prostate cancer - Ontology Report - Rat Genome Database

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RGD DISEASE ONTOLOGY - ANNOTATIONS

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RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:	prostate cancer	go back to main search page
Accession:	DOID:10283	browse the term
Definition:	A male reproductive organ cancer that is located_in the prostate. (DO)
Synonyms:	exact_synonym:	NGP - new growth of prostate; cancer of prostate; cancer of the prostate; malignant tumor of prostate; malignant tumor of the prostate; prostate cancers; prostatic cancer; tumor of the prostate
	narrow_synonym:	GEN1-RELATED CONDITION; GEN1-RELATED PROSTATE CANCER; PROSTATE CANCER, PROGRESSION AND METASTASIS OF; familial prostate cancer
	related_synonym:	CYP3A4 PROMOTER POLYMORPHISM, Cyp3a4-v; prostate cancer, susceptibility to; prostate cancer, susceptibility to, in African Americans
	xref:	EFO:0000196; ICD10CM:C61; ICD9CM:185; MIM:176807; MONDO:0008315; NCI:C3343; NCI:C7378; ORDO:1331
For additional species annotation, visit the Alliance of Genome Resources.

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Genes (809)

prostate cancer

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily A member 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:2,171,487...2,218,851

G

ATP binding cassette subfamily C member 4 (PEL blood group)

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:73,821,887...74,106,617
Ensembl chr 3:73,821,134...74,106,579

G

ATP binding cassette subfamily E member 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:91,673,359...91,704,774

G

ATP binding cassette subfamily F member 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:5,232,161...5,240,012
Ensembl chr15:5,227,836...5,239,958

G

ATP binding cassette subfamily G member 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:110,522,773...110,537,747
Ensembl chr 1:110,524,900...110,537,735

G

ankyrin repeat and BTB domain containing 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:102,535,469...102,882,227
Ensembl chr11:102,800,591...102,882,388

G

acid phosphatase 3

disease_progression

ISO

PSA/PAP (prostatic acid phosphatase) ratio - a valuable prognostic indicator in men with Stage IV prostate cancer
OMIM:176807 | OMIM:300147 | OMIM:300704 | OMIM:601518 | OMIM:602759 | OMIM:608656 | OMIM:608658 | OMIM:609299 | OMIM:609558 | OMIM:610321 | OMIM:610997 | OMIM:611100 | OMIM:611868 | OMIM:611928 | OMIM:611955 | OMIM:611958 | OMIM:611959

PMID:16024648 PMID:17991541

RGD:2301054 RGD:2301055

NCBI chr15:57,887,528...57,934,851
Ensembl chr15:57,887,365...57,934,707

G

acrosomal vesicle protein 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:116,812,667...116,821,625
Ensembl chr 1:116,812,726...116,821,073

G

acyl-CoA synthetase long chain family member 3

disease_progression
treatment

ISO

NCBI chr10:108,787,341...108,867,523
Ensembl chr10:108,787,061...108,869,042

G

ADAM metallopeptidase with thrombospondin type 1 motif 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:20,793,392...21,068,712
Ensembl chr 7:20,793,399...21,048,515

G

adenosine deaminase tRNA specific 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:61,083,029...61,108,751
Ensembl chr 5:61,082,819...61,108,330

G

ADRM1 26S proteasome ubiquitin receptor

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:1,930,281...1,936,323
Ensembl chr 2:1,925,382...1,936,393

G

adenylosuccinate lyase

severity

ISO

protein:increased activity:tumor (human)

NCBI chr19:22,920,971...22,940,468

G

alpha fetoprotein

ISO

protein:increased expression:serum

NCBI chr 7:21,904,225...21,924,105
Ensembl chr 7:21,905,154...21,924,092

G

ArfGAP with GTPase domain, ankyrin repeat and PH domain 2

ISO

protein:increased expression:prostate

NCBI chr11:53,638,722...53,655,826
Ensembl chr11:53,640,079...53,651,913

G

advanced glycosylation end-product specific receptor

ISO

mRNA:increased expression:prostate gland (human)

NCBI chr17:39,847,343...39,851,288
Ensembl chr17:39,847,759...39,851,127

G

1-acylglycerol-3-phosphate O-acyltransferase 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:1,511,063...1,525,146
Ensembl chr12:1,511,124...1,525,440

G

aryl hydrocarbon receptor repressor

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:220,523...329,973
Ensembl chr 4:243,026...326,722

G

apoptosis inducing factor mitochondria associated 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr X:105,383,408...105,419,146
Ensembl chr X:105,382,693...105,419,095

G

A-kinase anchoring protein 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:36,275,287...36,313,612
Ensembl chr16:36,275,209...36,306,012

G

aldo-keto reductase family 1 member C3

disease_progression

ISO

protein:increased expression:epithelium:
ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:24571686

NCBI chr 9:5,237,176...5,254,772

G

AKT serine/threonine kinase 1

severity

ISO

DNA:SNPs:5' utr, intron: (rs1130214, rs2494738) (human)

NCBI chr24:82,704,087...82,730,711
Ensembl chr24:82,704,068...82,727,698

G

AKT serine/threonine kinase 2

ISO

DNA:SNP: :rs7254617 (human)

NCBI chr 6:34,688,585...34,740,458
Ensembl chr 6:34,690,462...34,720,781

G

AKT serine/threonine kinase 3

severity

ISO

DNA:SNP: :rs2125230 (human)

NCBI chr25:80,509,701...80,878,792
Ensembl chr25:80,515,168...80,816,018

G

aldehyde dehydrogenase 5 family member A1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:47,712,785...47,746,198
Ensembl chr17:47,709,888...47,745,830

G

aldehyde dehydrogenase 9 family member A1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:63,184,220...63,223,865

G

arachidonate 12-lipoxygenase, 12S type

disease_progression

ISO

mRNA:increased expression:prostate gland

NCBI chr16:6,355,795...6,370,051
Ensembl chr16:6,356,058...6,369,738

G

adenosylmethionine decarboxylase 1

ISO

protein:increased expression:prostate

NCBI chr13:62,977,659...62,999,150

G

angiogenin

ISO

PMID:11948474 PMID:19276260

RGD:2325697 RGD:2325707

NCBI chr29:21,215,985...21,226,927

G

ankyrin repeat domain 12

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr18:68,055,330...68,189,543
Ensembl chr18:68,121,005...68,187,751

G

anoctamin 9

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:235,246...253,391
Ensembl chr 1:235,702...249,990

G

annexin A7

ISO

protein:decreased expression:prostate gland

NCBI chr 9:57,863,482...57,900,972
Ensembl chr 9:57,863,546...57,900,324

G

adaptor related protein complex 3 subunit beta 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr 4:72,225,658...72,524,971
Ensembl chr 4:72,225,599...72,524,933

G

APC regulator of WNT signaling pathway

disease_progression

ISO

OMIM:176807 | OMIM:300147 | OMIM:300704 | OMIM:601518 | OMIM:602759 | OMIM:608656 | OMIM:608658 | OMIM:609299 | OMIM:609558 | OMIM:610321 | OMIM:610997 | OMIM:611100 | OMIM:611868 | OMIM:611928 | OMIM:611955 | OMIM:611958 | OMIM:611959

NCBI chr23:15,992,437...16,135,117
Ensembl chr23:16,042,287...16,137,067

G

androgen receptor

no_association
treatment

ISO

african-american men
ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: Prostate cancer

PMID:1307250 PMID:1631125 PMID:1779964 PMID:2594783 PMID:7671849 More...

RGD:10043311 RGD:1578686

NCBI chr X:57,380,587...57,553,613
Ensembl chr X:57,380,611...57,546,776

G

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr23:44,280,010...44,308,046
Ensembl chr23:44,279,727...44,306,272

G

Rho GTPase activating protein 20

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:101,920,074...102,047,171
Ensembl chr 1:101,921,839...102,046,751

G

Rho guanine nucleotide exchange factor 15

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr16:7,674,190...7,687,129
Ensembl chr16:7,674,577...7,687,834

G

Rho guanine nucleotide exchange factor 25

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:53,518,295...53,525,428
Ensembl chr11:53,518,397...53,525,068

G

Rho guanine nucleotide exchange factor 40

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr29:21,543,572...21,563,229
Ensembl chr29:21,546,064...21,562,558

G

armadillo repeat containing 12

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:36,368,789...36,392,119
Ensembl chr17:36,368,832...36,388,749

G

cAMP regulated phosphoprotein 21

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:80,048,078...80,204,843
Ensembl chr15:80,089,657...80,204,314

G

acid sensing ion channel subunit 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:26,547,878...27,674,909

G

aspartic peptidase retroviral like 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:37,019,454...37,051,341
Ensembl chr14:37,158,086...37,159,117
Ensembl chr14:37,158,086...37,159,117

G

activating transcription factor 3

disease_progression
treatment

ISO

PMID:26522727 PMID:26944919

RGD:13506816 RGD:13506817

NCBI chr25:16,910,312...16,922,598

G

autophagy related 13

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:18,651,872...18,712,395
Ensembl chr 1:18,652,998...18,712,482

G

atlastin GTPase 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:10,569,052...10,611,518
Ensembl chr 1:10,569,235...10,611,323

G

ATM serine/threonine kinase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23807571 PMID:25614872 PMID:25741868 PMID:28492532

NCBI chr 1:99,653,208...99,786,889
Ensembl chr 1:99,653,139...99,791,520

G

ATPase Na+/K+ transporting subunit alpha 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054

G

ATPase plasma membrane Ca2+ transporting 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:25,602,857...25,716,385
Ensembl chr25:25,602,715...25,661,553

G

ATPase H+ transporting V0 subunit a1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:63,754,523...63,818,537
Ensembl chr16:63,753,521...63,816,551

G

alpha-2-glycoprotein 1, zinc-binding

ISO

protein:increased expression:serum

NCBI chr28:13,104,262...13,120,329
Ensembl chr28:13,104,323...13,120,363

G

beta-1,3-galactosyltransferase 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:52,792,505...53,368,536
Ensembl chr10:53,366,522...53,367,499

G

BRISC and BRCA1 A complex member 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:79,277,238...79,732,996
Ensembl chr14:79,289,043...79,732,891

G

BAG cochaperone 1

ISO

DNA, protein:amplification, increased expression:prostate gland

NCBI chr12:47,006,177...47,016,177

G

BCL2 associated X, apoptosis regulator

ISO

PMID:17575222 PMID:18444130

RGD:1643354 RGD:2292907

NCBI chr 6:42,186,028...42,193,105

G

BCL2 apoptosis regulator

disease_progression

ISO

PMID:16984224 PMID:17850375 PMID:18084610

RGD:2292512 RGD:2293015 RGD:2293017

NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895

G

bone gamma-carboxyglutamate protein

ISO

NCBI chr20:7,623,716...7,626,353
Ensembl chr20:7,623,883...7,624,812

G

BICRA like chromatin remodeling complex associated protein

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:29,283,287...29,402,201
Ensembl chr17:29,283,150...29,331,259

G

BCL2 interacting killer

ISO

NCBI chr19:25,632,837...25,658,951
Ensembl chr19:25,652,945...25,658,541

G

baculoviral IAP repeat containing 5

severity

ISO

mRNA:increased expression:prostate gland

PMID:17804712 PMID:18336887

RGD:2293091 RGD:2293100

NCBI chr16:70,226,824...70,237,000

G

bridge-like lipid transfer protein family member 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:22,383,058...22,414,910
Ensembl chr16:22,383,677...22,412,701

G

bone morphogenetic protein 2

disease_progression
susceptibility

ISO

DNA:amplification:prostate gland

PMID:15042598 PMID:17656261

RGD:2289030 RGD:2299981

NCBI chr 2:31,349,394...31,361,227
Ensembl chr 2:31,348,808...31,360,901

G

bone morphogenetic protein 6

ISO

protein:increased expression:prostate

NCBI chr17:64,279,243...64,436,356
Ensembl chr17:64,280,609...64,435,382

G

bone morphogenetic protein 7

susceptibility

ISO

protein:decreased expression:prostate gland
DNA:amplification:prostate gland

PMID:15861517 PMID:17656261

RGD:2289030 RGD:2289031

NCBI chr 2:6,856,396...6,954,948
Ensembl chr 2:6,856,453...6,954,944

G

BCL2 interacting protein 5

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:35,792,013...35,807,059
Ensembl chr17:35,792,115...35,805,471

G

BRCA1 DNA repair associated

no_association
severity

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate
DNA:deletions: :185_186del,1294_1333del,3875_3878del

PMID:10398279 PMID:12491487 PMID:15235020 PMID:15447980 PMID:16267036 More...

RGD:2289042 RGD:734657

NCBI chr16:63,162,827...63,243,928

G

BRCA2 DNA repair associated

disease_progression

ISO

DNA:mutation
ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: Prostate cancer

RGD
ClinVar
OMIM

PMID:1 PMID:278235 PMID:1772447 PMID:2200631 PMID:2661312 More...

NCBI chr 3:11,070,086...11,155,257
Ensembl chr 3:11,071,682...11,155,213

G

BRF2 general transcription factor IIIB subunit

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:25741868

NCBI chr 8:35,879,762...35,885,572
Ensembl chr 8:35,880,373...35,885,485

G

BTB domain containing 16

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:115,005,070...115,073,976
Ensembl chr 9:115,010,795...115,073,899

G

C2 calcium dependent domain containing 6

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

G

complement C3a receptor 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:8,128,192...8,135,517
Ensembl chr11:8,128,620...8,130,062

G

complement C5

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:18,525,855...18,624,048
Ensembl chr12:18,525,880...18,623,636

G

calcineurin binding protein 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:7,127,370...7,289,054
Ensembl chr19:7,127,401...7,289,050

G

calcium voltage-gated channel subunit alpha1 D

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr22:14,868,459...15,195,002
Ensembl chr22:15,027,565...15,197,101

G

cell adhesion molecule 1

ISO

DNA:hypermethylation:promoter

NCBI chr 1:106,539,262...106,876,397
Ensembl chr 1:106,539,136...106,606,637

G

cell adhesion molecule 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:4,746,751...4,777,321
Ensembl chr20:4,747,800...4,777,298

G

calcium dependent secretion activator

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr22:23,471,616...23,948,694

G

calcium/calmodulin dependent protein kinase II inhibitor 1

disease_progression

ISO

mRNA, protein:decreased expression:prostate gland

PMID:25003983 PMID:31762801

RGD:18337271 RGD:18337280

NCBI chr20:112,064,718...112,068,505
Ensembl chr20:112,065,581...112,067,256

G

cullin associated and neddylation dissociated 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:62,923,198...62,968,789
Ensembl chr11:62,922,885...62,966,994

G

calpain 6

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:99,052,100...99,077,508
Ensembl chr X:99,051,989...99,077,302

G

calcium/calmodulin dependent serine protein kinase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:38,704,623...39,121,309

G

caspase 3

ISO

NCBI chr 7:130,589,592...130,610,845
Ensembl chr 7:130,591,166...130,610,899

G

calcium sensing receptor

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr22:58,579,640...58,612,142
Ensembl chr22:58,578,396...58,604,756

G

caveolin 1

disease_progression

ISO

protein:increased expression:serum
DNA:hypermethylation:promoter

PMID:11170154 PMID:14506154 PMID:15948133

RGD:2289104 RGD:2289109 RGD:2289112

NCBI chr21:85,222,724...85,258,562
Ensembl chr21:85,222,879...85,258,627

G

chromobox 1

ISO

protein:increased expression:prostate:

NCBI chr16:68,471,298...68,508,180

G

chromobox 3

ISO

protein:increased expression:prostate:

NCBI chr21:32,154,707...32,166,843
Ensembl chr21:32,155,839...32,166,114

G

chromobox 5

ISO

protein:increased expression:prostate:

NCBI chr11:50,350,440...50,396,595
Ensembl chr11:50,353,638...50,396,608

G

chromobox 7

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:21,776,618...21,798,525
Ensembl chr19:21,775,931...21,798,309

G

chibby 1, beta catenin antagonist

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:21,318,124...21,335,973
Ensembl chr19:21,318,164...21,338,920

G

coiled-coil domain containing 171

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:63,594,745...64,044,086
Ensembl chr12:63,753,934...64,042,872

G

cyclin A1

disease_progression

ISO

human gene, mouse model

NCBI chr 3:14,979,775...14,992,609
Ensembl chr 3:14,982,392...14,993,562

G

cyclin B1

ISO

NCBI chr 4:65,265,798...65,276,465
Ensembl chr 4:65,265,844...65,277,085

G

cyclin D1

ISO

NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357

G

cyclin D2

disease_progression

ISO

DNA, mRNA:hyperymethylation, decreased expression:promoter, prostate gland

PMID:16322291 PMID:17016690

RGD:151665170 RGD:2289151

NCBI chr11:4,307,419...4,339,003
Ensembl chr11:4,307,401...4,333,661

G

cyclin D3

disease_progression

ISO

NCBI chr17:30,107,236...30,228,449
Ensembl chr17:30,221,598...30,227,452

G

CD2 molecule

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:16,954,925...16,970,066
Ensembl chr20:16,953,811...16,970,044

G

CD244 molecule

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:3,103,226...3,138,322

G

CD2 associated protein

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:24,664,245...24,815,786
Ensembl chr17:24,663,872...24,815,829

G

CD44 molecule (IN blood group)

disease_progression

ISO

DNA:hypermethylation:prostate gland

NCBI chr 1:30,039,854...30,132,646
Ensembl chr 1:30,039,749...30,132,416

G

CD55 molecule (Cromer blood group)

ISO

PMID:16533428 PMID:18288643

RGD:2326167 RGD:2326168

NCBI chr25:22,055,138...22,092,472
Ensembl chr25:22,073,629...22,092,173

G

CD82 molecule

disease_progression

ISO

protein:decreased expression:prostate gland

NCBI chr 1:20,736,216...20,793,943
Ensembl chr 1:20,735,287...20,763,160

G

cell division cycle 25A

ISO

NCBI chr22:9,534,114...9,564,927
Ensembl chr22:9,534,053...9,564,741

G

cell division cycle 25B

ISO

protein:increased expression:prostate gland

NCBI chr 2:34,482,709...34,493,737
Ensembl chr 2:34,483,771...34,494,071

G

cell division cycle 25C

ISO

mRNA, protein:alternative form, increased expression, increased activity:prostate gland

PMID:12896904 PMID:16000564 PMID:16140946 PMID:17460776

RGD:2756028 RGD:2774210 RGD:2776427 RGD:4105453

NCBI chr23:40,960,154...41,013,016
Ensembl chr23:40,960,572...41,006,984

G

cadherin 1

disease_progression
susceptibility

ISO

protein:decreased expression:prostate gland
ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: PROSTATE CANCER, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Prostate cancer
DNA:polymorphism:promoter:-160C>A (human)

PMID:1722187 PMID:2403327 PMID:2449335 PMID:8075649 PMID:9537325 More...

