|
G |
Abat |
4-aminobutyrate aminotransferase |
|
IDA |
|
RGD |
PMID:1570022 |
RGD:1598531 |
NCBI chr10:7,503,351...7,599,474
|
|
G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17272743 |
|
NCBI chr10:1,022,041...1,162,431
|
|
G |
Abcc8 |
ATP binding cassette subfamily C member 8 |
|
ISO |
associated with obesity;DNA:polymorphism:exon: |
RGD |
PMID:11030411 |
RGD:737749 |
NCBI chr 1:105,734,992...105,816,272
|
|
G |
Abcc9 |
ATP binding cassette subfamily C member 9 |
|
IEP |
protein:decreased expression:aorta |
RGD |
PMID:15964031 PMID:18471810 |
RGD:1598644, RGD:2301909 |
NCBI chr 4:177,262,848...177,386,837
|
|
G |
Abo |
ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase |
susceptibility |
ISO |
associated with COVID-19; DNA:polymorphism:cds:allele A (human) |
RGD |
PMID:32379894 |
RGD:35668862 |
NCBI chr 3:10,162,087...10,182,835
|
|
G |
Ace |
angiotensin I converting enzyme |
susceptibility treatment |
ISO IEP IMP IDA |
DNA:polymorphism CTD Direct Evidence: marker/mechanism protein:increased activity:lung (rat) |
CTD RGD |
PMID:15773232 PMID:17473847 PMID:20237592 PMID:27847271 PMID:17283861 PMID:30127255 PMID:27325568 PMID:16203874 PMID:24342267 PMID:3006710 PMID:15118671 PMID:17392119 More...
|
RGD:1601114, RGD:401793709, RGD:40400899, RGD:1581743, RGD:11039415, RGD:8157611, RGD:1331525, RGD:1601113 |
NCBI chr10:91,410,129...91,430,246
|
|
G |
Ace2 |
angiotensin converting enzyme 2 |
treatment |
ISO IEP |
associated with Metabolic Syndrome X (MeSH:D024821) mRNA, protein:decreased expression:kidney (rat) CTD Direct Evidence: marker/mechanism|therapeutic mRNA, protein:decreased expression:aorta |
CTD RGD |
PMID:12075344 PMID:15833808 PMID:17473847 PMID:18391097 PMID:19221212 PMID:20559404 PMID:21859683 PMID:16459167 PMID:12075344 PMID:20854846 PMID:16788004 PMID:17345786 More...
|
RGD:1642828, RGD:629626, RGD:9685442, RGD:9685435, RGD:9685433 |
NCBI chr X:30,293,597...30,340,961
|
|
G |
Acsm3 |
acyl-CoA synthetase medium-chain family member 3 |
|
IAGP |
|
RGD |
PMID:8094726 PMID:8507454 |
RGD:61050, RGD:634023 |
NCBI chr 1:174,133,260...174,159,966
|
|
G |
Actc1 |
actin, alpha, cardiac muscle 1 |
|
IEP |
|
RGD |
PMID:16343576 |
RGD:1598724 |
NCBI chr 3:100,811,987...100,817,523
|
|
G |
Ada |
adenosine deaminase |
|
IDA |
|
RGD |
PMID:9605386 |
RGD:1624292 |
NCBI chr 3:152,398,745...152,422,854
|
|
G |
Adamts16 |
ADAM metallopeptidase with thrombospondin type 1 motif, 16 |
|
IMP |
|
RGD |
PMID:23185005 |
RGD:9685162 |
NCBI chr 1:32,430,436...32,562,481
|
|
G |
Adamts16em1Bj |
ADAM metallopeptidase with thrombospondin type 1 motif, 16; ZFN mutant1,Bj |
|
IMP |
|
RGD |
PMID:23185005 |
RGD:9685162 |
|
|
G |
Adcy5 |
adenylate cyclase 5 |
|
ISO IEP |
CTD Direct Evidence: marker/mechanism mRNA:decreased expression:heart left ventricle |
CTD RGD |
PMID:12717102 PMID:12717102 |
RGD:13464134 |
NCBI chr11:78,976,861...79,123,343
|
|
G |
Add1 |
adducin 1 |
|
IAGP ISO IDA |
CTD Direct Evidence: marker/mechanism DNA:polymorphism: :p.G460W (human) |
CTD RGD |
PMID:15773232 PMID:19199261 PMID:15474463 PMID:8543181 PMID:9149697 |
RGD:1302895, RGD:631736, RGD:1624953 |
NCBI chr14:76,108,643...76,167,267
|
|
G |
Add2 |
adducin 2 |
no_association |
IDA ISO |
DNA:SNP: :rs4852706 (human) DNA:polymorphism |
RGD GAD |
PMID:2059221 PMID:24652215 PMID:15118671 PMID:16497648 |
RGD:631712, RGD:10047131, RGD:1331525, RGD:1625293 |
NCBI chr 4:118,444,594...118,538,505
|
|
G |
Add3 |
adducin 3 |
|
IDA |
|
RGD |
PMID:12364392 |
RGD:704369 |
NCBI chr 1:262,152,722...262,260,504
|
|
G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:12860835 |
|
NCBI chr11:91,226,524...91,240,244
|
|
G |
Adm |
adrenomedullin |
|
IEP ISO |
mRNA, protein:increased expression:myocardium, aorta protein:increased expression:plasma |
RGD |
PMID:16450076 PMID:16625237 |
RGD:1625300, RGD:1625298 |
NCBI chr 1:174,164,178...174,182,372
|
|
G |
Adora1 |
adenosine A1 receptor |
treatment no_association |
IMP IDA ISO |
associated with diabetes mellitus, experimental |
RGD |
PMID:8998253 PMID:9597368 PMID:15257174 |
RGD:1625366, RGD:1625365, RGD:1625367 |
NCBI chr13:45,658,872...45,695,821
|
|
G |
Adora2a |
adenosine A2a receptor |
no_association |
ISO |
|
RGD GAD |
PMID:15257174 PMID:15118671 |
RGD:1625367, RGD:1331525 |
NCBI chr20:13,315,848...13,333,386
|
|
G |
Adra1a |
adrenoceptor alpha 1A |
|
IEP ISO |
mRNA:decreased expression:aorta |
RGD |
PMID:16371063 PMID:19011682 |
RGD:1625770, RGD:5688340 |
NCBI chr15:45,005,648...45,111,416
|
|
G |
Adra1b |
adrenoceptor alpha 1B |
|
ISO |
|
RGD |
PMID:16095979 |
RGD:1625771 |
NCBI chr10:28,255,025...28,373,418
|
|
G |
Adra2a |
adrenoceptor alpha 2A |
no_association |
ISO IEP |
DNA:polymorphism CTD Direct Evidence: marker/mechanism mRNA:decreased expression:adrenal gland medulla |
CTD RGD |
PMID:10694191 PMID:16636200 PMID:20691504 |
RGD:1625183, RGD:6480490 |
NCBI chr 1:263,066,780...263,069,580
|
|
G |
Adra2b |
adrenoceptor alpha 2B |
|
ISO IMP |
DNA:polymorphism (human) |
RGD |
PMID:18953403 PMID:17070424 |
RGD:2313541, RGD:2313548 |
NCBI chr 3:114,585,174...114,589,220
|
|
G |
Adrb1 |
adrenoceptor beta 1 |
|
IEP ISO |
protein:increased expression:aorta CTD Direct Evidence: marker/mechanism associated with Diabetes Mellitus, Type 2; |
CTD RGD |
PMID:9260993 PMID:10673262 PMID:19060223 PMID:20398560 |
RGD:5129127, RGD:7241549 |
NCBI chr 1:265,777,103...265,780,114
|
|
G |
Adrb2 |
adrenoceptor beta 2 |
no_association susceptibility |
ISO IEP |
DNA:polymorphisms: :p.R16G, p.Q27E DNA:polymorphisms: :pG16R, p.Q27E, p.T164I (human) associated with Kidney Failure, Chronic; DNA:SNP:cds:p.R16G (human) DNA:polymorphisms: :46A>G, 79C>G (human) |
RGD GAD |
PMID:17221209 PMID:16041242 PMID:15118671 PMID:2471888 PMID:20484896 PMID:20739939 PMID:16685203 More...
|
RGD:1601119, RGD:1578728, RGD:1331525, RGD:7175287, RGD:7175066, RGD:4144883, RGD:1601123 |
NCBI chr18:57,912,760...57,914,802
|
|
G |
Adrb3 |
adrenoceptor beta 3 |
|
ISO |
associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism: :p.W64R (human) |
RGD |
PMID:10981554 |
RGD:2313166 |
NCBI chr16:64,839,820...64,844,552
|
|
G |
Ager |
advanced glycosylation end product-specific receptor |
|
IEP ISO |
protein:increased expression:kidney CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:32147540 PMID:19018797 |
RGD:2325653 |
NCBI chr20:4,152,758...4,155,956
|
|
G |
Agt |
angiotensinogen |
treatment no_association susceptibility |
IEP ISO IDA IMP |
protein:increased expression:plasma, urine ClinVar Annotator: match by term: Hypertension CTD Direct Evidence: marker/mechanism|therapeutic DNA:polymorphisms: :p.T174M, p.M235T (human) DNA:polymorphisms: :-6G>A, p.M235T, p.T174M DNA:polymorphism: :p.M235T DNA:polymorphism:promoter:-20C>A (human) DNA:polymorphism: :p.M268T (human) |
ClinVar CTD RGD |
PMID:43064 PMID:1394429 PMID:1432030 PMID:1849535 PMID:1860718 PMID:1875449 PMID:2831029 PMID:2835134 PMID:3158602 PMID:6742791 PMID:7323490 PMID:7649545 PMID:7883995 PMID:8021468 PMID:8109997 PMID:8348146 PMID:8505092 PMID:8513325 PMID:8518804 PMID:9024144 PMID:9259580 PMID:9260993 PMID:9421481 PMID:9831339 PMID:10400907 PMID:10526905 PMID:11459117 PMID:11501062 PMID:12084390 PMID:12121858 PMID:12414515 PMID:12600921 PMID:12676074 PMID:14751847 PMID:15243307 PMID:15302986 PMID:15699457 PMID:15833808 PMID:15851630 PMID:16059745 PMID:16618834 PMID:16788141 PMID:16868307 PMID:17272743 PMID:17537837 PMID:17989111 PMID:18420994 PMID:18679781 PMID:18768397 PMID:18785976 PMID:18847324 PMID:19109942 PMID:19133994 PMID:19373235 PMID:19770776 PMID:19858406 PMID:19934029 PMID:20231528 PMID:20429690 PMID:20713914 PMID:20811386 PMID:20837116 PMID:20937366 PMID:21289285 PMID:21393355 PMID:21420289 PMID:21501650 PMID:22083158 PMID:22214961 PMID:22452651 PMID:22753205 PMID:22982863 PMID:24342267 PMID:24347665 PMID:24386282 PMID:24935938 PMID:24965170 PMID:25139994 PMID:25259750 PMID:25398788 PMID:25741868 PMID:25874449 PMID:26564064 PMID:26648693 PMID:26781276 PMID:27225954 PMID:27678262 PMID:27798352 PMID:27889505 PMID:28492532 PMID:29706566 PMID:30354818 PMID:30634441 PMID:31016362 PMID:31098697 PMID:31786979 PMID:21346625 PMID:33364953 PMID:24342267 PMID:21865264 PMID:19932924 PMID:9622148 PMID:19779471 PMID:15118671 PMID:1394429 PMID:12468106 PMID:16514903 PMID:17334527 PMID:16739866 PMID:17161775 PMID:21312059 More...
|
RGD:5129176, RGD:329956421, RGD:11039415, RGD:8549470, RGD:8549469, RGD:8549458, RGD:8548902, RGD:1331525, RGD:1300393, RGD:1358275, RGD:1601143, RGD:1601130, RGD:1601141, RGD:1601139, RGD:5129166 |
NCBI chr19:69,426,540...69,447,017
|
|
G |
Agtr1a |
angiotensin II receptor, type 1a |
treatment no_association susceptibility |
IMP IEP ISO |
associated with Sleep Apnea Syndromes CTD Direct Evidence: marker/mechanism mRNA:increased expression:aortic endothelial cell DNA:polymorphism:3' utr:1166A>C DNA:polymorphism:3' utr:g.1166A>C |
CTD RGD |
PMID:8952600 PMID:19047579 PMID:23603059 PMID:27292124 PMID:21040717 PMID:30127255 PMID:9622148 PMID:15118671 PMID:8181542 PMID:9456365 PMID:16519598 PMID:21346625 More...
|
RGD:5129169, RGD:401793709, RGD:8549458, RGD:1331525, RGD:5147456, RGD:1601152, RGD:1601148, RGD:5129176 |
NCBI chr17:34,383,397...34,435,523
|
|
G |
Agtr1b |
angiotensin II receptor, type 1b |
|
IEP ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:22728133 PMID:27847271 PMID:10994756 |
RGD:1598885 |
NCBI chr 2:104,774,005...104,849,262
|
|
G |
Agtr2 |
angiotensin II receptor, type 2 |
|
IMP ISO IEP |
associated with Sleep Apnea Syndromes CTD Direct Evidence: marker/mechanism mRNA, protein:decreased expression:kidney |
CTD RGD |
PMID:15710752 PMID:21040717 PMID:11924718 PMID:19680135 |
RGD:5129169, RGD:6903865, RGD:6903372 |
NCBI chr X:116,914,320...116,918,504
|
|
G |
Agtrap |
angiotensin II receptor-associated protein |
|
IEP |
protein:increased expression:kidney |
RGD |
PMID:18725581 |
RGD:2314351 |
NCBI chr 5:163,790,565...163,802,174
|
|
G |
Agxt2 |
alanine-glyoxylate aminotransferase 2 |
|
ISO |
DNA:SNP, haplotype:exon:multiple (human) |
RGD |
PMID:33879046 |
RGD:329961321 |
NCBI chr 2:61,063,416...61,104,828
|
|
G |
Ahcy |
adenosylhomocysteinase |
|
ISO |
associated with hyperhomocysteinemia |
RGD |
PMID:16815886 |
RGD:1601153 |
NCBI chr 3:164,029,338...164,044,562
|
|
G |
Ahr |
aryl hydrocarbon receptor |
treatment |
ISO IEP IMP |
CTD Direct Evidence: marker/mechanism associated with chronic intermittent hypoxia |
CTD RGD |
PMID:21115475 PMID:31489946 PMID:23528973 PMID:32416216 PMID:30127255 |
RGD:401793758, RGD:401793732, RGD:401793731, RGD:401793709 |
NCBI chr 6:57,961,423...57,998,901
|
|
G |
Ahrr |
aryl-hydrocarbon receptor repressor |
treatment |
IEP |
|
RGD |
PMID:30127255 PMID:31489946 |
RGD:401793709, RGD:401793758 |
NCBI chr 1:28,993,634...29,088,673
|
|
G |
Aif1 |
allograft inflammatory factor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:32147540 |
|
NCBI chr20:3,651,435...3,657,341
|
|
G |
Akt1 |
AKT serine/threonine kinase 1 |
|
IDA |
protein:increased serine phosphorylation:kidney |
RGD |
PMID:23323219 |
RGD:10041025 |
NCBI chr 6:137,534,810...137,555,131
|
|
G |
Akt2 |
AKT serine/threonine kinase 2 |
|
IEP |
mRNA:increased expression:cerebral cortex (rat) |
RGD |
PMID:12902546 |
RGD:2313350 |
NCBI chr 1:92,004,705...92,061,420
|
|
G |
Alad |
aminolevulinate dehydratase |
no_association |
ISO |
DNA:polymorphism CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:20123609 PMID:11335187 |
RGD:1601156 |
NCBI chr 5:75,961,993...75,972,334
|
|
G |
Alb |
albumin |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:2526952 |
|
NCBI chr14:17,891,564...17,907,043
|
|
G |
Aldh2 |
aldehyde dehydrogenase 2 family member |
susceptibility no_association |
ISO |
|
RGD |
PMID:11510748 PMID:12484509 |
RGD:1601164, RGD:1601163 |
NCBI chr12:40,610,244...40,643,220
|
|
G |
Alox12 |
arachidonate 12-lipoxygenase, 12S type |
|
IEP |
mRNA:decreased expression:medulla oblongata |
RGD |
PMID:16445702 |
RGD:5509789 |
NCBI chr10:54,958,263...54,970,542
|
|
G |
Alox15 |
arachidonate 15-lipoxygenase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22467300 |
|
NCBI chr10:55,559,060...55,567,535
|
|
G |
Alox5 |
arachidonate 5-lipoxygenase |
|
IDA |
|
RGD |
PMID:16331105 |
RGD:1626151 |
NCBI chr 4:151,203,948...151,251,126
|
|
G |
Angpt1 |
angiopoietin 1 |
|
ISO |
protein:increased expression:plasma, platelet |
RGD |
PMID:16942942 PMID:18285514 |
RGD:1626157, RGD:2316068 |
NCBI chr 7:75,415,959...75,668,696
|
|
G |
Anxa1 |
annexin A1 |
|
IEP ISO |
protein:altered localization:vascular associated smooth muscle cell CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:22228705 PMID:16109804 |
RGD:1599668 |
NCBI chr 1:227,287,713...227,306,739
|
|
G |
Aoc1 |
amine oxidase, copper containing 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:6218830 |
|
NCBI chr 4:79,143,126...79,162,705
|
|
G |
Aoc3 |
amine oxidase, copper containing 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23154672 |
|
NCBI chr10:86,272,757...86,280,702
|
|
G |
Apln |
apelin |
|
IEP |
mRNA:decreased expression:aorta, heart |
RGD |
PMID:15664402 |
RGD:1626176 |
NCBI chr X:132,058,739...132,091,518
|
|
G |
Apoa1 |
apolipoprotein A1 |
|
IEP ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:18224302 PMID:23401751 |
RGD:7241867 |
NCBI chr 8:55,423,945...55,425,729
|
|
G |
Apob |
apolipoprotein B |
|
ISO |
|
GAD |
PMID:15118671 |
RGD:1331525 |
NCBI chr 6:36,563,704...36,603,300
|
|
G |
Apoe |
apolipoprotein E |
onset |
ISO IEP |
CTD Direct Evidence: marker/mechanism mRNA:decreased expression:multiple (rat) |
CTD RGD |
PMID:20720404 PMID:22228705 PMID:15118671 PMID:20585107 |
RGD:1331525, RGD:6904214 |
NCBI chr 1:88,481,889...88,485,816
|
|
G |
App |
amyloid beta precursor protein |
|
IEP |
|
RGD |
PMID:29713228 |
RGD:13703136 |
NCBI chr11:37,506,207...37,724,351
|
|
G |
Aqp1 |
aquaporin 1 |
|
IEP ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:22228705 PMID:20156423 |
RGD:5148031 |
NCBI chr 4:85,812,784...85,824,964
|
|
G |
Aqp2 |
aquaporin 2 |
|
IEP |
protein:decreased expression:kidney medulla protein:increased expression:kidney medulla |
RGD |
PMID:16788141 PMID:16582573 |
RGD:1601242, RGD:1601243 |
NCBI chr 7:132,590,286...132,595,321
|
|
G |
Aqp4 |
aquaporin 4 |
|
IEP |
|
RGD |
PMID:20156423 |
RGD:5148031 |
NCBI chr18:6,782,389...6,799,034
|
|
G |
Ar |
androgen receptor |
treatment |
IDA ISO IMP |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:10523385 PMID:15746697 PMID:12397037 |
RGD:1601245, RGD:10043316 |
NCBI chr X:63,104,771...63,273,934
|
|
G |
Arg1 |
arginase 1 |
|
IMP IEP |
mRNA:increased expression:aorta (rat) |
RGD |
PMID:18475148 PMID:17223136 |
RGD:4142834, RGD:1626296 |
NCBI chr 1:22,295,093...22,307,720
|
|
G |
Arg2 |
arginase 2 |
|
IMP IEP |
mRNA:increased expression:lung mRNA:increased expression:aorta (rat) |
RGD |
PMID:18475148 PMID:20039818 PMID:17223136 |
RGD:4142834, RGD:4143278, RGD:1626296 |
NCBI chr 6:103,669,001...103,694,375
|
|
G |
Arhgdia |
Rho GDP dissociation inhibitor alpha |
|
IEP |
mRNA:decreased expression:urinary bladder protein:decreased expression:cortical collecting duct |
RGD |
PMID:19689474 PMID:25164814 |
RGD:9684972, RGD:9684979 |
NCBI chr10:106,352,858...106,356,347
|
|
G |
Arid1b |
AT-rich interaction domain 1B |
treatment |
IEP |
|
RGD |
PMID:17489020 |
RGD:9587762 |
NCBI chr 1:47,973,199...48,328,793
|
|
G |
Arnt |
aryl hydrocarbon receptor nuclear translocator |
treatment |
IEP |
|
RGD |
PMID:23528973 PMID:31489946 |
RGD:401793732, RGD:401793758 |
NCBI chr 2:182,997,731...183,056,584
|
|
G |
Arrb2 |
arrestin, beta 2 |
|
IEP |
protein:decreased expression:rostral ventrolateral medulla |
RGD |
PMID:27861247 |
RGD:13506896 |
NCBI chr10:55,645,539...55,653,485
|
|
G |
Atf2 |
activating transcription factor 2 |
|
IDA |
|
RGD |
PMID:11358932 |
RGD:10047414 |
NCBI chr 3:79,125,814...79,202,896
|
|
G |
Atg7 |
autophagy related 7 |
|
IEP |
protein:increased expression:skeletal muscle |
RGD |
PMID:24119246 |
RGD:11557985 |
NCBI chr 4:149,390,000...149,597,534
|
|
G |
Atox1 |
antioxidant 1 copper chaperone |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:22753205 |
|
NCBI chr10:39,564,855...39,579,892
|
|
G |
Atp1a1 |
ATPase Na+/K+ transporting subunit alpha 1 |
|
IAGP ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:23416519 PMID:8082931 |
RGD:1579862 |
NCBI chr 2:191,709,311...191,737,414
|
|
G |
Atp1a2 |
ATPase Na+/K+ transporting subunit alpha 2 |
susceptibility |
IEP ISO |
protein:decreased expression:adrenal gland cortex zone CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:16166162 PMID:16243970 PMID:11768735 PMID:11257061 PMID:16243970 |
RGD:1601253, RGD:1601254, RGD:1601251 |
NCBI chr13:84,729,597...84,754,544
|
|
G |
Atp2a3 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 |
|
IEP |
|
RGD |
PMID:11208768 |
RGD:68726 |
NCBI chr10:58,079,710...58,111,279
|
|
G |
Atp2b1 |
ATPase plasma membrane Ca2+ transporting 1 |
|
IEP ISO |
mRNA:increased expression:vascular associated smooth muscle cell CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:19430479 PMID:20137670 |
RGD:2317726 |
NCBI chr 7:35,622,267...35,731,904
|
|
G |
Atp2b3 |
ATPase plasma membrane Ca2+ transporting 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23416519 |
|
NCBI chr X:151,216,483...151,289,069
|
|
G |
Atp5f1a |
ATP synthase F1 subunit alpha |
|
IEP |
protein:decreased expression:heart left ventricle (rat) |
RGD |
PMID:24388463 |
RGD:7800726 |
NCBI chr18:73,567,537...73,575,473
|
|
G |
Atp6ap2 |
ATPase H+ transporting accessory protein 2 |
|
IEP |
|
RGD |
PMID:21321306 |
RGD:5132599 |
NCBI chr X:10,183,983...10,210,948
|
|
G |
Avp |
arginine vasopressin |
|
IEP ISO |
protein:increased expression:carotid artery CTD Direct Evidence: marker/mechanism protein:increased expression:plasma |
CTD RGD |
PMID:1663982 PMID:3346065 PMID:4040330 PMID:6367368 PMID:19133994 PMID:12623976 PMID:16582573 More...
