RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Severe or complete loss of facial muscle motor function. This condition may result from central or peripheral lesions. Damage to CNS motor pathways from the cerebral cortex to the facial nuclei in the pons leads to facial weakness that generally spares the forehead muscles. FACIAL NERVE DISEASES generally results in generalized hemifacial weakness. NEUROMUSCULAR JUNCTION DISEASES and MUSCULAR DISEASES may also cause facial paralysis or paresis.
Synonyms:
exact_synonym:
Central Facial Paralysis; Facial Palsy; Facial Paralyses, Peripheral; Facial Paresis; Hemifacial Paralysis; Lower Motor Neuron Facial Palsy; Paralyses, Facial; Paralyses, Hemifacial; Pareses, Facial; central facial paralyses; facial palsies; peripheral facial paralysis; upper motor neuron facial palsy
ClinVar Annotator: match by term: Facial palsy, congenital, with ptosis and velopharyngeal dysfunction | ClinVar Annotator: match by term: TUBB6-related condition