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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:invasive ductal carcinoma
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Accession:DOID:3008 term browser browse the term
Definition:A breast ductal carcinoma that is characterized by infiltration into the fibrous or fatty tissue of the breast outside of the duct where it originated. (DO)
Synonyms:exact_synonym: ductal adenocarcinoma;   infiltrating duct carcinoma;   infiltrating duct carcinoma of breast;   infiltrating duct carcinomas;   infiltrating ductal carcinoma of breast;   invasive breast ductal carcinoma;   invasive ductal breast cancer;   invasive ductal carcinoma, NST;   invasive ductal carcinoma, not otherwise specified;   mammary ductal carcinoma;   mammary ductal carcinomas
 narrow_synonym: invasive breast ductal and lobular carcinoma
 primary_id: MESH:D018270
 xref: EFO:0000184;   EFO:0000186;   EFO:0000552;   NCI:C4017;   NCI:C4194
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
invasive ductal carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 disease_progression ISO RGD PMID:19879256 RGD:2315549 NCBI chr 7:79,497,536...79,706,277
Ensembl chr 7:93,147,950...93,243,238 		JBrowse link
G ABCC9 ATP binding cassette subfamily C member 9 ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr12:64,357,176...64,500,358
Ensembl chr12:66,960,888...67,102,496 		JBrowse link
G ADAM28 ADAM metallopeptidase domain 28 disease_progression ISO DNA:hypermethylation:CpG island RGD PMID:19549921 RGD:153298911 NCBI chr 8:23,549,892...23,623,859
Ensembl chr 8:20,474,029...20,540,692 		JBrowse link
G ADGRB1 adhesion G protein-coupled receptor B1 disease_progression ISO RGD PMID:25376607 RGD:13831358 NCBI chr 8:139,154,065...139,251,115
Ensembl chr 8:142,220,827...142,301,070 		JBrowse link
G AGER advanced glycosylation end-product specific receptor ISO protein:increased expression:breast RGD PMID:22366088 RGD:8695990 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO DNA:missense mutation:p.E17K (human) RGD PMID:18392055 RGD:13209138 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr10:42,461,398...42,531,576
Ensembl chr10:45,639,946...45,710,016 		JBrowse link
G AMFR autocrine motility factor receptor ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr16:36,647,792...36,711,782
Ensembl chr16:55,780,633...55,843,744 		JBrowse link
G ANXA1 annexin A1 treatment ISO RGD PMID:18776816 PMID:19171478 RGD:7421535 RGD:7421560 NCBI chr 9:51,647,404...51,665,990
Ensembl chr 9:71,929,728...71,948,779 		JBrowse link
G ANXA2 annexin A2 treatment ISO RGD PMID:19171478 RGD:7421560 NCBI chr15:39,322,303...39,371,565
Ensembl chr15:57,625,425...57,674,250 		JBrowse link
G AR androgen receptor severity ISO RGD PMID:16075292 RGD:1643344 NCBI chr  X:56,722,828...56,909,004
Ensembl chr  X:66,791,081...66,969,357 		JBrowse link
G AREG amphiregulin ISO RGD PMID:11523048 RGD:2292660 NCBI chr 4:49,737,191...49,747,013
Ensembl chr 4:55,570,299...55,580,142 		JBrowse link
G ARPC2 actin related protein 2/3 complex subunit 2 ISO protein:increased expression:breast (human) RGD PMID:21136934 RGD:11049179 NCBI chr2B:105,478,035...105,513,665
Ensembl chr2B:224,076,356...224,111,643 		JBrowse link
G ATF4 activating transcription factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14604972 NCBI chr22:20,426,743...20,428,892
Ensembl chr22:38,248,094...38,249,249 		JBrowse link
G AURKA aurora kinase A ISO protein:altered expression RGD PMID:14693746 RGD:1643348 NCBI chr20:52,707,757...52,730,579
Ensembl chr20:53,994,881...54,017,339 		JBrowse link
G BAG1 BAG cochaperone 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19066611 NCBI chr 9:33,033,267...33,043,013
Ensembl chr 9:33,841,449...33,851,167 		JBrowse link
G BRCA1 BRCA1 DNA repair associated ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal | ClinVar Annotator: match by term: Infiltrating duct carcinoma of breast ClinVar PMID:7493024 PMID:9063749 PMID:10196379 PMID:11179017 PMID:11400546 More... NCBI chr17:14,197,946...14,279,064
Ensembl chr17:14,428,526...14,506,815 		JBrowse link
G BRCA2 BRCA2 DNA repair associated ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal | ClinVar Annotator: match by term: Infiltrating duct carcinoma of breast | ClinVar Annotator: match by term: Invasive Ductal Carcinoma, Not Otherwise Specified ClinVar PMID:11062481 PMID:11927503 PMID:14555511 PMID:14973102 PMID:15145354 More... NCBI chr13:13,574,422...13,658,967