|
RGD:1601305, RGD:1601243 |
NCBI chr 3:138,246,544...138,248,522
|
|
G |
Avpr1a |
arginine vasopressin receptor 1A |
|
IEP ISO |
mRNA, protein:increased expression:paraventricular hypothalamic nucleus mRNA, protein:increased expression:kidney, arteriole DNA:SNP |
RGD |
PMID:15475662 PMID:15657301 PMID:17653244 |
RGD:2300330, RGD:2300322, RGD:2300319 |
NCBI chr 7:59,999,743...60,003,667
|
|
G |
Avpr2 |
arginine vasopressin receptor 2 |
severity |
IDA |
|
RGD |
PMID:12072411 |
RGD:1298694 |
NCBI chr X:156,785,009...156,787,477
|
|
G |
B2m |
beta-2 microglobulin |
|
ISO |
protein:increased expression:serum |
RGD |
PMID:15957539 |
RGD:1601306 |
NCBI chr 3:129,549,236...129,555,354
|
|
G |
Bad |
BCL2-associated agonist of cell death |
treatment |
IEP |
|
RGD |
PMID:20065158 |
RGD:10053702 |
NCBI chr 1:213,562,719...213,572,034
|
|
G |
Bax |
BCL2 associated X, apoptosis regulator |
treatment |
IEP |
|
RGD |
PMID:20065158 |
RGD:10053702 |
NCBI chr 1:105,076,472...105,081,906
|
|
G |
Bche |
butyrylcholinesterase |
|
ISO |
|
RGD |
PMID:12387587 |
RGD:1601322 |
NCBI chr 2:160,607,289...160,699,760
|
|
G |
Bcl2 |
BCL2, apoptosis regulator |
treatment |
IEP ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:10075388 PMID:20065158 |
RGD:10053702 |
NCBI chr13:23,204,464...23,366,900
|
|
G |
Bdkrb1 |
bradykinin receptor B1 |
|
IMP IEP ISO |
|
RGD |
PMID:17988733 PMID:12025958 PMID:15643125 |
RGD:5129214, RGD:704378, RGD:1625732 |
NCBI chr 6:130,275,631...130,284,968
|
|
G |
Bdkrb2 |
bradykinin receptor B2 |
|
IEP ISO |
protein:increased expression:spinal cord CTD Direct Evidence: marker/mechanism mRNA:increased expression:hypothalamus DNA:SNP:promoter:-58T>C (human) |
CTD RGD |
PMID:10614985 PMID:11934804 PMID:15118671 PMID:12025958 PMID:10904024 |
RGD:4890455, RGD:1331525, RGD:704378, RGD:4891034 |
NCBI chr 6:130,237,055...130,267,205
|
|
G |
Becn1 |
beclin 1 |
|
IEP |
protein:increased expression:brain |
RGD |
PMID:23499735 |
RGD:11561939 |
NCBI chr10:86,731,649...86,747,002
|
|
G |
Bmal2 |
basic helix-loop-helix ARNT like 2 |
|
ISO |
DNA:SNPs: :rs6486121, rs3789327, rs969485(human) |
RGD |
PMID:17728404 |
RGD:2314371 |
NCBI chr 4:179,699,432...179,747,710
|
|
G |
Bmp2 |
bone morphogenetic protein 2 |
treatment |
IEP |
|
RGD |
PMID:33364953 |
RGD:329956421 |
NCBI chr 3:141,264,648...141,275,416
|
|
G |
Brca1 |
BRCA1, DNA repair associated |
treatment |
ISO |
|
RGD |
PMID:24239235 |
RGD:8693672 |
NCBI chr10:86,917,693...86,978,012
|
|
G |
Brs3 |
bombesin receptor subtype 3 |
|
ISO |
|
RGD |
PMID:9367152 |
RGD:734661 |
NCBI chr X:134,906,817...134,932,321
|
|
G |
C3 |
complement C3 |
|
IEP |
|
RGD |
PMID:22416803 |
RGD:11040890 |
NCBI chr 9:2,174,412...2,201,339
|
|
G |
Cacna1c |
calcium voltage-gated channel subunit alpha1 C |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22949532 |
|
NCBI chr 4:151,764,138...152,379,454
|
|
G |
Cacna2d1 |
calcium voltage-gated channel auxiliary subunit alpha2delta 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22949532 |
|
NCBI chr 4:19,902,324...20,330,287
|
|
G |
Cacnb2 |
calcium voltage-gated channel auxiliary subunit beta 2 |
susceptibility |
ISO |
DNA:SNP: :rs4373814(human) |
RGD |
PMID:24338417 |
RGD:13513987 |
NCBI chr17:82,473,097...82,818,564
|
|
G |
Calca |
calcitonin-related polypeptide alpha |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:1849535 PMID:9887042 |
|
NCBI chr 1:178,312,636...178,317,588
|
|
G |
Capn6 |
calpain 6 |
|
IEP |
associated with high salt diet; mRNA:decreased expression:heart (rat) |
RGD |
PMID:15665521 |
RGD:405101696 |
NCBI chr X:107,380,774...107,405,489
|
|
G |
Capn9 |
calpain 9 |
|
IEP |
associated with high salt diet; mRNA:decreased expression:heart (rat) |
RGD |
PMID:15665521 |
RGD:405101696 |
NCBI chr19:52,549,448...52,586,413
|
|
G |
Casp3 |
caspase 3 |
treatment |
IDA IEP |
|
RGD |
PMID:20065158 PMID:27929425 |
RGD:10053702, RGD:13782308 |
NCBI chr16:52,395,539...52,413,794
|
|
G |
Casp8 |
caspase 8 |
|
IEP |
|
RGD |
PMID:27929425 |
RGD:13782308 |
NCBI chr 9:67,747,109...67,806,699
|
|
G |
Casp9 |
caspase 9 |
|
IEP |
|
RGD |
PMID:27929425 |
RGD:13782308 |
|
|
G |
Cast |
calpastatin |
|
IEP |
associated with high salt diet; mRNA:increased expression:heart (rat) |
RGD |
PMID:15665521 |
RGD:405101696 |
NCBI chr 2:5,707,633...5,817,213
|
|
G |
Cat |
catalase |
|
IEP ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:11479740 PMID:20667508 PMID:21593737 PMID:22228705 PMID:16716903 |
RGD:1580833 |
NCBI chr 3:110,297,340...110,329,526
|
|
G |
Cav1 |
caveolin 1 |
|
IEP ISO |
protein:increased expression:artery smooth muscle, blood vessel endothelial cell CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:1798635 PMID:17986358 |
RGD:2289116 |
NCBI chr 4:46,606,538...46,639,616
|
|
G |
Cbs |
cystathionine beta synthase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18224302 |
|
NCBI chr20:9,708,089...9,732,623
|
|
G |
Ccl2 |
C-C motif chemokine ligand 2 |
ameliorates treatment |
IEP ISO IDA |
protein:increased expression:urine associated with Cardiac Fibrosis CTD Direct Evidence: marker/mechanism associated with Diabetes Mellitus, Non-Insulin-Dependent;mRNA, protein:increased expression:kidney cortex, urine |
CTD RGD |
PMID:20667508 PMID:27292124 PMID:17989143 PMID:25715999 PMID:17922026 PMID:18459944 More...
|
RGD:2307054, RGD:401794570, RGD:8549771, RGD:2307029 |
NCBI chr10:67,503,077...67,504,875
|
|
G |
Ccl28 |
C-C motif chemokine ligand 28 |
no_association |
IEP |
mRNA, protein:decreased expression:kidney (rat) protein:increased expression:kidney (rat) |
RGD |
PMID:19829664 PMID:16840655 |
RGD:4892132, RGD:2298761 |
NCBI chr 2:53,334,071...53,358,709
|
|
G |
Ccl5 |
C-C motif chemokine ligand 5 |
|
ISO |
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:serum |
RGD |
PMID:15668187 |
RGD:2307105 |
NCBI chr10:68,820,330...68,824,906
|
|
G |
Ccn2 |
cellular communication network factor 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16685210 |
|
NCBI chr 1:22,621,498...22,624,614
|
|
G |
Ccne1 |
cyclin E1 |
|
IEP |
protein:increased expression:vascular associated smooth muscle cell |
RGD |
PMID:12847112 |
RGD:2289296 |
NCBI chr 1:99,918,672...99,927,986
|
|
G |
Ccr5 |
C-C motif chemokine receptor 5 |
|
IEP ISO |
mRNA:increased expression:aorta (rat) DNA:frameshift mutation:cds:p.S185_T195del rs333 (human) |
RGD |
PMID:20044442 PMID:12680626 |
RGD:4890416, RGD:1581182 |
NCBI chr 8:132,629,097...132,660,980
|
|
G |
Cd14 |
CD14 molecule |
|
ISO |
associated with Glomerulonephritis, IGA; DNA:polymorphism: :-159C>T (human) |
RGD |
PMID:22072187 |
RGD:7204129 |
NCBI chr18:28,609,558...28,611,409
|
|
G |
Cd36 |
CD36 molecule |
|
IEP ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:18587397 PMID:18587397 |
RGD:2300254 |
NCBI chr 4:18,209,088...18,302,142
|
|
G |
Cd82 |
Cd82 molecule |
|
IEP |
mRNA:increased expression:thymus |
RGD |
PMID:10321446 |
RGD:2289422 |
NCBI chr 3:99,842,748...99,887,298
|
|
G |
Cdkn2a |
cyclin-dependent kinase inhibitor 2A |
|
IEP |
protein:increased expression:kidney |
RGD |
PMID:18504326 |
RGD:2316082 |
NCBI chr 5:109,100,763...109,114,448
|
|
G |
Cdo1 |
cysteine dioxygenase type 1 |
|
IEP |
protein:decreased expression:brain |
RGD |
PMID:6726227 |
RGD:2301363 |
NCBI chr18:39,432,473...39,447,253
|
|
G |
Cela2a |
chymotrypsin like elastase 2A |
|
ISO |
CTD Direct Evidence: marker/mechanism ClinVar Annotator: match by term: Hypertension |
CTD ClinVar |
PMID:21602471 PMID:25741868 PMID:31358993 |
|
NCBI chr 5:154,126,879...154,136,630
|
|
G |
Chga |
chromogranin A |
no_association |
ISO IEP |
protein:creased expression:adrenal gland mRNA, protein:increased expression:adrenal gland medulla, plasma DNA:polymorphisms:promoter |
RGD |
PMID:21061160 PMID:10803489 PMID:10803489 PMID:20113265 PMID:20729505 |
RGD:6906897, RGD:6907055, RGD:6907055, RGD:6906902, RGD:6906900 |
NCBI chr 6:121,696,051...121,707,399
|
|
G |
Chi3l1 |
chitinase 3 like 1 |
|
IEP |
mRNA:increased expression:brainstem, solitary tract nucleus (rat) |
RGD |
PMID:18703386 |
RGD:4892597 |
NCBI chr13:45,641,802...45,649,787
|
|
G |
Chst12 |
carbohydrate sulfotransferase 12 |
|
IEP |
mRNA:decreased expression:renal cortex and medulla (rat) |
RGD |
PMID:25001272 |
RGD:8693701 |
NCBI chr12:14,110,631...14,129,099
|
|
G |
Clcnka |
chloride voltage-gated channel Ka |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18480177 |
|
NCBI chr 5:153,691,208...153,706,295
|
|
G |
Clcnkb |
chloride voltage-gated channel Kb |
no_association |
ISO |
DNA:polymorphism:T481S |
RGD |
PMID:15148291 PMID:16003175 |
RGD:1600684, RGD:1600683 |
NCBI chr 5:153,710,086...153,733,162
|
|
G |
Cldn16 |
claudin 16 |
|
IDA |
Protein:decreased serine phosphorylation:kidney |
RGD |
PMID:16959063 |
RGD:1599616 |
NCBI chr11:74,290,298...74,309,588
|
|
G |
Clock |
clock circadian regulator |
|
IEP |
mRNA:altered expression:gastrocnemius muscle (rat) |
RGD |
PMID:22076133 |
RGD:9686076 |
NCBI chr14:32,262,747...32,346,872
|
|
G |
Clu |
clusterin |
|
ISO |
DNA:SNP:exon:866C>T (human) |
RGD |
PMID:15925890 |
RGD:1581195 |
NCBI chr15:40,161,068...40,200,315
|
|
G |
Cma1 |
chymase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:14620933 |
|
NCBI chr15:33,387,351...33,390,133
|
|
G |
Cnr1 |
cannabinoid receptor 1 |
|
IMP |
|
RGD |
PMID:19133994 |
RGD:2314680 |
NCBI chr 5:53,204,867...53,230,396
|
|
G |
Col1a1 |
collagen type I alpha 1 chain |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:11682445 |
|
NCBI chr10:80,380,458...80,397,461
|
|
G |
Col3a1 |
collagen type III alpha 1 chain |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:11682445 |
|
NCBI chr 9:54,866,646...54,902,578
|
|
G |
Col4a5 |
collagen type IV alpha 5 chain |
|
ISO |
ClinVar Annotator: match by term: Hypertension |
ClinVar |
PMID:9848783 PMID:11223851 PMID:12028435 PMID:14514738 PMID:17396119 PMID:19728970 PMID:19965530 PMID:20378821 PMID:21332469 PMID:21688191 PMID:24046192 PMID:24077912 PMID:24470729 PMID:25741868 PMID:26467025 PMID:26809805 PMID:26934356 PMID:28492532 PMID:28844315 PMID:29142990 PMID:29526710 PMID:29854973 PMID:30348286 PMID:30586318 PMID:30661074 PMID:30691124 PMID:31850286 PMID:32359821 PMID:33040356 PMID:33226606 PMID:33233744 PMID:33309955 PMID:33854215 PMID:34008892 PMID:35022790 PMID:35643372 More...
|
|
NCBI chr X:109,907,251...110,111,214
|
|
G |
Col6a3 |
collagen type VI alpha 3 chain |
|
ISO |
DNA:SNP:CDS:E1386K (rs146092501) (human) |
RGD |
PMID:30226566 |
RGD:401851058 |
NCBI chr 9:98,809,171...98,887,060
|
|
G |
Comt |
catechol-O-methyltransferase |
susceptibility |
IEP IDA ISO |
protein:increased expression:cerebral cortex DNA:polymorphism: :-1187G>C, 186C>T |
RGD |
PMID:17978496 PMID:17510509 PMID:17143180 PMID:14714585 |
RGD:2289729, RGD:8662344, RGD:2289742, RGD:2289787 |
NCBI chr11:96,072,371...96,091,956
|
|
G |
Corin |
corin, serine peptidase |
|
ISO |
|
RGD |
PMID:17485366 PMID:16216958 |
RGD:1626338, RGD:1581219 |
NCBI chr14:36,034,613...36,264,671
|
|
G |
Cox5b |
cytochrome c oxidase subunit 5B |
|
IEP |
protein:decreased expression:heart left ventricle |
RGD |
PMID:16132109 |
RGD:2301377 |
NCBI chr 9:38,921,980...38,923,806
|
|
G |
Cps1 |
carbamoyl-phosphate synthase 1 |
|
IEP |
protein:decreased expression:liver, mitochondrion |
RGD |
PMID:19135993 |
RGD:2303405 |
NCBI chr 9:76,063,863...76,186,739
|
|
G |
Creb1 |
cAMP responsive element binding protein 1 |
treatment |
IDA |
|
RGD |
PMID:21697807 |
RGD:10059385 |
NCBI chr 9:73,397,333...73,466,339
|
|
G |
Crhr1 |
corticotropin releasing hormone receptor 1 |
|
IDA |
corticotropin releasing hormone-induced |
RGD |
PMID:11036160 |
RGD:1581302 |
NCBI chr10:89,540,192...89,583,466
|
|
G |
Crhr2 |
corticotropin releasing hormone receptor 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:10742107 |
|
NCBI chr 4:85,553,163...85,596,203
|
|
G |
Crp |
C-reactive protein |
|
IEP ISO |
protein:increased expression:plasma CTD Direct Evidence: marker/mechanism protein:increased expression:serum: |
CTD RGD |
PMID:14620923 PMID:16680063 PMID:19770776 PMID:20667508 PMID:19905982 PMID:19056836 PMID:6720266 More...
|
RGD:5131461, RGD:9586008, RGD:9491754 |
NCBI chr13:87,694,062...87,695,978
|
|
G |
Ctf1 |
cardiotrophin 1 |
|
ISO IEP |
protein:increased expression:plasma mRNA:increased expression:cardiac ventricle |
RGD |
PMID:15716706 PMID:8604995 |
RGD:1626411, RGD:69823 |
NCBI chr 1:182,328,035...182,336,346
|
|
G |
Ctsc |
cathepsin C |
|
IEP |
|
RGD |
PMID:657443 |
RGD:1599651 |
NCBI chr 1:142,028,386...142,059,841
|
|
G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22352330 |
|
NCBI chr14:17,465,210...17,467,255
|
|
G |
Cxcr2 |
C-X-C motif chemokine receptor 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27678262 |
|
NCBI chr 9:75,729,493...75,735,868
|
|
G |
Cyba |
cytochrome b-245 alpha chain |
|
IDA ISO IEP |
CTD Direct Evidence: marker/mechanism protein:increased expression:kidney cortex |
CTD RGD |
PMID:16685210 PMID:17324946 PMID:20505675 PMID:32147540 PMID:17109653 PMID:12729892 PMID:20018820 More...
|
RGD:4775206, RGD:1580276, RGD:2317853 |
NCBI chr19:50,487,598...50,495,669
|
|
G |
Cybb |
cytochrome b-245 beta chain |
|
IEP ISO |
Protein:increased expression:brain CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:16685210 PMID:21593737 PMID:27659729 PMID:27847271 PMID:32147540 PMID:32165127 PMID:12472782 More...
|
RGD:1599685 |
NCBI chr X:16,030,596...16,065,065
|
|
G |
Cyp11a1 |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
|
IEP |
mRNA:increased expression:hypothalamus |
RGD |
PMID:16116051 |
RGD:1599701 |
NCBI chr 8:67,318,665...67,330,196
|
|
G |
Cyp11b1 |
cytochrome P450, family 11, subfamily b, polypeptide 1 |
|
IEP IAGP |
mRNA:decreased expression:hypothalamus, cerebellum, cortex (rat) |
RGD |
PMID:19837774 PMID:7981756 |
RGD:4891156, RGD:69709 |
NCBI chr 7:106,772,597...106,780,536
|
|
G |
Cyp11b2 |
cytochrome P450, family 11, subfamily b, polypeptide 2 |
|
ISO IMP IEP |
DNA:transition:5' utr:-344C>T (human) mRNA:increased expression:brainstem, hippocampus, cortex (rat) |
RGD |
PMID:10024332 PMID:18495825 PMID:19837774 |
RGD:4891152, RGD:2307304, RGD:4891156 |
NCBI chr 7:108,719,349...108,726,024
|
|
G |
Cyp11b3 |
cytochrome P450, family 11, subfamily b, polypeptide 3 |
|
ISO |
ClinVar Annotator: match by term: Aldosterone to renin ratio, increased |
ClinVar |
PMID:12213905 PMID:12788845 PMID:17003099 |
|
NCBI chr 7:106,808,559...106,814,048
|
|
G |
Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
|
IEP |
mRNA:decreased expression:ovary (rat) |
RGD |
PMID:19228890 |
RGD:4761326 |
NCBI chr 8:63,449,148...63,476,534
|
|
G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
treatment |
ISO IEP |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:20634294 PMID:22995157 PMID:20634294 PMID:31489946 PMID:23528973 PMID:30127255 More...
|
RGD:7257731, RGD:401793758, RGD:401793732, RGD:401793709 |
NCBI chr 8:66,991,940...66,998,014
|
|
G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
treatment |
IEP |
|
RGD |
PMID:23528973 |
RGD:401793732 |
NCBI chr 6:21,093,927...21,103,091
|
|
G |
Cyp2c11 |
cytochrome P450, subfamily 2, polypeptide 11 |
|
ISO IEP |
|
RGD |
PMID:19669737 PMID:18829737 |
RGD:6903909, RGD:6903915 |
NCBI chr 1:246,175,216...246,211,445
|
|
G |
Cyp2j4 |
cytochrome P450, family 2, subfamily j, polypeptide 4 |
susceptibility |
ISO |
DNA:SNP |
RGD |
PMID:17286575 PMID:20501636 |
RGD:1625379, RGD:7243136 |
NCBI chr 5:116,295,691...116,323,219
|
|
G |
Cyp2r1 |
cytochrome P450, family 2, subfamily r, polypeptide 1 |
|
ISO |
DNA:SNP:CDS: rs12794714 (human) DNA:SNP:CDS:rs12794714 (human) DNA:SNP:CDS:rs10741657|rs12794714 (human) DNA:SNP:CDS:rs1993116|rs10741657 (human) |
RGD |
PMID:34906413 PMID:24974252 PMID:28760944 PMID:30192652 |
RGD:401900724, RGD:401901148, RGD:401901082, RGD:401901076 |
NCBI chr 1:168,749,302...168,798,079
|
|
G |
Cyp4a1 |
cytochrome P450, family 4, subfamily a, polypeptide 1 |
|
ISO IEP |
mRNA:decreased expression:kidney cortex |
RGD |
PMID:16144986 PMID:16339392 PMID:18952718 |
RGD:1625567, RGD:2303383, RGD:2303381 |
NCBI chr 5:129,123,323...129,137,464
|
|
G |
Cyp4a8 |
cytochrome P450, family 4, subfamily a, polypeptide 8 |
|
IEP |
mRNA:decreased expression:kidney cortex |
RGD |
PMID:18952718 PMID:16339392 |
RGD:2303381, RGD:2303383 |
NCBI chr 5:128,702,130...128,733,476
|
|
G |
Cyp4f1 |
cytochrome P450, family 4, subfamily f, polypeptide 1 |
|
IEP |
mRNA:increased expression:kidney |
RGD |
PMID:16182239 |
RGD:2301709 |
NCBI chr 7:12,010,850...12,022,497
|
|
G |
Dars2 |
aspartyl-tRNA synthetase 2 (mitochondrial) |
|
ISO |
ClinVar Annotator: match by term: Hypertension |
ClinVar |
PMID:16199547 PMID:17384640 PMID:19592391 PMID:22843165 PMID:23065766 PMID:23652419 PMID:24005482 PMID:24407472 PMID:24566671 PMID:25525159 PMID:25741868 PMID:28492532 PMID:31589614 PMID:33977142 PMID:34426522 PMID:35379322 More...
