431638 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Prl prolactin treatment ISO RGD PMID:3816539 RGD:401960110 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Tat tyrosine aminotransferase IEP RGD PMID:11022015 RGD:597621660 NCBI chr19:54,856,604...54,867,168
Ensembl chr19:37,947,112...37,958,031 		JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase IEP RGD PMID:11022015 RGD:597621660 NCBI chr 2:169,567,656...169,585,586
Ensembl chr 2:167,269,579...167,287,511 		JBrowse link
G Tlr2 toll-like receptor 2 ISO mRNA:increased expression:blood, monocyte RGD PMID:37058088 RGD:597538488 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
Alcohol-Induced Disorders, Nervous System term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aif1 allograft inflammatory factor 1 IEP protein:increased expression:cortex, hippocampus (rat) RGD PMID:18585922 RGD:2313030 NCBI chr20:3,651,435...3,657,341
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Cirbp cold inducible RNA binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:24223948 NCBI chr 7:10,184,515...10,189,623
Ensembl chr 7:9,424,178...9,538,818 		JBrowse link
alcohol-induced mental disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:26711020 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Ankk1 ankyrin repeat and kinase domain containing 1 ISO DNA:SNP:exon:rs1800497(human) RGD PMID:18669994 RGD:401959336 NCBI chr 8:58,676,327...58,685,012
Ensembl chr 8:49,779,862...49,788,024 		JBrowse link
G Drd2 dopamine receptor D2 ISO DNA:SNP:cds:957C>T(human) RGD PMID:18669994 RGD:401959336 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Foxo4 forkhead box O4 IEP protein:increased phosphorylation:small intestine: RGD PMID:23292333 RGD:10402360 NCBI chr  X:70,425,218...70,432,120
Ensembl chr  X:66,385,558...66,392,115 		JBrowse link
G Gsr glutathione-disulfide reductase treatment IEP RGD PMID:24972622 RGD:10401897 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Hectd4 HECT domain E3 ubiquitin protein ligase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35713687 NCBI chr12:40,800,232...40,991,584
Ensembl chr12:35,182,154...35,330,987 		JBrowse link
Alcohol-Induced Sudden Cardiac Failure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppa2 inorganic pyrophosphatase 2 ISO ClinVar Annotator: match by term: PPA2-related condition | ClinVar Annotator: match by term: Sudden cardiac failure, alcohol-induced OMIM
ClinVar		 PMID:24033266 PMID:25741868 PMID:27523597 PMID:27523598 PMID:28492532 More... NCBI chr 2:224,472,738...224,552,101
Ensembl chr 2:221,800,842...221,878,081 		JBrowse link
alcohol-related birth defects term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank3 ankyrin 3 ISO DNA:SNP:CDS:rs7917190 RGD PMID:29109170 RGD:597830079 NCBI chr20:18,601,307...19,224,790
Ensembl chr20:18,602,786...19,086,300 		JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor 10 ISO associated with cleft lip; DNA:SNP: :rs2294035, rs4876274 RGD PMID:31372216 RGD:597830081 NCBI chr16:81,349,429...81,440,439
Ensembl chr16:74,647,153...74,738,173 		JBrowse link
G Rps6ka1 ribosomal protein S6 kinase A1 ISO DNA:SNP:CDS:rs4659444 RGD PMID:29109170 RGD:597830079 NCBI chr 5:151,362,819...151,402,064
Ensembl chr 5:146,079,021...146,118,272 		JBrowse link
Alcohol-Related Disorders term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor sexual_dimorphism IEP protein:altered expression:brain
protein:altered expression:frontal cortex,hippocampus,occipital cortex
protein:altered expression:cerebral cortex		 RGD PMID:10837897 PMID:18652597 PMID:14604765 RGD:401965408, RGD:401976540, RGD:401976539 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Cartpt CART prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:22823101 NCBI chr 2:32,989,215...32,991,794
Ensembl chr 2:31,255,098...31,290,713 		JBrowse link
G Casp8 caspase 8 treatment IEP RGD PMID:30118883 RGD:13782287 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cd4 Cd4 molecule sexual_dimorphism IEP associated with Mycobacterium Infections;protein:decreased expression:spleen (rat)
protein:increases expression:spleen (rat)		 RGD PMID:9744851 PMID:8214423 RGD:407446372, RGD:407446376 NCBI chr 4:159,355,147...159,381,636
Ensembl chr 4:157,668,878...157,695,191 		JBrowse link
G Crh corticotropin releasing hormone sexual_dimorphism IEP mRNA:increased expression:fetus, thymus RGD PMID:8977428 RGD:405878076 NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit IEP protein:increased expression:liver RGD PMID:9731567 RGD:405101375 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit IEP protein:increased expression:liver RGD PMID:9731567 RGD:405101375 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Ngf nerve growth factor IEP
ISO		 protein:altered expression:brain
protein:decreased expression:entorhinal cortex
protein:increased expression:frontal cortex,cerebellar vermis
protein:increased expression:cerebral cortex
protein:increased expression:thalamus		 RGD PMID:10837897 PMID:10440485 PMID:18652597 PMID:14604765 PMID:21277941 RGD:401965408, RGD:401976542, RGD:401976540, RGD:401976539, RGD:401976494 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Ngfr nerve growth factor receptor IEP protein:decreased expression:brain
protein:altered expression:brain		 RGD PMID:15188276 PMID:15188277 RGD:401976554, RGD:401976555 NCBI chr10:81,012,077...81,030,305
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 ISO RGD PMID:16325017 RGD:408345251 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Ntf3 neurotrophin 3 IEP protein:increased expression:hippocampus,cerebellar vermis RGD PMID:18652597 RGD:401976540 NCBI chr 4:160,601,161...160,670,623
Ensembl chr 4:158,914,957...158,984,596 		JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 IEP protein:altered expression:brain
protein:decreased expression:brain		 RGD PMID:15188276 PMID:15188277 RGD:401976554, RGD:401976555 NCBI chr 2:175,534,844...175,551,664
Ensembl chr 2:173,236,963...173,253,770 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 IEP protein:altered expression:brain RGD PMID:15188276 PMID:15188277 RGD:401976554, RGD:401976555 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 IEP protein:altered expression:brain RGD PMID:15188276 PMID:15188277 RGD:401976554, RGD:401976555 NCBI chr 1:141,526,192...141,913,575
Ensembl chr 1:132,132,849...132,503,286 		JBrowse link
G Oprk1 opioid receptor, kappa 1 treatment IDA RGD PMID:20962231 RGD:401850591 NCBI chr 5:18,657,866...18,675,671
Ensembl chr 5:13,860,021...13,877,823 		JBrowse link
G Pomc proopiomelanocortin sexual_dimorphism IEP mRNA:decreased expression:fetus, thymus RGD PMID:8977428 RGD:405878076 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Tlr2 toll-like receptor 2 treatment ISO RGD PMID:26226164 RGD:597538484 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr4 toll-like receptor 4 treatment ISO RGD PMID:26226164 RGD:597538484 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tph2 tryptophan hydroxylase 2 no_association ISO DNA:SNP: :rs4570625 RGD PMID:18782386 RGD:597621690 NCBI chr 7:52,571,909...52,676,305
Ensembl chr 7:50,685,694...50,789,424 		JBrowse link
alcoholic cardiomyopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO GAD PMID:15118671 RGD:1331525 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Agt angiotensinogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:22497828 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Atg3 autophagy related 3 treatment ISO RGD PMID:29039471 RGD:407532638 NCBI chr11:69,130,948...69,159,280
Ensembl chr11:55,624,917...55,653,224 		JBrowse link
G Atg7 autophagy related 7 treatment ISO RGD PMID:29039471 RGD:407532638 NCBI chr 4:149,390,000...149,597,534
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Becn1 beclin 1 treatment ISO RGD PMID:29039471 RGD:407532638 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Nos1 nitric oxide synthase 1 IEP protein:decreased expression:skeletal muscle, membrane RGD PMID:17607508 RGD:1642138 NCBI chr12:44,276,011...44,456,371
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma IEP protein:increased expression:heart myocardium RGD PMID:18783396 RGD:2301868 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Rxra retinoid X receptor alpha IEP RGD PMID:19791468 RGD:2317465 NCBI chr 3:31,387,892...31,474,415
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Slc25a4 solute carrier family 25 member 4 IEP mRNA, protein:decreased expression:myocardium RGD PMID:21169901 RGD:9681464 NCBI chr16:52,805,521...52,809,316
Ensembl chr16:46,072,939...46,076,733 		JBrowse link
G Smad3 SMAD family member 3 IEP protein:increased expression:heart RGD PMID:19080654 RGD:597830061 NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Tnxb tenascin XB IEP protein:increased expression:heart RGD PMID:19080654 RGD:597830061
alcoholic hepatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 treatment IEP RGD PMID:27939985 RGD:15036816 NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Agt angiotensinogen ISO mRNA:decreased expression:liver RGD PMID:17258719 RGD:1601135 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Ahr aryl hydrocarbon receptor ISO protein:altered expression:hepatocyte RGD PMID:34082111 RGD:405866379 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO protein:increased expression:liver RGD PMID:28089901 RGD:407987426 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alb albumin severity ISO protein:increased expression, modification:urine RGD PMID:29369844 RGD:14694842 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G App amyloid beta precursor protein IEP protein:increased expression:liver RGD PMID:36187787 RGD:597830170 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Atg3 autophagy related 3 treatment ISO RGD PMID:36308627 RGD:407532639 NCBI chr11:69,130,948...69,159,280
Ensembl chr11:55,624,917...55,653,224 		JBrowse link
G Atg7 autophagy related 7 treatment ISO protein:increased expression:liver RGD PMID:31090940 PMID:36308627 RGD:407445926, RGD:407532639 NCBI chr 4:149,390,000...149,597,534
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Becn1 beclin 1 ISO protein:increased expression:liver RGD PMID:31090940 RGD:407445926 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 severity ISO RNA:increased expression:liver: RGD PMID:24429361 PMID:21826694 PMID:10446112 RGD:14975280, RGD:14995491, RGD:14995467 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 severity ISO RGD PMID:10446112 RGD:14995467 NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:12586603 PMID:31258651 RGD:14995304 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Col1a1 collagen type I alpha 1 chain ISO RGD PMID:1670041 RGD:5688335 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A treatment IEP RGD PMID:27939985 RGD:15036816 NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 treatment IEP RGD PMID:27939985 RGD:15036816 NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 disease_progression
severity		 ISO mRNA:increased expression:liver (mouse)
mRNA:increased expression:liver (human)		 RGD PMID:33173221 PMID:33173221 RGD:151347691, RGD:151347691 NCBI chr20:3,047,269...3,069,277
Ensembl chr20:3,044,320...3,064,468 		JBrowse link
G Fas Fas cell surface death receptor treatment IEP RGD PMID:27939985 RGD:15036816 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fgf19 fibroblast growth factor 19 treatment IEP RGD PMID:27939985 RGD:15036816 NCBI chr 1:209,485,813...209,490,267
Ensembl chr 1:200,056,644...200,060,287 		JBrowse link
G Icam1 intercellular adhesion molecule 1 severity ISO protein:increased expression:hepatocyte RGD PMID:1347281 RGD:14402038 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Il13 interleukin 13 IEP mRNA:increased expression:liver RGD PMID:16698589 RGD:1581860 NCBI chr10:38,290,926...38,293,483
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il18 interleukin 18 severity ISO associated alcoholic liver cirrhosis; protein:increased expression:plasma: RGD PMID:15566508 RGD:14696666 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Lrp1 LDL receptor related protein 1 IEP protein:decreased expression:liver RGD PMID:36187787 RGD:597830170 NCBI chr 7:65,265,639...65,346,196
Ensembl chr 7:63,380,356...63,460,910 		JBrowse link
G Mir155 microRNA 155 ameliorates IEP
ISO		 RNA:increased expression:liver RGD PMID:32317960 PMID:31090940 RGD:151347420, RGD:407445926 NCBI chr11:37,261,114...37,261,178
Ensembl chr11:23,774,654...23,774,718 		JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO protein:decreased expression:liver RGD PMID:31090940 RGD:407445926 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 treatment IEP RGD PMID:27939985 RGD:15036816 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha treatment IEP RGD PMID:27939985 RGD:15036816 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 treatment IEP RGD PMID:27939985 RGD:15036816 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 ISO protein:altered expression:hepatocyte RGD PMID:34082111 RGD:405866379 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 treatment IEP RGD PMID:27939985 RGD:15036816 NCBI chr 5:151,063,160...151,066,475
Ensembl chr 5:145,779,294...145,782,609 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 treatment IEP RGD PMID:27939985 RGD:15036816 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha treatment IEP RGD PMID:27939985 RGD:15036816 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Sell selectin L treatment ISO
IEP		 mRNA:increased expression:liver RGD PMID:10782906 PMID:9835285 RGD:597015742, RGD:597015743 NCBI chr13:78,950,100...78,969,604
Ensembl chr13:76,416,915...76,436,456 		JBrowse link
G Slc10a1 solute carrier family 10 member 1 treatment IEP RGD PMID:27939985 RGD:15036816 NCBI chr 6:106,344,319...106,357,944
Ensembl chr 6:100,613,045...100,626,670 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 IEP mRNA:decreased expression:liver RGD PMID:32317960 RGD:151347420 NCBI chr10:5,389,574...5,391,265
Ensembl chr10:4,882,560...4,884,383 		JBrowse link
G Sqstm1 sequestosome 1 treatment ISO protein:increased expression:liver RGD PMID:31090940 PMID:36308627 RGD:407445926, RGD:407532639 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 treatment IEP RGD PMID:27939985 RGD:15036816 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Sts steroid sulfatase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26220752 NCBI chr  X:46,102,524...46,110,868
Ensembl chr  X:42,225,372...42,233,402 		JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26220752 NCBI chr14:20,700,444...20,718,719
Ensembl chr14:20,422,324...20,439,275 		JBrowse link
G Tnf tumor necrosis factor treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:12586603 PMID:27939985 RGD:15036816 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Alcoholic Intoxication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arc activity-regulated cytoskeleton-associated protein disease_progression ISO mRNA:altered expression:brain (mouse) RGD PMID:26708208 RGD:401853772 NCBI chr 7:108,444,959...108,448,413
Ensembl chr 7:106,555,785...106,559,378 		JBrowse link
G Bdnf brain-derived neurotrophic factor ISO mRNA,protein:decreased expression:cerebellum RGD PMID:19861148 RGD:401965398 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Drd2 dopamine receptor D2 treatment IDA RGD PMID:28300818 RGD:13506954 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit IEP protein:altered expression:brain
mRNA:decreased expression:adrenal gland		 RGD PMID:26727528 PMID:12351928 RGD:405101372, RGD:405255666 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Gdnf glial cell derived neurotrophic factor ISO mRNA:decreased expression:basal nucleus RGD PMID:24061482 RGD:405850213 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Ifng interferon gamma treatment ISO RGD PMID:9514301 RGD:10755766 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Ngf nerve growth factor ISO mRNA,protein:increased expression:cerebellum
protein:increased expression:plasma		 RGD PMID:19861148 PMID:18639986 RGD:401965398, RGD:401965411 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Nps neuropeptide S IDA RGD PMID:19860802 RGD:9831199 NCBI chr 1:199,505,772...199,510,915
Ensembl chr 1:190,077,040...190,080,821 		JBrowse link
G Npsr1 neuropeptide S receptor 1 IEP mRNA:increased expression:brain RGD PMID:19860802 RGD:9831199 NCBI chr 8:30,882,830...31,107,425
Ensembl chr 8:22,606,946...22,831,558 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 sexual_dimorphism ISO DNA:SNP: :rs244465 RGD PMID:20731635 RGD:408345194 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 ISO mRNA,protein:increased expression:cerebellum RGD PMID:19861148 RGD:401965398 NCBI chr 2:175,534,844...175,551,664
Ensembl chr 2:173,236,963...173,253,770 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 ISO mRNA:increased expression:basal nucleus, cerebral cortex RGD PMID:24061482 RGD:405850213 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Per2 period circadian regulator 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15608650 NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:92,007,296...92,049,459 		JBrowse link
alcoholic liver cirrhosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member susceptibility ISO DNA:missense mutation:cds:p.E504K (human)
DNA:missense mutation:cds: (rs671) (human)
associated with alcohol dependence;DNA:missense mutation:exon 12:p.E487K (human)		 RGD PMID:29779728 PMID:23550892 PMID:11051375 RGD:14696777, RGD:15042864, RGD:15042858 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Bcl2 BCL2, apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:23274713 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G C3 complement C3 ISO RGD PMID:9176087 RGD:408418722 NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Cat catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23274713 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase ISO protein:decreased expression:brain RGD PMID:16205370 RGD:6483345 NCBI chr10:86,011,504...86,018,063
Ensembl chr10:85,511,160...85,517,720 		JBrowse link
G Col3a1 collagen type III alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:23274713 NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Crp C-reactive protein severity ISO RGD PMID:22441510 RGD:6482305 NCBI chr13:87,694,062...87,695,978
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20843640 PMID:29404441 RGD:14700873 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 severity ISO mRNA:increased expression:liver (human) RGD PMID:33173221 RGD:151347691 NCBI chr20:3,047,269...3,069,277
Ensembl chr20:3,044,320...3,064,468 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 disease_progression
ameliorates		 IEP
IMP		 RGD PMID:21199726 PMID:23409069 RGD:150429766, RGD:150517731 NCBI chr13:84,726,412...84,851,032
Ensembl chr13:82,195,463...82,317,363 		JBrowse link
G Fabp2 fatty acid binding protein 2 onset ISO DNA:polymorphism:CDS:amino acid A54T, homozygosity of the T allele associated with later onset RGD PMID:16289894 PMID:16289894 RGD:1578455, RGD:1578455 NCBI chr 2:213,724,629...213,728,686
Ensembl chr 2:211,040,032...211,044,089 		JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 susceptibility ISO DNA:SNP:intron 8:84435G>A (human) RGD PMID:19428381 RGD:402463950 NCBI chr10:26,876,926...26,965,523
Ensembl chr10:26,374,694...26,464,346 		JBrowse link
G Il18bp interleukin 18 binding protein ISO protein:increased expression:plasma: RGD PMID:15566508 RGD:14696666 NCBI chr 1:165,784,916...165,787,990
Ensembl chr 1:156,372,883...156,374,963 		JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:23274713 PMID:21236309 RGD:597538491 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Jak2 Janus kinase 2 ISO mRNA, protein:increased expression, increased tyrosine phosphorylation:liver RGD PMID:24619965 RGD:10403061 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Lep leptin IDA DNA:hypomethylation:promoter (human) RGD PMID:29912265 RGD:21201248 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Mboat7 membrane bound O-acyltransferase domain containing 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26482880 NCBI chr 1:74,440,618...74,454,896
Ensembl chr 1:65,525,213...65,539,538 		JBrowse link
G Mir122 microRNA 122 ISO miRNA:decreased expression:liver RGD PMID:28987423 RGD:14401600 NCBI chr18:61,028,817...61,028,901 JBrowse link
G Mir141 microRNA 141 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 4:159,209,525...159,209,618
Ensembl chr 4:157,523,239...157,523,332 		JBrowse link
G Mir17 microRNA 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr15:98,587,848...98,587,931
Ensembl chr15:92,180,629...92,180,712 		JBrowse link
G Mir193b microRNA 193b ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr10:1,824,944...1,825,026
Ensembl chr10:1,317,742...1,317,824 		JBrowse link
G Mir423 microRNA 423 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr10:62,412,272...62,412,350
Ensembl chr10:61,914,133...61,914,226 		JBrowse link
G Mir484 microRNA 484 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr10:1,394,905...1,394,981
Ensembl chr10:887,684...887,760 		JBrowse link
G Mir532 microRNA 532 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr  X:17,919,185...17,919,263
Ensembl chr  X:15,247,315...15,247,393 		JBrowse link
G Mir93 microRNA 93 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr12:22,156,844...22,156,930
Ensembl chr12:17,043,135...17,043,221 		JBrowse link
G Mmp13 matrix metallopeptidase 13 IEP RGD PMID:16286264 RGD:10043176 NCBI chr 8:12,782,829...12,793,108
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23274713 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19731237 PMID:23274713 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase susceptibility ISO DNA:SNP: :677C>T(human) RGD PMID:25987440 RGD:14696749 NCBI chr 5:163,748,346...163,768,141
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 ISO RGD PMID:24497272 RGD:10448995 NCBI chr10:84,224,599...84,231,812
Ensembl chr10:83,728,318...83,735,705 		JBrowse link
G Plau plasminogen activator, urokinase IDA RGD PMID:19615318 RGD:7241800 NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19946271 PMID:26482880 NCBI chr 7:117,173,485...117,194,065
Ensembl chr 7:115,293,538...115,314,077 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:23274713 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Serpine1 serpin family E member 1 susceptibility ISO DNA:polymorphism:promoter: RGD PMID:25987440 RGD:14696749 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Serpinf1 serpin family F member 1 ISO protein:increased expression:serum (human) RGD PMID:27748324 RGD:27226704 NCBI chr10:60,748,504...60,760,898
Ensembl chr10:60,249,708...60,262,646 		JBrowse link
G Smad3 SMAD family member 3 treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:23274713 PMID:18180699 RGD:597830076 NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Sod2 superoxide dismutase 2 susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:SNP: : 47T>C(human)		 CTD
RGD		 PMID:19731237 PMID:26873981 RGD:11060603 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Tg thyroglobulin ISO RGD PMID:6883738 RGD:401976502 NCBI chr 7:100,307,349...100,492,246
Ensembl chr 7:98,418,293...98,603,210 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23274713 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23274713 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tlr2 toll-like receptor 2 ISO protein:increased expression:blood, neutrophil RGD PMID:18433921 RGD:5130706 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr4 toll-like receptor 4 treatment ISO RGD PMID:18433921 RGD:5130706 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr9 toll-like receptor 9 ISO protein:increased expression:blood, neutrophil RGD PMID:18433921 RGD:5130706 NCBI chr 8:115,743,407...115,747,523
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Tm6sf2 transmembrane 6 superfamily member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26482880 NCBI chr16:19,378,148...19,385,360
Ensembl chr16:19,344,222...19,351,431 		JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23274713 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Alcoholic Liver Diseases term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme severity
treatment		 ISO protein:increased activity:serum (human) RGD PMID:3028446 PMID:28691216 RGD:19165343, RGD:40400719 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Adipor2 adiponectin receptor 2 treatment IEP RGD PMID:24797033 RGD:25824940 NCBI chr 4:154,195,440...154,261,141
Ensembl chr 4:152,524,623...152,559,355 		JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO mRNA, protein:increased expression:serum RGD PMID:36502724 RGD:597538595 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Ahr aryl hydrocarbon receptor exacerbates
ameliorates		 ISO RGD PMID:34454169 PMID:36871955 RGD:405866377, RGD:405866378 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 treatment ISO RGD PMID:35926779 RGD:408345226 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member susceptibility
severity		 ISO DNA:missense mutation:cds, exon 12:p.E487K (human)
DNA:polymorphism:exon 12: (human)
DNA:deletion:cds: (mouse)		 RGD PMID:1916152 PMID:12198368 PMID:26173414 PMID:3189338 RGD:14696699, RGD:14981580, RGD:11076022, RGD:14696790 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Angpt2 angiopoietin 2 severity ISO RGD PMID:24959006 RGD:15014784 NCBI chr16:77,790,760...77,841,241
Ensembl chr16:71,088,364...71,138,804 		JBrowse link
G Atg7 autophagy related 7 ISO protein:increased expression:liver RGD PMID:31090940 RGD:407445926 NCBI chr 4:149,390,000...149,597,534
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Becn1 beclin 1 ISO protein:increased expression:liver RGD PMID:31090940 RGD:407445926 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase IEP protein:increased expression:cytosol RGD PMID:25684186 RGD:408418736 NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
G C6 complement C6 resistance IAGP RGD PMID:15351314 RGD:1600673 NCBI chr 2:55,573,596...55,648,857
Ensembl chr 2:53,851,985...53,921,275 		JBrowse link
G Car3 carbonic anhydrase 3 IEP protein:decreased expression:cytosol RGD PMID:25684186 RGD:408418736 NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Cat catalase treatment IEP RGD PMID:8370342 PMID:28898587 RGD:405255646, RGD:405255658 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cav1 caveolin 1 treatment IEP RGD PMID:23764359 RGD:8662277 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cd27 CD27 molecule IEP RGD PMID:16698589 RGD:1581860 NCBI chr 4:159,716,932...159,721,823
Ensembl chr 4:158,030,703...158,035,592 		JBrowse link
G Cd59b CD59b molecule IEP protein:decreased expression:liver RGD PMID:12483994 RGD:1600486 NCBI chr 3:110,914,008...110,932,489
Ensembl chr 3:90,459,162...90,478,847 		JBrowse link
G Cldn1 claudin 1 treatment IEP RGD PMID:31116255 RGD:407424600 NCBI chr11:87,926,376...87,941,533
Ensembl chr11:74,421,569...74,436,724 		JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 IEP protein:increased expression:cytosol RGD PMID:25684186 RGD:408418736 NCBI chr 9:76,063,863...76,186,739
Ensembl chr 9:68,614,153...68,737,033 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 susceptibility ISO DNA:SNP::-318 T>C(rs5742909)(human) RGD PMID:15208156 RGD:14398728 NCBI chr 9:69,812,859...69,819,959
Ensembl chr 9:62,319,312...62,324,963 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 IEP mRNA:increased expression:liver RGD PMID:10498645 RGD:5135271 NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 IEP mRNA:increased expression:liver RGD PMID:10498645 RGD:5135271 NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 IEP mRNA:increased expression:liver RGD PMID:10498645 RGD:5135271 NCBI chr14:17,594,959...17,596,417
