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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:idiopathic interstitial pneumonia
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Accession:DOID:2797 term browser browse the term
Definition:A pneumonia located_in the lung parenchyma of unknown cause. (DO)
Synonyms:exact_synonym: diffuse idiopathic pulmonary fibrosis;   idiopathic fibrosing alveolitis;   idiopathic interstitial pneumonias
 primary_id: MESH:D054988
 xref: ICD10CM:J84.11
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:
idiopathic interstitial pneumonia term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl6 C-X-C motif chemokine ligand 6 ISO associated with Scleroderma, Diffuse
protein:increased expression:serum
RGD PMID:18432520 PMID:16085216 RGD:5135258, RGD:5135260 NCBI chr14:17,310,790...17,312,250 JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO protein:increased expression:lung, alveolar macrophage (human) RGD PMID:19218648 RGD:4145518 NCBI chr 8:27,829,688...27,841,618 JBrowse link
G Il6 interleukin 6 IEP protein:increased expression:bronchoalveolar lavage (rat) RGD PMID:10988147 RGD:11062092 NCBI chr 4:5,889,999...5,894,575 JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 ISO protein:increased expression:hyperplastic lung epithelium, alveolus (human) RGD PMID:20718723 RGD:6893300 NCBI chr 8:19,768,375...19,777,862 JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO RGD PMID:21444868 RGD:7245946 NCBI chr 5:164,167,985...164,277,438 JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 ISO protein:increased expression:serum RGD PMID:15467329 RGD:5144148 NCBI chr 1:215,406,138...215,409,686 JBrowse link
G Tert telomerase reverse transcriptase ISO ClinVar Annotator: match by term: idiopathic fibrosing alveolitis ClinVar PMID:9536098 PMID:15814878 PMID:15885610 PMID:16247010 PMID:17460043 More... NCBI chr 1:29,637,213...29,659,561 JBrowse link
cryptogenic organizing pneumonia term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfrsf1a TNF receptor superfamily member 1A ISO protein:increased expression:lung, macrophage (human) RGD PMID:21144722 RGD:5131112 NCBI chr 4:159,837,119...159,849,817 JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO protein:increased expression:lung, lymphocyte (human) RGD PMID:21144722 RGD:5131112 NCBI chr 5:157,070,642...157,104,216 JBrowse link
desquamative interstitial pneumonia term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sftpc surfactant protein C ISS OMIM:263000 MouseDO NCBI chr15:45,596,565...45,599,615 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19139
    Pathological Conditions, Signs and Symptoms 13623
      Pathologic Processes 8325
        Inflammation 2843
          pneumonia 228
            idiopathic interstitial pneumonia 10
              acute interstitial pneumonia 0
              cryptogenic organizing pneumonia 2
              desquamative interstitial pneumonia 1
              lymphoid interstitial pneumonia 0
              nonspecific interstitial pneumonia 0
Path 2
Term Annotations click to browse term
  disease 19139
    disease of anatomical entity 18450
      respiratory system disease 5242
        lower respiratory tract disease 2354
          lung disease 2315
            pneumonia 228
              idiopathic interstitial pneumonia 10
                acute interstitial pneumonia 0
                cryptogenic organizing pneumonia 2
                desquamative interstitial pneumonia 1
                lymphoid interstitial pneumonia 0
                nonspecific interstitial pneumonia 0
paths to the root