|
|
NCBI chr13:73,308,726...73,336,558
|
|
G |
Dbh |
dopamine beta-hydroxylase |
resistance |
IEP ISO |
mRNA:increased expression:heart, adrenal gland (rat) DNA:polymorphism:5' utr:g.-2073C>T rs1989787 (human) |
RGD |
PMID:20596792 PMID:20814407 |
RGD:5129234, RGD:5129211 |
NCBI chr 3:30,886,313...30,903,313
|
|
G |
Ddah1 |
dimethylarginine dimethylaminohydrolase 1 |
susceptibility |
ISO |
|
RGD |
PMID:16444868 |
RGD:1625582 |
NCBI chr 2:234,667,499...234,800,322
|
|
G |
Dio2 |
iodothyronine deiodinase 2 |
susceptibility |
ISO |
|
RGD |
PMID:17224473 |
RGD:1626437 |
NCBI chr 6:115,396,308...115,410,594
|
|
G |
Drd1 |
dopamine receptor D1 |
|
ISO |
|
RGD |
PMID:10948075 PMID:8636408 |
RGD:1580869, RGD:1300303 |
NCBI chr17:10,545,488...10,550,029
|
|
G |
Drd2 |
dopamine receptor D2 |
|
ISO |
DNA:polymorphism CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:11566895 PMID:15939106 PMID:11494094 |
RGD:1600905, RGD:1580874 |
NCBI chr 8:58,605,403...58,669,339
|
|
G |
Drd3 |
dopamine receptor D3 |
|
IDA |
|
RGD |
PMID:11675403 |
RGD:1580882 |
NCBI chr11:70,385,586...70,437,793
|
|
G |
Drd5 |
dopamine receptor D5 |
|
ISO |
|
RGD |
PMID:12486173 |
RGD:1580887 |
NCBI chr14:72,487,950...72,491,050
|
|
G |
Dusp1 |
dual specificity phosphatase 1 |
|
IEP |
mRNA, protein:increased expression:aorta |
RGD |
PMID:9231829 |
RGD:2298678 |
NCBI chr10:17,184,853...17,187,646
|
|
G |
Dusp5 |
dual specificity phosphatase 5 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:25397684 |
|
NCBI chr 1:262,543,774...262,557,201
|
|
G |
Dynll1 |
dynein light chain LC8-type 1 |
treatment |
IMP |
|
RGD |
PMID:24035314 |
RGD:13207430 |
NCBI chr12:46,945,291...46,976,867
|
|
G |
Ece1 |
endothelin converting enzyme 1 |
|
IDA ISO IEP |
CTD Direct Evidence: marker/mechanism mRNA,protein:increased expression,increased activity:kidney medulla |
CTD RGD |
PMID:12566389 PMID:12193123 PMID:10894793 |
RGD:1580907, RGD:7244182 |
NCBI chr 5:155,361,031...155,462,723
|
|
G |
Edn1 |
endothelin 1 |
|
IEP ISO |
protein:increased secretion:plasma (rat) CTD Direct Evidence: marker/mechanism human gene in a rat model associated with Diabetic Nephropathies;protein:increased secretion:plasma DNA:polymorphism:exon:p.K198N (human) |
CTD RGD |
PMID:7721406 PMID:8152482 PMID:8440307 PMID:10474778 PMID:10669576 PMID:11847185 PMID:12149661 PMID:12425201 PMID:12600921 PMID:15188945 PMID:15302986 PMID:15314687 PMID:15834289 PMID:17130675 PMID:20733093 PMID:11078355 PMID:18496905 PMID:17444275 More...
|
RGD:4144829, RGD:8661804, RGD:2313283, RGD:1625065 |
NCBI chr17:22,660,799...22,666,687
|
|
G |
Edn2 |
endothelin 2 |
|
ISO |
mRNA:increased expression:leukocyte |
RGD |
PMID:10976780 PMID:10489105 PMID:15007037 |
RGD:1580916, RGD:1580917, RGD:1625402 |
NCBI chr 5:133,751,316...133,756,814
|
|
G |
Edn3 |
endothelin 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:2059916 |
|
NCBI chr 3:163,562,307...163,586,636
|
|
G |
Ednra |
endothelin receptor type A |
|
IEP ISO IDA |
associated with Uremia CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:12600921 PMID:20144075 PMID:14616768 PMID:16157796 |
RGD:4892284, RGD:1580950, RGD:1581830 |
NCBI chr19:47,137,360...47,207,961
|
|
G |
Ednrb |
endothelin receptor type B |
|
IEP IMP |
associated with Uremia |
RGD |
PMID:20144075 PMID:10749572 |
RGD:4892284, RGD:628518 |
NCBI chr15:87,055,490...87,086,765
|
|
G |
Egfr |
epidermal growth factor receptor |
|
IEP |
mRNA, protein:increased expression:renal cortex |
RGD |
PMID:15827348 |
RGD:1580953 |
NCBI chr14:95,378,626...95,551,358
|
|
G |
Egln1 |
egl-9 family hypoxia-inducible factor 1 |
|
IMP |
|
RGD |
PMID:22686466 |
RGD:11252087 |
NCBI chr19:52,867,900...52,907,308
|
|
G |
Eif4g2 |
eukaryotic translation initiation factor 4, gamma 2 |
|
IEP |
mRNA:increased expression:heart left ventricle |
RGD |
PMID:12708758 |
RGD:10755511 |
NCBI chr 1:165,181,433...165,193,583
|
|
G |
Eln |
elastin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17039479 |
|
NCBI chr12:27,604,983...27,648,413
|
|
G |
Emilin1 |
elastin microfibril interfacer 1 |
|
ISO |
|
RGD |
PMID:16530041 |
RGD:1580958 |
NCBI chr 6:25,455,974...25,463,713
|
|
G |
Eng |
endoglin |
|
IEP |
mRNA:decreased expression:kidney (rat) |
RGD |
PMID:19829664 |
RGD:4892132 |
NCBI chr 3:36,332,190...36,370,324
|
|
G |
Eno1 |
enolase 1 |
|
IEP |
|
RGD |
PMID:16485256 |
RGD:1598909 |
NCBI chr 5:160,719,951...160,731,337
|
|
G |
Eno2 |
enolase 2 |
severity |
ISO |
protein:increased expression:serum |
RGD |
PMID:21130083 |
RGD:5508770 |
NCBI chr 4:159,258,371...159,267,220
|
|
G |
Entpd2 |
ectonucleoside triphosphate diphosphohydrolase 2 |
|
IEP |
|
RGD |
PMID:20655932 |
RGD:9685529 |
NCBI chr 3:28,611,722...28,617,237
|
|
G |
Ep300 |
E1A binding protein p300 |
|
IEP |
protein:increased expression:left ventricle (rat) |
RGD |
PMID:18292809 |
RGD:2312265 |
NCBI chr 7:114,987,857...115,058,652
|
|
G |
Ephx2 |
epoxide hydrolase 2 |
susceptibility |
IDA IMP ISO |
DNA:missense mutation:cds:p.K55R (human) |
RGD |
PMID:16157792 PMID:21720266 PMID:19553349 PMID:20065888 |
RGD:1580985, RGD:5688733, RGD:5688730, RGD:5688727 |
NCBI chr15:40,289,901...40,327,632
|
|
G |
Epo |
erythropoietin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:1516988 PMID:10694834 |
|
NCBI chr12:19,204,258...19,207,948
|
|
G |
Epor |
erythropoietin receptor |
susceptibility |
ISO |
induced by erythropoietin; |
RGD |
PMID:19458615 |
RGD:11041646 |
NCBI chr 8:28,765,738...28,770,371
|
|
G |
Erap1 |
endoplasmic reticulum aminopeptidase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:13678427 |
|
NCBI chr 2:5,666,337...5,705,256
|
|
G |
Esr2 |
estrogen receptor 2 |
|
ISO IMP |
|
RGD |
PMID:11799247 PMID:23608653 PMID:11185739 PMID:15167447 |
RGD:734949, RGD:7364951, RGD:1581015, RGD:1581017 |
NCBI chr 6:100,589,553...100,645,240
|
|
G |
F11 |
coagulation factor XI |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:6383834 |
|
NCBI chr16:46,987,988...47,009,015
|
|
G |
F11r |
F11 receptor |
susceptibility |
ISO IEP |
DNA:SNPs: :rs790056, rs2774276 (human) |
RGD |
PMID:18067551 PMID:17420334 |
RGD:7488938, RGD:7488939 |
NCBI chr13:86,406,229...86,429,819
|
|
G |
F12 |
coagulation factor XII |
|
ISO |
CTD Direct Evidence: marker/mechanism ClinVar Annotator: match by term: Hypertension |
CTD ClinVar |
PMID:6383834 PMID:16638441 PMID:25741868 |
|
NCBI chr17:9,212,819...9,220,664
|
|
G |
F2r |
coagulation factor II (thrombin) receptor |
|
IDA |
|
RGD |
PMID:9168786 |
RGD:1581034 |
NCBI chr 2:26,869,343...26,885,856
|
|
G |
F3 |
coagulation factor III, tissue factor |
treatment |
IEP |
|
RGD |
PMID:21423288 |
RGD:11341709 |
NCBI chr 2:212,511,675...212,523,375
|
|
G |
F7 |
coagulation factor VII |
|
ISO IEP |
protein:increased activity:plasma (human) protein:increased activity:plasma (rat) |
RGD |
PMID:10450539 PMID:8123879 PMID:812575 |
RGD:2312402, RGD:2312412, RGD:2312323 |
NCBI chr16:83,191,896...83,202,775
|
|
G |
Fabp1 |
fatty acid binding protein 1 |
|
ISO |
possibly associated with arteriosclerosis (MeSH:D001161) |
RGD |
PMID:15830271 |
RGD:1626441 |
NCBI chr 4:104,744,302...104,753,119
|
|
G |
Fabp3 |
fatty acid binding protein 3 |
susceptibility |
ISO |
DNA:SNPs |
RGD |
PMID:18437121 |
RGD:2307331 |
NCBI chr 5:142,651,962...142,658,707
|
|
G |
Fadd |
Fas associated via death domain |
treatment |
IEP |
|
RGD |
PMID:24355328 |
RGD:11344883 |
NCBI chr 1:209,169,245...209,175,423
|
|
G |
Fads1 |
fatty acid desaturase 1 |
|
IEP |
|
RGD |
PMID:12144877 |
RGD:1625415 |
NCBI chr 1:216,252,605...216,267,618
|
|
G |
Fah |
fumarylacetoacetate hydrolase |
|
IEP |
mRNA:decreased expression:kidney |
RGD |
PMID:15731461 |
RGD:1559295 |
NCBI chr 1:138,548,830...138,571,599
|
|
G |
Fbn1 |
fibrillin 1 |
|
IEP |
protein:increased expression:renal glomerulus (rat) |
RGD |
PMID:16380460 |
RGD:7365080 |
NCBI chr 3:112,554,257...112,750,835
|
|
G |
Fgf2 |
fibroblast growth factor 2 |
|
IEP |
associated with Aortic Coarctation |
RGD |
PMID:17562191 |
RGD:8655614 |
NCBI chr 2:122,164,454...122,218,796
|
|
G |
Fgf21 |
fibroblast growth factor 21 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:29706566 |
|
NCBI chr 1:105,219,825...105,221,376
|
|
G |
Fmo3 |
flavin containing dimethylaniline monoxygenase 3 |
no_association |
ISO |
associated with trimethylaminuria, OMIM:602079 |
RGD |
PMID:9536088 PMID:16324215 |
RGD:1626461, RGD:1626466 |
NCBI chr13:75,309,367...75,334,915
|
|
G |
Fn1 |
fibronectin 1 |
|
ISO IEP IAGP |
CTD Direct Evidence: marker/mechanism mRNA:increased expression:kidney (SHRSP/A3N rat) |
CTD RGD |
PMID:11682445 PMID:17324946 PMID:11907153 PMID:11682445 |
RGD:28912746, RGD:30296650 |
NCBI chr 9:80,645,507...80,714,200
|
|
G |
Fndc5 |
fibronectin type III domain containing 5 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:32165127 |
|
NCBI chr 5:141,481,593...141,491,257
|
|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
|
IEP ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:12044476 PMID:24039778 PMID:16696897 |
RGD:7242185 |
NCBI chr 6:110,852,188...110,855,054
|
|
G |
Foxp3 |
forkhead box P3 |
treatment |
IEP |
|
RGD |
PMID:24420551 |
RGD:38549366 |
NCBI chr X:17,580,380...17,601,181
|
|
G |
Fto |
FTO, alpha-ketoglutarate dependent dioxygenase |
|
ISO |
associated with Obesity DNA:SNP:intron:rs9302652 (human) |
RGD |
PMID:31801409 PMID:20031594 |
RGD:329812016, RGD:329901765 |
NCBI chr19:31,456,749...31,865,011
|
|
G |
Fxyd2 |
FXYD domain-containing ion transport regulator 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22228705 |
|
NCBI chr 8:45,712,901...45,720,032
|
|
G |
Gabbr1 |
gamma-aminobutyric acid type B receptor subunit 1 |
|
IEP |
mRNA:increased expression:brain |
RGD |
PMID:18338268 |
RGD:2315462 |
NCBI chr20:1,469,779...1,499,352
|
|
G |
Gad1 |
glutamate decarboxylase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:32165127 |
|
NCBI chr 3:75,777,260...75,818,099
|
|
G |
Gal |
galanin and GMAP prepropeptide |
|
IEP ISO |
mRNA:decreased expression:paraventricular hypothalamic nucleus, solitary tract nucleus CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:10818254 PMID:15275958 |
RGD:1624333 |
NCBI chr 1:210,079,709...210,084,572
|
|
G |
Gata5 |
GATA binding protein 5 |
susceptibility |
ISO |
DNA:SNPs:intron, exon:rs6061245,rs6587239 (human) |
RGD |
PMID:26617239 |
RGD:11343485 |
NCBI chr 3:187,796,140...187,804,327
|
|
G |
Gcg |
glucagon |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22228705 |
|
NCBI chr 3:67,522,489...67,531,533
|
|
G |
Gch1 |
GTP cyclohydrolase 1 |
treatment sexual_dimorphism |
ISO IDA IMP IEP |
CTD Direct Evidence: marker/mechanism mRNA:decreased expression:aorta DNA:SNV:3' UTR: 59038C>T (rs841, +243C>T) (human) |
CTD RGD |
PMID:12855421 PMID:12925450 PMID:33857222 PMID:15167268 PMID:12623977 PMID:17717598 More...
|
RGD:401700397, RGD:401700394, RGD:329970288, RGD:329961330, RGD:329961329 |
NCBI chr15:20,404,267...20,437,727
|
|
G |
Gck |
glucokinase |
susceptibility |
ISO |
|
RGD |
PMID:9324112 |
RGD:1581877 |
NCBI chr14:84,999,019...85,041,098
|
|
G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22228705 |
|
NCBI chr 8:87,510,251...87,548,896
|
|
G |
Ghsr |
growth hormone secretagogue receptor |
|
ISO |
associated with Obesity |
RGD |
PMID:24760503 |
RGD:12910115 |
NCBI chr 2:110,268,489...110,271,865
|
|
G |
Gja1 |
gap junction protein, alpha 1 |
treatment |
IEP ISO |
CTD Direct Evidence: marker/mechanism|therapeutic |
CTD RGD |
PMID:16448880 PMID:36720419 PMID:16448880 PMID:23719203 |
RGD:7207810, RGD:8662439 |
NCBI chr20:36,302,490...36,315,010
|
|
G |
Gja4 |
gap junction protein, alpha 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16448880 |
|
NCBI chr 5:139,633,324...139,635,857
|
|
G |
Gja5 |
gap junction protein, alpha 5 |
treatment |
IDA ISO IEP |
CTD Direct Evidence: marker/mechanism protein:decreased expression:artery endothelium |
CTD RGD |
PMID:19109587 PMID:19686729 PMID:11821709 |
RGD:7207417, RGD:7207848 |
NCBI chr 2:187,291,227...187,310,770
|
|
G |
Gjc1 |
gap junction protein, gamma 1 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:19109587 |
|
NCBI chr10:88,262,840...88,285,646
|
|
G |
Glce |
glucuronic acid epimerase |
|
ISO |
DNA:SNP: : rs3865014 (human) |
RGD |
PMID:27699767 |
RGD:401717571 |
NCBI chr 8:62,546,104...62,612,144
|
|
G |
Glp1r |
glucagon-like peptide 1 receptor |
|
IDA ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:22228705 PMID:12093887 |
RGD:625448 |
NCBI chr20:8,972,004...9,010,241
|
|
G |
Gnai2 |
G protein subunit alpha i2 |
treatment |
IMP IEP |
|
RGD |
PMID:27912212 PMID:15106810 |
RGD:13507308, RGD:13508592 |
NCBI chr 8:117,167,045...117,187,652
|
|
G |
Gnai3 |
G protein subunit alpha i3 |
treatment |
IEP |
|
RGD |
PMID:15106810 |
RGD:13508592 |
NCBI chr 2:198,430,920...198,468,874
|
|
G |
Gnas |
GNAS complex locus |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:9506701 PMID:12215464 PMID:15118671 |
RGD:1580404, RGD:1331525 |
NCBI chr 3:183,489,648...183,554,570
|
|
G |
Gnb3 |
G protein subunit beta 3 |
susceptibility no_association |
ISO |
DNA:SNP:cds:825C>T (human) CTD Direct Evidence: marker/mechanism DNA:SNP:cds: 825C>T (human) DNA:polymorphism: :multiple (human) |
CTD RGD |
PMID:15961981 PMID:16141801 PMID:10526907 PMID:11230982 PMID:16908025 |
RGD:1580410, RGD:1580408, RGD:2313206 |
NCBI chr 4:157,639,468...157,645,171
|
|
G |
Gnrh1 |
gonadotropin releasing hormone 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:6350720 |
|
NCBI chr15:41,972,482...41,976,690
|
|
G |
Gp1ba |
glycoprotein Ib platelet subunit alpha |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22352330 |
|
NCBI chr10:55,352,938...55,355,804
|
|
G |
Gpx1 |
glutathione peroxidase 1 |
treatment |
ISO IEP IDA |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:21593737 PMID:17198913 PMID:31572179 PMID:21210316 PMID:23752977 |
RGD:1600704, RGD:329956417, RGD:11353777, RGD:11352825 |
NCBI chr 8:117,905,462...117,906,588
|
|
G |
Gpx3 |
glutathione peroxidase 3 |
treatment susceptibility |
IEP ISO |
DNA:SNP: : rs3828599 (human) DNA:SNP: :rs3828599 (human) |
RGD |
PMID:23528973 PMID:21933611 PMID:32034489 |
RGD:401793732, RGD:401827166, RGD:401827127 |
NCBI chr10:39,529,335...39,537,406
|
|
G |
Grk2 |
G protein-coupled receptor kinase 2 |
treatment |
IEP ISO |
protein:increased expression:lymphocyte, vascular associated smooth muscle cell CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:11901213 PMID:10642272 PMID:23913704 |
RGD:1625788, RGD:13792716 |
NCBI chr 1:211,010,259...211,031,013
|
|
G |
Grk3 |
G protein-coupled receptor kinase 3 |
|
IEP |
mRNA:increased expression:heart left ventricle, kidney (rat) |
RGD |
PMID:26248277 |
RGD:11535540 |
NCBI chr12:49,285,228...49,395,803
|
|
G |
Grk5 |
G protein-coupled receptor kinase 5 |
|
IEP |
mRNA:increased expression:heart left ventricle, kidney (rat) |
RGD |
PMID:26248277 |
RGD:11535540 |
NCBI chr 1:270,014,314...270,208,294
|
|
G |
Gsk3b |
glycogen synthase kinase 3 beta |
treatment |
IEP ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:22982863 PMID:22982863 |
RGD:10045670 |
NCBI chr11:76,004,502...76,154,665
|
|
G |
Gsr |
glutathione-disulfide reductase |
treatment |
ISO IEP |
|
RGD |
PMID:17198913 PMID:23528973 |
RGD:1600704, RGD:401793732 |
NCBI chr16:65,185,574...65,228,742
|
|
G |
Gsta5 |
glutathione S-transferase alpha 5 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22228705 |
|
NCBI chr 8:79,105,561...79,117,472
|
|
G |
Gstm1 |
glutathione S-transferase mu 1 |
|
IEP |
mRNA:decreased expression:kidney (rat) |
RGD |
PMID:15699453 |
RGD:7495838 |
NCBI chr 2:198,338,005...198,346,007
|
|
G |
Gstm2 |
glutathione S-transferase mu 2 |
treatment |
IEP |
mRNA:decreased expression:kidney (rat) |
RGD |
PMID:18008142 PMID:23528973 PMID:12624007 |
RGD:2302178, RGD:401793732, RGD:631154 |
NCBI chr 2:195,624,015...195,628,774
|
|
G |
Gstm3 |
glutathione S-transferase mu 3 |
treatment |
IEP |
|
RGD |
PMID:23528973 |
RGD:401793732 |
NCBI chr 2:195,590,450...195,612,578
|
|
G |
Gstp1 |
glutathione S-transferase pi 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:24915237 |
|
NCBI chr 1:210,767,237...210,770,242
|
|
G |
Gstt1 |
glutathione S-transferase theta 1 |
|
ISO |
associated with scleroderma, systemic;DNA:deletion: : CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:22228705 PMID:11477481 PMID:32034489 |
RGD:5490587, RGD:401827127 |
NCBI chr20:12,856,068...12,873,020
|
|
G |
Gstt2 |
glutathione S-transferase theta 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22228705 |
|
NCBI chr20:12,819,053...12,822,724
|
|
G |
Gucy1a1 |
guanylate cyclase 1 soluble subunit alpha 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18339647 |
|
NCBI chr 2:167,418,615...167,482,293
|
|
G |
H2ax |
H2A.X variant histone |
treatment |
IDA |
|
RGD |
PMID:24239235 |
RGD:8693672 |
NCBI chr 8:53,568,718...53,570,072
|
|
G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
|
IEP |
protein:increased expression:urine |
RGD |
PMID:23085980 |
RGD:7245484 |
NCBI chr10:31,118,667...31,151,730
|
|
G |
Hdac6 |
histone deacetylase 6 |
|
IEP |
protein:increased expression, activity:heart: |
RGD |
PMID:23868068 |
RGD:9681716 |
NCBI chr X:14,550,645...14,572,445
|
|
G |
Hdac8 |
histone deacetylase 8 |
|
IEP |
protein:decreased expression:heart (mouse, rat) |
RGD |
PMID:28567090 |
RGD:13208602 |
NCBI chr X:67,385,288...67,593,014
|
|
G |
Hgf |
hepatocyte growth factor |
susceptibility |
ISO |
DNA:polymorphism:intron13:C/A |
RGD |
PMID:15127882 PMID:15127882 |
RGD:1642064, RGD:1642064 |
NCBI chr 4:19,628,902...19,700,467
|
|
G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
|
ISO IEP |
Hypertension, Pregnancy-Induced;mRNA, protein:increased expression:placenta CTD Direct Evidence: therapeutic associated with Hypercholesterolemia;protein:increased expression:aorta protein:increased expression:brain |
CTD RGD |
PMID:22349312 PMID:15862159 PMID:11882589 PMID:16955051 |
RGD:1626322, RGD:1626330, RGD:1626317 |
NCBI chr 6:98,357,788...98,405,068
|
|
G |
Hk2 |
hexokinase 2 |
treatment |
IEP |
|
RGD |
PMID:31572179 |
RGD:329956417 |
NCBI chr 4:116,792,258...116,841,275
|
|
G |
Hmgb1 |
high mobility group box 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:32147540 |
|
NCBI chr12:11,009,236...11,015,941
|
|
G |
Hmox1 |
heme oxygenase 1 |
susceptibility treatment |
ISO IDA |
CTD Direct Evidence: marker/mechanism|therapeutic |
CTD RGD |
PMID:16959961 PMID:22349312 PMID:22352330 PMID:12872043 PMID:20836698 PMID:12215473 More...