Ensembl chr14:17,310,426...17,313,093 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 treatment ISO
IEP		 RGD PMID:29401608 PMID:9927612 PMID:30192013 PMID:25592162 PMID:29902864 RGD:14700887, RGD:405650696, RGD:14700906, RGD:14700894, RGD:14700893 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 ISO RGD PMID:9927612 RGD:405650696 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Egfr epidermal growth factor receptor ISO RGD PMID:30502657 RGD:38599215 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha IDA RGD PMID:21059295 RGD:10395351 NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Fas Fas cell surface death receptor ISO protein:increased expression:lymphocyte: RGD PMID:26429926 RGD:14700711 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 ameliorates ISO mRNA,protein:incrased expression:liver (human) RGD PMID:33710653 PMID:33710653 RGD:401976495, RGD:401976495 NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,457,216...6,541,674 		JBrowse link
G Gdnf glial cell derived neurotrophic factor ISO protein:increased expression:serum
mRNA,protein:increased expression:liver		 RGD PMID:35338490 PMID:35338490 RGD:405849393, RGD:405849393 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 ISO RGD PMID:15932176 PMID:26937962 RGD:14700973, RGD:11060494 NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 ISO RGD PMID:15932176 PMID:26937962 RGD:14700973, RGD:11060494 NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G Hfe homeostatic iron regulator IEP mRNA:increased expression:liver, Kupffer cell (rat) RGD PMID:18599584 RGD:8694397 NCBI chr17:41,841,302...41,849,359
Ensembl chr17:41,413,451...41,421,502 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IEP mRNA:increased expression:liver (rat) RGD PMID:17085342 RGD:9068897 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Igf2 insulin-like growth factor 2 IEP mRNA:increased expression:liver RGD PMID:18505416 RGD:5510002 NCBI chr 1:207,243,873...207,261,263
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Il1b interleukin 1 beta IEP protein:increased expression:serum (rat) RGD PMID:23009062 RGD:7204488 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 treatment IEP RGD PMID:31116255 RGD:407424600 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 ISO mRNA:decreased expression:liver (human) RGD PMID:22459801 RGD:6892954 NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Lpl lipoprotein lipase treatment IEP RGD PMID:28442378 RGD:13794376 NCBI chr16:25,596,205...25,621,928
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
G Mif macrophage migration inhibitory factor IEP protein:increased expression:liver RGD PMID:11798463 RGD:1642007 NCBI chr20:12,767,138...12,791,222
Ensembl chr20:12,790,902...12,799,504
Ensembl chr 4:12,790,902...12,799,504 		JBrowse link
G Mir122 microRNA 122 ISO miRNA:decreased expression:hepatocyte RGD PMID:28987423 RGD:14401600 NCBI chr18:61,028,817...61,028,901 JBrowse link
G Mir155 microRNA 155 ameliorates ISO RNA:increased expression:liver RGD PMID:28492308 PMID:31090940 PMID:31090940 RGD:25314298, RGD:407445926, RGD:407445926 NCBI chr11:37,261,114...37,261,178
Ensembl chr11:23,774,654...23,774,718 		JBrowse link
G Mir223 microRNA 223 severity ISO RGD PMID:27679493 RGD:21408575 NCBI chr  X:65,151,383...65,151,492
Ensembl chr  X:61,141,887...61,141,996 		JBrowse link
G Mmp9 matrix metallopeptidase 9 IEP protein:increased expression:liver RGD PMID:17374579 RGD:1642042 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO protein:decreased expression:liver RGD PMID:31090940 PMID:31090940 RGD:407445926, RGD:407445926 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor disease_progression
severity		 ISO mRNA:increased expression:liver RGD PMID:26576483 PMID:26576483 RGD:14695016, RGD:14695016 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nedd8 NEDD8 ubiquitin like modifier ISO RGD PMID:12533840 RGD:1549458 NCBI chr15:33,123,505...33,135,522
Ensembl chr15:29,153,556...29,166,160 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 treatment
severity		 ISO DNA:SNP:promoter:rs35652124(human) RGD PMID:31906014 PMID:31340446 RGD:21201307, RGD:21201311 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 ameliorates ISO RGD PMID:34082111 RGD:405866379 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Otc ornithine transcarbamylase IEP protein:increased expression:serum (rat) RGD PMID:19101528 RGD:4144059 NCBI chr  X:15,126,358...15,202,473
Ensembl chr  X:12,453,834...12,566,918 		JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO protein:increased expression:serum RGD PMID:22098627 RGD:6484116 NCBI chr 1:89,181,363...89,196,308
Ensembl chr 1:80,050,324...80,068,595 		JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19946271 NCBI chr 7:117,173,485...117,194,065
Ensembl chr 7:115,293,538...115,314,077 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha severity ISO DNA:knockout::increased severity in knockouts (mouse) RGD PMID:15382117 RGD:5683636 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta ISO CTD Direct Evidence: marker/mechanism CTD PMID:27765815 NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Psmd14 proteasome 26S subunit, non-ATPase 14 IEP protein:decreased expression:liver, cytosolic proteasome complex (rat) RGD PMID:19609968 RGD:9480236 NCBI chr 3:66,662,933...66,755,666
Ensembl chr 3:46,254,330...46,347,076 		JBrowse link
G Rbp4 retinol binding protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762690 NCBI chr 1:245,306,349...245,313,551
Ensembl chr 1:235,893,917...235,901,399 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO protein:increased phosphorylation:liver RGD PMID:35338490 RGD:405849393 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Slc39a13 solute carrier family 39 member 13 IEP protein:increased expression:liver, endoplasmic reticulum (rat) RGD PMID:25767260 RGD:11553884 NCBI chr 3:97,495,229...97,504,279
Ensembl chr 3:77,037,565...77,049,226 		JBrowse link
G Sod1 superoxide dismutase 1 treatment ISO human gene in a rat model RGD PMID:11266387 RGD:9587792 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 treatment ISO RGD PMID:32236798 RGD:27095880 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18703563 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Sqstm1 sequestosome 1 ISO protein:increased expression:liver RGD PMID:31090940 PMID:31090940 RGD:407445926, RGD:407445926 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Tbxas1 thromboxane A synthase 1 IEP mRNA,protein:increased expression:liver, Kupffer cell: RGD PMID:9262373 RGD:11059607 NCBI chr 4:68,631,841...68,803,959
Ensembl chr 4:67,665,007...67,837,096 		JBrowse link
G Tert telomerase reverse transcriptase ISO mRNA,protein,activity:increased expression, increased activity:kupffer cell: RGD PMID:26725521 RGD:11574970 NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tlr2 toll-like receptor 2 treatment ISO mRNA:increased expression:liver RGD PMID:16628628 PMID:30353422 RGD:597538497, RGD:597538498 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr3 toll-like receptor 3 treatment ISO RGD PMID:23023014 PMID:30870678 RGD:21079426, RGD:21079436 NCBI chr16:53,554,916...53,572,321
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr4 toll-like receptor 4 ISO mRNA:increased expression:liver RGD PMID:16628628 RGD:597538497 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor treatment IMP
IEP		 mRNA:increased expression:liver (rat) RGD PMID:9397994 PMID:31116255 PMID:7556590 PMID:15670576 RGD:14398736, RGD:407424600, RGD:14995472, RGD:14995456 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 IEP protein:decreased expression:liver, cytosolic proteasome complex RGD PMID:19609968 RGD:9480236 NCBI chr13:58,070,947...58,106,825
Ensembl chr13:55,520,729...55,556,502 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO protein:increased expression:plasma RGD PMID:24959006 RGD:15014784 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
alcoholic neuropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Igf1 insulin-like growth factor 1 IEP RGD PMID:23016131 RGD:10402569 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor IEP RGD PMID:23016131 RGD:10402569 NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Igf2 insulin-like growth factor 2 IEP RGD PMID:23016131 RGD:10402569 NCBI chr 1:207,243,873...207,261,263
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 treatment IMP RGD PMID:18093169 RGD:408345248 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
alcoholic pancreatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car2 carbonic anhydrase 2 ISO RGD PMID:15831920 RGD:408425973 NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:86,741,626...86,756,818 		JBrowse link
G Cck cholecystokinin disease_progression ISO protein:decreased expression:blood plasma (human) RGD PMID:11185710 RGD:407419866 NCBI chr 8:130,031,012...130,037,702
Ensembl chr 8:121,153,500...121,160,084 		JBrowse link
G Cftr CF transmembrane conductance regulator ISO DNA:missense mutations: :p.L1156F, Q1352H (human) RGD PMID:26089335 RGD:11566036 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Pthlh parathyroid hormone-like hormone ISO CTD Direct Evidence: marker/mechanism CTD PMID:22280800 NCBI chr 4:181,919,400...181,930,454
Ensembl chr 4:180,188,792...180,199,847 		JBrowse link
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C ISO DNA:polymorphisms: :p.N129K, p.R131K, p.W208R (human) RGD PMID:12806614 RGD:2317503 NCBI chr 9:96,187,382...96,256,264
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
alcoholic psychosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr2a 5-hydroxytryptamine receptor 2A ISO DNA:SNP:promoter:-1438G>A RGD PMID:11842624 RGD:401900738 NCBI chr15:56,360,647...56,428,703
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
amphetamine abuse term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16470869 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr10:38,940,668...38,999,515
Ensembl chr10:38,440,080...38,498,757 		JBrowse link
G Adora2a adenosine A2a receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20799992 NCBI chr20:13,315,270...13,332,802
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Ak5 adenylate kinase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 2:244,057,240...244,241,372
Ensembl chr 2:241,397,297...241,581,458 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 no_association
susceptibility		 ISO CTD Direct Evidence: marker/mechanism
DNA:SNPs:introns: (rs2494743, 2498794)
DNA:SNP:intron: (rs3730358)		 CTD
RGD		 PMID:15982448 PMID:31654273 PMID:15982448 RGD:407419880, RGD:407419878 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Aoah acyloxyacyl hydrolase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr17:48,503,812...48,745,161
Ensembl chr17:43,809,638...44,049,148 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein disease_progression ISO mRNA:increased expression:brain (mouse) RGD PMID:25959066 RGD:401938592 NCBI chr 7:108,444,959...108,448,413
Ensembl chr 7:106,555,785...106,559,378 		JBrowse link
G Arrb2 arrestin, beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17233643 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Astn2 astrotactin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 5:83,772,988...84,759,439
Ensembl chr 5:78,758,142...79,748,273 		JBrowse link
G Bdnf brain-derived neurotrophic factor ISO
IEP		 CTD Direct Evidence: marker/mechanism
protein:increased expression:frontal cortex, striatum
protein:increased expression:nucleus accumbens, ventral tegmental area
mRNA:increased expression:nucleus accumbens, dorsal striatum
protein:decreased expression:hippocampus		 CTD
RGD		 PMID:20736000 PMID:31693929 PMID:37904065 PMID:33961872 PMID:24407463 RGD:597015747, RGD:596938173, RGD:596936246, RGD:401976437 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Cartpt CART prepropeptide IEP mRNA:increased expression:striatum RGD PMID:28827541 RGD:407984842 NCBI chr 2:32,989,215...32,991,794
Ensembl chr 2:31,255,098...31,290,713 		JBrowse link
G Cat catalase treatment IEP RGD PMID:24445072 RGD:405255657 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cchcr1 coiled-coil alpha-helical rod protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr20:3,210,383...3,223,187
Ensembl chr20:3,205,676...3,218,308 		JBrowse link
G Cd4 Cd4 molecule IEP protein:decreased expression:spleen (rat) RGD PMID:25678251 RGD:407446373 NCBI chr 4:159,355,147...159,381,636
Ensembl chr 4:157,668,878...157,695,191 		JBrowse link
G Cd55 CD55 molecule (Cromer blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr13:44,409,574...44,438,913
Ensembl chr13:41,857,395...41,885,831 		JBrowse link
G Cd8a CD8 subunit alpha IEP protein:increased expression:spleen (rat) RGD PMID:25678251 RGD:407446373 NCBI chr 4:104,924,116...104,928,353
Ensembl chr 4:103,365,804...103,370,040 		JBrowse link
G Cdh13 cadherin 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr19:63,258,251...64,296,122
Ensembl chr19:46,349,430...47,387,459 		JBrowse link
G Cdk5 cyclin-dependent kinase 5 ISO protein:increased expression:ventral tegmental area, nucleus accumbens (mouse) RGD PMID:28782589 RGD:401900303 NCBI chr 4:11,647,098...11,651,606
Ensembl chr 4:10,754,687...10,760,112 		JBrowse link
G Cfh complement factor H ISO
IEP		 protein:increased expression:serum:
protein:increased expression:serum, hippocampus:		 RGD PMID:22871478 PMID:22871478 RGD:7364944, RGD:7364944 NCBI chr13:54,063,079...54,164,523
Ensembl chr13:51,511,828...51,613,838 		JBrowse link
G Col28a1 collagen type XXVIII alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 4:37,036,303...37,189,435
Ensembl chr 4:36,069,970...36,223,220 		JBrowse link
G Comt catechol-O-methyltransferase susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:SNP:cd: p.V158M (human)
DNA:SNPs,haplotypes:exon,3'utr: (rs4680, rs165599) (human)
ClinVar Annotator: match by term: methamphetamine use disorder		 CTD
ClinVar
RGD		 PMID:15274053 PMID:25741868 PMID:33544778 PMID:21934638 PMID:17187009 More... RGD:401959602, RGD:401940147, RGD:401940150, RGD:401940124 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 treatment ISO
IEP		 protein:increases activity:ventral tegmental area, nucleus accumbens (mouse)
mRNA:decreased expression:nucleus accumbens
protein:increased expression, increased phosphorylation:nucleus accumbens, ventral tegmental area		 RGD PMID:28782589 PMID:33961872 PMID:31900897 RGD:401900303, RGD:596936246, RGD:401938636 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Csmd1 CUB and Sushi multiple domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr16:78,920,549...80,520,710
Ensembl chr16:72,218,503...73,817,614 		JBrowse link
G Cubn cubilin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr17:81,293,619...81,501,694
Ensembl chr17:76,385,060...76,593,231 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18280655 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 7:72,692,364...72,706,983
Ensembl chr 7:70,807,581...70,822,078 		JBrowse link
G Drd1 dopamine receptor D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18363855 PMID:19444617 NCBI chr17:10,545,488...10,550,029
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18363855 PMID:18555060 PMID:19940168 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19940168 NCBI chr11:70,385,586...70,437,793
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Drd4 dopamine receptor D4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15274053 NCBI chr 1:205,825,937...205,829,124
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Ephx1 epoxide hydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19598248 NCBI chr13:95,246,079...95,275,852
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr15:16,365,401...17,872,901
Ensembl chr15:13,934,995...15,442,340 		JBrowse link
G Fkbp15 FKBP prolyl isomerase family member 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 5:80,766,356...80,830,622
Ensembl chr 5:75,750,787...75,814,990 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit ISO
IEP		 CTD Direct Evidence: marker/mechanism
protein:increased expression:nucleus accumbens,striatum
mRNA:increased expression:nucleus accumbens		 CTD
RGD		 PMID:19689456 PMID:18834549 PMID:24183790 RGD:405255667, RGD:405100720 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit ISO
IEP		 protein:increased expression:ventral tegmental area, nucleus accumbens (mouse)
associated with stress related disorder;protein:increased expression:brain (rat)		 RGD PMID:28782589 PMID:27672362 PMID:31373119 RGD:401900303, RGD:401901183, RGD:401900735 NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 susceptibility ISO DNA:SNPs, halotypes:intron (rs2076483,rs29221,rs715044) (human) RGD PMID:30143926 RGD:401940101 NCBI chr20:1,469,779...1,499,352
Ensembl chr20:1,464,534...1,493,994 		JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 sexual_dimorphism ISO CTD Direct Evidence: marker/mechanism
DNA:missense mutation:exon 8:p.K289M (rs4480617) (human)		 CTD
RGD		 PMID:15772696 PMID:14569258 RGD:402528887 NCBI chr10:26,876,926...26,965,523
Ensembl chr10:26,374,694...26,464,346 		JBrowse link
G Gad1 glutamate decarboxylase 1 susceptibility ISO DNA:haplotype: :rs769404���rs701492(human) RGD PMID:27967329 RGD:401900122 NCBI chr 3:75,777,260...75,818,099
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gad2 glutamate decarboxylase 2 susceptibility ISO DNA:SNP: :rs2236418(human) RGD PMID:27967329 RGD:401900122 NCBI chr17:89,671,718...89,734,246
Ensembl chr17:84,763,628...84,826,155 		JBrowse link
G Gdnf glial cell derived neurotrophic factor treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism
protein:increased expression:nucleus accumbens, ventral tegmental area		 CTD
RGD		 PMID:17356005 PMID:37904065 PMID:23432945 RGD:596938173, RGD:405850210 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 IEP methamphetamine abuse;protein:increased expression:hippocampal formation, striatum, prefrontal cortex (rat) RGD PMID:37778205 RGD:405100237 NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 IMP RGD PMID:16311338 RGD:596933067 NCBI chr 2:168,247,490...168,367,616
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Grm2 glutamate metabotropic receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20211215 NCBI chr 8:116,158,810...116,171,857
Ensembl chr 8:107,280,099...107,293,146 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19254865 NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15729709 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18186040 PMID:19254865 NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G Hdac8 histone deacetylase 8 IEP mRNA:decreased expression:striatum (rat) RGD PMID:25452209 RGD:9681719 NCBI chr  X:71,425,240...71,632,865
Ensembl chr  X:67,385,289...67,592,923 		JBrowse link
G Hs3st4 heparan sulfate-glucosamine 3-sulfotransferase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 1:187,970,127...188,375,869
Ensembl chr 1:178,539,093...178,944,107 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B ISO CTD Direct Evidence: therapeutic CTD PMID:10780831 NCBI chr 8:91,395,405...91,414,815
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19689456 NCBI chr 8:58,138,514...58,150,960
Ensembl chr 8:49,242,020...49,254,389 		JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20705401 NCBI chr 5:156,579,901...156,595,147
Ensembl chr 5:151,296,662...151,311,912 		JBrowse link
G Large1 LARGE xylosyl- and glucuronyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr19:11,609,004...12,057,174
Ensembl chr19:11,603,129...12,048,930 		JBrowse link
G Lingo2 leucine rich repeat and Ig domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 5:55,166,250...56,488,672
Ensembl chr 5:50,367,101...50,516,956 		JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 8:72,520,616...72,748,395
Ensembl chr 8:63,625,221...63,851,983 		JBrowse link
G Mb myoglobin ISO RGD PMID:12935649 RGD:458925289 NCBI chr 7:110,640,511...110,647,742
Ensembl chr 7:108,759,904...108,767,383 		JBrowse link
G Mtarc1 mitochondrial amidoxime reducing component 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr13:98,854,235...98,894,208
Ensembl chr13:96,339,757...96,397,796 		JBrowse link
G Mtarc2 mitochondrial amidoxime reducing component 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr13:98,894,347...98,928,754 JBrowse link
G Myo5b myosin Vb ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr18:70,313,717...70,613,918
Ensembl chr18:68,038,759...68,338,745 		JBrowse link
G Nos1 nitric oxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15542708 NCBI chr12:44,276,011...44,456,371
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 ISO CTD Direct Evidence: marker/mechanism
DNA:SNP:intron: (rs7687423) (human)		 CTD
RGD		 PMID:19566775 PMID:19566775 RGD:402463941 NCBI chr16:27,804,416...27,814,070
Ensembl chr16:23,037,789...23,046,759 		JBrowse link
G Nrg1 neuregulin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr16:65,954,084...67,007,484
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 IEP
ISO		 mRNA:increased expression:nucleus accumbens
protein:increased expression:frontal cortex, striatum
protein:altered expression:nucleus accumbens, ventral tegmental area		 RGD PMID:33961872 PMID:31693929 PMID:37904065 PMID:34273388 RGD:596936246, RGD:597015747, RGD:596938173, RGD:596938171 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Oprm1 opioid receptor, mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16402083 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide IEP mRNA:increased expression:nucleus accumbens RGD PMID:28827541 RGD:407984842 NCBI chr 3:138,235,754...138,236,594
Ensembl chr 3:117,782,650...117,783,490 		JBrowse link
G Pcolce2 procollagen C-endopeptidase enhancer 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 8:105,073,086...105,130,725
Ensembl chr 8:96,193,461...96,251,114 		JBrowse link
G Pde4b phosphodiesterase 4B ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 5:122,028,956...122,598,267
Ensembl chr 5:116,799,971...117,367,696 		JBrowse link
G Pde4d phosphodiesterase 4D ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 2:41,748,337...43,262,567
Ensembl chr 2:40,019,933...41,525,884 		JBrowse link
G Pde6c phosphodiesterase 6C ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 1:245,322,015...245,377,874
Ensembl chr 1:235,909,775...235,965,315 		JBrowse link
G Pdyn prodynorphin ISO
IEP		 CTD Direct Evidence: marker/mechanism
mRNA:increased expression:nucleus acccumbens
mRNA:increased expression:nucleus accumbens
mRNA:increased expression:central amygdaloid nucleus
mRNA:altered expression:brain
DNA:repeat:promoter:rs35286251 (human)		 CTD
RGD		 PMID:16529859 PMID:27989838 PMID:22390687 PMID:12523490 PMID:16289352 More... RGD:401851910, RGD:401851043, RGD:401850585, RGD:401850564, RGD:401850552 NCBI chr 3:137,354,161...137,366,503
Ensembl chr 3:116,900,992...116,913,334 		JBrowse link
G Pick1 protein interacting with PRKCA 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17606663 NCBI chr 7:112,676,890...112,697,275
Ensembl chr 7:110,797,117...110,816,848 		JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: marker/mechanism CTD PMID:15659235 NCBI chr16:75,943,061...76,022,037
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr20:3,227,836...3,232,598
Ensembl chr20:3,223,129...3,227,891 		JBrowse link
G Prdm2 PR/SET domain 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 5:160,704,396...160,815,184
Ensembl chr 5:155,422,134...155,531,825 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha treatment IEP protein:increased expression, increased phosphorylation:nucleus accumbens, ventral tegmental area RGD PMID:31900897 RGD:401938636 NCBI chr19:41,059,843...41,083,189
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 1:237,818,950...239,052,184
Ensembl chr 1:228,408,947...229,639,080 		JBrowse link
G Prokr2 prokineticin receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20576534 NCBI chr 3:140,077,629...140,092,327
Ensembl chr 3:119,627,601...119,635,718 		JBrowse link
G Psd3 pleckstrin and Sec7 domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr16:26,238,595...26,802,535
Ensembl chr16:21,465,639...22,034,547 		JBrowse link
G Raly RALY heterogeneous nuclear ribonucleoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 3:163,766,183...163,830,726
Ensembl chr 3:143,306,300...143,370,539 		JBrowse link
G Rapgef5 Rap guanine nucleotide exchange factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 6:144,588,162...144,822,908
Ensembl chr 6:138,437,991...138,679,936 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19689456 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rgs17 regulator of G-protein signaling 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 1:44,627,583...44,729,957
Ensembl chr 1:42,227,070...42,324,609 		JBrowse link
G Serpina5 serpin family A member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 6:128,774,006...128,793,187
Ensembl chr 6:123,023,306...123,028,407 		JBrowse link
G Sgcz sarcoglycan zeta ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr16:60,363,718...61,444,256
Ensembl chr16:53,660,502...54,735,193 		JBrowse link
G Sh3rf3 SH3 domain containing ring finger 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr20:27,306,937...27,642,315
Ensembl chr20:26,765,015...27,099,257 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12931138 NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19689456 NCBI chr10:62,322,688...62,357,060
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Slc6a9 solute carrier family 6 member 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17582620 NCBI chr 5:136,660,022...136,694,173
Ensembl chr 5:131,374,542...131,408,728 		JBrowse link
G Smyd3 SET and MYND domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr13:93,241,274...93,798,221
Ensembl chr13:90,709,270...91,266,253 		JBrowse link
G Snca synuclein alpha treatment IMP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:15542733 PMID:32278788 PMID:20551914 RGD:13506280 NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Tph2 tryptophan hydroxylase 2 ISO protein:decreased expression:hippocampus RGD PMID:26747301 RGD:597805906 NCBI chr 7:52,571,909...52,676,305
Ensembl chr 7:50,685,694...50,789,424 		JBrowse link
G Trpm3 transient receptor potential cation channel, subfamily M, member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 1:229,099,741...229,984,172
Ensembl chr 1:219,672,892...220,560,717 		JBrowse link
G Usp48 ubiquitin specific peptidase 48 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 5:155,083,520...155,151,208
Ensembl chr 5:149,800,179...149,867,719 		JBrowse link
G Zfp385d zinc finger protein 385D ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr15:7,473,431...7,854,364
Ensembl chr15:5,042,572...5,423,367 		JBrowse link
G Zfp423 zinc finger protein 423 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr19:35,282,149...35,580,775
Ensembl chr19:19,110,238...19,407,373 		JBrowse link
antidepressant type abuse term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmal1 basic helix-loop-helix ARNT like 1 ISO mRNA:increased expression:hippocampal formation (mouse) RGD PMID:15994025 RGD:405866348 NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:167,331,633...167,430,231 		JBrowse link
G Clock clock circadian regulator ISO mRNA:increased expression:hippocampal formation (mouse) RGD PMID:15994025 RGD:405866348 NCBI chr14:32,262,747...32,346,872
Ensembl chr14:31,908,566...31,990,400 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 ISO mRNA:increased expression:hippocampal formation (mouse) RGD PMID:15994025 RGD:405866347 NCBI chr 7:20,417,526...20,481,791
Ensembl chr 7:18,529,823...18,594,091 		JBrowse link
G Per1 period circadian regulator 1 ISO mRNA:decreased expression: hippocampal formation, caudate-putamen (mouse) RGD PMID:15994025 RGD:405866348 NCBI chr10:54,299,002...54,313,804