RGD:2289487 RGD:2289493

NCBI chr 5:58,578,244...58,679,677
Ensembl chr 5:58,578,146...58,679,541

G

cadherin 13

disease_progression

ISO

DNA:hypermethylation:promoter

NCBI chr 5:68,048,655...69,213,102
Ensembl chr 5:68,451,894...69,211,534

G

cadherin 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr 5:58,717,600...58,775,033
Ensembl chr 5:58,717,597...58,775,339

G

cyclin dependent kinase 13

ISO

mRNA,protein:increased expression:prostate:

NCBI chr21:18,551,273...18,688,889
Ensembl chr21:18,553,446...18,688,525

G

cyclin dependent kinase 2

ISO

NCBI chr11:51,905,085...51,910,209
Ensembl chr11:51,905,115...51,909,907

G

cyclin dependent kinase 4

ISO

NCBI chr11:53,661,877...53,665,688
Ensembl chr11:53,659,336...53,664,861

G

cyclin dependent kinase inhibitor 1A

ISO

NCBI chr17:35,445,668...35,454,334
Ensembl chr17:35,445,223...35,454,342

G

cyclin dependent kinase inhibitor 2A

disease_progression

ISO

protein:increased expression:prostate gland
DNA:hypermethylation:promoter

PMID:16483154 PMID:16799475

RGD:2289684 RGD:2289685

G

CDKN2A interacting protein

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:129,429,535...129,433,687
Ensembl chr 7:129,429,533...129,435,285

G

cyclin dependent kinase inhibitor 2B

disease_progression

ISO

protein:increased expression:prostate gland

G

ceramide synthase 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr29:18,883,532...19,016,790
Ensembl chr29:18,929,866...18,974,662

G

cilia and flagella associated protein 43

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:97,179,767...97,283,267
Ensembl chr 9:97,179,647...97,283,225

G

cilia and flagella associated protein 65

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:104,902,365...104,946,934
Ensembl chr10:104,902,401...104,944,401

G

ChaC glutathione specific gamma-glutamylcyclotransferase 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr26:42,038,751...42,041,836
Ensembl chr26:42,038,528...42,041,760

G

chromatin assembly factor 1 subunit B

disease_progression

ISO

protein:increased expression:prostate:
ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:19309489 PMID:23265383

NCBI chr 2:80,379,637...80,409,626
Ensembl chr 2:80,380,425...80,409,687

G

chromodomain helicase DNA binding protein 1

ISO

DNA:deletions: :

NCBI chr23:2,433,694...2,507,334
Ensembl chr23:2,432,461...2,507,704

G

chromodomain helicase DNA binding protein 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr29:11,436,170...11,579,468
Ensembl chr29:11,450,799...11,579,594

G

checkpoint kinase 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:116,768,141...116,809,557
Ensembl chr 1:116,767,944...116,801,371

G

checkpoint kinase 2

susceptibility

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: Prostate cancer | ClinVar Annotator: match by term: Prostate cancer, susceptibility to
DNA:mutations: :multiple

OMIM
ClinVar
RGD

PMID:3313277 PMID:9536098 PMID:10617473 PMID:11053450 PMID:11298456 More...

NCBI chr19:11,567,529...11,621,180
Ensembl chr19:11,567,528...11,604,792

G

chromogranin A

susceptibility

ISO

DNA:missense mutation:cds:p.E264D (human)

NCBI chr24:70,663,040...70,675,827
Ensembl chr24:70,663,298...70,677,116

G

chromogranin B

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:32,210,079...32,224,123
Ensembl chr 2:32,209,433...32,224,204

G

cysteine rich hydrophobic domain 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:63,124,857...63,244,752
Ensembl chr X:63,124,918...63,241,072

G

component of inhibitor of nuclear factor kappa B kinase complex

ISO

protein:increased serine phosphorylation:prostate gland

NCBI chr 9:93,219,374...93,263,077
Ensembl chr 9:93,219,383...93,262,700

G

cytoskeleton associated protein 5

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:18,504,588...18,584,635
Ensembl chr 1:18,484,372...18,586,623

G

CLPTM1 like

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:1,140,272...1,162,663
Ensembl chr 4:1,140,132...1,162,898

G

cyclic nucleotide gated channel subunit alpha 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr27:2,273,540...2,313,083
Ensembl chr27:2,293,765...2,312,761

G

ciliary neurotrophic factor receptor

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:46,017,992...46,068,187
Ensembl chr12:46,030,203...46,069,944

G

component of oligomeric golgi complex 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:48,426,303...48,441,274
Ensembl chr16:48,423,212...48,441,227

G

collagen type I alpha 1 chain

ISO

ClinVar Annotator: match by term: Prostate cancer

PMID:17211858 PMID:23265383 PMID:25741868 PMID:28492532

NCBI chr16:43,134,648...43,152,313
Ensembl chr16:43,134,779...43,150,930

G

collagen type XXIV alpha 1 chain

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:47,260,635...47,650,408
Ensembl chr20:47,261,261...47,649,269

G

collagen type V alpha 1 chain

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:3,301,643...3,507,300
Ensembl chr12:3,301,175...3,459,607

G

catechol-O-methyltransferase

no_association
disease_progression
susceptibility

ISO

DNA:polymorphism: :p.V158M
DNA:polymorphism:cds

PMID:16126332 PMID:16492910 PMID:17507624

RGD:2289718 RGD:2289719 RGD:2289720

NCBI chr19:5,775,829...5,803,260
Ensembl chr19:5,773,225...5,785,422

G

COP9 signalosome subunit 6

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr28:12,986,194...12,989,189
Ensembl chr28:12,986,346...12,989,174

G

corin, serine peptidase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr27:2,407,451...2,662,855
Ensembl chr27:2,408,219...2,662,279

G

carboxypeptidase A6

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:63,281,059...63,590,016
Ensembl chr 8:63,281,180...63,374,824

G

cleavage and polyadenylation specific factor 7

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:12,417,452...12,445,984
Ensembl chr 1:12,417,490...12,446,527

G

CREB regulated transcription coactivator 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr29:9,223,410...9,341,576
Ensembl chr29:9,223,409...9,341,514

G

cone-rod homeobox

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:41,125,912...41,133,478
Ensembl chr 6:41,126,125...41,132,951

G

CUB and Sushi multiple domains 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:98,708,384...99,358,093
Ensembl chr20:98,936,373...99,352,601

G

catenin alpha 1

disease_progression

ISO

protein:decreased expression:prostate gland

PMID:16334164 PMID:17639504

RGD:2289791 RGD:2289793

NCBI chr23:41,423,504...41,599,458
Ensembl chr23:41,447,675...41,600,190

G

catenin beta 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:9927029 PMID:23265383

NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949

G

cathepsin E

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:23,318,421...23,333,885
Ensembl chr25:23,319,248...23,332,980

G

cortactin binding protein 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr21:86,376,005...86,539,662
Ensembl chr21:86,376,011...86,527,223

G

C-X-C motif chemokine ligand 12

ameliorates

ISO

human cells in mouse model

NCBI chr 9:40,005,580...40,020,513
Ensembl chr 9:40,011,439...40,020,494

G

C-X-C motif chemokine receptor 4

ameliorates

ISO

human cells in mouse model

NCBI chr10:20,336,470...20,340,308
Ensembl chr10:20,336,247...20,340,309

G

cytochrome P450 family 17 subfamily A member 1

ISO

NCBI chr 9:95,870,098...95,877,345
Ensembl chr 9:95,866,908...95,877,180

G

cytochrome P450 family 1 subfamily A member 1

ISO

NCBI chr26:8,753,236...8,759,378
Ensembl chr26:8,753,327...8,759,384

G

DAB2 interacting protein

treatment

ISO

human cells in mouse model

NCBI chr12:17,802,030...18,017,648
Ensembl chr12:17,801,831...17,830,890

G

death domain associated protein

disease_progression

ISO

NCBI chr17:38,754,227...38,758,714
Ensembl chr17:38,754,280...38,759,071

G

dachsous cadherin-related 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:100,770,541...101,036,985

G

DExD-box helicase 50

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:62,378,977...62,424,108
Ensembl chr 9:62,377,491...62,424,006

G

DExD/H-box helicase 60

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:114,474,678...114,578,749
Ensembl chr 7:114,474,680...114,578,563

G

DExD/H-box 60 like

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:114,611,177...114,727,737
Ensembl chr 7:114,610,288...114,727,734

G

DEAF1 transcription factor

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr 1:487,497...510,440

G

diacylglycerol O-acyltransferase 2 like 6

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:60,018,508...60,048,540
Ensembl chr X:60,041,748...60,047,814

G

DiGeorge syndrome critical region gene 6 like

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:2,436,534...2,441,930

G

dihydrodiol dehydrogenase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:42,170,856...42,180,973
Ensembl chr 6:42,170,873...42,181,015

G

DExH-box helicase 29

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:51,491,356...51,543,889
Ensembl chr 4:51,491,598...51,543,774

G

DIS3 like exosome 3'-5' exoribonuclease

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr26:17,217,316...17,258,356
Ensembl chr26:17,216,558...17,257,942

G

dihydrolipoamide S-acetyltransferase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:103,379,165...103,419,585
Ensembl chr 1:103,380,426...103,420,386

G

delta like canonical Notch ligand 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:97,928,480...97,936,594
Ensembl chr13:97,928,634...97,936,589

G

dynein axonemal heavy chain 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:19,068,468...19,274,958
Ensembl chr 5:19,068,515...19,279,417

G

dynein axonemal heavy chain 8

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:33,110,149...33,427,553
Ensembl chr17:33,110,289...33,419,519

G

dynein axonemal heavy chain 9

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:10,947,254...11,316,414
Ensembl chr16:10,948,014...11,317,291

G

DnaJ heat shock protein family (Hsp40) member C3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:25466870 PMID:28940199

NCBI chr 3:74,474,643...74,582,942
Ensembl chr 3:74,474,548...74,579,048

G

DnaJ heat shock protein family (Hsp40) member C6

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:22563501 PMID:23211418 PMID:26528954 PMID:28492532

NCBI chr20:67,661,187...67,824,822
Ensembl chr20:67,660,680...67,809,086

G

DNA methyltransferase 1

disease_progression

ISO

protein:increased expression:nucleus:

NCBI chr 6:9,199,006...9,263,890
Ensembl chr 6:9,199,003...9,263,607

G

dedicator of cytokinesis 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr23:71,866,196...72,299,066
Ensembl chr23:71,866,251...72,299,056

G

dedicator of cytokinesis 5

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:23,310,524...23,540,174
Ensembl chr 8:23,310,673...23,540,478

G

diphthamide biosynthesis 7

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:633,517...651,892

G

developmental pluripotency associated 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr22:71,435,945...71,446,490
Ensembl chr22:71,435,925...71,446,110

G

dihydropyrimidine dehydrogenase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:35,376,738...36,215,388
Ensembl chr20:35,377,266...36,215,679

G

DS cell adhesion molecule like 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:108,801,895...109,167,011
Ensembl chr 1:108,802,452...108,906,272

G

dual specificity phosphatase 1

disease_progression

ISO

NCBI chr23:74,931,421...74,934,510
Ensembl chr23:74,929,863...74,934,532

G

dymeclin

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr18:31,513,665...31,902,064
Ensembl chr18:31,513,735...31,901,811

G

E2F transcription factor 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:37,968,541...37,980,461
Ensembl chr 2:37,968,556...37,980,326

G

E2F transcription factor 3

disease_progression

ISO

PMID:15184867 PMID:17701752 PMID:25017995

RGD:13504717 RGD:13504729 RGD:13504730

NCBI chr17:51,714,052...51,805,827

G

E2F transcription factor 5

ISO

mRNA,protein:increased expression:prostate:

NCBI chr 8:80,542,390...80,587,888
Ensembl chr 8:80,542,580...80,587,226

G

ELL associated factor 2

ISO

protein:decreased expression:prostate gland

NCBI chr22:58,966,640...59,025,158
Ensembl chr22:58,974,409...59,025,143

G

eukaryotic translation elongation factor 2

ISO

protein:increased expression:prostate (human)

NCBI chr 6:3,733,056...3,742,526
Ensembl chr 6:3,732,425...3,742,826

G

EF-hand calcium binding domain 6

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:26,023,566...26,327,309
Ensembl chr19:26,023,643...26,295,493

G

epidermal growth factor receptor

ISO

NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239

G

eukaryotic translation initiation factor 3 subunit H

disease_progression

ISO

DNA:amplification
mRNA:increased expression:prostate gland

PMID:10362802 PMID:11733359

RGD:2289901 RGD:2289902

NCBI chr 8:111,283,184...111,390,835

G

eukaryotic translation initiation factor 4 gamma 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:111,381,420...111,747,248
Ensembl chr20:111,469,837...111,747,416

G

elastin microfibril interfacer 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:80,531,973...80,539,820

G

endoglin

severity

ISO

protein:increased expression:tumor, vasculature (human)

NCBI chr12:10,274,705...10,315,715
Ensembl chr12:10,275,064...10,315,040

G

enolase 2

ISO

NCBI chr11:6,945,243...6,954,959
Ensembl chr11:6,945,413...6,957,304

G

ecto-NOX disulfide-thiol exchanger 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:21,339,684...21,909,377
Ensembl chr 3:21,339,690...21,545,310

G

ectonucleotide pyrophosphatase/phosphodiesterase 7

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:71,693,148...71,701,517
Ensembl chr16:71,693,851...71,699,926

G

ectonucleoside triphosphate diphosphohydrolase 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr22:1,881,640...1,923,708
Ensembl chr22:1,882,978...1,923,837

G

endosomal transmembrane epsin interactor 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:80,421,600...80,485,566
Ensembl chr12:80,421,683...80,484,918

G

E1A binding protein p300

disease_progression

ISO

NCBI chr19:23,634,132...23,726,095
Ensembl chr19:23,634,571...23,724,979

G

EPH receptor B1

susceptibility

ISO

DNA:SNPs,haplptype:multiple

NCBI chr15:55,144,178...55,592,252
Ensembl chr15:55,143,630...55,589,862

G

epithelial stromal interaction 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:20,955,649...21,128,997
Ensembl chr 3:21,022,117...21,128,503

G

erb-b2 receptor tyrosine kinase 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:66,435,488...66,464,993
Ensembl chr16:66,434,251...66,464,952

G

erb-b2 receptor tyrosine kinase 3

disease_progression

ISO

protein:altered localization:nucleus
ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:17532856 PMID:23265383

NCBI chr11:52,020,912...52,043,809
Ensembl chr11:52,021,058...52,044,028

G

erb-b2 receptor tyrosine kinase 4

ISO

protein:increased expression:prostate gland

NCBI chr10:97,099,090...98,281,697

G

erbb2 interacting protein

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:62,123,012...62,267,832
Ensembl chr 4:62,182,705...62,268,617

G

ERCC excision repair 2, TFIIH core complex helicase subunit

susceptibility

ISO

DNA:missense mutation:cds:p.D312N (human)
DNA:polymorphism:exon:p.R156R(human)

PMID:17695467 PMID:24649009

RGD:5688739 RGD:8657136

NCBI chr 6:38,804,296...38,823,229
Ensembl chr 6:38,801,423...38,823,073

G

estrogen receptor 1

susceptibility
severity
disease_progression

ISO

DNA:repeat
DNA:hypermethylation:promoter
mRNA:increased expression:prostate gland

PMID:17908481 PMID:17922863 PMID:18006911

RGD:2290020 RGD:2290022 RGD:2290023

NCBI chr13:79,153,418...79,554,552
Ensembl chr13:79,270,265...79,554,549

G

estrogen receptor 2

susceptibility

ISO

DNA:snps, haplotype:multiple (human)

NCBI chr24:41,426,333...41,513,802
Ensembl chr24:41,447,224...41,512,486

G

exocyst complex component 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:25741868

NCBI chr17:71,463,836...71,668,429
Ensembl chr17:71,473,962...71,670,095

G

EYA transcriptional coactivator and phosphatase 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:66,902,961...67,238,149
Ensembl chr 8:66,902,972...67,060,567

G

enhancer of zeste 2 polycomb repressive complex 2 subunit

severity

ISO

protein:increased expression:prostate gland (human)

NCBI chr21:117,380,518...117,515,224
Ensembl chr21:117,380,361...117,421,573

G

coagulation factor V

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:59,465,610...59,539,022
Ensembl chr25:59,466,378...59,538,872

G

fatty acid binding protein 5

ISO

mRNA:increased expression:prostate (human)

NCBI chr 8:76,696,899...76,701,459

G

family with sequence similarity 13 member C

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:71,898,392...72,038,998
Ensembl chr 9:71,923,477...72,040,371

G

family with sequence similarity 83 member C

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:56,191,896...56,199,786
Ensembl chr 2:56,192,688...56,198,758

G

FA complementation group A

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:10094191 PMID:24728327 PMID:25741868 PMID:26181256 PMID:28492532 More...

