prostate cancer - Ontology Report - Rat Genome Database

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RGD DISEASE ONTOLOGY - ANNOTATIONS

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RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:	prostate cancer	go back to main search page
Accession:	DOID:10283	browse the term
Definition:	A male reproductive organ cancer that is located_in the prostate. (DO)
Synonyms:	exact_synonym:	NGP - new growth of prostate; cancer of prostate; cancer of the prostate; malignant tumor of prostate; malignant tumor of the prostate; prostate cancers; prostatic cancer; tumor of the prostate
	narrow_synonym:	GEN1-RELATED CONDITION; GEN1-RELATED PROSTATE CANCER; PROSTATE CANCER, PROGRESSION AND METASTASIS OF; familial prostate cancer
	related_synonym:	CYP3A4 PROMOTER POLYMORPHISM, Cyp3a4-v; prostate cancer, susceptibility to; prostate cancer, susceptibility to, in African Americans
	xref:	EFO:0000196; ICD10CM:C61; ICD9CM:185; MIM:176807; MONDO:0008315; NCI:C3343; NCI:C7378; ORDO:1331
For additional species annotation, visit the Alliance of Genome Resources.

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Genes (803)

prostate cancer

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily A member 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:39,689,133...39,732,466
Ensembl chr 3:39,698,895...39,732,978

G

ATP binding cassette subfamily C member 4 (PEL blood group)

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:64,089,149...64,309,831

G

ATP binding cassette subfamily E member 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:83,302,055...83,353,208
Ensembl chr 8:83,299,322...83,353,109

G

ATP binding cassette subfamily F member 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:122,102,939...122,112,896
Ensembl chr13:122,105,344...122,113,559

G

ATP binding cassette subfamily G member 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:46,364,546...46,380,545
Ensembl chr 9:46,364,936...46,380,544

G

ankyrin repeat and BTB domain containing 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:12,754,535...13,071,050
Ensembl chr 5:12,754,539...13,069,527

G

acid phosphatase 3

disease_progression

PSA/PAP (prostatic acid phosphatase) ratio - a valuable prognostic indicator in men with Stage IV prostate cancer
OMIM:176807 | OMIM:300147 | OMIM:300704 | OMIM:601518 | OMIM:602759 | OMIM:608656 | OMIM:608658 | OMIM:609299 | OMIM:609558 | OMIM:610321 | OMIM:610997 | OMIM:611100 | OMIM:611868 | OMIM:611928 | OMIM:611955 | OMIM:611958 | OMIM:611959

PMID:16024648 PMID:17991541

RGD:2301054 RGD:2301055

NCBI chr13:73,471,837...73,530,778
Ensembl chr13:73,471,889...73,530,011

G

acrosomal vesicle protein 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:52,803,378...52,809,975
Ensembl chr 9:52,803,381...52,809,975

G

acyl-CoA synthetase long chain family member 3

treatment
disease_progression

NCBI chr15:124,741,986...124,816,955
Ensembl chr15:124,765,854...124,816,960

G

ADAM metallopeptidase with thrombospondin type 1 motif 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:68,675,067...68,948,537
Ensembl chr 8:68,675,070...68,948,414

G

adenosine deaminase tRNA specific 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:12,076,319...12,107,937
Ensembl chr 6:12,076,356...12,108,088

G

ADRM1 26S proteasome ubiquitin receptor

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:61,692,923...61,698,138
Ensembl chr17:61,692,945...61,698,144

G

adenylosuccinate lyase

severity

protein:increased activity:tumor (human)

NCBI chr 5:8,027,799...8,045,480
Ensembl chr 5:8,025,508...8,047,603

G

alpha fetoprotein

protein:increased expression:serum

NCBI chr 8:69,677,690...69,698,864
Ensembl chr 8:69,677,690...69,698,864

G

ArfGAP with GTPase domain, ankyrin repeat and PH domain 2

protein:increased expression:prostate

NCBI chr 5:23,015,777...23,035,943
Ensembl chr 5:23,017,176...23,033,517

G

AGBL carboxypeptidase 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:161,953,495...163,216,282

G

advanced glycosylation end-product specific receptor

mRNA:increased expression:prostate gland (human)

NCBI chr 7:24,218,116...24,221,162
Ensembl chr 7:24,218,120...24,221,162

G

1-acylglycerol-3-phosphate O-acyltransferase 2

ClinVar Annotator: match by term: Malignant tumor of prostate

G

aryl hydrocarbon receptor repressor

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:79,730,920...79,810,183
Ensembl chr16:79,730,926...79,810,188

G

apoptosis inducing factor mitochondria associated 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:106,676,596...106,708,290
Ensembl chr X:106,670,520...106,708,317

G

A-kinase anchoring protein 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:33,396,473...33,410,395
Ensembl chr12:33,396,473...33,411,440

G

aldo-keto reductase family 1, member C1

disease_progression

protein:increased expression:epithelium:
ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:24571686

NCBI chr10:65,580,297...65,594,998
Ensembl chr10:65,576,464...65,678,248

G

AKT serine/threonine kinase 1

severity

DNA:SNPs:5' utr, intron: (rs1130214, rs2494738) (human)

G

AKT serine/threonine kinase 2

DNA:SNP: :rs7254617 (human)

NCBI chr 6:48,555,785...48,620,472
Ensembl chr 6:48,555,795...48,587,919

G

AKT serine/threonine kinase 3

severity

DNA:SNP: :rs2125230 (human)

NCBI chr10:16,441,465...16,741,745
Ensembl chr10:16,441,447...16,741,337

G

aldehyde dehydrogenase 5 family member A1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:19,351,485...19,375,515
Ensembl chr 7:19,351,361...19,379,098

G

aldehyde dehydrogenase 9 family member A1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:85,029,914...85,057,650

G

arachidonate 12-lipoxygenase, 12S type

disease_progression

mRNA:increased expression:prostate gland

NCBI chr12:52,401,861...52,414,913
Ensembl chr12:52,401,810...52,414,903

G

adenosylmethionine decarboxylase 1

protein:increased expression:prostate

NCBI chr 1:76,839,448...76,863,745
Ensembl chr 1:76,839,731...76,863,738

G

angiogenin

PMID:11948474 PMID:19276260

RGD:2325697 RGD:2325707

NCBI chr 7:78,249,479...78,262,846
Ensembl chr 7:78,249,487...78,250,138

G

ankyrin repeat domain 12

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:98,697,207...98,814,727
Ensembl chr 6:98,697,174...98,815,336

G

anoctamin 9

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:232,761...250,966
Ensembl chr 2:232,194...250,935

G

annexin A7

protein:decreased expression:prostate gland

NCBI chr14:76,205,238...76,234,646
Ensembl chr14:76,205,232...76,234,631

G

adaptor related protein complex 3 subunit beta 1

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr 2:86,875,922...87,142,722
Ensembl chr 2:86,873,290...87,142,768

G

APC regulator of WNT signaling pathway

disease_progression

OMIM:176807 | OMIM:300147 | OMIM:300704 | OMIM:601518 | OMIM:602759 | OMIM:608656 | OMIM:608658 | OMIM:609299 | OMIM:609558 | OMIM:610321 | OMIM:610997 | OMIM:611100 | OMIM:611868 | OMIM:611928 | OMIM:611955 | OMIM:611958 | OMIM:611959

NCBI chr 2:116,913,354...116,985,303
Ensembl chr 2:116,812,582...117,034,887

G

androgen receptor

treatment
no_association

ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: Prostate cancer
african-american men

PMID:1307250 PMID:1631125 PMID:1779964 PMID:2594783 PMID:7671849 More...

RGD:10043311 RGD:1578686

NCBI chr X:53,609,113...53,806,778
Ensembl chr X:53,609,176...53,800,677

G

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:143,304,076...143,327,588
Ensembl chr 2:143,304,080...143,327,588

G

Rho GTPase activating protein 20

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:38,471,049...38,582,221
Ensembl chr 9:38,474,865...38,582,242

G

Rho guanine nucleotide exchange factor 15

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:53,495,409...53,506,373
Ensembl chr12:53,495,453...53,506,352

G

Rho guanine nucleotide exchange factor 25

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:22,873,502...22,880,830
Ensembl chr 5:22,873,736...22,880,827

G

Rho guanine nucleotide exchange factor 40

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:78,043,995...78,067,546
Ensembl chr 7:78,042,057...78,064,913

G

armadillo repeat containing 12

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:31,583,544...31,601,790
Ensembl chr 7:31,586,797...31,603,600

G

cAMP regulated phosphoprotein 21

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:20,955,414...21,088,424
Ensembl chr13:20,934,846...21,088,420

G

acid sensing ion channel subunit 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:41,726,987...42,031,997
Ensembl chr12:41,727,002...42,031,991

G

aspartic peptidase retroviral like 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:72,323,958...72,536,564
Ensembl chr 3:72,493,129...72,493,908

G

activating transcription factor 3

disease_progression
treatment

PMID:26522727 PMID:26944919

RGD:13506816 RGD:13506817

NCBI chr 9:130,772,259...130,829,678
Ensembl chr 9:130,772,262...130,785,506

G

autophagy related 13

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:15,856,859...15,916,122
Ensembl chr 2:15,856,860...15,916,109

G

atlastin GTPase 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:8,361,579...8,408,920
Ensembl chr 2:8,361,774...8,408,917

G

ATM serine/threonine kinase

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23807571 PMID:25614872 PMID:25741868 PMID:28492532

NCBI chr 9:36,620,656...36,759,555
Ensembl chr 9:36,620,657...36,759,552

G

ATPase Na+/K+ transporting subunit alpha 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:104,353,506...104,384,321
Ensembl chr 4:104,353,506...104,384,680

G

ATPase plasma membrane Ca2+ transporting 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:64,336,354...64,445,669
Ensembl chr 9:64,336,499...64,445,663

G

ATPase H+ transporting V0 subunit a1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:20,288,409...20,344,142
Ensembl chr12:20,288,411...20,344,127

G

alpha-2-glycoprotein 1, zinc-binding

protein:increased expression:serum

NCBI chr 3:7,867,521...7,874,857

G

beta-1,3-galactosyltransferase 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:73,772,833...74,340,060
Ensembl chr15:74,335,112...74,339,380

G

BRISC and BRCA1 A complex member 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:110,897,250...111,328,414
Ensembl chr 3:110,897,256...111,328,385

G

BAG cochaperone 1

DNA, protein:amplification, increased expression:prostate gland

NCBI chr10:33,227,530...33,240,731
Ensembl chr10:33,227,337...33,242,230

G

BCL2 associated X, apoptosis regulator

PMID:17575222 PMID:18444130

RGD:1643354 RGD:2292907

NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,147

G

BCL2 apoptosis regulator

disease_progression

PMID:16984224 PMID:17850375 PMID:18084610

RGD:2292512 RGD:2293015 RGD:2293017

NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879

G

BEN domain containing 5

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:162,964,176...163,011,225
Ensembl chr 6:162,964,216...163,011,583

G

BICRA like chromatin remodeling complex associated protein

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:37,852,153...37,933,599
Ensembl chr 7:37,824,242...37,933,593

G

baculoviral IAP repeat containing 5

severity

mRNA:increased expression:prostate gland

PMID:17804712 PMID:18336887

RGD:2293091 RGD:2293100

NCBI chr12:3,747,276...3,755,214
Ensembl chr12:3,747,279...3,755,215

G

bone morphogenetic protein 2

disease_progression
susceptibility

DNA:amplification:prostate gland

PMID:15042598 PMID:17656261

RGD:2289030 RGD:2299981

NCBI chr17:15,750,487...15,762,982
Ensembl chr17:15,749,835...15,761,195

G

bone morphogenetic protein 6

protein:increased expression:prostate

NCBI chr 7:5,058,817...5,208,868
Ensembl chr 7:5,058,817...5,210,270

G

bone morphogenetic protein 7

susceptibility

protein:decreased expression:prostate gland
DNA:amplification:prostate gland

PMID:15861517 PMID:17656261

RGD:2289030 RGD:2289031

NCBI chr17:57,567,770...57,676,516
Ensembl chr17:57,584,956...57,675,986

G

BCL2 interacting protein 5

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:32,034,424...32,054,644
Ensembl chr 7:32,035,342...32,054,632

G

BRCA1 DNA repair associated

no_association
severity

ClinVar Annotator: match by term: Malignant tumor of prostate
DNA:deletions: :185_186del,1294_1333del,3875_3878del

PMID:10398279 PMID:12491487 PMID:15235020 PMID:15447980 PMID:16267036 More...

RGD:2289042 RGD:734657

NCBI chr12:19,788,087...19,854,515
Ensembl chr12:19,786,020...19,854,668

G

BRCA2 DNA repair associated

disease_progression

DNA:mutation
ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: Prostate cancer

RGD
ClinVar
OMIM

PMID:1 PMID:278235 PMID:1772447 PMID:2200631 PMID:2661312 More...

NCBI chr11:8,805,950...8,858,128
Ensembl chr11:8,805,913...8,857,793

G

BRF2 RNA polymerase III transcription initiation factor subunit

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:25741868

NCBI chr15:48,568,207...48,573,036
Ensembl chr15:48,568,202...48,573,029

G

BTB domain containing 16

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:131,864,394...131,920,317
Ensembl chr14:131,861,480...131,920,479

G

C2 calcium dependent domain containing 6

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:105,159,814...105,250,918
Ensembl chr15:105,105,234...105,250,563

G

complement C3a receptor 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:63,088,778...63,098,750
Ensembl chr 5:63,088,778...63,098,750

G

complement C5

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:260,995,662...261,088,868
Ensembl chr 1:260,995,668...261,133,483

G

calcineurin binding protein 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:49,686,196...49,787,723
Ensembl chr14:49,686,196...49,787,688

G

calcium voltage-gated channel subunit alpha1 D

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:35,568,534...35,911,483
Ensembl chr13:35,436,519...35,909,662

G

cell adhesion molecule 1

DNA:hypermethylation:promoter

NCBI chr 9:42,644,487...42,984,934
Ensembl chr 9:42,644,431...42,985,017

G

cell adhesion molecule 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:91,227,362...91,260,125
Ensembl chr 4:91,227,363...91,260,097

G

calcium dependent secretion activator

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:43,979,694...44,482,985

G

calcium/calmodulin dependent protein kinase II inhibitor 1

disease_progression

mRNA, protein:decreased expression:prostate gland

PMID:25003983 PMID:31762801

RGD:18337271 RGD:18337280

NCBI chr 6:78,730,204...78,734,232
Ensembl chr 6:78,730,206...78,733,740

G

cullin associated and neddylation dissociated 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:31,657,508...31,700,163
Ensembl chr 5:31,657,501...31,700,163

G

calpain 6

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:91,258,696...91,288,128
Ensembl chr X:91,258,688...91,288,077

G

calcium/calmodulin dependent serine protein kinase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:37,166,973...37,535,723
Ensembl chr X:37,167,577...37,536,160

G

caspase 1, apoptosis-related cysteine peptidase

protein:decreased expression:prostate gland

NCBI chr 9:35,188,066...35,199,364
Ensembl chr 9:35,186,420...35,200,328

G

caspase 3

NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213

G

calcium sensing receptor

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:138,279,785...138,364,934
Ensembl chr13:138,280,364...138,364,252

G

caveolin 1

disease_progression

protein:increased expression:serum
DNA:hypermethylation:promoter

PMID:11170154 PMID:14506154 PMID:15948133

RGD:2289104 RGD:2289109 RGD:2289112

NCBI chr18:29,648,120...29,682,451
Ensembl chr18:29,649,992...29,682,465

G

chromobox 1

protein:increased expression:prostate:

NCBI chr12:24,319,104...24,351,057
Ensembl chr12:24,315,518...24,351,052

G

chromobox 3

protein:increased expression:prostate:

NCBI chr18:46,193,138...46,205,114
Ensembl chr18:46,193,140...46,204,714

G

chromobox 5

protein:increased expression:prostate:

NCBI chr 5:19,446,083...19,484,527
Ensembl chr 5:19,446,086...19,484,463

G

chromobox 7

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:9,070,312...9,090,467
Ensembl chr 5:9,070,353...9,087,634

G

chibby 1, beta catenin antagonist

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:9,346,087...9,358,155

G

coiled-coil domain containing 171

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:206,788,323...207,143,054
Ensembl chr 1:206,792,212...207,142,837

G

cyclin A1

disease_progression

human gene, mouse model

NCBI chr11:12,396,149...12,405,357
Ensembl chr11:12,396,301...12,405,350

G

cyclin B1

NCBI chr16:47,338,239...47,348,385
Ensembl chr16:47,338,110...47,348,377

G

cyclin D1

NCBI chr 2:3,621,242...3,633,380
Ensembl chr 2:3,621,246...3,633,296

G

cyclin D2

disease_progression

DNA, mRNA:hyperymethylation, decreased expression:promoter, prostate gland

PMID:16322291 PMID:17016690

RGD:151665170 RGD:2289151

NCBI chr 5:66,092,483...66,114,575
Ensembl chr 5:66,087,379...66,114,571

G

cyclin D3

disease_progression

NCBI chr 7:37,087,336...37,182,462
Ensembl chr 7:37,082,097...37,181,366

G

CD2 molecule

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:103,963,802...103,976,971
Ensembl chr 4:103,963,345...103,977,292

G

CD244 molecule

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:89,668,221...89,700,974
Ensembl chr 4:89,668,239...89,700,972

G

CD2 associated protein

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:42,218,016...42,332,523
Ensembl chr 7:42,218,290...42,332,518

G

CD44 molecule

disease_progression

DNA:hypermethylation:prostate gland

NCBI chr 2:25,788,699...25,884,209
Ensembl chr 2:25,788,703...25,884,153

G

CD55 molecule (Cromer blood group)

PMID:16533428 PMID:18288643

RGD:2326167 RGD:2326168

NCBI chr 9:67,933,069...67,960,380

G

CD82 molecule

disease_progression

protein:decreased expression:prostate gland

NCBI chr 2:17,751,153...17,803,172
Ensembl chr 2:17,750,660...17,803,126

G

cell division cycle 25A

G

cell division cycle 25B

protein:increased expression:prostate gland

NCBI chr17:31,910,824...31,929,418
Ensembl chr17:31,910,825...31,929,242

G

cell division cycle 25C

mRNA, protein:alternative form, increased expression, increased activity:prostate gland

PMID:12896904 PMID:16000564 PMID:16140946 PMID:17460776

RGD:2756028 RGD:2774210 RGD:2776427 RGD:4105453

NCBI chr 2:140,289,156...140,323,696
Ensembl chr 2:140,289,115...140,324,425

G

cadherin 1

disease_progression
susceptibility

protein:decreased expression:prostate gland
ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: PROSTATE CANCER, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Prostate cancer
DNA:polymorphism:promoter:-160C>A (human)

PMID:1722187 PMID:2403327 PMID:2449335 PMID:8075649 PMID:9537325 More...