|
RGD:1598400, RGD:10755717, RGD:1580453 |
NCBI chr19:13,452,365...13,479,823
|
|
G |
Hp |
haptoglobin |
susceptibility onset |
ISO IEP |
DNA:polymorphism CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:16597321 PMID:7606649 PMID:23401751 PMID:8228210 |
RGD:1626351, RGD:7241867, RGD:1626352 |
NCBI chr19:54,449,151...54,453,701
|
|
G |
Hrh2 |
histamine receptor H 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30310171 |
|
NCBI chr17:10,366,004...10,407,791
|
|
G |
Hrh3 |
histamine receptor H3 |
|
IDA ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:9050021 PMID:9050021 |
RGD:1626409 |
NCBI chr 3:167,191,551...167,196,642
|
|
G |
Hsd11b1 |
hydroxysteroid 11-beta dehydrogenase 1 |
susceptibility |
ISO |
CTD Direct Evidence: marker/mechanism DNA:SNP:5'utr: (rs846910) (human) |
CTD RGD |
PMID:9683905 PMID:15199296 PMID:21786805 PMID:15452033 |
RGD:329902060 |
NCBI chr13:104,728,539...104,798,884
|
|
G |
Hsd11b2 |
hydroxysteroid 11-beta dehydrogenase 2 |
|
IEP IMP ISO |
associated with Diabetes Mellitus, Experimental;mRNA:decreased expression:kidney CTD Direct Evidence: marker/mechanism apparent mineralocorticoid excess syndrome, OMIM:218030 |
CTD RGD |
PMID:7670488 PMID:9683905 PMID:9707624 PMID:11082157 PMID:10792625 PMID:26077568 PMID:9683587 More...
|
RGD:2308925, RGD:13800514, RGD:1625078 |
NCBI chr19:50,307,569...50,312,812
|
|
G |
Hsd11b2em1Jmul |
hydroxysteroid 11-beta dehydrogenase 2; ZFN induced mutant1, Jmul |
|
IMP |
|
RGD |
PMID:26077568 |
RGD:13800514 |
|
|
G |
Hsd17b4 |
hydroxysteroid (17-beta) dehydrogenase 4 |
|
IEP |
mRNA:decreased expression:renal cortex (rat) |
RGD |
PMID:18430809 |
RGD:2292646 |
NCBI chr18:45,515,427...45,604,467
|
|
G |
Hsd3b1 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
susceptibility |
IEP ISO |
mRNA:decreased expression:ovary (rat) DNA:polymorphism:exon |
RGD |
PMID:19228890 PMID:12054649 |
RGD:4761326, RGD:1626438 |
NCBI chr 2:186,169,864...186,175,984
|
|
G |
Hsd3b2 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 |
|
IEP |
mRNA:increased expression:hypothalamus (rat) |
RGD |
PMID:16116051 |
RGD:1599701 |
NCBI chr 2:186,095,897...186,105,354
|
|
G |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
|
ISO |
mRNA: increased expression: leukocyte |
RGD |
PMID:17341625 |
RGD:6480224 |
NCBI chr 8:50,080,514...50,084,376
|
|
G |
Hspd1 |
heat shock protein family D (Hsp60) member 1 |
|
IEP |
mRNA:increased expression:brain, blood vessel |
RGD |
PMID:15729290 PMID:18948349 |
RGD:1624213, RGD:10402862 |
NCBI chr 9:64,073,610...64,084,332
|
|
G |
Hspg2 |
heparan sulfate proteoglycan 2 |
|
IEP |
mRNA:increased expression:aorta |
RGD |
PMID:8225534 |
RGD:1624258 |
NCBI chr 5:154,960,818...155,061,971
|
|
G |
Htr1b |
5-hydroxytryptamine receptor 1B |
|
IEP |
protein:increased expression:aorta |
RGD |
PMID:11882579 |
RGD:1626447 |
NCBI chr 8:91,395,405...91,414,815
|
|
G |
Htr2a |
5-hydroxytryptamine receptor 2A |
susceptibility no_association |
ISO |
DNA:polymorphism: :102T>C DNA:polymorphism: :g.102T>C |
RGD GAD |
PMID:11378836 PMID:15118671 PMID:15659047 |
RGD:1624375, RGD:1331525, RGD:1624371 |
NCBI chr15:56,360,647...56,428,703
|
|
G |
Htr2b |
5-hydroxytryptamine receptor 2B |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:8627522 |
|
NCBI chr 9:94,184,442...94,206,851
|
|
G |
Htra1 |
HtrA serine peptidase 1 |
|
ISO |
associated with Macular Degeneration; DNA:snp:cds:g.102C>T (rs1049331) (human) |
RGD |
PMID:21682878 |
RGD:7394697 |
NCBI chr 1:185,497,815...185,547,380
|
|
G |
Icam1 |
intercellular adhesion molecule 1 |
|
ISO |
associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:serum CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:12149661 PMID:12425201 PMID:18619052 |
RGD:2312765 |
NCBI chr 8:27,829,688...27,841,618
|
|
G |
Ier3 |
immediate early response 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20713914 |
|
NCBI chr20:2,933,173...2,934,377
|
|
G |
Igf1 |
insulin-like growth factor 1 |
severity |
ISO IEP IAGP |
mRNA:increased expression:aorta (rat) CTD Direct Evidence: marker/mechanism|therapeutic |
CTD RGD |
PMID:19502719 PMID:22228705 PMID:16431135 PMID:8418983 PMID:15996002 |
RGD:1598427, RGD:12904968, RGD:1580474 |
NCBI chr 7:24,169,608...24,249,446
|
|
G |
Igf1r |
insulin-like growth factor 1 receptor |
|
IEP |
protein:increased expression:aorta: |
RGD |
PMID:21854769 |
RGD:10046007 |
NCBI chr 1:130,959,787...131,248,664
|
|
G |
Igfbp2 |
insulin-like growth factor binding protein 2 |
|
IEP |
mRNA, protein:decreased expression:liver, plasma |
RGD |
PMID:9396554 |
RGD:1626482 |
NCBI chr 9:74,415,574...74,442,945
|
|
G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
treatment |
IEP ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:27659729 PMID:32147540 PMID:19246475 |
RGD:7495780 |
NCBI chr16:76,021,968...76,075,717
|
|
G |
Il10 |
interleukin 10 |
|
IEP |
|
RGD |
PMID:19398662 |
RGD:2311047 |
NCBI chr13:45,024,921...45,029,586
|
|
G |
Il17a |
interleukin 17A |
|
ISO |
protein:increased expression:blood serum (human) |
RGD |
PMID:26502942 |
RGD:329955577 |
NCBI chr 9:30,640,844...30,644,331
|
|
G |
Il1b |
interleukin 1 beta |
|
IEP ISO IDA |
mRNA, protein:increased expression:aorta, plasma CTD Direct Evidence: marker/mechanism associated with Obesity;protein:increased expression:plasma |
CTD RGD |
PMID:27292124 PMID:27659729 PMID:27847271 PMID:32147540 PMID:32165127 PMID:15894892 PMID:21173343 PMID:15990729 More...
|
RGD:1626635, RGD:7175338, RGD:1626638 |
NCBI chr 3:137,030,200...137,036,581
|
|
G |
Il1rn |
interleukin 1 receptor antagonist |
susceptibility |
IDA ISO |
DNA:polymorphisms |
RGD |
PMID:11585563 PMID:11840488 |
RGD:1626668, RGD:1626667 |
NCBI chr 3:27,509,836...27,525,738
|
|
G |
Il6 |
interleukin 6 |
susceptibility |
ISO |
associated with end stage renal disease; DNA:polymorphisms:promoter: -174G>C (human) protein:increased expression:blood serum (human) CTD Direct Evidence: marker/mechanism associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:extracellular space (human) |
CTD RGD |
PMID:27292124 PMID:27659729 PMID:27847271 PMID:32147540 PMID:32165127 PMID:12846758 PMID:26502942 PMID:19043252 More...
|
RGD:1580485, RGD:329955577, RGD:2307283 |
NCBI chr 4:5,889,999...5,894,575
|
|
G |
Il6r |
interleukin 6 receptor |
severity |
ISO |
Hypertension, Pregnancy-Induced;protein:increased expression:serum |
RGD |
PMID:11778537 |
RGD:1625432 |
NCBI chr 2:177,582,020...177,646,705
|
|
G |
Il6st |
interleukin 6 cytokine family signal transducer |
severity |
ISO |
Hypertension, Pregnancy-Induced;protein:increased expression:serum |
RGD |
PMID:11778537 |
RGD:1625432 |
NCBI chr 2:45,798,872...45,839,501
|
|
G |
Inppl1 |
inositol polyphosphate phosphatase-like 1 |
|
ISO |
DNA:SNPs: :rs2276047,snp8,rs9886(human) CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:15220217 PMID:15220217 |
RGD:1626127 |
NCBI chr 1:156,183,043...156,197,500
|
|
G |
Ins2 |
insulin 2 |
|
IDA ISO |
CTD Direct Evidence: marker/mechanism CTD Direct Evidence: marker/mechanism|therapeutic |
CTD RGD |
PMID:9719048 PMID:18360027 PMID:29211853 PMID:9095092 |
RGD:6902896 |
NCBI chr 1:207,272,738...207,421,998
|
|
G |
Invs |
inversin |
|
ISO |
associated with nephronophthisis 2; |
RGD |
PMID:19177160 |
RGD:155791686 |
NCBI chr 5:67,406,511...67,559,355
|
|
G |
Itga9 |
integrin subunit alpha 9 |
susceptibility |
ISO |
DNA:SNP: :rs155524(human) |
RGD |
PMID:20479155 |
RGD:13602005 |
NCBI chr 8:118,307,424...118,615,527
|
|
G |
Itgav |
integrin subunit alpha V |
|
IEP |
protein:increased expression:artery |
RGD |
PMID:16380536 |
RGD:1627642 |
NCBI chr 3:89,245,382...89,333,512
|
|
G |
Itm2b |
integral membrane protein 2B |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22228705 |
|
NCBI chr15:48,545,998...48,568,904
|
|
G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
|
IDA ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:24039778 PMID:11358932 |
RGD:10047414 |
NCBI chr 5:115,009,900...115,012,993
|
|
G |
Kcna3 |
potassium voltage-gated channel subfamily A member 3 |
|
ISO |
protein:increased activity:T cell (human) |
RGD |
PMID:24524604 |
RGD:401794566 |
NCBI chr 2:194,632,106...194,634,059
|
|
G |
Kcna5 |
potassium voltage-gated channel subfamily A member 5 |
|
IEP |
mRNA:increased expression:heart |
RGD |
PMID:11358947 |
RGD:1627659 |
NCBI chr 4:161,040,853...161,044,311
|
|
G |
Kcnab1 |
potassium voltage-gated channel subfamily A regulatory beta subunit 1 |
|
IEP |
mRNA:increased expression:aorta, arteries (rat) |
RGD |
PMID:11358947 |
RGD:1627659 |
NCBI chr 2:149,137,025...149,603,540
|
|
G |
Kcnj1 |
potassium inwardly-rectifying channel, subfamily J, member 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22228705 |
|
NCBI chr 8:30,779,883...30,808,607
|
|
G |
Kcnj11 |
potassium inwardly-rectifying channel, subfamily J, member 11 |
|
IEP |
|
RGD |
PMID:15964031 |
RGD:1598644 |
NCBI chr 1:105,727,473...105,731,167
|
|
G |
Kcnj8 |
potassium inwardly-rectifying channel, subfamily J, member 8 |
|
IDA |
|
RGD |
PMID:16051697 |
RGD:1581698 |
NCBI chr 4:175,508,908...175,515,829
|
|
G |
Kcnmb1 |
potassium calcium-activated channel subfamily M regulatory beta subunit 1 |
|
IDA ISO IEP |
CTD Direct Evidence: marker/mechanism mRNA, protein:increased expression:aorta, mesenteric artery |
CTD RGD |
PMID:17700361 PMID:14551242 PMID:16814121 PMID:16293791 |
RGD:1298970, RGD:10412046, RGD:1581718 |
NCBI chr10:19,062,014...19,119,005
|
|
G |
Kcnn4 |
potassium calcium-activated channel subfamily N member 4 |
ameliorates |
ISO IMP |
mRNA, protein:increased expression:CD4-positive, alpha-beta T cell (human) associated with Cardiac Fibrosis protein:increased activity:T cell (human) |
RGD |
PMID:26502942 PMID:25715999 PMID:24524604 |
RGD:329955577, RGD:401794570, RGD:401794566 |
NCBI chr 1:79,956,380...79,974,354
|
|
G |
Kcnq1 |
potassium voltage-gated channel subfamily Q member 1 |
|
IAGP |
DNA:deletion:exon (rat) |
RGD |
PMID:16368876 |
RGD:1581602 |
NCBI chr 1:207,721,134...208,054,073
|
|
G |
Kcnq1dfk |
potassium voltage-gated channel subfamily Q member 1;deafness Kyoto |
|
IAGP |
|
RGD |
PMID:16368876 |
RGD:1581602 |
|
|
G |
Kdr |
kinase insert domain receptor |
treatment |
IEP ISO |
DNA:polymorphism:cds:p.H472Q(human) |
RGD |
PMID:15838270 PMID:20630084 |
RGD:5684418, RGD:8552374 |
NCBI chr14:32,572,031...32,615,204
|
|
G |
Kif6 |
kinesin family member 6 |
susceptibility |
ISO |
DNA:SNP, haplotype: :rs20455 (p.W719R), rs6930913 (human) |
RGD |
PMID:34961832 |
RGD:243048456 |
NCBI chr 9:11,076,203...11,373,205
|
|
G |
Kl |
Klotho |
treatment |
IDA IEP ISO |
mRNA,protein:decreased expression:kidney: |
RGD |
PMID:10892340 PMID:21051829 PMID:23225045 |
RGD:1581732, RGD:10403063, RGD:10403062 |
NCBI chr12:490,402...531,417
|
|
G |
Klk1 |
kallikrein 1 |
no_association susceptibility |
ISO IEP |
DNA:polymorphisms CTD Direct Evidence: therapeutic mRNA:decreased expression:kidney |
RGD CTD |
PMID:14568997 PMID:15905889 PMID:15167446 PMID:15809361 |
RGD:1641795, RGD:1581751, RGD:1358144 |
NCBI chr 1:94,642,644...94,646,760
|
|
G |
Klk1b3 |
kallikrein 1-related peptidase B3 |
|
IAGP |
|
RGD |
PMID:15809361 |
RGD:1358144 |
NCBI chr 1:94,709,105...94,713,308
|
|
G |
Klk1c12 |
kallikrein 1-related peptidase C12 |
|
ISO |
DNA:polymorphisms |
RGD |
PMID:15905889 PMID:17272402 |
RGD:1641795, RGD:1641794 |
NCBI chr 1:94,378,103...94,382,140
|
|
G |
Klkb1 |
kallikrein B1 |
|
ISO |
associated with Diabetes Mellitus, Type 1; protein:increased expression:plasma: |
RGD |
PMID:12716755 |
RGD:7327151 |
NCBI chr16:46,958,634...46,982,054
|
|
G |
Kng1 |
kininogen 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:7027322 |
|
NCBI chr11:77,812,757...77,835,555
|
|
G |
Kras |
KRAS proto-oncogene, GTPase |
|
ISO |
|
RGD |
PMID:15864294 |
RGD:1581757 |
NCBI chr 4:179,916,255...179,949,613
|
|
G |
Kynu |
kynureninase |
|
IAGP |
|
RGD |
PMID:11924719 |
RGD:631322 |
NCBI chr 3:48,188,286...48,338,996
|
|
G |
Ldha |
lactate dehydrogenase A |
treatment |
IEP |
|
RGD |
PMID:31572179 |
RGD:329956417 |
NCBI chr 1:97,371,823...97,381,247
|
|
G |
Lep |
leptin |
|
ISO IDA |
DNA:SNPs: : CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:12050272 PMID:16827954 PMID:25205467 PMID:27226618 PMID:19204185 PMID:20059648 More...