Ensembl chr13:32,010,066...32,091,332 		JBrowse link
G BRMS1 BRMS1 transcriptional repressor and anoikis regulator disease_progression ISO mRNA, protein:decreased expression:brain metastases:10-fold lower expression in metastases vs primary tumors RGD PMID:15592684 RGD:2289400 NCBI chr11:61,703,021...61,710,784
Ensembl chr11:65,028,407...65,036,163 		JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar PMID:28492532 NCBI chr12:2,166,672...2,817,827
Ensembl chr12:2,114,140...2,744,826 		JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar PMID:26467025 PMID:27148582 PMID:28492532 Ensembl chr16:1,195,364...1,222,917 JBrowse link
G CAV1 caveolin 1 no_association ISO DNA:missense mutation: :p.P132L (human) RGD PMID:21909981 RGD:8661779 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655 		JBrowse link
G CCDC180 coiled-coil domain containing 180 ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr 9:68,380,995...68,467,787
Ensembl chr 9:96,503,785...96,589,386 		JBrowse link
G CCDC71L coiled-coil domain containing 71 like ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr 7:98,630,275...98,634,657 JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO protein:increased expression:breast, ductal carcinoma (human) RGD PMID:18790652 RGD:4891911 NCBI chr17:20,915,198...20,923,530
Ensembl chr17:21,210,798...21,219,172 		JBrowse link
G CCND3 cyclin D3 severity ISO protein:increased expression:breast RGD PMID:11329139 RGD:2316016 NCBI chr 6:41,518,421...41,630,103
Ensembl chr 6:42,820,569...42,827,498 		JBrowse link
G CD274 CD274 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:16611412 NCBI chr 9:5,269,270...5,289,629
Ensembl chr 9:5,454,391...5,474,402 		JBrowse link
G CD44 CD44 molecule (IN blood group) disease_progression ISO protein:increased expression:breast RGD PMID:17059779 RGD:2289352 NCBI chr11:35,110,732...35,258,238
Ensembl chr11:34,985,634...35,079,009 		JBrowse link
G CDH1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8557030 PMID:17660459 NCBI chr16:49,108,745...49,206,347
Ensembl chr16:68,502,584...68,596,488 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A ISO DNA:hypermethylation:promoter:breast, serum RGD PMID:17383681 RGD:2289677 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G CLDN4 claudin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19142967 Ensembl chr 7:80,983,832...80,984,461 JBrowse link
G CLU clusterin ISO RGD PMID:10934144 RGD:8699513 NCBI chr 8:26,867,973...26,884,838
Ensembl chr 8:24,070,053...24,083,523 		JBrowse link
G CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr10:95,942,366...96,009,729
Ensembl chr10:99,436,669...99,500,860 		JBrowse link
G CORO6 coronin 6 ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr17:27,151,620...27,159,795
Ensembl chr17:27,668,659...27,676,808 		JBrowse link
G CPAMD8 C3 and PZP like alpha-2-macroglobulin domain containing 8 ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr19:16,379,956...16,513,841
Ensembl chr19:17,359,534...17,487,791 		JBrowse link
G CPXM2 carboxypeptidase X, M14 family member 2 ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr10:120,302,984...120,449,022
Ensembl chr10:124,576,161...124,721,359 		JBrowse link
G CREB3 cAMP responsive element binding protein 3 ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr 9:35,583,351...35,587,870
Ensembl chr 9:36,385,867...36,390,540 		JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein disease_progression ISO protein:increased expression:breast RGD PMID:23686806 RGD:7488897 NCBI chr22:3,141,147...3,177,448
Ensembl chr22:19,632,359...19,668,858 		JBrowse link
G CSNK1E casein kinase 1 epsilon ISO DNA:mutation:CDS:multiple nonsynonymous mutations RGD PMID:14871824 RGD:2306813 NCBI chr22:19,202,599...19,229,344
Ensembl chr22:37,027,094...37,072,942 		JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 ISO DNA:mutation:CDS:multiple nonsynonymous mutations RGD PMID:14871824 RGD:2306813 NCBI chr 3:194,386,263...194,648,015
Ensembl chr 3:204,323,724...204,584,987 		JBrowse link
G EBAG9 estrogen receptor binding site associated antigen 9 ISO mRNA, protein:increased expression:breast RGD PMID:11742495 RGD:2289858 NCBI chr 8:106,190,208...106,216,402