RGD:2289487 RGD:2289493

NCBI chr 6:18,075,487...18,155,986
Ensembl chr 6:18,075,480...18,155,986

G

cadherin 13

disease_progression

DNA:hypermethylation:promoter

NCBI chr 6:4,809,752...5,832,188
Ensembl chr 6:4,808,255...5,832,415

G

cadherin 3

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr 6:18,190,971...18,236,184
Ensembl chr 6:18,191,664...18,235,862

G

cyclin dependent kinase 13

mRNA,protein:increased expression:prostate:

NCBI chr18:54,310,311...54,430,060
Ensembl chr18:54,312,479...54,430,786

G

cyclin dependent kinase 2

NCBI chr 5:21,365,723...21,372,170
Ensembl chr 5:21,365,764...21,372,168

G

cyclin dependent kinase 4

NCBI chr 5:23,039,206...23,041,959
Ensembl chr 5:23,038,891...23,042,061

G

cyclin dependent kinase inhibitor 1A

NCBI chr 7:32,354,776...32,363,771
Ensembl chr 7:32,354,672...32,363,761

G

cyclin dependent kinase inhibitor 2A

disease_progression

protein:increased expression:prostate gland
DNA:hypermethylation:promoter

PMID:16483154 PMID:16799475

RGD:2289684 RGD:2289685

NCBI chr 1:200,774,496...200,799,149
Ensembl chr 1:200,792,469...200,798,854

G

CDKN2A interacting protein

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:44,885,603...44,890,504
Ensembl chr15:44,886,692...44,892,246

G

cyclin dependent kinase inhibitor 2B

disease_progression

protein:increased expression:prostate gland

NCBI chr 1:200,666,250...200,770,880
Ensembl chr 1:200,761,004...200,766,056

G

ceramide synthase 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:139,027,604...139,154,830
Ensembl chr 1:139,030,642...139,136,874

G

cilia and flagella associated protein 43

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:115,073,529...115,201,965
Ensembl chr14:115,073,366...115,174,043

G

cilia and flagella associated protein 65

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:121,026,365...121,067,224
Ensembl chr15:121,026,245...121,062,738

G

ChaC glutathione specific gamma-glutamylcyclotransferase 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:130,360,510...130,363,332
Ensembl chr 1:130,360,514...130,363,308

G

chromatin assembly factor 1 subunit B

disease_progression

protein:increased expression:prostate:
ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:19309489 PMID:23265383

NCBI chr13:200,048,096...200,074,902
Ensembl chr13:200,048,149...200,072,556

G

chromodomain helicase DNA binding protein 1

DNA:deletions: :

NCBI chr 2:105,113,149...105,205,303
Ensembl chr 2:105,113,668...105,203,119

G

chromodomain helicase DNA binding protein 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:85,980,759...86,107,886
Ensembl chr 7:85,983,837...86,106,938

G

checkpoint kinase 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:52,759,224...52,790,878
Ensembl chr 9:52,753,528...52,790,700

G

checkpoint kinase 2

susceptibility

ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: Prostate cancer | ClinVar Annotator: match by term: Prostate cancer, susceptibility to
DNA:mutations: :multiple

OMIM
ClinVar
RGD

PMID:3313277 PMID:9536098 PMID:10617473 PMID:11053450 PMID:11298456 More...

NCBI chr14:45,699,833...45,967,350
Ensembl chr14:45,929,715...45,967,290

G

chromogranin A

susceptibility

DNA:missense mutation:cds:p.E264D (human)

NCBI chr 7:114,345,542...114,357,799
Ensembl chr 7:114,345,305...114,358,075

G

chromogranin B

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:14,747,282...14,761,995
Ensembl chr17:14,746,997...14,761,995

G

cysteine rich hydrophobic domain 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:59,176,650...59,230,332
Ensembl chr X:59,176,604...59,230,783

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component of inhibitor of nuclear factor kappa B kinase complex

protein:increased serine phosphorylation:prostate gland

NCBI chr14:111,316,178...111,351,669
Ensembl chr14:111,315,141...111,351,868

G

cytoskeleton associated protein 5

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:15,680,723...15,790,580
Ensembl chr 2:15,680,787...15,790,569

G

CLPTM1 like

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:79,237,000...79,248,503
Ensembl chr16:79,237,061...79,248,500

G

cyclic nucleotide gated channel subunit alpha 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:37,896,460...37,968,935
Ensembl chr 8:37,896,459...37,969,344

G

ciliary neurotrophic factor receptor

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:32,211,809...32,251,412
Ensembl chr10:32,211,777...32,251,503

G

component of oligomeric golgi complex 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:7,745,928...7,760,539
Ensembl chr12:7,743,274...7,760,504

G

collagen type I alpha 1 chain

ClinVar Annotator: match by term: Prostate cancer

PMID:17211858 PMID:23265383 PMID:25741868 PMID:28492532

NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,004

G

collagen type XXIV alpha 1 chain

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:129,911,760...130,243,177
Ensembl chr 4:129,905,327...130,242,358

G

collagen type V alpha 1 chain

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:273,934,219...274,083,264
Ensembl chr 1:273,971,971...274,085,111

G

catechol-O-methyltransferase

susceptibility
disease_progression
no_association

DNA:polymorphism:cds
DNA:polymorphism: :p.V158M

PMID:16126332 PMID:16492910 PMID:17507624

RGD:2289718 RGD:2289719 RGD:2289720

NCBI chr14:51,384,729...51,403,997
Ensembl chr14:51,385,738...51,403,998

G

COP9 signalosome subunit 6

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:8,002,702...8,005,545
Ensembl chr 3:7,982,892...8,005,633

G

corin, serine peptidase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:37,530,812...37,811,226
Ensembl chr 8:37,530,815...37,809,761

G

carboxypeptidase A6

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:67,157,341...67,411,582
Ensembl chr 4:67,158,318...67,411,593

G

cleavage and polyadenylation specific factor 7

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:10,087,581...10,112,929
Ensembl chr 2:10,087,632...10,115,076

G

CREB regulated transcription coactivator 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:53,146,317...53,255,985
Ensembl chr 7:53,146,404...53,255,977

G

cone-rod homeobox

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:53,506,410...53,509,858
Ensembl chr 6:53,506,410...53,512,190

G

CUB and Sushi multiple domains 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:89,778,338...90,424,979

G

catenin alpha 1

disease_progression

protein:decreased expression:prostate gland

PMID:16334164 PMID:17639504

RGD:2289791 RGD:2289793

NCBI chr 2:140,682,776...140,869,828
Ensembl chr 2:140,682,371...140,871,334

G

catenin beta 1

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:9927029 PMID:23265383

NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,164,277...25,208,311

G

cortactin binding protein 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr18:28,130,213...28,573,166
Ensembl chr18:28,415,067...28,573,159

G

C-X-C motif chemokine ligand 12

ameliorates

human cells in mouse model

NCBI chr14:91,516,383...91,543,857
Ensembl chr14:91,516,431...91,552,752

G

C-X-C motif chemokine receptor 4

ameliorates

human cells in mouse model

NCBI chr15:15,663,652...15,666,706
Ensembl chr15:15,663,494...15,667,232

G

cytochrome P450 family 17 subfamily A member 1

NCBI chr14:113,805,616...113,820,445
Ensembl chr14:113,805,611...113,812,041

G

cytochrome P450 family 1 subfamily A member 1

NCBI chr 7:58,802,887...58,809,155
Ensembl chr 7:58,802,887...58,809,775

G

cysteinyl leukotriene receptor 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:62,380,778...62,407,736
Ensembl chr X:62,380,780...62,456,689

G

DAB2 interacting protein

treatment

human cells in mouse model

NCBI chr 1:261,732,280...261,859,833
Ensembl chr 1:261,659,785...261,859,830

G

death domain associated protein

disease_progression

NCBI chr 7:29,676,854...29,681,145
Ensembl chr 7:29,676,856...29,681,110

G

dachsous cadherin-related 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:74,664,505...74,936,954
Ensembl chr 8:74,664,598...74,934,835

G

DExD-box helicase 50

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:71,989,137...72,030,996
Ensembl chr14:71,989,584...72,030,980

G

DExD/H-box helicase 60

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:21,077,491...21,163,563
Ensembl chr14:21,083,350...21,163,561

G

DEAF1 transcription factor

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr 2:404,514...427,584
Ensembl chr 2:404,533...427,542

G

diacylglycerol O-acyltransferase 2 like 6

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:56,212,494...56,239,641
Ensembl chr X:56,216,066...56,239,196

G

DiGeorge syndrome critical region gene 6 like

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:51,644,840...51,657,368

G

dihydrodiol dehydrogenase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:54,210,693...54,217,250
Ensembl chr 6:54,210,609...54,217,285

G

DExH-box helicase 29

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:34,426,647...34,478,233
Ensembl chr16:34,425,708...34,478,177

G

DIS3 like exosome 3'-5' exoribonuclease

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:164,310,120...164,352,182
Ensembl chr 1:164,310,448...164,353,537

G

dihydrolipoamide S-acetyltransferase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:39,738,639...39,763,813
Ensembl chr 9:39,738,564...39,796,806

G

delta like canonical Notch ligand 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:198,815...211,346
Ensembl chr 1:199,358...211,346

G

dynein axonemal heavy chain 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:24,911,160...25,127,017
Ensembl chr 3:24,920,284...25,126,092

G

dynein axonemal heavy chain 8

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:34,197,185...34,479,640
Ensembl chr 7:34,188,145...34,479,623

G

dynein axonemal heavy chain 9

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:56,045,079...56,366,327
Ensembl chr12:56,045,381...56,358,236

G

DnaJ heat shock protein family (Hsp40) member C3

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:25466870 PMID:28940199

NCBI chr11:65,230,145...65,299,084
Ensembl chr11:65,230,162...65,303,834

G

DnaJ heat shock protein family (Hsp40) member C6

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:22563501 PMID:23211418 PMID:26528954 PMID:28492532

NCBI chr 6:146,990,115...147,161,010
Ensembl chr 6:146,989,351...147,155,131

G

DNA methyltransferase 1

disease_progression

protein:increased expression:nucleus:

NCBI chr 2:68,981,564...69,040,364
Ensembl chr 2:68,981,566...69,029,844

G

dedicator of cytokinesis 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:53,843,248...54,248,708
Ensembl chr16:53,843,252...54,248,638

G

dedicator of cytokinesis 5

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:9,197,280...9,438,715
Ensembl chr14:9,197,293...9,436,249

G

diphthamide biosynthesis 7

ClinVar Annotator: match by term: Malignant tumor of prostate

G

developmental pluripotency associated 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:150,165,485...150,176,712
Ensembl chr13:150,165,462...150,176,761

G

dihydropyrimidine dehydrogenase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:119,931,471...120,712,461
Ensembl chr 4:119,931,414...120,712,459

G

DS cell adhesion molecule like 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:44,785,142...45,153,256
Ensembl chr 9:44,785,701...45,147,140

G

dual specificity phosphatase 1

disease_progression

NCBI chr16:51,457,924...51,461,095
Ensembl chr16:51,458,020...51,461,086

G

dymeclin

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:98,642,506...99,024,664
Ensembl chr 1:98,638,339...99,024,642

G

E2F transcription factor 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:37,178,587...37,190,118
Ensembl chr17:37,178,599...37,189,883

G

E2F transcription factor 3

disease_progression

PMID:15184867 PMID:17701752 PMID:25017995

RGD:13504717 RGD:13504729 RGD:13504730

NCBI chr 7:15,793,519...15,870,213
Ensembl chr 7:15,794,178...15,870,204

G

E2F transcription factor 5

mRNA,protein:increased expression:prostate:

NCBI chr 4:51,478,399...51,512,617
Ensembl chr 4:51,478,050...51,512,718

G

ELL associated factor 2

protein:decreased expression:prostate gland

NCBI chr13:138,632,541...138,681,607
Ensembl chr13:138,648,270...138,681,613

G

eukaryotic translation elongation factor 2

protein:increased expression:prostate (human)

NCBI chr 2:74,746,541...74,756,687
Ensembl chr 2:74,747,080...74,756,680

G

EF-hand calcium binding domain 6

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:5,166,994...5,408,130

G

epidermal growth factor receptor

NCBI chr 9:139,302,410...139,474,632
Ensembl chr 9:139,300,022...139,475,589

G

eukaryotic translation initiation factor 3 subunit H

disease_progression

DNA:amplification
mRNA:increased expression:prostate gland

PMID:10362802 PMID:11733359

RGD:2289901 RGD:2289902

NCBI chr 4:21,955,026...22,053,683
Ensembl chr 4:21,954,874...22,058,699

G

eukaryotic translation initiation factor 4 gamma 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:79,022,222...79,382,062
Ensembl chr 6:79,022,138...79,382,029

G

elastin microfibril interfacer 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:112,031,910...112,039,928
Ensembl chr 3:112,031,917...112,046,429

G

endoglin

severity

protein:increased expression:tumor, vasculature (human)

NCBI chr 1:268,309,379...268,343,861
Ensembl chr 1:268,309,400...268,343,783

G

enolase 2

NCBI chr 5:63,799,927...63,809,067
Ensembl chr 5:63,799,930...63,809,410

G

ecto-NOX disulfide-thiol exchanger 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:23,234,764...23,894,763
Ensembl chr11:23,237,775...23,894,699

G

ectonucleotide pyrophosphatase/phosphodiesterase 7

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:2,612,543...2,619,541
Ensembl chr12:2,612,574...2,619,519

G

ectonucleoside triphosphate diphosphohydrolase 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:24,623,579...24,659,642
Ensembl chr13:24,624,417...24,659,639

G

endosomal transmembrane epsin interactor 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:222,658,488...222,725,262
Ensembl chr 1:222,658,382...222,725,259

G

E1A binding protein p300

disease_progression

NCBI chr 5:7,311,165...7,394,515
Ensembl chr 5:7,311,171...7,393,760

G

EPH receptor B1

susceptibility

DNA:SNPs,haplptype:multiple

NCBI chr13:75,904,678...76,351,540
Ensembl chr13:75,905,676...76,345,534

G

epithelial stromal interaction 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:24,116,991...24,216,219
Ensembl chr11:24,116,986...24,216,215

G

erb-b2 receptor tyrosine kinase 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:22,591,621...22,621,384
Ensembl chr12:22,590,725...22,621,351

G

erb-b2 receptor tyrosine kinase 3

disease_progression

protein:altered localization:nucleus
ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:17532856 PMID:23265383

NCBI chr 5:21,474,218...21,495,040
Ensembl chr 5:21,474,475...21,495,038

G

erb-b2 receptor tyrosine kinase 4

protein:increased expression:prostate gland

NCBI chr15:113,966,573...115,096,984
Ensembl chr15:113,974,437...115,096,565

G

erbb2 interacting protein

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:44,415,106...44,533,353
Ensembl chr16:44,415,189...44,533,349

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ERCC excision repair 2, TFIIH core complex helicase subunit

susceptibility

DNA:missense mutation:cds:p.D312N (human)
DNA:polymorphism:exon:p.R156R(human)

PMID:17695467 PMID:24649009

RGD:5688739 RGD:8657136

NCBI chr 6:51,734,318...51,757,508
Ensembl chr 6:51,734,320...51,757,553

G

estrogen receptor 1

susceptibility
severity
disease_progression

DNA:repeat
DNA:hypermethylation:promoter
mRNA:increased expression:prostate gland

PMID:17908481 PMID:17922863 PMID:18006911

RGD:2290020 RGD:2290022 RGD:2290023

NCBI chr 1:14,217,032...14,604,906
Ensembl chr 1:14,217,036...14,493,363

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estrogen receptor 2

susceptibility

DNA:snps, haplotype:multiple (human)

NCBI chr 1:193,823,666...193,907,330
Ensembl chr 1:193,829,560...193,906,565

G

exocyst complex component 2

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:25741868

NCBI chr 7:195,079...341,470
Ensembl chr 7:195,083...341,442

G

EYA transcriptional coactivator and phosphatase 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:63,970,939...64,328,107
Ensembl chr 4:63,970,807...64,328,105

G

enhancer of zeste 2 polycomb repressive complex 2 subunit

severity

protein:increased expression:prostate gland (human)

NCBI chr 9:109,384,976...109,450,943
Ensembl chr 9:109,385,015...109,450,941

G

coagulation factor II, thrombin

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,455...15,819,137

G

coagulation factor V

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:81,403,273...81,484,908
Ensembl chr 4:81,403,274...81,485,066

G

fatty acid binding protein 5

mRNA:increased expression:prostate (human)

NCBI chr 4:55,277,831...55,282,585
Ensembl chr 4:55,275,205...55,282,908

G

family with sequence similarity 13 member C

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:62,622,895...62,754,404
Ensembl chr14:62,565,138...62,925,849

G

family with sequence similarity 83 member C

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:38,644,985...38,653,323
Ensembl chr17:38,645,441...38,652,083

G

FA complementation group A

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:10094191 PMID:24728327 PMID:25741868 PMID:26181256 PMID:28492532 More...