Ensembl chr10:53,805,535...53,814,431 		JBrowse link
G Per2 period circadian regulator 2 ISO mRNA:increased expression, decreased expression:hippocampal formation, caudate-putamen (mouse) RGD PMID:15994025 RGD:405866348 NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:92,007,296...92,049,459 		JBrowse link
Binge Drinking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase IEP mRNA:decreased expression:basal forebrain cholinergic neurons RGD PMID:37402853 RGD:597538603 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide IEP mRNA:altered exxpression:liver (rat) RGD PMID:23413777 RGD:405100715 NCBI chr 2:229,470,703...229,482,291
Ensembl chr 2:226,797,303...226,808,892 		JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide IEP mRNA:altered exxpression:liver (rat) RGD PMID:23413777 RGD:405100715 NCBI chr 2:229,622,092...229,640,120
Ensembl chr 2:226,947,466...226,987,591 		JBrowse link
G Bdnf brain-derived neurotrophic factor IEP protein:altered expression:amygdala, pyriform cortex, bed nucleus of stria terminalis RGD PMID:23588198 RGD:405849391 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Car3 carbonic anhydrase 3 IEP associated with Alcoholic Liver Diseases;protein:decreased expression:liver RGD PMID:22545783 RGD:7495839 NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP mRNA:increased expression:frontal cortex
mRNA:increased expression:basal forebrain cholinergic neurons		 RGD PMID:23867237 PMID:37402853 RGD:597538460, RGD:597538603 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Chat choline O-acetyltransferase IEP mRNA:decreased expression:basal forebrain cholinergic neurons RGD PMID:37402853 RGD:597538603 NCBI chr16:7,663,665...7,723,416
Ensembl chr16:7,657,362...7,717,093 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit IEP mRNA:decreased expression:basal forebrain cholinergic neurons RGD PMID:37402853 RGD:597538603 NCBI chr 1:126,123,425...126,249,181
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 IEP mRNA:decreased expression:adenohypophysis RGD PMID:11045867 RGD:407431640 NCBI chr10:89,540,192...89,583,466
Ensembl chr10:89,040,203...89,083,481 		JBrowse link
G Cybb cytochrome b-245 beta chain IEP mRNA:increased expression:frontal cortex RGD PMID:23867237 RGD:597538460 NCBI chr  X:16,030,596...16,065,065
Ensembl chr  X:13,359,430...13,392,586 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO
IEP		 associated with Alcoholic Liver Diseases;protein:increased expression:liver
mRNA:altered exxpression:liver (rat)
protein:increased expression, increased nitration 		RGD PMID:25236742 PMID:22545783 PMID:23413777 PMID:29404485 PMID:25236742 RGD:14700891, RGD:7495839, RGD:405100715, RGD:14700911, RGD:14700891 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO protein:increased expression:nucleus accumbens: RGD PMID:23423140 RGD:9588287 NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Drd1 dopamine receptor D1 IEP associated with human immunodeficiency virus infectious disease;mRNA:altered expression:liver,spleen (rat) RGD PMID:23413777 RGD:405100715 NCBI chr17:10,545,488...10,550,029
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 IEP mRNA:altered exxpression:spleen (rat) RGD PMID:23413777 RGD:405100715 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 IEP associated with human immunodeficiency virus infectious disease;mRNA:altered expression:liver,spleen (rat) RGD PMID:23413777 RGD:405100715 NCBI chr11:70,385,586...70,437,793
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Drd4 dopamine receptor D4 susceptibility ISO
IEP		 DNA:repeats:exon:
mRNA:altered exxpression:spleen (rat)		 RGD PMID:19393859 PMID:23413777 RGD:401960068, RGD:405100715 NCBI chr 1:205,825,937...205,829,124
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Efhd2 EF-hand domain family, member D2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28397836 NCBI chr 5:159,443,959...159,459,993
Ensembl chr 5:154,160,946...154,176,980 		JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 IEP mRNA:increased expression:basal forebrain cholinergic neurons RGD PMID:37402853 RGD:597538603 NCBI chr20:3,924,263...3,941,238
Ensembl chr20:3,919,624...3,941,547 		JBrowse link
G Fn1 fibronectin 1 IEP mRNA:increased expression:frontal cortex RGD PMID:23867237 RGD:597538460 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit IEP protein:increased expression:prefrontal cortex RGD PMID:29407478 RGD:405295494 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 IEP associated with human immunodeficiency virus infectious disease;mRNA:altered expression:liver,spleen (rat) RGD PMID:23413777 RGD:405100715 NCBI chr10:27,096,731...27,152,563
Ensembl chr10:26,595,160...26,650,864 		JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 IEP associated with human immunodeficiency virus infectious disease;mRNA:altered expression:liver,spleen (rat) RGD PMID:23413777 RGD:405100715 NCBI chr14:37,451,218...37,587,458
Ensembl chr14:37,097,279...37,228,944 		JBrowse link
G Gabra3 gamma-aminobutyric acid type A receptor subunit alpha 3 IEP associated with human immunodeficiency virus infectious disease;mRNA:altered expression:liver,spleen (rat) RGD PMID:23413777 RGD:405100715 NCBI chr  X:155,301,979...155,543,870
Ensembl chr  X:150,261,607...150,501,559 		JBrowse link
G Gabra6 gamma-aminobutyric acid type A receptor subunit alpha6 IEP mRNA:altered exxpression:spleen (rat) RGD PMID:23413777 RGD:405100715 NCBI chr10:27,311,965...27,327,337
Ensembl chr10:26,810,423...26,825,769 		JBrowse link
G Gdnf glial cell derived neurotrophic factor IMP
IEP		 protein:altered expression:amygdala, pyriform cortex, bed nucleus of stria terminalis RGD PMID:23298382 PMID:23588198 RGD:405849390, RGD:405849391 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Gpx1 glutathione peroxidase 1 IEP protein:decreased expression:liver RGD PMID:25864381 RGD:401827870 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gpx3 glutathione peroxidase 3 IEP protein:decreased expression:serum RGD PMID:25864381 RGD:401827870 NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Gpx4 glutathione peroxidase 4 IEP protein:decreased expression:liver RGD PMID:25864381 RGD:401827870 NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:9,650,185...9,652,982 		JBrowse link
G Grm2 glutamate metabotropic receptor 2 IEP associated with human immunodeficiency virus infectious disease;mRNA:altered expression:liver,spleen (rat) RGD PMID:23413777 RGD:405100715 NCBI chr 8:116,158,810...116,171,857
Ensembl chr 8:107,280,099...107,293,146 		JBrowse link
G Grm5 glutamate metabotropic receptor 5 IEP associated with human immunodeficiency virus infectious disease;mRNA:altered expression:liver,spleen (rat) RGD PMID:23413777 RGD:405100715 NCBI chr 1:150,722,711...151,297,585
Ensembl chr 1:141,312,368...141,882,274 		JBrowse link
G Hmgb1 high mobility group box 1 ISO
IEP		 mRNA, protein:increased expression:brain
mRNA:increased expression:basal forebrain cholinergic neurons		 RGD PMID:23206318 PMID:37402853 RGD:7175526, RGD:597538603 NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Il1b interleukin 1 beta IEP mRNA:increased expression:basal forebrain cholinergic neurons RGD PMID:37402853 RGD:597538603 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Lhx8 LIM homeobox 8 IEP mRNA:decreased expression:basal forebrain cholinergic neurons RGD PMID:37402853 RGD:597538603 NCBI chr 2:245,904,712...245,929,376
Ensembl chr 2:243,244,961...243,269,416 		JBrowse link
G Mir125a microRNA 125a IEP RNA:decreased expression:neuron RGD PMID:27085842 RGD:26884454 NCBI chr 1:67,350,675...67,350,759
Ensembl chr 1:58,677,626...58,677,710 		JBrowse link
G Mir223 microRNA 223 ISO RNA:increased expression:serum
RNA:increased expression:serum, neutrophil,liver		 RGD PMID:27679493 PMID:27679493 RGD:21408575, RGD:21408575 NCBI chr  X:65,151,383...65,151,492
Ensembl chr  X:61,141,887...61,141,996 		JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II IEP mRNA:increased expression:frontal cortex RGD PMID:23867237 RGD:597538460 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor IEP mRNA:increased expression:frontal cortex RGD PMID:23867237 RGD:597538460 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Ngfr nerve growth factor receptor IEP mRNA:decreased expression:basal forebrain cholinergic neurons RGD PMID:37402853 RGD:597538603 NCBI chr10:81,012,077...81,030,305
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 ameliorates ISO protein:decreased expression:central amygdaloid nucleus (mouse) RGD PMID:30647448 PMID:22218088 RGD:402463940, RGD:405096664 NCBI chr16:27,804,416...27,814,070
Ensembl chr16:23,037,789...23,046,759 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 treatment IMP RGD PMID:22500955 RGD:408361838 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Ntsr2 neurotensin receptor 2 IEP mRNA,protein:altered expression:anterior paraventricular nucleus of thalamus RGD PMID:32623746 RGD:596948426 NCBI chr 6:45,153,095...45,159,783
Ensembl chr 6:39,424,324...39,431,014 		JBrowse link
G Oprl1 opioid related nociceptin receptor 1 ISO RGD PMID:29197086 RGD:14348965 NCBI chr 3:189,209,495...189,225,406
Ensembl chr 3:168,834,003...168,839,920 		JBrowse link
G Per2 period circadian regulator 2 ISO DNA, mRNA:hypermethylation, decreased expression:blood RGD PMID:30597578 RGD:405878075 NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:92,007,296...92,049,459 		JBrowse link
G Pomc proopiomelanocortin ISO
IEP		 DNA, mRNA:hypermethylation, decreased expression:blood
protein:decreased expression:central amygdaloid nucleus, arcuate and paraventricular nucleus of hypothalamus
mRNA:decreased expression:hypothalamus		 RGD PMID:30597578 PMID:23792540 PMID:11045867 RGD:405878075, RGD:407571694, RGD:407431640 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Rest RE1-silencing transcription factor IEP mRNA:increased expression:basal forebrain cholinergic neurons RGD PMID:37402853 RGD:597538603 NCBI chr14:31,213,415...31,233,451
Ensembl chr14:30,862,553...30,894,354 		JBrowse link
G S100b S100 calcium binding protein B IEP mRNA:increased expression:frontal cortex RGD PMID:23867237 RGD:597538460 NCBI chr20:12,372,345...12,381,159
Ensembl chr20:12,372,881...12,394,743 		JBrowse link
G Sirt1 sirtuin 1 IEP RGD PMID:24416161 RGD:9495933 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Slc18a3 solute carrier family 18 member A3 IEP mRNA:decreased expression:basal forebrain cholinergic neurons RGD PMID:37402853 RGD:597538603 NCBI chr16:7,719,953...7,722,814 JBrowse link
G Slc23a2 solute carrier family 23 member 2 IEP RGD PMID:27085842 RGD:26884454 NCBI chr 3:139,755,583...139,913,304
Ensembl chr 3:119,302,666...119,460,343 		JBrowse link
G Tlr2 toll-like receptor 2 sexual_dimorphism ISO mRNA, protein:increased expression:brain
mRNA:increased expression:adipose tissue		 RGD PMID:23206318 PMID:27711160 RGD:7175526, RGD:407424601 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr3 toll-like receptor 3 ISO mRNA, protein:increased expression:brain RGD PMID:23206318 RGD:7175526 NCBI chr16:53,554,916...53,572,321
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr4 toll-like receptor 4 ISO mRNA, protein:increased expression:brain RGD PMID:23206318 RGD:7175526 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor IEP mRNA:increased expression:frontal cortex RGD PMID:23867237 RGD:597538460 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tph2 tryptophan hydroxylase 2 susceptibility ISO DNA:SNPs: :rs7963717, rs11178999, rs17110451 RGD PMID:29697747 RGD:597621695 NCBI chr 7:52,571,909...52,676,305
Ensembl chr 7:50,685,694...50,789,424 		JBrowse link
cannabis abuse term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19625010 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21041608 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Apol2 apolipoprotein L2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr 7:111,211,944...111,219,209
Ensembl chr 7:109,331,392...109,338,558 		JBrowse link
G Bche butyrylcholinesterase ISO protein:increased activity:blood plasma (human) RGD PMID:30707402 RGD:401960085 NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Bdnf brain-derived neurotrophic factor IEP protein:decreased expression:frontal cortex, hippocampus RGD PMID:22083592 RGD:597015776 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Calm1 calmodulin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr 6:125,217,191...125,227,855
Ensembl chr 6:119,487,621...119,498,227 		JBrowse link
G Calm2 calmodulin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr 6:12,845,170...12,857,830
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr14:85,059,166...85,148,121
Ensembl chr14:80,845,238...80,933,994 		JBrowse link
G Cnr1 cannabinoid receptor 1 ISO
IMP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19016476 PMID:21187978 RGD:596933102 NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Comt catechol-O-methyltransferase susceptibility
onset		 ISO DNA:SNP:cd: p.V158M (human)
associated with alcohol use disorder; DNA:hypermethylation:promoter		 RGD PMID:19259017 PMID:33781176 PMID:30790675 RGD:401959590, RGD:401959741, RGD:401959592 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Drd4 dopamine receptor D4 susceptibility ISO DNA:duplication:promoter: 120bp repeat RGD PMID:33544778 RGD:401959602 NCBI chr 1:205,825,937...205,829,124
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr15:41,588,114...41,616,168
Ensembl chr15:37,412,146...37,440,287 		JBrowse link
G Gcc1 GRIP and coiled-coil domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr 4:57,996,261...58,008,126
Ensembl chr 4:57,032,314...57,042,663 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 IMP RGD PMID:21187978 RGD:596933102 NCBI chr 2:168,247,490...168,367,616
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B IMP RGD PMID:21187978 RGD:596933102 NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Ngf nerve growth factor ISO protein:decreased expression:serum RGD PMID:18774699 RGD:401965396 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Nrg1 neuregulin 1 ISO associated with schizophrenia;protein:increased expression:blood: RGD PMID:30799217 RGD:405112241 NCBI chr16:65,954,084...67,007,484
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 IEP protein:decreased expression:hippocampus RGD PMID:22083592 RGD:597015776 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr12:36,957,302...37,023,982
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
cannabis dependence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A susceptibility ISO DNA:SNP: :3435C>T (rs1045642) (human) RGD PMID:19625010 RGD:401901192 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Ache acetylcholinesterase susceptibility ISO protein:increased activity:blood
DNA:SNP:3'UTR:rs17228602 (human)		 RGD PMID:31129131 PMID:31129131 RGD:405855848, RGD:405855848 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Comt catechol-O-methyltransferase ISO DNA:hypermethylation:promoter RGD PMID:24902721 RGD:401940112 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Hcrt hypocretin neuropeptide precursor ISO mRNA:increased expression:blood (human) RGD PMID:22846875 RGD:401960066 NCBI chr10:86,190,289...86,191,524
Ensembl chr10:85,689,465...85,691,210 		JBrowse link
G Nrg1 neuregulin 1 susceptibility ISO DNA:SNP: :rs17664708(human) RGD PMID:22520967 RGD:405115756 NCBI chr16:65,954,084...67,007,484
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
cocaine abuse term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bche butyrylcholinesterase severity ISO RGD PMID:21540357 RGD:401960084 NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Bdnf brain-derived neurotrophic factor ISO mRNA:increased expression:nucleus accumbens RGD PMID:31280332 RGD:596948400 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 ISO mRNA:decreased expression:caudate-putamen (mouse) RGD PMID:15994025 RGD:405866348 NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:167,331,633...167,430,231 		JBrowse link
G Cartpt CART prepropeptide ISO mRNA:increased expression:nucleus accumbens RGD PMID:15009677 RGD:597805894 NCBI chr 2:32,989,215...32,991,794
Ensembl chr 2:31,255,098...31,290,713 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 severity ISO RGD PMID:21806491 RGD:401794583 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Cd40lg CD40 ligand severity ISO RGD PMID:21806491 RGD:401794583 NCBI chr  X:140,164,341...140,176,057
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit onset ISO DNA:SNP:exon:rs16969968(human) RGD PMID:32841724 RGD:150530292 NCBI chr 8:64,265,879...64,294,233
Ensembl chr 8:55,369,794...55,398,146 		JBrowse link
G Chrna6 cholinergic receptor nicotinic alpha 6 subunit susceptibility ISO DNA:SNP::rs892413(human) RGD PMID:24675634 RGD:405849277 NCBI chr16:71,400,615...71,407,315
Ensembl chr16:64,697,741...64,704,441 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit onset ISO DNA:SNP::rs950776(human) RGD PMID:32841724 RGD:150530292 NCBI chr 8:64,312,644...64,333,319
Ensembl chr 8:55,418,313...55,437,027 		JBrowse link
G Clock clock circadian regulator ISO mRNA:increased expression:caudate-putamen (mouse) RGD PMID:15994025 RGD:405866348 NCBI chr14:32,262,747...32,346,872
Ensembl chr14:31,908,566...31,990,400 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 ISO
IDA		 protein:increased expression, increased phosphorylation:prefrontal cortex RGD PMID:24205196 PMID:18001273 RGD:401940185, RGD:401959587 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 ISO mRNA:decreased expression:caudate-putamen (mouse) RGD PMID:15994025 RGD:405866347 NCBI chr 7:20,417,526...20,481,791
Ensembl chr 7:18,529,823...18,594,091 		JBrowse link
G Fgf2 fibroblast growth factor 2 IEP mRNA:increased expression:nucleus accumbens (rat) RGD PMID:27114539 RGD:405855871 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 sexual_dimorphism IEP mRNA:increased expression:brain (rat) RGD PMID:31029877 RGD:401976486 NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,457,216...6,541,674 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit treatment ISO RGD PMID:28366798 RGD:405100962 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit IEP
ISO		 associated with alcohol dependence;protein:increased expression: caudate-putamen (rat) RGD PMID:17572394 PMID:9294222 RGD:401900302, RGD:407446380 NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 sexual_dimorphism ISO
IEP		 protein:increased expression:prefrontal cortex (mouse)
protein:increased expression:nucleus accumbens (rat)
protein:decreased expression:nucleus accumbens (mouse)		 RGD PMID:33497752 PMID:11801363 PMID:22197517 RGD:401976469, RGD:405650201, RGD:405650197 NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Hcrt hypocretin neuropeptide precursor treatment ISO RGD PMID:29454841 RGD:401960065 NCBI chr10:86,190,289...86,191,524
Ensembl chr10:85,689,465...85,691,210 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A IEP protein:decreased expression:dentate gyrus, hypothalamus RGD PMID:9723786 RGD:401900605 NCBI chr 2:38,427,169...38,431,733
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A treatment IEP
IMP		 mRNA:increased expression:orbitofrontal cortex RGD PMID:27733540 PMID:20814782 PMID:11259563 RGD:401900753, RGD:401901179, RGD:401900755 NCBI chr15:56,360,647...56,428,703
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C treatment IMP RGD PMID:20814782 RGD:401901179 NCBI chr  X:115,453,190...115,682,325
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 IDA protein:increased phosphorylation:nucleus accumbens RGD PMID:25522720 RGD:401851063 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 IDA protein:increased phosphorylation:nucleus accumbens RGD PMID:25522720 RGD:401851063 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mb myoglobin ISO protein:increased expression:umbilical cord blood RGD PMID:8989474 RGD:458925290 NCBI chr 7:110,640,511...110,647,742
Ensembl chr 7:108,759,904...108,767,383 		JBrowse link
G Npas2 neuronal PAS domain protein 2 ISO mRNA:decreased expression:hippocampal formation,caudate-putamen (mouse) RGD PMID:15994025 RGD:405866347 NCBI chr 9:48,959,225...49,138,036
Ensembl chr 9:41,463,830...41,642,320 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 susceptibility ISO DNA:SNP:intron: (rs4518200) (human) RGD PMID:33242852 RGD:402463938 NCBI chr16:27,804,416...27,814,070
Ensembl chr16:23,037,789...23,046,759 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 treatment IMP
ISO		 mRNA:decreased expression:blood RGD PMID:12805318 PMID:29761890 PMID:9765324 RGD:401976288, RGD:407987269, RGD:401976376 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 treatment ISO mRNA:increased expression:nucleus accumbens RGD PMID:27576164 PMID:31280332 RGD:596948399, RGD:596948400 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Pdyn prodynorphin IEP mRNA:increased expression:caudate putamen
mRNA:increased expression:central amygdaloid nucleus, dentate gyrus of hippocampal formation		 RGD PMID:7694032 PMID:12523490 RGD:401850578, RGD:401850585 NCBI chr 3:137,354,161...137,366,503
Ensembl chr 3:116,900,992...116,913,334 		JBrowse link
G Per1 period circadian regulator 1 ISO mRNA:increased expression:hippocampal formation, caudate-putamen (mouse) RGD PMID:15994025 RGD:405866348 NCBI chr10:54,299,002...54,313,804
Ensembl chr10:53,805,535...53,814,431 		JBrowse link
G Per2 period circadian regulator 2 ISO mRNA:increased expression, decreased expression:hippocampal formation, caudate-putamen (mouse) RGD PMID:15994025 RGD:405866348 NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:92,007,296...92,049,459 		JBrowse link
G Prl prolactin treatment ISO RGD PMID:17391744 RGD:401960113 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Tlr2 toll-like receptor 2 ISO protein:increased expression:striatum, microglial cell RGD PMID:26860188 RGD:597538483 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
cocaine dependence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr2a activin A receptor type 2A ameliorates IMP RGD PMID:26030849 RGD:597830060 NCBI chr 3:53,614,143...53,701,933
Ensembl chr 3:33,205,523...33,289,968 		JBrowse link
G Ankk1 ankyrin repeat and kinase domain containing 1 treatment ISO DNA:SNP: :rs1800497(human) RGD PMID:23635803 RGD:401959203 NCBI chr 8:58,676,327...58,685,012
Ensembl chr 8:49,779,862...49,788,024 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein ISO protein:increased expression:dorsal striatum, shell of nucleus accumbens (mouse) RGD PMID:27567310 RGD:401901591 NCBI chr 7:108,444,959...108,448,413
Ensembl chr 7:106,555,785...106,559,378 		JBrowse link
G Avp arginine vasopressin IEP protein:increased expression:nucleus accumbens RGD PMID:19596360 RGD:408426004 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Bdnf brain-derived neurotrophic factor ISO
IMP		 RGD PMID:14973246 PMID:18990365 RGD:401965389, RGD:596933098 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV no_association ISO DNA:SNP: :rs919334
DNA:SNPs: :rs1457115, rs9285875		 RGD PMID:19001277 PMID:19001277 RGD:401938643, RGD:401938643 NCBI chr18:24,857,152...25,076,054
Ensembl chr18:24,585,269...24,802,487 		JBrowse link
G Ccser1 coiled-coil serine-rich protein 1 susceptibility ISO DNA:SNP:: (rs1381355) (human) RGD PMID:18438686 RGD:401851917 NCBI chr 4:91,483,896...92,720,439
Ensembl chr 4:90,292,780...91,388,786 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit susceptibility ISO DNA:missense:exons:p.R37H,p.E363D(human) RGD PMID:24057674 RGD:405849397 NCBI chr 8:64,297,755...64,311,251
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit susceptibility ISO DNA:missense:exons:multiple(human) RGD PMID:24057674 RGD:405849397 NCBI chr16:71,411,847...71,454,225
Ensembl chr16:64,714,169...64,751,360 		JBrowse link
G Comt catechol-O-methyltransferase susceptibility ISO DNA:SNPs,haplotypes:exon: p.V158M (rs4680, rs737865, rs165688) (human) RGD PMID:18704099 RGD:401959302 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 treatment
sexual_dimorphism
no_association		 IEP
IDA
ISO		 protein:increased phosphorylation:nucleus accumbens
protein:increased phosphorylation:nucleus accumbens, prefrontal cortex
DNA:SNPs: :rs10876469, rs2177000		 RGD PMID:27664298 PMID:25522720 PMID:23665060 PMID:19001277 RGD:401900166, RGD:401851063, RGD:401851078, RGD:401938643 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Drd2 dopamine receptor D2 sexual_dimorphism
treatment		 IMP
ISO		 female only;DNA:SNP: :rs2283265(human) RGD PMID:29454035 PMID:30367264 PMID:23635803 RGD:13506950, RGD:401959597, RGD:401959203 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Egr1 early growth response 1 treatment IEP RGD PMID:26674058 RGD:405100964 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit treatment
severity		 IEP protein:increased expression:habenula
mRNA:increased expression:brain
protein:increased expression:brain		 RGD PMID:26674058 PMID:29139213 PMID:18488248 PMID:18310906 PMID:24633559 RGD:405100964, RGD:401900161, RGD:401959615, RGD:405101699, RGD:405100965 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit treatment
ameliorates		 IEP
ISO		 protein:increased expression:Nucleus Accumbens, Caudate Putamen (rat)
protein:increased expression:dorsal striatum, nucelus accumbens (mouse)
mRNA,protein:increased expression:Nucleus Accumbens, Caudate Putamen (rat)
protein:increased expression:Brain (rat)		 RGD PMID:25522720 PMID:27380261 PMID:20633205 PMID:27664298 PMID:22403532 More... RGD:401851063, RGD:401901287, RGD:401900126, RGD:401900166, RGD:401851084, RGD:401851078 NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 susceptibility ISO DNA:SNP:intron: C>G (rs29220) (human)
mRNA:decreased expression:hippocampus (human)		 RGD PMID:22253714 PMID:26727527 RGD:401900163, RGD:11552767 NCBI chr20:1,469,779...1,499,352
Ensembl chr20:1,464,534...1,493,994 		JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 ISO mRNA:decreased expression:hippocampus (human) RGD PMID:22253714 RGD:401900163 NCBI chr10:26,876,926...26,965,523
Ensembl chr10:26,374,694...26,464,346 		JBrowse link
G Gad1 glutamate decarboxylase 1 ISO mRNA:decreased expression:hippocampus RGD PMID:22253714 RGD:401900163 NCBI chr 3:75,777,260...75,818,099
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gad2 glutamate decarboxylase 2 ISO mRNA:decreased expression:hippocampus RGD PMID:22253714 RGD:401900163 NCBI chr17:89,671,718...89,734,246
Ensembl chr17:84,763,628...84,826,155 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 treatment
exacerbates		 IMP
IEP
ISO		 protein:increased expression:nucleus accumbens (rat)
protein:increased expression, increased phosphorylation:hippocampal formation, postsynaptic density (mouse)
protein:increased expression:nucleus accumbens cell surface (rat)
protein:increased phosphorylation:prefrontal cortex, premotor cortex (rat)
protein:increased phosphorylation:hippocampal formation (mouse)
protein:increased expression:ventral tegmental area (rat)		 RGD PMID:18430032 PMID:18500330 PMID:22127928 PMID:16794574 PMID:29089442 More... RGD:405096666, RGD:408364954, RGD:405820210, RGD:405820206, RGD:405818277, RGD:405818274, RGD:405650670, RGD:405650586, RGD:405649734, RGD:405649733, RGD:405649730, RGD:405100712 NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 treatment IMP RGD PMID:20555310 RGD:408364961 NCBI chr 2:168,247,490...168,367,616
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 susceptibility ISO DNA:polymorphism:CDS:p.Ile105Val RGD PMID:16272961 RGD:597621685 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A treatment ISO
IMP		 DNA:SNP: :rs6561333 RGD PMID:23241418 PMID:15849375 PMID:23336050 RGD:401900299, RGD:401900756, RGD:401900743 NCBI chr15:56,360,647...56,428,703
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C treatment IMP RGD PMID:23336050 RGD:401900743 NCBI chr  X:115,453,190...115,682,325
