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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:common cold
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Accession:DOID:10459 term browser browse the term
Definition:An upper respiratory tract disease which involves inflammation of the mucous membranes of the nose, throat, eyes, and eustachian tubes with watery then purulent discharge. This is an acute contagious disease caused by rhinoviruses, human parainfluenza viruses, human respiratory syncytial virus, influenza viruses, adenoviruses, enteroviruses, or metapneumovirus. (DO)
Synonyms:exact_synonym: Acute viral rhinopharyngitis;   Catarrh;   Catarrhs;   Common Colds;   acute coryza;   acute nasopharyngitis;   acute rhinitis;   rhino-sinusitis
 related_synonym: Rhinovirus Infection
 xref: EFO:0007214;   ICD9CM:460;   MESH:D003139;   MONDO:0005709;   NCI:C34500;   NCI:C78599
For additional species annotation, visit the Alliance of Genome Resources.


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common cold term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase ISO protein:increased expression:bronchus RGD PMID:11865407 RGD:4890421 NCBI chrNW_004624966:168,244...220,430
Ensembl chrNW_004624966:168,250...220,522
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein ISO protein:increased expression:bronchus RGD PMID:11865407 RGD:4890421 NCBI chrNW_004624776:7,475,269...7,646,805
Ensembl chrNW_004624776:7,475,200...7,506,283
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 ISO RGD PMID:20696083 RGD:4140458 NCBI chrNW_004624746:28,677,956...28,688,638
Ensembl chrNW_004624746:28,677,709...28,689,122
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:15764644 RGD:5135489 NCBI chrNW_004624757:14,989,241...14,991,650
Ensembl chrNW_004624757:14,989,084...14,991,910
JBrowse link
G Cxcl8 C-X-C motif chemokine ligand 8 treatment ISO RGD PMID:28343401 RGD:150521550 NCBI chrNW_004624730:1,744,097...1,747,206
Ensembl chrNW_004624730:1,743,916...1,747,293
JBrowse link
G Il10 interleukin 10 ISO RGD PMID:20696083 RGD:4140458 NCBI chrNW_004624807:4,687,249...4,691,658
Ensembl chrNW_004624807:4,687,176...4,691,732
JBrowse link
G Il1a interleukin 1 alpha ISO protein:increased expression:nasal mucus RGD PMID:10358201 RGD:4143183 NCBI chrNW_004624749:12,795,967...12,805,658
Ensembl chrNW_004624749:12,795,946...12,805,154
JBrowse link
G Il1b interleukin 1 beta ISO protein:increased expression:nasal mucus RGD PMID:7734976 RGD:7401200 NCBI chrNW_004624749:12,852,128...12,858,478
Ensembl chrNW_004624749:12,852,021...12,858,760
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO protein:increased expression:nasal mucus RGD PMID:10358201 PMID:18279051 RGD:4143183 RGD:4143207 NCBI chrNW_004624749:13,210,365...13,224,471
Ensembl chrNW_004624749:13,210,476...13,225,890
JBrowse link
G Il33 interleukin 33 ISO protein:increased expression:nasal mucus RGD PMID:28471975 RGD:38596342 NCBI chrNW_004624736:10,733,944...10,786,188
Ensembl chrNW_004624736:10,764,486...10,784,864
JBrowse link
G Il4 interleukin 4 ISO associated with Asthma;mRNA, protein:increased expression:alveolar macrophage, respiratory system fluid/secretion RGD PMID:20644177 RGD:4140459 NCBI chrNW_004624733:39,412,800...39,420,079 JBrowse link
G Prdx5 peroxiredoxin 5 ISO associated with asthma;protein:increased expression:sputum (human) RGD PMID:18219526 RGD:41404684 NCBI chrNW_004624767:21,995,542...21,998,609
Ensembl chrNW_004624767:21,995,681...21,997,149
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14231
    disease of anatomical entity 13933
      respiratory system disease 4527
        Respiratory Tract Infections 408
          common cold 12
Path 2
Term Annotations click to browse term
  disease 14231
    disease by infectious agent 1938
      viral infectious disease 1485
        RNA Virus Infections 1225
          Picornaviridae Infections 47
            common cold 12
paths to the root