NCBI chr 6:253,207...300,159
Ensembl chr 6:253,207...300,152

G

Fas cell surface death receptor

severity
disease_progression

DNA:polymorphism

PMID:17667965 PMID:18237448

RGD:2289639 RGD:2290050

NCBI chr14:100,927,305...100,954,781
Ensembl chr14:100,927,089...100,956,716

G

F-box DNA helicase 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:65,060,714...65,108,975
Ensembl chr10:65,060,312...65,108,379

G

fibrillin 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:131,150,665...131,370,241
Ensembl chr 2:131,150,667...131,370,466

G

F-box and leucine rich repeat protein 5

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:10,915,526...10,987,374
Ensembl chr 8:10,913,106...10,961,306

G

FYVE, RhoGEF and PH domain containing 1

protein:increased expression:prostate gland (human)

NCBI chr X:47,191,838...47,231,656
Ensembl chr X:47,192,427...47,231,342

G

FYVE, RhoGEF and PH domain containing 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:32,648,260...32,674,539
Ensembl chr 7:32,648,222...32,674,529

G

fibroblast growth factor 7

mRNA:increased expression:prostate gland stroma, hormone insensitive tumors

NCBI chr 1:122,215,878...122,278,705
Ensembl chr 1:122,215,882...122,277,750

G

fibroblast growth factor receptor 1

disease_progression

NCBI chr15:48,053,895...48,106,634
Ensembl chr15:48,053,340...48,106,724

G

fibroblast growth factor receptor 2

disease_progression
no_association

mRNA:decreased expression:prostate:isoforms IIIb and IIIc, decrease in IIIb associated with progression to androgen-independence
mRNA:splice variant::shift from Fgfr2IIIb to Fgfr2IIIc in malignancy, restoration of Fgfr2IIIb slows growth
mRNA:alternative form:prostate:switch from isoform IIIb to IIIc
mRNA:increased expression:prostate gland
DNA:mutation,polymorphism:exons:no mutations or polymorphisms found in patient or cell line DNA to explain changes in expression seen in other studies

PMID:9285567 PMID:9537256 PMID:11069376 PMID:11170144 PMID:12111699

RGD:2289086 RGD:2289728 RGD:2289746 RGD:2289845 RGD:2289859

NCBI chr14:131,183,095...131,285,001
Ensembl chr14:131,181,713...131,289,425

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fibroblast growth factor receptor 4

disease_progression

DNA:SNP:exon 9: 288G>A, p.G388R (human)

NCBI chr 2:80,841,536...80,853,791
Ensembl chr 2:80,841,536...80,853,796

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FHF complex subunit HOOK interacting protein 1B

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:3,441,613...3,464,237
Ensembl chr 9:3,446,075...3,464,226

G

fragile histidine triad diadenosine triphosphatase

DNA:hypermethylation:promoter:methylation percentage 15% in tumors vs no methylation in nonmalignant prostate
DNA:SNP:intron:increased risk in carriers of minor allele of SNP rs760317
DNA:SNP:intron:reduced risk in carriers of minor allele of SNP rs760317

PMID:11839671 PMID:15705877 PMID:17548701

RGD:2289869 RGD:2289878 RGD:2289896

NCBI chr13:41,443,963...42,884,799
Ensembl chr13:41,443,965...42,392,817

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fms related receptor tyrosine kinase 3

NCBI chr11:5,370,475...5,455,439
Ensembl chr11:5,370,496...5,455,358

G

forkhead box O1

disease_progression

mRNA:decreased expression:tumor:lower in high versus low Gleason score tumors, also lower in tumor vs adjacent normal tissue (p<0.05 compared to at least one housekeeping gene)

NCBI chr11:15,317,222...15,410,059
Ensembl chr11:15,317,124...15,410,473

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forkhead box O3

mRNA:decreased expression:tumor:lower in tumor vs adjacent normal tissue (p<0.05 compared to at least one housekeeping gene)

NCBI chr 1:74,626,673...74,760,323
Ensembl chr 1:74,628,218...74,760,325

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FRAS1 related extracellular matrix 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:13,775,267...14,116,377
Ensembl chr11:13,959,666...14,113,230

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gamma-aminobutyric acid type A receptor subunit beta2

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:25741868 PMID:28492532

NCBI chr16:61,984,923...62,240,902
Ensembl chr16:61,984,925...62,239,937

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gamma-aminobutyric acid type A receptor subunit gamma1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:36,198,056...36,262,492
Ensembl chr 8:36,198,060...36,262,430

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glyceraldehyde-3-phosphate dehydrogenase, spermatogenic

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:44,968,965...44,978,992
Ensembl chr 6:44,969,139...44,979,166

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growth differentiation factor 10

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:88,522,956...88,534,719
Ensembl chr14:88,522,948...88,534,709

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GEN1 Holliday junction 5' flap endonuclease

ClinVar Annotator: match by term: GEN1-related condition | ClinVar Annotator: match by term: GEN1-related prostate cancer

PMID:25741868 PMID:28492532

NCBI chr 3:120,067,792...120,097,305
Ensembl chr 3:120,065,973...120,097,056

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guided entry of tail-anchored proteins factor 3, ATPase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:66,251,381...66,261,135
Ensembl chr 2:66,251,432...66,260,958

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GDNF family receptor alpha 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:140,263,297...140,283,227
Ensembl chr 2:140,263,301...140,283,066

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GLI family zinc finger 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:22,736,325...22,747,421
Ensembl chr 5:22,739,900...22,747,421

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G protein subunit gamma transducin 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:73,403,647...73,717,746
Ensembl chr 9:73,403,740...73,719,161

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glyceronephosphate O-acyltransferase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:59,203,519...59,240,303
Ensembl chr14:59,203,090...59,241,247

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golgi membrane protein 1

protein,mRNA:increased expression:prostate

NCBI chr10:29,117,578...29,219,024
Ensembl chr10:29,118,314...29,219,018

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gephyrin

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:90,345,726...90,913,625
Ensembl chr 7:90,346,714...90,916,455

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G protein-coupled receptor 26

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:133,174,553...133,202,901
Ensembl chr14:133,174,633...133,196,805

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G protein-coupled receptor 55

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:131,655,655...131,674,816
Ensembl chr15:131,655,663...131,673,693

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G protein-coupled receptor 82

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:37,328,672...37,334,144
Ensembl chr X:37,328,678...37,334,984

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growth factor receptor bound protein 2

treatment
disease_progression

DNA:amplification, mutation

PMID:17372910 PMID:28930697

RGD:13504750 RGD:13504751

NCBI chr12:5,940,723...6,009,095
Ensembl chr12:5,940,647...6,010,835

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glutamate ionotropic receptor delta type subunit 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:86,539,896...87,227,089
Ensembl chr14:86,539,916...87,227,133

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glutamate ionotropic receptor NMDA type subunit 1

ClinVar Annotator: match by term: Malignant tumor of prostate

G

glutamate metabotropic receptor 8

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr18:20,945,049...21,756,952
Ensembl chr18:20,951,003...21,758,568

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gastrin releasing peptide

protein:increased expression:serum (human)

NCBI chr 1:161,708,815...161,721,986
Ensembl chr 1:161,708,812...161,721,782

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glutamate rich WD repeat containing 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:53,849,673...53,856,229
Ensembl chr 6:53,849,852...53,859,385

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glucuronidase beta

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:16,672,071...16,686,520
Ensembl chr 3:16,671,389...16,689,203

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heme binding protein 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:26,001,650...26,011,381

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HEPACAM family member 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:73,020,279...73,074,872
Ensembl chr 9:73,020,281...73,067,520

G

HHIP like 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:120,627,491...120,655,484

G

hypoxia inducible factor 1 subunit alpha

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845

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homeodomain interacting protein kinase 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:48,666,726...48,672,977
Ensembl chr 6:48,666,728...48,674,346

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histone cell cycle regulator

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:51,029,117...51,102,409
Ensembl chr14:51,029,126...51,102,409

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HLF transcription factor, PAR bZIP family member

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:31,589,337...31,643,595
Ensembl chr12:31,589,337...31,643,594

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hemicentin 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:126,850,208...127,342,696
Ensembl chr 9:126,850,313...127,342,685

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heterogeneous nuclear ribonucleoprotein K

protein:increased expression:prostate gland (human)

NCBI chr10:30,975,639...30,987,955
Ensembl chr10:30,975,702...30,987,956

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homeobox B13

ClinVar Annotator: match by term: PROSTATE CANCER, SUSCEPTIBILITY TO

PMID:8756292 PMID:15964834 PMID:17138648 PMID:22236224 PMID:22714738 More...

NCBI chr12:24,948,307...24,950,661
Ensembl chr12:24,947,687...24,950,714

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HPS3 biogenesis of lysosomal organelles complex 2 subunit 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:89,360,829...89,409,502
Ensembl chr13:89,360,874...89,410,525

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5-hydroxytryptamine receptor 2C

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:94,053,415...94,313,352
Ensembl chr X:94,053,456...94,313,355

G

5-hydroxytryptamine receptor 5A

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr18:3,029,681...3,033,646

G

HtrA serine peptidase 2

mRNA, protein:increased expression:prostate (human)

NCBI chr 3:68,516,666...68,520,025
Ensembl chr 3:68,516,500...68,519,886

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inhibitor of Bruton tyrosine kinase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:83,973,541...84,070,751
Ensembl chr 1:83,973,582...84,070,554

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intercellular adhesion molecule 1

NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205

G

interferon induced with helicase C domain 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:68,930,998...68,985,145
Ensembl chr15:68,928,254...68,985,083

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intraflagellar transport 43

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:99,155,889...99,254,436
Ensembl chr 7:99,158,892...99,254,355

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insulin like growth factor 1 receptor

disease_progression

NCBI chr 1:137,383,623...137,691,038
Ensembl chr 1:137,387,825...137,691,058

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insulin like growth factor 2 receptor

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:7,369,485...7,472,480
Ensembl chr 1:7,368,103...7,472,548

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insulin like growth factor binding protein 3

no_association
severity

DNA:SNP:promoter:rs2854744, homozygous C allele associated with 2x increased risk
DNA:SNP:promoter:no association with rs2854744, 440 cases and 480 related controls from Cleveland, OH and Detroit, MI
DNA:SNP:promoter:rs2854744 C allele associated with low grade tumors only, odds ratio=4.1 for low grade vs 1.0 for high grade

PMID:15006930 PMID:17668637 PMID:17724372

RGD:2290008 RGD:2290012 RGD:2290015

NCBI chr18:50,002,921...50,009,425
Ensembl chr18:50,003,022...50,010,690

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inhibitor of nuclear factor kappa B kinase subunit beta

protein:increased serine phosphorylation:prostate gland

NCBI chr17:11,289,607...11,348,557
Ensembl chr17:11,289,690...11,348,549

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interleukin 16

DNA:SNP:exon:rs4072111 (human)

NCBI chr 7:49,973,937...50,102,346
Ensembl chr 7:49,973,938...50,102,346

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interleukin 33

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:215,899,830...215,941,944
Ensembl chr 1:215,899,436...215,941,840

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integrin linked kinase

disease_progression

protein:decreased expression:tumor:significantly lower in benign prostatic hyperplasia then any prostate cancer (p<0.01), gradient of expression from BPH to poorly differentiated C+D stage neoplasms
mRNA:decreased expression:tumor:lower in high versus low Gleason score tumors (p<0.05 compared to at least one housekeeping gene)

PMID:15704679 PMID:18336616

RGD:2301729 RGD:2301731

NCBI chr 9:3,145,647...3,152,097
Ensembl chr 9:3,145,608...3,159,858

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interphotoreceptor matrix proteoglycan 2

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:25741868

NCBI chr13:157,672,973...157,763,817
Ensembl chr13:157,675,265...157,759,266

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inhibitor of growth family member 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:64,027,789...64,036,671
Ensembl chr 5:64,027,855...64,036,773

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inhibin subunit alpha

mRNA,protein:decreased expression:malignant tumors

NCBI chr15:121,581,847...121,586,020
Ensembl chr15:121,580,803...121,586,006

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indolethylamine N-methyltransferase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr18:42,213,335...42,218,175
Ensembl chr18:42,209,352...42,218,174

G

insulin

disease_progression

NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841

G

integrator complex subunit 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:95,904,072...95,944,805
Ensembl chr 4:95,905,150...95,944,809

G

integrator complex subunit 8

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:41,820,718...41,878,857
Ensembl chr 4:41,821,768...41,878,690

G

immunity related GTPase Q

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:50,433,858...50,442,106
Ensembl chr 6:50,433,862...50,445,575

G

integrin subunit alpha D

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:17,136,161...17,169,776
Ensembl chr 3:17,136,177...17,169,667

G

integrin subunit beta 6

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:67,041,516...67,175,409
Ensembl chr15:67,041,522...67,175,234

G

inter-alpha-trypsin inhibitor heavy chain 5

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:63,688,416...63,764,566
Ensembl chr10:63,688,427...63,767,118

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ITPRIP like 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:46,897,131...46,901,845
Ensembl chr 3:46,897,137...46,900,483

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Janus kinase 1

severity

DNA:frameshift mutations

NCBI chr 6:147,320,288...147,567,188
Ensembl chr 6:147,429,056...147,567,182

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junction plakoglobin

severity

DNA,mRNA,protein:loss of heterozygosity, decreased expression:tumor:relative to either BPH or normal prostate
protein:increased expression:tumor:significantly associated with capsular invasion (p=0.007 for all cases, p=0.015 for cases with Gleason score 5-7)

PMID:10206308 PMID:15781623

RGD:2291864 RGD:2291876

NCBI chr12:20,902,395...20,931,208
Ensembl chr12:20,901,396...20,931,210

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lysine acetyltransferase 7

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:25,970,966...26,005,006
Ensembl chr12:25,970,962...26,008,302

G

katanin catalytic subunit A1 like 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:96,566,852...96,676,184
Ensembl chr 1:96,566,848...96,676,519

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potassium voltage-gated channel modifier subfamily F member 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:125,664,027...125,666,054
Ensembl chr 3:125,664,365...125,666,656

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potassium inwardly rectifying channel subfamily J member 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:55,779,020...55,812,761
Ensembl chr 9:55,780,257...55,781,375

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potassium inwardly rectifying channel subfamily J member 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:9,526,399...9,549,290
Ensembl chr 5:9,547,177...9,548,520

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potassium calcium-activated channel subfamily N member 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:94,913,631...95,112,845
Ensembl chr 4:94,915,965...95,113,275

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potassium voltage-gated channel subfamily Q member 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:8,669,969...8,978,656
Ensembl chr 4:8,669,121...8,970,342

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potassium voltage-gated channel subfamily Q member 5

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr 1:52,435,332...52,939,705
Ensembl chr 1:52,435,235...52,939,823

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lysine demethylase 3A

mRNA:increased expression:prostate gland (human)
mRNA:increased expression:prostate (human)

PMID:20127736 PMID:22120715

RGD:9586733 RGD:9587486

NCBI chr 3:58,300,109...58,355,000
Ensembl chr 3:58,302,949...58,354,945

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lysine demethylase 4A

mRNA:increased expression:prostate (human)

NCBI chr 6:167,597,954...167,642,381
Ensembl chr 6:167,597,956...167,642,333

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lysine demethylase 4B

mRNA:increased expression:prostate (human)

NCBI chr 2:73,746,379...73,889,881
Ensembl chr 2:73,747,669...73,889,866

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lysine demethylase 4C

severity

mRNA:increased expression:prostate gland (human)

NCBI chr 1:215,071,335...215,507,778
Ensembl chr 1:215,071,419...215,507,800

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lysine demethylase 5A

mRNA:decreased expression:prostate gland (human)

NCBI chr 5:67,628,791...67,716,143
Ensembl chr 5:67,629,380...67,715,905

G

lysine demethylase 5B

severity

mRNA:increased expression:prostate gland (human)

NCBI chr10:24,739,115...24,831,537
Ensembl chr10:24,736,838...24,831,447

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lysine demethylase 6A

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:39,953,764...40,154,197
Ensembl chr X:39,953,814...40,154,029

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kinase insert domain receptor

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:41,809,116...41,856,379
Ensembl chr 8:41,809,122...41,856,336

G

KIAA0100

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:44,853,838...44,893,468
Ensembl chr12:44,859,938...44,893,430

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KIAA1755

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:41,275,501...41,321,328
Ensembl chr17:41,275,505...41,329,143

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kinesin family member 12

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:254,711,820...254,720,559
Ensembl chr 1:254,711,823...254,719,615

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kinesin family member 16B

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:24,882,139...25,188,990
Ensembl chr17:24,882,142...25,186,703

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kinesin family member 5A

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr 5:22,813,617...22,851,976
Ensembl chr 5:22,816,854...22,851,973

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KLF transcription factor 6

NCBI chr10:66,488,445...66,497,830
Ensembl chr10:66,488,391...66,497,844

G

kelch like family member 20

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:116,005,562...116,083,478
Ensembl chr 9:116,005,574...116,083,452

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kallikrein related peptidase 10

susceptibility

DNA:SNP:exon:p.A50S (human)

NCBI chr 6:55,673,508...55,677,725
Ensembl chr 6:55,673,439...55,677,725

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kallikrein related peptidase 13

protein:decreased expression:prostate

NCBI chr 6:55,703,414...55,712,976
Ensembl chr 6:55,703,392...55,713,532

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kallikrein related peptidase 4

protein:increased expression:prostate gland

PMID:12370833 PMID:17545602

RGD:2314854 RGD:2314857

NCBI chr 6:55,589,997...55,617,514
Ensembl chr 6:55,589,999...55,594,294

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kallikrein related peptidase 6

protein:decreased expression:prostate

NCBI chr 6:55,629,983...55,639,215
Ensembl chr 6:55,629,991...55,638,080

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killin, p53 regulated DNA replication inhibitor

ClinVar Annotator: match by term: Prostate cancer

PMID:25741868 PMID:26467025 PMID:27535533

NCBI chr14:99,923,996...99,928,887

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lysine methyltransferase 2A

mRNA:decreased expression:prostate gland (human)

NCBI chr 9:45,743,566...45,828,559
Ensembl chr 9:45,743,397...45,824,884

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lysine methyltransferase 2B

mRNA:decreased expression:prostate gland (human)

NCBI chr 6:45,146,863...45,166,854
Ensembl chr 6:45,147,566...45,166,852

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lysine methyltransferase 2C

mRNA:decreased expression:prostate gland (human)

NCBI chr18:4,993,213...5,279,668
Ensembl chr18:4,993,227...5,278,723

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lysine methyltransferase 2D

mRNA:decreased expression:prostate gland (human)

NCBI chr 5:15,049,827...15,091,622

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lysine methyltransferase 2E (inactive)

mRNA:decreased expression:prostate gland (human)

NCBI chr 9:104,876,301...105,007,161
Ensembl chr 9:104,911,821...105,007,084

G

lysine methyltransferase 5A

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:29,523,102...29,543,522
Ensembl chr14:29,523,105...29,543,493

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kinetochore associated 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:30,154,918...30,241,988
Ensembl chr14:30,153,702...30,241,829

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keratinocyte proline rich protein

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:96,749,638...96,753,554

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KRAS proto-oncogene, GTPase

OMIM:176807 | OMIM:300147 | OMIM:300704 | OMIM:601518 | OMIM:602759 | OMIM:608656 | OMIM:608658 | OMIM:609299 | OMIM:609558 | OMIM:610321 | OMIM:610997 | OMIM:611100 | OMIM:611868 | OMIM:611928 | OMIM:611955 | OMIM:611958 | OMIM:611959

NCBI chr 5:48,508,774...48,546,260
Ensembl chr 5:48,508,811...48,549,358

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keratin 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:18,012,922...18,018,582
Ensembl chr 5:18,012,925...18,018,582

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keratin 33A

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:21,250,439...21,255,565

G

laminin subunit alpha 5

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:61,698,370...61,747,795
Ensembl chr17:61,697,517...61,747,955

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La ribonucleoprotein 1B

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:96,751,295...96,856,069
Ensembl chr 8:96,751,303...96,856,006

G

lymphoid enhancer binding factor 1

associated with prostate cancer

NCBI chr 8:113,824,511...113,944,078
Ensembl chr 8:113,825,161...113,944,070

G

DNA ligase 4

treatment

NCBI chr11:75,537,027...75,547,711
Ensembl chr11:75,537,036...75,547,716

G

lectin, mannose binding 1 like

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:58,717,159...58,730,752
Ensembl chr 7:58,717,821...58,730,172

G

leishmanolysin like peptidase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:134,596,116...134,656,751
Ensembl chr13:134,596,150...134,656,744

G

olfactory receptor 1S1-like

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:12,731,994...12,732,983

G

arylamine N-acetyltransferase 1

susceptibility

DNA:polymorphism

NCBI chr17:13,383,478...13,393,287

G

sialic acid-binding Ig-like lectin 5

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:55,781,438...55,791,954

G

zinc finger protein 84-like

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:25741868

NCBI chr 6:58,189,121...58,202,766

G

olfactory receptor 14A16-like

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:56,149,329...56,150,261

G

olfactory receptor 4C12-like

ClinVar Annotator: match by term: Malignant tumor of prostate

G

protocadherin beta-1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:142,741,845...142,747,621
Ensembl chr 2:142,741,682...142,747,760

G

serine/threonine-protein kinase Sgk3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:67,899,247...68,073,092
Ensembl chr 4:67,899,261...68,031,457

G

olfactory receptor 2T1-like

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:54,339,010...54,340,093

G

ligand-dependent corepressor

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:108,304,010...108,443,576
Ensembl chr14:108,304,048...108,436,982