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A ISO DNA:SNPs, haplotype:exon, intron: (rs1985242, rs2276302, rs4938066) (human)
DSNA:SNP:intron:g.113985089A>G (rs897687) (human)		 RGD PMID:24590108 PMID:26227246 RGD:404976878, RGD:405096480 NCBI chr 8:58,138,514...58,150,960
Ensembl chr 8:49,242,020...49,254,389 		JBrowse link
G Klhl5 kelch-like family member 5 susceptibility ISO DNA:SNP:: (rs1046655) (human) RGD PMID:18438686 RGD:401851917 NCBI chr14:43,497,915...43,565,833
Ensembl chr14:43,144,257...43,184,238 		JBrowse link
G Lrrc7 leucine rich repeat containing 7 susceptibility ISO DNA:SNP: (rs1938584) (human) RGD PMID:18438686 RGD:401851917 NCBI chr 2:249,792,441...250,294,267
Ensembl chr 2:247,147,752...247,634,547 		JBrowse link
G Manea mannosidase, endo-alpha susceptibility ISO DNA:SNPs:multiple RGD PMID:19255376 RGD:401851915 NCBI chr 5:44,992,937...45,015,084
Ensembl chr 5:40,196,396...40,218,459 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 IDA protein:increased phosphorylation:brain RGD PMID:23665060 RGD:401851078 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 IDA protein:increased phosphorylation:brain RGD PMID:23665060 RGD:401851078 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Ngf nerve growth factor ISO protein:decreased expression:serum RGD PMID:17715210 RGD:401976440 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IEP mRNA:decreased expression:adenohypophysis RGD PMID:12892653 RGD:408345227 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 treatment IMP RGD PMID:18990365 PMID:31417375 PMID:27488635 RGD:596933098, RGD:596933359, RGD:596933099 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Oprd1 opioid receptor, delta 1 susceptibility
treatment		 ISO DNA:SNP,haplotype:intron 1 (rs2298896|rs421300), multiple GCAAT (human)
DNA:SNPs, haplotype:intron 1 (rs2298896|rs421300) (human)
associated with alcohol use disorder; DNA:SNP:intron (rs678849) (human)
associated with opiate dependence;DNA:SNP:intron (rs678849) (human)
DNA:SNP:intron,cds (rs678849,rs2234918) (human)		 RGD PMID:17622222 PMID:24533225 PMID:27449273 PMID:33953123 PMID:22795689 RGD:401976552, RGD:402525443, RGD:402463960, RGD:402463937, RGD:401976559 NCBI chr 5:149,590,244...149,624,999
Ensembl chr 5:144,306,188...144,340,960 		JBrowse link
G Oprk1 opioid receptor, kappa 1 ISO DNA:SNPs:intron:rs6473797, rs10111937 RGD PMID:34843875 RGD:401851040 NCBI chr 5:18,657,866...18,675,671
Ensembl chr 5:13,860,021...13,877,823 		JBrowse link
G Oprm1 opioid receptor, mu 1 ISO mRNA:increased expression:nucleus accumbens RGD PMID:29992335 RGD:401831041 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Pdyn prodynorphin susceptibility ISO DNA, mRNA:SNPs, haplotype:3' utr:rs910080, rs910079, rs2235749 (human)
mRNA:increased expression:nucleus accumbens
mRNA:increased expression:caudate-putamen
DNA:VNTR:Promoter		 RGD PMID:18923396 PMID:22390687 PMID:23164614 PMID:16184603 RGD:401850550, RGD:401851043, RGD:401850589, RGD:401850583 NCBI chr 3:137,354,161...137,366,503
Ensembl chr 3:116,900,992...116,913,334 		JBrowse link
G Per2 period circadian regulator 2 susceptibility ISO DNA:repeats:: RGD PMID:22832851 RGD:401976513 NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:92,007,296...92,049,459 		JBrowse link
G Ppbp pro-platelet basic protein ISO protein:increased expression:plasma RGD PMID:21806491 RGD:401794583 NCBI chr14:17,586,495...17,587,299
Ensembl chr14:17,302,326...17,303,130 		JBrowse link
G Prl prolactin severity ISO protein:decreased expression:blood serum (human)
protein:increased expression:blood plasma (human)
protein:increased expression:blood serum (human)		 RGD PMID:16915581 PMID:2243892 PMID:15064918 RGD:401959377, RGD:401960099, RGD:401959381 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Rabep2 rabaptin, RAB GTPase binding effector protein 2 IEP protein:increased expression:brain RGD PMID:9789813 RGD:405255653 NCBI chr 1:190,433,501...190,457,241
Ensembl chr 1:181,010,305...181,026,648 		JBrowse link
G Sirt1 sirtuin 1 IEP protein:increased expression:brain, nucleus accumbens (rat) RGD PMID:27664298 RGD:401900166 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sirt2 sirtuin 2 treatment IEP RGD PMID:27664298 RGD:401900166 NCBI chr 1:93,181,472...93,204,499
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
G Smad3 SMAD family member 3 ameliorates IMP RGD PMID:27422367 PMID:26030849 RGD:597830063, RGD:597830060 NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smarca4 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4 ameliorates IMP RGD PMID:27422367 RGD:597830063 NCBI chr 8:28,438,370...28,535,071
Ensembl chr 8:20,167,717...20,258,975 		JBrowse link
G Tenm3 teneurin transmembrane protein 3 susceptibility ISO DNA:SNP:: (rs1514483) (human) RGD PMID:18438686 RGD:401851917 NCBI chr16:47,984,732...50,711,352
Ensembl chr16:41,252,182...43,978,594 		JBrowse link
G Tph2 tryptophan hydroxylase 2 treatment ISO DNA:SNP: :rs4290270 RGD PMID:22925276 RGD:597805898 NCBI chr 7:52,571,909...52,676,305
Ensembl chr 7:50,685,694...50,789,424 		JBrowse link
Cocaine-Related Disorders term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase treatment IMP RGD PMID:22128851 RGD:9588542 NCBI chr10:7,503,351...7,599,474
Ensembl chr10:6,999,819...7,092,835 		JBrowse link
G Ago2 argonaute RISC catalytic component 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20643829 NCBI chr 7:106,907,209...106,994,124
Ensembl chr 7:105,029,120...105,104,974 		JBrowse link
G Apol2 apolipoprotein L2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr 7:111,211,944...111,219,209
Ensembl chr 7:109,331,392...109,338,558 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:18311559 NCBI chr 7:108,444,959...108,448,413
Ensembl chr 7:106,555,785...106,559,378 		JBrowse link
G Atp9b ATPase phospholipid transporting 9B (putative) ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438686 NCBI chr18:76,451,821...76,643,931
Ensembl chr18:74,176,863...74,368,953 		JBrowse link
G Avp arginine vasopressin susceptibility ISO DNA:SNP:intron: (rs2282018) (human) RGD PMID:24766650 RGD:401976505 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Bche butyrylcholinesterase ISO CTD Direct Evidence: therapeutic CTD PMID:18292872 PMID:18514640 PMID:20060817 PMID:20971807 PMID:22935511 More... NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Bdnf brain-derived neurotrophic factor severity
susceptibility		 ISO
IMP		 CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:14973246 PMID:17618281 PMID:17651427 PMID:18311559 PMID:19321768 More... RGD:38501054, RGD:38501054 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bdnfem1Sage brain-derived neurotrophic factor; ZFN induced mutant 1, Sage severity IMP RGD PMID:23583595 RGD:38501054
G Calm1 calmodulin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr 6:125,217,191...125,227,855
Ensembl chr 6:119,487,621...119,498,227 		JBrowse link
G Calm2 calmodulin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr 6:12,845,170...12,857,830
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:14725635 NCBI chr18:56,648,779...56,711,505
Ensembl chr18:54,378,784...54,438,994 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr14:85,059,166...85,148,121
Ensembl chr14:80,845,238...80,933,994 		JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV ISO CTD Direct Evidence: marker/mechanism CTD PMID:19001277 NCBI chr18:24,857,152...25,076,054
Ensembl chr18:24,585,269...24,802,487 		JBrowse link
G Cartpt CART prepropeptide ISO CTD Direct Evidence: therapeutic CTD PMID:20886038 NCBI chr 2:32,989,215...32,991,794
Ensembl chr 2:31,255,098...31,290,713 		JBrowse link
G Cckbr cholecystokinin B receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:9922984 NCBI chr 1:169,183,578...169,193,583
Ensembl chr 1:159,771,733...159,814,881 		JBrowse link
G Ccser1 coiled-coil serine-rich protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438686 NCBI chr 4:91,483,896...92,720,439
Ensembl chr 4:90,292,780...91,388,786 		JBrowse link
G Cdk5 cyclin-dependent kinase 5 ISO RGD PMID:11268215 RGD:734739 NCBI chr 4:11,647,098...11,651,606
Ensembl chr 4:10,754,687...10,760,112 		JBrowse link
G Ces1d carboxylesterase 1D ISO CTD Direct Evidence: therapeutic CTD PMID:12679808 PMID:12773168 NCBI chr19:30,046,494...30,085,039
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Ces2h carboxylesterase 2H ISO CTD Direct Evidence: therapeutic CTD PMID:19710369 NCBI chr19:49,884,164...49,898,764
Ensembl chr19:32,974,242...32,988,830 		JBrowse link
G Cfl1 cofilin 1 IEP protein:altered expression:striatum (rat) RGD PMID:27018876 RGD:11568696 NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:202,786,627...202,817,587 		JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:13130510 NCBI chr 3:119,739,229...119,791,630
Ensembl chr 3:99,284,846...99,337,252 		JBrowse link
G Cnr1 cannabinoid receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16314880 PMID:17596442 PMID:19052543 NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Comt catechol-O-methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18704099 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11717377 PMID:16359811 PMID:18596687 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crh corticotropin releasing hormone IEP
ISO		 mRNA:decreased expression:hypothalamus (rat)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:7796157 PMID:10516337 PMID:11797056 PMID:18596687 PMID:19349312 More... RGD:5508177 NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Crhbp corticotropin releasing hormone binding protein susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:SNP:3'UTR: (rs1875999) (HUMAN)		 CTD
RGD		 PMID:17437087 PMID:24766650 RGD:401976505 NCBI chr 2:28,427,139...28,439,446
Ensembl chr 2:26,692,403...26,704,710 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 IEP
ISO		 mRNA:increased expression:anterior pituitary (rat)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:19339610 PMID:12576179 RGD:5508175 NCBI chr10:89,540,192...89,583,466
Ensembl chr10:89,040,203...89,083,481 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17437087 NCBI chr 4:85,553,163...85,596,203
Ensembl chr 4:84,224,002...84,265,904 		JBrowse link
G Dnah8 dynein, axonemal, heavy chain 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438686 NCBI chr20:8,694,371...8,948,849
Ensembl chr20:8,692,963...8,946,772 		JBrowse link
G Drd1 dopamine receptor D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15295029 PMID:16014726 PMID:16541082 PMID:20456009 NCBI chr17:10,545,488...10,550,029
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 IDA
ISO		 protein:increased activity:caudate putamen (rat)
CTD Direct Evidence: marker/mechanism|therapeutic		 CTD
RGD		 PMID:10900248 PMID:11751029 PMID:11923462 PMID:15010698 PMID:15042275 More... RGD:2311586 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:10523822 PMID:15100700 PMID:17332411 PMID:18566292 PMID:20494958 NCBI chr11:70,385,586...70,437,793
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Egr1 early growth response 1 treatment IEP
ISO		 CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:16157275 PMID:16738229 PMID:18311559 PMID:25309368 PMID:21309948 RGD:10395309, RGD:10400880 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 ISO CTD Direct Evidence: therapeutic CTD PMID:20056891 NCBI chr20:3,924,263...3,941,238
Ensembl chr20:3,919,624...3,941,547 		JBrowse link
G Esr2 estrogen receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17133264 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr15:41,588,114...41,616,168
Ensembl chr15:37,412,146...37,440,287 		JBrowse link
G Fgf2 fibroblast growth factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19014962 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit ISO
IEP		 CTD Direct Evidence: marker/mechanism
protein:increased expression:brain		 CTD
RGD		 PMID:17276011 PMID:18311559 PMID:19533625 PMID:14741756 RGD:405255650 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:12657709 PMID:17898221 PMID:18539927 PMID:19331462 NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase ameliorates ISO RGD PMID:35185557 RGD:408345254 NCBI chr20:44,322,635...44,514,498
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22253714 NCBI chr20:1,469,779...1,499,352
Ensembl chr20:1,464,534...1,493,994 		JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19833324 PMID:20133874 NCBI chr14:37,451,218...37,587,458
Ensembl chr14:37,097,279...37,228,944 		JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22253714 NCBI chr10:26,876,926...26,965,523
Ensembl chr10:26,374,694...26,464,346 		JBrowse link
G Gad1 glutamate decarboxylase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22253714 NCBI chr 3:75,777,260...75,818,099
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gad2 glutamate decarboxylase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22253714 NCBI chr17:89,671,718...89,734,246
Ensembl chr17:84,763,628...84,826,155 		JBrowse link
G Galr1 galanin receptor 1 susceptibility ISO DNA:SNP:intron: (rs2717162) (human) RGD PMID:24766650 RGD:401976505 NCBI chr18:78,046,803...78,062,359
Ensembl chr18:75,772,023...75,787,577 		JBrowse link
G Gcc1 GRIP and coiled-coil domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr 4:57,996,261...58,008,126
Ensembl chr 4:57,032,314...57,042,663 		JBrowse link
G Gdnf glial cell derived neurotrophic factor ISO CTD Direct Evidence: therapeutic CTD PMID:14622243 PMID:15899247 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:17407494 NCBI chr 4:148,421,315...148,431,128
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Gphn gephyrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:22253714 NCBI chr 6:102,687,405...103,216,679
Ensembl chr 6:96,892,148...97,483,612 		JBrowse link
G Gpsm1 G-protein signaling modulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15091342 NCBI chr 3:29,538,929...29,565,921
Ensembl chr 3:9,128,636...9,167,827 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:14684464 PMID:15764012 PMID:16495937 PMID:18430032 PMID:18486119 NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18945913 NCBI chr 2:168,247,490...168,367,616
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16014726 PMID:20149346 NCBI chr 3:28,501,836...28,528,754
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO protein:decreased expression:prefrontal cortex (human) RGD PMID:23727505 RGD:13792719 NCBI chr 1:211,010,259...211,031,013
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Grk3 G protein-coupled receptor kinase 3 ISO protein:decreased expression:prefrontal cortex (human) RGD PMID:23727505 RGD:13792719 NCBI chr12:49,285,228...49,395,803
Ensembl chr12:43,624,897...43,731,262 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 ISO protein:decreased expression:prefrontal cortex (human) RGD PMID:23727505 RGD:13792719 NCBI chr 1:270,014,314...270,208,294
Ensembl chr 1:260,028,242...260,218,701 		JBrowse link
G Grm2 glutamate metabotropic receptor 2 IMP knockout compared to wild type RGD PMID:28700935 RGD:38501064 NCBI chr 8:116,158,810...116,171,857
Ensembl chr 8:107,280,099...107,293,146 		JBrowse link
G Grm2em1 glutamate metabotropic receptor 2; endonuclease induced mutant 1 IMP KO compared to wild-type rats RGD PMID:28700935 RGD:38501064
G Grm5 glutamate metabotropic receptor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20826661 NCBI chr 1:150,722,711...151,297,585
Ensembl chr 1:141,312,368...141,882,274 		JBrowse link
G Hcrt hypocretin neuropeptide precursor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16357203 NCBI chr10:86,190,289...86,191,524
Ensembl chr10:85,689,465...85,691,210 		JBrowse link
G Hcrtr1 hypocretin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16357203 PMID:19591850 PMID:19741128 NCBI chr 5:147,761,392...147,771,846
Ensembl chr 5:142,477,214...142,486,674 		JBrowse link
G Hdac4 histone deacetylase 4 ISO CTD Direct Evidence: therapeutic CTD PMID:17988634 NCBI chr 9:99,950,972...100,200,994
Ensembl chr 9:92,507,611...92,750,164 		JBrowse link
G Hdac5 histone deacetylase 5 ISO CTD Direct Evidence: therapeutic CTD PMID:17988634 NCBI chr10:87,653,139...87,688,078
Ensembl chr10:87,152,978...87,188,235 		JBrowse link
G Homer1 homer scaffold protein 1 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:16160706 PMID:16314758 NCBI chr 2:26,279,012...26,388,279
Ensembl chr 2:24,543,093...24,644,785 		JBrowse link
G Homer2 homer scaffold protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15545022 NCBI chr 1:144,968,207...145,069,022
Ensembl chr 1:135,567,414...135,659,772 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:11853856 NCBI chr 2:38,427,169...38,431,733
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:9603521 PMID:17509084 NCBI chr 8:91,395,405...91,414,815
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Cocaine-Related Disorders		 CTD
ClinVar		 PMID:9635956 PMID:11259563 PMID:12476319 PMID:15364038 PMID:16300424 More... NCBI chr15:56,360,647...56,428,703
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr3b 5-hydroxytryptamine receptor 3B susceptibility ISO DNA:SNP:cds:rs1176744(human) RGD PMID:20838391 RGD:6480660 NCBI chr 8:58,175,785...58,204,939
Ensembl chr 8:49,279,173...49,308,444 		JBrowse link
G Ice2 interactor of little elongation complex ELL subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438686 NCBI chr 8:78,921,962...78,965,983
Ensembl chr 8:70,043,424...70,084,995 		JBrowse link
G Ilk integrin-linked kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18702665 PMID:19629758 NCBI chr 1:169,500,716...169,506,972
Ensembl chr 1:160,088,897...160,095,140 		JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: therapeutic CTD PMID:17898221 NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,734,122...18,735,799 		JBrowse link
G Klhl5 kelch-like family member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438686 NCBI chr14:43,497,915...43,565,833
Ensembl chr14:43,144,257...43,184,238 		JBrowse link
G Lhb luteinizing hormone subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:12893845 NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972 		JBrowse link
G Lrrc7 leucine rich repeat containing 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438686 NCBI chr 2:249,792,441...250,294,267
Ensembl chr 2:247,147,752...247,634,547 		JBrowse link
G Manea mannosidase, endo-alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438686 PMID:19255376 NCBI chr 5:44,992,937...45,015,084
Ensembl chr 5:40,196,396...40,218,459 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16407894 PMID:20692647 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20692647 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mecp2 methyl CpG binding protein 2 treatment ISO
IMP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20711185 PMID:20711185 RGD:12789445 NCBI chr  X:156,932,481...156,995,981
Ensembl chr  X:151,789,930...151,844,689 		JBrowse link
G Mir130a microRNA 130a ISO CTD Direct Evidence: marker/mechanism CTD PMID:20643829 NCBI chr 3:90,229,228...90,229,315
Ensembl chr 3:69,822,542...69,822,629 		JBrowse link
G Mir136 microRNA 136 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20643829 NCBI chr 6:134,331,335...134,331,416
Ensembl chr 6:128,549,096...128,549,177 		JBrowse link
G Mir137 microRNA 137 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20643829 NCBI chr 2:209,165,709...209,165,810
Ensembl chr 2:206,480,884...206,480,985 		JBrowse link
G Mir138-1 microRNA 138-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20643829 NCBI chr 8:131,178,434...131,178,532
Ensembl chr 8:122,300,966...122,301,064 		JBrowse link
G Mir148b microRNA 148b ISO CTD Direct Evidence: marker/mechanism CTD PMID:20643829 NCBI chr 7:136,299,870...136,299,966
Ensembl chr 7:134,421,398...134,421,494 		JBrowse link
G Mir154 microRNA 154 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20643829 NCBI chr 6:134,574,352...134,574,435
Ensembl chr 6:128,752,947...128,753,030 		JBrowse link
G Mir186 microRNA 186 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20643829 NCBI chr 2:249,241,650...249,241,735
Ensembl chr 2:246,582,806...246,582,891 		JBrowse link
G Mir212 microRNA 212 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20613834 PMID:20711185 NCBI chr10:60,521,740...60,521,850
Ensembl chr10:60,023,403...60,023,513 		JBrowse link
G Mir301b microRNA 301b ISO CTD Direct Evidence: marker/mechanism CTD PMID:20643829 NCBI chr11:97,384,033...97,384,110
Ensembl chr11:83,879,816...83,879,893 		JBrowse link
G Mir324 microRNA 324 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20643829 NCBI chr10:55,233,363...55,233,445
Ensembl chr10:54,734,678...54,734,766 		JBrowse link
G Mir337 microRNA 337 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20643829 NCBI chr 6:134,321,142...134,321,238
Ensembl chr 6:128,538,902...128,538,998 		JBrowse link
G Mir488 microRNA 488 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20643829 NCBI chr13:73,216,541...73,216,619
Ensembl chr13:70,683,064...70,683,142 		JBrowse link
G Mir500 microRNA 500 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20643829 NCBI chr  X:17,930,647...17,930,726
Ensembl chr  X:15,258,768...15,258,859 		JBrowse link
G Mir544 microRNA 544 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20643829 NCBI chr 6:134,564,935...134,565,012
Ensembl chr 6:128,743,530...128,743,607 		JBrowse link
G Mir665 microRNA 665 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20643829 NCBI chr 6:134,321,679...134,321,772
Ensembl chr 6:128,539,440...128,539,533 		JBrowse link
G Ngf nerve growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:17715210 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Nps neuropeptide S ISO CTD Direct Evidence: marker/mechanism CTD PMID:19339610 PMID:20974945 PMID:21466221 NCBI chr 1:199,505,772...199,510,915
Ensembl chr 1:190,077,040...190,080,821 		JBrowse link
G Npsr1 neuropeptide S receptor 1 treatment IMP RGD PMID:22982682 RGD:9831202 NCBI chr 8:30,882,830...31,107,425
Ensembl chr 8:22,606,946...22,831,558 		JBrowse link
G Npy neuropeptide Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:19063928 NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
G Npy2r neuropeptide Y receptor Y2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18828811 NCBI chr 2:170,200,027...170,210,286
Ensembl chr 2:167,903,879...167,905,024 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12805318 PMID:19234455 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 susceptibility ISO DNA:SNP:intron: (rs1040288) (human) RGD PMID:24766650 RGD:401976505 NCBI chr19:47,619,853...47,964,089
Ensembl chr19:30,715,648...31,059,885 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20826313 PMID:20947769 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Oprk1 opioid receptor, kappa 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18575850 PMID:20232055 NCBI chr 5:18,657,866...18,675,671
Ensembl chr 5:13,860,021...13,877,823 		JBrowse link
G Oprm1 opioid receptor, mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12815747 PMID:16893609 PMID:18762918 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Pdyn prodynorphin ISO
IEP
IMP		 CTD Direct Evidence: marker/mechanism
mRNA:altered expression:brain
DNA:VNTR:promoter		 CTD
RGD		 PMID:16184603 PMID:17559549 PMID:18575850 PMID:18923396 PMID:8840025 More... RGD:401851906, RGD:401850568, RGD:401850567 NCBI chr 3:137,354,161...137,366,503
Ensembl chr 3:116,900,992...116,913,334 		JBrowse link
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:11750770 PMID:16520439 PMID:18201294 PMID:19279569 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Prl prolactin ISO CTD Direct Evidence: marker/mechanism CTD PMID:15064918 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Prmt6 protein arginine methyltransferase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27506785 NCBI chr 2:200,615,780...200,620,790
Ensembl chr 2:197,927,220...197,933,648 		JBrowse link
G Rhoa ras homolog family member A ISO CTD Direct Evidence: marker/mechanism CTD PMID:30158054 NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Rps6ka5 ribosomal protein S6 kinase A5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16339038 NCBI chr 6:125,558,434...125,736,576
Ensembl chr 6:119,828,846...120,006,224 		JBrowse link
G Runx2 RUNX family transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30158054 NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr12:36,957,302...37,023,982
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
G Sigmar1 sigma non-opioid intracellular receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12736327 PMID:16132061 NCBI chr 5:61,700,021...61,702,799
Ensembl chr 5:56,904,159...56,907,017 		JBrowse link
G Slc1a2 solute carrier family 1 member 2 ISO CTD Direct Evidence: therapeutic CTD PMID:19625514 NCBI chr 3:109,460,109...109,590,445
Ensembl chr 3:89,005,129...89,126,498 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:11320258 PMID:11746736 PMID:16537431 PMID:19602552 NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 susceptibility ISO protein:decreased activity: :
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:11320258 PMID:20838391 RGD:6480660 NCBI chr10:62,322,688...62,357,060
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Smad1 SMAD family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30158054 NCBI chr19:45,417,430...45,477,962
Ensembl chr19:28,513,131...28,573,651 		JBrowse link
G Smad3 SMAD family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27422367 NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smad5 SMAD family member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30158054 NCBI chr17:7,867,640...7,896,983
Ensembl chr17:7,864,720...7,891,634 		JBrowse link
G Smarca4 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27422367 NCBI chr 8:28,438,370...28,535,071
Ensembl chr 8:20,167,717...20,258,975 		JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30158054 NCBI chr12:14,748,717...14,840,273
Ensembl chr12:9,635,025...9,726,519 		JBrowse link
G Snca synuclein alpha ISO mRNA,protein:increased expression:dopamine neuron
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:18055133 PMID:12684441 RGD:6480198 NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Sncg synuclein, gamma IMP RGD PMID:20579003 RGD:6218958 NCBI chr16:9,706,765...9,712,072
Ensembl chr16:9,700,514...9,705,368 		JBrowse link
G Srcin1 SRC kinase signaling inhibitor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:27506785 NCBI chr10:82,999,295...83,066,359
Ensembl chr10:82,504,393...82,571,040 		JBrowse link
G Syt13 synaptotagmin 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438686 NCBI chr 3:99,332,554...99,372,960
Ensembl chr 3:78,877,114...78,917,392 		JBrowse link
G Tacr3 tachykinin receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18422838 NCBI chr 2:225,940,497...226,037,756
Ensembl chr 2:223,266,536...223,363,791 		JBrowse link
G Tenm3 teneurin transmembrane protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438686 NCBI chr16:47,984,732...50,711,352
Ensembl chr16:41,252,182...43,978,594 		JBrowse link
G Tyk2 tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438686 NCBI chr 8:27,918,054...27,943,319
Ensembl chr 8:19,641,884...19,667,044 		JBrowse link
drug dependence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A treatment ISO DNA:polymorphisms: :2677G>T, ���1236C>T (human) RGD PMID:24455721 RGD:401901193 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Ache acetylcholinesterase susceptibility ISO DNA:SNP:3'UTR:rs17228602 (human) RGD PMID:31129131 RGD:405855848 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Ankk1 ankyrin repeat and kinase domain containing 1 ISO associated with alcohol dependence;DNA:haplotype:exons: RGD PMID:18828801 RGD:401959320 NCBI chr 8:58,676,327...58,685,012