Ensembl chr 8:108,335,590...108,361,475 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28235801 NCBI chr17:17,560,337...17,600,808
Ensembl chr17:17,777,434...17,805,862 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO RGD PMID:14532106 RGD:9588325 NCBI chr 7:140,536,962...140,613,104
Ensembl chr 7:153,017,590...153,059,726 		JBrowse link
G FGD1 FYVE, RhoGEF and PH domain containing 1 ISO protein:increased expression:breast (human) RGD PMID:19141649 RGD:11554027 NCBI chr  X:46,648,765...46,699,444
Ensembl chr  X:54,880,513...54,930,672 		JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase ISO DNA:loss of heterozygosity,hypermethylation:breast:LOH in 8/40 tumors (20%), hypermethylation in 22/46 tumors (48%), significant positive association found (p=0.04) RGD PMID:12231533 RGD:2289894 NCBI chr 3:59,670,777...61,177,974 JBrowse link
G FOXC1 forkhead box C1 disease_progression ISO RGD PMID:21424368 RGD:8662363 NCBI chr 6:1,429,051...1,433,180 JBrowse link
G FUBP1 far upstream element binding protein 1 ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr 1:77,162,675...77,198,486 JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO protein:altered localization:nucleus RGD PMID:16080559 RGD:2306227 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885 		JBrowse link
G HOXB7 homeobox B7 ISO mRNA:increased expression:breast epithelium (human) RGD PMID:17018609 RGD:10402178 NCBI chr17:8,925,717...8,929,523
Ensembl chr17:9,110,864...9,114,639 		JBrowse link
G HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 severity ISO protein:decreased expression:ductal breast carcinoma (human) RGD PMID:10682658 RGD:4890946 NCBI chr17:14,760,856...14,763,584
Ensembl chr17:14,986,814...14,988,820 		JBrowse link
G HTRA2 HtrA serine peptidase 2 ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr2A:74,596,020...74,599,790
Ensembl chr2A:76,102,240...76,106,152 		JBrowse link
G IL13 interleukin 13 ISO protein:increased expression:breast RGD PMID:22135852 RGD:8549515 NCBI chr 5:128,073,863...128,078,453
Ensembl chr 5:134,235,788...134,240,548 		JBrowse link
G IL18 interleukin 18 ISO protein:increased expression:breast RGD PMID:21263407 RGD:8655888 NCBI chr11:107,024,376...107,045,194
Ensembl chr11:110,867,586...110,888,371 		JBrowse link
G INHA inhibin subunit alpha ISO protein:decreased expression:tumor:significantly lower in invasive, infiltrating and metastatic tumors than in ductal carcinoma in situ tumors RGD PMID:15583806 RGD:2290390 NCBI chr2B:106,828,948...106,832,993
Ensembl chr2B:225,419,176...225,423,386 		JBrowse link
G JUP junction plakoglobin disease_progression ISO protein:decreased expression:tumor:associated with higher Robinson grade (p=0.016) and lymph node metastases (p=0.012) RGD PMID:16610682 RGD:2291882 NCBI chr17:15,527,115...15,559,251
Ensembl chr17:15,747,163...15,777,479 		JBrowse link
G KDM4E lysine demethylase 4E ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr11:90,039,540...90,041,341
Ensembl chr11:93,561,957...93,563,477 		JBrowse link
G KISS1 KiSS-1 metastasis suppressor disease_progression ISO mRNA, protein:decreased expression:brain metastases:10-fold lower expression in metastases vs primary tumors RGD PMID:15592684 RGD:2289400
G KIT KIT proto-oncogene, receptor tyrosine kinase severity ISO protein:decreased expression:tumor:loss of expression associated with lymph node metastasis (p<0.0001) and reduced disease-free survival (p=0.0041) RGD PMID:16721362 RGD:2292426 NCBI chr 4:69,199,543...69,282,323
Ensembl chr 4:75,761,946...75,844,473 		JBrowse link
G KNDC1 kinase non-catalytic C-lobe domain containing 1 ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar Ensembl chr10:134,068,936...134,132,964 JBrowse link
G LRAT lecithin retinol acyltransferase ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr 4:147,110,568...147,119,706
Ensembl chr 4:158,928,607...158,937,747 		JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 disease_progression ISO mRNA, protein:decreased expression:brain metastases:10-fold lower expression in metastases vs primary tumors RGD PMID:15592684 RGD:2289400 NCBI chr17:39,497,105...39,622,331
Ensembl chr17:44,248,857...44,359,909 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase severity ISO protein:increased expression:tumor (human) RGD PMID:10590366 RGD:2317607 NCBI chr 7:108,646,278...108,772,238