G

olfactory receptor 2Z1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:70,637,292...70,638,221
Ensembl chr 2:70,637,292...70,638,221

G

olfactory receptor 8K3-like

ClinVar Annotator: match by term: Malignant tumor of prostate

G

glutathione S-transferase P-like

susceptibility

DNA:polymorphism:exon:p.I105V (human)

PMID:9111193 PMID:17067754

RGD:4142515 RGD:6906883

NCBI chr 2:5,005,498...5,009,247

G

protocadherin alpha-7

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:142,504,123...142,511,445

G

olfactory receptor 5AC1-like

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:161,404,131...161,405,380

G

matrix-remodeling-associated protein 5-like

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr Y:6,511,350...6,524,989

G

zinc finger protein 772-like

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:61,916,788...61,926,532

G

serpin B3-like

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:158,073,431...158,079,267

G

tripartite motif protein TRIM5

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:4,157,290...4,170,233
Ensembl chr 9:4,157,290...4,170,204

G

lon peptidase 2, peroxisomal

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:36,372,596...36,466,185
Ensembl chr 6:36,372,599...36,466,190

G

LDL receptor related protein 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:22,435,636...22,519,276

G

LDL receptor related protein 1B

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:9,612,805...11,499,969
Ensembl chr15:9,613,238...11,499,530

G

LDL receptor related protein 6

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:60,149,041...60,318,719
Ensembl chr 5:60,149,028...60,314,662

G

LDL receptor related protein associated protein 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:2,129,492...2,145,632
Ensembl chr 8:2,125,405...2,145,647

G

microtubule actin crosslinking factor 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:94,960,385...95,318,126
Ensembl chr 6:94,960,364...95,318,281

G

mitotic arrest deficient 1 like 1

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:11423979 PMID:25741868

NCBI chr 3:1,236,066...1,559,346
Ensembl chr 3:1,236,076...1,559,041

G

membrane associated guanylate kinase, WW and PDZ domain containing 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:100,846,693...102,171,199
Ensembl chr 9:100,847,013...102,170,004

G

MAM domain containing 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:223,541,491...223,547,723
Ensembl chr 1:223,384,827...223,548,420

G

mastermind like transcriptional coactivator 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:78,818,658...78,876,633
Ensembl chr 2:78,818,411...78,876,615

G

mastermind like domain containing 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:122,120,275...122,233,692
Ensembl chr X:122,120,300...122,234,472

G

mitogen-activated protein kinase kinase 5

protein:increased expression

NCBI chr 1:165,458,263...165,733,452
Ensembl chr 1:165,458,258...165,740,297

G

mitogen-activated protein kinase kinase 7

mRNA:splice variant:exon 2: (human)

NCBI chr 2:71,299,010...71,308,432
Ensembl chr 2:71,298,325...71,308,124

G

mitogen-activated protein kinase kinase kinase 7

DNA:deletion

NCBI chr 1:58,482,046...58,548,087
Ensembl chr 1:58,481,956...58,548,057

G

mitogen-activated protein kinase 10

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:132,445,818...132,751,575
Ensembl chr 8:132,298,299...132,776,820

G

mitogen-activated protein kinase 7

NCBI chr12:60,144,138...60,148,743
Ensembl chr12:60,144,136...60,158,739

G

microtubule associated protein tau

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:17,098,259...17,211,483
Ensembl chr12:17,095,587...17,211,373

G

MCC regulator of WNT signaling pathway

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:116,286,353...116,748,620
Ensembl chr 2:116,287,018...116,740,581

G

magnesium dependent phosphatase 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:75,087,443...75,088,944
Ensembl chr 7:75,087,468...75,089,227

G

mediator complex subunit 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:22,830,405...22,872,420
Ensembl chr12:22,841,205...22,872,409

G

microRNA mir-126

RNA:decreased expression:prostate gland

G

microRNA mir-152

disease_progression

miRNA:decreased expression:serum

NCBI chr12:24,292,249...24,292,328
Ensembl chr12:24,292,251...24,292,336

G

microRNA mir-155

severity

miRNA:increased expression:prostate gland

NCBI chr13:189,138,822...189,138,902
Ensembl chr13:189,138,822...189,138,902

G

microRNA mir-20a

NCBI chr11:60,735,109...60,735,179
Ensembl chr11:60,735,099...60,735,196

G

matrix metallopeptidase 13

disease_progression

protein:increased expression:plasma:higher concentration in patients with metastases vs non-metastatic PCa, BPH or control patients

NCBI chr 9:33,549,003...33,616,700
Ensembl chr 9:33,549,008...33,561,162

G

matrix metallopeptidase 15

disease_progression

NCBI chr 6:19,890,867...19,912,941
Ensembl chr 6:19,891,107...19,912,913

G

matrix metallopeptidase 2

disease_progression

protein:increased expression:prostate gland

NCBI chr 6:30,059,247...30,087,031
Ensembl chr 6:30,058,595...30,086,982

G

matrix metallopeptidase 7

NCBI chr 9:33,214,590...33,225,080
Ensembl chr 9:33,214,594...33,225,080

G

mitochondrial ribosomal protein L46

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:191,321,990...191,331,320
Ensembl chr 1:191,321,999...191,331,319

G

mutS homolog 2

disease_progression

NCBI chr 3:93,082,958...93,163,556
Ensembl chr 3:93,081,219...93,163,585

G

mutS homolog 6

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:25741868 PMID:28492532

NCBI chr 3:92,792,590...92,814,154
Ensembl chr 3:92,785,664...92,814,238

G

microseminoprotein beta

OMIM:176807 | OMIM:300147 | OMIM:300704 | OMIM:601518 | OMIM:602759 | OMIM:608656 | OMIM:608658 | OMIM:609299 | OMIM:609558 | OMIM:610321 | OMIM:610997 | OMIM:611100 | OMIM:611868 | OMIM:611928 | OMIM:611955 | OMIM:611958 | OMIM:611959

NCBI chr14:90,533,092...90,542,309
Ensembl chr14:90,533,103...90,582,765

G

macrophage scavenger receptor 1

susceptibility

DNA:SNPs
ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:12244320 PMID:12958598 PMID:17903305 PMID:21791690 PMID:24082139 More...

NCBI chr17:3,859,903...3,939,612
Ensembl chr17:3,859,692...3,939,726

G

MDM2 binding protein

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:18,533,201...18,608,702
Ensembl chr 4:18,532,041...18,608,602

G

methylenetetrahydrofolate reductase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,637...71,881,820

G

mitochondrial nucleoid associated protein 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:7,710,264...7,727,672
Ensembl chr12:7,710,279...7,725,080

G

mechanistic target of rapamycin kinase

treatment

NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888

G

mucin 1, cell surface associated

severity

NCBI chr 4:94,626,317...94,631,194

G

mucin 6, oligomeric mucus/gel-forming

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:630,075...657,967
Ensembl chr 2:629,796...655,380

G

MX dynamin like GTPase 1

susceptibility

DNA:SNP:promoter:-g.88G>T (rs2071430) (human)

NCBI chr13:204,843,049...204,868,927
Ensembl chr13:204,843,754...204,868,922

G

MAX interactor 1, dimerization protein

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:120,643,691...120,722,632
Ensembl chr14:120,643,830...120,724,099

G

MYC proto-oncogene, bHLH transcription factor

susceptibility
severity

DNA:snp:intron:IVS1-355T>A rs3891248 (human)
protein:increased expression:prostate gland (human)

PMID:18483343 PMID:20140016

RGD:7207432 RGD:7240541

NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,122...12,461,078

G

MYC binding protein 2

disease_progression

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:26408707

NCBI chr11:49,163,969...49,432,865
Ensembl chr11:49,163,684...49,432,583

G

myosin heavy chain 3

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:25741868 PMID:28492532 PMID:31030430

NCBI chr12:55,351,152...55,373,236
Ensembl chr12:55,347,087...55,375,353

G

myosin heavy chain 8

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:55,135,651...55,166,983
Ensembl chr12:55,134,844...55,167,748

G

myosin light chain kinase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:136,509,878...136,809,674
Ensembl chr13:136,509,755...136,809,668

G

myosin XVI

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:75,739,783...76,271,958

G

myosin IA

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:22,338,024...22,363,528
Ensembl chr 5:22,338,029...22,363,568

G

myosin VI

protein:increased expression:prostate gland epithelium, perinuclear region of cytoplasm

NCBI chr 1:89,992,860...90,137,767
Ensembl chr 1:89,992,866...90,137,734

G

myocardin

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:56,931,628...57,029,258
Ensembl chr12:56,931,317...57,029,258

G

myotilin

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:139,899,245...139,919,095
Ensembl chr 2:139,861,004...139,919,089

G

myelin regulatory factor

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:9,761,230...9,795,873

G

NSF attachment protein beta

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:30,361,439...30,396,105
Ensembl chr17:30,359,420...30,396,083

G

nibrin

susceptibility

DNA:deletion, loss of heterozygosity
ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: Prostate cancer

PMID:14973119 PMID:23265383 PMID:23555315 PMID:25741868 PMID:26467025 More...

NCBI chr 4:46,787,664...46,854,331
Ensembl chr 4:46,787,691...46,874,603

G

nuclear receptor coactivator 1

disease_progression

NCBI chr 3:113,997,214...114,251,080
Ensembl chr 3:113,999,253...114,250,298

G

nuclear receptor coactivator 2

mRNA:increased expression:prostate (human)

NCBI chr 4:64,888,029...65,245,757
Ensembl chr 4:64,954,238...65,246,572

G

nuclear receptor coactivator 3

mRNA:increased expression:prostate (human)

NCBI chr17:49,528,275...49,660,471
Ensembl chr17:49,528,179...49,663,200

G

nuclear receptor coactivator 4

severity

protein:increased expression:prostate gland
mRNA:decreased expression:prostate gland

PMID:12368219 PMID:15166229

RGD:2293534 RGD:2293535

NCBI chr14:90,505,614...90,531,302
Ensembl chr14:90,505,110...90,531,118

G

NECAP endocytosis associated 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:75,527,071...75,543,187
Ensembl chr 6:75,527,108...75,546,843

G

NIMA related kinase 9

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:98,275,973...98,322,072
Ensembl chr 7:98,275,979...98,322,055

G

negative elongation factor complex member C/D

disease_progression

NCBI chr17:59,129,055...59,141,499
Ensembl chr17:59,129,076...59,141,499

G

neural EGFL like 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:37,809,080...38,754,520
Ensembl chr 2:37,809,008...38,754,525

G

neuropilin and tolloid like 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:37,443,534...37,506,589
Ensembl chr 6:37,443,699...37,505,736

G

nuclear factor kappa B subunit 1

treatment
susceptibility

DNA:SNPs, haplotype: :multiple
DNA:indel:promoter

PMID:26068031 PMID:26788504 PMID:28797847

RGD:11054182 RGD:11554936 RGD:13506729

NCBI chr 8:118,391,010...118,478,927
Ensembl chr 8:118,390,638...118,506,691

G

NFKB inhibitor alpha

disease_progression
no_association
susceptibility

protein:increased serine phosphorylation
ClinVar Annotator: match by term: Malignant tumor of prostate
DNA:SNPs: :rs2233406, rs3138053 (human)
DNA:polymorphism:3' UTR
DNA:SNPs:promoter:-826C>T, -881A>G (human)

PMID:23093296 PMID:26068031 PMID:26834482

RGD:11054182 RGD:13506766 RGD:13506767

NCBI chr 7:64,508,119...64,510,754
Ensembl chr 7:64,507,822...64,511,277

G

NHS actin remodeling regulator

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:13,854,950...14,209,085
Ensembl chr X:14,097,006...14,206,568

G

sodium/potassium transporting ATPase interacting 2

mRNA, protein:decreased expression:prostate

NCBI chr 1:38,014,252...39,040,215
Ensembl chr 1:38,014,255...39,040,605

G

NK3 homeobox 1

OMIM:176807 | OMIM:300147 | OMIM:300704 | OMIM:601518 | OMIM:602759 | OMIM:608656 | OMIM:608658 | OMIM:609299 | OMIM:609558 | OMIM:610321 | OMIM:610997 | OMIM:611100 | OMIM:611868 | OMIM:611928 | OMIM:611955 | OMIM:611958 | OMIM:611959

NCBI chr14:7,783,296...7,787,036
Ensembl chr14:7,783,323...7,787,033

G

NLR family pyrin domain containing 1

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr12:51,479,968...51,495,540

G

NLR family pyrin domain containing 7

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:19066229 PMID:21507883 PMID:24105752

NCBI chr 6:59,112,811...59,150,916

G

NMD3 ribosome export adaptor

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:100,924,685...100,992,009
Ensembl chr13:100,924,742...100,962,354

G

nitric oxide synthase 3

disease_progression

DNA:polymorphism:exon:p.E298D (human)

NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943

G

notch receptor 3

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:7732783 PMID:15364702 PMID:16328531 PMID:23265383 PMID:25033846 More...

NCBI chr 2:62,364,507...62,402,348
Ensembl chr 2:62,364,501...62,402,344

G

nuclear receptor subfamily 3 group C member 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:144,822,937...144,956,451
Ensembl chr 2:144,822,939...144,956,451

G

NRAS proto-oncogene, GTPase

disease_progression

NCBI chr 4:105,845,913...105,853,769
Ensembl chr 4:105,845,872...105,858,227

G

netrin 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:87,671,153...87,784,704
Ensembl chr 5:87,671,873...87,784,702

G

NACHT and WD repeat domain containing 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:60,800,064...60,906,536
Ensembl chr 2:60,800,438...60,906,046

G

8-oxoguanine DNA glycosylase

susceptibility

DNA:missense mutation:cds:p.S326C (human)
DNA:missense mutation:exon:p.S326C (1245C>G) (rs1052133) (human)

PMID:19914098 PMID:24649009

RGD:8657136 RGD:8657378

NCBI chr13:66,038,669...66,045,478

G

oncoprotein induced transcript 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:75,726,353...75,753,461
Ensembl chr14:75,726,364...75,754,331

G

Obg like ATPase 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:80,081,568...80,253,776
Ensembl chr15:80,078,924...80,253,741

G

olfactomedin like 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:106,566,978...106,571,086
Ensembl chr 4:106,563,450...106,569,771

G

OXA1L mitochondrial inner membrane protein

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:76,234,710...76,266,700
Ensembl chr 7:76,230,889...76,266,429

G

p21 (RAC1) activated kinase 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:47,869,604...47,914,185
Ensembl chr 6:47,869,577...47,914,182

G

PALM2-AKAP2 fusion

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:250,824,055...250,968,545
NCBI chr 1:250,984,658...251,190,244
Ensembl chr 1:250,680,942...251,190,244

G

par-3 family cell polarity regulator

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:56,968,100...57,600,515
Ensembl chr10:56,967,434...57,600,456

G

pecanex 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:94,445,001...94,618,476
Ensembl chr 7:94,445,270...94,614,213

G

phosphodiesterase 1C

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr18:40,818,316...41,410,555
Ensembl chr18:40,820,644...41,409,087

G

phosphodiesterase 3A

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:52,413,503...52,737,771
Ensembl chr 5:52,409,882...52,738,406

G

phosphodiesterase 6B

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:80,378...111,960
Ensembl chr 8:80,378...110,672

G

phosphodiesterase 7B

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:27,958,261...28,425,754
Ensembl chr 1:27,958,270...28,302,666

G

platelet derived growth factor receptor beta

NCBI chr 2:151,155,753...151,192,818
Ensembl chr 2:151,155,756...151,192,647

G

pyruvate dehydrogenase kinase 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:75,246,956...75,260,134
Ensembl chr 9:75,246,002...75,260,134

G

pyruvate dehydrogenase phosphatase catalytic subunit 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:27,565,423...27,572,868
Ensembl chr 6:27,565,450...27,575,455

G

3-phosphoinositide dependent protein kinase 1

treatment

NCBI chr 3:39,429,928...39,512,623
Ensembl chr 3:39,432,058...39,512,601

G

phosphatidylethanolamine binding protein 1

NCBI chr14:34,523,901...34,530,238

G

pyroglutamyl-peptidase I

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:59,448,110...59,485,809
Ensembl chr 2:59,451,150...59,485,818

G

PHD finger protein 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:42,988,607...43,078,811
Ensembl chr 3:42,988,636...43,078,808

G

PHD finger protein 8

mRNA:increased expression:prostate (human)

NCBI chr X:46,648,164...46,761,192
Ensembl chr X:46,648,168...46,759,239

G

PH domain and leucine rich repeat protein phosphatase 1

disease_progression

mRNA:decreased expression:tumor:lower in high versus low Gleason score tumors (p<0.05 compared to at least one housekeeping gene)

NCBI chr 1:158,642,810...158,863,643
Ensembl chr 1:158,642,818...158,862,106

G

phosphatidylinositol glycan anchor biosynthesis class H

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:91,306,119...91,316,348
Ensembl chr 7:91,306,121...91,316,278

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

ClinVar Annotator: match by term: Prostate cancer

PMID:15520168 PMID:25741868

NCBI chr13:117,193,935...117,282,151
Ensembl chr13:117,180,544...117,274,587

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

treatment
disease_progression

PMID:18372911 PMID:20103642

RGD:13506809 RGD:13506810

NCBI chr13:79,427,033...79,610,840
Ensembl chr13:79,425,835...79,610,840

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:106,698,200...106,748,217
Ensembl chr 9:106,698,207...106,745,099

G

phosphoinositide-3-kinase regulatory subunit 1

disease_progression

mRNA:decreased expression:tumor:lower in high versus low Gleason score tumors (p<0.05 compared to at least one housekeeping gene)
ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:18336616 PMID:23265383

NCBI chr16:46,434,757...46,523,626
Ensembl chr16:46,511,521...46,523,609

G

phosphoinositide-3-kinase regulatory subunit 2

NCBI chr 2:59,637,363...59,652,075
Ensembl chr 2:59,637,371...59,652,073

G

paired like homeodomain 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:111,697,364...111,723,295
Ensembl chr 8:111,698,757...111,723,298

G

polycystin 2 like 1, transient receptor potential cation channel

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:111,398,704...111,434,584
Ensembl chr14:111,399,071...111,460,995

G

PKHD1 ciliary IPT domain containing fibrocystin/polyductin

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr 7:45,447,354...45,925,141
Ensembl chr 7:45,450,950...45,925,149

G

plasminogen activator, urokinase

severity

protein:increased expression:serum (human)

NCBI chr14:76,629,313...76,635,173
Ensembl chr14:76,629,299...76,635,172

G

phospholipase B1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:110,605,923...110,741,236
Ensembl chr 3:110,605,923...110,741,130

G

phospholipase C beta 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:17,915,984...18,402,540
Ensembl chr17:17,916,110...18,402,532

G

pleckstrin homology domain containing A4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:54,144,016...54,170,661
Ensembl chr 6:54,144,020...54,170,638

G

pleckstrin homology and RhoGEF domain containing G1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:15,341,634...15,588,224
Ensembl chr 1:15,341,638...15,587,590

G

pleckstrin homology and RhoGEF domain containing G4B

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:79,884,453...79,935,046

G

prostate transmembrane protein, androgen induced 1

disease_progression

NCBI chr17:57,999,287...58,054,329
Ensembl chr17:57,999,287...58,054,118

G

PMS1 homolog 2, mismatch repair system component

disease_progression

NCBI chr 3:5,118,002...5,145,634
Ensembl chr 3:5,118,018...5,145,628

G

pancreatic lipase related protein 1

NCBI chr14:126,796,943...126,812,152
Ensembl chr14:126,797,074...126,812,152

G

podocan

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:159,155,251...159,179,456
Ensembl chr 6:159,159,134...159,297,965

G

DNA polymerase kappa

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:25741868 PMID:26046662

NCBI chr 2:84,555,648...84,619,490
Ensembl chr 2:84,538,056...84,619,485

G

DNA polymerase nu

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:1,073,337...1,198,538
Ensembl chr 8:1,073,889...1,197,086

G

paraoxonase 1

protein:increased activity:serum (human)

NCBI chr 9:74,943,646...74,974,720
Ensembl chr 9:74,926,048...74,974,723

G

diphosphoinositol pentakisphosphate kinase 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:108,596,733...108,690,859
Ensembl chr 2:108,585,959...108,690,858

G

protein phosphatase 1 regulatory subunit 3C

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:103,273,401...103,278,757
Ensembl chr14:103,273,405...103,278,762

G

protein phosphatase 2 catalytic subunit alpha

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:136,497,780...136,522,630
Ensembl chr 2:136,494,541...136,522,646

G

protein phosphatase 2 regulatory subunit B'gamma

ClinVar Annotator: match by term: Malignant tumor of prostate

G

protein phosphatase 6 regulatory subunit 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:285,381...361,309
Ensembl chr 5:285,386...361,548

G

PPARG related coactivator 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:113,137,012...113,152,828
Ensembl chr14:113,137,037...113,152,831

G

phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1

protein:increased expression:prostate, lymph node

NCBI chr17:50,352,273...50,550,402
Ensembl chr17:50,354,775...50,550,637

G

phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:66,712,412...66,996,258
Ensembl chr 4:66,715,237...66,996,044

G

protein kinase D1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:69,527,743...69,872,374
Ensembl chr 7:69,527,811...69,872,863

G

peripherin 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:37,788,547...37,805,142
Ensembl chr 7:37,790,178...37,805,142

G

serine protease 22

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:39,365,798...39,376,909
Ensembl chr 3:39,365,803...39,380,476

G

proteasome 26S subunit, ATPase 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:112,027,904...112,041,360
Ensembl chr 7:112,027,921...112,041,489

G

phosphatase and tensin homolog

disease_progression

mRNA:decreased expression:tumor:lower in high versus low Gleason score tumors (p<0.05 compared to at least one housekeeping gene)
ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: Prostate cancer
DNA:deletion

RGD
OMIM
ClinVar

PMID:9259288 PMID:9399897 PMID:9467011 PMID:9856571 PMID:10232405 More...

