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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:acinar cell carcinoma
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Accession:DOID:3025 term browser browse the term
Definition:A carcinoma that has_material_basis_in abnormally proliferating cells, derives_from spindle cells and/or derives_from giant cells. (DO)
Synonyms:exact_synonym: Acinar Cell Adenocarcinoma;   Acinar Cell Adenocarcinomas;   Acinar Cell Carcinomas;   Acinic Cell Adenocarcinoma;   Acinic Cell Adenocarcinomas;   Acinic Cell Carcinoma;   Acinic Cell Carcinomas;   Acinic Cell Tumor;   acinar carcinoma;   acinar carcinomas;   acinic cell tumors;   serous acinar adenoma
 narrow_synonym: Parotid Gland Acinic Cell Carcinoma;   Salivary Gland Acinic Cell Carcinoma
 primary_id: MESH:D018267
 xref: EFO:0000216;   EFO:1000458;   EFO:1000513;   GARD:8568;   ICDO:8550/3;   NCI:C3768
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
acinar cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway ISO DNA:mutations (human) RGD PMID:11891193 RGD:2317200 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
pancreatic acinar cell adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO DNA:missense mutation, gene fusions:multiple (human) RGD PMID:25266736 RGD:13462041 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase disease_progression IEP RGD PMID:8569183 RGD:150523792 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19134
    disease of cellular proliferation 7888
      cancer 5717
        cell type cancer 3782
          carcinoma 3274
            adenocarcinoma 1700
              acinar cell carcinoma 3
                acinic cell breast carcinoma 0
                pancreatic acinar cell adenocarcinoma + 2
paths to the root