Ensembl chr 7:121,365,438...121,468,159 		JBrowse link
G MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr11:12,278,223...12,431,027
Ensembl chr11:12,022,093...12,123,855 		JBrowse link
G MIER3 MIER family member 3 ISO mRNA:increased expression:breast RGD PMID:22993404 RGD:407571689 NCBI chr 5:57,060,314...57,092,948
Ensembl chr 5:58,689,857...58,722,146 		JBrowse link
G MMP13 matrix metallopeptidase 13 disease_progression ISO mRNA, protein:increased expression:tumor:associated with microinvasion during the transition from ductal carcinoma in situ to invasive carcinoma, also expressed in all invasive ductal carcinomas tested RGD PMID:11585740 RGD:2293606 NCBI chr11:97,890,811...97,902,778
Ensembl chr11:101,377,001...101,387,679 		JBrowse link
G NCOA4 nuclear receptor coactivator 4 ISO protein:decreased expression:breast RGD PMID:11561770 RGD:2293536 NCBI chr10:43,159,014...43,184,558
Ensembl chr10:46,420,952...46,443,223 		JBrowse link
G NEFL neurofilament light chain ISO DNA:loss of heterozygosity RGD PMID:8814452 RGD:2298999 NCBI chr 8:24,218,510...24,224,627
Ensembl chr 8:21,134,533...21,140,694 		JBrowse link
G NHERF1 NHERF family PDZ scaffold protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28235801 NCBI chr17:68,694,468...68,715,157
Ensembl chr17:74,250,406...74,271,234 		JBrowse link
G NOTCH3 notch receptor 3 ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr19:14,692,571...14,733,758
Ensembl chr19:15,678,674...15,715,080 		JBrowse link
G NTRK3 neurotrophic receptor tyrosine kinase 3 ISO mRNA,protein:increased expression:breast: RGD PMID:20802235 RGD:150520014 NCBI chr15:66,566,219...66,953,279
Ensembl chr15:85,776,832...86,157,204 		JBrowse link
G NTS neurotensin ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr12:83,402,313...83,410,356
Ensembl chr12:86,640,720...86,648,745 		JBrowse link
G PCNA proliferating cell nuclear antigen severity ISO RGD PMID:8102204 RGD:2315014 NCBI chr20:5,134,930...5,146,603
Ensembl chr20:4,927,731...4,939,440 		JBrowse link
G PHF24 PHD finger protein 24 ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr 9:34,735,800...34,829,555
Ensembl chr 9:35,611,517...35,635,964 		JBrowse link
G PML PML nuclear body scaffold ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr15:52,903,874...52,955,151
Ensembl chr15:71,658,884...71,710,883 		JBrowse link
G PRKCI protein kinase C iota disease_progression ISO protein:increased expression, altered localization:breast, cytoplasm RGD PMID:18538170 RGD:2314932 NCBI chr 3:167,237,093...167,320,522
Ensembl chr 3:175,426,774...175,510,072 		JBrowse link
G PTGER1 prostaglandin E receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11751431 NCBI chr19:14,035,876...14,038,812 JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21153458 NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519 		JBrowse link
G RAD50 RAD50 double strand break repair protein ISO protein:decreased expression:tumor:reduced in 28% vs adjacent or independent normal breast tissue RGD PMID:14511253 RGD:2300250 NCBI chr 5:127,972,630...128,059,911
Ensembl chr 5:134,134,495...134,222,261 		JBrowse link
G RAD54L RAD54 like ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar PMID:10362365 NCBI chr 1:45,549,586...45,581,711
Ensembl chr 1:46,905,598...46,936,259 		JBrowse link
G RNF212 ring finger protein 212 ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr 4:1,167,176...1,259,080
Ensembl chr 4:1,102,342...1,146,153 		JBrowse link
G RP1 RP1 axonemal microtubule associated ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr 8:50,979,412...51,311,431
Ensembl chr 8:48,419,033...48,583,879
Ensembl chr 8:48,419,033...48,583,879 		JBrowse link
G RRP1 ribosomal RNA processing 1 ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr21:30,045,143...30,061,243
Ensembl chr21:43,343,786...43,358,401 		JBrowse link
G RUNX3 RUNX family transcription factor 3 disease_progression ISO DNA:promoter:hypermethylation protein:mislocalization RGD PMID:18256927 RGD:2302557 NCBI chr 1:24,097,321...24,164,065
Ensembl chr 1:25,073,134...25,137,335 		JBrowse link
G SERPINB5 serpin family B member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19944674 NCBI chr18:56,836,403...56,864,533
Ensembl chr18:60,148,552...60,176,624 		JBrowse link