RGD:2292502 RGD:2301729

NCBI chr14:99,929,590...100,021,619

G

prostaglandin-endoperoxide synthase 2

susceptibility

DNA:SNP:promoter:-1195G>A (human)

NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884

G

protein tyrosine kinase 2

protein:increased expression:prostate gland

NCBI chr 4:2,656,606...2,896,060
Ensembl chr 4:2,656,614...2,896,054

G

protein tyrosine kinase 2 beta

severity

protein:decreased expression:prostate gland

NCBI chr14:11,063,662...11,194,196
Ensembl chr14:11,064,492...11,194,192

G

protein tyrosine phosphatase non-receptor type 21

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:110,374,915...110,453,820
Ensembl chr 7:110,373,530...110,453,812

G

protein tyrosine phosphatase non-receptor type 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:250,418,131...250,583,148
Ensembl chr 1:250,418,133...250,540,480

G

protein tyrosine phosphatase receptor type D

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:211,832,409...214,013,013
Ensembl chr 1:213,483,348...214,009,893

G

protein tyrosine phosphatase receptor type N2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr18:721,125...1,389,609
Ensembl chr18:721,131...1,389,607

G

pyrroline-5-carboxylate reductase 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:959,709...964,195
Ensembl chr 4:959,710...964,192

G

RAB11 family interacting protein 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:43,360,758...43,474,235
Ensembl chr12:43,364,140...43,474,241

G

RAB33A, member RAS oncogene family

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:106,708,402...106,723,803
Ensembl chr X:106,712,398...106,723,404

G

Rac family small GTPase 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:10,553,986...10,571,082
Ensembl chr 5:10,553,433...10,573,014

G

RAD50 double strand break repair protein

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:26467025 PMID:28492532 PMID:33339169

NCBI chr 2:134,844,460...134,939,188
Ensembl chr 2:134,700,817...134,939,189

G

Raf-1 proto-oncogene, serine/threonine kinase

disease_progression

NCBI chr13:68,581,128...68,657,911
Ensembl chr13:68,580,812...68,657,829

G

Rap guanine nucleotide exchange factor like 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:22,180,928...22,195,841
Ensembl chr12:22,181,849...22,195,840

G

Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:106,900,826...106,997,795

G

RAS protein activator like 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:119,941,303...120,329,817
Ensembl chr 9:119,941,862...120,325,316

G

Ras association domain family member 1

disease_progression

DNA:hypermethylation:promoter

NCBI chr13:32,816,156...32,825,486
Ensembl chr13:32,816,156...32,825,226

G

RB transcriptional corepressor 1

DNA:loss of heterozygosity

NCBI chr11:19,186,754...19,317,642
Ensembl chr11:19,186,761...19,317,690

G

RB associated KRAB zinc finger

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:4,422,481...4,439,943
Ensembl chr 3:4,422,784...4,439,945

G

regulator of chromosome condensation 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:75,988,271...76,014,200
Ensembl chr 6:75,988,272...76,014,160

G

RERG like

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:54,939,384...54,952,059
Ensembl chr 5:54,939,887...54,955,629

G

Rho related BTB domain containing 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:7,223,209...7,254,813
Ensembl chr14:7,222,981...7,254,780

G

RIPOR family member 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:52,088,049...52,163,964
Ensembl chr17:52,088,053...52,162,554

G

ring finger protein, LIM domain interacting

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:59,889,799...59,920,464
Ensembl chr X:59,893,146...59,920,182

G

ribonuclease L

ClinVar Annotator: match by term: Prostate cancer

PMID:11799394 PMID:25741868 PMID:28492532

NCBI chr 9:123,895,045...123,910,386
Ensembl chr 9:123,893,294...123,910,398

G

ribosomal protein L10 like

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:176,603,177...176,604,116
Ensembl chr 1:176,603,248...176,603,892

G

ribosomal protein S6 kinase C1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:130,222,631...130,453,584
Ensembl chr 9:130,255,308...130,435,315

G

RNA pseudouridine synthase domain containing 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:41,009,722...41,013,013
Ensembl chr 3:41,009,717...41,013,018

G

regulator of telomere elongation helicase 1

susceptibility

DNA:SNP:cds:rs2297441|rs3208008 (human)

NCBI chr17:62,611,844...62,636,628
Ensembl chr17:62,611,909...62,634,690

G

rubicon like autophagy enhancer

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:20,995,439...21,036,429
Ensembl chr11:20,995,688...21,036,014

G

RUN domain containing 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:19,897,859...19,908,988
Ensembl chr12:19,897,862...19,908,912

G

S100 calcium binding protein A3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:96,084,049...96,086,829
Ensembl chr 4:96,084,088...96,086,827

G

scaffold attachment factor B2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:73,334,522...73,369,361
Ensembl chr 2:73,334,561...73,392,846

G

strawberry notch homolog 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:29,559,103...29,622,221
Ensembl chr14:29,571,125...29,620,090

G

sodium channel epithelial 1 subunit alpha

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:64,287,529...64,312,917
Ensembl chr 5:64,285,015...64,313,612

G

secernin 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr18:42,924,607...42,987,926
Ensembl chr18:42,924,409...42,987,923

G

signal peptide, CUB domain and EGF like domain containing 3

ClinVar Annotator: match by term: Prostate cancer

NCBI chr 7:31,113,596...31,153,095
Ensembl chr 7:31,114,082...31,150,000

G

sidekick cell adhesion molecule 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:2,814,418...3,327,838
Ensembl chr 3:2,814,547...3,324,798

G

serpin family B member 13

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:158,099,811...158,113,526
Ensembl chr 1:158,099,975...158,113,501

G

SET domain containing 5

severity

NCBI chr13:65,759,973...65,851,747
Ensembl chr13:65,759,987...65,850,506

G

SET domain bifurcated histone lysine methyltransferase 1

mRNA, protein:increased expression:prostate gland (human)

NCBI chr 4:98,259,801...98,293,238
Ensembl chr 4:98,260,375...98,293,097

G

seizure related 6 homolog like

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:43,802,482...44,001,643
Ensembl chr14:43,802,706...44,001,624

G

splicing factor 3b subunit 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:13,524,519...13,578,681
Ensembl chr 6:13,524,717...13,578,680

G

small G protein signaling modulator 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:48,416,774...48,462,851
Ensembl chr12:48,416,790...48,462,846

G

SHC binding and spindle associated 1 like

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:124,188,457...124,221,850
Ensembl chr 9:124,187,787...124,221,719

G

sucrase-isomaltase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:104,296,281...104,379,558
Ensembl chr13:104,296,283...104,379,478

G

sirtuin 1

disease_progression

NCBI chr14:71,091,167...71,126,351
Ensembl chr14:71,091,167...71,123,297

G

SKI3 subunit of superkiller complex

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:102,079,675...102,164,020
Ensembl chr 2:102,079,685...102,163,938

G

SKI like proto-oncogene

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:109,029,831...109,059,176
Ensembl chr13:109,029,952...109,059,173

G

S-phase kinase associated protein 2

disease_progression

NCBI chr16:21,463,270...21,500,925
Ensembl chr16:21,463,012...21,509,310

G

solute carrier family 13 member 3

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:25741868 PMID:28492532

NCBI chr17:48,714,180...48,792,280
Ensembl chr17:48,714,183...48,792,141

G

solute carrier family 16 member 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:59,748,685...59,861,018
Ensembl chr X:59,748,745...59,861,015

G

solute carrier family 25 member 22

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:491,288...498,773
Ensembl chr 2:491,293...498,767

G

solute carrier family 25 member 32

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:33,704,810...33,727,796
Ensembl chr 4:33,704,771...33,730,130

G

solute carrier family 25 member 47

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:121,204,213...121,210,376
Ensembl chr 7:121,192,433...121,210,374

G

SLC2A4 regulator

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:62,655,992...62,659,620
Ensembl chr17:62,657,566...62,659,615

G

solute carrier family 30 member 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:83,478,761...83,484,876
Ensembl chr 6:83,477,759...83,484,688

G

solute carrier family 34 member 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:80,548,208...80,563,380
Ensembl chr 2:80,548,232...80,563,321

G

solute carrier family 35 member C1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:16,650,771...16,658,891
Ensembl chr 2:16,647,193...16,658,672

G

solute carrier family 35 member G1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:105,335,063...105,345,277
Ensembl chr14:105,335,160...105,345,274

G

solute carrier family 46 member 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:5,983,198...6,000,728
Ensembl chr11:5,982,443...6,000,701

G

solute carrier family 5 member 2

ClinVar Annotator: match by term: Prostate cancer

PMID:23265383 PMID:25741868

NCBI chr 3:17,081,138...17,089,422
Ensembl chr 3:17,081,141...17,089,568

G

solute carrier family 5 member 7

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:47,994,116...48,020,744
Ensembl chr 3:47,996,335...48,022,379

G

solute carrier family 6 member 9

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr 6:167,267,193...167,301,598
Ensembl chr 6:167,268,963...167,301,599

G

solute carrier family 8 member A3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:93,643,609...93,797,483
Ensembl chr 7:93,643,618...93,796,917

G

solute carrier organic anion transporter family member 1B2

disease_progression

mRNA,protein:increased expression:prostate (human)

NCBI chr 5:52,137,454...52,206,236

G

SMAD family member 3

disease_progression

protein:increased expression:tumor:significantly elevated in 53/67 (79%, p=0.0002) overall, in 23/35 with Gleason score 6-7(66%) and 30/32 with Gleason score 8-10 (94%, p=0.0062); by immunohistochemistry

NCBI chr 1:164,998,457...165,124,455
Ensembl chr 1:164,998,103...165,124,449

G

SMAD family member 9

protein:altered localization

NCBI chr11:12,705,652...12,727,981
Ensembl chr11:12,705,368...12,763,008

G

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

disease_progression

NCBI chr 1:219,624,773...219,815,438
Ensembl chr 1:219,573,535...219,815,421

G

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

disease_progression
no_association

absence of somatic mutations in the samples used

PMID:12684665 PMID:17075831

RGD:2302527 RGD:2302528

NCBI chr 2:69,717,175...69,810,301
Ensembl chr 2:69,662,238...69,810,295

G

SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:21,563,426...21,586,790
Ensembl chr 5:21,563,400...21,586,737

G

single-strand-selective monofunctional uracil-DNA glycosylase 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:19,375,244...19,412,656
Ensembl chr 5:19,398,252...19,412,648

G

small nuclear ribonucleoprotein polypeptide E

severity

mRNA:increased expression:prostate gland (human)

NCBI chr 9:64,560,544...64,567,007
Ensembl chr 9:64,560,523...64,567,007

G

suppressor of cytokine signaling 1

DNA:hypermethylation

NCBI chr 3:31,879,143...31,883,041
Ensembl chr 3:31,881,225...31,884,967

G

sorbin and SH3 domain containing 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:106,895,764...107,137,469
Ensembl chr14:106,895,765...107,137,561

G

sortilin related VPS10 domain containing receptor 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:117,479,817...118,009,485
Ensembl chr14:117,479,787...118,009,583

G

SOS Ras/Rac guanine nucleotide exchange factor 1

NCBI chr 3:101,209,568...101,366,057
Ensembl chr 3:101,209,641...101,362,723

G

SRY-box transcription factor 9

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:8,642,154...8,647,315
Ensembl chr12:8,642,158...8,647,315

G

spermatogenesis associated 18

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:39,163,001...39,206,217
Ensembl chr 8:39,163,088...39,203,956

G

sperm antigen with calponin homology and coiled-coil domains 1 like

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:49,332,937...49,463,965
Ensembl chr14:49,333,009...49,463,963

G

serine peptidase inhibitor Kazal type 1

severity

protein:increased expression:prostate gland, serum

NCBI chr 2:149,072,652...149,079,529
Ensembl chr 2:149,071,703...149,079,499

G

speckle type BTB/POZ protein

ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: Prostate cancer

PMID:23265383 PMID:25741868

NCBI chr12:25,792,621...25,860,630
Ensembl chr12:25,792,630...25,860,595

G

SRC proto-oncogene, non-receptor tyrosine kinase

disease_progression

protein:increased tyrosine phosphorylation:prostate gland, membrane

NCBI chr17:40,470,970...40,524,862
Ensembl chr17:40,471,009...40,524,860

G

steroid 5 alpha-reductase 1

disease_progression

protein:increased expression:prostate gland
mRNA:increased expression:prostate gland (rat)

PMID:16818707 PMID:17720776

RGD:2302521 RGD:2302523

NCBI chr16:75,309,830...75,335,438
Ensembl chr16:75,310,211...75,335,391

G

steroid 5 alpha-reductase 2

susceptibility

mRNA:decreased expression:prostate gland
DNA:missense mutation:cds:p.A49T (human)

PMID:10501358 PMID:12949937

RGD:2302560 RGD:4891929

NCBI chr 3:107,840,200...107,918,351
Ensembl chr 3:107,840,200...107,918,350

G

sterol regulatory element binding transcription factor 2

disease_progression

NCBI chr 5:6,719,484...6,784,724
Ensembl chr 5:6,719,490...6,784,671

G

single stranded DNA binding protein 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:89,960,133...90,263,290
Ensembl chr 2:89,948,773...90,263,158

G

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:43,601,677...43,755,154
Ensembl chr10:43,602,908...43,755,277

G

signal transducer and activator of transcription 3

treatment

NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,992

G

signal transducer and activator of transcription 5A

disease_progression

DNA:CNV: :prostate (human)

NCBI chr12:20,474,221...20,498,785
Ensembl chr12:20,474,227...20,499,138

G

signal transducer and activator of transcription 6

disease_progression

mRNA, protein:increased expression:fibromuscular stroma, malignant epithelia:correlated with high histological grade and increased tumor size

NCBI chr 5:22,406,356...22,422,412
Ensembl chr 5:22,406,368...22,421,989

G

syntaxin 8

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:54,296,988...54,544,668
Ensembl chr12:54,296,995...54,544,646

G

syntaxin binding protein 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:268,116,124...268,205,805
Ensembl chr 1:268,116,120...268,205,778

G

SUFU negative regulator of hedgehog signaling

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr14:113,500,001...113,628,064
Ensembl chr14:113,500,842...113,626,003

G

sulfotransferase family 2A member 1

no_association
severity

DNA:missense mutations:cds:p.A63P (187G>C), p.A261T (781G>A) (human)
DNA:SNP:intron: (rs2547238) (human)

PMID:16617014 PMID:22542949

RGD:6893648 RGD:6893649

NCBI chr 6:53,525,496...53,536,723
Ensembl chr 6:53,524,787...53,536,718

G

synaptic vesicle glycoprotein 2B

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:87,564,380...87,767,247
Ensembl chr 7:87,568,026...87,766,335

G

synaptonemal complex protein 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:59,875,992...59,962,314
Ensembl chr17:59,875,993...59,955,209

G

synaptogyrin 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:8,870,641...8,902,267
Ensembl chr 5:8,870,645...8,902,270

G

TAO kinase 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:34,322,016...34,514,234
Ensembl chr14:34,409,070...34,513,025

G

transcription factor 3

severity

NCBI chr 2:76,859,079...76,906,275
Ensembl chr 2:76,859,089...76,898,351

G

transcription factor 7

severity

NCBI chr 2:136,422,740...136,456,323
Ensembl chr 2:136,422,940...136,457,910

G

transcription factor 7 like 2

disease_progression

DNA:SNP: :rs7903146 (human)
DNA:SNPs: :rs7094463, rs10749127, rs11196224 (human)

PMID:24961829 PMID:25678841

RGD:13506821 RGD:13506825

NCBI chr14:123,343,695...123,547,332
Ensembl chr14:123,343,412...123,546,417

G

telomerase reverse transcriptase

mRNA:increased expression:plasma

NCBI chr16:79,258,591...79,276,421
Ensembl chr16:79,258,591...79,276,421

G

testis expressed 14, intercellular bridge forming factor

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:34,815,472...34,975,901
Ensembl chr12:34,815,476...34,912,766

G

transferrin

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:74,930,655...74,970,599
Ensembl chr13:74,930,655...74,972,763

