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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:intracranial vasospasm
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Accession:DOID:13100 term browser browse the term
Definition:Constriction of arteries in the SKULL due to sudden, sharp, and often persistent smooth muscle contraction in blood vessels. Intracranial vasospasm results in reduced vessel lumen caliber, restricted blood flow to the brain, and BRAIN ISCHEMIA that may lead to hypoxic-ischemic brain injury (HYPOXIA-ISCHEMIA, BRAIN).
Synonyms:exact_synonym: Cerebral Angiospasm;   Cerebral Artery Spasm;   Cerebral Artery Spasms;   Cerebral Vasospasm;   Cerebral Vasospasms;   Cerebrovascular Spasm;   Cerebrovascular Spasms;   Intracranial Angiospasm;   Intracranial Angiospasms;   Intracranial Vascular Spasm;   Intracranial Vascular Spasms;   cerebral angiospasms;   intracranial vasospasms
 primary_id: MESH:D020301
 xref: EFO:1000994
For additional species annotation, visit the Alliance of Genome Resources.


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intracranial vasospasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 IEP associated with Subarachnoid Hemorrhage;mRNA, protein:increased expression:basilar artery RGD PMID:19401162 RGD:2306995 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Hmox1 heme oxygenase 1 treatment IMP
ISO		 associated with Subarachnoid Hemorrhage RGD PMID:19686725 PMID:14657544 PMID:21654696 RGD:4145300, RGD:1598406, RGD:10755572 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: therapeutic CTD PMID:19057314 PMID:29651748 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
G Ryr1 ryanodine receptor 1 ISO associated with Subarachnoid Hemorrhage; c.6178G>T(rs35364374)(human) RGD PMID:21503806 RGD:329811998 NCBI chr 1:84,292,578...84,423,824
Ensembl chr 1:84,292,578...84,423,812 		JBrowse link
G S100a1 S100 calcium binding protein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12186470 NCBI chr 2:175,993,922...175,998,765
Ensembl chr 2:175,993,922...175,999,544 		JBrowse link
G S100a4 S100 calcium-binding protein A4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12186470 NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254 		JBrowse link
G S100a6 S100 calcium binding protein A6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12186470 NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180 		JBrowse link
G S100b S100 calcium binding protein B ISO CTD Direct Evidence: marker/mechanism CTD PMID:12186470 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743 		JBrowse link
G Tnc tenascin C ISO associated with Subarachnoid Hemorrhage;protein:increased expression:serum RGD PMID:19589197 RGD:4889600 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19099
    disease of anatomical entity 18440
      cardiovascular system disease 5538
        vascular disease 4020
          cerebrovascular disease 1000
            intracranial vasospasm 9
Path 2
Term Annotations click to browse term
  disease 19099
    disease of anatomical entity 18440
      nervous system disease 14334
        central nervous system disease 12604
          brain disease 11833
            cerebrovascular disease 1000
              intracranial vasospasm 9
paths to the root