G SLITRK6 SLIT and NTRK like family member 6 ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr13:66,990,025...67,003,900
Ensembl chr13:86,161,905...86,164,430 		JBrowse link
G SMAD4 SMAD family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20565773 NCBI chr18:44,402,112...44,456,779
Ensembl chr18:47,764,568...47,797,359 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 ISO mRNA:increased expression:breast RGD PMID:12888825 RGD:2298909 NCBI chr16:10,196,432...10,198,205 JBrowse link
G SOCS2 suppressor of cytokine signaling 2 ISO mRNA:increased expression:breast RGD PMID:12888825 RGD:2298909 NCBI chr12:91,115,319...91,134,191
Ensembl chr12:94,514,455...94,520,748 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 ISO mRNA:increased expression:breast RGD PMID:12888825 RGD:2298909 NCBI chr17:72,433,206...72,436,500
Ensembl chr17:77,983,389...77,984,066 		JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23964924 NCBI chr 6:157,562,814...157,610,155
Ensembl chr 6:162,576,082...162,589,960 		JBrowse link
G SPEN spen family transcriptional repressor ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr 1:14,987,415...15,079,477
Ensembl chr 1:16,004,473...16,072,585 		JBrowse link
G SYT6 synaptotagmin 6 ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr 1:88,397,809...88,467,493
Ensembl chr 1:123,452,889...123,514,795 		JBrowse link
G TMBIM6 transmembrane BAX inhibitor motif containing 6 disease_progression ISO RGD PMID:17054309 RGD:2291958 NCBI chr12:38,986,844...39,010,307
Ensembl chr12:39,879,951...39,902,303 		JBrowse link
G TSPAN8 tetraspanin 8 ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr12:68,653,209...68,686,565
Ensembl chr12:71,417,577...71,450,873 		JBrowse link
G TSPEAR thrombospondin type laminin G domain and EAR repeats ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar PMID:25741868 NCBI chr21:30,791,051...31,005,330
Ensembl chr21:44,087,591...44,299,041 		JBrowse link
G UBR5 ubiquitin protein ligase E3 component n-recognin 5 ISO DNA:mutation:CDS:multiple nonsynonymous mutations RGD PMID:14871824 RGD:2306813 NCBI chr 8:98,904,557...99,064,121
Ensembl chr 8:101,067,435...101,224,913 		JBrowse link
G VEGFC vascular endothelial growth factor C disease_progression ISO RGD PMID:19885590 RGD:2315471 NCBI chr 4:168,870,941...168,999,160
Ensembl chr 4:181,104,737...181,236,030 		JBrowse link
G WIF1 WNT inhibitory factor 1 ISO protein:decreased expression:breast RGD PMID:14517837 RGD:727214 NCBI chr12:23,795,280...23,866,666
Ensembl chr12:24,299,351...24,370,807 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 susceptibility ISO DNA:polymorphism: :p.R399Q RGD PMID:18752184 RGD:2302569 NCBI chr19:40,485,052...40,522,188
Ensembl chr19:49,094,014...49,125,520 		JBrowse link
G YEATS2 YEATS domain containing 2 ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr 3:180,736,213...180,847,545
Ensembl chr 3:188,903,615...189,016,942 		JBrowse link
G ZDBF2 zinc finger DBF-type containing 2 ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr2B:93,516,875...93,556,652
Ensembl chr2B:211,645,765...211,685,047 		JBrowse link
G ZNF420 zinc finger protein 420 ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr19:34,039,699...34,093,881 JBrowse link
G ZNF473 zinc finger protein 473 ISO ClinVar Annotator: match by term: Breast cancer, invasive ductal ClinVar NCBI chr19:47,038,131...47,061,202
Ensembl chr19:55,953,766...55,980,946 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15835
    disease of cellular proliferation 7465
      Neoplasms by Site 6921
        Breast Neoplasms 1401
          breast cancer 889
            breast carcinoma 291
              breast ductal carcinoma 111
                invasive ductal carcinoma 103
                  breast pleomorphic carcinoma 0
Path 2
Term Annotations click to browse term
  disease 15835
    Pathological Conditions, Signs and Symptoms 12339
      Signs and Symptoms 10388
        Neurologic Manifestations 10069
          sensory system disease 7070
            skin disease 4133
              breast disease 1413
                Breast Neoplasms 1401
                  breast cancer 889
                    breast carcinoma 291
                      breast ductal carcinoma 111
                        invasive ductal carcinoma 103
                          breast pleomorphic carcinoma 0
paths to the root