G

trefoil factor 1

disease_progression

protein:increased expression:plasma
mRNA:increased expression:prostate gland

PMID:10458410 PMID:16467092

RGD:2291999 RGD:2298571

NCBI chr13:205,687,558...205,691,512
Ensembl chr13:205,687,560...205,691,460

G

trefoil factor 2

disease_progression

protein:increased expression:plasma

NCBI chr13:205,669,014...205,672,319
Ensembl chr13:205,669,014...205,672,324

G

trefoil factor 3

disease_progression

protein:increased expression:plasma

NCBI chr13:205,641,038...205,644,333
Ensembl chr13:205,641,038...205,644,333

G

transferrin receptor

protein:increased expression:serum

NCBI chr13:133,976,765...133,997,554
Ensembl chr13:133,970,985...134,000,276

G

thyroglobulin

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:8,158,395...8,382,435
Ensembl chr 4:8,158,396...8,382,435

G

transforming growth factor beta 1

protein:increased expression:prostate gland

NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,173...49,349,046

G

transforming growth factor beta receptor 2

OMIM:176807 | OMIM:300147 | OMIM:300704 | OMIM:601518 | OMIM:602759 | OMIM:608656 | OMIM:608658 | OMIM:609299 | OMIM:609558 | OMIM:610321 | OMIM:610997 | OMIM:611100 | OMIM:611868 | OMIM:611928 | OMIM:611955 | OMIM:611958 | OMIM:611959

NCBI chr13:16,784,370...16,875,828
Ensembl chr13:16,784,490...16,878,160

G

transforming growth factor beta receptor 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:125,109,939...125,310,788
Ensembl chr 4:125,110,072...125,316,796

G

thrombospondin 1

mRNA:decreased expression:prostate gland

NCBI chr 1:131,728,781...131,746,098
Ensembl chr 1:131,728,784...131,746,115

G

thrombospondin 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:94,612,702...94,623,905
Ensembl chr 4:94,611,593...94,623,902

G

thyroid hormone receptor beta

DNA:loss of heterozygosity (human)

NCBI chr13:10,900,716...11,360,587
Ensembl chr13:10,900,724...11,359,544

G

TIMP metallopeptidase inhibitor 2

disease_progression

DNA, protein:hypermethylation, decreased expression:promoter, prostate gland
protein:increased expression:prostate gland

PMID:17325663 PMID:18329693

RGD:2290389 RGD:2290397

NCBI chr12:3,254,794...3,300,835
Ensembl chr12:3,254,493...3,300,834

G

TIMP metallopeptidase inhibitor 3

disease_progression

mRNA:decreased expression:prostate gland

NCBI chr 5:12,185,816...12,242,599
Ensembl chr 5:12,185,818...12,242,581

G

TLE family member 5, transcriptional modulator

associated with metastasis;protein:decreased expression:prostate

NCBI chr 2:75,492,208...75,501,543
Ensembl chr 2:75,492,233...75,501,542

G

toll like receptor 2

susceptibility

DNA:deletion:promoter:−196_−174del (human)

NCBI chr 8:75,416,257...75,428,370
Ensembl chr 8:75,411,993...75,428,330

G

transmembrane and coiled-coil domains 5A

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:133,291,660...133,383,696
Ensembl chr 1:133,285,037...133,302,309

G

transmembrane protein with EGF like and two follistatin like domains 2

disease_progression

DNA:hypermethylation

PMID:15299075 PMID:16458425 PMID:16500022

RGD:2290485 RGD:2290486 RGD:2290490

NCBI chr15:96,594,901...96,856,848
Ensembl chr15:96,594,970...96,855,743

G

transmembrane protein 183A

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:113,713,046...113,726,645
Ensembl chr 9:113,713,032...113,725,847

G

transmembrane protein 230

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:14,125,728...14,136,443
Ensembl chr17:14,125,730...14,136,387

G

transmembrane protein 94

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:5,870,092...5,905,789
Ensembl chr12:5,870,096...5,905,345

G

tumor necrosis factor

NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415

G

TNF receptor superfamily member 8

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:72,103,309...72,174,882

G

DNA topoisomerase II alpha

NCBI chr12:22,001,300...22,028,452
Ensembl chr12:22,001,282...22,028,450

G

TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:33,865,967...33,878,135
Ensembl chr10:33,865,959...33,879,070

G

tumor protein p53

disease_progression

DNA:mutations:exon
ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: Prostate cancer

PMID:1467311 PMID:1565144 PMID:2750177 PMID:7887414 PMID:7969167 More...

NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818

G

tumor protein p63

ClinVar Annotator: match by term: Prostate cancer

PMID:23265383 PMID:28492532

NCBI chr13:127,115,990...127,347,082
Ensembl chr13:127,116,105...127,347,068

G

tumor protein p73

mRNA:alternative forms

NCBI chr 6:65,169,770...65,228,997
Ensembl chr 6:65,182,456...65,228,990

G

tripartite motif containing 28

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:63,094,382...63,101,532
Ensembl chr 6:63,094,648...63,101,531

G

tripartite motif containing 34

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:4,175,660...4,188,528
Ensembl chr 9:4,174,294...4,183,440

G

tripartite motif family like 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:7,284,392...7,290,639
Ensembl chr17:7,283,709...7,292,681

G

thyroid hormone receptor interactor 12

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:130,784,567...130,940,497
Ensembl chr15:130,787,864...130,939,783

G

transient receptor potential cation channel subfamily C member 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:83,436,343...83,498,419
Ensembl chr13:83,436,395...83,498,478

G

transient receptor potential cation channel subfamily C member 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:13,300,288...13,519,001
Ensembl chr11:13,298,992...13,517,502

G

transient receptor potential cation channel subfamily M member 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:223,833,263...224,682,424
Ensembl chr 1:223,836,213...224,680,389

G

transformation/transcription domain associated protein

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:5,903,205...6,029,343
Ensembl chr 3:5,909,022...6,029,333

G

tumor susceptibility 101

mRNA:alternative forms:cds:multiple

NCBI chr 2:40,673,187...40,720,681

G

teashirt zinc finger homeobox 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:41,345,466...41,429,239
Ensembl chr 6:41,345,470...41,423,700

G

translin associated factor X interacting protein 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:28,428,531...28,453,743
Ensembl chr 6:28,428,917...28,450,563

G

tetraspanin 5

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:121,657,320...121,843,296
Ensembl chr 8:121,657,325...121,843,242

G

unc-51 like autophagy activating kinase 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:59,806,904...59,878,398
Ensembl chr12:59,806,955...59,878,388

G

uromodulin like 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:205,425,338...205,494,492
Ensembl chr13:205,425,454...205,491,629

G

unc-79 homolog, NALCN channel complex subunit

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:114,766,273...115,028,344
Ensembl chr 7:114,766,489...115,027,711

G

URB2 ribosome biogenesis homolog

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:60,229,026...60,254,462
Ensembl chr14:60,229,112...60,254,974

G

upstream transcription factor 2, c-fos interacting

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:44,774,417...44,783,594
Ensembl chr 6:44,774,008...44,783,592

G

usherin

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:5,825,591...6,662,733

G

ubiquitin specific peptidase 28

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:41,417,560...41,481,044
Ensembl chr 9:41,417,564...41,480,994

G

ubiquitin specific peptidase 48

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:79,744,928...79,810,241
Ensembl chr 6:79,744,932...79,810,220

G

UV radiation resistance associated

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:10,088,779...10,370,857
Ensembl chr 9:10,088,798...10,370,855

G

versican

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr 2:91,682,177...91,811,674
Ensembl chr 2:91,384,391...91,811,208

G

voltage dependent anion channel 1

DNA:SNP: :rs7250897 (human)

NCBI chr 2:136,302,188...136,334,461
Ensembl chr 2:136,302,191...136,396,301

G

vitamin D receptor

susceptibility

DNA:SNP: :rs11574143 (human)

NCBI chr 5:78,205,807...78,266,505
Ensembl chr 5:78,205,810...78,266,475

G

vascular endothelial growth factor A

NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,366

G

vitamin K epoxide reductase complex subunit 1 like 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:16,691,143...16,764,097
Ensembl chr 3:16,688,898...16,764,251

G

vanin 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:30,961,520...30,970,945

G

WD repeat and FYVE domain containing 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:133,665,585...133,939,860
Ensembl chr 8:133,675,345...133,937,221

G

WD repeat domain 49

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:106,348,216...106,492,792
Ensembl chr13:106,348,219...106,492,808

G

WAP four-disulfide core domain 1

disease_progression

protein:decreased expression, increased expression:connective tissue, epithelium
mRNA:decreased expression:prostate gland

PMID:15305341 PMID:15305342

RGD:2291859 RGD:2291860

NCBI chr 6:4,333,729...4,365,122
Ensembl chr 6:4,333,731...4,399,237

G

WNT inhibitory factor 1

mRNA, protein:decreased expression:prostate gland

NCBI chr 5:29,450,442...29,543,913
Ensembl chr 5:29,450,442...29,543,913

G

Wnt family member 2

mRNA:decreased expression:prostate gland

NCBI chr18:28,945,825...28,993,969
Ensembl chr18:28,946,326...28,993,961

G

WWC family member 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:6,815,648...6,930,939
Ensembl chr X:6,815,202...6,930,934

G

X-linked inhibitor of apoptosis

disease_progression

protein:increased expression:prostate gland

PMID:17947468 PMID:19415464

RGD:2315849 RGD:2315852

NCBI chr X:101,399,374...101,440,021
Ensembl chr X:101,399,812...101,440,013

G

X-ray repair cross complementing 1

susceptibility

DNA:polymorphism: :p.R399Q

NCBI chr 6:50,403,691...50,425,730
Ensembl chr 6:50,403,689...50,425,729

G

YTH N6-methyladenosine RNA binding protein C2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:118,003,402...118,092,176
Ensembl chr 2:117,897,260...118,092,175

G

zinc finger DHHC-type palmitoyltransferase 8

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:51,503,074...51,517,577
Ensembl chr14:51,503,114...51,516,885

G

zinc finger homeobox 3

susceptibility

NCBI chr 6:15,693,987...15,941,301
Ensembl chr 6:15,698,199...15,863,270

G

zinc finger with KRAB and SCAN domains 1

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:7,920,640...7,959,462
Ensembl chr 3:7,920,675...7,942,498

G

zinc finger matrin-type 3

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:117,113,272...117,147,639
Ensembl chr13:117,117,626...117,147,604

G

zinc finger protein 184

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:21,413,273...21,435,236
Ensembl chr 7:21,413,350...21,435,221

G

zinc finger protein 287

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:59,038,737...59,056,979
Ensembl chr12:59,038,774...59,053,204

G

zinc finger protein 304

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:61,740,677...61,790,290
Ensembl chr 6:61,740,708...61,748,689

G

zinc finger protein 48

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:17,920,884...17,925,593
Ensembl chr 3:17,921,033...17,925,590

G

zona pellucida glycoprotein 4

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:53,577,138...53,584,544
Ensembl chr14:53,577,135...53,584,546

G

zinc finger and SCAN domain containing 2

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:52,910,839...52,958,007
Ensembl chr 7:52,910,849...52,957,983

castration-resistant prostate carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aldo-keto reductase family 1, member C1

CTD Direct Evidence: marker/mechanism
mRNA,protein:increased expression:epithelial cell:

PMID:23196782 PMID:25555457

NCBI chr10:65,580,297...65,594,998
Ensembl chr10:65,576,464...65,678,248

G

androgen receptor

CTD Direct Evidence: marker/mechanism

PMID:18985049 PMID:24740322 PMID:28500234 PMID:28757136

NCBI chr X:53,609,113...53,806,778
Ensembl chr X:53,609,176...53,800,677

G

anti-silencing function 1B histone chaperone

CTD Direct Evidence: marker/mechanism

NCBI chr 2:65,063,186...65,072,681
Ensembl chr 2:65,062,766...65,072,679

G

cyclin E2

treatment

NCBI chr 4:41,802,090...41,821,870
Ensembl chr 4:41,804,377...41,821,874

G

CD46 molecule, complement regulatory protein

CTD Direct Evidence: marker/mechanism

NCBI chr 9:135,025,439...135,078,910

G

centromere protein K

CTD Direct Evidence: marker/mechanism

NCBI chr16:44,008,673...44,080,565
Ensembl chr16:44,041,490...44,080,492

G

chromodomain helicase DNA binding protein 1

DNA:mutations: :

NCBI chr 2:105,113,149...105,205,303
Ensembl chr 2:105,113,668...105,203,119

G

lysine demethylase 1A

CTD Direct Evidence: marker/mechanism

NCBI chr 6:80,903,407...80,971,875
Ensembl chr 6:80,903,424...80,971,873

G

NUF2 component of NDC80 kinetochore complex

treatment

NCBI chr 4:87,162,873...87,194,193
Ensembl chr 4:87,162,818...87,194,170

G

signal transducer and activator of transcription 5A

treatment
disease_progression

DNA:CNV: :prostate (human)

NCBI chr12:20,474,221...20,498,785
Ensembl chr12:20,474,227...20,499,138

G

tripartite motif containing 24

CTD Direct Evidence: marker/mechanism

NCBI chr18:11,055,211...11,151,755
Ensembl chr18:11,055,213...11,151,404

G

zinc finger protein 217

CTD Direct Evidence: marker/mechanism

NCBI chr17:54,605,939...54,648,868
Ensembl chr17:54,605,943...54,648,736

G

zinc finger protein 367

CTD Direct Evidence: marker/mechanism

NCBI chr10:25,707,711...25,735,073
Ensembl chr10:25,707,722...25,735,067

Familial Prostate Cancer

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adhesion G protein-coupled receptor G1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:19,523,618...19,570,891
Ensembl chr 6:19,527,648...19,570,893

G

androgen receptor

ClinVar Annotator: match by term: Prostate cancer susceptibility

PMID:8530589 PMID:10589774 PMID:11103816 PMID:28492532

NCBI chr X:53,609,113...53,806,778
Ensembl chr X:53,609,176...53,800,677

G

Rho GTPase activating protein 6

CTD Direct Evidence: marker/mechanism

NCBI chr X:7,910,851...8,441,579
Ensembl chr X:7,910,858...8,120,386

G

alpha tubulin acetyltransferase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 7:23,173,138...23,185,463
Ensembl chr 7:23,173,438...23,185,451

G

ATM serine/threonine kinase

ClinVar Annotator: match by term: Familial prostate cancer

PMID:15928302 PMID:16199547 PMID:16941484 PMID:17124347 PMID:17910737 More...

NCBI chr 9:36,620,656...36,759,555
Ensembl chr 9:36,620,657...36,759,552

G

beta-1,3-glucuronyltransferase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 9:60,995,280...61,020,300
Ensembl chr 9:60,995,277...61,020,103

G

brain enriched myelin associated protein 1

CTD Direct Evidence: marker/mechanism

NCBI chr17:54,920,714...55,039,470
Ensembl chr17:54,920,712...55,039,346

G

BCL2 apoptosis regulator

CTD Direct Evidence: marker/mechanism

NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879

G

BCL2 like 11

CTD Direct Evidence: marker/mechanism

NCBI chr 3:45,156,791...45,202,996
Ensembl chr 3:45,160,155...45,201,186

G

bridge-like lipid transfer protein family member 3A

CTD Direct Evidence: marker/mechanism

NCBI chr 7:30,731,466...30,799,958
Ensembl chr 7:30,731,461...30,802,735

G

BRCA1 DNA repair associated

ClinVar Annotator: match by term: Familial prostate cancer

PMID:17319787 PMID:18489799 PMID:20104584 PMID:21203900 PMID:25525159 More...

NCBI chr12:19,788,087...19,854,515
Ensembl chr12:19,786,020...19,854,668

G

BRCA2 DNA repair associated

ClinVar Annotator: match by term: Familial prostate cancer | ClinVar Annotator: match by term: Hereditary Prostate Cancer | ClinVar Annotator: match by term: Hereditary prostate cancer

PMID:186727 PMID:251866 PMID:8075631 PMID:8524414 PMID:8589730 More...

NCBI chr11:8,805,950...8,858,128
Ensembl chr11:8,805,913...8,857,793

G

chromosome 9 C11orf65 homolog

ClinVar Annotator: match by term: Familial prostate cancer

PMID:15928302 PMID:16941484 PMID:17124347 PMID:17910737 PMID:19431188 More...

NCBI chr 9:36,768,819...36,855,318
Ensembl chr 9:36,776,897...36,849,710

G

caspase 8

CTD Direct Evidence: marker/mechanism

NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468

G

cell division cycle associated 7

CTD Direct Evidence: marker/mechanism

NCBI chr15:79,406,837...79,447,571
Ensembl chr15:79,432,667...79,447,568

G

cadherin 1

ClinVar Annotator: match by term: Hereditary prostate cancer | ClinVar Annotator: match by term: Prostate cancer susceptibility

PMID:11948460 PMID:14961571 PMID:15235021 PMID:16061854 PMID:16189707 More...

NCBI chr 6:18,075,487...18,155,986
Ensembl chr 6:18,075,480...18,155,986

G

cyclin dependent kinase inhibitor 1B

CTD Direct Evidence: marker/mechanism

NCBI chr 5:59,731,224...59,735,831
Ensembl chr 5:59,731,206...59,735,831

G

chromodomain helicase DNA binding protein 3

CTD Direct Evidence: marker/mechanism

NCBI chr12:53,135,767...53,163,244
Ensembl chr12:53,139,366...53,163,243

G

checkpoint kinase 2

ClinVar Annotator: match by term: Familial prostate cancer | ClinVar Annotator: match by term: Hereditary Prostate Cancer | ClinVar Annotator: match by term: Hereditary prostate cancer | ClinVar Annotator: match by term: Prostate cancer susceptibility

PMID:9536098 PMID:10617473 PMID:11053450 PMID:11298456 PMID:11390408 More...

NCBI chr14:45,699,833...45,967,350
Ensembl chr14:45,929,715...45,967,290

G

collagen type XXIII alpha 1 chain

CTD Direct Evidence: marker/mechanism

NCBI chr 2:79,766,260...80,141,296
Ensembl chr 2:79,766,150...80,141,293

G

DENN domain containing 4B

CTD Direct Evidence: marker/mechanism

NCBI chr 4:95,745,878...95,762,192
Ensembl chr 4:95,748,140...95,761,519

G

DNA methyltransferase 3 beta

CTD Direct Evidence: marker/mechanism

NCBI chr17:36,345,715...36,386,076
Ensembl chr17:36,345,816...36,386,072

G

dedicator of cytokinesis 2

CTD Direct Evidence: marker/mechanism

NCBI chr16:53,843,248...54,248,708
Ensembl chr16:53,843,252...54,248,638

G

EMSY transcriptional repressor, BRCA2 interacting

CTD Direct Evidence: marker/mechanism

NCBI chr 9:10,628,053...10,715,814
Ensembl chr 9:10,628,053...10,716,396

G

fibrosin like 1

CTD Direct Evidence: marker/mechanism

NCBI chr14:22,890,052...22,977,364
Ensembl chr14:22,887,227...22,977,450

G

HAUS augmin like complex subunit 6

CTD Direct Evidence: marker/mechanism

NCBI chr 1:203,720,253...203,771,222
Ensembl chr 1:203,720,264...203,771,138

G

homeobox B13

ClinVar Annotator: match by term: Prostate cancer susceptibility

PMID:8756292 PMID:15964834 PMID:17138648 PMID:22236224 PMID:22714738 More...