NCBI chr 5:75,073,161...75,149,110
Ensembl chr 5:75,073,358...75,148,591

G

failed axon connections homolog, metaxin like GST domain containing

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:74,525,175...74,596,948
Ensembl chr13:74,525,691...74,594,703

G

F-box DNA helicase 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:6,001,071...6,047,512
Ensembl chr 9:6,013,908...6,047,753

G

fibrillin 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr23:31,204,652...31,476,677
Ensembl chr23:31,204,391...31,475,820

G

F-box and leucine rich repeat protein 5

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr27:34,575,889...34,682,308
Ensembl chr27:34,580,426...34,625,036

G

FYVE, RhoGEF and PH domain containing 1

ISO

protein:increased expression:prostate gland (human)

NCBI chr X:50,554,648...50,609,437
Ensembl chr X:50,556,168...50,583,010

G

FYVE, RhoGEF and PH domain containing 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:35,112,453...35,136,161
Ensembl chr17:35,112,815...35,136,017

G

fibroblast growth factor 7

ISO

mRNA:increased expression:prostate gland stroma, hormone insensitive tumors

NCBI chr26:33,802,349...33,867,743
Ensembl chr26:33,802,328...33,867,333

G

fibroblast growth factor receptor 1

disease_progression

ISO

NCBI chr 8:36,426,116...36,485,683
Ensembl chr 8:36,427,110...36,485,508

G

fibroblast growth factor receptor 2

no_association
disease_progression

ISO

DNA:mutation,polymorphism:exons:no mutations or polymorphisms found in patient or cell line DNA to explain changes in expression seen in other studies
mRNA:splice variant::shift from Fgfr2IIIb to Fgfr2IIIc in malignancy, restoration of Fgfr2IIIb slows growth
mRNA:increased expression:prostate gland
mRNA:alternative form:prostate:switch from isoform IIIb to IIIc
mRNA:decreased expression:prostate:isoforms IIIb and IIIc, decrease in IIIb associated with progression to androgen-independence

PMID:9285567 PMID:9537256 PMID:11069376 PMID:11170144 PMID:12111699

RGD:2289086 RGD:2289728 RGD:2289746 RGD:2289845 RGD:2289859

NCBI chr 9:114,234,344...114,354,736
Ensembl chr 9:114,234,250...114,354,704

G

fibroblast growth factor receptor 4

disease_progression

ISO

DNA:SNP:exon 9: 288G>A, p.G388R (human)

NCBI chr23:79,095,031...79,106,018
Ensembl chr23:79,097,429...79,105,456

G

FHF complex subunit HOOK interacting protein 1B

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:58,592,828...58,625,732
Ensembl chr 1:58,592,886...58,626,272

G

fragile histidine triad diadenosine triphosphatase

ISO

DNA:SNP:intron:increased risk in carriers of minor allele of SNP rs760317
DNA:hypermethylation:promoter:methylation percentage 15% in tumors vs no methylation in nonmalignant prostate
DNA:SNP:intron:reduced risk in carriers of minor allele of SNP rs760317

PMID:11839671 PMID:15705877 PMID:17548701

RGD:2289869 RGD:2289878 RGD:2289896

NCBI chr22:21,006,010...22,474,056

G

fms related receptor tyrosine kinase 3

ISO

NCBI chr 3:7,117,579...7,222,600
Ensembl chr 3:7,116,947...7,222,849

G

forkhead box O1

disease_progression

ISO

mRNA:decreased expression:tumor:lower in high versus low Gleason score tumors, also lower in tumor vs adjacent normal tissue (p<0.05 compared to at least one housekeeping gene)

NCBI chr 3:18,916,849...19,027,776
Ensembl chr 3:18,920,651...19,027,707

G

forkhead box O3

ISO

mRNA:decreased expression:tumor:lower in tumor vs adjacent normal tissue (p<0.05 compared to at least one housekeeping gene)

NCBI chr13:65,175,764...65,303,107
Ensembl chr13:65,195,376...65,301,725

G

formyl peptide receptor 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:44,568,338...44,574,614
Ensembl chr 6:44,568,501...44,569,559

G

FRAS1 related extracellular matrix 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:17,121,063...17,310,149
Ensembl chr 3:17,129,126...17,300,363

G

gamma-aminobutyric acid type A receptor subunit beta2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:25741868 PMID:28492532

NCBI chr23:63,636,094...63,894,587
Ensembl chr23:63,637,109...63,893,370

G

gamma-aminobutyric acid type A receptor subunit gamma1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr27:4,133,320...4,224,366
Ensembl chr27:4,133,161...4,219,122

G

glyceraldehyde-3-phosphate dehydrogenase, spermatogenic

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:30,458,076...30,470,139
Ensembl chr 6:30,458,383...30,470,139

G

growth differentiation factor 10

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:44,066,979...44,080,319
Ensembl chr 9:44,067,469...44,079,522

G

GEN1 Holliday junction 5' flap endonuclease

ISO

ClinVar Annotator: match by term: GEN1-related condition | ClinVar Annotator: match by term: GEN1-related prostate cancer

PMID:25741868 PMID:28492532

NCBI chr14:89,886,102...89,917,485
Ensembl chr14:89,888,853...89,911,293

G

guided entry of tail-anchored proteins factor 3, ATPase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:11,426,857...11,437,343
Ensembl chr 6:11,426,787...11,437,119

G

GDNF family receptor alpha 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr23:40,927,283...40,948,591
Ensembl chr23:40,927,289...40,946,023

G

GLI family zinc finger 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:53,371,929...53,384,339
Ensembl chr11:53,375,558...53,385,269

G

G protein subunit gamma transducin 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

G

glyceronephosphate O-acyltransferase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:68,518,643...68,553,055
Ensembl chr25:68,518,300...68,553,767

G

golgi membrane protein 1

ISO

protein,mRNA:increased expression:prostate

NCBI chr12:96,706,865...96,778,687
Ensembl chr12:96,708,548...96,779,065

G

gephyrin

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:43,702,384...44,421,890
Ensembl chr24:43,880,344...44,422,276

G

G protein-coupled receptor 26

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:116,329,336...116,353,073
Ensembl chr 9:116,329,419...116,351,784

G

G protein-coupled receptor 55

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:116,945,216...116,967,559
Ensembl chr10:116,947,905...116,948,864

G

G protein-coupled receptor 82

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:38,918,871...38,932,011
Ensembl chr X:38,930,844...38,931,854

G

growth factor receptor bound protein 2

treatment
disease_progression

ISO

DNA:amplification, mutation

PMID:17372910 PMID:28930697

RGD:13504750 RGD:13504751

NCBI chr16:46,264,818...46,346,426
Ensembl chr16:46,264,825...46,347,156

G

glutamate ionotropic receptor delta type subunit 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:45,485,219...46,265,186

G

glutamate ionotropic receptor NMDA type subunit 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231

G

glutamate metabotropic receptor 8

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr21:95,264,905...96,060,822
Ensembl chr21:95,264,765...96,050,554

G

gastrin releasing peptide

ISO

protein:increased expression:serum (human)

NCBI chr18:20,496,201...20,508,551
Ensembl chr18:20,496,516...20,507,153

G

glutamate rich WD repeat containing 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:41,707,669...41,715,293
Ensembl chr 6:41,707,743...41,714,425

G

glutathione S-transferase mu 1

ISO

NCBI chr20:23,854,969...23,861,634

G

glutathione S-transferase pi 1

susceptibility

ISO

DNA:polymorphism:exon:p.I105V (human)

PMID:9111193 PMID:17067754

RGD:4142515 RGD:6906883

NCBI chr 1:6,676,897...6,679,936

G

heme binding protein 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:34,985,834...34,995,037
Ensembl chr13:34,986,129...34,994,809

G

HEPACAM family member 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr21:55,788,028...55,829,876
Ensembl chr21:55,788,084...55,824,890

G

HHIP like 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:77,602,306...77,633,281
Ensembl chr24:77,602,532...77,632,232

G

hypoxia inducible factor 1 subunit alpha

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:38,873,830...38,927,657
Ensembl chr24:38,873,861...38,928,288

G

homeodomain interacting protein kinase 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:34,834,526...34,848,751
Ensembl chr 6:34,835,059...34,848,138

G

histone cell cycle regulator

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:6,324,050...6,424,999
Ensembl chr19:6,324,253...6,425,641

G

HLF transcription factor, PAR bZIP family member

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:38,048,114...38,108,798
Ensembl chr16:38,048,097...38,108,725

G

hemicentin 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:43,230,265...43,677,315
Ensembl chr25:43,231,328...43,554,097

G

heterogeneous nuclear ribonucleoprotein K

ISO

protein:increased expression:prostate gland (human)

NCBI chr12:94,768,403...94,789,957
Ensembl chr12:94,768,480...94,789,743

G

homeobox B13

ISO

ClinVar Annotator: match by term: PROSTATE CANCER, SUSCEPTIBILITY TO

PMID:8756292 PMID:15964834 PMID:17138648 PMID:22236224 PMID:22714738 More...

NCBI chr16:69,137,561...69,141,615
Ensembl chr16:69,137,585...69,139,382

G

HPS3 biogenesis of lysosomal organelles complex 2 subunit 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:41,537,122...41,581,994
Ensembl chr15:41,537,837...41,581,929

G

5-hydroxytryptamine receptor 2C

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:102,190,355...102,499,928
Ensembl chr X:102,325,731...102,497,278

G

5-hydroxytryptamine receptor 5A

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr21:123,229,239...123,244,360
Ensembl chr21:123,229,816...123,241,481

G

HtrA serine peptidase 2

ISO

mRNA, protein:increased expression:prostate (human)

NCBI chr14:32,745,436...32,749,176
Ensembl chr14:32,743,708...32,748,577

G

inhibitor of Bruton tyrosine kinase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:6,836,527...6,915,731
Ensembl chr13:6,834,532...6,915,778

G

intercellular adhesion molecule 1

ISO

NCBI chr 6:9,320,991...9,338,125
Ensembl chr 6:9,322,550...9,338,263

G

interferon induced with helicase C domain 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:47,676,799...47,732,310
Ensembl chr10:47,676,920...47,732,264

G

intraflagellar transport 43

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:53,231,293...53,329,116
Ensembl chr24:53,231,300...53,329,109

G

insulin like growth factor 1 receptor

disease_progression

ISO

NCBI chr29:17,212,206...17,534,036
Ensembl chr29:17,459,404...17,526,930

G

insulin like growth factor 2 receptor

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:87,587,717...87,723,795
Ensembl chr13:87,587,907...87,724,116

G

insulin like growth factor binding protein 3

severity
no_association

ISO

DNA:SNP:promoter:rs2854744, homozygous C allele associated with 2x increased risk
DNA:SNP:promoter:rs2854744 C allele associated with low grade tumors only, odds ratio=4.1 for low grade vs 1.0 for high grade
DNA:SNP:promoter:no association with rs2854744, 440 cases and 480 related controls from Cleveland, OH and Detroit, MI

PMID:15006930 PMID:17668637 PMID:17724372

RGD:2290008 RGD:2290012 RGD:2290015

NCBI chr21:12,905,309...12,914,199
Ensembl chr21:12,905,280...12,914,205

G

inhibitor of nuclear factor kappa B kinase subunit beta

ISO

protein:increased serine phosphorylation:prostate gland

NCBI chr 8:40,267,532...40,325,282
Ensembl chr 8:40,268,079...40,326,381

G

interleukin 16

ISO

DNA:SNP:exon:rs4072111 (human)

NCBI chr26:2,080,985...2,208,764
Ensembl chr26:2,077,228...2,208,431

G

interleukin 33

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:73,235,585...73,283,665
Ensembl chr12:73,237,406...73,252,436

G

integrin linked kinase

disease_progression

ISO

mRNA:decreased expression:tumor:lower in high versus low Gleason score tumors (p<0.05 compared to at least one housekeeping gene)
protein:decreased expression:tumor:significantly lower in benign prostatic hyperplasia then any prostate cancer (p<0.01), gradient of expression from BPH to poorly differentiated C+D stage neoplasms

PMID:15704679 PMID:18336616

RGD:2301729 RGD:2301731

NCBI chr 1:58,214,630...58,221,770
Ensembl chr 1:58,213,310...58,221,217

G

interphotoreceptor matrix proteoglycan 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:25741868

NCBI chr22:79,560,987...79,664,906
Ensembl chr22:79,561,498...79,660,472

G

inhibitor of growth family member 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:6,683,994...6,696,888
Ensembl chr11:6,684,897...6,696,852

G

inhibin subunit alpha

ISO

mRNA,protein:decreased expression:malignant tumors

NCBI chr10:105,467,575...105,471,388
Ensembl chr10:105,467,963...105,471,688

G

indolethylamine N-methyltransferase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr21:27,635,727...27,707,463
Ensembl chr21:27,634,903...27,639,800

G

insulin

disease_progression

ISO

NCBI chr 1:1,965,128...1,969,090

G

integrator complex subunit 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:10,037,176...10,085,499

G

integrator complex subunit 8

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:89,790,758...89,846,764
Ensembl chr 8:89,790,758...89,850,755

G

immunity related GTPase Q

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:37,111,782...37,116,258
Ensembl chr 6:37,112,015...37,115,322

G

integrin subunit alpha D

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:28,095,341...28,128,498

G

integrin subunit beta 6

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:45,506,355...45,650,979
Ensembl chr10:45,504,987...45,595,543

G

inter-alpha-trypsin inhibitor heavy chain 5

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:7,621,779...7,723,731
Ensembl chr 9:7,617,999...7,723,662

G

ITPRIP like 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:745,194...748,203
Ensembl chr14:745,331...750,727

G

Janus kinase 1

severity

ISO

DNA:frameshift mutations

NCBI chr20:68,122,134...68,253,361
Ensembl chr20:68,122,173...68,252,042

G

junction plakoglobin

severity

ISO

DNA,mRNA,protein:loss of heterozygosity, decreased expression:tumor:relative to either BPH or normal prostate
protein:increased expression:tumor:significantly associated with capsular invasion (p=0.007 for all cases, p=0.015 for cases with Gleason score 5-7)

PMID:10206308 PMID:15781623

RGD:2291864 RGD:2291876

NCBI chr16:64,470,974...64,503,085
Ensembl chr16:64,470,959...64,503,322

G

lysine acetyltransferase 7

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:43,508,888...43,548,411
Ensembl chr16:43,510,483...43,548,517

G

katanin catalytic subunit A1 like 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr18:33,848,471...33,967,832
Ensembl chr18:33,848,748...33,907,092

G

potassium voltage-gated channel modifier subfamily F member 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:96,695,647...96,698,931
Ensembl chr14:96,695,961...96,697,445

G

potassium inwardly rectifying channel subfamily J member 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:119,971,282...120,040,752
Ensembl chr 1:119,969,370...119,986,411

G

potassium inwardly rectifying channel subfamily J member 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:21,085,857...21,114,961
Ensembl chr19:21,086,322...21,087,659

G

potassium calcium-activated channel subfamily N member 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:8,961,833...9,124,728
Ensembl chr20:8,962,302...9,124,166

G

potassium voltage-gated channel subfamily Q member 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:126,566,288...126,921,354
Ensembl chr 8:126,566,545...126,622,712

G

potassium voltage-gated channel subfamily Q member 5

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr17:1,932,962...2,495,926
Ensembl chr17:1,930,803...2,128,570

G

lysine demethylase 3A

ISO

mRNA:increased expression:prostate gland (human)
mRNA:increased expression:prostate (human)

PMID:20127736 PMID:22120715

RGD:9586733 RGD:9587486

NCBI chr14:20,668,215...20,721,854
Ensembl chr14:20,668,821...20,720,759

G

lysine demethylase 4A

ISO

mRNA:increased expression:prostate (human)

NCBI chr20:89,108,090...89,164,657
Ensembl chr20:89,073,876...89,164,663

G

lysine demethylase 4B

ISO

mRNA:increased expression:prostate (human)

NCBI chr 6:4,649,140...4,831,634
Ensembl chr 6:4,649,221...4,831,636

G

lysine demethylase 4C

severity

ISO

mRNA:increased expression:prostate gland (human)

NCBI chr12:72,346,194...72,763,040
Ensembl chr12:72,347,071...72,761,666

G

lysine demethylase 5A

ISO

mRNA:decreased expression:prostate gland (human)

NCBI chr11:285,206...381,481
Ensembl chr11:286,728...381,430

G

lysine demethylase 5B

severity

ISO

mRNA:increased expression:prostate gland (human)

NCBI chr25:26,599,740...26,685,256
Ensembl chr25:26,600,736...26,683,632

G

lysine demethylase 6A

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:42,053,272...42,291,013
Ensembl chr X:42,053,336...42,290,526

G

kinase insert domain receptor

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:13,435,059...13,482,236
Ensembl chr 7:13,435,096...13,482,771

G

KIAA1755 ortholog

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:25,490,719...25,540,750
Ensembl chr 2:25,504,610...25,540,756

G

kinesin family member 12

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:25,486,907...25,495,445
Ensembl chr12:25,487,832...25,495,557

G

kinesin family member 16B

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:45,189,908...45,495,837
Ensembl chr 2:45,189,756...45,495,725

G

kinesin family member 5A

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr11:53,458,795...53,493,801

G

KLF transcription factor 6

ISO

NCBI chr 9:3,872,376...3,881,238
Ensembl chr 9:3,875,356...3,881,229

G

kelch like family member 20

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:55,407,648...55,473,195
Ensembl chr25:55,405,713...55,473,175

G

kallikrein related peptidase 10

susceptibility

ISO

DNA:SNP:exon:p.A50S (human)

NCBI chr 6:44,034,371...44,039,966
Ensembl chr 6:44,034,682...44,038,607

G

kallikrein related peptidase 13

ISO

protein:decreased expression:prostate

NCBI chr 6:44,069,309...44,085,681
Ensembl chr 6:44,069,324...44,083,884

G

kallikrein related peptidase 4

ISO

protein:increased expression:prostate gland

PMID:12370833 PMID:17545602

RGD:2314854 RGD:2314857

NCBI chr 6:43,921,920...43,935,224
Ensembl chr 6:43,922,052...43,934,253

G

kallikrein related peptidase 6

ISO

protein:decreased expression:prostate

NCBI chr 6:43,980,680...43,991,873
Ensembl chr 6:43,980,701...43,990,060

G

killin, p53 regulated DNA replication inhibitor

ISO

ClinVar Annotator: match by term: Prostate cancer

PMID:25741868 PMID:26467025 PMID:27535533

NCBI chr 9:81,304,883...81,307,162

G

lysine methyltransferase 2A

ISO

mRNA:decreased expression:prostate gland (human)

NCBI chr 1:109,819,748...109,912,763
Ensembl chr 1:109,853,758...109,908,113

G

lysine methyltransferase 2B

ISO

mRNA:decreased expression:prostate gland (human)

NCBI chr 6:30,626,723...30,648,204
Ensembl chr 6:30,626,848...30,647,883

G

lysine methyltransferase 2C

ISO

mRNA:decreased expression:prostate gland (human)

NCBI chr21:120,299,295...120,587,843
Ensembl chr21:120,301,188...120,587,137

G

lysine methyltransferase 2D

ISO

mRNA:decreased expression:prostate gland (human)

NCBI chr11:45,260,873...45,303,898
Ensembl chr11:45,263,408...45,302,423

G

lysine methyltransferase 2E (inactive)

ISO

mRNA:decreased expression:prostate gland (human)

NCBI chr21:73,930,957...74,030,434
Ensembl chr21:73,930,932...74,029,673

G

lysine methyltransferase 5A

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:118,712,964...118,743,322
Ensembl chr11:118,723,029...118,743,325

G

kinetochore associated 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:117,866,814...117,966,297
Ensembl chr11:117,869,711...117,963,907

G

keratinocyte proline rich protein

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:10,955,183...10,959,767
Ensembl chr20:10,955,971...10,957,707

G

KRAS proto-oncogene, GTPase

ISO

OMIM:176807 | OMIM:300147 | OMIM:300704 | OMIM:601518 | OMIM:602759 | OMIM:608656 | OMIM:608658 | OMIM:609299 | OMIM:609558 | OMIM:610321 | OMIM:610997 | OMIM:611100 | OMIM:611868 | OMIM:611928 | OMIM:611955 | OMIM:611958 | OMIM:611959

NCBI chr11:24,963,396...25,010,747
Ensembl chr11:24,973,619...25,005,191

G

keratin 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:48,810,671...48,817,436
Ensembl chr11:48,810,677...48,816,363

G

keratin 9

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:64,669,805...64,677,091
Ensembl chr16:64,670,844...64,677,001

G

laminin subunit alpha 5

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:1,872,740...1,930,037
Ensembl chr 2:1,872,832...1,929,854

G

La ribonucleoprotein 1B

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:75,189,782...75,343,852
Ensembl chr 7:75,204,960...75,342,059

G

ligand dependent nuclear receptor corepressor

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:90,009,449...90,157,340
Ensembl chr 9:90,152,909...90,156,646

G

lymphoid enhancer binding factor 1

ISO

associated with prostate cancer

NCBI chr 7:55,974,770...56,096,214
Ensembl chr 7:55,990,621...56,094,110

G

DNA ligase 4

treatment

ISO

NCBI chr 3:86,576,200...86,587,097
Ensembl chr 3:86,577,304...86,580,039

G

lectin, mannose binding 1 like

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr26:8,645,361...8,659,139
Ensembl chr26:8,646,256...8,658,576