|
RGD:5128788, RGD:5128597 |
NCBI chr 4:58,626,529...58,640,663
|
|
G |
Lepr |
leptin receptor |
disease_progression |
ISO IAGP IMP |
DNA:polymorphisms:exons DNA:mutations:cds: : (rat) CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:22949526 PMID:10999797 PMID:32710530 PMID:27465994 |
RGD:5129161, RGD:401960103, RGD:12911217 |
NCBI chr 5:121,409,735...121,593,201
|
|
G |
Leprem2Mcwi |
leptin receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin |
disease_progression |
IMP |
|
RGD |
PMID:27465994 |
RGD:12911217 |
|
|
G |
Lgals3 |
galectin 3 |
treatment |
IEP |
|
RGD |
PMID:23117656 |
RGD:9685203 |
NCBI chr15:20,620,083...20,632,019
|
|
G |
Lhb |
luteinizing hormone subunit beta |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:6350720 |
|
NCBI chr 1:105,037,457...105,038,446
|
|
G |
Lipe |
lipase E, hormone sensitive type |
|
ISO |
gestational hypertension;DNA:polymorphism:promoter:-60C>G |
RGD |
PMID:17318300 |
RGD:1625026 |
NCBI chr 1:80,965,612...80,984,313
|
|
G |
Lipg |
lipase G, endothelial type |
|
IDA |
|
RGD |
PMID:15914124 |
RGD:1581875 |
NCBI chr18:68,514,923...68,536,105
|
|
G |
Lox |
lysyl oxidase |
|
ISO IDA |
|
RGD |
PMID:8562290 PMID:24127 |
RGD:1581896, RGD:1581899 |
NCBI chr18:45,964,544...45,977,431
|
|
G |
Lpl |
lipoprotein lipase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:22228705 PMID:16132104 |
RGD:1580535 |
NCBI chr16:25,596,205...25,621,928
|
|
G |
Lrp2 |
LDL receptor related protein 2 |
|
IDA |
protein:altered localization:apical plasma membrane |
RGD |
PMID:10919857 |
RGD:1641827 |
NCBI chr 3:54,189,305...54,346,769
|
|
G |
Lta |
lymphotoxin alpha |
no_association |
ISO |
|
RGD |
PMID:15533732 |
RGD:1580415 |
NCBI chr20:3,622,291...3,625,852
|
|
G |
Ltf |
lactotransferrin |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:24587916 |
|
NCBI chr 8:110,999,948...111,022,795
|
|
G |
Map1lc3a |
microtubule-associated protein 1 light chain 3 alpha |
|
IEP |
|
RGD |
PMID:23499735 |
RGD:11561939 |
NCBI chr 3:164,243,204...164,244,850
|
|
G |
Mapk8 |
mitogen-activated protein kinase 8 |
|
IDA |
|
RGD |
PMID:15302844 |
RGD:1582315 |
NCBI chr16:8,645,171...8,728,225
|
|
G |
Mas1 |
MAS1 proto-oncogene, G protein-coupled receptor |
|
IMP |
associated with Sleep Apnea Syndromes |
RGD |
PMID:21040717 |
RGD:5129169 |
NCBI chr 1:50,428,064...50,459,537
|
|
G |
Mc2r |
melanocortin 2 receptor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:11082157 |
|
NCBI chr18:62,001,980...62,015,567
|
|
G |
Mdh1 |
malate dehydrogenase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22228705 |
|
NCBI chr14:95,630,625...95,645,920
|
|
G |
Mfn2 |
mitofusin 2 |
treatment |
IEP |
protein:decreased expression:aorta (rat) |
RGD |
PMID:27847271 PMID:25464244 |
RGD:12910764, RGD:13204764 |
NCBI chr 5:158,304,285...158,335,502
|
|
G |
Mif |
macrophage migration inhibitory factor |
|
IDA |
|
RGD |
PMID:19799867 |
RGD:4890974 |
NCBI chr20:12,790,919...12,791,784
|
|
G |
Mir145 |
microRNA 145 |
|
ISO |
miRNA:increased expression:artery wall (human) |
RGD |
PMID:23339529 |
RGD:155260305 |
NCBI chr18:57,369,983...57,370,070
|
|
G |
Mir214 |
microRNA 214 |
treatment |
IMP ISO |
RNA:increased expression:kidney |
RGD |
PMID:30049682 PMID:30049682 |
RGD:38500245, RGD:38500245 |
NCBI chr13:74,588,374...74,588,481
|
|
G |
Mme |
membrane metallo-endopeptidase |
treatment |
IMP |
|
RGD |
PMID:12011651 |
RGD:13801039 |
NCBI chr 2:149,806,826...149,957,381
|
|
G |
Mmp1 |
matrix metallopeptidase 1 |
|
ISO |
protein:decreased expression:renal glomerulus (human) |
RGD |
PMID:15363819 PMID:19506087 |
RGD:1582532, RGD:2312464 |
NCBI chr 8:12,943,453...12,963,966
|
|
G |
Mmp2 |
matrix metallopeptidase 2 |
|
IEP ISO |
mRNA, protein:increased expression:kidney CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:18836702 PMID:17977875 PMID:16840178 |
RGD:2290351, RGD:1582612 |
NCBI chr19:30,327,643...30,355,856
|
|
G |
Mmp7 |
matrix metallopeptidase 7 |
treatment |
IMP IEP |
|
RGD |
PMID:19398663 PMID:19398663 |
RGD:9685347, RGD:9685347 |
NCBI chr 8:13,133,043...13,140,761
|
|
G |
Mmp9 |
matrix metallopeptidase 9 |
susceptibility |
ISO IEP |
protein:decreased expression:internal mammary artery CTD Direct Evidence: marker/mechanism associated with Aneurysm, Dissecting;DNA:polymorphism:promoter:-1562C>T |
CTD RGD |
PMID:21051829 PMID:15363819 PMID:16780738 PMID:16840178 PMID:17977875 |
RGD:1582532, RGD:1642029, RGD:1582612, RGD:2290351 |
NCBI chr 3:174,103,474...174,111,434
|
|
G |
Mov10 |
Mov10 RNA helicase |
susceptibility |
ISO |
DNA:SNP: :rs2932538(human) |
RGD |
PMID:24338417 |
RGD:13513987 |
NCBI chr 2:192,292,041...192,315,142
|
|
G |
Moxd2 |
monooxygenase, DBH-like 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:3814904 |
|
NCBI chr 4:69,724,693...69,733,188
|
|
G |
Msx2 |
msh homeobox 2 |
|
IEP |
|
RGD |
PMID:18270471 |
RGD:5132616 |
NCBI chr17:11,097,214...11,102,879
|
|
G |
Mtor |
mechanistic target of rapamycin kinase |
|
IDA ISO |
protein:increased serine phosphorylation:kidney CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:19289642 PMID:23323219 |
RGD:10041025 |
NCBI chr 5:164,167,985...164,277,438
|
|
G |
Mtpn |
myotrophin |
|
IEP IDA |
|
RGD |
PMID:12419325 PMID:12031792 |
RGD:632799, RGD:1581046 |
NCBI chr 4:64,159,273...64,186,686
|
|
G |
Mtr |
5-methyltetrahydrofolate-homocysteine methyltransferase |
|
ISO |
|
RGD |
PMID:15148588 |
RGD:1581050 |
NCBI chr17:62,911,705...62,996,544
|
|
G |
Mttp |
microsomal triglyceride transfer protein |
onset |
ISO |
DNA:polymorphism:promoter:-493G>T |
RGD |
PMID:16328015 |
RGD:1625485 |
NCBI chr 2:226,613,090...226,654,239
|
|
G |
Mybph |
myosin binding protein H |
|
IAGP |
DNA:missense mutations:cds:p.I?T, p.R?K (rat) |
RGD |
PMID:23460292 |
RGD:12802369 |
NCBI chr13:45,653,156...45,660,893
|
|
G |
Myd88 |
MYD88, innate immune signal transduction adaptor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27292124 |
|
NCBI chr 8:127,952,161...127,956,230
|
|
G |
Myh7 |
myosin heavy chain 7 |
|
IEP ISO |
protein:decreased expression:heart left ventricle, arteriole CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:32147540 PMID:9686760 |
RGD:9835388 |
NCBI chr15:32,416,525...32,439,851
|
|
G |
Myo6 |
myosin VI |
|
IDA |
protein:altered localization:renal proximal tubule, microvillus |
RGD |
PMID:16107581 |
RGD:2314963 |
NCBI chr 8:81,087,157...81,242,022
|
|
G |
Myod1 |
myogenic differentiation 1 |
|
IEP |
mRNA:decreased expression:gastrocnemius |
RGD |
PMID:22076133 |
RGD:9686076 |
NCBI chr 1:106,021,161...106,023,871
|
|
G |
Ncf1 |
neutrophil cytosolic factor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16331104 PMID:17324946 PMID:19018797 PMID:32165127 |
|
NCBI chr12:28,121,816...28,131,080
|
|
G |
Ncf2 |
neutrophil cytosolic factor 2 |
|
IEP |
protein:increased expression:heart left ventricle |
RGD |
PMID:19307699 |
RGD:2314430 |
NCBI chr13:67,505,492...67,536,015
|
|
G |
Nedd4l |
NEDD4 like E3 ubiquitin protein ligase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18524855 PMID:23348737 |
|
NCBI chr18:58,393,759...58,726,709
|
|
G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
treatment |
IEP ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:32165127 PMID:23775684 PMID:23528973 |
RGD:10412717, RGD:401793732 |
NCBI chr 3:81,001,529...81,031,165
|
|
G |
Nfkbia |
NFKB inhibitor alpha |
treatment |
IEP |
|
RGD |
PMID:19246475 |
RGD:7495780 |
NCBI chr 6:78,593,844...78,597,307
|
|
G |
Ngf |
nerve growth factor |
|
IEP |
|
RGD |
PMID:10797303 |
RGD:5144109 |
NCBI chr 2:192,589,580...192,642,971
|
|
G |
Ngfr |
nerve growth factor receptor |
|
IAGP |
DNA,protein:missense mutation:CDS:c.28G>A, p.A10T (rat strains: SHR/Izm, SHRSP/Izm, WKHT) |
RGD |
PMID:8762194 |
RGD:5508800 |
NCBI chr10:81,012,077...81,030,305
|
|
G |
Nherf1 |
NHERF family PDZ scaffold protein 1 |
|
IEP |
|
RGD |
PMID:15311100 |
RGD:1580741 |
NCBI chr10:100,403,189...100,420,290
|
|
G |
Nherf2 |
NHERF family PDZ scaffold protein 2 |
|
IEP ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:22228705 PMID:15311100 |
RGD:1580741 |
NCBI chr10:13,662,461...13,672,975
|
|
G |
Nisch |
nischarin |
|
IMP |
|
RGD |
PMID:12021582 |
RGD:1581128 |
NCBI chr16:6,370,809...6,407,104
|
|
G |
Nos1 |
nitric oxide synthase 1 |
treatment |
IEP IDA IMP |
mRNA:decreased expression:bladder, penis |
RGD |
PMID:17574276 PMID:31489946 PMID:23201071 PMID:15913838 PMID:16093913 PMID:15775788 PMID:20494920 More...
|
RGD:1642127, RGD:401793758, RGD:7257668, RGD:1581142, RGD:1581141, RGD:1581143, RGD:5132600 |
NCBI chr12:44,276,011...44,456,371
|
|
G |
Nos2 |
nitric oxide synthase 2 |
|
IEP ISO |
protein:increased expression, increased activity:kidney CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:18605955 PMID:25101153 PMID:27292124 PMID:15773227 PMID:11702222 |
RGD:1580264, RGD:1298023 |
NCBI chr10:64,313,335...64,349,221
|
|
G |
Nos3 |
nitric oxide synthase 3 |
treatment no_association |
IEP IDA ISO |
associated with Pregnancy Complications CTD Direct Evidence: marker/mechanism|therapeutic DNA:duplication, snp:intron, cds:IVS4?-?+27, p.E298D (human) DNA:snp:cds:p.E298D (human) protein:decreased phosphorylation:brain |
CTD RGD |
PMID:11457755 PMID:12947532 PMID:16331104 PMID:19008412 PMID:19407804 PMID:18047920 PMID:31489946 PMID:29285068 PMID:29084084 PMID:10981549 PMID:11882615 PMID:9674630 PMID:20813549 More...
|
RGD:2292113, RGD:401793758, RGD:13504683, RGD:13446414, RGD:1580278, RGD:1580271, RGD:1580282, RGD:4891993 |
NCBI chr 4:11,686,088...11,706,604
|
|
G |
Nox1 |
NADPH oxidase 1 |
ameliorates |
ISO |
|
RGD |
PMID:16246966 |
RGD:329955580 |
NCBI chr X:97,279,058...97,332,291
|
|
G |
Nox4 |
NADPH oxidase 4 |
|
IEP ISO IMP |
protein:increased expression:aorta, vascular associated smooth muscle cell CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:27659729 PMID:27847271 PMID:32147540 PMID:18418428 PMID:26644237 |
RGD:2324669, RGD:11085830 |
NCBI chr 1:150,313,736...150,491,480
|
|
G |
Nphp3 |
nephrocystin 3 |
|
ISO |
associated with nephronophthisis; |
RGD |
PMID:19177160 |
RGD:155791686 |
NCBI chr 8:113,500,708...113,541,179
|
|
G |
Nppa |
natriuretic peptide A |
|
IEP ISS ISO |
protein:increased expression:plasma: CTD Direct Evidence: marker/mechanism|therapeutic |
MouseDO CTD RGD |
PMID:2526952 PMID:7839143 PMID:8188982 PMID:9869009 PMID:12940879 PMID:19219041 PMID:24039778 PMID:32147540 PMID:20139323 More...
|
RGD:7248593 |
NCBI chr 5:163,712,184...163,713,493
|
|
G |
Nppb |
natriuretic peptide B |
treatment susceptibility |
IEP ISO IDA |
CTD Direct Evidence: marker/mechanism|therapeutic DNA:repeats |
CTD RGD |
PMID:9194512 PMID:19219041 PMID:24039778 PMID:30310171 PMID:32147540 PMID:11897768 PMID:21403100 PMID:17554401 More...
|
RGD:70484, RGD:5685657, RGD:1642191 |
NCBI chr 5:163,699,955...163,701,314
|
|
G |
Nppc |
natriuretic peptide C |
severity |
ISO |
associated with Pregnancy Complications;protein:increased expression:plasma |
RGD |
PMID:11775888 PMID:12452325 |
RGD:1642292, RGD:1580150 |
NCBI chr 9:94,767,986...94,772,186
|
|
G |
Npr1 |
natriuretic peptide receptor 1 |
|
IAGP ISO |
DNA:repeat:promoter: (rat) CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:20881240 PMID:12511524 |
RGD:628585 |
NCBI chr 2:178,231,766...178,247,591
|
|
G |
Npr3 |
natriuretic peptide receptor 3 |
|
ISO |
DNA:snp:promoter:g.-55C>A (human) |
RGD |
PMID:12872042 |
RGD:1580175 |
NCBI chr 2:60,865,483...60,933,432
|
|
G |
Nptn |
neuroplastin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22228705 |
|
NCBI chr 8:58,996,873...59,063,402
|
|
G |
Npy |
neuropeptide Y |
|
IMP IEP ISO |
DNA:missense mutation:cds:p.L7P (human) |
RGD |
PMID:15699473 PMID:18835922 PMID:11689216 |
RGD:1357410, RGD:10448968, RGD:1580177 |
NCBI chr 4:80,212,111...80,219,310
|
|
G |
Npy1r |
neuropeptide Y receptor Y1 |
|
IMP |
|
RGD |
PMID:15699473 |
RGD:1357410 |
NCBI chr16:27,804,416...27,814,070
|
|
G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
treatment susceptibility |
IDA ISO |
DNA:SNP,haplotype:: p.P187S (rs1800566) (human) |
RGD |
PMID:25529925 PMID:21502369 |
RGD:401827819, RGD:11035215 |
NCBI chr19:52,205,374...52,220,267
|
|
G |
Nr2f2 |
nuclear receptor subfamily 2, group F, member 2 |
|
IMP |
|
RGD |
PMID:25687237 |
RGD:10401852 |
NCBI chr 1:133,419,161...133,434,290
|
|
G |
Nr2f2em1Mcwi |
nuclear receptor subfamily 2, group F, member 2; zinc finger nuclease induced mutant 1, Medical College of Wisconsin |
|
IMP |
|
RGD |
PMID:25687237 |
RGD:10401852 |
|
|
G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
|
IMP ISO |
associated with fetal nutrition disorder CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:18434569 PMID:20659135 PMID:20674672 PMID:20659135 |
RGD:4892208, RGD:7174714 |
NCBI chr18:31,522,783...31,644,508
|
|
G |
Ntm |
neurotrimin |
treatment |
ISO |
DNA:SNPs: :rs2511774, rs139945292, rs80175218 |
RGD |
PMID:34231218 |
RGD:596948394 |
NCBI chr 8:27,376,582...28,366,604
|
|
G |
Nudt1 |
nudix hydrolase 1 |
|
IEP |
|
RGD |
PMID:17280880 |
RGD:10449166 |
NCBI chr12:14,302,514...14,309,559
|
|
G |
Ogg1 |
8-oxoguanine DNA glycosylase |
susceptibility |
ISO |
DNA:SNP,haplotype::p.S326C (rs1052133) (human) |
RGD |
PMID:25529925 |
RGD:401827819 |
NCBI chr 4:148,030,237...148,037,599
|
|
G |
Olr1 |
oxidized low density lipoprotein receptor 1 |
|
IEP ISO |
mRNA:increased expression:aorta (rat) CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:22352330 PMID:9494115 |
RGD:633385 |
NCBI chr 4:164,612,460...164,635,082
|
|
G |
Opa1 |
OPA1, mitochondrial dynamin like GTPase |
|
IEP |
protein:increased expression:heart left ventricle (rat) |
RGD |
PMID:24388463 |
RGD:7800726 |
NCBI chr11:84,612,943...84,690,025
|
|
G |
Orai1 |
ORAI calcium release-activated calcium modulator 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19897708 |
|
NCBI chr12:39,195,139...39,209,030
|
|
G |
Oxsr1 |
oxidative stress responsive kinase 1 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:22949526 |
|
NCBI chr 8:127,850,481...127,941,518
|
|
G |
Oxt |
oxytocin/neurophysin I prepropeptide |
|
IMP ISO IEP |
CTD Direct Evidence: therapeutic mRNA:decreased expression:paraventricular hypothalamic nucleus |
CTD RGD |
PMID:9334988 PMID:18562099 PMID:18562099 PMID:16157794 |
RGD:2304105, RGD:2304174 |
NCBI chr 3:117,782,650...117,783,490
|
|
G |
Oxtr |
oxytocin receptor |
|
IEP |
mRNA:decreased expression:brainstem |
RGD |
PMID:16157794 |
RGD:2304174 |
NCBI chr 4:147,154,374...147,171,723
|
|
G |
Pappa |
pappalysin |
|
ISO |
associated with Pregnancy Complications, Cardiovascular;protein:decreased expression:serum |
RGD |
PMID:12224070 |
RGD:1642331 |
NCBI chr 5:78,497,660...78,735,873
|
|
G |
Pdgfb |
platelet derived growth factor subunit B |
|
IEP |
|
RGD |
PMID:8869081 |
RGD:10449484 |
NCBI chr 7:113,419,882...113,438,343
|
|
G |
Pdgfra |
platelet derived growth factor receptor alpha |
|
IEP |
|
RGD |
PMID:1657776 |
RGD:11080972 |
NCBI chr14:33,360,027...33,408,604
|
|
G |
Pdgfrb |
platelet derived growth factor receptor beta |
|
IEP |
protein:increased tyrosine phosphorylation:glomerulus |
RGD |
PMID:12047046 PMID:1657776 |
RGD:2292214, RGD:11080972 |
NCBI chr18:56,770,348...56,809,228
|
|
G |
Pgf |
placental growth factor |
|
ISO |
associated with Pregnancy Complications, Cardiovascular;mRNA:decreased expression:placenta |
RGD |
PMID:12808329 |
RGD:1642387 |
NCBI chr 6:110,547,165...110,557,747
|
|
G |
Pik3r1 |
phosphoinositide-3-kinase regulatory subunit 1 |
|
IEP IMP |
protein:decreased expression:ventricular myocyte (rat) |
RGD |
PMID:18300869 PMID:19015400 |
RGD:4108492, RGD:4108483 |
NCBI chr 2:34,612,946...34,697,660
|
|
G |
Pin1 |
peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
|
ISO |
|
RGD |
PMID:21810655 |
RGD:8693428 |
NCBI chr 8:27,465,538...27,477,016
|
|
G |
Pkd1 |
polycystin 1, transient receptor potential channel interacting |
|
ISO |
ClinVar Annotator: match by term: Hypertension |
ClinVar |
PMID:11115377 PMID:12482949 PMID:16430766 PMID:17574468 PMID:17582161 PMID:22508176 PMID:23064367 PMID:23431072 PMID:23760289 PMID:24694054 PMID:25333066 PMID:25741868 PMID:26467025 PMID:26632257 PMID:26950445 PMID:27499327 PMID:29633482 PMID:29801666 PMID:30333007 PMID:31056860 PMID:31738409 PMID:32203225 PMID:32381729 PMID:33315352 PMID:33437386 PMID:33532864 PMID:36646975 More...
|
|
NCBI chr10:13,573,779...13,621,138
|
|
G |
Pkm |
pyruvate kinase M1/2 |
treatment |
IEP |
|
RGD |
PMID:31572179 |
RGD:329956417 |
NCBI chr 8:68,949,731...68,975,394
|
|
G |
Plat |
plasminogen activator, tissue type |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22352330 |
|
NCBI chr16:75,943,061...76,022,037
|
|
G |
Plcd1 |
phospholipase C, delta 1 |
|
IEP IDA |
protein:increased expression:aorta, arteriole, glomerulus protein:increased activity:aorta |
RGD |
PMID:17198910 PMID:1313006 |
RGD:2300421, RGD:2300423 |
NCBI chr 8:118,795,196...118,818,186
|
|
G |
Plekha7 |
pleckstrin homology domain containing A7 |
ameliorates |
IMP |
|
RGD |
PMID:25136115 |
RGD:11079199 |
NCBI chr 1:170,364,524...170,547,843
|
|
G |
Plekha7em4Mcwi |
pleckstrin homology domain containing, family A member 7; zinc finger nuclease induced mutant 4, Medical College of Wisconsin |
ameliorates |
IMP |
|
RGD |
PMID:25136115 |
RGD:11079199 |
|
|
G |
Plg |
plasminogen |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:6383834 |
|
NCBI chr 1:48,325,186...48,367,643
|
|
G |
Pnmt |
phenylethanolamine-N-methyltransferase |
no_association |
ISO IEP |
DNA:snps:5' utr:g.-390G>A, g.-184G>A rs876493 (human) protein:decreased activity:adrenal gland (rat) DNA:snp:5' utr:g.-390G>A (human) |
RGD |
PMID:17645789 PMID:20378607 PMID:14553966 |
RGD:5130172, RGD:5130152, RGD:5130164 |
NCBI chr10:83,881,211...83,882,849
|
|
G |
Pomc |
proopiomelanocortin |
|
ISO |
CTD Direct Evidence: marker/mechanism|therapeutic |
CTD |
PMID:76749 PMID:187612 PMID:216942 PMID:323586 PMID:1316127 PMID:1321011 PMID:1321309 PMID:1327015 PMID:1330390 PMID:1334993 PMID:1649024 PMID:1664305 PMID:2157753 PMID:2455169 PMID:2551692 PMID:2821097 PMID:2822310 PMID:2849322 PMID:2992854 PMID:3001556 PMID:3015460 PMID:4367732 PMID:6088243 PMID:6089027 PMID:6097376 PMID:6100240 PMID:6135010 PMID:6143199 PMID:6254450 PMID:6274577 PMID:6279500 PMID:6283272 PMID:8136112 PMID:8261660 PMID:8279378 PMID:8713685 PMID:8800598 PMID:9056691 PMID:9535146 PMID:10100081 PMID:10474778 PMID:10513829 PMID:10658937 PMID:11071300 PMID:11071304 PMID:11132610 PMID:11193135 PMID:11518849 PMID:11560123 PMID:11703388 PMID:12872045 PMID:12887135 PMID:15110907 PMID:15132301 PMID:15554453 PMID:16053986 PMID:16243970 PMID:16546835 PMID:16620303 PMID:17324744 PMID:17954371 PMID:17994356 PMID:18067589 PMID:18487447 PMID:19153526 PMID:19458537 PMID:20186125 PMID:20659135 More...
|
|
NCBI chr 6:32,659,137...32,665,175
|
|
G |
Pon1 |
paraoxonase 1 |
|
ISO |
DNA:SNP: :rs705379 (human) |
RGD |
PMID:32034489 |
RGD:401827127 |
NCBI chr 4:34,261,312...34,292,327
|
|
G |
Postn |
periostin |
|
IEP |
associated with Renal Insufficiency, Chronic; protein:increased expression:left ventricle: |
RGD |
PMID:21712488 |
RGD:10041050 |
NCBI chr 2:140,677,774...140,709,304
|
|
G |
Ppara |
peroxisome proliferator activated receptor alpha |
treatment |
IEP ISO IMP |
mRNA:increased expression:skeletal muscle CTD Direct Evidence: marker/mechanism|therapeutic |
CTD RGD |
PMID:16054168 PMID:19834340 PMID:19763017 PMID:31489946 PMID:15967866 |
RGD:2313778, RGD:401793758, RGD:1580222 |
NCBI chr 7:118,712,261...118,780,723
|
|
G |
Pparg |
peroxisome proliferator-activated receptor gamma |
|
IMP ISO IEP IDA |
CTD Direct Evidence: marker/mechanism|therapeutic protein:decreased expression:rostral ventrolateral medulla (rat) human gene in a mouse model |
CTD RGD |
PMID:15199296 PMID:19666838 PMID:27292124 PMID:18437150 PMID:20404217 PMID:18316027 PMID:12923396 PMID:15970297 More...
