RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: common cold
Accession: DOID:10459
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Definition: An upper respiratory tract disease which involves inflammation of the mucous membranes of the nose, throat, eyes, and eustachian tubes with watery then purulent discharge. This is an acute contagious disease caused by rhinoviruses, human parainfluenza viruses, human respiratory syncytial virus, influenza viruses, adenoviruses, enteroviruses, or metapneumovirus. (DO)
Synonyms: exact_synonym: Acute viral rhinopharyngitis; Catarrh; Catarrhs; Common Colds; acute coryza; acute nasopharyngitis; acute rhinitis; rhino-sinusitis
related_synonym: Rhinovirus Infection
xref: EFO:0007214 ; ICD9CM:460 ; MESH:D003139 ; MONDO:0005709 ; NCI:C34500 ; NCI:C78599
For additional species annotation, visit the
Alliance of Genome Resources .
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Alox5
arachidonate 5-lipoxygenase
ISO
protein:increased expression:bronchus
RGD
PMID:11865407
RGD:4890421
NCBI chrNW_004624966:168,244...220,430
Ensembl chrNW_004624966:168,250...220,522
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Alox5ap
arachidonate 5-lipoxygenase activating protein
ISO
protein:increased expression:bronchus
RGD
PMID:11865407
RGD:4890421
NCBI chrNW_004624776:7,475,269...7,646,805
Ensembl chrNW_004624776:7,475,200...7,506,283
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Cx3cl1
C-X3-C motif chemokine ligand 1
ISO
RGD
PMID:20696083
RGD:4140458
NCBI chrNW_004624746:28,677,956...28,688,638
Ensembl chrNW_004624746:28,677,709...28,689,122
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Cxcl10
C-X-C motif chemokine ligand 10
ISO
protein:increased expression:respiratory system fluid/secretion
RGD
PMID:15764644
RGD:5135489
NCBI chrNW_004624757:14,989,241...14,991,650
Ensembl chrNW_004624757:14,989,084...14,991,910
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Cxcl8
C-X-C motif chemokine ligand 8
treatment
ISO
RGD
PMID:28343401
RGD:150521550
NCBI chrNW_004624730:1,744,097...1,747,206
Ensembl chrNW_004624730:1,743,916...1,747,293
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Il10
interleukin 10
ISO
RGD
PMID:20696083
RGD:4140458
NCBI chrNW_004624807:4,687,249...4,691,658
Ensembl chrNW_004624807:4,687,176...4,691,732
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Il1a
interleukin 1 alpha
ISO
protein:increased expression:nasal mucus
RGD
PMID:10358201
RGD:4143183
NCBI chrNW_004624749:12,795,967...12,805,658
Ensembl chrNW_004624749:12,795,946...12,805,154
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Il1b
interleukin 1 beta
ISO
protein:increased expression:nasal mucus
RGD
PMID:7734976
RGD:7401200
NCBI chrNW_004624749:12,852,128...12,858,478
Ensembl chrNW_004624749:12,852,021...12,858,760
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Il1rn
interleukin 1 receptor antagonist
ISO
protein:increased expression:nasal mucus
RGD
PMID:10358201 PMID:18279051
RGD:4143183 RGD:4143207
NCBI chrNW_004624749:13,210,365...13,224,471
Ensembl chrNW_004624749:13,210,476...13,225,890
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Il33
interleukin 33
ISO
protein:increased expression:nasal mucus
RGD
PMID:28471975
RGD:38596342
NCBI chrNW_004624736:10,733,944...10,786,188
Ensembl chrNW_004624736:10,764,486...10,784,864
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Il4
interleukin 4
ISO
associated with Asthma;mRNA, protein:increased expression:alveolar macrophage, respiratory system fluid/secretion
RGD
PMID:20644177
RGD:4140459
NCBI chrNW_004624733:39,412,800...39,420,079
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Prdx5
peroxiredoxin 5
ISO
associated with asthma;protein:increased expression:sputum (human)
RGD
PMID:18219526
RGD:41404684
NCBI chrNW_004624767:21,995,542...21,998,609
Ensembl chrNW_004624767:21,995,681...21,997,149
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