G

leishmanolysin like peptidase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:91,676,060...91,745,251
Ensembl chr15:91,676,379...91,744,928

G

arylamine N-acetyltransferase 1

susceptibility

ISO

DNA:polymorphism

NCBI chr 8:16,302,296...16,315,406
Ensembl chr 8:16,314,446...16,315,318

G

arylamine N-acetyltransferase 2

susceptibility

ISO

DNA:polymorphism

NCBI chr 8:16,451,144...16,494,961
Ensembl chr 8:16,493,749...16,494,621

G

C2 calcium dependent domain containing 6

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:87,133,453...87,303,521
Ensembl chr10:87,133,461...87,302,735

G

taste receptor type 2 member 20

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:10,935,490...10,938,807
Ensembl chr11:10,936,104...10,937,030

G

AGBL carboxypeptidase 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:82,893,087...84,293,578
Ensembl chr20:84,054,586...84,104,279

G

uncharacterized LOC103234261

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:19,712,698...19,755,896

G

uncharacterized LOC103235170

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:45,201,650...45,208,617

G

olfactory receptor 1S2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:15,053,977...15,055,511

G

pantetheine hydrolase VNN2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:40,756,307...40,776,538
Ensembl chr13:40,762,296...40,776,872

G

serotransferrin

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:56,586,311...56,618,304
Ensembl chr15:56,586,104...56,618,149

G

myosin-8

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:9,733,585...9,765,740
Ensembl chr16:9,733,717...9,763,255

G

myosin-3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:25741868 PMID:28492532 PMID:31030430

NCBI chr16:9,966,801...9,999,458
Ensembl chr16:9,966,922...9,994,402

G

beta-glucuronidase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr28:1,679,682...1,699,238

G

zinc finger protein 773

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

G

E3 ubiquitin-protein ligase TRIM34

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:61,104,681...61,123,901

G

caspase-1

ISO

protein:decreased expression:prostate gland

NCBI chr 1:96,389,697...96,400,610
Ensembl chr 1:96,389,657...96,400,849

G

lon peptidase 2, peroxisomal

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:34,050,284...34,160,363
Ensembl chr 5:34,050,446...34,160,165

G

LDL receptor related protein 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:53,039,147...53,125,041
Ensembl chr11:53,039,364...53,125,776

G

LDL receptor related protein 1B

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:25,611,400...27,511,903
Ensembl chr10:25,616,590...26,609,111

G

LDL receptor related protein 6

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:12,016,542...12,170,496
Ensembl chr11:12,021,560...12,170,663

G

LDL receptor related protein associated protein 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr27:45,206,455...45,225,766
Ensembl chr27:45,206,618...45,225,767

G

leucine rich repeat containing 37 member A3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

G

microtubule actin crosslinking factor 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:93,413,111...93,814,388

G

mitotic arrest deficient 1 like 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:11423979 PMID:25741868

NCBI chr28:19,358,942...19,768,079
Ensembl chr28:19,359,233...19,768,078

G

membrane associated guanylate kinase, WW and PDZ domain containing 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr21:69,460,345...70,916,684

G

MAM domain containing 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:81,104,453...81,285,287
Ensembl chr12:81,105,126...81,285,531

G

mastermind like transcriptional coactivator 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr23:81,456,537...81,508,893
Ensembl chr23:81,496,033...81,506,497

G

mastermind like domain containing 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:124,955,942...125,093,874
Ensembl chr X:125,025,375...125,083,319

G

mitogen-activated protein kinase kinase 5

ISO

protein:increased expression

NCBI chr26:15,694,760...15,956,814
Ensembl chr26:15,693,811...15,956,918

G

mitogen-activated protein kinase kinase 7

ISO

mRNA:splice variant:exon 2: (human)

NCBI chr 6:7,355,387...7,365,944
Ensembl chr 6:7,355,434...7,364,398

G

mitogen-activated protein kinase kinase kinase 7

ISO

DNA:deletion

NCBI chr13:15,284,927...15,360,539
Ensembl chr13:15,284,923...15,360,832

G

mitogen-activated protein kinase 10

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:34,394,600...34,725,658
Ensembl chr 7:34,399,544...34,564,212

G

mitogen-activated protein kinase 7

ISO

NCBI chr16:17,962,827...17,969,027
Ensembl chr16:17,964,408...17,968,714

G

microtubule associated protein tau

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:59,894,400...60,020,723
Ensembl chr16:59,890,221...59,955,612

G

MCC regulator of WNT signaling pathway

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr23:16,309,574...16,773,736
Ensembl chr23:16,310,968...16,579,343

G

magnesium dependent phosphatase 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:1,197,088...1,199,725
Ensembl chr24:1,197,168...1,199,169

G

mediator complex subunit 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:66,719,393...66,764,902
Ensembl chr16:66,719,423...66,762,896

G

matrix metallopeptidase 13

disease_progression

ISO

protein:increased expression:plasma:higher concentration in patients with metastases vs non-metastatic PCa, BPH or control patients

NCBI chr 1:94,322,473...94,370,665
Ensembl chr 1:94,322,979...94,334,747

G

matrix metallopeptidase 15

disease_progression

ISO

NCBI chr 5:43,961,288...43,982,182
Ensembl chr 5:43,960,891...43,982,261

G

matrix metallopeptidase 2

disease_progression

ISO

protein:increased expression:prostate gland

NCBI chr 5:41,264,382...41,291,657
Ensembl chr 5:41,264,354...41,291,004

G

matrix metallopeptidase 7

ISO

NCBI chr 1:93,889,189...93,901,077
Ensembl chr 1:93,889,198...93,899,587

G

mitochondrial ribosomal protein L46

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr29:7,025,380...7,033,219
Ensembl chr29:7,025,442...7,033,219

G

mutS homolog 2

disease_progression

ISO

NCBI chr14:59,730,101...59,802,857
Ensembl chr14:59,729,789...59,802,819

G

mutS homolog 6

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:25741868 PMID:28492532

NCBI chr14:59,375,602...59,400,252
Ensembl chr14:59,375,691...59,400,174

G

microseminoprotein beta

ISO

OMIM:176807 | OMIM:300147 | OMIM:300704 | OMIM:601518 | OMIM:602759 | OMIM:608656 | OMIM:608658 | OMIM:609299 | OMIM:609558 | OMIM:610321 | OMIM:610997 | OMIM:611100 | OMIM:611868 | OMIM:611928 | OMIM:611955 | OMIM:611958 | OMIM:611959

NCBI chr 9:41,796,948...41,810,373
Ensembl chr 9:41,803,922...41,810,276

G

macrophage scavenger receptor 1

susceptibility

ISO

DNA:SNPs
ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:12244320 PMID:12958598 PMID:17903305 PMID:21791690 PMID:24082139 More...

NCBI chr 8:14,221,389...14,305,059
Ensembl chr 8:14,220,529...14,304,946

G

MDM2 binding protein

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:115,023,272...115,109,948
Ensembl chr 8:115,029,029...115,102,088

G

methylenetetrahydrofolate reductase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:119,987,667...120,003,611
Ensembl chr20:119,990,133...120,002,950

G

mitochondrial nucleoid associated protein 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:48,388,665...48,404,425
Ensembl chr16:48,386,342...48,403,958

G

mechanistic target of rapamycin kinase

treatment

ISO

NCBI chr20:120,522,667...120,678,988
Ensembl chr20:120,525,737...120,679,020

G

mucin 1, cell surface associated

severity

ISO

NCBI chr20:8,641,701...8,646,739
Ensembl chr20:8,642,842...8,646,962

G

mucin 17, cell surface associated

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr28:12,138,287...12,142,284

G

mucin 6, oligomeric mucus/gel-forming

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

G

MX dynamin like GTPase 1

susceptibility

ISO

DNA:SNP:promoter:-g.88G>T (rs2071430) (human)

NCBI chr 2:85,333,327...85,368,179
Ensembl chr 2:85,338,530...85,368,507

G

MAX interactor 1, dimerization protein

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:103,131,534...103,211,609
Ensembl chr 9:103,131,420...103,209,231

G

matrix remodeling associated 5

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:1,525,422...1,563,711

G

MYC proto-oncogene, bHLH transcription factor

susceptibility
severity

ISO

DNA:snp:intron:IVS1-355T>A rs3891248 (human)
protein:increased expression:prostate gland (human)

PMID:18483343 PMID:20140016

RGD:7207432 RGD:7240541

NCBI chr 8:122,282,989...122,288,392
Ensembl chr 8:122,282,630...122,288,384

G

MYC binding protein 2

disease_progression

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:26408707

NCBI chr 3:56,128,691...56,412,854
Ensembl chr 3:56,128,428...56,412,923

G

myosin light chain kinase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr22:57,032,264...57,259,253
Ensembl chr22:57,065,331...57,257,464

G

myosin XVI

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:86,850,362...87,550,840

G

myosin XVIIIA

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:22,836,856...22,942,366

G

myosin IA

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:52,939,744...52,961,957
Ensembl chr11:52,936,090...52,961,486

G

myosin VI

ISO

protein:increased expression:prostate gland epithelium, perinuclear region of cytoplasm

NCBI chr13:527,361...620,418
Ensembl chr13:457,495...618,858

G

myocardin

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:11,923,464...12,100,897
Ensembl chr16:12,000,197...12,095,552

G

myotilin

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr23:40,542,153...40,567,873
Ensembl chr23:40,548,100...40,568,217

G

myelin regulatory factor

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:12,066,277...12,103,091

G

NSF attachment protein beta

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:52,379,633...52,395,274

G

nibrin

susceptibility

ISO

DNA:deletion, loss of heterozygosity
ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: Prostate cancer

PMID:14973119 PMID:23265383 PMID:23555315 PMID:25741868 PMID:26467025 More...

NCBI chr 8:85,017,807...85,069,219
Ensembl chr 8:85,015,752...85,069,028

G

nuclear receptor coactivator 1

disease_progression

ISO

NCBI chr14:82,898,368...83,028,137
Ensembl chr14:82,897,348...83,013,589

G

nuclear receptor coactivator 2

ISO

mRNA:increased expression:prostate (human)

NCBI chr 8:65,855,232...66,151,733
Ensembl chr 8:65,855,235...66,040,947

G

nuclear receptor coactivator 3

ISO

mRNA:increased expression:prostate (human)

NCBI chr 2:16,270,218...16,423,381
Ensembl chr 2:16,273,717...16,423,318

G

nuclear receptor coactivator 4

severity

ISO

protein:increased expression:prostate gland
mRNA:decreased expression:prostate gland

PMID:12368219 PMID:15166229

RGD:2293534 RGD:2293535

NCBI chr 9:41,813,018...41,836,974
Ensembl chr 9:41,826,320...41,837,505

G

NECAP endocytosis associated 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:115,865,118...115,882,157
Ensembl chr20:115,864,746...115,882,392

G

NIMA related kinase 9

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:52,297,211...52,342,359
Ensembl chr24:52,296,261...52,342,724

G

negative elongation factor complex member C/D

disease_progression

ISO

NCBI chr 2:5,146,137...5,159,965
Ensembl chr 2:5,146,575...5,159,883

G

neural EGFL like 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:43,416,052...44,335,894
Ensembl chr 1:43,415,553...44,335,381

G

neuropilin and tolloid like 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:32,929,091...32,991,240
Ensembl chr 5:32,930,692...32,979,561

G

nuclear factor kappa B subunit 1

susceptibility
treatment

ISO

DNA:SNPs, haplotype: :multiple
DNA:indel:promoter

PMID:26068031 PMID:26788504 PMID:28797847

RGD:11054182 RGD:11554936 RGD:13506729

NCBI chr 7:50,589,494...50,711,472
Ensembl chr 7:50,589,856...50,711,498

G

NFKB inhibitor alpha

disease_progression
susceptibility
no_association

ISO

protein:increased serine phosphorylation
ClinVar Annotator: match by term: Malignant tumor of prostate
DNA:SNPs:promoter:-826C>T, -881A>G (human)
DNA:SNPs: :rs2233406, rs3138053 (human)
DNA:polymorphism:3' UTR

PMID:23093296 PMID:26068031 PMID:26834482

RGD:11054182 RGD:13506766 RGD:13506767

NCBI chr24:12,211,619...12,216,185
Ensembl chr24:12,210,281...12,214,854

G

NHS actin remodeling regulator

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:15,803,386...16,183,809
Ensembl chr X:16,168,609...16,183,787

G

sodium/potassium transporting ATPase interacting 2

ISO

mRNA, protein:decreased expression:prostate

NCBI chr13:48,876,514...50,121,382

G

NK3 homeobox 1

ISO

OMIM:176807 | OMIM:300147 | OMIM:300704 | OMIM:601518 | OMIM:602759 | OMIM:608656 | OMIM:608658 | OMIM:609299 | OMIM:609558 | OMIM:610321 | OMIM:610997 | OMIM:611100 | OMIM:611868 | OMIM:611928 | OMIM:611955 | OMIM:611958 | OMIM:611959

NCBI chr 8:21,792,069...21,797,258
Ensembl chr 8:21,791,422...21,796,319

G

NLR family pyrin domain containing 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr16:4,930,643...4,983,378

G

NLR family pyrin domain containing 7

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:19066229 PMID:21507883 PMID:24105752

NCBI chr 6:47,534,730...47,560,380
Ensembl chr 6:47,539,594...47,552,265

G

NMD3 ribosome export adaptor

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:29,592,847...29,765,928
Ensembl chr15:29,592,577...29,621,567

G

nitric oxide synthase 3

disease_progression

ISO

DNA:polymorphism:exon:p.E298D (human)

NCBI chr21:119,174,829...119,196,840

G

notch receptor 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:7732783 PMID:15364702 PMID:16328531 PMID:23265383 PMID:25033846 More...

NCBI chr 6:13,762,570...13,803,676
Ensembl chr 6:13,761,512...13,793,359

G

nuclear receptor subfamily 3 group C member 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr23:45,904,926...46,031,804
Ensembl chr23:45,904,873...46,031,125

G

NRAS proto-oncogene, GTPase

disease_progression

ISO

NCBI chr20:18,953,273...18,966,002
Ensembl chr20:18,953,883...18,961,931

G

netrin 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:91,052,142...91,172,463
Ensembl chr11:91,051,662...91,172,522

G

NACHT and WD repeat domain containing 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:15,255,116...15,318,589
Ensembl chr 6:15,221,120...15,318,470

G

8-oxoguanine DNA glycosylase

susceptibility

ISO

DNA:missense mutation:exon:p.S326C (1245C>G) (rs1052133) (human)
DNA:missense mutation:cds:p.S326C (human)

PMID:19914098 PMID:24649009

RGD:8657136 RGD:8657378

NCBI chr22:45,757,414...45,763,690

G

oncoprotein induced transcript 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:58,338,703...58,378,492
Ensembl chr 9:58,337,958...58,377,734

G

Obg like ATPase 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:59,589,475...59,766,259

G

olfactomedin like 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:19,676,162...19,679,013
Ensembl chr20:19,676,132...19,679,124

G

olfactory receptor family 2 subfamily T member 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

G

olfactory receptor family 6 subfamily K member 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:5,221,383...5,224,559

G

olfactory receptor family 8 subfamily K member 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:16,611,009...16,613,628
Ensembl chr 1:16,612,440...16,613,372

G

OXA1L mitochondrial inner membrane insertase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr29:23,131,273...23,137,470
Ensembl chr29:23,131,453...23,137,245

G

p21 (RAC1) activated kinase 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:33,715,695...33,769,272
Ensembl chr 6:33,759,462...33,770,497

G

PALM2 and AKAP2 fusion

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:29,371,705...29,908,100
Ensembl chr12:29,371,209...29,604,909

G

par-3 family cell polarity regulator

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:33,396,738...34,104,479
Ensembl chr 9:33,396,246...33,803,997

G

protocadherin beta 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr23:43,680,654...43,734,646

G

pecanex 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:48,113,578...48,314,005
Ensembl chr24:48,113,348...48,312,922

G

phosphodiesterase 1C

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr21:26,094,604...26,712,127
Ensembl chr21:26,501,264...26,598,053

G

phosphodiesterase 3A

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:20,235,814...20,545,740
Ensembl chr11:20,236,430...20,540,900

G

phosphodiesterase 6B

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr27:48,117,495...48,168,727
Ensembl chr27:48,118,190...48,162,368

G

phosphodiesterase 7B

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:37,230,419...37,560,391
Ensembl chr13:37,226,606...37,378,218

G

platelet derived growth factor receptor beta

ISO

NCBI chr23:52,724,061...52,766,264
Ensembl chr23:52,724,005...52,766,234

G

pyruvate dehydrogenase kinase 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr21:53,445,607...53,458,729
Ensembl chr21:53,445,457...53,460,776

G

pyruvate dehydrogenase phosphatase catalytic subunit 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:52,575,280...52,583,614
Ensembl chr 5:52,580,423...52,582,009

G

3-phosphoinositide dependent protein kinase 1

treatment

ISO

G

phosphatidylethanolamine binding protein 1

ISO

NCBI chr11:113,469,845...113,479,177

G

pyroglutamyl-peptidase I

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:16,818,743...16,837,565
Ensembl chr 6:16,818,643...16,836,949

G

PHD finger protein 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:103,959,502...104,055,711
Ensembl chr12:104,007,498...104,055,711

G

PHD finger protein 8

ISO

mRNA:increased expression:prostate (human)

NCBI chr X:50,058,687...50,172,827
Ensembl chr X:50,058,273...50,172,086

G

PH domain and leucine rich repeat protein phosphatase 1

disease_progression

ISO

mRNA:decreased expression:tumor:lower in high versus low Gleason score tumors (p<0.05 compared to at least one housekeeping gene)

NCBI chr18:16,786,128...17,051,250

G

phosphatidylinositol glycan anchor biosynthesis class H

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:44,790,528...44,848,870
Ensembl chr24:44,838,242...44,848,598

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

ISO

ClinVar Annotator: match by term: Prostate cancer

PMID:15520168 PMID:25741868

NCBI chr15:10,218,034...10,304,874
Ensembl chr15:10,218,805...10,294,316

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

disease_progression
treatment

ISO

PMID:18372911 PMID:20103642

RGD:13506809 RGD:13506810

NCBI chr15:51,705,585...51,885,848
Ensembl chr15:51,775,733...51,889,238

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr21:75,781,812...75,823,404
Ensembl chr21:75,784,648...75,825,496

G

phosphoinositide-3-kinase regulatory subunit 1

disease_progression

ISO

mRNA:decreased expression:tumor:lower in high versus low Gleason score tumors (p<0.05 compared to at least one housekeeping gene)
ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:18336616 PMID:23265383

NCBI chr 4:64,321,296...64,406,188
Ensembl chr 4:64,321,078...64,406,519

G

phosphoinositide-3-kinase regulatory subunit 2

ISO

NCBI chr 6:16,620,673...16,637,511
Ensembl chr 6:16,621,606...16,636,937

G

paired like homeodomain 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:58,501,669...58,526,413
Ensembl chr 7:58,501,559...58,507,318