|
RGD:2301888, RGD:7175297, RGD:2301864, RGD:1580690, RGD:1580684 |
NCBI chr 4:150,095,743...150,221,104
|
|
G |
Ppbp |
pro-platelet basic protein |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:6192689 PMID:15513305 |
|
NCBI chr14:17,586,495...17,587,299
|
|
G |
Ppia |
peptidylprolyl isomerase A |
|
ISO |
mRNA:increased expression:alveolar system (human) |
RGD |
PMID:32496587 |
RGD:150383342 |
NCBI chr14:81,279,292...81,282,960
|
|
G |
Prkag2 |
protein kinase AMP-activated non-catalytic subunit gamma 2 |
|
ISO |
ClinVar Annotator: match by term: Hypertension |
ClinVar |
PMID:25741868 PMID:28492532 |
|
NCBI chr 4:10,744,695...10,985,939
|
|
G |
Prkar1b |
protein kinase cAMP-dependent type I regulatory subunit beta |
|
ISO |
|
RGD |
PMID:11161799 |
RGD:619653 |
NCBI chr12:15,492,233...15,624,942
|
|
G |
Prkca |
protein kinase C, alpha |
|
IAGP |
|
RGD |
PMID:15792354 |
RGD:1581271 |
NCBI chr10:93,388,991...93,787,617
|
|
G |
Prkcb |
protein kinase C, beta |
|
IDA |
|
RGD |
PMID:15804434 |
RGD:1625513 |
NCBI chr 1:186,263,397...186,594,743
|
|
G |
Prkcd |
protein kinase C, delta |
|
IEP ISO IAGP |
protein:increased expression:heart, fibroblast CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:23973649 PMID:10756122 PMID:15792354 |
RGD:1642534, RGD:1581271 |
NCBI chr16:5,775,681...5,806,122
|
|
G |
Prkce |
protein kinase C, epsilon |
|
IAGP |
|
RGD |
PMID:15792354 |
RGD:1581271 |
NCBI chr 6:13,718,050...14,204,931
|
|
G |
Prkg1 |
protein kinase cGMP-dependent 1 |
|
IEP |
mRNA, protein:splice variant, alternative form:basilar artery |
RGD |
PMID:14512447 |
RGD:7775067 |
NCBI chr 1:237,818,950...239,052,184
|
|
G |
Prlhr |
prolactin releasing hormone receptor |
|
ISO |
DNA:SNP, missense mutation:promoter, cds:-62G>A, 914C>T (p.P305L) (human) |
RGD |
PMID:14691196 |
RGD:1641832 |
NCBI chr 1:259,606,704...259,608,391
|
|
G |
Proc |
protein C, inactivator of coagulation factors Va and VIIIa |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22352330 |
|
NCBI chr18:24,038,596...24,049,061
|
|
G |
Pten |
phosphatase and tensin homolog |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15646324 |
|
NCBI chr 1:240,043,707...240,110,330
|
|
G |
Ptgds |
prostaglandin D2 synthase |
|
ISO |
protein:increased expression:serum, urine |
RGD |
PMID:11882588 |
RGD:1642584 |
NCBI chr 3:28,680,044...28,682,978
|
|
G |
Ptgis |
prostaglandin I2 synthase |
susceptibility |
ISO IEP |
mRNA:increased expression:aortic endothelial cell (rat) DNA:repeat:promoter:g.-6(CCGCCAGCC)3-4 (human) DNA:SNP:exon 8:g.1117C>A (rs6095558) (human) |
RGD |
PMID:12372404 PMID:18056786 PMID:10577996 PMID:17070428 |
RGD:1298040, RGD:401960082, RGD:401959586, RGD:401959383 |
NCBI chr 3:155,928,564...155,964,228
|
|
G |
Ptgr1 |
prostaglandin reductase 1 |
|
IEP |
mRNA:decreased expression:rostral ventrolateral medulla, paraventricular nucleus of hypothalamus, nucleus of solitary tract (rat) |
RGD |
PMID:23172924 |
RGD:401959217 |
NCBI chr 5:78,579,060...78,597,671
|
|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
|
IAGP ISO |
CTD Direct Evidence: marker/mechanism|therapeutic |
CTD RGD |
PMID:14757778 PMID:15834289 PMID:20667508 PMID:22349312 PMID:15775781 PMID:16467505 More...
|
RGD:1581285, RGD:1580671 |
NCBI chr13:64,714,063...64,722,320
|
|
G |
Pth |
parathyroid hormone |
|
ISO |
protein:increased expression:serum (human) CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:1930854 PMID:23460043 |
RGD:7242420 |
NCBI chr 1:176,942,901...176,946,034
|
|
G |
Ptk2 |
protein tyrosine kinase 2 |
|
IAGP IEP |
protein:increased expression:aorta |
RGD |
PMID:12732587 PMID:21068519 |
RGD:729831, RGD:10041072 |
NCBI chr 7:107,015,730...107,220,865
|
|
G |
Ptk2b |
protein tyrosine kinase 2 beta |
susceptibility |
ISO IEP |
DNA:polymorphism:promoter:-22A>G protein:increased expression:aorta |
RGD |
PMID:18075463 PMID:21068519 |
RGD:2292575, RGD:10041072 |
NCBI chr15:44,536,275...44,656,754
|
|
G |
Ptpn1 |
protein tyrosine phosphatase, non-receptor type 1 |
treatment |
ISO IEP |
CTD Direct Evidence: therapeutic associated with obesity |
CTD RGD |
PMID:28899902 PMID:29859467 PMID:29562733 |
RGD:401976391, RGD:401976390 |
NCBI chr 3:156,638,811...156,687,503
|
|
G |
Ptprc |
protein tyrosine phosphatase, receptor type, C |
ameliorates |
IEP |
associated with Cardiac Fibrosis |
RGD |
PMID:25715999 |
RGD:401794570 |
NCBI chr13:52,147,717...52,259,810
|
|
G |
Ptprd |
protein tyrosine phosphatase, receptor type, D |
treatment |
ISO |
DNA:SNP:enhancer: (rs10739150) (human) |
RGD |
PMID:26425837 |
RGD:11085524 |
NCBI chr 5:90,046,993...90,698,977 NCBI chr 5:91,122,354...91,641,754
|
|
G |
Ptprj |
protein tyrosine phosphatase, receptor type, J |
|
IAGP |
|
RGD |
PMID:15710778 |
RGD:1357414 |
NCBI chr 3:96,861,785...97,017,702
|
|
G |
Ptpru |
protein tyrosine phosphatase, receptor type, U |
susceptibility |
ISO |
|
RGD |
PMID:11086029 |
RGD:1642652 |
NCBI chr 5:143,950,542...144,024,791
|
|
G |
Qdpr |
quinoid dihydropteridine reductase |
|
IEP |
protein:decreased expression:aorta smooth muscle (rat) |
RGD |
PMID:19743417 |
RGD:5128580 |
NCBI chr14:65,670,251...65,683,853
|
|
G |
Rad51 |
RAD51 recombinase |
treatment |
IDA |
|
RGD |
PMID:24239235 |
RGD:8693672 |
NCBI chr 3:126,554,210...126,578,888
|
|
G |
Rag1 |
recombination activating 1 |
|
IMP |
|
RGD |
PMID:23364523 |
RGD:7207429 |
NCBI chr 3:87,917,061...87,928,158
|
|
G |
Ralbp1 |
ralA binding protein 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23821548 |
|
NCBI chr 9:105,456,425...105,493,235
|
|
G |
Ramp2 |
receptor activity modifying protein 2 |
susceptibility |
ISO IEP |
DNA:SNP:intron associated with Pregnancy Complications mRNA, protein:increased expression:heart myocardium, aorta |
RGD |
PMID:15797661 PMID:11600589 PMID:16450076 |
RGD:1642679, RGD:1642682, RGD:1625300 |
NCBI chr10:86,689,148...86,690,956
|
|
G |
Rasgrp3 |
RAS guanyl releasing protein 3 |
|
ISO |
|
RGD |
PMID:19421330 |
RGD:2314812 |
NCBI chr 6:25,647,386...25,745,952
|
|
G |
Rbfox2 |
RNA binding fox-1 homolog 2 |
|
IEP |
mRNA, protein:splice variant, increased expression:mesenteric artery (rat) |
RGD |
PMID:28993448 |
RGD:329848961 |
NCBI chr 7:108,810,627...109,054,420
|
|
G |
Rbp4 |
retinol binding protein 4 |
sexual_dimorphism ameliorates |
ISO IEP |
protein:increased expression:blood serum (human) |
RGD |
PMID:20798476 PMID:21365528 PMID:25911613 |
RGD:329845596, RGD:329853304, RGD:329845871 |
NCBI chr 1:235,893,917...235,901,315
|
|
G |
Reg3g |
regenerating family member 3 gamma |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27798352 |
|
NCBI chr 4:110,922,805...110,927,803
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
|
IEP ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:19018797 PMID:27659729 PMID:32147540 PMID:16840655 |
RGD:2298761 |
NCBI chr 1:212,354,336...212,364,815
|
|
G |
Ren |
renin |
treatment |
IDA IEP ISO |
CTD Direct Evidence: marker/mechanism protein:decreased activity:plasma (mouse) |
CTD RGD |
PMID:45830 PMID:62162 PMID:998518 PMID:1071603 PMID:1149188 PMID:6381767 PMID:7721401 PMID:11501062 PMID:12414515 PMID:12600921 PMID:17537837 PMID:18679781 PMID:18847324 PMID:19770776 PMID:19934029 PMID:20429690 PMID:20811386 PMID:21393355 PMID:16467505 PMID:30127255 PMID:22493079 PMID:22681982 PMID:16138564 More...
|
RGD:1580671, RGD:401793709, RGD:6892655, RGD:6784501, RGD:1580697 |
NCBI chr13:47,348,312...47,359,539
|
|
G |
Resp18 |
regulated endocrine-specific protein 18 |
|
IMP |
|
RGD |
PMID:29570433 |
RGD:14348960 |
NCBI chr 9:76,765,179...76,771,824
|
|
G |
Resp18em2Mcwi |
regulated endocrine-specific protein 18; zinc finger nuclease induced mutant 2, Medical College of Wisconsin |
|
IMP |
|
RGD |
PMID:29570433 |
RGD:14348960 |
|
|
G |
Retn |
resistin |
|
ISO |
DNA:SNP:3' utr:*62A>G (human) |
RGD |
PMID:12629116 |
RGD:1624968 |
NCBI chr12:6,508,653...6,511,115
|
|
G |
Rffl |
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase |
|
IEP |
mRNA,protein:increased expression:heart |
RGD |
PMID:21357277 |
RGD:13442502 |
NCBI chr10:68,238,273...68,301,225
|
|
G |
Rgs2 |
regulator of G-protein signaling 2 |
|
ISO IEP |
CTD Direct Evidence: therapeutic |
CTD RGD |
PMID:1798635 PMID:14608379 PMID:17986358 |
RGD:13524579, RGD:2289116 |
NCBI chr13:58,350,063...58,352,666
|
|
G |
Rgs4 |
regulator of G-protein signaling 4 |
treatment |
IEP |
|
RGD |
PMID:21825230 |
RGD:7207400 |
NCBI chr13:81,936,775...81,943,103
|
|
G |
Rgs5 |
regulator of G-protein signaling 5 |
treatment |
ISO IEP |
CTD Direct Evidence: therapeutic |
CTD RGD |
PMID:1798635 PMID:21825230 |
RGD:7207400 |
NCBI chr13:81,848,254...81,885,053
|
|
G |
Rhoa |
ras homolog family member A |
|
IEP |
protein:altered localization:mesenteric artery |
RGD |
PMID:17620967 |
RGD:1642801 |
NCBI chr 8:117,870,548...117,904,303
|
|
G |
Rnls |
renalase, FAD-dependent amine oxidase |
|
ISO |
associated with Diabetes Mellitus Type 2; DNA:SNPs: : rs2296545,rs2576178 (human) associated with kidney Failure,Chronic;DNA:SNPs: : rs2576178, rs10887800 (human) |
RGD |
PMID:21964580 PMID:21178975 PMID:21617193 |
RGD:7327172, RGD:7327174, RGD:7327173 |
NCBI chr 1:231,037,481...231,309,855
|
|
G |
Rnpep |
arginyl aminopeptidase |
|
IEP IMP |
protein:increased expression:adrenal gland, neurohypophysis |
RGD |
PMID:9660082 PMID:3001599 |
RGD:2325942, RGD:2325950 |
NCBI chr13:46,699,458...46,717,829
|
|
G |
Rps6kb1 |
ribosomal protein S6 kinase B1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19289642 |
|
NCBI chr10:71,817,794...71,865,211
|
|
G |
RT1-Ba |
RT1 class II, locus Ba |
|
ISO |
DNA:polymorphisms (human) |
RGD |
PMID:11798899 |
RGD:5147807 |
NCBI chr20:4,575,134...4,579,727
|
|
G |
S100b |
S100 calcium binding protein B |
|
ISO |
protein:increased expression:serum |
RGD |
PMID:21130083 |
RGD:5508770 |
NCBI chr20:12,372,345...12,381,159
|
|
G |
S1pr1 |
sphingosine-1-phosphate receptor 1 |
disease_progression |
IAGP |
associated with SHRSP;mRNA,protein:increased expression, decreased expression:kidney (rat) |
RGD |
PMID:17938382 |
RGD:1643008 |
NCBI chr 2:206,309,715...206,314,070
|
|
G |
Scnn1a |
sodium channel epithelial 1 subunit alpha |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:11752024 PMID:23348737 |
|
NCBI chr 4:158,122,962...158,146,184
|
|
G |
Scnn1b |
sodium channel epithelial 1 subunit beta |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15174897 PMID:15198480 PMID:19344079 |
|
NCBI chr 1:185,861,326...185,915,717
|
|
G |
Scnn1g |
sodium channel epithelial 1 subunit gamma |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15198480 |
|
NCBI chr 1:185,736,225...185,770,099
|
|
G |
Selp |
selectin P |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15513305 |
|
NCBI chr13:76,476,229...76,511,846
|
|
G |
Serpina1 |
serpin family A member 1 |
|
ISO |
protein:increased expression:urine |
RGD |
PMID:10353322 |
RGD:1643147 |
NCBI chr 6:128,631,101...128,653,125
|
|
G |
Serpine1 |
serpin family E member 1 |
treatment |
ISO IEP IDA |
protein:increased expression:plasma (human) mRNA:increased expression:kidney (SHRSP/A3N rat) CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:21051829 PMID:22352330 PMID:8355419 PMID:11907153 PMID:16645728 |
RGD:8547753, RGD:28912746, RGD:11081003 |
NCBI chr12:25,237,977...25,248,356
|
|
G |
Serpine2 |
serpin family E member 2 |
|
IEP |
mRNA, protein:increased expression:blood vessel |
RGD |
PMID:12524238 |
RGD:729767 |
NCBI chr 9:81,124,746...81,188,866
|
|
G |
Serpinf2 |
serpin family F member 2 |
|
ISO |
|
RGD |
PMID:9361364 |
RGD:1625531 |
NCBI chr10:60,272,400...60,280,506
|
|
G |
Sgk1 |
serum/glucocorticoid regulated kinase 1 |
no_association susceptibility |
ISO |
DNA:snps:exon, intron: (human) |
RGD |
PMID:15304560 PMID:16221215 |
RGD:1580969, RGD:1580968 |
NCBI chr 1:24,799,391...24,916,886
|
|
G |
Sh2b3 |
SH2B adaptor protein 3 |
|
IMP |
|
RGD |
PMID:25776069 |
RGD:13442483 |
NCBI chr12:34,731,934...34,753,617
|
|
G |
Sh2b3em1Mcwi |
SH2B adaptor protein 3; zinc finger nuclease induced mutant 1, Medical College of Wisconsin |
|
IMP |
|
RGD |
PMID:25776069 |
RGD:13442483 |
|
|
G |
Sirt6 |
sirtuin 6 |
exacerbates |
ISO |
|
RGD |
PMID:30894089 |
RGD:155260334 |
NCBI chr 7:8,082,312...8,087,776
|
|
G |
Slc12a2 |
solute carrier family 12 member 2 |
|
IEP ISO IDA |
mRNA:increased expression:aorta CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:17259435 PMID:15020309 PMID:21814290 |
RGD:1580582, RGD:9587757 |
NCBI chr18:51,348,282...51,416,448
|
|
G |
Slc12a3 |
solute carrier family 12 member 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18480177 |
|
NCBI chr19:10,636,594...10,690,008
|
|
G |
Slc26a4 |
solute carrier family 26 member 4 |
|
ISO |
|
RGD |
PMID:17120771 |
RGD:7411553 |
NCBI chr 6:53,835,102...53,873,968
|
|
G |
Slc2a1 |
solute carrier family 2 member 1 |
|
IEP |
protein:increased expression:renal glomerulus |
RGD |
PMID:12771048 |
RGD:12879474 |
NCBI chr 5:138,002,522...138,030,742
|
|
G |
Slc2a3 |
solute carrier family 2 member 3 |
|
IEP |
protein:decreased expression:hippocampus, parietal cortex; protein:increased expression:hypothalamus, thalamus |
RGD |
PMID:7598707 |
RGD:1642812 |
NCBI chr 4:157,632,887...157,698,034
|
|
G |
Slc4a4 |
solute carrier family 4 member 4 |
|
IEP |
protein:increased expression:kidney cortex |
RGD |
PMID:15340004 |
RGD:1600028 |
NCBI chr14:19,125,394...19,577,379
|
|
G |
Slc5a2 |
solute carrier family 5 member 2 |
|
IDA |
|
RGD |
PMID:14506074 |
RGD:1599050 |
NCBI chr 1:192,277,621...192,283,742
|
|
G |
Slc6a18 |
solute carrier family 6 member 18 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15121838 |
|
NCBI chr 1:29,607,288...29,621,925
|
|
G |
Slc6a19 |
solute carrier family 6 member 19 |
|
IEP |
mRNA:increased expression |
RGD |
PMID:17264310 |
RGD:1600036 |
NCBI chr 1:29,586,191...29,604,964
|
|
G |
Slc6a2 |
solute carrier family 6 member 2 |
|
ISO |
DNA:polymorphism:1287G>A CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:22533655 PMID:17124432 |
RGD:1624279 |
NCBI chr19:30,183,289...30,228,292
|
|
G |
Slc6a3 |
solute carrier family 6 member 3 |
|
IEP |
protein:increased expression:caudate-putamen |
RGD |
PMID:9074541 |
RGD:1625656 |
NCBI chr 1:31,537,990...31,578,962
|
|
G |
Slc8a1 |
solute carrier family 8 member A1 |
|
IEP ISO |
DNA:snps:intron:g.-23200T>C, g.-23181T>C (human) DNA:SNP: :1784C>T |
RGD |
PMID:16343576 PMID:15785003 PMID:15824464 |
RGD:1598724, RGD:1580732, RGD:1580586 |
NCBI chr 6:13,194,609...13,547,369
|
|
G |
Slc9a3 |
solute carrier family 9 member A3 |
|
IDA |
|
RGD |
PMID:11880335 PMID:12372791 |
RGD:737665, RGD:727447 |
NCBI chr 1:29,124,633...29,167,912
|
|
G |
Sod1 |
superoxide dismutase 1 |
treatment |
ISO IEP |
associated with Hydronephrosis CTD Direct Evidence: marker/mechanism|therapeutic human gene in a rat model mRNA:decreased expression:rostral ventrolateral medulla (rat) |
CTD RGD |
PMID:9024144 PMID:25101153 PMID:32165127 PMID:19403858 PMID:31572179 PMID:16716903 PMID:16864745 PMID:16716903 PMID:17198913 More...
|
RGD:2312366, RGD:329956417, RGD:1580833, RGD:1581232, RGD:1580833, RGD:1600704 |
NCBI chr11:42,942,742...42,948,399
|
|
G |
Sod2 |
superoxide dismutase 2 |
|
IDA ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:11834524 PMID:21593737 PMID:25101153 PMID:16716903 |
RGD:1580833 |
NCBI chr 1:50,043,323...50,050,168
|
|
G |
Sod3 |
superoxide dismutase 3 |
|
IDA ISO |
CTD Direct Evidence: marker/mechanism|therapeutic |
CTD RGD |
PMID:16864745 PMID:17023265 PMID:12600899 PMID:16864745 |
RGD:1580845, RGD:1581232 |
NCBI chr14:62,822,865...62,828,602
|
|
G |
Sqstm1 |
sequestosome 1 |
|
IEP |
protein:decreased expression:brain |
RGD |
PMID:23499735 |
RGD:11561939 |
NCBI chr10:35,026,598...35,037,750
|
|
G |
Src |
SRC proto-oncogene, non-receptor tyrosine kinase |
|
IDA |
|
RGD |
PMID:16157790 |
RGD:1601372 |
NCBI chr 3:166,511,616...166,559,463
|
|
G |
Srf |
serum response factor |
|
IDA |
|
RGD |
PMID:16822834 |
RGD:1580749 |
NCBI chr 9:21,924,050...21,933,338
|
|
G |
Sst |
somatostatin |
|
IEP |
protein:altered expression:stomach |
RGD |
PMID:17928643 |
RGD:2303191 |
NCBI chr11:76,956,896...76,958,173
|
|
G |
Stim1 |
stromal interaction molecule 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19897708 |
|
NCBI chr 1:156,656,246...156,818,777
|
|
G |
Stk11 |
serine/threonine kinase 11 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19289642 |
|
NCBI chr 7:10,225,204...10,241,965
|
|
G |
Stk39 |
serine threonine kinase 39 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:22949526 |
|
NCBI chr 3:73,321,522...73,588,397
|
|
G |
Sts |
steroid sulfatase |
|
IEP |
protein:increased expression:multiple organs |
RGD |
PMID:8539776 |
RGD:1601393 |
NCBI chr X:46,102,524...46,110,868
|
|
G |
Tac3 |
tachykinin precursor 3 |
|
IEP |
protein:increased expression:supraoptic nucleus, medulla oblongata |
RGD |
PMID:2478257 |
RGD:2305983 |
NCBI chr 7:63,562,552...63,569,170
|
|
G |
Tacr1 |
tachykinin receptor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21294877 |
|
NCBI chr 4:116,478,617...116,647,492
|
|
G |
Tacr3 |
tachykinin receptor 3 |
|
IDA |
|
RGD |
PMID:2471579 |
RGD:2305984 |
NCBI chr 2:223,266,536...223,363,791
|
|
G |
Tbxas1 |
thromboxane A synthase 1 |
|
IDA |
associated with hyperinsulinism |
RGD |
PMID:9370383 PMID:16192456 |
RGD:1601472, RGD:1601439 |
NCBI chr 4:67,664,963...67,837,096
|
|
G |
Tf |
transferrin |
|
ISO |
protein:decreased expression |
RGD |
PMID:14974364 |
RGD:1601524 |
NCBI chr 8:103,789,780...103,816,487
|
|
G |
Tgfb1 |
transforming growth factor, beta 1 |
|
IEP ISO IAGP |
protein:increased expression:vascular associated smooth muscle cell protein:increased expression:blood serum (human) mRNA:increased expression:kidney (SHRSP/A3N rat) protein:increased expression:renal glomerulus CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:11682445 PMID:19018797 PMID:17364610 PMID:26502942 PMID:11907153 PMID:11682445 PMID:12771048 PMID:15118671 More...