Ensembl chr 8:49,779,862...49,788,024 		JBrowse link
G Comt catechol-O-methyltransferase susceptibility ISO associated with Trauma and Stressor Related Disorders;DNA:polymorphism:exon: p.V158M (human) RGD PMID:31150143 RGD:401940120 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 treatment IEP ketamine RGD PMID:29476799 RGD:401938642 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 treatment ISO DNA:polymorphism: :785A>G (rs2279343), (human) RGD PMID:24455721 RGD:401901193 NCBI chr 1:90,780,468...90,859,852
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Faah fatty acid amide hydrolase ISO ClinVar Annotator: match by term: Drug addiction, susceptibility to ClinVar PMID:12060782 PMID:15254019 PMID:16972078 PMID:23556448 PMID:25741868 NCBI chr 5:134,716,545...134,735,396
Ensembl chr 5:129,479,824...129,498,677 		JBrowse link
G Ncam1 neural cell adhesion molecule 1 ISO associated with alcohol dependence;DNA:haplotype:exon: RGD PMID:18828801 RGD:401959320 NCBI chr 8:58,762,088...59,062,131
Ensembl chr 8:49,865,633...50,166,014 		JBrowse link
G Oprm1 opioid receptor, mu 1 ISO DNA:SNP, haplotype:exon 1 (rs1799971) (human) RGD PMID:33402148 RGD:402528879 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Ttc12 tetratricopeptide repeat domain 12 ISO associated with alcohol dependence;DNA:haplotype:exon: RGD PMID:18828801 RGD:401959320 NCBI chr 8:58,696,381...58,743,857
Ensembl chr 8:49,799,920...49,847,087 		JBrowse link
Drug Overdose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A susceptibility ISO DNA:SNPs:exons :3435C>T (rs1045642), 1236C>T (rs1128503)(human) RGD PMID:23515680 RGD:401901187 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Agt angiotensinogen ISO CTD Direct Evidence: therapeutic CTD PMID:8527259 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Avp arginine vasopressin ISO CTD Direct Evidence: therapeutic CTD PMID:11914425 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 susceptibility ISO DNA:SNPs:cds:rs3745274 (c.516G > T, Q172H), rs8192719 (21563 C > T) (human) RGD PMID:28184434 RGD:401901144 NCBI chr 1:90,780,468...90,859,852
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 susceptibility ISO DNA:polymorphism: :CYP2D6*4(1846G>A)(human) RGD PMID:15349706 RGD:401901260 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
drug psychosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 IEP protein:increased expression:striatum RGD PMID:26174132 RGD:11534754 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Drd2 dopamine receptor D2 IEP RGD PMID:26174132 RGD:11534754 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Gad1 glutamate decarboxylase 1 susceptibility ISO
IEP		 associated with amphetamine abuse; DNA:haplotype: :rs769404���rs701492(human)
protein:decreased expression:prefrontal cortex 		RGD PMID:27967329 PMID:24200867 RGD:401900122, RGD:401900162 NCBI chr 3:75,777,260...75,818,099
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gad2 glutamate decarboxylase 2 susceptibility ISO associated with amphetamine abuse; DNA:SNP: :rs2236418(human) RGD PMID:27967329 RGD:401900122 NCBI chr17:89,671,718...89,734,246
Ensembl chr17:84,763,628...84,826,155 		JBrowse link
G Oprm1 opioid receptor, mu 1 ISO associated with amphetamine abuse;DNA:SNP:intron:IVS2+691G>C (human) RGD PMID:16402083 RGD:401827939 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
fetal alcohol spectrum disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank3 ankyrin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29109170 NCBI chr20:18,601,307...19,224,790
Ensembl chr20:18,602,786...19,086,300 		JBrowse link
G Apoe apolipoprotein E ISO RGD PMID:15007105 RGD:12904641 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Avp arginine vasopressin IEP mRNA:decreased expression:hypothalamic nucleus RGD PMID:15142835 RGD:596933086 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Bpifa1 BPI fold containing family A, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15513904 NCBI chr 3:163,087,965...163,093,708
Ensembl chr 3:142,627,810...142,633,552 		JBrowse link
G C3 complement C3 IEP protein:increased activity:blood RGD PMID:30657461 RGD:408418720 NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G C5 complement C5 IEP protein:increased activity:blood RGD PMID:30657461 RGD:408418720 NCBI chr 3:38,668,174...38,759,468
Ensembl chr 3:18,270,696...18,361,994 		JBrowse link
G Cat catalase ISO CTD Direct Evidence: therapeutic CTD PMID:26074427 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 sexual_dimorphism IEP associated with chronic mild stress, age effect; mRNA:altered expression:hippocampus (rat) RGD PMID:29251811 RGD:401965484 NCBI chr10:89,540,192...89,583,466
Ensembl chr10:89,040,203...89,083,481 		JBrowse link
G Dio3 iodothyronine deiodinase 3 treatment IEP RGD PMID:23763370 RGD:13432044 NCBI chr 6:135,107,072...135,108,933
Ensembl chr 6:129,285,749...129,286,660 		JBrowse link
G Dnmt1 DNA methyltransferase 1 IEP mRNA,protein:increased expression:Pituitary gland (rat) RGD PMID:26509893 RGD:11344152 NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta IEP mRNA:increased expression:pituitary gland (rat) RGD PMID:26509893 RGD:11344152 NCBI chr 3:162,590,777...162,629,313
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G Drd2 dopamine receptor D2 IDA
IEP		 DNA:Hypermethylation:promoter
mRNA:decreased expression: pituitary gland (rat)		 RGD PMID:26509893 PMID:28710248 RGD:11344152, RGD:401960105 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 IEP mRNA:increased expression:pituitary gland (rat) RGD PMID:26509893 RGD:11344152 NCBI chr20:3,924,263...3,941,238
Ensembl chr20:3,919,624...3,941,547 		JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 treatment
sexual_dimorphism		 IEP
ISO		 in male mice only; mRNA:increased expression:frontal cortex: RGD PMID:23763370 PMID:30312858 RGD:13432044, RGD:405866345 NCBI chr 1:117,602,772...117,838,230
Ensembl chr 1:108,296,124...108,698,961 		JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 IEP mRNA:increased expression:posterior hypothalamic region (rat) RGD PMID:18514412 RGD:402528884 NCBI chr10:26,876,926...26,965,523
Ensembl chr10:26,374,694...26,464,346 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B treatment IMP
IEP		 RGD PMID:22037411 PMID:23763370 RGD:13210751, RGD:13432044 NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Hdac2 histone deacetylase 2 IEP mRNA,protein:increased expression:pituitary gland (rat) RGD PMID:26509893 RGD:11344152 NCBI chr20:42,101,815...42,126,486
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Hdac4 histone deacetylase 4 IEP mRNA,protein:increased expression:pituitary gland (rat) RGD PMID:26509893 RGD:11344152 NCBI chr 9:99,950,972...100,200,994
Ensembl chr 9:92,507,611...92,750,164 		JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 IEP protein:increased expression:placenta (rat) RGD PMID:26342748 RGD:401965481 NCBI chr19:50,307,569...50,312,812
Ensembl chr19:33,397,656...33,402,899 		JBrowse link
G Igf1 insulin-like growth factor 1 IEP mRNA:decreased expression:cerebellum (rat) RGD PMID:16909201 RGD:12904886 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor IEP protein:decreased activity:cerebellum (rat) RGD PMID:16909201 RGD:12904886 NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Mat2a methionine adenosyltransferase 2A IEP mRNA:decreased expression:brain (rat) RGD PMID:26180184 RGD:11074449 NCBI chr 4:106,048,043...106,053,612
Ensembl chr 4:104,488,466...104,495,493 		JBrowse link
G Mecp2 methyl CpG binding protein 2 treatment IEP mRNA:increased expression:pituitary gland (rat) RGD PMID:26509893 PMID:23763370 RGD:11344152, RGD:13432044 NCBI chr  X:156,932,481...156,995,981
Ensembl chr  X:151,789,930...151,844,689 		JBrowse link
G Mir326 microRNA 326 IEP miRNA:increases expression:pituitary gland (rat) RGD PMID:28710248 RGD:401960105 NCBI chr 1:163,266,165...163,266,259
Ensembl chr 1:153,854,029...153,854,123 		JBrowse link
G Mir9 microRNA 9 IEP miRNA:increased expression:pituitary gland (rat) RGD PMID:28710248 RGD:401960105 NCBI chr 9:1,167,436...1,167,545
Ensembl chr 9:1,080,274...1,080,383 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase IEP mRNA:decreased expression:brain (rat) RGD PMID:26180184 RGD:11074449 NCBI chr17:62,911,705...62,996,544
Ensembl chr17:58,220,071...58,304,822 		JBrowse link
G Nos1 nitric oxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25511929 NCBI chr12:44,276,011...44,456,371
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 sexual_dimorphism IEP associated with chronic mild stress, age effect; mRNA:altered expression:hippocampus (rat) RGD PMID:29251811 RGD:401965484 NCBI chr19:47,619,853...47,964,089
Ensembl chr19:30,715,648...31,059,885 		JBrowse link
G Oprk1 opioid receptor, kappa 1 IEP DNA, mRNA:hypomethylation, increased expression:ventral tegmental area, prefrontal cortex RGD PMID:29678771 RGD:401851055 NCBI chr 5:18,657,866...18,675,671
Ensembl chr 5:13,860,021...13,877,823 		JBrowse link
G Oprl1 opioid related nociceptin receptor 1 IEP mRNA:decreased expression:ventral tegmental area RGD PMID:29678771 RGD:401851055 NCBI chr 3:189,209,495...189,225,406
Ensembl chr 3:168,834,003...168,839,920 		JBrowse link
G Pdyn prodynorphin IEP DNA, mRNA:hypomethylation, altered expression:ventral tegmental area, nucleus accumbens RGD PMID:29678771 RGD:401851055 NCBI chr 3:137,354,161...137,366,503
Ensembl chr 3:116,900,992...116,913,334 		JBrowse link
G Per2 period circadian regulator 2 treatment ISO RGD PMID:31329297 RGD:405878078 NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:92,007,296...92,049,459 		JBrowse link
G Pnoc prepronociceptin IEP mRNA:increased expression:nucleus accumbens RGD PMID:29678771 RGD:401851055 NCBI chr15:43,800,240...43,827,841
Ensembl chr15:39,624,641...39,651,867 		JBrowse link
G Pomc proopiomelanocortin treatment ISO RGD PMID:31329297 RGD:405878078 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Prl prolactin IEP mRNA,protein:increased expression:pituitary gland, blood plasma (rat)
mRNA, protein:increased expression:pituitary gland, blood plasma (rat)		 RGD PMID:26509893 PMID:28710248 RGD:11344152, RGD:401960105 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Pten phosphatase and tensin homolog IEP Protein:increased expression, increased activity:cerebellum (rat) RGD PMID:12700235 RGD:12801493 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 treatment IEP RGD PMID:23763370 RGD:13432044 NCBI chr 8:99,324,986...99,454,099
Ensembl chr 8:90,445,154...90,574,269 		JBrowse link
G Rps6ka1 ribosomal protein S6 kinase A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29109170 NCBI chr 5:151,362,819...151,402,064
Ensembl chr 5:146,079,021...146,118,272 		JBrowse link
G Setd7 SET domain containing 7, histone lysine methyltransferase IEP mRNA:decreased expression:pituitary gland (rat) RGD PMID:26509893 RGD:11344152 NCBI chr 2:137,713,545...137,756,319
Ensembl chr 2:135,562,683...135,605,468 		JBrowse link
G Slc25a12 solute carrier family 25 member 12 treatment IEP RGD PMID:23763370 RGD:13432044 NCBI chr 3:76,504,868...76,599,536
Ensembl chr 3:56,097,269...56,192,100 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 IEP mRNA:decreased expression:brain (rat) RGD PMID:26180184 RGD:11074449 NCBI chr10:62,322,688...62,357,060
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Tlr4 toll-like receptor 4 ameliorates ISO RGD PMID:30312858 RGD:405866345 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Ube3a ubiquitin protein ligase E3A treatment IEP RGD PMID:23763370 RGD:13432044 NCBI chr 1:119,204,244...119,297,097
Ensembl chr 1:110,070,480...110,157,250 		JBrowse link
fetal alcohol syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rhoa ras homolog family member A IEP protein:increased activation:neuron, cerebellum RGD PMID:17109064 RGD:2298867 NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
heroin dependence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IMP RGD PMID:10900239 RGD:10046064 NCBI chr10:7,503,351...7,599,474
Ensembl chr10:6,999,819...7,092,835 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A treatment ISO associated with methadone treatment;DNA:SNP:intron (rs1128503) (human) RGD PMID:29173032 RGD:401976557 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Ache acetylcholinesterase ISO protein:increased activity:blood RGD PMID:31129131 RGD:405855848 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:15717844 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Adra1a adrenoceptor alpha 1A susceptibility ISO DNA:SNP:exon 4: p.R347C (rs1048101) (human) RGD PMID:33577997 RGD:401940110 NCBI chr15:45,005,648...45,111,416
Ensembl chr15:40,832,534...40,927,500 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 ameliorates IMP RGD PMID:33619816 RGD:408346756 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member susceptibility ISO DNA:polymorphism: : RGD PMID:21723677 RGD:401959204 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Ankk1 ankyrin repeat and kinase domain containing 1 onset
susceptibility		 ISO DNA:SNPS:exon:rs17115439, rs7118900, rs1800497 (human)
DNA:SNPs:5'UTR,exon:rs877138, rs4938013(human)
DNA:SNP:exon:rs1800497(human)
DNA:SNPs, haplotypes:intron, 3'flanking:rs11214598, rs2859545(human)		 RGD PMID:28854834 PMID:23303482 PMID:23840506 PMID:29550268 RGD:401959202, RGD:401959304, RGD:401959223, RGD:401959205 NCBI chr 8:58,676,327...58,685,012
Ensembl chr 8:49,779,862...49,788,024 		JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 IEP protein:increased expression:medial prefrontal cortex (rat) RGD PMID:19160503 RGD:529195970 NCBI chr11:93,859,690...93,868,600
Ensembl chr11:80,328,041...80,364,140 		JBrowse link
G Arrb2 arrestin, beta 2 treatment ISO DNA:polymorphism: :rs1045280(human)
associated with methadone treatment;DNA:SNP:intron (rs1045280) (human)		 RGD PMID:33783060 PMID:29173032 RGD:401901593, RGD:401976557 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 IEP protein:decreased expression:medial prefrontal cortex (rat) RGD PMID:19160503 RGD:529195970 NCBI chr 7:35,622,267...35,731,904
Ensembl chr 7:33,735,871...33,843,295 		JBrowse link
G Bche butyrylcholinesterase ISO protein:increased activity:blood plasma (human) RGD PMID:30707402 RGD:401960085 NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Bdnf brain-derived neurotrophic factor ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:serum		 CTD
RGD		 PMID:17715210 PMID:17715210 RGD:401976440 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 ISO DNA:SNP:intron:rs2350780 (human) RGD PMID:19500151 RGD:5509583 NCBI chr 4:65,981,136...66,116,128
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Cnr1 cannabinoid receptor 1 treatment ISO DNA:SNP: :rs806368 RGD PMID:32481444 RGD:597805904 NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Comt catechol-O-methyltransferase severity
onset
susceptibility		 ISO DNA:SNP:exon 5: (rs769224) (human)
DNA:SNP:cd: p.V158M (human)
DNA:SNP:: (rs737866) (Human)
DNA:SNP:-287A>G (human)
DNA:SNP:exon 1: (rs737866) (Human)
DNA:SNP:exon 4: (rs4680) p.V158M (human)		 RGD PMID:33577997 PMID:33544778 PMID:23155402 PMID:12476424 PMID:21857968 More... RGD:401940110, RGD:401959602, RGD:401959234, RGD:401940154, RGD:401940140, RGD:401940113 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 treatment IDA
ISO		 DNA:SNP:exon:rs35349697 RGD PMID:21362452 PMID:24704376 PMID:23062870 RGD:401901181, RGD:401938627, RGD:401901182 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Ctnnb1 catenin beta 1 IEP protein:decreased expression:medial prefrontal cortex (rat) RGD PMID:19160503 RGD:529195970 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 treatment ISO DNA:polymorphisms: :785A>G (rs2279343), 516G>T (rs3745274)(human)
DNA:SNP: :rs16974799		 RGD PMID:21790905 PMID:32481444 RGD:11097675, RGD:597805904 NCBI chr 1:90,780,468...90,859,852
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 treatment ISO DNA:SNP:exon:CYP2C19*2 (681G>A,rs4244285)(human)
DNA:SNPs::CYP2C19*2, CYP2C19*3(human)		 RGD PMID:24016178 PMID:24956251 RGD:401960868, RGD:401960881 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Drd1 dopamine receptor D1 IEP RGD PMID:28598964 RGD:13506959 NCBI chr17:10,545,488...10,550,029
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 susceptibility
onset		 ISO
IEP		 CTD Direct Evidence: marker/mechanism
DNA:SNP:intron:rs1079597(human)
DNA:SNPS:exon, intron:multiples(human)		 CTD
RGD		 PMID:11751029 PMID:23840506 PMID:28854834 PMID:28598964 RGD:401959223, RGD:401959202, RGD:13506959 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 IEP RGD PMID:28598964 RGD:13506959 NCBI chr11:70,385,586...70,437,793
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Drd4 dopamine receptor D4 susceptibility
onset		 ISO DNA:SNPs:5promoter:rs1800955,rs936462(human)
DNA:SNP,methylation::rs3758653(human)
DNA:polymorphism:promoter:-521G>A(human)		 RGD PMID:23840506 PMID:34864042 PMID:18991844 RGD:401959223, RGD:401959595, RGD:401959594 NCBI chr 1:205,825,937...205,829,124
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Fas Fas cell surface death receptor IEP protein:increased expression:cerebral cortex (rat) RGD PMID:14530904 RGD:8686423 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 susceptibility ISO DNA:SNPs:intron,3'utr: (rs1360780,rs3800373) (human) RGD PMID:24845178 RGD:401976498 NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,457,216...6,541,674 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit ameliorates
treatment		 IDA
IEP		 RGD PMID:21362452 PMID:17165513 PMID:23062870 RGD:401901181, RGD:407571685, RGD:401901182 NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 susceptibility ISO DNA:SNP:intron: C>G (rs29220) (human) RGD PMID:26727527 RGD:11552767 NCBI chr20:1,469,779...1,499,352
Ensembl chr20:1,464,534...1,493,994 		JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19833324 NCBI chr14:37,451,218...37,587,458
Ensembl chr14:37,097,279...37,228,944 		JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 susceptibility ISO DNA:SNP:promoter:rs4906902(human)
DNA:SNP::rs7165224(human)		 RGD PMID:25025424 PMID:19500151 RGD:405866341, RGD:5509583 NCBI chr 1:117,602,772...117,838,230
Ensembl chr 1:108,296,124...108,698,961 		JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 ISO DNA:SNP:intron: (rs211014) (human) RGD PMID:17440936 RGD:402525444 NCBI chr10:26,876,926...26,965,523
Ensembl chr10:26,374,694...26,464,346 		JBrowse link
G Gad1 glutamate decarboxylase 1 treatment
susceptibility		 ISO DNA:SNPs, haplotype:multiple:
DNA:SNP,haplotype: :rs2058725(human)
DNA:SNPs,haplotypes:promoter,exon:rs1978340, rs3791878, rs11542313 (human)		 RGD PMID:31866536 PMID:19500151 PMID:22564729 RGD:401900128, RGD:5509583, RGD:401900156 NCBI chr 3:75,777,260...75,818,099
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gad2 glutamate decarboxylase 2 susceptibility ISO DNA:SNP: ::rs8190646(human) RGD PMID:19500151 RGD:5509583 NCBI chr17:89,671,718...89,734,246
Ensembl chr17:84,763,628...84,826,155 		JBrowse link
G Gdnf glial cell derived neurotrophic factor ISO DNA:SNP: :rs2910709 RGD PMID:24022000 RGD:405849398 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 treatment ISO
IEP		 mRNA:increased expression:ventral striatum (human) RGD PMID:27863698 PMID:19940171 RGD:405096665, RGD:4107717 NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 IEP protein:decreased expression:medial prefrontal cortex (rat)
protein:decreased expression:infralimbic area synaptosome (rat)		 RGD PMID:19160503 PMID:29134962 RGD:529195970, RGD:596920311 NCBI chr 2:168,247,490...168,367,616
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 IEP protein:decreased expression:medial prefrontal cortex (rat) RGD PMID:19160503 RGD:529195970 NCBI chr  X:125,103,975...125,369,690
Ensembl chr  X:120,238,534...120,504,096 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A susceptibility ISO DNA:repeats,SNPs,haplotype:introns:(GT)26, rs3219790,rs1102972,rs1650420,rs3104703 (human)
DNA:repeats: :(GT)26 (human)		 RGD PMID:23940648 PMID:25366762 RGD:401938628, RGD:401938629 NCBI chr10:6,136,458...6,560,003
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B IEP protein:decreased expression:medial prefrontal cortex (rat) RGD PMID:19160503 RGD:529195970 NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Grm2 glutamate metabotropic receptor 2 IMP RGD PMID:30283001 RGD:38501063 NCBI chr 8:116,158,810...116,171,857
Ensembl chr 8:107,280,099...107,293,146 		JBrowse link
G Grm2em1 glutamate metabotropic receptor 2; endonuclease induced mutant 1 IMP KO compared to wild-type rats RGD PMID:30283001 RGD:38501063
G Hcrt hypocretin neuropeptide precursor treatment ISO RGD PMID:35984180 RGD:401960075 NCBI chr10:86,190,289...86,191,524
Ensembl chr10:85,689,465...85,691,210 		JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A ISO DSNA:SNPs:promoter, intron, CDS:g.113974819C>T, g.113985089A>G, g.113989703A>G (rs1150226, rs897687, rs1176713) (human)
DNA:SNPs, haplotype:multiple (human)		 RGD PMID:26227246 PMID:19500151 RGD:405096480, RGD:5509583 NCBI chr 8:58,138,514...58,150,960
Ensembl chr 8:49,242,020...49,254,389 		JBrowse link
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 ISO DNA:SNP: :rs2070995 (human) RGD PMID:20220551 RGD:6483055 NCBI chr11:47,531,312...47,778,348
Ensembl chr11:34,061,708...34,308,758 		JBrowse link
G Lep leptin ISO CTD Direct Evidence: marker/mechanism CTD PMID:15717844 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Ngf nerve growth factor treatment ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:serum
DNA:SNP:intron:rs2239622		 CTD
RGD		 PMID:17715210 PMID:17715210 PMID:21358750 RGD:401976440, RGD:401965390 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 susceptibility ISO DNA:SNP, haplotype:intron: (rs4234955) (human)
DNA:SNP:intron: (rs4518200) (human)		 RGD PMID:29465008 PMID:24845178 RGD:402463944, RGD:401976498 NCBI chr16:27,804,416...27,814,070
Ensembl chr16:23,037,789...23,046,759 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 susceptibility ISO DNA:SNP, haplotype: :rs10482672 RGD PMID:29465008 RGD:402463944 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 treatment ISO DNA:SNPs: :multiple RGD PMID:23651024 RGD:401938595 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Oprd1 opioid receptor, delta 1 onset
treatment		 ISO DNA:SNP: :rs508448 (human)
associated with stress-related disorder;DNA:SNP:coding synonymous,intron (rs2234918, rs2236857) (human)
associated with methadone treatment;DNA:SNP:intron (rs529520) (human)
DNA:SNP, haplotype:intron 1 (multiple) (human)
DNA:SNP, haplotype:multiple (multiple) (human)
DNA:SNP:CDS:intron 1 (rs204047|rs797397) (human)		 RGD PMID:28692418 PMID:30171993 PMID:29173032 PMID:22500942 PMID:34031368 More... RGD:401831045, RGD:401977579, RGD:401976557, RGD:401976535, RGD:401976533, RGD:401976443 NCBI chr 5:149,590,244...149,624,999
Ensembl chr 5:144,306,188...144,340,960 		JBrowse link
G Oprk1 opioid receptor, kappa 1 treatment IMP
ISO		 DNA:SNP: :rs3802279, rs3802281, and rs963549 (human) RGD PMID:24725195 PMID:24305833 PMID:31940240 RGD:9831447, RGD:401850592, RGD:401827951 NCBI chr 5:18,657,866...18,675,671
Ensembl chr 5:13,860,021...13,877,823 		JBrowse link
G Oprl1 opioid related nociceptin receptor 1 treatment ISO DNA:SNP: :rs2229205 RGD PMID:32481444 RGD:597805904 NCBI chr 3:189,209,495...189,225,406
Ensembl chr 3:168,834,003...168,839,920 		JBrowse link
G Oprm1 opioid receptor, mu 1 susceptibility
no_association
severity		 ISO CTD Direct Evidence: marker/mechanism
mRNA:splice variants:prefrontal cortex
DNA:SNPs, haplotypes: :multiple
DNA:missense mutation:exon:p.N40D (118A>G) (rs 1799971) (human)
DNA:SNP, haplotype: :rs483481 (human)
DNA:SNPs, haplotypes: :rs696522, rs1381376, rs3778151 (human)		 CTD
RGD		 PMID:20201854 PMID:32506472 PMID:28692418 PMID:28976288 PMID:11424981 More... RGD:401831047, RGD:401831045, RGD:401831044, RGD:401827953, RGD:401827950, RGD:401827940 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Pdyn prodynorphin onset
susceptibility
no_association		 ISO DNA:repeat:promoter:rs35286251 (human)
DNA:VNTR, SNPs:rs1022563, rs2235749, rs910080 (human)
DNA:VNTR:promoter
DNA:SNPs, repeat:promoter:rs2281285, rs2235749, rs35286251 (human)
DNA:SNP: :rs910080 (human)
mRNA:decreased expression:periamygdaloid cortex		 RGD PMID:30936032 PMID:21382455 PMID:30138645 PMID:29911117 PMID:29911117 More... RGD:401850549, RGD:401850577, RGD:401850562, RGD:401850561, RGD:401850561, RGD:401850556, RGD:401850554 NCBI chr 3:137,354,161...137,366,503
Ensembl chr 3:116,900,992...116,913,334 		JBrowse link
G Penk proenkephalin IMP RGD PMID:22683090 RGD:10003025 NCBI chr 5:21,981,381...21,987,074
Ensembl chr 5:17,183,806...17,189,129 		JBrowse link
G Pomc proopiomelanocortin treatment ISO
IDA
IEP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:18201294 PMID:6316060 PMID:23771528 RGD:407572514, RGD:407431642 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Retn resistin ISO CTD Direct Evidence: marker/mechanism CTD PMID:15717844 NCBI chr12:6,508,653...6,511,115
Ensembl chr12:1,710,881...1,712,620 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 IEP RGD PMID:28598964 RGD:13506959 NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Th tyrosine hydroxylase onset ISO DNA:SNP:5'utr:(rs10770140) (human) RGD PMID:32736537 RGD:405866368 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Tph1 tryptophan hydroxylase 1 ISO DNA:SNP: :rs1799913 RGD PMID:18181017 RGD:597621691 NCBI chr 1:106,293,695...106,314,628
Ensembl chr 1:97,157,409...97,178,344 		JBrowse link
G Tph2 tryptophan hydroxylase 2 treatment ISO DNA:SNPs: :rs4290270, rs7963720
DNA:SNP: :rs1386493		 RGD PMID:18181017 PMID:32481444 RGD:597621691, RGD:597805904 NCBI chr 7:52,571,909...52,676,305
Ensembl chr 7:50,685,694...50,789,424 		JBrowse link
G Ttc12 tetratricopeptide repeat domain 12 susceptibility ISO DNA:SNP:5'UTR,intron:rs7130431(human) RGD PMID:23303482 RGD:401959304 NCBI chr 8:58,696,381...58,743,857
Ensembl chr 8:49,799,920...49,847,087 		JBrowse link
Inhalant Abuse term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fos Fos proto-oncogene, AP-1 transcription factor subunit IEP toluene RGD PMID:22074881 RGD:405101373 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
Intravenous Substance Abuse term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnr1 cannabinoid receptor 1 ISO RGD PMID:9106242 RGD:1358448 NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
metabolic dysfunction and alcohol associated liver disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:increased expression:plasma RGD PMID:16115302 RGD:5686674 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Adipor2 adiponectin receptor 2 treatment IEP
ISO		 RGD PMID:26115886 PMID:18755807 PMID:27220557 PMID:22013387 RGD:25330099, RGD:25824943, RGD:25824939, RGD:25440493 NCBI chr 4:154,195,440...154,261,141
Ensembl chr 4:152,524,623...152,559,355 		JBrowse link
G Adra2a adrenoceptor alpha 2A ISO protein:increased expression:liver (human) RGD PMID:30009772 RGD:401976534 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 treatment ISO RGD PMID:28987868 RGD:407574728 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member severity
treatment
susceptibility		 IDA
ISO		 human transgene in mouse model
protein:altered processing:liver (mouse)
DNA:missense mutation:cds:p.E504K (human)		 RGD PMID:17058263 PMID:25457208 PMID:29156373 PMID:29063269 RGD:1599041, RGD:15036811, RGD:15036805, RGD:14696776 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Ar androgen receptor severity IEP RGD PMID:11447013 RGD:407424619 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Arrb2 arrestin, beta 2 ameliorates ISO protein:increased expression:hepatocyte RGD PMID:33871024 PMID:33871024 RGD:401938594, RGD:401938594 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Atg7 autophagy related 7 exacerbates