G

polycystin 2 like 1, transient receptor potential cation channel

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:93,319,408...93,363,389

G

PKHD1 ciliary IPT domain containing fibrocystin/polyductin

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr17:20,411,746...20,873,601

G

plasminogen activator, urokinase

severity

ISO

protein:increased expression:serum (human)

NCBI chr 9:57,452,904...57,459,345
Ensembl chr 9:57,452,761...57,459,286

G

phospholipase B1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:78,960,601...79,122,082
Ensembl chr14:78,960,202...79,096,555

G

phospholipase C beta 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:28,650,604...29,059,435
Ensembl chr 2:28,650,421...28,915,290

G

pleckstrin homology domain containing A4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:42,076,695...42,110,904

G

pleckstrin homology and RhoGEF domain containing G1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:78,034,968...78,285,288
Ensembl chr13:78,154,150...78,287,996

G

pleckstrin homology and RhoGEF domain containing G4B

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:10,284...129,774

G

prostate transmembrane protein, androgen induced 1

disease_progression

ISO

NCBI chr 2:6,403,358...6,465,958
Ensembl chr 2:6,404,515...6,465,982

G

PMS1 homolog 2, mismatch repair system component

disease_progression

ISO

NCBI chr28:15,174,359...15,209,962
Ensembl chr28:15,172,100...15,209,852

G

pancreatic lipase related protein 1

ISO

NCBI chr 9:109,397,970...109,417,422
Ensembl chr 9:109,399,227...109,417,351

G

podocan

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:79,834,491...79,858,606
Ensembl chr20:79,834,497...79,858,087

G

DNA polymerase kappa

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:25741868 PMID:26046662

NCBI chr 4:69,842,887...69,948,285
Ensembl chr 4:69,872,752...69,948,249

G

DNA polymerase nu

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr27:46,523,052...46,694,474

G

paraoxonase 1

ISO

protein:increased activity:serum (human)

NCBI chr21:53,713,434...53,739,658
Ensembl chr21:53,714,012...53,739,875

G

diphosphoinositol pentakisphosphate kinase 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr23:6,562,435...6,639,330
Ensembl chr23:6,571,657...6,641,002

G

protein phosphatase 1 regulatory subunit 3C

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:84,918,592...84,923,281
Ensembl chr 9:84,918,591...84,923,334

G

protein phosphatase 2 catalytic subunit alpha

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr23:36,999,110...37,028,916
Ensembl chr23:36,997,078...37,029,280

G

protein phosphatase 2 regulatory subunit B'gamma

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:79,703,316...79,875,379
Ensembl chr24:79,703,312...79,875,389

G

protein phosphatase 6 regulatory subunit 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:32,824,732...32,917,356
Ensembl chr19:32,866,039...32,916,534

G

PPARG related coactivator 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:95,157,759...95,183,031
Ensembl chr 9:95,157,800...95,183,037

G

phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1

ISO

protein:increased expression:prostate, lymph node

NCBI chr 2:15,152,001...15,354,556
Ensembl chr 2:15,152,096...15,354,544

G

phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:63,781,892...64,061,222
Ensembl chr 8:63,781,948...64,060,864

G

protein kinase D1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

G

peripherin 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:29,429,876...29,456,013
Ensembl chr17:29,430,545...29,453,636

G

proteasome 26S subunit, ATPase 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:67,979,449...67,995,103

G

phosphatase and tensin homolog

disease_progression

ISO

mRNA:decreased expression:tumor:lower in high versus low Gleason score tumors (p<0.05 compared to at least one housekeeping gene)
ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: Prostate cancer
DNA:deletion

RGD
ClinVar
OMIM

PMID:9259288 PMID:9399897 PMID:9467011 PMID:9856571 PMID:10232405 More...

RGD:2292502 RGD:2301729

NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146

G

prostaglandin-endoperoxide synthase 2

susceptibility

ISO

DNA:SNP:promoter:-1195G>A (human)

NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429

G

protein tyrosine kinase 2

ISO

protein:increased expression:prostate gland

NCBI chr 8:134,897,511...135,246,300

G

protein tyrosine kinase 2 beta

severity

ISO

protein:decreased expression:prostate gland

NCBI chr 8:25,437,680...25,571,594
Ensembl chr 8:25,437,564...25,571,782

G

protein tyrosine phosphatase non-receptor type 21

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:66,102,081...66,191,918
Ensembl chr24:66,101,788...66,187,987

G

protein tyrosine phosphatase non-receptor type 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:30,048,941...30,168,816
Ensembl chr12:30,083,128...30,171,473

G

protein tyrosine phosphatase receptor type D

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:70,160,253...71,237,292
Ensembl chr12:70,693,214...71,239,437

G

protein tyrosine phosphatase receptor type N2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr21:125,655,787...126,622,503

G

pyrroline-5-carboxylate reductase 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:137,823,685...137,830,630
Ensembl chr 8:137,826,293...137,830,546

G

pyrin and HIN domain family member 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:4,967,123...5,006,172
Ensembl chr20:4,967,224...5,006,035

G

RAB11 family interacting protein 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:24,851,474...24,991,482
Ensembl chr16:24,851,595...24,991,361

G

RAB33A, member RAS oncogene family

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr X:105,421,709...105,437,206
Ensembl chr X:105,424,290...105,437,169

G

Rac family small GTPase 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:19,930,799...19,949,381
Ensembl chr19:19,929,892...19,949,376

G

RAD50 double strand break repair protein

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:26467025 PMID:28492532 PMID:33339169

NCBI chr23:35,375,206...35,458,801
Ensembl chr23:35,375,305...35,458,622

G

Raf-1 proto-oncogene, serine/threonine kinase

disease_progression

ISO

NCBI chr22:48,560,270...48,643,537
Ensembl chr22:48,561,161...48,618,020

G

Rap guanine nucleotide exchange factor like 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:65,978,561...65,995,738

G

Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:89,191,220...89,294,746
Ensembl chr10:89,192,772...89,250,757

G

RAS protein activator like 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:50,838,985...51,211,683
Ensembl chr25:50,840,184...50,941,942

G

Ras association domain family member 1

disease_progression

ISO

DNA:hypermethylation:promoter

NCBI chr22:11,716,969...11,728,646
Ensembl chr22:11,716,918...11,725,027

G

RB transcriptional corepressor 1

ISO

DNA:loss of heterozygosity

NCBI chr 3:26,220,783...26,393,671
Ensembl chr 3:26,220,803...26,394,546

G

RB associated KRAB zinc finger

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr28:16,594,449...16,648,577

G

regulator of chromosome condensation 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:115,139,279...115,171,872

G

RERG like

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:17,928,575...17,938,408
Ensembl chr11:17,928,557...17,938,351

G

Rho related BTB domain containing 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:21,069,255...21,098,000
Ensembl chr 8:21,079,411...21,097,026

G

RIPOR family member 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:13,282,704...13,384,297
Ensembl chr 2:13,339,843...13,383,203

G

ring finger protein, LIM domain interacting

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:64,178,159...64,205,759

G

ribonuclease L

ISO

ClinVar Annotator: match by term: Prostate cancer

PMID:11799394 PMID:25741868 PMID:28492532

NCBI chr25:46,779,221...46,795,854
Ensembl chr25:46,779,700...46,795,842

G

ribosomal protein L10 like

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:23,667,440...23,669,041
Ensembl chr24:23,668,304...23,668,948

G

ribosomal protein S6 kinase C1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:16,298,782...16,510,108
Ensembl chr25:16,297,144...16,510,023

G

RNA pseudouridine synthase domain containing 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:704,649...708,025
Ensembl chr 5:704,519...708,058

G

regulator of telomere elongation helicase 1

susceptibility

ISO

DNA:SNP:cds:rs2297441|rs3208008 (human)

NCBI chr 2:531,905...567,430
Ensembl chr 2:531,085...566,840

G

rubicon like autophagy enhancer

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:24,400,507...24,445,514
Ensembl chr 3:24,399,500...24,430,601

G

RUN domain containing 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:63,297,669...63,313,397
Ensembl chr16:63,299,545...63,313,306

G

S100 calcium binding protein A3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:10,249,332...10,256,671
Ensembl chr20:10,255,515...10,256,318

G

scaffold attachment factor B2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:5,244,072...5,281,053
Ensembl chr 6:5,244,000...5,280,932

G

strawberry notch homolog 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:118,633,151...118,702,472
Ensembl chr11:118,634,332...118,677,415

G

sodium channel epithelial 1 subunit alpha

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:6,384,073...6,418,620
Ensembl chr11:6,383,956...6,416,337

G

secernin 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr21:28,386,910...28,456,556
Ensembl chr21:28,408,528...28,456,558

G

signal peptide, CUB domain and EGF like domain containing 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:36,871,032...36,910,583
Ensembl chr17:36,875,410...36,910,091

G

sidekick cell adhesion molecule 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr28:17,354,106...18,316,238
Ensembl chr28:17,351,241...17,998,205

G

serpin family B member 13

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr18:16,163,247...16,175,953
Ensembl chr18:16,165,054...16,173,438

G

SET domain containing 5

severity

ISO

NCBI chr22:45,391,871...45,475,183
Ensembl chr22:45,430,660...45,475,217

G

SET domain bifurcated histone lysine methyltransferase 1

ISO

mRNA, protein:increased expression:prostate gland (human)

G

seizure related 6 homolog like

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:9,069,476...9,284,540
Ensembl chr19:9,069,746...9,284,543

G

splicing factor 3b subunit 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:53,673,443...53,724,485
Ensembl chr 5:53,673,455...53,725,615

G

serum/glucocorticoid regulated kinase family member 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:62,587,494...62,732,766
Ensembl chr 8:62,647,303...62,732,868

G

small G protein signaling modulator 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:1,970,412...2,012,417
Ensembl chr16:1,970,456...2,014,384

G

SHC binding and spindle associated 1 like

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:46,424,943...46,473,336
Ensembl chr25:46,426,312...46,473,218

G

sucrase-isomaltase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:24,480,060...24,582,468
Ensembl chr15:24,482,865...24,582,394

G

sialic acid binding Ig like lectin 6

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:44,367,499...44,405,288
Ensembl chr 6:44,367,624...44,382,790

G

sirtuin 1

disease_progression

ISO

NCBI chr 9:63,463,059...63,497,893
Ensembl chr 9:63,462,389...63,497,867

G

SKI3 subunit of superkiller complex

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:89,346,960...89,438,260
Ensembl chr 4:89,344,526...89,430,070

G

SKI like proto-oncogene

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:19,022,167...19,059,117
Ensembl chr15:19,022,017...19,057,004

G

S-phase kinase associated protein 2

disease_progression

ISO

NCBI chr 4:35,009,114...35,040,518
Ensembl chr 4:35,009,076...35,042,632

G

solute carrier family 13 member 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:25741868 PMID:28492532

NCBI chr 2:17,233,287...17,324,761
Ensembl chr 2:17,233,346...17,324,951

G

solute carrier family 16 member 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:64,023,846...64,123,428
Ensembl chr X:64,023,327...64,125,422

G

solute carrier family 25 member 22

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:593,914...601,603
Ensembl chr 1:593,890...598,585

G

solute carrier family 25 member 32

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:98,256,793...98,271,347
Ensembl chr 8:98,254,852...98,271,514

G

solute carrier family 25 member 47

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:78,285,089...78,292,562
Ensembl chr24:78,285,593...78,292,773

G

SLC2A4 regulator

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:487,282...490,957
Ensembl chr 2:483,483...490,435

G

solute carrier family 30 member 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:106,722,539...106,731,494
Ensembl chr20:106,724,256...106,731,955

G

solute carrier family 34 member 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr23:79,395,923...79,410,835
Ensembl chr23:79,396,250...79,411,695

G

solute carrier family 35 member C1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:19,534,437...19,541,990
Ensembl chr 1:19,530,466...19,541,551

G

solute carrier family 35 member G1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:87,127,367...87,137,526

G

solute carrier family 46 member 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:7,802,170...7,819,608
Ensembl chr 3:7,801,728...7,819,584

G

solute carrier family 5 member 2

ISO

ClinVar Annotator: match by term: Prostate cancer

PMID:23265383 PMID:25741868

NCBI chr 5:28,183,141...28,191,352
Ensembl chr 5:28,183,618...28,191,120

G

solute carrier family 5 member 7

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:11,346,281...11,373,754
Ensembl chr14:11,347,861...11,370,297

G

solute carrier family 6 member 9

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr20:88,774,354...88,809,726
Ensembl chr20:88,774,339...88,808,669

G

solute carrier family 8 member A3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:47,287,487...47,428,608
Ensembl chr24:47,288,256...47,427,776

G

solute carrier organic anion transporter family member 1B3

disease_progression

ISO

mRNA,protein:increased expression:prostate (human)

NCBI chr11:20,637,429...20,760,577
Ensembl chr11:20,648,582...20,761,161

G

SMAD family member 3

disease_progression

ISO

protein:increased expression:tumor:significantly elevated in 53/67 (79%, p=0.0002) overall, in 23/35 with Gleason score 6-7(66%) and 30/32 with Gleason score 8-10 (94%, p=0.0062); by immunohistochemistry

NCBI chr26:16,319,959...16,446,472
Ensembl chr26:16,320,933...16,446,527

G

SMAD family member 9

ISO

protein:altered localization

NCBI chr 3:15,369,119...15,444,599
Ensembl chr 3:15,372,933...15,405,836

G

SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2

disease_progression

ISO

NCBI chr12:77,364,468...77,546,356
Ensembl chr12:77,375,500...77,546,314

G

SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4

no_association
disease_progression

ISO

absence of somatic mutations in the samples used

PMID:12684665 PMID:17075831

RGD:2302527 RGD:2302528

NCBI chr 6:9,943,162...10,044,476

G

SWI/SNF related BAF chromatin remodeling complex subunit C2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:52,103,075...52,131,070
Ensembl chr11:52,104,345...52,131,079

G

single-strand-selective monofunctional uracil-DNA glycosylase 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:50,292,780...50,307,828
Ensembl chr11:50,289,154...50,300,492

G

small nuclear ribonucleoprotein polypeptide E

severity

ISO

mRNA:increased expression:prostate gland (human)

NCBI chr25:25,474,620...25,483,427

G

suppressor of cytokine signaling 1

ISO

DNA:hypermethylation

NCBI chr 5:10,731,866...10,733,745
Ensembl chr 5:10,732,350...10,732,991

G

sorbin and SH3 domain containing 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:88,475,783...88,729,912
Ensembl chr 9:88,472,946...88,729,851

G

sortilin related VPS10 domain containing receptor 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:99,581,375...100,171,637

G

SOS Ras/Rac guanine nucleotide exchange factor 1

ISO

NCBI chr14:68,259,509...68,404,167
Ensembl chr14:68,259,360...68,399,895

G

SRY-box transcription factor 9

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:49,519,749...49,523,967
Ensembl chr16:49,518,185...49,523,898

G

spermatogenesis associated 18

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:16,342,176...16,388,458
Ensembl chr 7:16,340,607...16,387,995

G

sperm antigen with calponin homology and coiled-coil domains 1 like

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:7,488,821...7,539,961
Ensembl chr19:7,488,832...7,539,952

G

serine peptidase inhibitor Kazal type 1

severity

ISO

protein:increased expression:prostate gland, serum

NCBI chr23:50,365,686...50,373,300
Ensembl chr23:50,365,269...50,372,814

G

speckle type BTB/POZ protein

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:25741868

NCBI chr16:69,990,554...70,073,241

G

SRC proto-oncogene, non-receptor tyrosine kinase

disease_progression

ISO

protein:increased tyrosine phosphorylation:prostate gland, membrane

NCBI chr 2:26,344,480...26,367,448
Ensembl chr 2:26,343,450...26,367,776

G

steroid 5 alpha-reductase 1

disease_progression

ISO

protein:increased expression:prostate gland
mRNA:increased expression:prostate gland (rat)

PMID:16818707 PMID:17720776

RGD:2302521 RGD:2302523

NCBI chr 4:6,312,770...6,348,449
Ensembl chr 4:6,312,757...6,350,550

G

steroid 5 alpha-reductase 2

susceptibility

ISO

DNA:missense mutation:cds:p.A49T (human)
mRNA:decreased expression:prostate gland

PMID:10501358 PMID:12949937

RGD:2302560 RGD:4891929

NCBI chr14:75,915,495...75,971,280
Ensembl chr14:75,917,260...75,970,365

G

sterol regulatory element binding transcription factor 2

disease_progression

ISO

NCBI chr19:24,364,725...24,439,851
Ensembl chr19:24,364,911...24,440,014

G

single stranded DNA binding protein 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:75,561,872...75,882,924
Ensembl chr 4:75,562,625...75,882,845

G

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:17,269,548...17,400,860

G

signal transducer and activator of transcription 3

treatment

ISO

NCBI chr16:63,877,884...63,957,894
Ensembl chr16:63,922,862...63,957,984

G

signal transducer and activator of transcription 5A

disease_progression

ISO

DNA:CNV: :prostate (human)

NCBI chr16:63,959,265...63,986,627
Ensembl chr16:63,960,515...63,985,026

G

signal transducer and activator of transcription 6

disease_progression

ISO

mRNA, protein:increased expression:fibromuscular stroma, malignant epithelia:correlated with high histological grade and increased tumor size

NCBI chr11:53,005,378...53,020,899
Ensembl chr11:53,006,145...53,021,203

G

syntaxin 8

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:8,613,551...8,937,428

G

syntaxin binding protein 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:10,440,061...10,519,798
Ensembl chr12:10,439,801...10,519,777

G

SUFU negative regulator of hedgehog signaling

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr 9:95,532,228...95,660,594
Ensembl chr 9:95,532,242...95,657,290

G

sulfotransferase family 1A member 1

no_association

ISO

DNA:SNP:CDS:no association with the 638G->A, amino acid R213H polymorphism in a Japanese population
DNA, protein:SNP, increased activity:CDS:SULT1A1*1 high activity allele associated with higher prostate cancer risk, risk increases with increased consumption of well-done meat

PMID:14973106 PMID:18368507

RGD:1581454 RGD:2301050

NCBI chr 5:26,439,618...26,452,997

G

sulfotransferase family 2A member 1

no_association
severity

ISO

DNA:missense mutations:cds:p.A63P (187G>C), p.A261T (781G>A) (human)
DNA:SNP:intron: (rs2547238) (human)

PMID:16617014 PMID:22542949

RGD:6893648 RGD:6893649

NCBI chr 6:41,160,707...41,175,382
Ensembl chr 6:41,159,978...41,175,300

G

synaptic vesicle glycoprotein 2B

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr29:9,691,421...9,875,657
Ensembl chr29:9,806,570...9,872,782

G

synaptonemal complex protein 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:4,214,713...4,283,451
Ensembl chr 2:4,226,063...4,282,751

G

synaptogyrin 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:21,924,110...21,957,453
Ensembl chr19:21,924,174...21,953,808

