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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:common cold
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Accession:DOID:10459 term browser browse the term
Definition:An upper respiratory tract disease which involves inflammation of the mucous membranes of the nose, throat, eyes, and eustachian tubes with watery then purulent discharge. This is an acute contagious disease caused by rhinoviruses, human parainfluenza viruses, human respiratory syncytial virus, influenza viruses, adenoviruses, enteroviruses, or metapneumovirus. (DO)
Synonyms:exact_synonym: Acute viral rhinopharyngitis;   Catarrh;   Catarrhs;   Common Colds;   acute coryza;   acute nasopharyngitis;   acute rhinitis;   rhino-sinusitis
 related_synonym: Rhinovirus Infection
 xref: EFO:0007214;   ICD9CM:460;   MESH:D003139;   MONDO:0005709;   NCI:C34500;   NCI:C78599
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
common cold term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5 arachidonate 5-lipoxygenase ISO protein:increased expression:bronchus RGD PMID:11865407 RGD:4890421 NCBI chr10:42,461,398...42,531,576
Ensembl chr10:45,639,946...45,710,016 		JBrowse link
G ALOX5AP arachidonate 5-lipoxygenase activating protein ISO protein:increased expression:bronchus RGD PMID:11865407 RGD:4890421 NCBI chr13:12,012,399...12,041,557
Ensembl chr13:30,425,510...30,476,607 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 ISO RGD PMID:20696083 RGD:4140458 NCBI chr16:37,646,447...37,659,078
Ensembl chr16:56,779,065...56,791,760 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:15764644 RGD:5135489 NCBI chr 4:48,182,355...48,184,733
Ensembl chr 4:54,020,204...54,022,606 		JBrowse link
G CXCL5 C-X-C motif chemokine ligand 5 ISO associated with Asthma RGD PMID:12751040 RGD:5135264 NCBI chr 4:50,192,665...50,195,642
Ensembl chr 4:56,024,848...56,027,989 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 treatment ISO RGD PMID:28343401 RGD:150521550 NCBI chr 4:50,452,857...50,456,015
Ensembl chr 4:56,286,708...56,288,083 		JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 ISO RGD PMID:19864593 RGD:5131210 NCBI chr2B:105,387,198...105,400,533
Ensembl chr2B:223,997,066...223,998,148 		JBrowse link
G IL10 interleukin 10 ISO RGD PMID:20696083 RGD:4140458 NCBI chr 1:182,369,234...182,374,207
Ensembl chr 1:186,648,289...186,653,371 		JBrowse link
G IL1A interleukin 1 alpha ISO protein:increased expression:nasal mucus RGD PMID:10358201 RGD:4143183 NCBI chr2A:89,273,482...89,284,421
Ensembl chr2A:113,784,854...113,795,801 		JBrowse link
G IL1B interleukin 1 beta ISO protein:increased expression:nasal mucus RGD PMID:7734976 RGD:7401200 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424 		JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO protein:increased expression:nasal mucus RGD PMID:10358201 PMID:18279051 RGD:4143183 RGD:4143207 NCBI chr2A:88,991,646...89,008,013
Ensembl chr2A:114,061,182...114,078,839 		JBrowse link
G IL33 interleukin 33 ISO protein:increased expression:nasal mucus RGD PMID:28471975 RGD:38596342 NCBI chr 9:6,027,014...6,069,540
Ensembl chr 9:6,234,178...6,248,624 		JBrowse link
G IL4 interleukin 4 ISO associated with Asthma;mRNA, protein:increased expression:alveolar macrophage, respiratory system fluid/secretion RGD PMID:20644177 RGD:4140459 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581 		JBrowse link
G LOC100972354 interferon alpha-2 treatment ISO RGD PMID:6381610 RGD:40886344 NCBI chr 9:21,245,017...21,246,210
Ensembl chr 9:21,863,062...21,863,736 		JBrowse link
G LOC100976904 growth-regulated alpha protein ISO associated with Pulmonary Disease, Chronic Obstructive;protein:increased expression:respiratory epithelial cell RGD PMID:20395558 RGD:4145446 NCBI chr 4:50,325,248...50,327,165
Ensembl chr 4:56,153,899...56,159,474 		JBrowse link
G PRDX5 peroxiredoxin 5 ISO associated with asthma;protein:increased expression:sputum (human) RGD PMID:18219526 RGD:41404684 NCBI chr11:59,675,138...59,678,804
Ensembl chr11:63,020,097...63,023,624 		JBrowse link
G TSLP thymic stromal lymphopoietin ISO protein:increased expression:nasal mucus (human) RGD PMID:28471975 RGD:38596342 NCBI chr 5:106,440,136...106,446,849
Ensembl chr 5:112,242,490...112,250,130 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15835
    disease of anatomical entity 15491
      respiratory system disease 4885
        Respiratory Tract Infections 480
          common cold 17
Path 2
Term Annotations click to browse term
  disease 15835
    disease by infectious agent 2147
      viral infectious disease 1654
        RNA Virus Infections 1373
          Picornaviridae Infections 57
            common cold 17
paths to the root