|
RGD:1601552, RGD:329955577, RGD:28912746, RGD:30296650, RGD:12879474, RGD:1331525 |
NCBI chr 1:90,324,312...90,340,627
|
|
G |
Tgfb3 |
transforming growth factor, beta 3 |
no_association |
ISO |
DNA:polymorphism, SNPs |
RGD |
PMID:15924806 |
RGD:1625704 |
NCBI chr 6:111,435,170...111,457,646
|
|
G |
Tgm2 |
transglutaminase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17898543 |
|
NCBI chr 3:167,192,612...167,221,845
|
|
G |
Th |
tyrosine hydroxylase |
susceptibility |
IEP ISO |
mRNA:increased expression:brain CTD Direct Evidence: marker/mechanism DNA:polymorphism:intron:g.1090T>C rs2070762 (human) |
CTD RGD |
PMID:27659729 PMID:32147540 PMID:32165127 PMID:16650497 PMID:16636198 |
RGD:1601630, RGD:1601631 |
NCBI chr 1:207,500,959...207,508,276
|
|
G |
Thbd |
thrombomodulin |
treatment |
IEP ISO |
associated with Experimental Diabetes Mellitus protein:increased expression:plasma protein:decreased expression:plasma |
RGD |
PMID:14737039 PMID:16095049 PMID:17401180 PMID:12611420 |
RGD:1601646, RGD:5685017, RGD:1601636, RGD:1601652 |
NCBI chr 3:156,316,526...156,320,178
|
|
G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
|
ISO IEP |
protein:decreased expression:glomerulus CTD Direct Evidence: marker/mechanism mRNA, protein:increased expression:kidney |
CTD RGD |
PMID:21051829 PMID:19506087 PMID:17977875 |
RGD:2312464, RGD:2290351 |
NCBI chr X:3,766,509...3,772,578
|
|
G |
Tjp2 |
tight junction protein 2 |
|
IEP |
protein:decreased expression:brain |
RGD |
PMID:17234953 |
RGD:1600163 |
NCBI chr 1:221,709,745...221,838,291
|
|
G |
Tlr4 |
toll-like receptor 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27292124 PMID:32147540 |
|
NCBI chr 5:85,161,247...85,174,882
|
|
G |
Tnf |
tumor necrosis factor |
ameliorates treatment |
IAGP IEP ISO IMP |
associated with Cardiac Fibrosis CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:18605955 PMID:27292124 PMID:27659729 PMID:27847271 PMID:32147540 PMID:9590569 PMID:25715999 PMID:16415373 More...
|
RGD:1357163, RGD:401794570, RGD:1580207 |
NCBI chr20:3,626,685...3,629,303
|
|
G |
Tnfrsf11b |
TNF receptor superfamily member 11B |
severity |
ISO |
protein:increased expression:serum |
RGD |
PMID:22050177 |
RGD:7205512 |
NCBI chr 7:87,456,318...87,484,324
|
|
G |
Tp53 |
tumor protein p53 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22228705 |
|
NCBI chr10:54,798,871...54,810,300
|
|
G |
Tpm1 |
tropomyosin 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22228705 |
|
NCBI chr 8:67,635,479...67,662,330
|
|
G |
Trh |
thyrotropin releasing hormone |
|
IDA ISO |
protein:decreased expression:diencephalon CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:6350720 PMID:17227965 |
RGD:1600406 |
NCBI chr 4:124,742,111...124,777,094
|
|
G |
Trhr |
thyrotropin releasing hormone receptor |
|
IDA |
|
RGD |
PMID:7554113 |
RGD:1580745 |
NCBI chr 7:75,348,672...75,393,310
|
|
G |
Trpc3 |
transient receptor potential cation channel, subfamily C, member 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17351372 |
|
NCBI chr 2:119,481,313...119,619,333
|
|
G |
Trpc5 |
transient receptor potential cation channel, subfamily C, member 5 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17351372 |
|
NCBI chr X:107,946,163...108,230,991
|
|
G |
Ucn |
urocortin |
|
ISO |
associated with Pregnancy Complications;protein:increased expression:plasma CTD Direct Evidence: therapeutic |
CTD RGD |
PMID:20237592 PMID:16915033 |
RGD:1642775 |
NCBI chr 6:30,958,086...30,958,916
|
|
G |
Ucn2 |
urocortin 2 |
|
ISO |
human protein in rat model |
RGD |
PMID:19204182 |
RGD:5508437 |
NCBI chr 8:118,516,111...118,517,660
|
|
G |
Ucp1 |
uncoupling protein 1 |
|
ISO |
DNA:polymorphism: :-3826A>G (human) |
RGD |
PMID:17635070 |
RGD:2313626 |
NCBI chr19:41,713,350...41,721,421
|
|
G |
Ucp2 |
uncoupling protein 2 |
treatment |
ISO IDA |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:16685210 PMID:15106800 PMID:20404217 |
RGD:1580794, RGD:7175297 |
NCBI chr 1:164,251,373...164,257,742
|
|
G |
Ucp3 |
uncoupling protein 3 |
|
IEP |
|
RGD |
PMID:10994754 |
RGD:1580795 |
NCBI chr 1:154,815,777...154,828,764
|
|
G |
Ugcg |
UDP-glucose ceramide glucosyltransferase |
treatment |
IEP |
|
RGD |
PMID:23528973 |
RGD:401793732 |
NCBI chr 5:78,828,006...78,860,725
|
|
G |
Umod |
uromodulin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22228705 |
|
NCBI chr 1:183,247,676...183,261,665
|
|
G |
Uts2 |
urotensin 2 |
|
ISO IDA |
protein:increased expression:plasma CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:16160878 PMID:15201550 PMID:14621188 |
RGD:1580808, RGD:1580812 |
NCBI chr 5:161,450,846...161,456,235
|
|
G |
Uts2r |
urotensin 2 receptor |
|
IDA |
|
RGD |
PMID:14621188 |
RGD:1580812 |
NCBI chr10:106,438,092...106,439,252
|
|
G |
Vav3 |
vav guanine nucleotide exchange factor 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21115475 |
|
NCBI chr 2:199,699,861...200,042,344
|
|
G |
Vcam1 |
vascular cell adhesion molecule 1 |
disease_progression |
IEP IAGP ISO |
mRNA:increased expression:multiple organs associated with SHRSP;mRNA,protein:increased expression:kidney, membrane fraction (rat) CTD Direct Evidence: marker/mechanism associated with Diabetes Mellitus, Type1; protein:increased expression:serum: |
CTD RGD |
PMID:11834524 PMID:19018797 PMID:19080338 PMID:17938382 PMID:20569722 |
RGD:2313107, RGD:1643008, RGD:7241235 |
NCBI chr 2:206,723,050...206,742,783
|
|
G |
Vdr |
vitamin D receptor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:11335187 |
|
NCBI chr 7:130,864,764...130,916,757
|
|
G |
Vegfa |
vascular endothelial growth factor A |
treatment |
ISO |
associated with Prostatic Neoplasms |
RGD |
PMID:16164572 PMID:20630084 |
RGD:1580573, RGD:8552374 |
NCBI chr 9:22,452,854...22,468,194
|
|
G |
Vhl |
von Hippel-Lindau tumor suppressor |
|
ISO |
|
RGD |
PMID:12500216 |
RGD:1580371 |
NCBI chr 4:146,772,483...146,779,376
|
|
G |
Vwf |
von Willebrand factor |
treatment |
ISO IEP |
CTD Direct Evidence: marker/mechanism associated with Experimental Diabetes Mellitus |
CTD RGD |
PMID:12149661 PMID:12425201 PMID:22352330 PMID:14737039 |
RGD:1601646 |
NCBI chr 4:160,042,900...160,177,757
|
|
G |
Wnk1 |
WNK lysine deficient protein kinase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:22949526 PMID:16301342 |
RGD:1580829 |
NCBI chr 4:154,800,590...154,926,147
|
|
G |
Wnk4 |
WNK lysine deficient protein kinase 4 |
no_association |
IAGP ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:22949526 PMID:12642508 PMID:15110905 |
RGD:629611, RGD:1580830 |
NCBI chr10:86,702,828...86,719,917
|
|
G |
Xdh |
xanthine dehydrogenase |
treatment |
IDA IEP ISO |
DNA:SNPs:exon, intron:47686C>T, 69901A>C, 67873A>C (p.N1109T) (human) |
RGD |
PMID:23746952 PMID:12826072 PMID:18712049 PMID:18728266 |
RGD:7247630, RGD:13210518, RGD:7247654, RGD:7247653 |
NCBI chr 6:21,530,463...21,592,172
|
|
G |
Xrcc1 |
X-ray repair cross complementing 1 |
susceptibility |
ISO |
DNA:SNP,haplotypes: p.R194W, p.R399Q (rs1799782, rs25487) (human) |
RGD |
PMID:25529925 |
RGD:401827819 |
NCBI chr 1:89,268,721...89,296,619
|
|
G |
Xrcc3 |
X-ray repair cross complementing 3 |
susceptibility |
ISO |
DNA:SNP,haplotype:cd: p.T241M (rs861539) (human) |
RGD |
PMID:25529925 |
RGD:401827819 |
NCBI chr 6:136,684,558...136,694,822
|
|
G |
Ywhaz |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta |
treatment |
IEP |
|
RGD |
PMID:22984478 |
RGD:9587480 |
NCBI chr 7:69,826,404...69,848,702
|
|
|
G |
Map3k7 |
mitogen activated protein kinase kinase kinase 7 |
|
ISO |
protein:increased expression:cortex of kidney (human) |
RGD |
PMID:34584221 |
RGD:155791449 |
NCBI chr 5:51,149,524...51,212,012
|
|
|
G |
Kcnip1 |
potassium voltage-gated channel interacting protein 1 |
|
ISO |
ClinVar Annotator: match by term: KCNMB1-related condition |
ClinVar |
PMID:15057310 PMID:16155733 |
|
NCBI chr10:18,219,519...18,588,833
|
|
G |
Kcnmb1 |
potassium calcium-activated channel subfamily M regulatory beta subunit 1 |
|
ISO |
ClinVar Annotator: match by term: KCNMB1-related condition CTD Direct Evidence: marker/mechanism |
OMIM ClinVar CTD |
PMID:15057310 PMID:16155733 |
|
NCBI chr10:19,062,014...19,119,005
|
|
|
G |
G6pc3 |
glucose 6 phosphatase catalytic subunit 3 |
|
ISO |
ClinVar Annotator: match by term: Dursun syndrome |
ClinVar |
PMID:25741868 PMID:28492532 |
|
NCBI chr10:87,146,987...87,151,223
|
|
|
G |
Il6 |
interleukin 6 |
treatment |
IDA |
|
RGD |
PMID:27106269 |
RGD:11062145 |
NCBI chr 4:5,889,999...5,894,575
|
|
|
G |
Acsm3 |
acyl-CoA synthetase medium-chain family member 3 |
no_association |
ISO |
|
RGD |
PMID:11592044 |
RGD:1579978 |
NCBI chr 1:174,133,260...174,159,966
|
|
G |
Add1 |
adducin 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism ClinVar Annotator: match by term: Hypertension, salt-sensitive essential, susceptibility to |
OMIM CTD ClinVar |
PMID:9149697 PMID:9607177 PMID:10024330 PMID:10523341 PMID:11882573 PMID:12623934 PMID:14553962 PMID:18591455 PMID:19057513 PMID:22992668 PMID:23863317 More...
|
|
NCBI chr14:76,108,643...76,167,267
|
|
G |
Agt |
angiotensinogen |
|
ISO |
ClinVar Annotator: match by term: AGT-related condition | ClinVar Annotator: match by term: Essential hypertension, genetic | ClinVar Annotator: match by term: Hypertension, essential, susceptibility to CTD Direct Evidence: marker/mechanism |
ClinVar CTD |
PMID:1394429 PMID:7649545 PMID:7883995 PMID:8348146 PMID:8513325 PMID:8518804 PMID:9120024 PMID:9259580 PMID:9421481 PMID:9831339 PMID:9894356 PMID:12743009 PMID:13937884 PMID:15077204 PMID:16059745 PMID:17047091 PMID:20978123 PMID:24452034 PMID:25278896 PMID:25741868 PMID:28492532 PMID:35005812 More...
|
|
NCBI chr19:69,426,540...69,447,017
|
|
G |
Agtr1a |
angiotensin II receptor, type 1a |
treatment |
ISO |
ClinVar Annotator: match by term: Essential hypertension | ClinVar Annotator: match by term: Essential hypertension, genetic | ClinVar Annotator: match by term: Hypertension, essential, susceptibility to CTD Direct Evidence: marker/mechanism |
OMIM ClinVar CTD RGD |
PMID:8021009 PMID:9084931 PMID:15042429 PMID:16116425 PMID:25741868 PMID:28492532 PMID:28973083 PMID:18604484 More...
|
RGD:10047396 |
NCBI chr17:34,383,397...34,435,523
|
|
G |
Aif1 |
allograft inflammatory factor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34453990 |
|
NCBI chr20:3,651,435...3,657,341
|
|
G |
Atp1b1 |
ATPase Na+/K+ transporting subunit beta 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
OMIM CTD |
|
|
NCBI chr13:76,786,580...76,807,096
|
|
G |
Atp2a2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
susceptibility |
ISO |
DNA:polymorphism:exon:p.A724A (c.2171G>A)(human) |
RGD |
PMID:20687374 |
RGD:13507310 |
NCBI chr12:34,072,710...34,122,142
|
|
G |
Atp5pf |
ATP synthase peripheral stalk subunit F6 |
|
ISO |
protein:increased expression:plasma (human) |
RGD |
PMID:14654753 |
RGD:13800915 |
NCBI chr11:37,368,045...37,375,721
|
|
G |
Caly |
calcyon neuron-specific vesicular protein |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30753204 |
|
NCBI chr 1:194,862,671...194,873,861
|
|
G |
Cat |
catalase |
|
ISO |
|
RGD |
PMID:15735318 |
RGD:1581147 |
NCBI chr 3:110,297,340...110,329,526
|
|
G |
Cdca3 |
cell division cycle associated 3 |
|
ISO |
ClinVar Annotator: match by term: Hypertension, essential, susceptibility to |
ClinVar |
PMID:9425898 PMID:10477144 PMID:10523525 PMID:10770297 PMID:10770309 PMID:10770310 PMID:11322952 PMID:12668921 PMID:25741868 PMID:28492532 More...
|
|
NCBI chr 4:159,321,203...159,325,072
|
|
G |
Cyba |
cytochrome b-245 alpha chain |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34453990 |
|
NCBI chr19:50,487,598...50,495,669
|
|
G |
Cybb |
cytochrome b-245 beta chain |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34453990 |
|
NCBI chr X:16,030,596...16,065,065
|
|
G |
Cyp3a9 |
cytochrome P450, family 3, subfamily a, polypeptide 9 |
susceptibility |
ISO |
ClinVar Annotator: match by term: CYP3A5-related condition | ClinVar Annotator: match by term: Hypertension, salt-sensitive essential, susceptibility to CTD Direct Evidence: marker/mechanism |
ClinVar CTD OMIM |
PMID:11279519 PMID:11740341 PMID:12065767 PMID:12754175 PMID:15492926 |
|
NCBI chr12:21,919,955...21,960,160
|
|
G |
Ece1 |
endothelin converting enzyme 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism ClinVar Annotator: match by term: ECE1-related condition |
CTD OMIM ClinVar |
PMID:25741868 PMID:28492532 |
|
NCBI chr 5:155,361,031...155,462,723
|
|
G |
Eln |
elastin |
|
ISS |
OMIM:145500 | OMIM:603918 | OMIM:604329 | OMIM:607329 | OMIM:608742 | OMIM:610261 | OMIM:610262 | OMIM:610948 | OMIM:611014 |
MouseDO |
|
|
NCBI chr12:27,604,983...27,648,413
|
|
G |
Ffar2 |
free fatty acid receptor 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34453990 |
|
NCBI chr 1:95,199,277...95,202,599
|
|
G |
Ffar3 |
free fatty acid receptor 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34453990 |
|
NCBI chr 1:95,232,804...95,234,144
|
|
G |
Fgfr2 |
fibroblast growth factor receptor 2 |
sexual_dimorphism |
IEP |
mRNA, protein:decreased expression:inferior vagus X ganglion, nucleus of solitary tract (rat) |
RGD |
PMID:31626954 |
RGD:155791444 |
NCBI chr 1:194,175,703...194,280,914
|
|
G |
Fto |
FTO, alpha-ketoglutarate dependent dioxygenase |
|
ISO |
DNA:SNP: :rs8050136 (human) |
RGD |
PMID:23691120 |
RGD:329845889 |
NCBI chr19:31,456,749...31,865,011
|
|
G |
Gata5 |
GATA binding protein 5 |
|
ISS ISO |
OMIM:145500 | OMIM:603918 | OMIM:604329 | OMIM:607329 | OMIM:608742 | OMIM:610261 | OMIM:610262 | OMIM:610948 | OMIM:611014 |
MouseDO RGD |
PMID:26617239 |
RGD:11343485 |
NCBI chr 3:187,796,140...187,804,327
|
|
G |
Gnb3 |
G protein subunit beta 3 |
susceptibility |
ISO |
ClinVar Annotator: match by term: Hypertension, essential, susceptibility to CTD Direct Evidence: marker/mechanism DNA:SNP: :rs5443, rs1129649 (human) |
ClinVar OMIM CTD RGD |
PMID:9425898 PMID:10477144 PMID:10523525 PMID:10770297 PMID:10770309 PMID:10770310 PMID:11322952 PMID:12668921 PMID:25741868 PMID:28492532 PMID:23691120 More...