G

TAO kinase 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:113,485,871...113,717,213
Ensembl chr11:113,484,330...113,704,271

G

transcription factor 3

severity

ISO

NCBI chr 6:1,393,147...1,440,515
Ensembl chr 6:1,393,107...1,440,479

G

transcription factor 7

severity

ISO

NCBI chr23:36,919,648...36,953,088
Ensembl chr23:36,919,745...36,951,192

G

transcription factor 7 like 2

disease_progression

ISO

DNA:SNP: :rs7903146 (human)
DNA:SNPs: :rs7094463, rs10749127, rs11196224 (human)

PMID:24961829 PMID:25678841

RGD:13506821 RGD:13506825

NCBI chr 9:105,828,834...106,047,810

G

telomerase reverse transcriptase

ISO

mRNA:increased expression:plasma

NCBI chr 4:1,082,894...1,119,373
Ensembl chr 4:1,083,384...1,117,468

G

testis expressed 14, intercellular bridge forming factor

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:34,709,039...34,849,855
Ensembl chr16:34,746,004...34,849,781

G

trefoil factor 1

disease_progression

ISO

mRNA:increased expression:prostate gland
protein:increased expression:plasma

PMID:10458410 PMID:16467092

RGD:2291999 RGD:2298571

NCBI chr 2:86,239,101...86,244,491
Ensembl chr 2:86,239,105...86,243,795

G

trefoil factor 2

disease_progression

ISO

protein:increased expression:plasma

NCBI chr 2:86,223,113...86,228,964

G

transferrin receptor

ISO

protein:increased expression:serum

NCBI chr15:91,102,153...91,134,994
Ensembl chr15:91,102,817...91,135,584

G

thyroglobulin

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:127,293,797...127,567,218
Ensembl chr 8:127,293,834...127,567,771

G

transforming growth factor beta 1

ISO

protein:increased expression:prostate gland

NCBI chr 6:35,651,583...35,674,387
Ensembl chr 6:35,648,677...35,674,365

G

transforming growth factor beta receptor 2

ISO

OMIM:176807 | OMIM:300147 | OMIM:300704 | OMIM:601518 | OMIM:602759 | OMIM:608656 | OMIM:608658 | OMIM:609299 | OMIM:609558 | OMIM:610321 | OMIM:610997 | OMIM:611100 | OMIM:611868 | OMIM:611928 | OMIM:611955 | OMIM:611958 | OMIM:611959

NCBI chr15:75,112,903...75,200,263
Ensembl chr15:75,112,561...75,197,711

G

transforming growth factor beta receptor 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:41,353,182...41,565,357
Ensembl chr20:41,353,325...41,565,343

G

thrombospondin 1

ISO

mRNA:decreased expression:prostate gland

NCBI chr26:43,410,693...43,427,816
Ensembl chr26:43,410,580...43,427,812

G

thrombospondin 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:8,621,706...8,640,252
Ensembl chr20:8,622,812...8,640,532

G

thyroid hormone receptor beta

ISO

DNA:loss of heterozygosity (human)

NCBI chr15:68,797,410...69,161,256
Ensembl chr15:68,802,078...68,902,292

G

TIMP metallopeptidase inhibitor 2

disease_progression

ISO

DNA, protein:hypermethylation, decreased expression:promoter, prostate gland
protein:increased expression:prostate gland

PMID:17325663 PMID:18329693

RGD:2290389 RGD:2290397

NCBI chr16:70,819,591...70,850,471
Ensembl chr16:70,819,139...70,850,471

G

TIMP metallopeptidase inhibitor 3

disease_progression

ISO

mRNA:decreased expression:prostate gland

NCBI chr19:15,621,609...15,684,118
Ensembl chr19:15,622,431...15,680,449

G

TLE family member 5, transcriptional modulator

ISO

associated with metastasis;protein:decreased expression:prostate

NCBI chr 6:2,822,814...2,832,625

G

toll like receptor 2

susceptibility

ISO

DNA:deletion:promoter:−196_−174del (human)

NCBI chr 7:100,239,533...100,565,955
Ensembl chr 7:100,258,441...100,260,795

G

transmembrane and coiled-coil domains 5A

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr26:45,001,265...45,040,160
Ensembl chr26:45,023,323...45,038,035

G

transmembrane protein with EGF like and two follistatin like domains 2

disease_progression

ISO

DNA:hypermethylation

PMID:15299075 PMID:16458425 PMID:16500022

RGD:2290485 RGD:2290486 RGD:2290490

NCBI chr10:77,491,041...77,735,890
Ensembl chr10:77,490,095...77,735,849

G

transmembrane protein 183A

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:26,329,213...26,346,850
Ensembl chr25:26,328,841...26,346,750

G

transmembrane protein 230

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:32,955,522...32,968,578
Ensembl chr 2:32,955,538...32,969,152

G

transmembrane protein 94

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:46,178,237...46,223,931
Ensembl chr16:46,177,181...46,202,463

G

tumor necrosis factor

ISO

G

TNF receptor superfamily member 8

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:119,656,183...119,736,151
Ensembl chr20:119,657,614...119,715,078

G

DNA topoisomerase II alpha

ISO

NCBI chr16:65,761,391...65,792,041
Ensembl chr16:65,761,416...65,792,701

G

TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:47,702,638...47,714,309
Ensembl chr12:47,702,995...47,714,338

G

tumor protein p53

disease_progression

ISO

DNA:mutations:exon
ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: Prostate cancer

PMID:1467311 PMID:1565144 PMID:2750177 PMID:7887414 PMID:7969167 More...

NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223

G

tumor protein p63

ISO

ClinVar Annotator: match by term: Prostate cancer

PMID:23265383 PMID:28492532

NCBI chr15:83,861,489...84,126,675

G

tumor protein p73

ISO

mRNA:alternative forms

NCBI chr20:127,958,002...128,035,792
Ensembl chr20:127,958,809...128,013,691

G

tripartite motif containing 28

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:50,820,188...50,826,376
Ensembl chr 6:50,819,833...50,827,010

G

tripartite motif containing 5

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:61,040,908...61,067,815
Ensembl chr 1:61,040,928...61,069,356

G

tripartite motif family like 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:133,998,623...134,009,606
Ensembl chr 7:134,001,323...134,009,241

G

thyroid hormone receptor interactor 12

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:115,789,978...115,946,978
Ensembl chr10:115,789,605...115,945,753

G

transient receptor potential cation channel subfamily C member 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:47,827,295...47,909,207
Ensembl chr15:47,827,247...47,909,202

G

transient receptor potential cation channel subfamily C member 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:16,135,822...16,358,902

G

transient receptor potential cation channel subfamily M member 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:81,608,301...82,616,349
Ensembl chr12:81,609,229...81,925,984

G

transformation/transcription domain associated protein

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr28:14,154,962...14,289,110
Ensembl chr28:14,154,960...14,286,512

G

tumor susceptibility 101

ISO

mRNA:alternative forms:cds:multiple

NCBI chr 1:46,401,889...46,451,122
Ensembl chr 1:46,402,024...46,450,916

G

teashirt zinc finger homeobox 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:26,334,239...26,409,597

G

translin associated factor X interacting protein 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:59,611,229...59,631,212
Ensembl chr 5:59,609,692...59,630,985

G

tetraspanin 5

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:46,610,841...46,788,761
Ensembl chr 7:46,609,602...46,788,704

G

tubulin beta 3 class III

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:75,242,423...75,257,992
Ensembl chr 5:75,246,614...75,258,084

G

unc-51 like autophagy activating kinase 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:18,335,095...18,434,031
Ensembl chr16:18,335,235...18,433,578

G

uromodulin like 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 2:85,894,102...86,023,577
Ensembl chr 2:85,959,746...86,019,950

G

unc-79 homolog, NALCN channel complex subunit

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr24:71,172,214...71,455,415
Ensembl chr24:71,209,614...71,456,568

G

URB2 ribosome biogenesis homolog

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:66,893,033...66,926,921
Ensembl chr25:66,893,112...66,929,487

G

upstream transcription factor 2, c-fos interacting

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:30,202,224...30,212,783
Ensembl chr 6:30,202,375...30,213,058

G

usherin

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:13,171,499...13,950,553
Ensembl chr25:13,173,576...13,947,724

G

ubiquitin specific peptidase 28

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:105,175,116...105,257,163
Ensembl chr 1:105,175,067...105,257,102

G

ubiquitin specific peptidase 48

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:110,854,966...110,958,140
Ensembl chr20:110,854,758...110,960,529

G

UV radiation resistance associated

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:67,032,575...67,353,207
Ensembl chr 1:67,032,436...67,353,166

G

versican

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr 4:77,581,627...77,692,495
Ensembl chr 4:77,593,449...77,690,616

G

voltage dependent anion channel 1

ISO

DNA:SNP: :rs7250897 (human)

NCBI chr23:36,783,670...36,817,071

G

vitamin D receptor

susceptibility

ISO

DNA:SNP: :rs11574143 (human)

NCBI chr11:44,062,198...44,126,295
Ensembl chr11:44,065,457...44,166,684

G

vascular endothelial growth factor A

ISO

NCBI chr17:28,377,959...28,394,508

G

vitamin K epoxide reductase complex subunit 1 like 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr28:1,535,346...1,617,484

G

WD repeat and FYVE domain containing 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:33,031,762...33,331,475
Ensembl chr 7:33,030,069...33,237,701

G

WD repeat domain 49

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:21,778,500...21,967,551

G

WAP four-disulfide core domain 1

disease_progression

ISO

mRNA:decreased expression:prostate gland
protein:decreased expression, increased expression:connective tissue, epithelium

PMID:15305341 PMID:15305342

RGD:2291859 RGD:2291860

NCBI chr 5:69,700,984...69,734,682
Ensembl chr 5:69,701,470...69,731,823

G

WNT inhibitory factor 1

ISO

mRNA, protein:decreased expression:prostate gland

NCBI chr11:60,728,316...60,800,181
Ensembl chr11:60,727,948...60,799,960

G

Wnt family member 2

ISO

mRNA:decreased expression:prostate gland

NCBI chr21:85,955,517...86,005,664
Ensembl chr21:85,955,145...86,001,730

G

WWC family member 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:8,471,537...8,600,474
Ensembl chr X:8,471,578...8,600,516

G

X-linked inhibitor of apoptosis

disease_progression

ISO

protein:increased expression:prostate gland

PMID:17947468 PMID:19415464

RGD:2315849 RGD:2315852

G

X-ray repair cross complementing 1

susceptibility

ISO

DNA:polymorphism: :p.R399Q

NCBI chr 6:37,062,149...37,095,138
Ensembl chr 6:37,060,439...37,095,094

G

YTH N6-methyladenosine RNA binding protein C2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr23:16,800,515...16,880,983
Ensembl chr23:16,800,558...16,880,952

G

zDHHC palmitoyltransferase 8

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:5,591,311...5,607,448
Ensembl chr19:5,589,090...5,607,387

G

zinc finger homeobox 3

susceptibility

ISO

DNA, mRNA:mutations, decreased expression: :multiple, prostate gland (human)
DNA:deletion (human)

PMID:15750593 PMID:16637072

RGD:2315694 RGD:2315695

NCBI chr 5:55,912,325...56,174,010
Ensembl chr 5:55,907,983...56,085,112

G

zinc finger with KRAB and SCAN domains 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr28:13,013,603...13,064,154
Ensembl chr28:13,044,616...13,056,332

G

zinc finger matrin-type 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:10,374,093...10,434,212
Ensembl chr15:10,373,904...10,430,759

G

zinc finger protein 136

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:10,984,818...11,012,092

G

zinc finger protein 184

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:45,046,492...45,068,236
Ensembl chr17:45,061,170...45,071,256

G

zinc finger protein 224

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

G

zinc finger protein 287

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:15,087,895...15,107,194

G

zinc finger protein 304

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:49,754,839...49,763,281

G

zinc finger protein 48

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:27,069,694...27,074,692
Ensembl chr 5:27,070,309...27,074,731

G

zinc finger protein 560

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:8,632,432...8,675,720
Ensembl chr 6:8,632,708...8,641,252

G

zinc finger protein 772

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:49,856,459...49,862,922

G

zinc finger protein 776

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:50,123,668...50,135,933

G

zona pellucida glycoprotein 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr25:75,002,053...75,010,764
Ensembl chr25:75,002,344...75,010,323

G

zinc finger and SCAN domain containing 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr29:3,746,183...3,770,586
Ensembl chr29:3,744,923...3,769,890

castration-resistant prostate carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aldo-keto reductase family 1 member C3

ISO

CTD Direct Evidence: marker/mechanism
mRNA,protein:increased expression:epithelial cell:

PMID:23196782 PMID:25555457

NCBI chr 9:5,237,176...5,254,772

G

androgen receptor

ISO

CTD Direct Evidence: marker/mechanism

PMID:18985049 PMID:24740322 PMID:28500234 PMID:28757136

NCBI chr X:57,380,587...57,553,613
Ensembl chr X:57,380,611...57,546,776

G

anti-silencing function 1B histone chaperone

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 6:12,760,865...12,773,423

G

cyclin E2

treatment

ISO

NCBI chr 8:89,846,670...89,863,432
Ensembl chr 8:89,848,077...89,862,037

G

CD46 molecule

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr25:21,650,825...21,693,898
Ensembl chr25:21,655,969...21,693,878

G

centromere protein K

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 4:61,712,006...61,755,082
Ensembl chr 4:61,712,043...61,747,178

G

chromodomain helicase DNA binding protein 1

ISO

DNA:mutations: :

NCBI chr23:2,433,694...2,507,334
Ensembl chr23:2,432,461...2,507,704

G

lysine demethylase 1A

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr20:109,592,761...109,657,885
Ensembl chr20:109,593,074...109,657,839

G

transcription intermediary factor 1-alpha

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr21:107,166,180...107,291,897
Ensembl chr21:107,166,395...107,295,736

G

NUF2 component of NDC80 kinetochore complex

treatment

ISO

NCBI chr25:65,462,608...65,493,242
Ensembl chr25:65,462,603...65,493,246

G

signal transducer and activator of transcription 5A

treatment
disease_progression

ISO

DNA:CNV: :prostate (human)

NCBI chr16:63,959,265...63,986,627
Ensembl chr16:63,960,515...63,985,026

G

zinc finger protein 217

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 2:10,427,584...10,455,308
Ensembl chr 2:10,439,082...10,450,670

G

zinc finger protein 367

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr12:106,712,962...106,743,351
Ensembl chr12:106,713,310...106,741,040

Familial Prostate Cancer

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adhesion G protein-coupled receptor G1

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 5:43,559,792...43,595,906
Ensembl chr 5:43,570,189...43,596,087

G

androgen receptor

ISO

ClinVar Annotator: match by term: Prostate cancer susceptibility

PMID:8530589 PMID:10589774 PMID:11103816 PMID:28492532

NCBI chr X:57,380,587...57,553,613
Ensembl chr X:57,380,611...57,546,776

G

alpha tubulin acetyltransferase 1

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr17:41,807,405...41,830,670
Ensembl chr17:41,807,291...41,830,000

G

ATM serine/threonine kinase

ISO

ClinVar Annotator: match by term: Familial prostate cancer

PMID:15928302 PMID:16941484 PMID:17124347 PMID:17910737 PMID:19431188 More...

NCBI chr 1:99,653,208...99,786,889
Ensembl chr 1:99,653,139...99,791,520

G

beta-1,3-glucuronyltransferase 1

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 1:125,449,162...125,490,208
Ensembl chr 1:125,448,500...125,490,192

G

brain enriched myelin associated protein 1

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 2:9,972,244...10,098,126
Ensembl chr 2:9,972,433...10,096,747

G

BCL2 apoptosis regulator

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895

G

BCL2 like 11

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr14:14,178,159...14,205,337

G

bridge-like lipid transfer protein family member 3A

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr17:37,241,841...37,322,220
Ensembl chr17:37,246,908...37,321,337

G

BRCA1 DNA repair associated

ISO

ClinVar Annotator: match by term: Familial prostate cancer

PMID:17319787 PMID:18489799 PMID:20104584 PMID:21203900 PMID:25525159 More...

NCBI chr16:63,162,827...63,243,928

G

BRCA2 DNA repair associated

ISO

ClinVar Annotator: match by term: Familial prostate cancer | ClinVar Annotator: match by term: Hereditary Prostate Cancer | ClinVar Annotator: match by term: Hereditary prostate cancer

PMID:186727 PMID:251866 PMID:8075631 PMID:8524414 PMID:8589730 More...

NCBI chr 3:11,070,086...11,155,257
Ensembl chr 3:11,071,682...11,155,213

G

chromosome 1 C11orf65 homolog

ISO

ClinVar Annotator: match by term: Familial prostate cancer

PMID:15928302 PMID:16941484 PMID:17124347 PMID:17910737 PMID:19431188 More...

NCBI chr 1:99,804,191...99,879,834
Ensembl chr 1:99,804,218...99,827,182

G

caspase 8

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr10:86,888,654...86,944,159
Ensembl chr10:86,916,527...86,943,829

G

cell division cycle associated 7

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr10:58,847,319...58,859,843
Ensembl chr10:58,848,781...58,859,845

G

cadherin 1

ISO

ClinVar Annotator: match by term: Hereditary prostate cancer | ClinVar Annotator: match by term: Prostate cancer susceptibility

PMID:11948460 PMID:14961571 PMID:15235021 PMID:16061854 PMID:16189707 More...

NCBI chr 5:58,578,244...58,679,677
Ensembl chr 5:58,578,146...58,679,541

G

cyclin dependent kinase inhibitor 1B

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr11:12,612,064...12,617,228
Ensembl chr11:12,612,079...12,617,531

G

chromodomain helicase DNA binding protein 3

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr16:7,274,634...7,300,831
Ensembl chr16:7,276,850...7,300,832

G

checkpoint kinase 2

ISO

ClinVar Annotator: match by term: Familial prostate cancer | ClinVar Annotator: match by term: Hereditary Prostate Cancer | ClinVar Annotator: match by term: Hereditary prostate cancer | ClinVar Annotator: match by term: Prostate cancer susceptibility

PMID:9536098 PMID:10617473 PMID:11053450 PMID:11298456 PMID:11390408 More...

NCBI chr19:11,567,529...11,621,180
Ensembl chr19:11,567,528...11,604,792

G

collagen type XXIII alpha 1 chain

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr23:79,932,340...80,279,808

G

cytochrome P450 family 3 subfamily A member 4

no_association

ISO

NCBI chr28:13,297,566...13,330,023

G

DENN domain containing 4B

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr20:9,865,833...9,882,259
Ensembl chr20:9,868,106...9,881,465

G

DNA methyltransferase 3 beta

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 2:37,128,635...37,176,033
Ensembl chr 2:37,146,538...37,174,570

G

dedicator of cytokinesis 2

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr23:71,866,196...72,299,066
Ensembl chr23:71,866,251...72,299,056

G

EMSY transcriptional repressor, BRCA2 interacting

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 1:67,657,747...67,762,157
Ensembl chr 1:67,657,753...67,760,610

G

fibrosin like 1

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr11:127,840,826...127,936,739

G

homeobox B13

ISO

ClinVar Annotator: match by term: Prostate cancer susceptibility

PMID:8756292 PMID:15964834 PMID:17138648 PMID:22236224 PMID:22714738 More...