ameliorates		 ISO RGD PMID:31235522 PMID:34303881 RGD:407445921, RGD:407445922 NCBI chr 4:149,390,000...149,597,534
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase IEP protein:increased expression:serum,liver RGD PMID:23083309 RGD:408425974 NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 ISO protein:increased expression:liver (human) RGD PMID:29307797 RGD:153297819 NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G C1qc complement C1q C chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:35789393 NCBI chr 5:154,410,845...154,414,208
Ensembl chr 5:149,127,415...149,131,017 		JBrowse link
G C3 complement C3 severity
ameliorates		 IEP
ISO		 RGD PMID:36653797 PMID:17321001 RGD:408395146, RGD:408418721 NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Car3 carbonic anhydrase 3 IEP mRNA,protein:decreased expression:cytosol,liver RGD PMID:23083309 RGD:408425974 NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment ISO RGD PMID:25557254 PMID:30611703 RGD:14995489, RGD:407424594 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 treatment ISO RGD PMID:25557254 RGD:14995489 NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 disease_progression ISO RGD PMID:27859576 RGD:14401742 NCBI chr 8:132,629,097...132,660,980
Ensembl chr 8:123,752,325...123,759,260 		JBrowse link
G Cd14 CD14 molecule treatment IEP RGD PMID:23277536 RGD:407424596 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G Cd36 CD36 molecule ISO RGD PMID:24280415 RGD:11041117 NCBI chr 4:18,209,088...18,302,142
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd68 Cd68 molecule treatment IEP RGD PMID:23277536 PMID:29399060 RGD:407424596, RGD:407424599 NCBI chr10:54,880,562...54,882,441
Ensembl chr10:54,381,815...54,383,697 		JBrowse link
G Crp C-reactive protein IEP protein:increased expression:serum: RGD PMID:21806828 RGD:9491781 NCBI chr13:87,694,062...87,695,978
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Ctsb cathepsin B IEP protein:increased activity:liver, cytosol (rat) RGD PMID:17850215 RGD:2315516 NCBI chr15:41,565,607...41,586,479
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 ameliorates ISO RGD PMID:33710653 RGD:401976495 NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:26428356 PMID:25583360 PMID:24064383 RGD:14700884, RGD:14700870 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO RGD PMID:22905112 RGD:9588654 NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 ameliorates ISO mRNA,protein:incrased expression:liver (human) RGD PMID:33710653 RGD:401976495 NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,457,216...6,541,674 		JBrowse link
G Foxo1 forkhead box O1 ISO protein:increased expression:liver (human) RGD PMID:30009772 RGD:401976534 NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Hamp hepcidin antimicrobial peptide IEP mRNA:decreased expression:liver RGD PMID:19253830 RGD:11041633 NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Klf5 KLF transcription factor 5 severity IEP RGD PMID:36653797 RGD:408395146 NCBI chr15:82,472,081...82,487,267
Ensembl chr15:76,064,258...76,079,445 		JBrowse link
G Lbp lipopolysaccharide binding protein treatment IEP RGD PMID:23277536 RGD:407424596 NCBI chr 3:167,373,786...167,400,941
Ensembl chr 3:146,954,015...146,981,586 		JBrowse link
G Ldlr low density lipoprotein receptor IEP protein:decreased expression: liver (rat) RGD PMID:20028367 RGD:21410185 NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Mir155 microRNA 155 ISO RGD PMID:26867493 RGD:25671474 NCBI chr11:37,261,114...37,261,178
Ensembl chr11:23,774,654...23,774,718 		JBrowse link
G Nlrc5 NLR family, CARD domain containing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36708882 NCBI chr19:10,483,601...10,587,223
Ensembl chr19:10,477,628...10,562,121 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 treatment
severity		 IMP
IEP		 RGD PMID:26256083 PMID:36653797 RGD:11522097, RGD:408395146 NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:77,158,808...77,168,722 		JBrowse link
G Ocln occludin treatment IEP RGD PMID:31116255 RGD:407424600 NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:31,657,220...31,764,150 		JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase IEP RGD PMID:17156888 RGD:1642369 NCBI chr10:45,275,434...45,349,651
Ensembl chr10:44,775,911...44,850,013 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:18703563 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit treatment IEP RGD PMID:29399060 PMID:31116255 RGD:407424599, RGD:407424600 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Ren renin severity IEP RGD PMID:36653797 RGD:408395146 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:44,796,091...44,807,489 		JBrowse link
G Serpine1 serpin family E member 1 IEP mRNA:increased expression:liver (rat) RGD PMID:25561792 RGD:11075083 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Serpinf1 serpin family F member 1 IEP protein:decreased expression:liver RGD PMID:18996124 RGD:2312349 NCBI chr10:60,748,504...60,760,898
Ensembl chr10:60,249,708...60,262,646 		JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19951287 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 IEP RGD PMID:11477087 RGD:1625694 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 IEP RGD PMID:18296740 RGD:7207884 NCBI chr 9:56,964,617...57,080,523
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Tead1 TEA domain transcription factor 1 ameliorates ISO RGD PMID:33710653 RGD:401976495 NCBI chr 1:176,227,175...176,445,122
Ensembl chr 1:166,792,628...167,003,369 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 treatment IEP RGD PMID:29399060 RGD:407424599 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tjp1 tight junction protein 1 treatment IEP RGD PMID:23277536 RGD:407424596 NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:118,849,838...119,094,432 		JBrowse link
G Tlr2 toll-like receptor 2 treatment IEP RGD PMID:23277536 RGD:407424596 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr4 toll-like receptor 4 severity
treatment		 ISO
IEP		 RGD PMID:29884546 PMID:23277536 PMID:21463341 RGD:14697697, RGD:407424596, RGD:14700554 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor susceptibility
treatment		 ISO
IEP		 DNA:SNP:promoter:-238G>A (human) RGD PMID:9214463 PMID:29399060 PMID:20143470 RGD:14995434, RGD:407424599, RGD:38508901 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Ubd ubiquitin D ISO protein:increased expression:liver (human) RGD PMID:30009772 RGD:401976534 NCBI chr20:1,390,734...1,392,685
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639 		JBrowse link
morphine dependence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A IEP mRNA:increases expression:cerebral cortex (rat) RGD PMID:9105684 RGD:401976538 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Ago2 argonaute RISC catalytic component 2 IEP RGD PMID:23927484 RGD:401900655 NCBI chr 7:106,907,209...106,994,124
Ensembl chr 7:105,029,120...105,104,974 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein ameliorates IMP RGD PMID:21549764 PMID:25746394 RGD:401851922, RGD:11087075 NCBI chr 7:108,444,959...108,448,413
Ensembl chr 7:106,555,785...106,559,378 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IDA RGD PMID:24906198 RGD:10054248 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP RGD PMID:24906198 RGD:10054248 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bdnf brain-derived neurotrophic factor treatment ISO
IEP		 mRNA:increased expression:hippocampus
protein:decreased expression:nucleus accumbens		 RGD PMID:27461790 PMID:32323150 PMID:21872672 PMID:32860885 PMID:28940732 More... RGD:401940145, RGD:596936415, RGD:596936244, RGD:596936242, RGD:596936232, RGD:401959372 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Cartpt CART prepropeptide IEP mRNA, protein:decreased expression:nucleus accumbens RGD PMID:26955782 RGD:597805883 NCBI chr 2:32,989,215...32,991,794
Ensembl chr 2:31,255,098...31,290,713 		JBrowse link
G Cnr1 cannabinoid receptor 1 treatment ISO RGD PMID:27461790 RGD:401940145 NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Comt catechol-O-methyltransferase susceptibility ISO DNA:SNP:cd: (rs4680) p.V158M (human) RGD PMID:30211780 RGD:401940137 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 treatment ISO
IEP
IDA		 CTD Direct Evidence: marker/mechanism
associated with alcohol dependence; protein:decreased phosphorylation:prefrontal cortex (rat)
protein:increased expression:neuron, brain
protein:increased phosphorylation:central amygdaloid nucleus
protein:increased phosphorylation:hypothalamus, ventral tegmental area
mRNA, protein:increased expression:hippocampus, prefrontal cortex		 CTD
RGD		 PMID:11717377 PMID:19324071 PMID:27053349 PMID:29024786 PMID:19108758 More... RGD:401901600, RGD:401959748, RGD:401959607, RGD:401959375, RGD:401959374, RGD:401950487, RGD:401940184, RGD:401940182, RGD:401940145, RGD:401940122, RGD:401940121, RGD:401940119 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Dbi diazepam binding inhibitor IEP mRNA:increased expression:brain (rat) RGD PMID:15950760 RGD:408361840 NCBI chr13:33,794,231...33,802,632
Ensembl chr13:31,206,988...31,268,693 		JBrowse link
G Drd2 dopamine receptor D2 IEP protein:decreased expression:hippocampus (rat) RGD PMID:18276072 RGD:2311587 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Fadd Fas associated via death domain severity IDA RGD PMID:21088039 RGD:11341805 NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit treatment IDA
IEP
IMP		 RGD PMID:27053349 PMID:12225868 PMID:10998122 RGD:401959748, RGD:405255651, RGD:405100721 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit ameliorates
treatment		 IEP
ISO
IDA		 protein:increased expression:brain (rat)
associated with alcohol dependence; protein:increased expression:nucleus accumbens, caudate-putamen (rat)
associated with acute stress disorder
associated with pregnancy complications; protein:increased expression:brain (rat)		 RGD PMID:23185589 PMID:17331503 PMID:19324071 PMID:30632088 PMID:31442272 More... RGD:401851068, RGD:407571675, RGD:401901600, RGD:401901284, RGD:401851072, RGD:401901281 NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Gad1 glutamate decarboxylase 1 IEP mRNA:increased expression:dentate gyrus granule cell layer RGD PMID:15673448 RGD:401900167 NCBI chr 3:75,777,260...75,818,099
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 treatment
exacerbates		 ISO
IEP
IMP		 CTD Direct Evidence: marker/mechanism
protein:increased expression:shell of nucleus accumbens, cell surface (rat)
protein:decreased phosphorylation:caudate-putamen, nucleus accumbens (rat)
protein:altered expression:prefrontal cortex, membrane (rat)
rat gene in a mouse model
protein:increased phosphorylation:nucleus accumbens (rat)		 CTD
RGD		 PMID:11404432 PMID:25746394 PMID:34390773 PMID:15287884 PMID:31209728 More... RGD:11087075, RGD:405818276, RGD:405650198, RGD:405649863, RGD:405649739, RGD:405101690, RGD:405100728, RGD:405100238, RGD:405096668, RGD:401976466 NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 IMP RGD PMID:37190555 RGD:596933068 NCBI chr 2:168,247,490...168,367,616
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 treatment ISO RGD PMID:30632088 RGD:401901284 NCBI chr 3:28,501,836...28,528,754
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:12878694 NCBI chr10:6,136,458...6,560,003
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B treatment ISO RGD PMID:35447543 RGD:405650692 NCBI chr 8:91,395,405...91,414,815
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A ISO protein:increased expression:prefrontal cortex RGD PMID:28082900 RGD:401900741 NCBI chr15:56,360,647...56,428,703
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 treatment ISO
IDA		 protein:increased phosphorylation:central amygdaloid nucleus RGD PMID:33609567 PMID:29024786 PMID:19052216 PMID:18772347 PMID:27461790 RGD:401940121, RGD:401959607, RGD:401959374, RGD:401950487, RGD:401940145 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 treatment ISO
IDA		 protein:increased phosphorylation:central amygdaloid nucleus RGD PMID:33609567 PMID:29024786 PMID:19052216 PMID:18772347 PMID:27461790 RGD:401940121, RGD:401959607, RGD:401959374, RGD:401950487, RGD:401940145 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mc4r melanocortin 4 receptor IEP mRNA:altered expression:brain RGD PMID:8794897 RGD:1566548 NCBI chr18:62,689,798...62,691,685
Ensembl chr18:60,419,832...60,421,719 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20519536 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Ncam1 neural cell adhesion molecule 1 IEP protein:decreased expression, altered form:hippocampus (rat) RGD PMID:15673448 RGD:401900167 NCBI chr 8:58,762,088...59,062,131
Ensembl chr 8:49,865,633...50,166,014 		JBrowse link
G Ngf nerve growth factor IEP mRNA,protein:increased expression:central amygdaloid nucleus RGD PMID:22871918 RGD:401965392 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Nos1 nitric oxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17989510 NCBI chr12:44,276,011...44,456,371
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Nps neuropeptide S IDA RGD PMID:23684726 RGD:9831198 NCBI chr 1:199,505,772...199,510,915
Ensembl chr 1:190,077,040...190,080,821 		JBrowse link
G Npsr1 neuropeptide S receptor 1 IEP RGD PMID:23684726 RGD:9831198 NCBI chr 8:30,882,830...31,107,425
Ensembl chr 8:22,606,946...22,831,558 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 treatment IDA RGD PMID:27618384 RGD:408345246 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 treatment IMP RGD PMID:22304485 RGD:401965468 NCBI chr19:47,619,853...47,964,089
Ensembl chr19:30,715,648...31,059,885 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 treatment IEP
ISO
IMP		 mRNA:increased expression:hippocampus RGD PMID:28940732 PMID:32323150 PMID:32860885 RGD:596936232, RGD:596936415, RGD:596936242 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Oprl1 opioid related nociceptin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11027224 NCBI chr 3:189,209,495...189,225,406
Ensembl chr 3:168,834,003...168,839,920 		JBrowse link
G Oprm1 opioid receptor, mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:3720824 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Pdyn prodynorphin treatment IEP RGD PMID:15976090 RGD:401850590 NCBI chr 3:137,354,161...137,366,503
Ensembl chr 3:116,900,992...116,913,334 		JBrowse link
G Pomc proopiomelanocortin IEP mRNA:decreased expression:hypothalamus
protein:decreased expression:brain		 RGD PMID:8883945 PMID:6268419 RGD:405878077, RGD:408345193 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Rack1 receptor for activated C kinase 1 ISO mRNA, protein:increased expression:hippocampus, prefrontal cortex RGD PMID:19341783 RGD:401940119 NCBI chr10:33,668,560...33,676,031
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
G Rgs11 regulator of G-protein signaling 11 treatment ISO RGD PMID:15199376 RGD:597830059 NCBI chr10:15,727,279...15,735,536
Ensembl chr10:15,222,803...15,231,060 		JBrowse link
G Rgs6 regulator of G-protein signaling 6 treatment ISO RGD PMID:15199376 RGD:597830059 NCBI chr 6:107,875,883...108,527,472
Ensembl chr 6:102,264,447...102,824,753 		JBrowse link
G Rgs7 regulator of G-protein signaling 7 treatment ISO RGD PMID:15199376 RGD:597830059 NCBI chr13:89,511,492...89,941,082
Ensembl chr13:86,979,279...87,408,888 		JBrowse link
morphine withdrawal syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arc activity-regulated cytoskeleton-associated protein treatment IEP RGD PMID:30550948 RGD:401959617 NCBI chr 7:108,444,959...108,448,413
Ensembl chr 7:106,555,785...106,559,378 		JBrowse link
G Avp arginine vasopressin ISO
IEP		 protein:increased expression:hippocampal formation
mRNA:increased expression:hypothalamus		 RGD PMID:3556459 PMID:23805290 RGD:596933083, RGD:407572522 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Bad BCL2-associated agonist of cell death ISO protein:increased expression:brain cortex, hippocampus: RGD PMID:16496378 RGD:407574727 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bdnf brain-derived neurotrophic factor IEP mRNA:increased expression:ventral tegmental area (rat)
mRNA:decreased expression:dorsal raphe nucleus
mRNA, protein:increased expression:amygdala		 RGD PMID:30550948 PMID:24055683 PMID:32860885 PMID:26567727 RGD:401959617, RGD:405866344, RGD:596936242, RGD:596936230 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Cartpt CART prepropeptide IEP mRNA, protein:increased expression:nucleus accumbens RGD PMID:26955782 RGD:597805883 NCBI chr 2:32,989,215...32,991,794
Ensembl chr 2:31,255,098...31,290,713 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 treatment IDA RGD PMID:21171355 RGD:401959750 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Dbi diazepam binding inhibitor disease_progression IEP mRNA:increased expression:brain (rat) RGD PMID:15950760 RGD:408361840 NCBI chr13:33,794,231...33,802,632
Ensembl chr13:31,206,988...31,268,693 		JBrowse link
G Egr1 early growth response 1 treatment IEP RGD PMID:30550948 RGD:401959617 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit IEP mRNA:increased expression:caudate putamen,nucleus accumbens
protein:increased expression:central nervous system
protein:increased expression:periaqueductal gray,neuron		 RGD PMID:11122358 PMID:12814374 PMID:9460759 RGD:405100959, RGD:405101374, RGD:405100960 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase ameliorates ISO RGD PMID:28818835 RGD:597538594 NCBI chr20:44,322,635...44,514,498
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Galr1 galanin receptor 1 ISO mRNA:increased expression:brain,locus ceruleus (mouse) RGD PMID:10882839 RGD:407984714 NCBI chr18:78,046,803...78,062,359
Ensembl chr18:75,772,023...75,787,577 		JBrowse link
G Gdnf glial cell derived neurotrophic factor IEP mRNA:increased expression:frontal cortex RGD PMID:11798749 RGD:728679 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Gfra1 GDNF family receptor alpha 1 IEP mRNA:increased expression:frontal cortex RGD PMID:11798749 RGD:728679 NCBI chr 1:267,325,297...267,557,037
Ensembl chr 1:257,321,742...257,551,473 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 IEP
IMP		 associated with Pain;protein:increased expression:central amygdaloid nucleus (rat)
protein:increased phosphorylation:hippocampal formation, postsynaptic density (rat)
mRNA:altered expression:cerebral cortex, hippocampus (rat)		 RGD PMID:25716866 PMID:19077125 PMID:10822164 PMID:25716866 RGD:401976466, RGD:405101691, RGD:405100240, RGD:401976466 NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 treatment IMP RGD PMID:25308750 RGD:401965469 NCBI chr19:47,619,853...47,964,089
Ensembl chr19:30,715,648...31,059,885 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 treatment IMP
IEP		 mRNA:decreased expression:dorsal raphe nucleus RGD PMID:26567727 PMID:24055683 PMID:32860885 RGD:596936230, RGD:405866344, RGD:596936242 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Oprd1 opioid receptor, delta 1 IMP RGD PMID:12814374 RGD:405101374 NCBI chr 5:149,590,244...149,624,999
Ensembl chr 5:144,306,188...144,340,960 		JBrowse link
G Oprk1 opioid receptor, kappa 1 IMP RGD PMID:12814374 RGD:405101374 NCBI chr 5:18,657,866...18,675,671
Ensembl chr 5:13,860,021...13,877,823 		JBrowse link
G Oprm1 opioid receptor, mu 1 ameliorates IMP
ISO		 RGD PMID:12814374 PMID:28818835 RGD:405101374, RGD:597538594 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Per2 period circadian regulator 2 ameliorates ISO RGD PMID:20434889 RGD:401976532 NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:92,007,296...92,049,459 		JBrowse link
G Pomc proopiomelanocortin IEP mRNA:decreased expression:hypothalamus
mRNA, protein:altered expression:hypothalamus, plasma
protein:increased expression:plasma		 RGD PMID:8883945 PMID:23805290 PMID:18180322 RGD:405878077, RGD:407572522, RGD:407572517 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ameliorates ISO RGD PMID:28818835 RGD:597538594 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
neonatal abstinence syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase treatment
ameliorates		 ISO DNA:SNPs:cds: (rs4680,rs750603) c.158A>G (human)
associated with maternal opioid abuse;DNA:SNP:intron (rs740603) (human)
DNA:SNP: 158A>G (rs4680) (human)		 RGD PMID:27983768 PMID:26233486 PMID:23632726 RGD:401950496, RGD:11079504, RGD:11097592 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 treatment ISO DNA:SNP: :CYP2B6*6 (516G>T,785A>G) ((human) RGD PMID:28320034 RGD:401901176 NCBI chr 1:90,780,468...90,859,852
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A ISO mRNA:decreased expression:placenta RGD PMID:34352367 RGD:401938659 NCBI chr10:6,136,458...6,560,003
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Oprk1 opioid receptor, kappa 1 severity ISO associated with maternal opioid abuse;DNA:SNP:intron (rs702764) (human) RGD PMID:26233486 RGD:11079504 NCBI chr 5:18,657,866...18,675,671
Ensembl chr 5:13,860,021...13,877,823 		JBrowse link
G Oprm1 opioid receptor, mu 1 treatment
ameliorates		 ISO DNA:SNP: 118A>G (rs1799971) (human)
associated with maternal opioid abuse;DNA:SNP:intron (rs1799971) (human)		 RGD PMID:23632726 PMID:26233486 RGD:11097592, RGD:11079504 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Pnoc prepronociceptin severity ISO associated with maternal opioid abuse;DNA:SNP:intron (rs732636|rs351776|rs2614095 ) (human) RGD PMID:26233486 RGD:11079504 NCBI chr15:43,800,240...43,827,841
Ensembl chr15:39,624,641...39,651,867 		JBrowse link
nicotine dependence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A susceptibility ISO DNA:SNP:promoter: C-1291G (rs1800544) (human) RGD PMID:17612790 RGD:401976458 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Ahr aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25482063 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Ankk1 ankyrin repeat and kinase domain containing 1 susceptibility
treatment
onset		 ISO DNA:polymorphism:exon:
associated with depressive disorder;DNA:SNP:exon:rs1800497(human)
DNA:SNPs,haplotype:introns,exons:multiple
DNA:SNP, haplotype:exon:rs1800497(human)
DNA:SNP,haplotype: :rs11604671, rs4938015 (human)
DNA:haplotype: :multiple
DNA:SNP:exon:rs2734849(human)		 RGD PMID:28574012 PMID:21540761 PMID:17085484 PMID:22382052 PMID:21936764 More... RGD:401959222, RGD:401959399, RGD:401959319, RGD:401959315, RGD:401959296, RGD:401959295, RGD:401959232 NCBI chr 8:58,676,327...58,685,012
Ensembl chr 8:49,779,862...49,788,024 		JBrowse link
G Apbb1 amyloid beta precursor protein binding family B member 1 susceptibility ISO DNA:SNPs,haplotype:multiple: RGD PMID:18777128 RGD:10054043 NCBI chr 1:169,308,719...169,332,372
Ensembl chr 1:159,896,880...159,920,627 		JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 ISO DNA:hypermethylation:promoter, blood RGD PMID:35170441 RGD:407987268 NCBI chr 7:10,043,010...10,065,037
Ensembl chr 7:9,392,336...9,414,310 		JBrowse link
G Arrb2 arrestin, beta 2 severity ISO DNA,SNPs,haplotype: :
DNA:polymorphisms:cds:p.T84P, p.H281Q (human)		 RGD PMID:17579607 PMID:25450229 RGD:401901594, RGD:11526246 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Arvcf ARVCF, delta catenin family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:38025780 NCBI chr11:96,092,451...96,150,144
Ensembl chr11:82,587,881...82,645,805 		JBrowse link
G Bdnf brain-derived neurotrophic factor IEP
ISO		 associated with alcohol use disorder;mRNA:increased expression:shell of nucleus accumbens
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:17186223 PMID:25155311 RGD:405850247 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Cck cholecystokinin susceptibility ISO DNA:SNP:promoter: -45C>T (human) RGD PMID:11509018 RGD:407419875 NCBI chr 8:130,031,012...130,037,702
Ensembl chr 8:121,153,500...121,160,084 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit susceptibility
severity		 ISO DNA:SNP: :rs578776(human)
CTD Direct Evidence: marker/mechanism
DNA:missense:cds:p.R37H (human)
DNA:SNPs:intron 1,3'UTR: (rs637137,rs578776) (human)
DNA:SNPs:intron,CDS:rs938682,rs1051730 (human)
DNA:SNP:exon: (rs1051730) (human)
associated with smoking; DNA:SNP::rs1051730(human)		 CTD
RGD		 PMID:18414406 PMID:29666375 PMID:19706762 PMID:22042774 PMID:21312287 More... RGD:150524362, RGD:405849405, RGD:401959233, RGD:401901143, RGD:151660346, RGD:150526806 NCBI chr 8:64,297,755...64,311,251
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit ISO ClinVar Annotator: match by term: CHRNA4-related condition | ClinVar Annotator: match by term: Nicotine addiction, protection against | ClinVar Annotator: match by term: Tobacco use disorder ClinVar
OMIM		 PMID:15154117 PMID:19058950 PMID:19628475 PMID:21107856 PMID:21683344 More... NCBI chr 3:188,506,802...188,535,558
Ensembl chr 3:168,136,266...168,156,957 		JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit susceptibility
severity		 ISO DNA:SNP: :rs16969968(human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :rs16969968, rs2036527(human)
DNA:SNP, missense:CDS:rs16969968 (human)
DNA:SNP:intron:rs17486278(human)
associated with smoking; DNA:SNP::rs16969968 (human)		 CTD
RGD		 PMID:18414406 PMID:18519132 PMID:28472521 PMID:19706762 PMID:21618602 More... RGD:150524362, RGD:596933092, RGD:405849275, RGD:401901143, RGD:150527839, RGD:150526806 NCBI chr 8:64,265,879...64,294,233
Ensembl chr 8:55,369,794...55,398,146 		JBrowse link
G Chrna6 cholinergic receptor nicotinic alpha 6 subunit susceptibility ISO DNA:SNP,haplotypes: :
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs2304297(human)		 CTD
RGD		 PMID:28851948 PMID:28851948 PMID:18704094 RGD:405849281, RGD:405849394 NCBI chr16:71,400,615...71,407,315
Ensembl chr16:64,697,741...64,704,441 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:24289814 NCBI chr 1:126,123,425...126,249,181
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit susceptibility
no_association		 ISO DNA:SNP,haplotype:: rs6474413, rs13277254 (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :rs4953, rs6474413(human)
DNA:SNPs: :rs7004381, rs4950,rs13280604(human)
DNA:SNPs,haplotype: :
associated with Parkinson's disease;DNA:polymorphism:promoter:c.-57A>G(human)		 CTD
RGD		 PMID:28851948 PMID:34368810 PMID:19482438 PMID:18704094 PMID:28851948 More... RGD:405849274, RGD:405849404, RGD:405849394, RGD:405849281, RGD:405849280 NCBI chr16:71,411,847...71,454,225
Ensembl chr16:64,714,169...64,751,360 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit susceptibility ISO DNA:missense:cds:p.T91I, p.T375I (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:29666375 PMID:22042774 RGD:405849405 NCBI chr 8:64,312,644...64,333,319
Ensembl chr 8:55,418,313...55,437,027 		JBrowse link
G Comt catechol-O-methyltransferase susceptibility
sexual_dimorphism
onset
treatment		 ISO DNA:SNP:cd: (rs4680) (human)
DNA:SNPs,haplotypes:promoter,exons:mutliple
DNA:SNPs,haplotype:intron 1: (rs9332377) (human)
DNA:hypermethylation:promoter
DNA:promoter:methylation
DNA:SNP:exon 3: G1947A, p.V158M (rs4680) (human)
DNA:SNPs:3'utr: (rs737865, rs165599) (human)
DNA:SNPs,haplotypes:intron1,exon 4,intron 5: (rs740603,rs4680, rs174699) (human)
DNA:SNP:cd: p.V158M (human)		 RGD PMID:28472995 PMID:16499480 PMID:21312287 PMID:24902721 PMID:21423427 More... RGD:401940107, RGD:401959300, RGD:401959233, RGD:401940112, RGD:401959312, RGD:401959230, RGD:401940189, RGD:401940152, RGD:401940136 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 treatment ISO mRNA:increased expression:blood, leukocytes RGD PMID:19212318 PMID:20047710 RGD:401940142, RGD:401960087 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 treatment
susceptibility		 ISO DNA:polymorphisms: :1459 C/T(human)
DNA:SNP: :CYP2B6*6 (516G>T,785A>G) ((human)
DNA:SNP: :rs2279343(human)		 RGD PMID:17654295 PMID:25489907 PMID:26153084 PMID:17223085 RGD:11096878, RGD:401901146, RGD:11097624, RGD:401901145 NCBI chr 1:90,780,468...90,859,852