NCBI chr12:24,948,307...24,950,661
Ensembl chr12:24,947,687...24,950,714

G

inner centromere protein

CTD Direct Evidence: marker/mechanism

NCBI chr 2:9,411,942...9,445,825
Ensembl chr 2:9,411,942...9,445,821

G

integrin subunit beta 8

CTD Direct Evidence: marker/mechanism

NCBI chr 9:89,342,245...89,450,701
Ensembl chr 9:89,341,162...89,448,665

G

lysine demethylase 2A

CTD Direct Evidence: marker/mechanism

NCBI chr 2:5,238,690...5,357,799
Ensembl chr 2:5,240,312...5,357,829

G

kinetochore scaffold 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:130,652,493...130,728,989

G

La ribonucleoprotein 4B

CTD Direct Evidence: marker/mechanism

NCBI chr10:68,621,596...68,707,894

G

mitotic arrest deficient 1 like 1

CTD Direct Evidence: marker/mechanism

NCBI chr 3:1,236,066...1,559,346
Ensembl chr 3:1,236,076...1,559,041

G

mitogen-activated protein kinase kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:164,381,892...164,469,313
Ensembl chr 1:164,381,845...164,471,226

G

methyl-CpG binding domain protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:103,683,077...103,768,372
Ensembl chr 1:103,735,192...103,752,402

G

muscleblind like splicing regulator 1

CTD Direct Evidence: marker/mechanism

NCBI chr13:92,491,778...92,696,235
Ensembl chr13:92,491,808...92,696,230

G

MDS1 and EVI1 complex locus

CTD Direct Evidence: marker/mechanism

NCBI chr13:107,753,207...108,336,136
Ensembl chr13:107,754,482...108,335,702

G

matrix metallopeptidase 14

CTD Direct Evidence: marker/mechanism

NCBI chr 7:76,174,502...76,185,931
Ensembl chr 7:76,172,971...76,185,928

G

MOB kinase activator 2

CTD Direct Evidence: marker/mechanism

NCBI chr 2:959,203...993,674
Ensembl chr 2:958,904...971,402

G

mutS homolog 6

ClinVar Annotator: match by term: Hereditary prostate cancer

PMID:18269114 PMID:24362816 PMID:25741868 PMID:28492532

NCBI chr 3:92,792,590...92,814,154
Ensembl chr 3:92,785,664...92,814,238

G

myosin IXB

CTD Direct Evidence: marker/mechanism

NCBI chr 2:60,455,605...60,567,479
Ensembl chr 2:60,455,607...60,567,467

G

paired box 9

CTD Direct Evidence: marker/mechanism

NCBI chr 7:63,324,709...63,346,326
Ensembl chr 7:63,324,711...63,346,310

G

PBX/knotted 1 homeobox 2

CTD Direct Evidence: marker/mechanism

NCBI chr 9:52,303,022...52,608,505
Ensembl chr 9:52,349,714...52,610,680

G

POU class 2 homeobox 2

CTD Direct Evidence: marker/mechanism

NCBI chr 6:49,791,937...49,829,771
Ensembl chr 6:49,727,012...49,825,816

G

PPFIA binding protein 2

CTD Direct Evidence: marker/mechanism

NCBI chr 9:1,984,717...2,141,428
Ensembl chr 9:1,987,841...2,141,398

G

phosphatase and tensin homolog

ClinVar Annotator: match by term: Hereditary Prostate Cancer

PMID:12844284 PMID:12938083 PMID:17847000 PMID:21194675 PMID:21956414 More...

NCBI chr14:99,929,590...100,021,619

G

Ras association domain family member 3

CTD Direct Evidence: marker/mechanism

NCBI chr 5:28,949,787...29,113,894
Ensembl chr 5:29,025,549...29,113,890

G

regulatory factor X7

CTD Direct Evidence: marker/mechanism

NCBI chr 1:115,732,167...115,871,951
Ensembl chr 1:115,734,347...115,871,084

G

ribonuclease L

ClinVar Annotator: match by term: Prostate cancer susceptibility

PMID:12415269 PMID:16609730 PMID:25741868

NCBI chr 9:123,895,045...123,910,386
Ensembl chr 9:123,893,294...123,910,398

G

ring finger protein 43

CTD Direct Evidence: marker/mechanism

NCBI chr12:34,631,574...34,695,021
Ensembl chr12:34,635,228...34,694,378

G

renalase, FAD dependent amine oxidase

CTD Direct Evidence: marker/mechanism

NCBI chr14:100,312,592...100,604,953
Ensembl chr14:100,317,625...100,605,063

G

major histocompatibility complex, class II, DO alpha

CTD Direct Evidence: marker/mechanism

NCBI chr 7:25,178,866...25,182,665
Ensembl chr 7:25,178,881...25,182,707

G

succinyl-CoA:glutarate-CoA transferase

CTD Direct Evidence: marker/mechanism

NCBI chr18:53,639,588...54,283,272
Ensembl chr18:53,639,872...54,283,251

G

transcription factor 4

CTD Direct Evidence: marker/mechanism

NCBI chr 1:104,718,809...105,079,919
Ensembl chr 1:104,719,151...105,079,919

G

transcription factor 7 like 2

CTD Direct Evidence: marker/mechanism

NCBI chr14:123,343,695...123,547,332
Ensembl chr14:123,343,412...123,546,417

G

torsin family 1 member A

CTD Direct Evidence: marker/mechanism

NCBI chr 1:269,975,919...269,985,478
Ensembl chr 1:269,974,935...269,985,523

G

teashirt zinc finger homeobox 1

CTD Direct Evidence: marker/mechanism

NCBI chr 1:148,905,179...148,984,984
Ensembl chr 1:148,906,075...148,984,832

G

tetratricopeptide repeat domain 28

CTD Direct Evidence: marker/mechanism

NCBI chr14:45,317,793...45,925,026
Ensembl chr14:45,320,600...45,925,098

prostate adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adiponectin, C1Q and collagen domain containing

susceptibility

DNA:SNPs, haplotypes:5' utr, introns, exon:multiple

NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,685...124,646,646

G

adiponectin receptor 1

susceptibility

DNA:SNPs, haplotype:intron, exon: (rs12733285, rs7539452) (human)

NCBI chr10:24,907,491...24,923,540
Ensembl chr10:24,907,491...24,915,686

G

AKT serine/threonine kinase 1

treatment

G

AKT serine/threonine kinase 2

treatment

NCBI chr 6:48,555,785...48,620,472
Ensembl chr 6:48,555,795...48,587,919

G

AKT serine/threonine kinase 3

treatment

NCBI chr10:16,441,465...16,741,745
Ensembl chr10:16,441,447...16,741,337

G

androgen receptor

treatment

NCBI chr X:53,609,113...53,806,778
Ensembl chr X:53,609,176...53,800,677

G

bridging integrator 1

NCBI chr15:25,328,679...25,379,675
Ensembl chr15:25,328,674...25,383,652

G

baculoviral IAP repeat containing 6

ameliorates

mRNA:increased expression:prostate gland (human)

NCBI chr 3:107,012,967...107,269,370
Ensembl chr 3:107,012,986...107,269,477

G

baculoviral IAP repeat containing 7

exacerbates

mRNALincreased expression:prostate gland (human)

NCBI chr17:62,351,663...62,356,220

G

B-Raf proto-oncogene, serine/threonine kinase

NCBI chr18:8,957,963...9,132,558
Ensembl chr18:8,957,991...9,132,553

G

calcium/calmodulin dependent protein kinase II inhibitor 1

treatment

NCBI chr 6:78,730,204...78,734,232
Ensembl chr 6:78,730,206...78,733,740

G

cyclin B1

severity

NCBI chr16:47,338,239...47,348,385
Ensembl chr16:47,338,110...47,348,377

G

cyclin E2

NCBI chr 4:41,802,090...41,821,870
Ensembl chr 4:41,804,377...41,821,874

G

CD9 molecule

disease_progression

DNA, mRNA:deletion, point mutation, decreased expression:prostate gland

NCBI chr 5:64,420,177...64,459,783
Ensembl chr 5:64,420,182...64,460,304

G

chromodomain helicase DNA binding protein 4

mRNA:decreased expression:prostate gland (human)

NCBI chr 5:64,071,627...64,105,212
Ensembl chr 5:64,065,992...64,105,173

G

component of inhibitor of nuclear factor kappa B kinase complex

treatment

NCBI chr14:111,316,178...111,351,669
Ensembl chr14:111,315,141...111,351,868

G

clusterin

treatment

NCBI chr14:11,336,585...11,352,569
Ensembl chr14:11,336,595...11,349,764

G

cAMP responsive element binding protein 3 like 4

PMID:11830526 PMID:17270658

RGD:13504714 RGD:13504715

NCBI chr 4:95,716,530...95,723,959
Ensembl chr 4:95,716,537...95,722,947

G

catenin beta 1

ClinVar Annotator: match by term: Prostate adenocarcinoma

PMID:10192393 PMID:25741868 PMID:26619011

NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,164,277...25,208,311

G

DNA methyltransferase 1

mRNA,protein:increased expression:prostate gland:

NCBI chr 2:68,981,564...69,040,364
Ensembl chr 2:68,981,566...69,029,844

G

DNA methyltransferase 3 alpha

mRNA:increased expression:prostate gland:

NCBI chr 3:113,501,972...113,609,148
Ensembl chr 3:113,528,926...113,603,087

G

DNA methyltransferase 3 beta

mRNA,protein:increased expression:prostate gland:

NCBI chr17:36,345,715...36,386,076
Ensembl chr17:36,345,816...36,386,072

G

fibroblast growth factor 2

disease_progression

NCBI chr 8:101,278,877...101,344,084
Ensembl chr 8:101,278,885...101,343,916

G

fibroblast growth factor receptor 1

PMID:18068632 PMID:23576558

RGD:13504748 RGD:2298702

NCBI chr15:48,053,895...48,106,634
Ensembl chr15:48,053,340...48,106,724

G

growth factor receptor bound protein 2

NCBI chr12:5,940,723...6,009,095
Ensembl chr12:5,940,647...6,010,835

G

HRas proto-oncogene, GTPase

ClinVar Annotator: match by term: Adenocarcinoma of prostate | ClinVar Annotator: match by term: Prostate adenocarcinoma

PMID:1904555 PMID:3510078 PMID:11150980 PMID:16155195 PMID:16170316 More...

NCBI chr 2:299,662...302,539
Ensembl chr 2:299,660...302,501

G

isocitrate dehydrogenase (NADP(+)) 1

ClinVar Annotator: match by term: Prostate adenocarcinoma

PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20946881 More...

NCBI chr15:111,341,153...111,362,330
Ensembl chr15:111,341,153...111,362,296

G

insulin like growth factor 1 receptor

treatment
disease_progression

PMID:8692980 PMID:25442907 PMID:25862373 PMID:26452103

RGD:13504753 RGD:13504767 RGD:13504768 RGD:13504771

NCBI chr 1:137,383,623...137,691,038
Ensembl chr 1:137,387,825...137,691,058

G

inhibitor of nuclear factor kappa B kinase subunit beta

treatment

NCBI chr17:11,289,607...11,348,557
Ensembl chr17:11,289,690...11,348,549

G

integrin linked kinase

disease_progression

protein:increased expression:tumor: high-grade tumors versus adjacent BHP (P<0.001), BHP from cancer-free patients (P<0.002), or low-grade tumors (P=0.003), also associated with proliferative index (P=0.001), but inversely related to 5-year survival (p=0.004)

NCBI chr 9:3,145,647...3,152,097
Ensembl chr 9:3,145,608...3,159,858

G

insulin receptor

treatment

NCBI chr 2:71,797,209...71,939,923
Ensembl chr 2:71,797,204...71,936,104

G

Jun proto-oncogene, AP-1 transcription factor subunit

disease_progression

protein:increased expression, increased activation:significantly higher levels in invading vs organ-confined specimens (P<0.001)

NCBI chr 6:153,686,425...153,687,635
Ensembl chr 6:153,685,682...153,687,636

G

kinase insert domain receptor

protein:increased expression:tumor:relative to benign prostatic hypertrophy (BPH) tissue
protein:increased expression:prostate gland

PMID:17491265 PMID:20808233

RGD:2291925 RGD:5684541

NCBI chr 8:41,809,116...41,856,379
Ensembl chr 8:41,809,122...41,856,336

G

mitogen-activated protein kinase kinase 1

disease_progression

metastasis; inhibition reduced invasiveness of prostate tumor cells

NCBI chr 1:164,381,892...164,469,313
Ensembl chr 1:164,381,845...164,471,226

G

mitogen-activated protein kinase 1

treatment

PMID:22139534 PMID:28492138

RGD:13504818 RGD:13504820

NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513

G

MYC proto-oncogene, bHLH transcription factor

human gene in mouse model

PMID:14522256 PMID:20195545

RGD:7207413 RGD:7207781

NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,122...12,461,078

G

nuclear receptor coactivator 2

ameliorates

human cells in mouse model

NCBI chr 4:64,888,029...65,245,757
Ensembl chr 4:64,954,238...65,246,572

G

NFKB inhibitor alpha

severity

protein:increased serine phosphorylation

PMID:15073126 PMID:15712212

RGD:13506768 RGD:2298768

NCBI chr 7:64,508,119...64,510,754
Ensembl chr 7:64,507,822...64,511,277

G

peptidylglycine alpha-amidating monooxygenase

mRNA:increased expression:prostate gland (human)

NCBI chr 2:108,255,923...108,536,192
Ensembl chr 2:108,255,930...108,536,880

G

platelet derived growth factor subunit A

protein:increased expression:prostate

NCBI chr 3:296,399...322,967
Ensembl chr 3:301,584...321,712

G

platelet derived growth factor receptor alpha

protein:increased expression:prostate

NCBI chr 8:40,966,568...41,021,440
Ensembl chr 8:40,967,493...41,021,441

G

3-phosphoinositide dependent protein kinase 1

treatment

NCBI chr 3:39,429,928...39,512,623
Ensembl chr 3:39,432,058...39,512,601

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

ClinVar Annotator: match by term: Adenocarcinoma of prostate

PMID:15016963 PMID:15254419 PMID:15647370 PMID:15805248 PMID:18676830 More...

NCBI chr13:117,193,935...117,282,151
Ensembl chr13:117,180,544...117,274,587

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

treatment

NCBI chr13:79,427,033...79,610,840
Ensembl chr13:79,425,835...79,610,840

G

protein kinase C theta

mRNA:increased expression:prostate

NCBI chr10:64,442,588...64,596,528
Ensembl chr10:64,458,180...64,600,339

G

Raf-1 proto-oncogene, serine/threonine kinase

treatment

NCBI chr13:68,581,128...68,657,911
Ensembl chr13:68,580,812...68,657,829

G

RELA proto-oncogene, NF-kB subunit

disease_progression

protein:increased expression:prostate gland

PMID:15073126 PMID:15712212

RGD:13506768 RGD:2298768

NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469

G

signal transducer and activator of transcription 1

disease_progression

protein:increased activity:prostate

NCBI chr15:95,593,201...95,646,324
Ensembl chr15:95,593,211...95,646,260

G

telomerase reverse transcriptase

treatment

NCBI chr16:79,258,591...79,276,421
Ensembl chr16:79,258,591...79,276,421

G

tumor protein p53

ClinVar Annotator: match by term: Adenocarcinoma of prostate
ClinVar Annotator: match by term: Prostate adenocarcinoma

PMID:1565143 PMID:1565144 PMID:11370630 PMID:12826609 PMID:19468865 More...

NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818

Prostate Cancer, Hereditary, 1

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

B-Raf proto-oncogene, serine/threonine kinase

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

PMID:12068308 PMID:15035987 PMID:16439621 PMID:17096326 PMID:17119447 More...

NCBI chr18:8,957,963...9,132,558
Ensembl chr18:8,957,991...9,132,553

G

homeobox B13

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

PMID:9536098 PMID:17576681 PMID:25741868 PMID:26467025 PMID:28492532

NCBI chr12:24,948,307...24,950,661
Ensembl chr12:24,947,687...24,950,714

G

HRas proto-oncogene, GTPase

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

NCBI chr 2:299,662...302,539
Ensembl chr 2:299,660...302,501

G

KRAS proto-oncogene, GTPase

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

PMID:17056636 PMID:17468812 PMID:17704260 PMID:18386799 PMID:20949621 More...

NCBI chr 5:48,508,774...48,546,260
Ensembl chr 5:48,508,811...48,549,358

G

leucine rich repeat containing 56

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

NCBI chr 2:303,836...323,701
Ensembl chr 2:304,430...323,699

G

NRAS proto-oncogene, GTPase

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

NCBI chr 4:105,845,913...105,853,769
Ensembl chr 4:105,845,872...105,858,227

G

phosphatase and tensin homolog

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

PMID:9467011 PMID:9600246 PMID:10051160 PMID:12786840 PMID:16773562 More...

NCBI chr14:99,929,590...100,021,619

G

ribonuclease L

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1 | ClinVar Annotator: match by term: RNASEL-related condition

PMID:11799394 PMID:12415269 PMID:16609730 PMID:25741868 PMID:28492532

NCBI chr 9:123,895,045...123,910,386
Ensembl chr 9:123,893,294...123,910,398

G

tumor protein p53

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

PMID:12826609 PMID:20522432 PMID:25741868 PMID:27545002 PMID:28492532 More...

NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818

G

vascular endothelial growth factor A

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,366

Prostate Cancer, Hereditary, 12

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

EH domain binding protein 1

ClinVar Annotator: match by term: EHBP1-related condition | ClinVar Annotator: match by term: Prostate cancer, hereditary, 12

PMID:18264098 PMID:25741868

NCBI chr 3:78,907,315...79,261,890
Ensembl chr 3:78,907,317...79,257,760

Prostate Cancer, Hereditary, 13

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

microseminoprotein beta

ClinVar Annotator: match by term: Prostate cancer, hereditary, 13

PMID:18264096 PMID:18264097 PMID:19153072 PMID:19383797 PMID:19644707

NCBI chr14:90,533,092...90,542,309
Ensembl chr14:90,533,103...90,582,765

Prostate Cancer, Hereditary, 2

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

elaC ribonuclease Z 2

susceptibility

ClinVar Annotator: match by term: ELAC2-related condition | ClinVar Annotator: match by term: Prostate cancer, hereditary, 2

PMID:10986046 PMID:11175785 PMID:11254448 PMID:11507049 PMID:12515253 More...

NCBI chr12:57,206,596...57,238,438
Ensembl chr12:57,206,600...57,238,444

Prostate Cancer, Hereditary, 9

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

homeobox B13

ClinVar Annotator: match by term: HOXB13-related condition | ClinVar Annotator: match by term: Prostate cancer, hereditary, 9

PMID:8756292 PMID:15964834 PMID:17138648 PMID:22236224 PMID:22714738 More...

NCBI chr12:24,948,307...24,950,661
Ensembl chr12:24,947,687...24,950,714

Prostate Cancer, Hereditary, X-Linked 3

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

androgen receptor

ClinVar Annotator: match by term: Prostate cancer, hereditary, X-linked 3

PMID:17970778 PMID:23637914 PMID:25741868 PMID:27899157 PMID:28492532 More...