NCBI chr16:69,137,561...69,141,615
Ensembl chr16:69,137,585...69,139,382

G

inner centromere protein

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 1:11,695,803...11,725,633
Ensembl chr 1:11,692,559...11,720,940

G

integrin subunit beta 8

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr21:37,811,811...37,896,539
Ensembl chr21:37,817,572...37,895,560

G

lysine demethylase 2A

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 1:7,004,109...7,152,072
Ensembl chr 1:7,003,784...7,082,720

G

kinetochore scaffold 1

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr26:42,342,741...42,409,466

G

La ribonucleoprotein 4B

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 9:778,786...898,263

G

long intergenic non-protein coding RNA 3103

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 6:26,646,904...26,648,574

G

mitotic arrest deficient 1 like 1

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr28:19,358,942...19,768,079
Ensembl chr28:19,359,233...19,768,078

G

mitogen-activated protein kinase kinase 1

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr26:17,059,122...17,168,787
Ensembl chr26:17,060,054...17,168,782

G

methyl-CpG binding domain protein 2

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr18:26,714,610...26,785,028

G

muscleblind like splicing regulator 1

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr15:38,208,694...38,427,867
Ensembl chr15:38,208,038...38,375,273

G

MDS1 and EVI1 complex locus

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr15:19,726,423...20,320,832
Ensembl chr15:20,256,384...20,320,834

G

major histocompatibility complex, class II, DO alpha

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr17:39,084,785...39,090,477
Ensembl chr17:39,085,080...39,090,474

G

matrix metallopeptidase 14

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr29:23,201,425...23,212,408
Ensembl chr29:23,201,112...23,212,679

G

MOB kinase activator 2

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 1:1,267,041...1,338,940
Ensembl chr 1:1,266,952...1,338,895

G

mutS homolog 6

ISO

ClinVar Annotator: match by term: Hereditary prostate cancer

PMID:18269114 PMID:24362816 PMID:25741868 PMID:28492532

NCBI chr14:59,375,602...59,400,252
Ensembl chr14:59,375,691...59,400,174

G

myosin IXB

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 6:15,571,276...15,707,571
Ensembl chr 6:15,596,583...15,707,567

G

nibrin

ISO

ClinVar Annotator: match by term: Hereditary Prostate Cancer

PMID:9590180 PMID:9590181 PMID:9620777 PMID:10398434 PMID:10799436 More...

NCBI chr 8:85,017,807...85,069,219
Ensembl chr 8:85,015,752...85,069,028

G

paired box 9

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr24:13,454,839...13,470,564
Ensembl chr24:13,455,589...13,473,505

G

PBX/knotted 1 homeobox 2

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 1:116,332,851...116,604,758
Ensembl chr 1:116,523,593...116,605,161

G

POU class 2 homeobox 2

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 6:36,292,252...36,382,354
Ensembl chr 6:36,295,275...36,336,013

G

PPFIA binding protein 2

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 1:57,182,518...57,326,875
Ensembl chr 1:57,182,327...57,289,827

G

phosphatase and tensin homolog

ISO

ClinVar Annotator: match by term: Hereditary Prostate Cancer

PMID:12844284 PMID:12938083 PMID:17847000 PMID:21194675 PMID:21956414 More...

NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146

G

Ras association domain family member 3

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr11:60,289,751...60,374,220
Ensembl chr11:60,289,680...60,375,600

G

regulatory factor X7

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr26:27,248,814...27,399,385

G

ribonuclease L

ISO

ClinVar Annotator: match by term: Prostate cancer susceptibility

PMID:12415269 PMID:16609730 PMID:25741868

NCBI chr25:46,779,221...46,795,854
Ensembl chr25:46,779,700...46,795,842

G

ring finger protein 43

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr16:34,981,126...35,046,478
Ensembl chr16:34,980,922...35,045,107

G

renalase, FAD dependent amine oxidase

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 9:81,725,115...82,029,361

G

succinyl-CoA:glutarate-CoA transferase

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr21:17,621,886...18,511,591
Ensembl chr21:18,151,535...18,511,310

G

transcription factor 4

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr18:24,116,595...24,483,037
Ensembl chr18:24,116,547...24,478,228

G

transcription factor 7 like 2

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 9:105,828,834...106,047,810

G

torsin family 1 member A

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr12:8,312,652...8,323,932
Ensembl chr12:8,312,650...8,322,907

G

teashirt zinc finger homeobox 1

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr18:4,622,407...4,702,267
Ensembl chr18:4,623,731...4,626,925

G

tetratricopeptide repeat domain 28

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr19:10,883,566...11,559,332
Ensembl chr19:10,887,702...11,334,237

prostate adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adiponectin, C1Q and collagen domain containing

susceptibility

ISO

DNA:SNPs, haplotypes:5' utr, introns, exon:multiple

NCBI chr15:81,128,427...81,142,779
Ensembl chr15:81,129,795...81,147,391

G

adiponectin receptor 1

susceptibility

ISO

DNA:SNPs, haplotype:intron, exon: (rs12733285, rs7539452) (human)

NCBI chr25:26,445,993...26,462,346
Ensembl chr25:26,453,242...26,462,549

G

AKT serine/threonine kinase 1

treatment

ISO

NCBI chr24:82,704,087...82,730,711
Ensembl chr24:82,704,068...82,727,698

G

AKT serine/threonine kinase 2

treatment

ISO

NCBI chr 6:34,688,585...34,740,458
Ensembl chr 6:34,690,462...34,720,781

G

AKT serine/threonine kinase 3

treatment

ISO

NCBI chr25:80,509,701...80,878,792
Ensembl chr25:80,515,168...80,816,018

G

androgen receptor

treatment

ISO

NCBI chr X:57,380,587...57,553,613
Ensembl chr X:57,380,611...57,546,776

G

bridging integrator 1

ISO

NCBI chr10:3,112,605...3,173,522
Ensembl chr10:3,113,868...3,173,620

G

baculoviral IAP repeat containing 6

ameliorates

ISO

mRNA:increased expression:prostate gland (human)

NCBI chr14:74,879,597...75,138,462
Ensembl chr14:74,878,700...75,138,441

G

baculoviral IAP repeat containing 7

exacerbates

ISO

mRNALincreased expression:prostate gland (human)

NCBI chr 2:965,811...970,983

G

B-Raf proto-oncogene, serine/threonine kinase

ISO

NCBI chr21:109,495,525...109,690,261

G

calcium/calmodulin dependent protein kinase II inhibitor 1

treatment

ISO

NCBI chr20:112,064,718...112,068,505
Ensembl chr20:112,065,581...112,067,256

G

cyclin B1

severity

ISO

NCBI chr 4:65,265,798...65,276,465
Ensembl chr 4:65,265,844...65,277,085

G

cyclin E2

ISO

NCBI chr 8:89,846,670...89,863,432
Ensembl chr 8:89,848,077...89,862,037

G

CD9 molecule

disease_progression

ISO

DNA, mRNA:deletion, point mutation, decreased expression:prostate gland

NCBI chr11:6,236,449...6,275,904
Ensembl chr11:6,236,494...6,275,909

G

chromodomain helicase DNA binding protein 4

ISO

mRNA:decreased expression:prostate gland (human)

NCBI chr11:6,603,820...6,641,278
Ensembl chr11:6,602,694...6,640,351

G

component of inhibitor of nuclear factor kappa B kinase complex

treatment

ISO

NCBI chr 9:93,219,374...93,263,077
Ensembl chr 9:93,219,383...93,262,700

G

clusterin

treatment

ISO

NCBI chr 8:25,704,441...25,721,789
Ensembl chr 8:25,703,257...25,721,789

G

cAMP responsive element binding protein 3 like 4

ISO

PMID:11830526 PMID:17270658

RGD:13504714 RGD:13504715

NCBI chr20:9,839,137...9,848,413
Ensembl chr20:9,838,085...9,845,287

G

catenin beta 1

ISO

ClinVar Annotator: match by term: Prostate adenocarcinoma

PMID:10192393 PMID:25741868 PMID:26619011

NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949

G

DNA methyltransferase 1

ISO

mRNA,protein:increased expression:prostate gland:

NCBI chr 6:9,199,006...9,263,890
Ensembl chr 6:9,199,003...9,263,607

G

DNA methyltransferase 3 alpha

ISO

mRNA:increased expression:prostate gland:

NCBI chr14:82,313,414...82,427,170
Ensembl chr14:82,402,826...82,420,819

G

DNA methyltransferase 3 beta

ISO

mRNA,protein:increased expression:prostate gland:

NCBI chr 2:37,128,635...37,176,033
Ensembl chr 2:37,146,538...37,174,570

G

fibroblast growth factor 2

disease_progression

ISO

NCBI chr 7:70,089,394...70,157,423

G

fibroblast growth factor receptor 1

ISO

PMID:18068632 PMID:23576558

RGD:13504748 RGD:2298702

NCBI chr 8:36,426,116...36,485,683
Ensembl chr 8:36,427,110...36,485,508

G

growth factor receptor bound protein 2

ISO

NCBI chr16:46,264,818...46,346,426
Ensembl chr16:46,264,825...46,347,156

G

HRas proto-oncogene, GTPase

ISO

ClinVar Annotator: match by term: Adenocarcinoma of prostate | ClinVar Annotator: match by term: Prostate adenocarcinoma

PMID:1904555 PMID:3510078 PMID:11150980 PMID:16155195 PMID:16170316 More...

NCBI chr 1:343,613...345,782
Ensembl chr 1:343,506...346,637

G

isocitrate dehydrogenase (NADP(+)) 1

ISO

ClinVar Annotator: match by term: Prostate adenocarcinoma

PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20946881 More...

NCBI chr10:94,021,002...94,039,997
Ensembl chr10:94,020,818...94,039,975

G

insulin like growth factor 1 receptor

treatment
disease_progression

ISO

PMID:8692980 PMID:25442907 PMID:25862373 PMID:26452103

RGD:13504753 RGD:13504767 RGD:13504768 RGD:13504771

NCBI chr29:17,212,206...17,534,036
Ensembl chr29:17,459,404...17,526,930

G

inhibitor of nuclear factor kappa B kinase subunit beta

treatment

ISO

NCBI chr 8:40,267,532...40,325,282
Ensembl chr 8:40,268,079...40,326,381

G

integrin linked kinase

disease_progression

ISO

protein:increased expression:tumor: high-grade tumors versus adjacent BHP (P<0.001), BHP from cancer-free patients (P<0.002), or low-grade tumors (P=0.003), also associated with proliferative index (P=0.001), but inversely related to 5-year survival (p=0.004)

NCBI chr 1:58,214,630...58,221,770
Ensembl chr 1:58,213,310...58,221,217

G

insulin receptor

treatment

ISO

NCBI chr 6:6,625,951...6,803,610
Ensembl chr 6:6,630,777...6,803,592

G

Jun proto-oncogene, AP-1 transcription factor subunit

disease_progression

ISO

protein:increased expression, increased activation:significantly higher levels in invading vs organ-confined specimens (P<0.001)

NCBI chr20:74,204,481...74,207,835
Ensembl chr20:74,205,542...74,206,546

G

kinase insert domain receptor

ISO

protein:increased expression:tumor:relative to benign prostatic hypertrophy (BPH) tissue
protein:increased expression:prostate gland

PMID:17491265 PMID:20808233

RGD:2291925 RGD:5684541

NCBI chr 7:13,435,059...13,482,236
Ensembl chr 7:13,435,096...13,482,771

G

mitogen-activated protein kinase kinase 1

disease_progression

ISO

metastasis; inhibition reduced invasiveness of prostate tumor cells

NCBI chr26:17,059,122...17,168,787
Ensembl chr26:17,060,054...17,168,782

G

mitogen-activated protein kinase 1

treatment

ISO

PMID:22139534 PMID:28492138

RGD:13504818 RGD:13504820

NCBI chr19:4,246,144...4,352,648
Ensembl chr19:4,246,122...4,353,325

G

MYC proto-oncogene, bHLH transcription factor

ISO

human gene in mouse model

PMID:14522256 PMID:20195545

RGD:7207413 RGD:7207781

NCBI chr 8:122,282,989...122,288,392
Ensembl chr 8:122,282,630...122,288,384

G

nuclear receptor coactivator 2

ameliorates

ISO

human cells in mouse model

NCBI chr 8:65,855,232...66,151,733
Ensembl chr 8:65,855,235...66,040,947

G

NFKB inhibitor alpha

severity

ISO

protein:increased serine phosphorylation

PMID:15073126 PMID:15712212

RGD:13506768 RGD:2298768

NCBI chr24:12,211,619...12,216,185
Ensembl chr24:12,210,281...12,214,854

G

peptidylglycine alpha-amidating monooxygenase

ISO

mRNA:increased expression:prostate gland (human)

NCBI chr23:6,316,428...6,482,959
Ensembl chr23:6,316,428...6,486,751

G

platelet derived growth factor subunit A

ISO

protein:increased expression:prostate

NCBI chr28:21,044,549...21,068,411
Ensembl chr28:21,047,219...21,069,827

G

platelet derived growth factor receptor alpha

ISO

protein:increased expression:prostate

NCBI chr 7:14,243,291...14,307,373
Ensembl chr 7:14,241,070...14,307,422

G

3-phosphoinositide dependent protein kinase 1

treatment

ISO

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

ISO

ClinVar Annotator: match by term: Adenocarcinoma of prostate

PMID:15016963 PMID:15254419 PMID:15647370 PMID:15805248 PMID:18676830 More...

NCBI chr15:10,218,034...10,304,874
Ensembl chr15:10,218,805...10,294,316

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

treatment

ISO

NCBI chr15:51,705,585...51,885,848
Ensembl chr15:51,775,733...51,889,238

G

protein kinase C theta

ISO

mRNA:increased expression:prostate

NCBI chr 9:6,532,438...6,675,708
Ensembl chr 9:6,532,319...6,621,487

G

Raf-1 proto-oncogene, serine/threonine kinase

treatment

ISO

NCBI chr22:48,560,270...48,643,537
Ensembl chr22:48,561,161...48,618,020

G

RELA proto-oncogene, NF-kB subunit

disease_progression

ISO

protein:increased expression:prostate gland

PMID:15073126 PMID:15712212

RGD:13506768 RGD:2298768

NCBI chr 1:8,576,059...8,585,561
Ensembl chr 1:8,576,542...8,586,516

G

signal transducer and activator of transcription 1

disease_progression

ISO

protein:increased activity:prostate

NCBI chr10:76,492,859...76,537,689
Ensembl chr10:76,492,533...76,533,393

G

telomerase reverse transcriptase

treatment

ISO

NCBI chr 4:1,082,894...1,119,373
Ensembl chr 4:1,083,384...1,117,468

G

transmembrane serine protease 2

disease_progression

ISO

protein:increased expression, altered localization:prostate gland

NCBI chr 2:85,372,881...85,413,717
Ensembl chr 2:85,372,117...85,412,926

G

tumor protein p53

ISO

ClinVar Annotator: match by term: Prostate adenocarcinoma
ClinVar Annotator: match by term: Adenocarcinoma of prostate

PMID:1565143 PMID:1565144 PMID:11370630 PMID:12826609 PMID:19468865 More...

NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223

Prostate Cancer, Hereditary, 1

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

B-Raf proto-oncogene, serine/threonine kinase

ISO

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

PMID:12068308 PMID:15035987 PMID:16439621 PMID:17096326 PMID:17119447 More...

NCBI chr21:109,495,525...109,690,261

G

homeobox B13

ISO

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

PMID:9536098 PMID:17576681 PMID:25741868 PMID:26467025 PMID:28492532

NCBI chr16:69,137,561...69,141,615
Ensembl chr16:69,137,585...69,139,382

G

HRas proto-oncogene, GTPase

ISO

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

NCBI chr 1:343,613...345,782
Ensembl chr 1:343,506...346,637

G

KRAS proto-oncogene, GTPase

ISO

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

PMID:17056636 PMID:17468812 PMID:17704260 PMID:18386799 PMID:20949621 More...

NCBI chr11:24,963,396...25,010,747
Ensembl chr11:24,973,619...25,005,191

G

leucine rich repeat containing 56

ISO

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

NCBI chr 1:352,131...370,276
Ensembl chr 1:355,982...369,633

G

NRAS proto-oncogene, GTPase

ISO

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

NCBI chr20:18,953,273...18,966,002
Ensembl chr20:18,953,883...18,961,931

G

phosphatase and tensin homolog

ISO

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

PMID:9467011 PMID:9600246 PMID:10051160 PMID:12786840 PMID:16773562 More...

NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146

G

ribonuclease L

ISO

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1 | ClinVar Annotator: match by term: RNASEL-related condition

PMID:11799394 PMID:12415269 PMID:16609730 PMID:25741868 PMID:28492532

NCBI chr25:46,779,221...46,795,854
Ensembl chr25:46,779,700...46,795,842

G

tumor protein p53

ISO

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

PMID:12826609 PMID:20522432 PMID:25741868 PMID:27545002 PMID:28492532 More...

NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223

G

vascular endothelial growth factor A

ISO

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

NCBI chr17:28,377,959...28,394,508

Prostate Cancer, Hereditary, 12

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

EH domain binding protein 1

ISO

ClinVar Annotator: match by term: EHBP1-related condition | ClinVar Annotator: match by term: Prostate cancer, hereditary, 12

PMID:18264098 PMID:25741868

NCBI chr14:43,971,400...44,293,615
Ensembl chr14:43,971,261...44,292,365

Prostate Cancer, Hereditary, 13

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

microseminoprotein beta

ISO

ClinVar Annotator: match by term: Prostate cancer, hereditary, 13

PMID:18264096 PMID:18264097 PMID:19153072 PMID:19383797 PMID:19644707

NCBI chr 9:41,796,948...41,810,373
Ensembl chr 9:41,803,922...41,810,276

Prostate Cancer, Hereditary, 2

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

elaC ribonuclease Z 2

ISO

ClinVar Annotator: match by term: ELAC2-related condition | ClinVar Annotator: match by term: Prostate cancer, hereditary, 2

PMID:10986046 PMID:11175785 PMID:11254448 PMID:11507049 PMID:12515253 More...

NCBI chr16:12,328,864...12,353,916
Ensembl chr16:12,329,300...12,353,872

Prostate Cancer, Hereditary, 9

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

homeobox B13

ISO

ClinVar Annotator: match by term: HOXB13-related condition | ClinVar Annotator: match by term: Prostate cancer, hereditary, 9

PMID:8756292 PMID:15964834 PMID:17138648 PMID:22236224 PMID:22714738 More...