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Dbi diazepam binding inhibitor ISO mRNA:increased expression:cerebral cortex (mouse) RGD PMID:11750077 RGD:408356485 NCBI chr13:33,794,231...33,802,632
Ensembl chr13:31,206,988...31,268,693 		JBrowse link
G Ddc dopa decarboxylase susceptibility ISO DNA:SNPs,haplotypes::
DNA:SNPs,haplotypes:multiple
DNA:SNPs,haplotypes:introns:multiple (human)		 RGD PMID:17184203 PMID:15879433 PMID:16740595 RGD:401976473, RGD:401976477, RGD:401976474 NCBI chr14:90,592,304...90,682,830
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29216386 NCBI chr13:84,726,412...84,851,032
Ensembl chr13:82,195,463...82,317,363 		JBrowse link
G Dhrs7 dehydrogenase/reductase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29216386 NCBI chr 6:97,068,149...97,083,744
Ensembl chr 6:91,251,323...91,347,892 		JBrowse link
G Drd2 dopamine receptor D2 susceptibility
treatment		 ISO DNA:polymorphisms, haplotype:enhancer, promoter, intron:multiple
CTD Direct Evidence: marker/mechanism
DNA:SNPs, insertion/deletion:exon,introns, promoter:multiple
DNA:SNP, haplotype:exon:rs6277 (957C>T)(human)
DNA:polymorphisms: :(human)		 CTD
RGD		 PMID:18579413 PMID:17108814 PMID:17085484 PMID:22382052 PMID:17654295 RGD:1600904, RGD:401959319, RGD:401959315, RGD:11096878 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd4 dopamine receptor D4 susceptibility ISO DNA:repeats:exon: RGD PMID:31903031 RGD:401959740 NCBI chr 1:205,825,937...205,829,124
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Egfr epidermal growth factor receptor IEP mRNA, protein:increased expression:lung (rat) RGD PMID:21475988 RGD:5131452 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Fignl1 fidgetin-like 1 susceptibility ISO DNA:SNP,haplotype:: (rs10230343) (human) RGD PMID:16740595 RGD:401976474 NCBI chr14:90,573,090...90,595,342
Ensembl chr14:86,368,675...86,377,455 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit treatment IEP
ISO		 protein:increased expression:caudate-putamen
protein:increased expression:brain		 RGD PMID:15026155 PMID:22048468 PMID:9789813 PMID:26169054 RGD:405100963, RGD:405295496, RGD:405255653, RGD:405101700 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit ISO
IEP		 protein:increased expression:nucleus accumbens, dentate gyrus of hippocampal formation (rat) RGD PMID:17468183 PMID:17333132 RGD:401900124, RGD:407571683 NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 susceptibility ISO DNA:SNPs,haplotypes:intron 6,exon 16,intron 17: (rs2267635,rs29230, rs29267) RGD PMID:19763258 RGD:401940104 NCBI chr20:1,469,779...1,499,352
Ensembl chr20:1,464,534...1,493,994 		JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 susceptibility ISO
IEP		 ClinVar Annotator: match by term: Tobacco addiction, susceptibility to
mRNA, protein:altered expression:brain
DNA:SNPs,haplotypes:multiple		 ClinVar
OMIM
RGD		 PMID:25741868 PMID:28492532 PMID:16794563 PMID:19763258 RGD:408395148, RGD:401940104 NCBI chr 5:65,743,073...66,083,695
Ensembl chr 5:60,947,526...61,288,104 		JBrowse link
G Galr1 galanin receptor 1 susceptibility ISO DNA:SNP:intron: (rs2717162) (human) RGD PMID:21430647 RGD:407984717 NCBI chr18:78,046,803...78,062,359
Ensembl chr18:75,772,023...75,787,577 		JBrowse link
G Gdnf glial cell derived neurotrophic factor ISO
IEP		 protein:decreased expression:hippocampus, striatum
associated with alcohol use disorder;mRNA:decreased expression:shell of nucleus accumbens		 RGD PMID:34508846 PMID:25155311 RGD:405850211, RGD:405850247 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B severity ISO DNA:SNP: :rs2268132 RGD PMID:28900078 RGD:401900295 NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G H19 H19 imprinted maternally expressed transcript ISO CTD Direct Evidence: marker/mechanism CTD PMID:32739445 NCBI chr 1:207,160,175...207,162,851
Ensembl chr 1:197,730,698...197,733,134 		JBrowse link
G Hcrt hypocretin neuropeptide precursor ISO mRNA:increased expression:blood (human) RGD PMID:22846875 RGD:401960066 NCBI chr10:86,190,289...86,191,524
Ensembl chr10:85,689,465...85,691,210 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A treatment IEP RGD PMID:22921986 RGD:405850243 NCBI chr 2:38,427,169...38,431,733
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B sexual_dimorphism ISO associated with attention deficit hyperactivity disorder;DNA:SNPs: :rs11568817,rs130058 (human) RGD PMID:28923721 RGD:405650695 NCBI chr 8:91,395,405...91,414,815
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A severity
treatment		 ISO
IMP		 DNA:SNP: :rs6313
DNA:SNPs:promoter, CDS:-1438A>G (rs6311), 102T>C (rs6313)		 RGD PMID:28900078 PMID:22342986 PMID:25366721 RGD:401900295, RGD:401901205, RGD:401900763 NCBI chr15:56,360,647...56,428,703
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C treatment IDA RGD PMID:22342986 RGD:401901205 NCBI chr  X:115,453,190...115,682,325
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A ISO DNA:SNP, haplotype:enhancer: (rs897685) (human)
DNA:SNP, haplotype:intron: (rs10160548) (human)
DNA:SNP:intron: (rs1985242) (human)
DNA:SNPs, haplotype:multiple (human)		 RGD PMID:24590108 PMID:30405098 PMID:35457612 PMID:23290502 RGD:404976878, RGD:405096439, RGD:405096438, RGD:405096435 NCBI chr 8:58,138,514...58,150,960
Ensembl chr 8:49,242,020...49,254,389 		JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO associated with Graves Ophthalmopathy RGD PMID:10792346 RGD:8549806 NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28864214 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 susceptibility ISO DNA:SNP:: (rs1886040) (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:18438686 PMID:18438686 RGD:401851917 NCBI chr15:56,846,375...56,954,090
Ensembl chr15:50,488,149...50,544,680 		JBrowse link
G Lhb luteinizing hormone subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:12893845 NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972 		JBrowse link
G Lysmd3 LysM domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438686 NCBI chr 2:13,669,465...13,675,622
Ensembl chr 2:11,933,768...11,942,961 		JBrowse link
G Mir218-2 microRNA 218-2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28864214 NCBI chr10:20,572,523...20,572,632
Ensembl chr10:20,068,451...20,068,560 		JBrowse link
G Ncam1 neural cell adhesion molecule 1 susceptibility ISO DNA:SNPs:introns:multiple RGD PMID:17085484 RGD:401959319 NCBI chr 8:58,762,088...59,062,131
Ensembl chr 8:49,865,633...50,166,014 		JBrowse link
G Ngf nerve growth factor ISO protein:increased expression:hippocampus RGD PMID:34508846 RGD:405850211 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 ISO DNA:SNP, haplotype:exon: (rs10033119) (human) RGD PMID:22309839 RGD:402463945 NCBI chr16:27,804,416...27,814,070
Ensembl chr16:23,037,789...23,046,759 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 ISO DNA:SNP : rs6198 RGD PMID:23543128 RGD:408345225 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nrg1 neuregulin 1 sexual_dimorphism ISO in female;DNA:SNP: :rs6994992(human) RGD PMID:27353026 RGD:405100235 NCBI chr16:65,954,084...67,007,484
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Nrxn3 neurexin 3 ameliorates
severity		 ISO DNA:SNP, haplotype: :rs1424850|rs221497|rs221473 (human)
DNA:polymorphisms:cds:(rs199840331, p.Y234), p.G696, p.T99P (human)
associated with schizophrenia;DNA:SNP:exon 5 (rs1004212) (human)		 RGD PMID:22716474 PMID:25450229 PMID:19658047 RGD:402528880, RGD:11526246, RGD:405096432 NCBI chr 6:113,372,667...115,004,073
Ensembl chr 6:107,641,780...109,272,044 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 IEP
ISO		 mRNA, protein:altered expression:brain
DNA:SNP: :rs150692457 (p.L140F)
DNA:SNPs: :multiple
DNA:SNPs, haplotypes		 RGD PMID:16794563 PMID:25450229 PMID:21618602 PMID:18534558 PMID:16713586 RGD:408395148, RGD:11526246, RGD:596933092, RGD:408418728, RGD:408395150 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Nts neurotensin ameliorates IDA RGD PMID:18687313 RGD:597000688 NCBI chr 7:39,451,484...39,460,888
Ensembl chr 7:37,564,533...37,574,423 		JBrowse link
G Oprm1 opioid receptor, mu 1 no_association
disease_progression		 ISO DNA:SNP: :rs510769
DNA:SNPs: :multiple		 RGD PMID:26042510 PMID:19959688 RGD:401827930, RGD:401827943 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Pitrm1 pitrilysin metallopeptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29216386 NCBI chr17:68,705,699...68,737,350
Ensembl chr17:63,795,671...63,839,907 		JBrowse link
G Plekhg1 pleckstrin homology and RhoGEF domain containing G1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438686 NCBI chr 1:42,612,023...42,841,727
Ensembl chr 1:40,311,221...40,434,063 		JBrowse link
G Pomc proopiomelanocortin ISO DNA:hypermethylation:promoter RGD PMID:29871818 RGD:405878073 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Rabep2 rabaptin, RAB GTPase binding effector protein 2 IEP protein:increased expression:brain RGD PMID:9789813 RGD:405255653 NCBI chr 1:190,433,501...190,457,241
Ensembl chr 1:181,010,305...181,026,648 		JBrowse link
G Rad52 RAD52 homolog, DNA repair protein susceptibility ISO DNA:SNP:3'utr: (rs7963551) (human) RGD PMID:26629180 RGD:151660337 NCBI chr 4:154,778,320...154,802,002
Ensembl chr 4:153,106,062...153,128,207 		JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 ISO DNA:snps:introns: (rs2072115), (rs2074533) (human) RGD PMID:15274052 RGD:9835361 NCBI chr 7:130,754,883...130,777,303
Ensembl chr 7:128,875,773...128,898,521 		JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 susceptibility ISO DNA:SNP:: (rs1062935) (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:18438686 RGD:401851917 NCBI chr10:105,376,943...105,675,416
Ensembl chr10:104,878,487...105,176,983 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 severity ISO ClinVar Annotator: match by term: SLC6A3-related condition | ClinVar Annotator: match by term: Tobacco addiction, susceptibility to
DNA:repeats: :		 ClinVar
OMIM
RGD		 PMID:25741868 PMID:28263315 PMID:28492532 PMID:27490263 PMID:25526961 RGD:401959207, RGD:401959206 NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Tlr3 toll-like receptor 3 ISO mRNA:decreased expression:olfactory epithelial cell (human) RGD PMID:20935192 RGD:5129228 NCBI chr16:53,554,916...53,572,321
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tph1 tryptophan hydroxylase 1 ISO RGD PMID:15635702 RGD:1580461 NCBI chr 1:106,293,695...106,314,628
Ensembl chr 1:97,157,409...97,178,344 		JBrowse link
G Ttc12 tetratricopeptide repeat domain 12 susceptibility ISO DNA:haplotype: :rs2282511(human)
DNA:SNP: :rs2236709(human)
DNA:SNPs::
DNA:SNPs,haplotype:introns,intergenics:multiple		 RGD PMID:25273375 PMID:30104163 PMID:21168125 PMID:17085484 RGD:401959295, RGD:405866371, RGD:405866370, RGD:401959319 NCBI chr 8:58,696,381...58,743,857
Ensembl chr 8:49,799,920...49,847,087 		JBrowse link
opiate dependence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A severity
susceptibility
treatment		 ISO DNA:SNP: :3435C>T (rs1045642) (human)
DNA:SNP:: (rs9282564)
DNA:SNPs::rs1045642, rs2032582(human)
DNA:haplotype::		 RGD PMID:27061230 PMID:24950410 PMID:24086514 PMID:17178268 RGD:401959589, RGD:401827941, RGD:401901242, RGD:401901190 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 sexual_dimorphism IEP mRNA:increased expression:hippocampal formation RGD PMID:31071414 RGD:405866388 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Ankk1 ankyrin repeat and kinase domain containing 1 susceptibility ISO DNA:SNP,haplotype:exon:rs1800497(human) RGD PMID:19373123 RGD:401959309 NCBI chr 8:58,676,327...58,685,012
Ensembl chr 8:49,779,862...49,788,024 		JBrowse link
G Arrb2 arrestin, beta 2 treatment ISO DNA:SNPs: :rs3786047, rs1045280, rs2036657(human)
protein:decreased expression:pre-frontal cortex		 RGD PMID:20514076 PMID:14969742 RGD:401901595, RGD:401901596 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Avp arginine vasopressin ISO protein:decreased expression:serum RGD PMID:23406607 RGD:596933090 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Bdnf brain-derived neurotrophic factor ISO protein:increased expression:serum RGD PMID:21890593 RGD:405850248 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bmper BMP-binding endothelial regulator susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:SNP:: (rs731844) (human)		 CTD
RGD		 PMID:18438686 PMID:18438686 RGD:401851917 NCBI chr 8:30,008,049...30,253,201
Ensembl chr 8:21,732,225...21,977,256 		JBrowse link
G C3 complement C3 ISO protein:increased expression:serum RGD PMID:23850638 RGD:408395144 NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G C9 complement C9 susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:SNP:: (rs476569) (human)		 CTD
RGD		 PMID:18438686 PMID:18438686 RGD:401851917 NCBI chr 2:57,300,510...57,348,759
Ensembl chr 2:55,572,992...55,621,338 		JBrowse link
G Ces1d carboxylesterase 1D ISO CTD Direct Evidence: therapeutic CTD PMID:12679808 NCBI chr19:30,046,494...30,085,039
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Comt catechol-O-methyltransferase severity
treatment		 ISO DNA:SNP:cd: p.V158M (rs4680) (human) RGD PMID:27061230 PMID:32407152 RGD:401959589, RGD:401959744 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Crp C-reactive protein ISO protein:increased expression:serum RGD PMID:23850638 RGD:408395144 NCBI chr13:87,694,062...87,695,978
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 treatment ISO RGD PMID:10653207 RGD:401901270 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Drd2 dopamine receptor D2 treatment
susceptibility		 ISO DNA:SNP: :rs6275(human)
DNA:SNP,haplotype: :rs1076560,rs6275(human)		 RGD PMID:19373123 PMID:19373123 RGD:401959309, RGD:401959309 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Gal galanin and GMAP prepropeptide susceptibility ISO DNA:SNP: :rs948854(human) RGD PMID:24086514 RGD:401901242 NCBI chr 1:210,079,709...210,084,572
Ensembl chr 1:200,650,439...200,654,959 		JBrowse link
G Galr1 galanin receptor 1 susceptibility ISO DNA:SNP, haplotype:: (rs9807208) (human) RGD PMID:32757697 RGD:402463942 NCBI chr18:78,046,803...78,062,359
Ensembl chr18:75,772,023...75,787,577 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO protein:decreased expression:pre-frontal cortex RGD PMID:14969742 RGD:401901596 NCBI chr 1:211,010,259...211,031,013
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Grk6 G protein-coupled receptor kinase 6 ISO protein:decreased expression:pre-frontal cortex RGD PMID:14969742 RGD:401901596 NCBI chr17:9,182,160...9,198,380
Ensembl chr17:9,177,019...9,192,644 		JBrowse link
G Nav3 neuron navigator 3 susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:SNP:: (rs770124) (human)		 CTD
RGD		 PMID:18438686 PMID:18438686 RGD:401851917 NCBI chr 7:46,938,577...47,726,839
Ensembl chr 7:45,054,296...45,840,698 		JBrowse link
G Ngf nerve growth factor ISO DNA:hypermethylation:promoter,exon:blood
protein:decreased expression:brain		 RGD PMID:29224006 PMID:26440527 RGD:401976280, RGD:401976545 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 susceptibility ISO DNA:SNP, haplotype:enhancer: (rs4128839) (human)
DNA:SNP, haplotype:intron: (rs4691910) (human)		 RGD PMID:31689297 PMID:32757697 RGD:402463939, RGD:402463942 NCBI chr16:27,804,416...27,814,070
Ensembl chr16:23,037,789...23,046,759 		JBrowse link
G Ntsr1 neurotensin receptor 1 susceptibility ISO DNA:SNP:intron:rs3915568(human) RGD PMID:26384852 RGD:11522680 NCBI chr 3:187,983,778...188,033,934
Ensembl chr 3:167,606,215...167,656,377 		JBrowse link
G Oprd1 opioid receptor, delta 1 susceptibility
treatment		 ISO DNA:SNP: :rs1042114 (human)
DNA:SNPs, haplotype:intron 1:multiple (human)
associated with neonatal abstinence syndrome in offspring;DNA:SNP:intron (rs204076) (human)
associated with African American;DNA:SNP:intron (rs678849) (human)
associated with methadone treatment;DNA:SNP:intron (rs204076) (human)
DNA:SNP:intron (rs10753331, rs581111) (human)
DNA:SNP,haplotype:multiple (multiple)(human)
DNA:SNP, haplotype: (rs678849|rs2236857|rs2236855|rs760589) (human)
DNA:SNP: :rs2236861(human)		 RGD PMID:28656735 PMID:24533225 PMID:26233486 PMID:23612435 PMID:37531661 More... RGD:401850580, RGD:402525443, RGD:11079504, RGD:402463973, RGD:401977581, RGD:401976559, RGD:401976552, RGD:401976541, RGD:401901242 NCBI chr 5:149,590,244...149,624,999
Ensembl chr 5:144,306,188...144,340,960 		JBrowse link
G Oprk1 opioid receptor, kappa 1 no_association ISO DNA:SNP: :rs702764 (human)
DNA:SNP,haplotype:multiple (multiple GGCTTCT) (human)		 RGD PMID:28656735 PMID:17622222 RGD:401850580, RGD:401976552 NCBI chr 5:18,657,866...18,675,671
Ensembl chr 5:13,860,021...13,877,823 		JBrowse link
G Oprm1 opioid receptor, mu 1 susceptibility
treatment
no_association		 ISO ClinVar Annotator: match by term: Opioid dependence, susceptibility to, 1
protein:decreased expression:pre-frontal cortex
DNA:SNP: :rs9479757(human)
DNA:SNP, haplotype:3' utr:rs10485058 (human)
associated with Chronic Pain;DNA:missense mutation:exon:p.N40D (118A>G) (rs 1799971) (human)
DNA:altered methylation:promoter
DNA:SNPs: :multiple
associated with alcohol dependence:DNA:SNP, haplotypes: :-2044C>A (human)
DNA:SNPs: :172G>T (rs6912029), 1510G>A (rs12205732) (human)
DNA:hypermethylation:promoter
DNA:SNP:exon:17C>T (rs 1799972) (human)
DNA:SNP:exon:118A>G (rs 1799971) (human)		 ClinVar
RGD		 PMID:9193881 PMID:9689128 PMID:11134674 PMID:11773858 PMID:11773859 More... RGD:401901596, RGD:401901242, RGD:401831043, RGD:401831042, RGD:401831040, RGD:401827954, RGD:401827948, RGD:401827945, RGD:401827942, RGD:401827937, RGD:401827935, RGD:401827933, RGD:401827929, RGD:401827929 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Pdyn prodynorphin sexual_dimorphism
no_association
susceptibility		 ISO DNA:SNP: :rs1022563 (human)
DNA:SNPs:promoter, 3' utr:rs1997794, rs102256
DNA:SNP: :rs199774, rs1022563 (human)
DNA:SNP: :rs910080 (human)
DNA:SNP: :rs910080, rs199774 (human)		 RGD PMID:22443215 PMID:19298317 PMID:28656735 PMID:28656735 PMID:22443215 RGD:401850569, RGD:401850586, RGD:401850580, RGD:401850580, RGD:401850569 NCBI chr 3:137,354,161...137,366,503
Ensembl chr 3:116,900,992...116,913,334 		JBrowse link
G Penk proenkephalin ISO CTD Direct Evidence: marker/mechanism CTD PMID:10321497 NCBI chr 5:21,981,381...21,987,074
Ensembl chr 5:17,183,806...17,189,129 		JBrowse link
G Pomc proopiomelanocortin ISO associated with Psychological Trauma;protein:decreased expression:serum RGD PMID:31940647 RGD:407571691 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Ttc9 tetratricopeptide repeat domain 9 susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:SNP:: (rs8688) (human)		 CTD
RGD		 PMID:18438686 PMID:18438686 RGD:401851917 NCBI chr 6:107,064,527...107,099,361
Ensembl chr 6:101,333,141...101,368,110 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO DNA:hypermethylation:exon:blood RGD PMID:29224006 RGD:401976280 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
opiate withdrawal syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avp arginine vasopressin IEP mRNA:increased expression:amygdala RGD PMID:17443128 RGD:408364980 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Ngf nerve growth factor ISO protein:increased expression:plasma RGD PMID:8727238 RGD:401976550 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 treatment IMP associated with heroin dependence RGD PMID:24899712 RGD:596933358 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Tph2 tryptophan hydroxylase 2 treatment ISO associated with heroin dependence RGD PMID:30059533 RGD:597805899 NCBI chr 7:52,571,909...52,676,305
Ensembl chr 7:50,685,694...50,789,424 		JBrowse link
opioid abuse term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankk1 ankyrin repeat and kinase domain containing 1 susceptibility ISO associated with phlegm syndrome;DNA:polymorphism:exon: RGD PMID:26138154 RGD:11065747 NCBI chr 8:58,676,327...58,685,012
Ensembl chr 8:49,779,862...49,788,024 		JBrowse link
G Avp arginine vasopressin susceptibility ISO DNA:SNP:intron: (rs2282018) (human) RGD PMID:24766650 RGD:401976505 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 treatment IEP
ISO		 protein:increased phosphorylation:Prefrontal Cortex, nucleus accumbens (rat) RGD PMID:30632799 PMID:31081159 RGD:401901180, RGD:401940188 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crhbp corticotropin releasing hormone binding protein susceptibility ISO DNA:SNP:3'UTR: (rs1875999) (HUMAN) RGD PMID:24766650 RGD:401976505 NCBI chr 2:28,427,139...28,439,446
Ensembl chr 2:26,692,403...26,704,710 		JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 treatment ISO RGD PMID:31081159 RGD:401940188 NCBI chr10:55,239,397...55,267,780
Ensembl chr10:54,739,470...54,767,153 		JBrowse link
G Drd4 dopamine receptor D4 ISO association with inhaler;DNA:repeats:exon: RGD PMID:11054768 RGD:401960062 NCBI chr 1:205,825,937...205,829,124
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit IEP protein:increased expression:Prefrontal Cortex, nucleus accumbens (rat) RGD PMID:30632799 RGD:401901180 NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Galr1 galanin receptor 1 susceptibility ISO DNA:SNP:intron: (rs2717162) (human) RGD PMID:24766650 RGD:401976505 NCBI chr18:78,046,803...78,062,359
Ensembl chr18:75,772,023...75,787,577 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 ISO protein:increased expression:medial prefrontal cortex,lateral prefrontal cortex,orbitofrontal cortex RGD PMID:29766293 RGD:401938658 NCBI chr 3:28,501,836...28,528,754
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A ISO protein:increased expression:orbitofrontal cortex: RGD PMID:29766293 RGD:401938658 NCBI chr10:6,136,458...6,560,003
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B ISO protein:increased expression:medial prefrontal cortex,lateral prefrontal cortex,orbitofrontal cortex RGD PMID:29766293 RGD:401938658 NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A ISO mRNA:altered expression:striatum RGD PMID:30059705 RGD:401900306 NCBI chr15:56,360,647...56,428,703
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Ncam1 neural cell adhesion molecule 1 IMP RGD PMID:24399412 RGD:401959321 NCBI chr 8:58,762,088...59,062,131
Ensembl chr 8:49,865,633...50,166,014 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 treatment IMP RGD PMID:9636221 RGD:401965473 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 susceptibility ISO DNA:SNP:intron: (rs1040288) (human) RGD PMID:24766650 RGD:401976505 NCBI chr19:47,619,853...47,964,089
Ensembl chr19:30,715,648...31,059,885 		JBrowse link
G Oprd1 opioid receptor, delta 1 treatment
susceptibility		 ISO mRNA:increased expression:ventral striatum
associated with females, buprenorphine;DNA:SNP:intron (rs581111|rs529520) (human)
mRNA:altered expression:testis, omentum (human)
DNA:SNP:CDS: rs569356|rs678849 (human)		 RGD PMID:30059705 PMID:24126707 PMID:37660978 PMID:37146669 RGD:401900306, RGD:402463962, RGD:402463943, RGD:401976452 NCBI chr 5:149,590,244...149,624,999
Ensembl chr 5:144,306,188...144,340,960 		JBrowse link
G Oprk1 opioid receptor, kappa 1 severity ISO mRNA:decreased expression:peripheral blood lymphocyte
DNA:SNP:CDS: rs997917|rs12548098|rs6473797|rs963549 (human)		 RGD PMID:31710992 PMID:37146669 RGD:401850570, RGD:401976452 NCBI chr 5:18,657,866...18,675,671
Ensembl chr 5:13,860,021...13,877,823 		JBrowse link
G Oprl1 opioid related nociceptin receptor 1 ISO mRNA:increased expression:ventral striatum RGD PMID:30059705 RGD:401900306 NCBI chr 3:189,209,495...189,225,406
Ensembl chr 3:168,834,003...168,839,920 		JBrowse link
G Oprm1 opioid receptor, mu 1 treatment
susceptibility		 ISO DNA:SNP:CDS: rs648893 (human)
DNA:methylation:exon 1 (rs1799971) (human)		 RGD PMID:37146669 PMID:37660978 RGD:401976452, RGD:402463943 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Pdyn prodynorphin ISO
IEP		 mRNA, protein:increased expression:peripheral blood lymphocyte
protein:increased expression:nucleus accumbens		 RGD PMID:31710992 PMID:24305833 RGD:401850570, RGD:401850592 NCBI chr 3:137,354,161...137,366,503
Ensembl chr 3:116,900,992...116,913,334 		JBrowse link
G Pomc proopiomelanocortin ISO mRNA:increased expression:ventral striatum RGD PMID:30059705 RGD:401900306 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Rgs10 regulator of G-protein signaling 10 IEP RGD PMID:22056472 RGD:13524518 NCBI chr 1:192,376,772...192,422,640
Ensembl chr 1:182,946,336...182,987,697 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 IEP RGD PMID:19664213 RGD:13524573 NCBI chr13:58,350,063...58,352,666
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 IEP RGD PMID:22056472 RGD:13524518 NCBI chr13:84,469,593...84,475,884
Ensembl chr13:81,936,775...81,943,068 		JBrowse link
phencyclidine abuse term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apol2 apolipoprotein L2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr 7:111,211,944...111,219,209
Ensembl chr 7:109,331,392...109,338,558 		JBrowse link
G Calm1 calmodulin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr 6:125,217,191...125,227,855
Ensembl chr 6:119,487,621...119,498,227 		JBrowse link
G Calm2 calmodulin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr 6:12,845,170...12,857,830
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr14:85,059,166...85,148,121
Ensembl chr14:80,845,238...80,933,994 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr15:41,588,114...41,616,168
Ensembl chr15:37,412,146...37,440,287 		JBrowse link
G Gcc1 GRIP and coiled-coil domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr 4:57,996,261...58,008,126
Ensembl chr 4:57,032,314...57,042,663 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr12:36,957,302...37,023,982
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
Postoperative Cognitive Dysfunction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor IEP mRNA, protein:increased expression:hippocampus RGD PMID:23078219 RGD:597805826 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a IEP RGD PMID:24814703 RGD:10047100 NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Agtr1b angiotensin II receptor, type 1b IEP RGD PMID:24814703 RGD:10047100 NCBI chr 2:104,774,005...104,849,262
Ensembl chr 2:102,844,969...102,920,232 		JBrowse link
G App amyloid beta precursor protein IEP
ISO		 protein:increased expression:hippocampus
protein:increased expression:plasma		 RGD PMID:35317728 PMID:35317728 RGD:597830151, RGD:597830151 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Bdnf brain-derived neurotrophic factor treatment IEP
ISO		 associated with brain ischemia RGD PMID:29571823 PMID:32564283 PMID:30232930 PMID:29065194 PMID:33324197 More... RGD:401959211, RGD:596936414, RGD:596936243, RGD:596933096, RGD:405850212, RGD:401976548, RGD:401965400 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 treatment IDA
ISO		 protein:decreased phosphorylation:hippocampus RGD PMID:29571823 PMID:37736695 PMID:36688960 RGD:401959211, RGD:401960090, RGD:401959611 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Gdnf glial cell derived neurotrophic factor treatment IEP
ISO
IDA		 protein:decreased expression:hippocampus,urine
protein:altered expression:hippocampus, urine
associated with rheumatic heart disease;protein:increased expression:serum		 RGD PMID:36688960 PMID:34728231 PMID:29512789 PMID:28918204 PMID:33324197 More... RGD:401959611, RGD:405866364, RGD:405850251, RGD:405850250, RGD:405850212, RGD:405849389 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Hmgb1 high mobility group box 1 IEP mRNA, protein:increased expression:hippocampus RGD PMID:23078219 RGD:597805826 NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Igf1 insulin-like growth factor 1 IEP
ISO		 mRNA:decreased expression:hippocampus