NCBI chr X:53,609,113...53,806,778
Ensembl chr X:53,609,176...53,800,677

Prostate Cancer, Somatic

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

androgen receptor

ClinVar Annotator: match by term: Prostate cancer, somatic

PMID:1631125 PMID:1779964 PMID:6541981 PMID:7723794 PMID:7795646 More...

NCBI chr X:53,609,113...53,806,778
Ensembl chr X:53,609,176...53,800,677

G

checkpoint kinase 2

ClinVar Annotator: match by term: Prostate cancer, somatic

PMID:12533788 PMID:16835864 PMID:16941491 PMID:18058223 PMID:18996005 More...

NCBI chr14:45,699,833...45,967,350
Ensembl chr14:45,929,715...45,967,290

G

KLF transcription factor 6

ClinVar Annotator: match by term: Prostate cancer, somatic

NCBI chr10:66,488,445...66,497,830
Ensembl chr10:66,488,391...66,497,844

G

mitotic arrest deficient 1 like 1

ClinVar Annotator: match by term: Prostate cancer, somatic

PMID:11423979 PMID:25741868

NCBI chr 3:1,236,066...1,559,346
Ensembl chr 3:1,236,076...1,559,041

G

phosphatase and tensin homolog

ClinVar Annotator: match by term: Prostate cancer, somatic

NCBI chr14:99,929,590...100,021,619

G

zinc finger homeobox 3

ClinVar Annotator: match by term: Prostate cancer, somatic

NCBI chr 6:15,693,987...15,941,301
Ensembl chr 6:15,698,199...15,863,270

Prostate Cancer/Brain Cancer Susceptibility

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

EPH receptor B2

ClinVar Annotator: match by term: Prostate cancer/brain cancer susceptibility

PMID:15300251 PMID:16155194 PMID:25741868 PMID:28492532

NCBI chr 6:80,649,098...80,849,979
Ensembl chr 6:80,650,740...80,843,567

prostate carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

AKT serine/threonine kinase 2

treatment

NCBI chr 6:48,555,785...48,620,472
Ensembl chr 6:48,555,795...48,587,919

G

angiopoietin 1

protein:increased expression:prostate gland

NCBI chr 4:29,925,203...30,233,434
Ensembl chr 4:29,933,135...30,233,960

G

activating transcription factor 4

treatment

NCBI chr 5:8,742,964...8,745,752
Ensembl chr 5:8,742,967...8,745,368

G

alpha-2-glycoprotein 1, zinc-binding

exacerbates

NCBI chr 3:7,867,521...7,874,857

G

BCL2 associated agonist of cell death

protein:increased expression:prostate gland

NCBI chr 2:7,831,192...7,842,864
Ensembl chr 2:7,830,920...7,842,863

G

BCL2 associated X, apoptosis regulator

disease_progression

protein:increased expression:prostate gland epithelium

NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,147

G

BCL2 like 1

NCBI chr17:35,366,139...35,415,798
Ensembl chr17:35,366,143...35,414,694

G

BCL2 like 14

mRNA:decreased expression:prostate gland

NCBI chr 5:60,334,813...60,357,935
Ensembl chr 5:60,332,451...60,357,897

G

bone morphogenetic protein 2

disease_progression

protein:increased expression:prostate gland

NCBI chr17:15,750,487...15,762,982
Ensembl chr17:15,749,835...15,761,195

G

bone morphogenetic protein 4

disease_progression

protein:increased expression:prostate

NCBI chr 1:183,415,989...183,422,888
Ensembl chr 1:183,416,146...183,422,637

G

caspase 6

mRNA:increased expression:prostate gland

NCBI chr 8:112,519,450...112,534,315
Ensembl chr 8:112,520,629...112,537,045

G

cyclin dependent kinase 13

ameliorates

NCBI chr18:54,310,311...54,430,060
Ensembl chr18:54,312,479...54,430,786

G

glycoprotein hormones, alpha polypeptide

mRNA:increased expression:prostate gland

NCBI chr 1:55,552,675...55,569,057
Ensembl chr 1:55,551,320...55,568,991

G

chitinase 3 like 1

severity

protein:increased secretion:serum (human)

NCBI chr 9:113,885,541...113,895,033
Ensembl chr 9:113,885,542...113,895,131

G

CRK like proto-oncogene, adaptor protein

protein:decreased tyrosine phosphorylation:prostate gland

NCBI chr14:50,528,950...50,558,664
Ensembl chr14:50,528,955...50,558,662

G

E2F transcription factor 5

ameliorates

NCBI chr 4:51,478,399...51,512,617
Ensembl chr 4:51,478,050...51,512,718

G

eukaryotic translation initiation factor 3 subunit H

DNA:amplification

NCBI chr 4:21,955,026...22,053,683
Ensembl chr 4:21,954,874...22,058,699

G

growth hormone releasing hormone

mRNA:increased expression:prostate

NCBI chr17:40,386,725...40,398,312
Ensembl chr17:40,387,344...40,397,857

G

histone deacetylase 2

disease_progression

protein:increased expression:prostate gland

NCBI chr 1:79,867,713...79,901,597
Ensembl chr 1:79,863,094...79,901,585

G

histone deacetylase 3

protein:increased expression:prostate gland

NCBI chr 2:143,273,188...143,287,421
Ensembl chr 2:143,273,192...143,287,399

G

hydroxymethylbilane synthase

mRNA:decreased expression:tumor:in matched malignant and non-malignant sample pairs (p = 0.009)

NCBI chr 9:46,300,039...46,308,681
Ensembl chr 9:46,300,050...46,308,868

G

insulin like growth factor 1 receptor

NCBI chr 1:137,383,623...137,691,038
Ensembl chr 1:137,387,825...137,691,058

G

inhibin subunit alpha

DNA:hypermethylation,loss of heterozygosity:promoter,genomic region:significant hypermethylation (P<0.001) in tumors vs nonmalignant controls, LOH at 2q32-36 in 42% of cases

NCBI chr15:121,581,847...121,586,020
Ensembl chr15:121,580,803...121,586,006

G

Jun proto-oncogene, AP-1 transcription factor subunit

protein:increased activation:tumor:nuclear localization in 13/16 (81.25%) of BPH and 31/36 (86.1%) of adenocarcinomas (PCa) with significantly stronger staining in PCa (P=0.006)

NCBI chr 6:153,686,425...153,687,635
Ensembl chr 6:153,685,682...153,687,636

G

MET proto-oncogene, receptor tyrosine kinase

disease_progression

protein:increased expression:primary tumor, metastatic carcinoma (human)

NCBI chr18:29,426,044...29,541,526
Ensembl chr18:29,426,048...29,541,512

G

matrix Gla protein

mRNA:increased expression:primary tumor; mRNA:decreased expression:metastatic tissue:decreased or absent expression in metastases and cell lines from metastatic tumors

NCBI chr 5:57,665,272...57,669,360
Ensembl chr 5:57,665,248...57,669,764

G

marker of proliferation Ki-67

NCBI chr14:137,266,622...137,296,312

G

matrix metallopeptidase 7

NCBI chr 9:33,214,590...33,225,080
Ensembl chr 9:33,214,594...33,225,080

G

NME/NM23 nucleoside diphosphate kinase 1

NCBI chr12:27,416,308...27,435,044
Ensembl chr12:27,416,346...27,436,140

G

platelet derived growth factor subunit B

Ensembl chr 5:8,986,462...9,007,435

G

platelet derived growth factor D

disease_progression

NCBI chr 9:34,388,636...34,621,227
Ensembl chr 9:34,388,643...34,621,244

G

polo like kinase 1

mRNA, protein:increased expression:prostate gland

NCBI chr 3:22,537,814...22,550,901
Ensembl chr 3:22,537,831...22,552,380

G

protein kinase C alpha

NCBI chr12:12,882,287...13,268,647
Ensembl chr12:12,882,064...13,263,554

G

seryl-tRNA synthetase 1

mRNA:decreased expression:prostate gland (human)

NCBI chr 4:110,857,067...110,874,712
Ensembl chr 4:110,857,089...110,874,815

G

S-phase kinase associated protein 2

NCBI chr16:21,463,270...21,500,925
Ensembl chr16:21,463,012...21,509,310

G

serine peptidase inhibitor, Kunitz type 1

disease_progression

protein:decreased expression:prostate gland (human)

NCBI chr 1:130,458,909...130,473,791
Ensembl chr 1:130,458,909...130,473,783

G

secreted phosphoprotein 1

NCBI chr 8:131,077,786...131,085,334
Ensembl chr 8:131,077,786...131,085,340

G

signal transducer and activator of transcription 3

protein:increased activity:prostate gland

PMID:11987152 PMID:18210874

RGD:2291910 RGD:2298538

NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,992

G

signal transducer and activator of transcription 6

protein:increased activity:tumor:significant increase in constitutive activation vs adjacent normal tissue and unrelated normal prostate, by EMSA

NCBI chr 5:22,406,356...22,422,412
Ensembl chr 5:22,406,368...22,421,989

G

transmembrane BAX inhibitor motif containing 6

mRNA:increased expression:prostate gland

NCBI chr 5:15,674,028...15,692,944
Ensembl chr 5:15,674,057...15,692,936

G

tumor protein p73

disease_progression

mRNA, protein:increased expression:prostate gland

NCBI chr 6:65,169,770...65,228,997
Ensembl chr 6:65,182,456...65,228,990

prostate carcinoma in situ

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha-methylacyl-CoA racemase

disease_progression

NCBI chr16:20,005,741...20,023,339
Ensembl chr16:19,956,366...20,023,289

G

apurinic/apyrimidinic endodeoxyribonuclease 1

protein:increased expression, altered localization:prostate, cytoplasm

NCBI chr 7:78,451,845...78,454,938
Ensembl chr 7:78,451,851...78,454,938

G

androgen receptor

CTD Direct Evidence: marker/mechanism

NCBI chr X:53,609,113...53,806,778
Ensembl chr X:53,609,176...53,800,677

G

amphiregulin

protein:increased expression:prostate gland

NCBI chr 8:70,417,935...70,428,106
Ensembl chr 8:70,417,923...70,428,102

G

ATM serine/threonine kinase

protein:increased serine phosphorylation:prostate gland

NCBI chr 9:36,620,656...36,759,555
Ensembl chr 9:36,620,657...36,759,552

G

aurora kinase A

protein:increased expression:prostate gland

PMID:15754349 PMID:16707419

RGD:2293877 RGD:2293883

NCBI chr17:56,954,838...56,972,435

G

aurora kinase B

NCBI chr12:53,410,833...53,426,165
Ensembl chr12:53,410,177...53,423,225

G

BTG anti-proliferation factor 2

protein:decreased expression:prostate gland

NCBI chr 9:64,033,853...64,037,795
Ensembl chr 9:64,031,832...64,035,837

G

coactivator associated arginine methyltransferase 1

protein:increased expression:prostate gland

NCBI chr 2:69,602,121...69,644,862
Ensembl chr 2:69,602,136...69,644,854

G

cyclin D1

mRNA, protein:decreased expression:prostate gland

NCBI chr 2:3,621,242...3,633,380
Ensembl chr 2:3,621,246...3,633,296

G

cyclin E1

mRNA, protein:increased expression:prostate gland

NCBI chr 6:39,919,541...39,933,224
Ensembl chr 6:39,919,624...39,933,363

G

cadherin 1

CTD Direct Evidence: marker/mechanism

NCBI chr 6:18,075,487...18,155,986
Ensembl chr 6:18,075,480...18,155,986

G

cyclin dependent kinase inhibitor 1B

CTD Direct Evidence: therapeutic

PMID:18691549 PMID:20932324

NCBI chr 5:59,731,224...59,735,831
Ensembl chr 5:59,731,206...59,735,831

G

cAMP responsive element binding protein 3 like 4

severity

NCBI chr 4:95,716,530...95,723,959
Ensembl chr 4:95,716,537...95,722,947

G

colony stimulating factor 1 receptor

protein:increased expression:prostate gland

NCBI chr 2:151,102,138...151,130,311
Ensembl chr 2:151,102,147...151,147,633

G

cytochrome P450 19A3

NCBI chr 1:120,476,890...120,556,103
Ensembl chr 1:120,367,667...120,695,899

G

DNA methyltransferase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:68,981,564...69,040,364
Ensembl chr 2:68,981,566...69,029,844

G

estrogen receptor 1

CTD Direct Evidence: marker/mechanism

PMID:16220300 PMID:22025007

NCBI chr 1:14,217,032...14,604,906
Ensembl chr 1:14,217,036...14,493,363

G

estrogen receptor 2

treatment

CTD Direct Evidence: marker/mechanism

PMID:16220300 PMID:22025007

NCBI chr 1:193,823,666...193,907,330
Ensembl chr 1:193,829,560...193,906,565

G

fibroblast growth factor 6

protein:increased expression:prostate gland

NCBI chr 5:65,975,807...65,990,035
Ensembl chr 5:65,975,838...65,990,029

G

fibroblast growth factor 8

NCBI chr14:112,808,215...112,814,225
Ensembl chr14:112,808,162...112,814,248

G

fibroblast growth factor receptor 1

NCBI chr15:48,053,895...48,106,634
Ensembl chr15:48,053,340...48,106,724

G

fibroblast growth factor receptor 2

NCBI chr14:131,183,095...131,285,001
Ensembl chr14:131,181,713...131,289,425

G

fms related receptor tyrosine kinase 1

protein:decreased expression:prostate gland

NCBI chr11:5,620,698...5,797,095
Ensembl chr11:5,621,212...5,795,264

G

frizzled class receptor 4

protein:increased expression:prostate gland

NCBI chr 9:20,714,995...20,721,460
Ensembl chr 9:20,717,344...20,721,460

G

histone deacetylase 1

protein:increased expression:prostate gland

NCBI chr 6:88,749,611...88,785,220
Ensembl chr 6:88,749,634...88,785,411

G

insulin like growth factor 1

protein:increased expression:prostate gland

NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033

G

KRAS proto-oncogene, GTPase

NCBI chr 5:48,508,774...48,546,260
Ensembl chr 5:48,508,811...48,549,358

G

lymphoid enhancer binding factor 1

NCBI chr 8:113,824,511...113,944,078
Ensembl chr 8:113,825,161...113,944,070

G

glutathione S-transferase P-like

NCBI chr 2:4,978,761...4,982,233

G

glutathione S-transferase P-like

CTD Direct Evidence: marker/mechanism

NCBI chr 2:5,005,498...5,009,247

G

LDL receptor related protein 1

protein:increased expression:prostate gland

NCBI chr 5:22,435,636...22,519,276

G

mitogen-activated protein kinase kinase 4

disease_progression

protein:increased expression

NCBI chr12:56,402,029...56,516,217
Ensembl chr12:56,402,075...56,516,238

G

mitogen-activated protein kinase kinase 6

disease_progression

protein:increased expression

NCBI chr12:10,891,445...11,018,617
Ensembl chr12:10,894,966...11,018,641

G

mitogen-activated protein kinase kinase 7

disease_progression

protein:increased expression

NCBI chr 2:71,299,010...71,308,432
Ensembl chr 2:71,298,325...71,308,124

G

metallothionein-2A

CTD Direct Evidence: marker/mechanism

NCBI chr 6:18,645,125...18,646,034
Ensembl chr 6:18,645,153...18,646,033

G

MYC proto-oncogene, bHLH transcription factor

NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,122...12,461,078

G

prohibitin 1

mRNA, protein:increased expression:prostate gland

NCBI chr12:25,596,520...25,609,693
Ensembl chr12:25,596,523...25,609,706

G

Pim-1 proto-oncogene, serine/threonine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr 7:32,788,246...32,793,882
Ensembl chr 7:32,788,291...32,793,878

G

serine protease 8

disease_progression

mRNA, protein:increased expression:prostate gland

NCBI chr 3:17,357,793...17,362,223
Ensembl chr 3:17,357,802...17,362,220

G

phosphatase and tensin homolog

CTD Direct Evidence: marker/mechanism

PMID:18268330 PMID:19081794 PMID:22581815

NCBI chr14:99,929,590...100,021,619

G

prostaglandin-endoperoxide synthase 2

protein:altered localization

NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884

G

RELA proto-oncogene, NF-kB subunit

protein:increased expression:prostate gland

PMID:15570007 PMID:16278667

RGD:2298767 RGD:2298769

NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469

G

retinoid X receptor alpha

protein:decreased expression:prostate

NCBI chr 1:273,698,842...273,797,622
Ensembl chr 1:273,705,505...273,797,620

G

solute carrier family 30 member 4

protein:decreased expression:prostate gland

NCBI chr 1:126,236,971...126,268,102
Ensembl chr 1:126,237,032...126,268,094

G

SMAD family member 4

protein:increased expression:prostate gland

NCBI chr 1:100,521,843...100,633,501
Ensembl chr 1:100,589,850...100,628,029

G

ST14 transmembrane serine protease matriptase

protein:increased expression:prostate gland

NCBI chr 9:56,888,246...56,929,771
Ensembl chr 9:56,888,246...56,929,767

G

serine/threonine kinase 11

NCBI chr 2:77,229,888...77,249,322
Ensembl chr 2:77,230,372...77,249,327

G

TIMP metallopeptidase inhibitor 4

NCBI chr13:68,179,803...68,191,199
Ensembl chr13:68,179,806...68,190,942

G

DNA topoisomerase II beta

CTD Direct Evidence: marker/mechanism

NCBI chr13:12,507,738...12,575,042
Ensembl chr13:12,507,138...12,575,583

G

tumor protein p63

protein:decreased expression:prostate gland
CTD Direct Evidence: marker/mechanism

PMID:17189982 PMID:17982114 PMID:22581815

RGD:2315433 RGD:2315434

NCBI chr13:127,115,990...127,347,082
Ensembl chr13:127,116,105...127,347,068

prostate small cell carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

BRCA2 DNA repair associated

ClinVar Annotator: match by term: Metastatic Prostate Small Cell Carcinoma

PMID:10550133 PMID:10660329 PMID:11597388 PMID:11802209 PMID:15024741 More...

NCBI chr11:8,805,950...8,858,128
Ensembl chr11:8,805,913...8,857,793

Term paths to the root

Path 1
Term	Annotations
disease	15433
disease of anatomical entity	15103
reproductive system disease	3072
reproductive organ cancer	1376
male reproductive organ cancer	807
prostate cancer	803
Familial Prostate Cancer +	68
Prostate Cancer, Somatic	6
Prostate Cancer/Brain Cancer Susceptibility	1
prostate carcinoma +	145
prostate lymphoma	0
prostate malignant phyllodes tumor	0
prostate neuroendocrine neoplasm	0
prostate sarcoma +	0
Path 2
Term	Annotations
disease	15433
disease of anatomical entity	15103
Urogenital Diseases	4865
reproductive system disease	3072
male reproductive system disease	1954
Male Genital Neoplasms	1292
Prostatic Neoplasms	1265
prostate cancer	803
Familial Prostate Cancer +	68
Prostate Cancer, Somatic	6
Prostate Cancer/Brain Cancer Susceptibility	1
prostate carcinoma +	145
prostate lymphoma	0
prostate malignant phyllodes tumor	0
prostate neuroendocrine neoplasm	0
prostate sarcoma +	0

paths to the root