|
RGD:329845889 |
NCBI chr 4:157,639,468...157,645,171
|
|
G |
Grk4 |
G protein-coupled receptor kinase 4 |
susceptibility |
ISO |
DNA:SNP,haplotypes:cds: |
RGD |
PMID:15097232 PMID:15097232 |
RGD:1598505, RGD:1598505 |
NCBI chr14:80,230,699...80,305,292
|
|
G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
|
ISO |
protein:increased expression:urine: |
RGD |
PMID:22923545 |
RGD:7245500 |
NCBI chr10:31,118,667...31,151,730
|
|
G |
Hmgb1 |
high mobility group box 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34453990 |
|
NCBI chr12:11,009,236...11,015,941
|
|
G |
Hsd11b1 |
hydroxysteroid 11-beta dehydrogenase 1 |
susceptibility |
ISO |
DNA:SNP:insertion: ins4436A (rs45487298) (human) |
RGD |
PMID:26671915 |
RGD:11353457 |
NCBI chr13:104,728,539...104,798,884
|
|
G |
Il1b |
interleukin 1 beta |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34453990 |
|
NCBI chr 3:137,030,200...137,036,581
|
|
G |
Lcn2 |
lipocalin 2 |
|
ISO |
protein:increased expression:urine: |
RGD |
PMID:22923545 |
RGD:7245500 |
NCBI chr 3:36,078,432...36,081,851
|
|
G |
Mir126a |
microRNA 126a |
|
ISO |
RNA:decreased expression:peripheral blood mononuclear cell |
RGD |
PMID:24794206 |
RGD:401851039 |
NCBI chr 3:29,813,150...29,813,267
|
|
G |
Ncf1 |
neutrophil cytosolic factor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34453990 |
|
NCBI chr12:28,121,816...28,131,080
|
|
G |
Nos3 |
nitric oxide synthase 3 |
|
ISO ISS |
DNA:repeats:intron:IVS13+?-?dupCA (human) OMIM:145500 | OMIM:603918 | OMIM:604329 | OMIM:607329 | OMIM:608742 | OMIM:610261 | OMIM:610262 | OMIM:610948 | OMIM:611014 CTD Direct Evidence: marker/mechanism ClinVar Annotator: match by term: Essential hypertension DNA:snp:cds:p.E298D (human) |
MouseDO CTD ClinVar RGD |
PMID:25741868 PMID:9084930 PMID:11394896 |
RGD:1580277, RGD:1580280 |
NCBI chr 4:11,686,088...11,706,604
|
|
G |
Nppb |
natriuretic peptide B |
|
ISO |
protein:increased expression:plasma: |
RGD |
PMID:9350073 |
RGD:7246914 |
NCBI chr 5:163,699,955...163,701,314
|
|
G |
Npr2 |
natriuretic peptide receptor 2 |
|
ISO |
DNA:repeat:intron:IVS2+150(GT)10-11 (human) |
RGD |
PMID:10082481 |
RGD:1580772 |
NCBI chr 5:62,678,197...62,697,360
|
|
G |
Ocln |
occludin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34453990 |
|
NCBI chr 2:33,391,303...33,442,207
|
|
G |
Phactr1 |
phosphatase and actin regulator 1 |
susceptibility |
ISO |
DNA:SNP::g.12903725A>G (rs9349379) (human) |
RGD |
PMID:34758666 |
RGD:401900745 |
NCBI chr17:21,560,364...22,040,166
|
|
G |
Ptgis |
prostaglandin I2 synthase |
|
ISO |
CTD Direct Evidence: marker/mechanism ClinVar Annotator: match by term: Essential hypertension | ClinVar Annotator: match by term: Essential hypertension, genetic |
OMIM CTD ClinVar |
PMID:12372404 PMID:25741868 |
|
NCBI chr 3:155,928,564...155,964,228
|
|
G |
Ptpn1 |
protein tyrosine phosphatase, non-receptor type 1 |
susceptibility |
ISO |
DNA:SNPs::g.54281T>A, 15/37C>A (human) |
RGD |
PMID:20101100 |
RGD:401959376 |
NCBI chr 3:156,638,811...156,687,503
|
|
G |
Rarres2 |
retinoic acid receptor responder 2 |
|
ISO |
protein:increased expression:serum: |
RGD |
PMID:24047472 |
RGD:15036820 |
NCBI chr 4:77,522,549...77,525,733
|
|
G |
Rbp4 |
retinol binding protein 4 |
disease_progression |
ISO |
protein:increased expression:blood plasma (human) protein:increased expression:blood serum (human) |
RGD |
PMID:31865725 PMID:19556974 |
RGD:329845583, RGD:329845861 |
NCBI chr 1:235,893,917...235,901,315
|
|
G |
Ren |
renin |
|
ISO |
|
RGD |
PMID:1152295 |
RGD:125097505 |
NCBI chr13:47,348,312...47,359,539
|
|
G |
Rgs5 |
regulator of G-protein signaling 5 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
OMIM CTD |
|
|
NCBI chr13:81,848,254...81,885,053
|
|
G |
Rnls |
renalase, FAD-dependent amine oxidase |
|
ISO |
DNA:SNPs: :rs2576178, rs2296545,rs2114406 (human) |
RGD |
PMID:17216203 |
RGD:7327177 |
NCBI chr 1:231,037,481...231,309,855
|
|
G |
Slc12a3 |
solute carrier family 12 member 3 |
severity |
ISO |
DNA:missense mutation:cds:p.R904Q (human) DNA:snp:intron:g.1784C>T (human) |
RGD |
PMID:15480096 PMID:15824464 |
RGD:1580589, RGD:1580586 |
NCBI chr19:10,636,594...10,690,008
|
|
G |
Th |
tyrosine hydroxylase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34453990 |
|
NCBI chr 1:207,500,959...207,508,276
|
|
G |
Tjp1 |
tight junction protein 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34453990 |
|
NCBI chr 1:128,260,330...128,505,018
|
|
G |
Tlr2 |
toll-like receptor 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34453990 |
|
NCBI chr 2:171,499,189...171,504,831
|
|
G |
Tlr4 |
toll-like receptor 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34453990 |
|
NCBI chr 5:85,161,247...85,174,882
|
|
G |
Tnf |
tumor necrosis factor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34453990 |
|
NCBI chr20:3,626,685...3,629,303
|
|
G |
Umod |
uromodulin |
|
ISO |
ClinVar Annotator: match by term: Essential hypertension |
ClinVar |
|
|
NCBI chr 1:183,247,676...183,261,665
|
|
G |
Zscan25 |
zinc finger and SCAN domain containing 25 |
|
ISO |
ClinVar Annotator: match by term: CYP3A5-related condition | ClinVar Annotator: match by term: Hypertension, salt-sensitive essential, susceptibility to |
ClinVar |
PMID:11279519 PMID:11740341 PMID:12065767 PMID:12754175 PMID:15492926 |
|
NCBI chr12:9,327,347...9,338,206
|
|
|
G |
Dap3 |
death associated protein 3 |
|
ISO |
ClinVar Annotator: match by term: Grange syndrome | ClinVar Annotator: match by term: YY1AP1-related condition |
ClinVar |
PMID:25741868 PMID:28492532 |
|
NCBI chr 2:174,319,341...174,347,489
|
|
|
G |
Adamts13 |
ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
|
ISO |
protein:decreased activity:plasma (human) |
RGD |
PMID:12969811 |
RGD:10449045 |
NCBI chr 3:10,299,264...10,338,464
|
|
G |
Ahsp |
alpha hemoglobin stabilizing protein |
|
ISO |
mRNA:decreased expression:placenta (human) |
RGD |
PMID:18347943 |
RGD:329956422 |
NCBI chr 1:182,879,901...182,885,508
|
|
G |
Cd40lg |
CD40 ligand |
|
ISO |
protein:increased expression:blood platelet (human) |
RGD |
PMID:23241952 |
RGD:11522719 |
NCBI chr X:140,164,341...140,176,057
|
|
G |
Erbb2 |
erb-b2 receptor tyrosine kinase 2 |
|
ISO |
|
RGD |
PMID:9158311 |
RGD:1580990 |
NCBI chr10:83,907,491...83,931,365
|
|
G |
Fas |
Fas cell surface death receptor |
susceptibility |
ISO IEP |
DNA:SNP:promoter:-670A>G(rs1800682)(human) protein,mRNA:altered expression:placenta, liver: |
RGD |
PMID:30066360 PMID:28501275 |
RGD:14700669, RGD:14700673 |
NCBI chr 1:241,212,155...241,245,774
|
|
G |
Faslg |
Fas ligand |
susceptibility |
ISO IEP |
DNA:SNP:intron:124A>G(rs5030772)(human) protein:altered expression:blood, placenta, liver: |
RGD |
PMID:30066360 PMID:28501275 |
RGD:14700669, RGD:14700673 |
NCBI chr13:76,680,885...76,706,042
|
|
|
G |
Sars1 |
seryl-tRNA synthetase 1 |
|
ISO |
ClinVar Annotator: match by term: HYPERURICEMIA, PULMONARY HYPERTENSION, RENAL FAILURE, AND ALKALOSIS SYNDROME |
ClinVar |
PMID:25741868 PMID:28492532 |
|
NCBI chr 2:198,753,673...198,769,411
|
|
G |
Sars2 |
seryl-tRNA synthetase 2, mitochondrial |
|
ISO |
ClinVar Annotator: match by term: HYPERURICEMIA, PULMONARY HYPERTENSION, RENAL FAILURE, AND ALKALOSIS SYNDROME | ClinVar Annotator: match by term: Hyperuricemia, pulmonary hypertension, renal failure, and alkalosis | ClinVar Annotator: match by term: SARS2-related condition DNA:missense mutation:CDS:p.D390G (human) |
OMIM ClinVar RGD |
PMID:9536098 PMID:17576681 PMID:21255763 PMID:24034276 PMID:25741868 PMID:27279129 PMID:28492532 PMID:31607746 PMID:33751860 PMID:21255763 More...
|
RGD:41410777 |
NCBI chr 1:84,028,972...84,040,725
|
|
|
G |
Pde3a |
phosphodiesterase 3A |
|
ISO |
ClinVar Annotator: match by term: Bilginturan syndrome | ClinVar Annotator: match by term: PDE3A-related condition CTD Direct Evidence: marker/mechanism |
OMIM ClinVar CTD |
PMID:4774535 PMID:25741868 PMID:25961942 PMID:28492532 PMID:29758562 PMID:31549136 PMID:32631253 More...
|
|
NCBI chr 4:174,172,804...174,443,944
|
|
|
G |
Gstm1 |
glutathione S-transferase mu 1 |
susceptibility |
ISO |
DNA:deletion:cds: (human) |
RGD |
PMID:19279659 |
RGD:7495846 |
NCBI chr 2:198,338,005...198,346,007
|
|
G |
Nos3 |
nitric oxide synthase 3 |
|
ISO |
ClinVar Annotator: match by term: Hypertension resistant to conventional therapy |
ClinVar |
PMID:9737779 PMID:9894802 PMID:10475066 PMID:10510054 PMID:10514107 PMID:11026457 PMID:11354626 PMID:11394896 PMID:11745998 PMID:15007011 PMID:16059745 PMID:16813604 PMID:17165044 PMID:24033266 PMID:25741868 More...
|
|
NCBI chr 4:11,686,088...11,706,604
|
|
G |
Ptprd |
protein tyrosine phosphatase, receptor type, D |
susceptibility |
ISO |
associated with coronary artery disease;DNA:SNP:intron: (rs324498) (human) |
RGD |
PMID:30237584 |
RGD:401976431 |
NCBI chr 5:90,046,993...90,698,977 NCBI chr 5:91,122,354...91,641,754
|
|
|
G |
Nr3c2 |
nuclear receptor subfamily 3, group C, member 2 |
|
ISO |
ClinVar Annotator: match by term: Hypertension, early-onset, autosomal dominant, with severe exacerbation in pregnancy | ClinVar Annotator: match by term: NR3C2-related condition CTD Direct Evidence: marker/mechanism |
OMIM ClinVar CTD |
PMID:10884226 PMID:15126534 PMID:16757525 PMID:16972228 PMID:19571553 PMID:22463955 PMID:25741868 PMID:27780983 PMID:28492532 PMID:32064789 More...
|
|
NCBI chr19:47,619,853...47,964,089
|
|
|
G |
Agt |
angiotensinogen |
treatment |
IEP |
|
RGD |
PMID:22089474 |
RGD:8548895 |
NCBI chr19:69,426,540...69,447,017
|
|
G |
Agtr1a |
angiotensin II receptor, type 1a |
treatment |
IMP |
|
RGD |
PMID:22089474 |
RGD:8548895 |
NCBI chr17:34,383,397...34,435,523
|
|
G |
Cfl1 |
cofilin 1 |
|
IEP |
protein:increased phosphorylation:kidney (rat) |
RGD |
PMID:26450610 |
RGD:11520804 |
NCBI chr 1:212,227,124...212,230,656
|
|
G |
Col1a1 |
collagen type I alpha 1 chain |
|
IEP |
mRNA:increased expression:juxtamedullary cortex (rat) |
RGD |
PMID:17977875 |
RGD:2290351 |
NCBI chr10:80,380,458...80,397,461
|
|
G |
Hp |
haptoglobin |
treatment |
IEP |
|
RGD |
PMID:24029866 |
RGD:11041817 |
NCBI chr19:54,449,151...54,453,701
|
|
G |
Mmp2 |
matrix metallopeptidase 2 |
ameliorates |
IMP |
|
RGD |
PMID:37643020 |
RGD:401827835 |
NCBI chr19:30,327,643...30,355,856
|
|
G |
Mmp2em2Mcwi |
matrix metallopeptidase 2; zinc finger nuclease induced mutant 2, Medical College of Wisconsin |
ameliorates |
IMP |
|
RGD |
PMID:37643020 |
RGD:401827835 |
|
|
G |
Nppb |
natriuretic peptide B |
|
IMP |
|
RGD |
PMID:26063669 |
RGD:12910116 |
NCBI chr 5:163,699,955...163,701,314
|
|
G |
Nppbem2Mcwi |
natriuretic peptide B; zinc finger nuclease induced mutant 2, Medical College of Wisconsin |
|
IMP |
|
RGD |
PMID:26063669 |
RGD:12910116 |
|
|
G |
Postn |
periostin |
disease_progression |
IEP |
mRNA,protein:increased expression:kidney: |
RGD |
PMID:22403621 |
RGD:10041032 |
NCBI chr 2:140,677,774...140,709,304
|
|
G |
Ppara |
peroxisome proliferator activated receptor alpha |
|
IDA |
Strain: SHRSP |
RGD |
PMID:20671072 |
RGD:5509943 |
NCBI chr 7:118,712,261...118,780,723
|
|
G |
Rag1 |
recombination activating 1 |
ameliorates |
IMP |
|
RGD |
PMID:23364523 PMID:23364523 |
RGD:7207429, RGD:7207429 |
NCBI chr 3:87,917,061...87,928,158
|
|
G |
Rag1em1Mcwi |
recombination activating gene 1; zinc finger nuclease induced mutant 1, Medical College of Wisconsin |
ameliorates |
IMP |
|
RGD |
PMID:23364523 |
RGD:7207429 |
|
|
G |
Shc1 |
SHC adaptor protein 1 |
|
IMP IEP |
protein:increased expression:kidney |
RGD |
PMID:27270176 PMID:27270176 |
RGD:12792230, RGD:12792230 |
NCBI chr 2:177,135,649...177,147,257
|
|
G |
Shc1em5Mcwi |
SHC adaptor protein 1; ZFN induced mutant 5, Medical College of Wisconsin |
|
IMP |
|
RGD |
PMID:27270176 |
RGD:12792230 |
|
|
G |
Sirt6 |
sirtuin 6 |
|
ISO |
protein:decreased expression:kidney |
RGD |
PMID:30894089 |
RGD:155260334 |
NCBI chr 7:8,082,312...8,087,776
|
|
|
G |
Ace |
angiotensin I converting enzyme |
treatment severity |
IMP ISO |
protein:increased expression:nephron tubule, kidney interstitium (human) |
RGD |
PMID:10580398 PMID:21346373 |
RGD:12879397, RGD:40818408 |
NCBI chr10:91,410,129...91,430,246
|
|
G |
Ace2 |
angiotensin converting enzyme 2 |
severity |
ISO |
mRNA, protein:decreased expression, increased expression:nephron tubule, kidney interstitium (human) |
RGD |
PMID:21346373 |
RGD:40818408 |
NCBI chr X:30,293,597...30,340,961
|
|
G |
Mir214 |
microRNA 214 |
|
ISO |
RNA:increased expression:kidney |
RGD |
PMID:30049682 |
RGD:38500245 |
NCBI chr13:74,588,374...74,588,481
|
|
|
G |
Crp |
C-reactive protein |
|
ISO |
protein:increased expression:blood: |
RGD |
PMID:21091359 |
RGD:9491786 |
NCBI chr13:87,694,062...87,695,978
|
|
G |
Sox17 |
SRY-box transcription factor 17 |
treatment |
ISO |
|
RGD |
PMID:36200131 |
RGD:329853320 |
NCBI chr 5:15,016,660...15,022,228
|
|
|
G |
Apob |
apolipoprotein B |
|
ISO |
ClinVar Annotator: match by term: Isolated systolic hypertension |
ClinVar |
PMID:25741868 PMID:28492532 |
|
NCBI chr 6:36,563,704...36,603,300
|
|
G |
Bscl2 |
BSCL2 lipid droplet biogenesis associated, seipin |
|
ISO |
ClinVar Annotator: match by term: Isolated systolic hypertension |
ClinVar |
PMID:25741868 PMID:28492532 |
|
NCBI chr 1:205,731,828...205,743,430
|
|
|
G |
Adm |
adrenomedullin |
|
ISO |
protein:increased expression:plasma |
RGD |
PMID:15284680 |
RGD:1625303 |
NCBI chr 1:174,164,178...174,182,372
|
|
G |
Agt |
angiotensinogen |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:2493837 PMID:27428043 |
|
NCBI chr19:69,426,540...69,447,017
|
|
G |
Cyp17a1 |
cytochrome P450, family 17, subfamily a, polypeptide 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:3142437 |
|
NCBI chr 1:245,535,462...245,543,148
|
|
G |
Ren |
renin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:2493837 |
|
NCBI chr13:47,348,312...47,359,539
|
|
|
G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
|
ISO |
protein:decreased expression:plasma |
RGD |
PMID:19222669 |
RGD:5686820 |
NCBI chr11:91,226,524...91,240,244
|
|
|
G |
Gpx3 |
glutathione peroxidase 3 |
|
ISO |
protein:increased expression:plasma |
RGD |
PMID:8476834 |
RGD:401827852 |
NCBI chr10:39,529,335...39,537,406
|
|
|
G |
Cps1 |
carbamoyl-phosphate synthase 1 |
susceptibility |
ISO |
ClinVar Annotator: match by term: Pulmonary hypertension, neonatal, susceptibility to |
ClinVar OMIM |
PMID:8486760 PMID:9536098 PMID:9686343 PMID:9711878 PMID:11388595 PMID:11407344 PMID:11536261 PMID:12655559 PMID:12955727 PMID:14718356 PMID:15050969 PMID:15164414 PMID:15465784 PMID:15617192 PMID:15876373 PMID:16199547 PMID:16708072 PMID:16737834 PMID:17310273 PMID:17576681 PMID:19167850 PMID:19684305 PMID:19793055 PMID:20154341 PMID:20578160 PMID:20800523 PMID:21068339 PMID:21120950 PMID:21767969 PMID:22173106 PMID:22575620 PMID:23649895 PMID:24813853 PMID:24880889 PMID:25741868 PMID:26059772 PMID:26440671 PMID:27150549 PMID:27290639 PMID:27436290 PMID:28444906 PMID:28492532 PMID:28526534 PMID:28658158 PMID:30285816 PMID:31392117 PMID:31435610 PMID:31507628 PMID:31749211 PMID:32154057 PMID:32537019 PMID:32718099 PMID:32934962 PMID:33190319 PMID:33240318 PMID:33309754 PMID:33489762 PMID:33851512 PMID:33924653 PMID:34014557 PMID:34298581 PMID:34440436 PMID:34970092 PMID:36340787 More...
|
|
NCBI chr 9:76,063,863...76,186,739
|
|
|
G |
Acta2 |
actin alpha 2, smooth muscle |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30818366 |
|
NCBI chr 1:241,159,723...241,172,503
|
|
G |
Adrb1 |
adrenoceptor beta 1 |
disease_progression |
ISO |
associated with hypertension;DNA:missense mutations, haplotype:cds:p.S49G(rs1801252),p.R389G (rs1801253)(human): |
RGD |
PMID:19745105 |
RGD:7241815 |
NCBI chr 1:265,777,103...265,780,114
|
|
G |
Alox5 |
arachidonate 5-lipoxygenase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30818366 |
|
NCBI chr 4:151,203,948...151,251,126
|
|
G |
Alpk1 |
alpha-kinase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27542954 |
|
NCBI chr 2:218,801,425...218,924,013
|
|
G |
Col1a1 |
collagen type I alpha 1 chain |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30818366 |
|
NCBI chr10:80,380,458...80,397,461
|
|
G |
Col3a1 |
collagen type III alpha 1 chain |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30818366 |
|
NCBI chr 9:54,866,646...54,902,578
|
|
G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30818366 |
|
NCBI chr 4:152,060,781...152,073,628
|
|
G |
Cxcr4 |
C-X-C motif chemokine receptor 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30818366 |
|
NCBI chr13:42,630,383...42,634,288
|
|
G |
Fgf2 |
fibroblast growth factor 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30818366 |
|
NCBI chr 2:122,164,454...122,218,796
|
|
G |
Hipk2 |
homeodomain interacting protein kinase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28318631 |
|
NCBI chr 4:68,399,358...68,586,404
|
|
G |
Ltb4r |
leukotriene B4 receptor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30818366 |
|
NCBI chr15:29,263,199...29,265,716
|
|
G |
Mthfr |
methylenetetrahydrofolate reductase |
|
ISO |
DNA:transition, transversion:cds:g.677C>T, g.1298A>C (human) |
RGD |
PMID:21613384 |
RGD:6893469 |
NCBI chr 5:163,748,346...163,768,141
|
|
G |
Ptgds |
prostaglandin D2 synthase |
|
ISO |
associated with Hypertension;protein:increased expression:serum, urine |
RGD |
PMID:11882588 |
RGD:1642584 |
NCBI chr 3:28,680,044...28,682,978
|
|
G |
S100a4 |
S100 calcium-binding protein A4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30818366 |
|
NCBI chr 2:178,388,529...178,390,838
|
|
G |
Tgfb1 |
transforming growth factor, beta 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30818366 |
|
NCBI chr 1:90,324,312...90,340,627
|
|
|
G |
6430548M08Rikl |
RIKEN cDNA 6430548M08 gene like |
|
ISO |
ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia |
ClinVar |
|
|
NCBI chr19:48,168,651...48,216,571
|
|
G |
Adad2 |
adenosine deaminase domain containing 2 |
|
ISO |
ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia |
ClinVar |
|
|
NCBI chr19:47,665,288...47,669,433
|
|
G |
Atp2c2 |
ATPase secretory pathway Ca2+ transporting 2 |
|
ISO |
ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia |
ClinVar |
|
|
NCBI chr19:47,754,120...47,811,369
|
|
G |
C19h16orf74 |
similar to human chromosome 16 open reading frame 74 |
|
ISO |
ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia |
ClinVar |
|
|
NCBI chr19:48,660,288...48,686,287
|
|
G |
C19h16orf95 |
similar to human chromosome 16 open reading frame 95 |
|
ISO |
ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia |
ClinVar |
|
|
NCBI chr19:49,605,818...49,618,466
|
|
G |
Cibar2 |
CBY1 interacting BAR domain containing 2 |
|
ISO |
ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia |
ClinVar |
|
|
NCBI chr19:48,217,617...48,229,418
|
|
G |
Cotl1 |
coactosin-like F-actin binding protein 1 |
|
ISO |
ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia |
ClinVar |
|
|
NCBI chr19:47,871,689...47,906,010
|
|
G |
Cox4i1 |
cytochrome c oxidase subunit 4i1 |
|
ISO |
ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia |
ClinVar |
|
|
NCBI chr19:65,630,383...65,636,623
|
|
G |
Cps1 |
carbamoyl-phosphate synthase 1 |
|
ISO |
CACD, OMIM:265380, DNA:polymorphism:T1405N CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:11407344 PMID:11407344 |
RGD:1600716 |
NCBI chr 9:76,063,863...76,186,739
|
|
G |
Crispld2 |
cysteine-rich secretory protein LCCL domain containing 2 |
|
ISO |
ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia |
ClinVar |
|
|
NCBI chr19:48,053,153...48,111,485
|
|
G |
Dnaaf1 |
dynein, axonemal, assembly factor 1 |
|
ISO |
ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia |
ClinVar |
|
|
NCBI chr19:47,624,534...47,652,314
|
|
G |
Emc8 |
ER membrane protein complex subunit 8 |
|
ISO |
ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia |
ClinVar |
|
|
NCBI chr19:48,708,304...48,721,626
|
|
G |
Fbxo31 |
F-box protein 31 |
|
ISO |
ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia |
ClinVar |
|
|
NCBI chr19:49,624,813...49,656,052
|
|
G |
Fendrr |
FOXF1 adjacent non-coding developmental regulatory RNA |
|
ISO |
ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia |
ClinVar |
PMID:25741868 |
|
NCBI chr19:49,127,225...49,152,780
|
|
G |
Foxc2 |
forkhead box C2 |
|
ISO |
ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia |
ClinVar |
|
|
NCBI chr19:66,094,718...66,097,420
|
|
G |
Foxf1 |
forkhead box F1 |
|
ISO ISS |
ClinVar Annotator: match by term: ALVEOLAR CAPILLARY DYSPLASIA WITH MISALIGNMENT OF PULMONARY VEINS AND OTHER CONGENITAL ANOMALIES | ClinVar Annotator: match by term: Alveolar capillary dysplasia with misalignment of pulmonary veins | ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia OMIM:265380 CTD Direct Evidence: marker/mechanism |
OMIM ClinVar MouseDO CTD |
PMID:15520767 PMID:19500772 PMID:23505205 PMID:24033266 PMID:25741868 PMID:27071622 PMID:27439648 PMID:27855150 PMID:28469849 PMID:28492532 PMID:30380203 PMID:36474027 More...
|
|
NCBI chr19:49,153,949...49,157,741
|
|
G |
Foxl1 |
forkhead box L1 |
|
ISO |
ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia |
ClinVar |
|
|
NCBI chr19:49,197,269...49,200,682
|
|
G |
Gins2 |
GINS complex subunit 2 |
|
ISO |
ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia |
ClinVar |
|
|
NCBI chr19:65,535,492...65,548,270
|
|
G |
Gse1 |
Gse1 coiled-coil protein |
|
ISO |
ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia |
ClinVar |
|
|
NCBI chr19:65,182,678...65,538,183
|
|
G |
Hsdl1 |
hydroxysteroid dehydrogenase like 1 |
|
ISO |
ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia |
ClinVar |
|
|
NCBI chr19:47,615,794...47,631,892
|
|
G |
Irf8 |
interferon regulatory factor 8 |
|
ISO |
ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia |
ClinVar |
|
|
NCBI chr19:48,790,581...48,812,363
|
|
G |
Itgam |
integrin subunit alpha M |