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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:common cold
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Accession:DOID:10459 term browser browse the term
Definition:An upper respiratory tract disease which involves inflammation of the mucous membranes of the nose, throat, eyes, and eustachian tubes with watery then purulent discharge. This is an acute contagious disease caused by rhinoviruses, human parainfluenza viruses, human respiratory syncytial virus, influenza viruses, adenoviruses, enteroviruses, or metapneumovirus. (DO)
Synonyms:exact_synonym: Acute viral rhinopharyngitis;   Catarrh;   Catarrhs;   Common Colds;   acute coryza;   acute nasopharyngitis;   acute rhinitis;   rhino-sinusitis
 related_synonym: Rhinovirus Infection
 xref: EFO:0007214;   ICD9CM:460;   MESH:D003139;   MONDO:0005709;   NCI:C34500;   NCI:C78599
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
common cold term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5 arachidonate 5-lipoxygenase ISO protein:increased expression:bronchus RGD PMID:11865407 RGD:4890421 NCBI chr28:2,170,920...2,218,765
Ensembl chr28:2,170,920...2,219,609 		JBrowse link
G ALOX5AP arachidonate 5-lipoxygenase activating protein ISO protein:increased expression:bronchus RGD PMID:11865407 RGD:4890421 NCBI chr25:9,320,868...9,351,056
Ensembl chr25:9,320,864...9,351,836 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 ISO RGD PMID:20696083 RGD:4140458 NCBI chr 2:59,022,794...59,032,095
Ensembl chr 2:59,022,794...59,032,095 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:15764644 RGD:5135489 NCBI chr32:598,406...599,925
Ensembl chr32:597,987...599,979 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 treatment ISO RGD PMID:28343401 RGD:150521550 NCBI chr13:62,435,035...62,438,354
Ensembl chr13:62,434,422...62,438,354 		JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 ISO RGD PMID:19864593 RGD:5131210 NCBI chr37:24,831,351...24,846,387
Ensembl chr37:24,843,171...24,844,247 		JBrowse link
G DEFB4A defensin, beta 4A ISO mRNA, protein:increased expression:nasal cavity epithelium, nasal mucus RGD PMID:15034083 RGD:4892264 NCBI chr16:58,953,916...58,956,407
Ensembl chr16:58,953,916...58,956,407 		JBrowse link
G IL10 interleukin 10 ISO RGD PMID:20696083 RGD:4140458 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057 		JBrowse link
G IL1A interleukin 1 alpha ISO protein:increased expression:nasal mucus RGD PMID:10358201 RGD:4143183 NCBI chr17:36,969,581...36,979,445
Ensembl chr17:36,970,573...36,979,435 		JBrowse link
G IL1B interleukin 1 beta ISO protein:increased expression:nasal mucus RGD PMID:7734976 RGD:7401200 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458 		JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO protein:increased expression:nasal mucus RGD PMID:10358201 PMID:18279051 RGD:4143183 RGD:4143207 NCBI chr17:37,236,690...37,250,424
Ensembl chr17:37,212,751...37,249,329 		JBrowse link
G IL33 interleukin 33 ISO protein:increased expression:nasal mucus RGD PMID:28471975 RGD:38596342 NCBI chr11:27,219,878...27,256,723
Ensembl chr11:27,219,878...27,256,721 		JBrowse link
G IL4 interleukin 4 ISO associated with Asthma;mRNA, protein:increased expression:alveolar macrophage, respiratory system fluid/secretion RGD PMID:20644177 RGD:4140459 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534 		JBrowse link
G LOC106557449 alveolar macrophage chemotactic factor-like ISO associated with Asthma RGD PMID:12751040 RGD:5135264 NCBI chr13:62,514,244...62,516,439
Ensembl chr13:62,513,898...62,515,218 		JBrowse link
G PRDX5 peroxiredoxin 5 ISO associated with asthma;protein:increased expression:sputum (human) RGD PMID:18219526 RGD:41404684 NCBI chr18:52,750,977...52,754,432 JBrowse link
G TSLP thymic stromal lymphopoietin ISO protein:increased expression:nasal mucus (human) RGD PMID:28471975 RGD:38596342 NCBI chr 3:1,502,469...1,507,696
Ensembl chr 3:1,503,188...1,507,696 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15755
    disease of anatomical entity 15375
      respiratory system disease 4973
        Respiratory Tract Infections 470
          common cold 16
Path 2
Term Annotations click to browse term
  disease 15755
    disease by infectious agent 2168
      viral infectious disease 1663
        RNA Virus Infections 1364
          Picornaviridae Infections 55
            common cold 16
paths to the root