Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:renovascular hypertension
go back to main search page
Accession:DOID:1591 term browser browse the term
Definition:Hypertension due to RENAL ARTERY OBSTRUCTION or compression.
Synonyms:exact_synonym: Goldblatt Hypertension;   Goldblatt Syndrome;   renal vascular hypertension
 primary_id: MESH:D006978
 xref: EFO:1001153;   ICD10CM:I15.0;   NCI:C85044
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
renovascular hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme treatment IEP
IDA 		RGD PMID:22342460 PMID:20630208 RGD:6893471, RGD:8157609 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942 		JBrowse link
G Adm adrenomedullin ISO protein:increased expression:plasma RGD PMID:15284680 RGD:1625303 NCBI chr 1:174,164,178...174,182,372
Ensembl chr 1:174,178,773...174,182,371 		JBrowse link
G Adrb1 adrenoceptor beta 1 IMP
IDA 		RGD PMID:17278011 PMID:15592645 RGD:7241568, RGD:7241580 NCBI chr 1:265,777,103...265,780,114
Ensembl chr 1:265,766,079...265,849,237 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a IMP
IEP 		mRNA:decreased expression:kidney: RGD PMID:21326341 PMID:9644212 PMID:16796846 RGD:5129177, RGD:10047119, RGD:5147455 NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660 		JBrowse link
G Agtr1b angiotensin II receptor, type 1b treatment IEP mRNA:increased expression:kidney: RGD PMID:9644212 RGD:10047119 NCBI chr 2:102,844,969...102,920,232
Ensembl chr 2:104,773,930...104,849,310 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 IDA
IMP 		RGD PMID:21189405 PMID:18158356 RGD:6903867, RGD:6903868 NCBI chr  X:116,914,320...116,918,504
Ensembl chr  X:116,913,656...116,918,745 		JBrowse link
G Avpr1a arginine vasopressin receptor 1A IEP mRNA:altered expression:brain RGD PMID:15613739 RGD:2300323 NCBI chr 7:59,999,743...60,003,667
Ensembl chr 7:59,999,738...60,003,837 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta treatment IEP RGD PMID:26619200 RGD:401940196 NCBI chr 2:217,698,324...217,961,898
Ensembl chr 2:217,698,551...217,960,276 		JBrowse link
G Ccnd2 cyclin D2 IEP protein:increased expression:left ventricle: RGD PMID:26300251 RGD:151664604 NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:161,653,048...161,680,301
Ensembl chr 4:161,653,048...161,680,301 		JBrowse link
G Cma1 chymase 1 IEP protein:increased activity:kidney (rat) RGD PMID:15869764 RGD:1581745 NCBI chr15:29,417,451...29,420,233
Ensembl chr15:33,387,351...33,390,133 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 IDA RGD PMID:17062848 RGD:2311383 NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261 		JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 IDA RGD PMID:17062848 RGD:2311383 NCBI chr  X:70,884,293...70,886,944
Ensembl chr  X:70,883,958...70,886,871 		JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A treatment IEP RGD PMID:26619200 RGD:401940196 NCBI chr11:47,360,824...47,479,033
Ensembl chr11:47,360,850...47,479,033 		JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 IEP mRNA:increased expression:heart left ventricle RGD PMID:12708758 RGD:10755511 NCBI chr 1:174,616,102...174,628,252
Ensembl chr 1:174,616,103...174,628,252 		JBrowse link
G Fn1 fibronectin 1 IDA RGD PMID:17324142 RGD:7205461 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase treatment IEP RGD PMID:22684021 RGD:10449172 NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:157,352,373...157,372,144 		JBrowse link
G Gja1 gap junction protein, alpha 1 IEP RGD PMID:11422751 RGD:7207851 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689 		JBrowse link
G Gja5 gap junction protein, alpha 5 IEP RGD PMID:11422751 RGD:7207851 NCBI chr 2:187,291,227...187,310,770
Ensembl chr 2:187,234,674...187,318,512 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO protein:increased expression:urine: RGD PMID:22923545 RGD:7245500 NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,619,897...31,653,268 		JBrowse link
G Hdac8 histone deacetylase 8 treatment IEP RGD PMID:27673327 RGD:13208809 NCBI chr  X:71,425,240...71,632,865
Ensembl chr  X:71,394,928...71,632,865 		JBrowse link
G Lama2 laminin subunit alpha 2 IEP mRNA:decreased expression:heart RGD PMID:10773239 RGD:1600206 NCBI chr 1:19,492,126...20,140,056
Ensembl chr 1:19,244,599...20,140,056 		JBrowse link
G Lcn2 lipocalin 2 ISO protein:increased expression:urine,plasma RGD PMID:22923545 RGD:7245500 NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:36,078,436...36,081,842 		JBrowse link
G Mpo myeloperoxidase IEP protein:increased activity:heart, brain, kidney RGD PMID:19549002 RGD:7174698 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Nos1 nitric oxide synthase 1 IEP RGD PMID:16788145 RGD:1642130 NCBI chr12:44,276,011...44,456,371
Ensembl chr12:44,287,614...44,371,837 		JBrowse link
G Nos3 nitric oxide synthase 3 ISO CTD Direct Evidence: therapeutic CTD PMID:18641695 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664 		JBrowse link
G Pdgfa platelet derived growth factor subunit A IEP mRNA:increased expression:vascular associated smooth muscle cell RGD PMID:17439406 RGD:2289672 NCBI chr12:20,759,366...20,780,337
Ensembl chr12:20,754,208...20,780,322 		JBrowse link
G Prl prolactin IEP protein:increased expression:plasma RGD PMID:17316702 RGD:1642574 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217 		JBrowse link
G Ptger3 prostaglandin E receptor 3 IEP protein:increased expression:kidney (rat) RGD PMID:16788145 RGD:1642130 NCBI chr 2:249,264,985...249,409,966
Ensembl chr 2:249,264,985...249,409,846 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 IMP RGD PMID:17766473 RGD:2300258 NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:39,981,415...40,002,990 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IEP protein:increased expression:nucleus, kidney RGD PMID:18032469 RGD:2298840 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Ren renin ISO mRNA:increased expression:renal cortex (mouse)
protein:increased activity:blood plasma (human) 		RGD PMID:22378822 PMID:2240003 RGD:6892688, RGD:125097504 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543 		JBrowse link
G Slc9a1 solute carrier family 9 member A1 treatment IEP RGD PMID:12218313 RGD:727424 NCBI chr 5:150,859,412...150,913,525
Ensembl chr 5:150,860,228...150,913,517 		JBrowse link
G Slc9a3 solute carrier family 9 member A3 treatment IEP RGD PMID:12218313 RGD:727424 NCBI chr 1:30,953,215...30,996,209
Ensembl chr 1:30,953,216...30,996,002 		JBrowse link
G Spp1 secreted phosphoprotein 1 IDA RGD PMID:12620700 RGD:1581326 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820 		JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 treatment IEP RGD PMID:26619200 RGD:401940196 NCBI chr10:73,335,519...73,342,549
Ensembl chr10:73,336,422...73,342,548 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19167
    disease of anatomical entity 18473
      Urogenital Diseases 5238
        urinary system disease 2590
          kidney disease 2335
            renal hypertension 98
              renovascular hypertension 36
Path 2
Term Annotations click to browse term
  disease 19167
    disease of anatomical entity 18473
      cardiovascular system disease 5558
        vascular disease 4039
          artery disease 2864
            hypertension 1632
              secondary hypertension 98
                renal hypertension 98
                  renovascular hypertension 36
paths to the root