mRNA:decreased expression:plasma		 RGD PMID:35317728 PMID:35317728 RGD:597830151, RGD:597830151 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 ISO protein:increased expression:plasma (human) RGD PMID:25543030 RGD:401960875 NCBI chr14:31,091,681...31,151,623
Ensembl chr14:30,737,164...30,797,314 		JBrowse link
G Il1b interleukin 1 beta treatment IDA
IEP		 mRNA, protein:increased expression:hippocampus
protein:increased expression:hippocampus (rat)		 RGD PMID:22959208 PMID:23078219 PMID:33390808 PMID:29571823 RGD:7204702, RGD:597805826, RGD:401965467, RGD:401959211 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO human protein in a rat model RGD PMID:23077050 RGD:8551854 NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il6 interleukin 6 treatment IEP protein:increased expression:hippocampus (rat) RGD PMID:33390808 PMID:28684969 RGD:401965467, RGD:597538492 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ireb2 iron responsive element binding protein 2 IEP protein:increased expression:hippocampus (rat) RGD PMID:23229539 RGD:12904023 NCBI chr 8:64,124,152...64,207,702
Ensembl chr 8:55,228,085...55,311,611 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 treatment IDA
ISO		 protein:decreased phosphorylation:hippocampus RGD PMID:36688960 PMID:37736695 RGD:401959611, RGD:401960090 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 treatment IDA
ISO		 protein:decreased phosphorylation:hippocampus RGD PMID:36688960 PMID:37736695 RGD:401959611, RGD:401960090 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mir320a microRNA 320a treatment IMP
ISO		 protein:increased expression:plasma RGD PMID:35317728 PMID:35317728 RGD:597830151, RGD:597830151 NCBI chr15:51,926,088...51,926,169
Ensembl chr15:45,516,392...45,516,473 		JBrowse link
G Ngf nerve growth factor treatment ISO
IEP		 associated with brain ischemia RGD PMID:30481505 PMID:29599834 PMID:34964700 PMID:30481505 RGD:401965395, RGD:401976548, RGD:401965400, RGD:401965395 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 treatment IDA
IEP		 associated with Traumatic Brain Injuries;mRNA:decreased expression:hippocampus, hypothalamus RGD PMID:28086911 PMID:36637480 RGD:408345237, RGD:408364984 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 IEP
IMP		 protein:increased expression:hippocampus (rat) RGD PMID:33390808 PMID:33390808 RGD:401965467, RGD:401965467 NCBI chr19:47,619,853...47,964,089
Ensembl chr19:30,715,648...31,059,885 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 treatment IEP
ISO		 RGD PMID:29065194 PMID:32564283 PMID:30232930 RGD:596933096, RGD:596936414, RGD:596936243 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Tlr2 toll-like receptor 2 treatment IEP RGD PMID:32300366 PMID:28684969 RGD:597538486, RGD:597538492 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr4 toll-like receptor 4 treatment IEP RGD PMID:32300366 PMID:28684969 RGD:597538486, RGD:597538492 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor treatment IEP mRNA, protein:increased expression:hippocampus
protein:increased expression:hippocampus (rat)		 RGD PMID:29571823 PMID:23078219 PMID:33390808 RGD:401959211, RGD:597805826, RGD:401965467 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
subacute delirium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase disease_progression ISO RGD PMID:8043620 RGD:405855847 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A IEP mRNA, protein:increased expression:hippocampal formation, amygdala RGD PMID:27760517 RGD:405850209 NCBI chr 2:38,427,169...38,431,733
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Tph2 tryptophan hydroxylase 2 IEP mRNA:increased expression:hippocampus, prefrontal cortex RGD PMID:36750928 RGD:597805905 NCBI chr 7:52,571,909...52,676,305
Ensembl chr 7:50,685,694...50,789,424 		JBrowse link
substance abuse term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A sexual_dimorphism ISO DNA:SNP:promoter: C-1291G (rs1800544) (human) RGD PMID:21140256 RGD:401976460 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Drd4 dopamine receptor D4 onset ISO associated with depressive disorder;DNA:repeats:exon:
DNA:duplication:promoter: 120bp repeat		 RGD PMID:34828440 PMID:33544778 RGD:401959596, RGD:401959602 NCBI chr 1:205,825,937...205,829,124
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISO DNA:SNP:promoter:-1019G>C (rs6295) RGD PMID:26926882 RGD:11555812 NCBI chr 2:38,427,169...38,431,733
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B sexual_dimorphism
susceptibility		 ISO associated with attention deficit hyperactivity disorder;DNA:SNP: :rs130058(human)
associated with disease of mental health; DNA:SNP: :861G>C(human)		 RGD PMID:28923721 PMID:12496953 RGD:405650695, RGD:405818271 NCBI chr 8:91,395,405...91,414,815
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Nrg1 neuregulin 1 susceptibility ISO associated with stressful life event;DNA:SNP: :rs6994992(human) RGD PMID:27353026 RGD:405100235 NCBI chr16:65,954,084...67,007,484
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Oxtr oxytocin receptor ISO DNA:promoter:methylation RGD PMID:30308385 RGD:597538590 NCBI chr 4:147,154,374...147,171,723
Ensembl chr 4:145,599,561...145,614,674 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 sexual_dimorphism ISO DNA:SNP:promoter:: RGD PMID:21140256 RGD:401976460 NCBI chr10:62,322,688...62,357,060
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
substance dependence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Creb1 cAMP responsive element binding protein 1 treatment IDA ketamine RGD PMID:27713001 RGD:401960089 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit ISO protein:decreased expression: hippocampus (human) RGD PMID:27494187 RGD:401851061 NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
substance-induced psychosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO CTD Direct Evidence: marker/mechanism CTD PMID:17196621 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Adora2a adenosine A2a receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20799992 NCBI chr20:13,315,270...13,332,802
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21041608 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:17603807 NCBI chr14:85,059,166...85,148,121
Ensembl chr14:80,845,238...80,933,994 		JBrowse link
G Esr1 estrogen receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19386276 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Grm2 glutamate metabotropic receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20211215 NCBI chr 8:116,158,810...116,171,857
Ensembl chr 8:107,280,099...107,293,146 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15729709 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19747927 NCBI chr 2:38,427,169...38,431,733
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20705401 NCBI chr 5:156,579,901...156,595,147
Ensembl chr 5:151,296,662...151,311,912 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19566775 NCBI chr16:27,804,416...27,814,070
Ensembl chr16:23,037,789...23,046,759 		JBrowse link
G Oprm1 opioid receptor, mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16402083 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Phb1 prohibitin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18504422 NCBI chr10:81,102,043...81,114,815
Ensembl chr10:80,605,251...80,618,042 		JBrowse link
G Pick1 protein interacting with PRKCA 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17606663 NCBI chr 7:112,676,890...112,697,275
Ensembl chr 7:110,797,117...110,816,848 		JBrowse link
G Rgs9 regulator of G-protein signaling 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17318883 NCBI chr10:94,696,556...94,770,387
Ensembl chr10:94,197,054...94,270,892 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12931138 NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Snca synuclein alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:15542733 NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16807759 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
Wernicke encephalopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fos Fos proto-oncogene, AP-1 transcription factor subunit treatment IEP RGD PMID:8229066 RGD:405100718 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP mRNA, protein:increased expression:medial thalamic group, inferior colliculus, neuron RGD PMID:18481165 RGD:2300278 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Tkt transketolase ISO CTD Direct Evidence: marker/mechanism CTD PMID:3762968 NCBI chr16:5,729,381...5,755,170
Ensembl chr16:5,723,762...5,748,698 		JBrowse link
Wernicke-Korsakoff syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avp arginine vasopressin ISO associated with alcohol dependence;protein:increased expression:plasma
protein:decreased expression:cerebrospinal fluid		 RGD PMID:7662042 PMID:2425205 RGD:596933082, RGD:596933106 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Pomc proopiomelanocortin ISO protein:increased expression:mammillary body RGD PMID:1650797 RGD:407572523 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
withdrawal disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy1 adenylate cyclase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16914643 NCBI chr14:86,125,119...86,234,459
Ensembl chr14:81,911,099...82,028,969 		JBrowse link
G Adcy8 adenylate cyclase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16914643 NCBI chr 7:98,306,434...98,555,687
Ensembl chr 7:96,417,324...96,665,911 		JBrowse link
G Adora1 adenosine A1 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16226742 NCBI chr13:48,210,922...48,247,826
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Adora2a adenosine A2a receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:14756803 PMID:16226742 PMID:16470403 NCBI chr20:13,315,270...13,332,802
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Ago2 argonaute RISC catalytic component 2 IEP protein:increased expression:ventral tegmental area RGD PMID:23927484 RGD:401900655 NCBI chr 7:106,907,209...106,994,124
Ensembl chr 7:105,029,120...105,104,974 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein IEP
ISO		 associated with morphine dependence;protein:increased expression:brain (rat)
associated with morphine dependence; mRNA,protein:increased expression:brain (mouse)		 RGD PMID:19262551 PMID:27730515 RGD:401938601, RGD:401959609 NCBI chr 7:108,444,959...108,448,413
Ensembl chr 7:106,555,785...106,559,378 		JBrowse link
G Arl6ip5 ARF like GTPase 6 interacting protein 5 ISO CTD Direct Evidence: therapeutic CTD PMID:21600884 NCBI chr 4:131,365,320...131,395,311
Ensembl chr 4:129,810,645...129,838,608 		JBrowse link
G Avp arginine vasopressin ISO
IEP		 CTD Direct Evidence: marker/mechanism
associated with cocaine abuse;mRNA:increased expression:paraventricular nucleus of hypothalamus		 CTD
RGD		 PMID:4040330 PMID:21677651 RGD:408418732 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Bdnf brain-derived neurotrophic factor treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism
associated with morphine dependence;mRNA:alternative form:frontal cortex, midbrain
associated with nicotine dependence		 CTD
RGD		 PMID:12574402 PMID:25392083 PMID:24682499 RGD:401950484, RGD:401940143 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I treatment ISO RGD PMID:25871318 RGD:14995950 NCBI chr 7:113,716,266...113,827,670
Ensembl chr 7:111,836,012...111,944,688 		JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV IEP associated with alcohol use disorder;protein:decreased expression:brain RGD PMID:11181917 RGD:401959326 NCBI chr18:24,857,152...25,076,054
Ensembl chr18:24,585,269...24,802,487 		JBrowse link
G Cckbr cholecystokinin B receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:9496717 PMID:11880531 NCBI chr 1:169,183,578...169,193,583
Ensembl chr 1:159,771,733...159,814,881 		JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12154229 NCBI chr 3:119,739,229...119,791,630
Ensembl chr 3:99,284,846...99,337,252 		JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:18184829 NCBI chr 8:64,265,879...64,294,233
Ensembl chr 8:55,369,794...55,398,146 		JBrowse link
G Chrna6 cholinergic receptor nicotinic alpha 6 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19644040 NCBI chr16:71,400,615...71,407,315
Ensembl chr16:64,697,741...64,704,441 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:18184829 NCBI chr 1:126,123,425...126,249,181
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:18184829 NCBI chr 2:177,479,091...177,487,306
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:15537871 NCBI chr 8:64,312,644...64,333,319
Ensembl chr 8:55,418,313...55,437,027 		JBrowse link
G Cnr1 cannabinoid receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18705688 NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Comt catechol-O-methyltransferase susceptibility ISO associated with alcohol dependence; DNA:SNP:cd: c.158G>A (human) RGD PMID:11900601 RGD:401940190 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 treatment
sexual_dimorphism		 ISO
IDA
IEP
IMP		 CTD Direct Evidence: marker/mechanism
associated with heroin dependence;protein:decreased phosphorylation:nucleus accumbens
associated with morphine dependence
associated with alcohol use disorder;protein:altered phosphorylation:brain, nucleus
associated with nicotine dependence;protein:decreased expression, decreased phosphorylation:brain, multiple
associated with alcohol dependence
associated with morphine dependence;protein:increased promoter binding:frontal cortex, midbrain
associated with morphine dependence;protein:altered phosphorylation:ventral tegmental area
associated with morphine dependence;protein:increased phosphorylation:prefrontal cortex
associated with alcohol use disorder;mRNA:increased expression:cerebellum		 CTD
RGD		 PMID:18596687 PMID:25711798 PMID:19108758 PMID:11181917 PMID:16641242 More... RGD:401959753, RGD:401959375, RGD:401959326, RGD:401959318, RGD:401959212, RGD:401950487, RGD:401950486, RGD:401950484, RGD:401940143, RGD:401938641, RGD:401938640, RGD:401938639 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crh corticotropin releasing hormone IEP
ISO		 mRNA:increased expression:amygdala (rat)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:12968131 PMID:18596687 PMID:12782395 RGD:5508177 NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Crp C-reactive protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:12858318 NCBI chr13:87,694,062...87,695,978
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Drd1 dopamine receptor D1 IEP protein:increased expression:nucleus accumbens (rat) RGD PMID:20435100 RGD:7248622 NCBI chr17:10,545,488...10,550,029
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17189962 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Faah fatty acid amide hydrolase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18705688 PMID:19002671 NCBI chr 5:134,716,545...134,735,396
Ensembl chr 5:129,479,824...129,498,677 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 IEP mRNA:decreased expression:prefrontal cortex (rat) RGD PMID:24810662 RGD:11667955 NCBI chr  X:152,284,857...152,322,686
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:15196791 PMID:15196794 PMID:18485423 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit IEP associated with morphine dependence;protein:increased expression:Brainstem (rat) RGD PMID:20438612 RGD:401900159 NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Gad1 glutamate decarboxylase 1 severity
sexual_dimorphism		 ISO
IEP		 associated with alcohol dependence;DNA:haplotype: :
in female only, associated with alcohol dependence:protein:increased expression:cerebral cortex,hippocampus		 RGD PMID:19111404 PMID:15976529 RGD:401900129, RGD:1643202 NCBI chr 3:75,777,260...75,818,099
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gad2 glutamate decarboxylase 2 IEP associated with alcohol dependence:protein:increased expression:cerebral cortex RGD PMID:15976529 RGD:1643202 NCBI chr17:89,671,718...89,734,246
Ensembl chr17:84,763,628...84,826,155 		JBrowse link
G Gnai1 G protein subunit alpha i1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12199159 NCBI chr 4:17,706,061...17,790,176
Ensembl chr 4:16,814,001...16,896,417 		JBrowse link
G Gnao1 G protein subunit alpha o1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12199159 NCBI chr19:11,040,788...11,198,437
Ensembl chr19:11,035,956...11,192,493 		JBrowse link
G Gnas GNAS complex locus ISO CTD Direct Evidence: marker/mechanism CTD PMID:12199159 NCBI chr 3:183,489,648...183,554,570
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 ameliorates ISO
IEP
IMP		 CTD Direct Evidence: marker/mechanism
benzodiazepine withdrawal;protein:increased expression:hippocampal formation, synapse (rat)
cocaine withdrawal
heroin withdrawal disorder;protein:increased phosphorylation:multiple (rat)		 CTD
RGD		 PMID:11404432 PMID:12511956 PMID:18924138 PMID:12511956 PMID:19084907 RGD:405100713, RGD:728494, RGD:401976470 NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12511956 NCBI chr 2:168,247,490...168,367,616
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A severity ISO
IEP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:12878694 PMID:23113297 RGD:401938657 NCBI chr10:6,136,458...6,560,003
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B severity IEP RGD PMID:23113297 RGD:401938657 NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 severity IEP RGD PMID:23113297 RGD:401938657 NCBI chr 2:169,716,684...169,780,360
Ensembl chr 2:167,418,640...167,481,671 		JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 severity IEP RGD PMID:23113297 RGD:401938657 NCBI chr 2:169,646,897...169,697,060
Ensembl chr 2:167,348,825...167,398,916 		JBrowse link
G Hcrt hypocretin neuropeptide precursor severity ISO CTD Direct Evidence: marker/mechanism
associated with alcohol dependence;mRNA:decreased expression:blood plasma (human)		 CTD
RGD		 PMID:20738730 PMID:21621370 RGD:401960070 NCBI chr10:86,190,289...86,191,524
Ensembl chr10:85,689,465...85,691,210 		JBrowse link
G Hcrtr1 hypocretin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20667500 NCBI chr 5:147,761,392...147,771,846
Ensembl chr 5:142,477,214...142,486,674 		JBrowse link
G Hrh1 histamine receptor H 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8870037 NCBI chr 4:149,120,511...149,204,267
Ensembl chr 4:147,645,995...147,647,455 		JBrowse link
G Hrh2 histamine receptor H 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8870037 NCBI chr17:10,371,083...10,412,979
Ensembl chr17:10,368,298...10,407,631 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 IEP associated with cocaine dependence;mRNA:increased expression:hippocampal formation (rat) RGD PMID:22860061 RGD:10445834 NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISO associated with alcohol dependence;DNA:SNP: :140G>C RGD PMID:19060480 RGD:401900293 NCBI chr 2:38,427,169...38,431,733
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A treatment ISO
IEP
IMP		 associated with alcohol dependence
mRNA:decreased expression:hippocampus, ventral tegmental area
associated with Cocaine-Related Disorders
associated with morphine dependence;mRNA:decreased expression:peripheral blood mononuclear cell		 RGD PMID:19060480 PMID:26031442 PMID:12398913 PMID:28082900 PMID:18801381 RGD:401900293, RGD:401901090, RGD:401900759, RGD:401900741, RGD:13464135 NCBI chr15:56,360,647...56,428,703
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C ISO
IEP		 CTD Direct Evidence: marker/mechanism
mRNA:decreased editing:hippocampus		 CTD
RGD		 PMID:17105947 PMID:26031442 RGD:401901090 NCBI chr  X:115,453,190...115,682,325
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Kdm4c lysine demethylase 4C susceptibility ISO DNA:snps:multiple (human) RGD PMID:22072270 RGD:9587485 NCBI chr 5:93,146,404...93,353,040
Ensembl chr 5:88,100,733...88,306,818 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 treatment ISO
IDA		 CTD Direct Evidence: marker/mechanism
associated with heroin dependence;protein:decreased phosphorylation:nucleus accumbens
associated with morphine dependence
associated with morphine dependence;protein:increased phosphorylation:prefrontal cortex		 CTD
RGD		 PMID:17549049 PMID:25711798 PMID:18772347 PMID:23035088 RGD:401959753, RGD:401950487, RGD:401938640 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 treatment ISO
IDA		 CTD Direct Evidence: marker/mechanism
associated with heroin dependence;protein:decreased phosphorylation:nucleus accumbens
associated with morphine dependence
associated with morphine dependence;protein:increased phosphorylation:prefrontal cortex		 CTD
RGD		 PMID:17549049 PMID:25711798 PMID:18772347 PMID:23035088 RGD:401959753, RGD:401950487, RGD:401938640 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20519536 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Ngf nerve growth factor ISO
IEP		 associated with alcohol dependence;DNA,protein:hypermethylation,decreased expression:promoter,serum
associated with alcohol dependence;protein:altered expression:brain
associated with alcohol dependence;protein:decreased expression:plasma		 RGD PMID:21392176 PMID:16252071 PMID:18639986 RGD:401965410, RGD:401976435, RGD:401965411 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19751225 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nptx2 neuronal pentraxin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19084905 NCBI chr12:15,151,136...15,162,045
Ensembl chr12:10,037,435...10,048,345 		JBrowse link
G Npy neuropeptide Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:16952158 NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
G Npy2r neuropeptide Y receptor Y2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18828811 NCBI chr 2:170,200,027...170,210,286
Ensembl chr 2:167,903,879...167,905,024 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 ISO associated with cocaine dependence;DNA:SNP:intron:rs41423247 RGD PMID:27397864 RGD:401976507 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 ISO associated with alcohol use disorder;protein:increased tyrosine phosphorylation:suprachiasmatic nucleus RGD PMID:29139560 RGD:408418729 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Oprd1 opioid receptor, delta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:2415332 NCBI chr 5:149,590,244...149,624,999
Ensembl chr 5:144,306,188...144,340,960 		JBrowse link
G Oprk1 opioid receptor, kappa 1 treatment IMP
IEP
ISO		 mRNA:increased expression:bed nucleus of stria terminalis
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:9463367 PMID:20232057 PMID:22515275 PMID:30075159 RGD:9834942, RGD:401850573 NCBI chr 5:18,657,866...18,675,671
Ensembl chr 5:13,860,021...13,877,823 		JBrowse link
G Oprl1 opioid related nociceptin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11027224 NCBI chr 3:189,209,495...189,225,406
Ensembl chr 3:168,834,003...168,839,920 		JBrowse link
G Oprm1 opioid receptor, mu 1 severity ISO associated with heroin dependence; DNA:SNP:CDS (rs6848893) (human) RGD PMID:26692286 RGD:11532896 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Pdyn prodynorphin IEP associated with cocaine abuse;mRNA:altered expression:hippocampal formation, nucleus accumbens
associated with opioid abuse		 RGD PMID:30818133 PMID:9045086 RGD:401851051, RGD:401851908 NCBI chr 3:137,354,161...137,366,503
Ensembl chr 3:116,900,992...116,913,334 		JBrowse link
G Per1 period circadian regulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20738730 NCBI chr10:54,299,002...54,313,804
Ensembl chr10:53,805,535...53,814,431 		JBrowse link
G Per2 period circadian regulator 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20434889 PMID:20738730 NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:92,007,296...92,049,459 		JBrowse link
G Per3 period circadian regulator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20738730 NCBI chr 5:166,740,914...166,778,243
Ensembl chr 5:161,459,533...161,495,607 		JBrowse link
G Pnoc prepronociceptin ISO CTD Direct Evidence: therapeutic CTD PMID:10680585 NCBI chr15:43,800,240...43,827,841
Ensembl chr15:39,624,641...39,651,867 		JBrowse link
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:225122 PMID:15689546 PMID:15714323 PMID:20738730 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B treatment IDA associated with Morphine Dependence RGD PMID:25604667 RGD:13514096 NCBI chr10:83,843,948...83,853,063
Ensembl chr10:83,347,731...83,356,775 		JBrowse link
G Prkg2 protein kinase cGMP-dependent 2 severity IEP RGD PMID:23113297 RGD:401938657 NCBI chr14:10,864,020...10,972,617
Ensembl chr14:10,559,882...10,666,888 		JBrowse link
G Prl prolactin treatment ISO CTD Direct Evidence: marker/mechanism
associated with opiate dependence		 CTD
RGD		 PMID:9037573 PMID:6932063 RGD:401959329 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Ptger3 prostaglandin E receptor 3 treatment IMP RGD PMID:10708732 RGD:10043351 NCBI chr 2:249,264,985...249,409,966
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
G Ren renin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28415 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:44,796,091...44,807,489 		JBrowse link
G Rhoa ras homolog family member A ISO CTD Direct Evidence: marker/mechanism CTD PMID:30158054 NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Runx2 RUNX family transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30158054 NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Slc6a1 solute carrier family 6 member 1 IEP
ISO		 protein:increased expression:cerebral cortex
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:14598306 PMID:15976529 RGD:1643202 NCBI chr 4:149,004,447...149,037,840
Ensembl chr 4:147,466,965...147,482,293 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17000009 NCBI chr10:62,322,688...62,357,060
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Smad1 SMAD family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30158054 NCBI chr19:45,417,430...45,477,962
Ensembl chr19:28,513,131...28,573,651 		JBrowse link
G Smad5 SMAD family member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30158054 NCBI chr17:7,867,640...7,896,983
Ensembl chr17:7,864,720...7,891,634 		JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30158054 NCBI chr12:14,748,717...14,840,273
Ensembl chr12:9,635,025...9,726,519 		JBrowse link
G Tacr1 tachykinin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7692360 NCBI chr 4:116,478,617...116,647,492
Ensembl chr 4:114,920,844...115,089,733 		JBrowse link
G Th tyrosine hydroxylase IEP protein:increased serine phosphorylation:brainstem (rat) RGD PMID:20973778 RGD:5128830 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19134
    Chemically-Induced Disorders 1458
      substance-related disorder 793
        Alcohol-Related Disorders + 492
        Cocaine-Related Disorders + 160
        Inhalant Abuse 1
        Narcotic-Related Disorders + 109
        neonatal abstinence syndrome 6
        phencyclidine abuse 7
        substance abuse + 277
        substance dependence + 207
        substance-induced psychosis + 134
        withdrawal disorder + 112
Path 2
Term Annotations click to browse term
  disease 19134
    disease of anatomical entity 18447
      nervous system disease 14354
        central nervous system disease 12627
          brain disease 11847
            disease of mental health 8447
              substance-related disorder 793
                Alcohol-Related Disorders + 492
                Cocaine-Related Disorders + 160
                Inhalant Abuse 1
                Narcotic-Related Disorders + 109
                neonatal abstinence syndrome 6
                phencyclidine abuse 7
                substance abuse + 277
                substance dependence + 207
                substance-induced psychosis + 134
                withdrawal disorder + 112
paths to the root