NCBI chr16:69,137,561...69,141,615
Ensembl chr16:69,137,585...69,139,382

Prostate Cancer, Hereditary, X-Linked 3

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

androgen receptor

ISO

ClinVar Annotator: match by term: Prostate cancer, hereditary, X-linked 3

PMID:17970778 PMID:23637914 PMID:25741868 PMID:27899157 PMID:28492532 More...

NCBI chr X:57,380,587...57,553,613
Ensembl chr X:57,380,611...57,546,776

Prostate Cancer, Somatic

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

androgen receptor

ISO

ClinVar Annotator: match by term: Prostate cancer, somatic

PMID:1631125 PMID:1779964 PMID:6541981 PMID:7723794 PMID:7795646 More...

NCBI chr X:57,380,587...57,553,613
Ensembl chr X:57,380,611...57,546,776

G

checkpoint kinase 2

ISO

ClinVar Annotator: match by term: Prostate cancer, somatic

PMID:12533788 PMID:16835864 PMID:16941491 PMID:18058223 PMID:18996005 More...

NCBI chr19:11,567,529...11,621,180
Ensembl chr19:11,567,528...11,604,792

G

KLF transcription factor 6

ISO

ClinVar Annotator: match by term: Prostate cancer, somatic

NCBI chr 9:3,872,376...3,881,238
Ensembl chr 9:3,875,356...3,881,229

G

mitotic arrest deficient 1 like 1

ISO

ClinVar Annotator: match by term: Prostate cancer, somatic

PMID:11423979 PMID:25741868

NCBI chr28:19,358,942...19,768,079
Ensembl chr28:19,359,233...19,768,078

G

phosphatase and tensin homolog

ISO

ClinVar Annotator: match by term: Prostate cancer, somatic

NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146

G

zinc finger homeobox 3

ISO

ClinVar Annotator: match by term: Prostate cancer, somatic

NCBI chr 5:55,912,325...56,174,010
Ensembl chr 5:55,907,983...56,085,112

Prostate Cancer/Brain Cancer Susceptibility

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

EPH receptor B2

susceptibility

ISO

ClinVar Annotator: match by term: Prostate cancer/brain cancer susceptibility

PMID:15300251 PMID:16155194 PMID:25741868 PMID:28492532

NCBI chr20:109,747,883...109,954,936
Ensembl chr20:109,746,925...109,890,777

prostate carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

AKT serine/threonine kinase 2

treatment

ISO

NCBI chr 6:34,688,585...34,740,458
Ensembl chr 6:34,690,462...34,720,781

G

angiopoietin 1

ISO

protein:increased expression:prostate gland

NCBI chr 8:102,020,346...102,268,443

G

activating transcription factor 4

treatment

ISO

NCBI chr19:22,092,046...22,094,184
Ensembl chr19:22,091,667...22,095,230

G

alpha-2-glycoprotein 1, zinc-binding

exacerbates

ISO

NCBI chr28:13,104,262...13,120,329
Ensembl chr28:13,104,323...13,120,363

G

BCL2 associated agonist of cell death

ISO

protein:increased expression:prostate gland

NCBI chr 1:9,949,717...9,964,433
Ensembl chr 1:9,949,762...9,964,432

G

BCL2 associated X, apoptosis regulator

disease_progression

ISO

protein:increased expression:prostate gland epithelium

NCBI chr 6:42,186,028...42,193,105

G

BCL2 like 1

ISO

NCBI chr 2:36,059,024...36,118,332
Ensembl chr 2:36,058,919...36,116,470

G

BCL2 like 14

ISO

mRNA:decreased expression:prostate gland

NCBI chr11:11,961,329...12,001,903
Ensembl chr11:11,973,010...12,002,128

G

bone morphogenetic protein 2

disease_progression

ISO

protein:increased expression:prostate gland

NCBI chr 2:31,349,394...31,361,227
Ensembl chr 2:31,348,808...31,360,901

G

bone morphogenetic protein 4

disease_progression

ISO

protein:increased expression:prostate

NCBI chr24:31,097,673...31,104,774
Ensembl chr24:31,097,538...31,101,225

G

caspase 6

ISO

mRNA:increased expression:prostate gland

NCBI chr 7:57,592,632...57,616,094
Ensembl chr 7:57,593,342...57,607,489

G

cyclin dependent kinase 13

ameliorates

ISO

NCBI chr21:18,551,273...18,688,889
Ensembl chr21:18,553,446...18,688,525

G

glycoprotein hormones, alpha polypeptide

ISO

mRNA:increased expression:prostate gland

NCBI chr13:11,560,543...11,578,070
Ensembl chr13:11,560,222...11,578,093

G

chitinase 3 like 1

severity

ISO

protein:increased secretion:serum (human)

NCBI chr25:26,160,993...26,169,005
Ensembl chr25:26,160,961...26,169,566

G

E2F transcription factor 5

ameliorates

ISO

NCBI chr 8:80,542,390...80,587,888
Ensembl chr 8:80,542,580...80,587,226

G

eukaryotic translation initiation factor 3 subunit H

ISO

DNA:amplification

NCBI chr 8:111,283,184...111,390,835

G

growth hormone releasing hormone

ISO

mRNA:increased expression:prostate

NCBI chr 2:26,482,734...26,493,761
Ensembl chr 2:26,487,973...26,493,499

G

histone deacetylase 2

disease_progression

ISO

protein:increased expression:prostate gland

NCBI chr13:59,873,248...59,904,542
Ensembl chr13:59,873,767...59,905,742

G

histone deacetylase 3

ISO

protein:increased expression:prostate gland

NCBI chr23:44,246,296...44,263,127

G

hydroxymethylbilane synthase

ISO

mRNA:decreased expression:tumor:in matched malignant and non-malignant sample pairs (p = 0.009)

NCBI chr 1:110,457,799...110,466,361
Ensembl chr 1:110,457,537...110,466,095

G

insulin like growth factor 1 receptor

ISO

NCBI chr29:17,212,206...17,534,036
Ensembl chr29:17,459,404...17,526,930

G

inhibin subunit alpha

ISO

DNA:hypermethylation,loss of heterozygosity:promoter,genomic region:significant hypermethylation (P<0.001) in tumors vs nonmalignant controls, LOH at 2q32-36 in 42% of cases

NCBI chr10:105,467,575...105,471,388
Ensembl chr10:105,467,963...105,471,688

G

Jun proto-oncogene, AP-1 transcription factor subunit

ISO

protein:increased activation:tumor:nuclear localization in 13/16 (81.25%) of BPH and 31/36 (86.1%) of adenocarcinomas (PCa) with significantly stronger staining in PCa (P=0.006)

NCBI chr20:74,204,481...74,207,835
Ensembl chr20:74,205,542...74,206,546

G

MET proto-oncogene, receptor tyrosine kinase

disease_progression

ISO

protein:increased expression:primary tumor, metastatic carcinoma (human)

NCBI chr21:85,370,574...85,486,405
Ensembl chr21:85,397,645...85,488,093

G

matrix Gla protein

ISO

mRNA:increased expression:primary tumor; mRNA:decreased expression:metastatic tissue:decreased or absent expression in metastases and cell lines from metastatic tumors

NCBI chr11:14,776,668...14,780,796
Ensembl chr11:14,776,209...14,780,947

G

marker of proliferation Ki-67

ISO

NCBI chr 9:120,697,183...120,727,039
Ensembl chr 9:120,698,834...120,726,866

G

matrix metallopeptidase 7

ISO

NCBI chr 1:93,889,189...93,901,077
Ensembl chr 1:93,889,198...93,899,587

G

NME/NM23 nucleoside diphosphate kinase 1

ISO

NCBI chr16:42,186,039...42,195,608
Ensembl chr16:42,185,260...42,195,616

G

platelet derived growth factor subunit B

ISO

NCBI chr19:21,865,792...21,888,068
Ensembl chr19:21,863,768...21,886,395

G

platelet derived growth factor D

disease_progression

ISO

NCBI chr 1:95,293,263...95,551,138
Ensembl chr 1:95,292,193...95,385,199

G

polo like kinase 1

ISO

mRNA, protein:increased expression:prostate gland

NCBI chr 5:21,388,957...21,408,574
Ensembl chr 5:21,396,204...21,410,718

G

protein kinase C alpha

ISO

NCBI chr16:54,638,548...55,144,372
Ensembl chr16:54,642,729...54,948,256

G

seryl-tRNA synthetase 1

ISO

mRNA:decreased expression:prostate gland (human)

NCBI chr20:24,303,741...24,321,931

G

S-phase kinase associated protein 2

ISO

NCBI chr 4:35,009,114...35,040,518
Ensembl chr 4:35,009,076...35,042,632

G

serine peptidase inhibitor, Kunitz type 1

disease_progression

ISO

protein:decreased expression:prostate gland (human)

NCBI chr26:42,136,749...42,150,125
Ensembl chr26:42,134,536...42,150,118

G

secreted phosphoprotein 1

ISO

NCBI chr 7:36,337,165...36,344,927
Ensembl chr 7:36,338,386...36,344,407

G

signal transducer and activator of transcription 3

ISO

protein:increased activity:prostate gland

PMID:11987152 PMID:18210874

RGD:2291910 RGD:2298538

NCBI chr16:63,877,884...63,957,894
Ensembl chr16:63,922,862...63,957,984

G

signal transducer and activator of transcription 6

ISO

protein:increased activity:tumor:significant increase in constitutive activation vs adjacent normal tissue and unrelated normal prostate, by EMSA

NCBI chr11:53,005,378...53,020,899
Ensembl chr11:53,006,145...53,021,203

G

transmembrane BAX inhibitor motif containing 6

ISO

mRNA:increased expression:prostate gland

NCBI chr11:45,976,689...46,001,021
Ensembl chr11:45,976,700...46,001,457

G

tumor protein p73

disease_progression

ISO

mRNA, protein:increased expression:prostate gland

NCBI chr20:127,958,002...128,035,792
Ensembl chr20:127,958,809...128,013,691

prostate carcinoma in situ

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha-methylacyl-CoA racemase

disease_progression

ISO

NCBI chr 4:33,221,777...33,244,829
Ensembl chr 4:33,225,754...33,244,836

G

angiogenin

ISO

NCBI chr29:21,215,985...21,226,927

G

apurinic/apyrimidinic endodeoxyribonuclease 1

ISO

protein:increased expression, altered localization:prostate, cytoplasm

NCBI chr29:20,978,878...20,981,393

G

androgen receptor

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr X:57,380,587...57,553,613
Ensembl chr X:57,380,611...57,546,776

G

amphiregulin

ISO

protein:increased expression:prostate gland

NCBI chr 7:22,979,574...22,990,179
Ensembl chr 7:22,980,249...22,990,162

G

ATM serine/threonine kinase

ISO

protein:increased serine phosphorylation:prostate gland

NCBI chr 1:99,653,208...99,786,889
Ensembl chr 1:99,653,139...99,791,520

G

aurora kinase A

ISO

protein:increased expression:prostate gland

PMID:15754349 PMID:16707419

RGD:2293877 RGD:2293883

NCBI chr 2:7,730,060...7,753,167
Ensembl chr 2:7,734,128...7,752,395

G

aurora kinase B

ISO

NCBI chr16:7,571,255...7,583,034
Ensembl chr16:7,570,538...7,582,959

G

BTG anti-proliferation factor 2

ISO

protein:decreased expression:prostate gland

NCBI chr25:26,032,404...26,036,500
Ensembl chr25:26,034,632...26,036,538

G

coactivator associated arginine methyltransferase 1

ISO

protein:increased expression:prostate gland

NCBI chr 6:9,866,715...9,915,655
Ensembl chr 6:9,866,534...9,914,682

G

cyclin D1

ISO

mRNA, protein:decreased expression:prostate gland

NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357

G

cyclin E1

ISO

mRNA, protein:increased expression:prostate gland

NCBI chr 6:24,879,923...24,888,985

G

cadherin 1

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 5:58,578,244...58,679,677
Ensembl chr 5:58,578,146...58,679,541

G

cyclin dependent kinase inhibitor 1B

ISO

CTD Direct Evidence: therapeutic

PMID:18691549 PMID:20932324

NCBI chr11:12,612,064...12,617,228
Ensembl chr11:12,612,079...12,617,531

G

cAMP responsive element binding protein 3 like 4

severity

ISO

NCBI chr20:9,839,137...9,848,413
Ensembl chr20:9,838,085...9,845,287

G

colony stimulating factor 1 receptor

ISO

protein:increased expression:prostate gland

NCBI chr23:52,663,290...52,723,652
Ensembl chr23:52,664,076...52,697,304

G

cytochrome P450 family 19 subfamily A member 1

ISO

NCBI chr26:32,074,260...32,164,926
Ensembl chr26:32,132,425...32,164,277

G

DNA methyltransferase 1

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 6:9,199,006...9,263,890
Ensembl chr 6:9,199,003...9,263,607

G

estrogen receptor 1

ISO

CTD Direct Evidence: marker/mechanism

PMID:16220300 PMID:22025007

NCBI chr13:79,153,418...79,554,552
Ensembl chr13:79,270,265...79,554,549

G

estrogen receptor 2

treatment

ISO

CTD Direct Evidence: marker/mechanism

PMID:16220300 PMID:22025007

NCBI chr24:41,426,333...41,513,802
Ensembl chr24:41,447,224...41,512,486

G

fibroblast growth factor 6

ISO

protein:increased expression:prostate gland

NCBI chr11:4,464,159...4,476,592
Ensembl chr11:4,464,171...4,473,916

G

fibroblast growth factor 8

ISO

NCBI chr 9:94,797,157...94,803,725
Ensembl chr 9:94,798,088...94,803,629

G

fibroblast growth factor receptor 1

ISO

NCBI chr 8:36,426,116...36,485,683
Ensembl chr 8:36,427,110...36,485,508

G

fibroblast growth factor receptor 2

ISO

NCBI chr 9:114,234,344...114,354,736
Ensembl chr 9:114,234,250...114,354,704

G

fms related receptor tyrosine kinase 1

ISO

protein:decreased expression:prostate gland

NCBI chr 3:7,412,506...7,608,122
Ensembl chr 3:7,412,172...7,607,967

G

frizzled class receptor 4

ISO

protein:increased expression:prostate gland

NCBI chr 1:78,164,243...78,199,296
Ensembl chr 1:78,188,630...78,198,187

G

glutathione S-transferase pi 1

ISO

CTD Direct Evidence: marker/mechanism

PMID:22581815 PMID:24312188

NCBI chr 1:6,676,897...6,679,936

G

histone deacetylase 1

ISO

protein:increased expression:prostate gland

NCBI chr20:100,529,782...100,575,953
Ensembl chr20:100,530,369...100,558,556

G

insulin like growth factor 1

ISO

protein:increased expression:prostate gland

NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308

G

KRAS proto-oncogene, GTPase

ISO

NCBI chr11:24,963,396...25,010,747
Ensembl chr11:24,973,619...25,005,191

G

lymphoid enhancer binding factor 1

ISO

NCBI chr 7:55,974,770...56,096,214
Ensembl chr 7:55,990,621...56,094,110

G

LDL receptor related protein 1

ISO

protein:increased expression:prostate gland

NCBI chr11:53,039,147...53,125,041
Ensembl chr11:53,039,364...53,125,776

G

mitogen-activated protein kinase kinase 4

disease_progression

ISO

protein:increased expression

NCBI chr16:11,366,610...11,485,411
Ensembl chr16:11,366,751...11,486,125

G

mitogen-activated protein kinase kinase 6

disease_progression

ISO

protein:increased expression

NCBI chr16:52,045,398...52,188,416
Ensembl chr16:52,057,784...52,187,997

G

mitogen-activated protein kinase kinase 7

disease_progression

ISO

protein:increased expression

NCBI chr 6:7,355,387...7,365,944
Ensembl chr 6:7,355,434...7,364,398

G

MYC proto-oncogene, bHLH transcription factor

ISO

NCBI chr 8:122,282,989...122,288,392
Ensembl chr 8:122,282,630...122,288,384

G

prohibitin 1

ISO

mRNA, protein:increased expression:prostate gland

NCBI chr16:69,805,968...69,816,792
Ensembl chr16:69,806,923...69,816,754

G

Pim-1 proto-oncogene, serine/threonine kinase

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr17:34,968,661...34,973,920
Ensembl chr17:34,968,429...34,973,760

G

serine protease 8

disease_progression

ISO

mRNA, protein:increased expression:prostate gland

NCBI chr 5:27,820,898...27,827,873
Ensembl chr 5:27,817,830...27,824,926

G

phosphatase and tensin homolog

ISO

CTD Direct Evidence: marker/mechanism

PMID:18268330 PMID:19081794 PMID:22581815

NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146

G

prostaglandin-endoperoxide synthase 2

ISO

protein:altered localization

NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429

G

RELA proto-oncogene, NF-kB subunit

ISO

protein:increased expression:prostate gland

PMID:15570007 PMID:16278667

RGD:2298767 RGD:2298769

NCBI chr 1:8,576,059...8,585,561
Ensembl chr 1:8,576,542...8,586,516

G

retinoid X receptor alpha

ISO

protein:decreased expression:prostate

NCBI chr12:3,704,129...3,814,707
Ensembl chr12:3,699,923...3,814,678

G

solute carrier family 30 member 4

ISO

protein:decreased expression:prostate gland

NCBI chr26:37,692,164...37,732,102
Ensembl chr26:37,692,219...37,731,292

G

SMAD family member 4

ISO

protein:increased expression:prostate gland

NCBI chr18:29,894,157...29,951,445
Ensembl chr18:29,897,621...29,934,478

G

ST14 transmembrane serine protease matriptase

ISO

protein:increased expression:prostate gland

NCBI chr 1:121,238,666...121,290,528
Ensembl chr 1:121,238,643...121,290,007

G

serine/threonine kinase 11

ISO

NCBI chr 6:973,033...996,857
Ensembl chr 6:974,144...995,136

G

TIMP metallopeptidase inhibitor 4

ISO

NCBI chr22:48,134,133...48,140,870
Ensembl chr22:48,134,637...48,140,600

G

DNA topoisomerase II beta

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr15:70,266,267...70,332,079
Ensembl chr15:70,266,601...70,332,824

G

tumor protein p63

ISO

protein:decreased expression:prostate gland
CTD Direct Evidence: marker/mechanism

PMID:17189982 PMID:17982114 PMID:22581815

RGD:2315433 RGD:2315434

NCBI chr15:83,861,489...84,126,675

prostate malignant phyllodes tumor

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

prostate-specific antigen

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 6:43,905,684...43,911,925

prostate small cell carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

BRCA2 DNA repair associated

ISO

ClinVar Annotator: match by term: Metastatic Prostate Small Cell Carcinoma

PMID:10550133 PMID:10660329 PMID:11597388 PMID:11802209 PMID:15024741 More...

NCBI chr 3:11,070,086...11,155,257
Ensembl chr 3:11,071,682...11,155,213

Term paths to the root

Path 1
Term	Annotations
disease	15628
disease of anatomical entity	15289
reproductive system disease	3089
reproductive organ cancer	1380
male reproductive organ cancer	813
prostate cancer	809
Familial Prostate Cancer +	69
Prostate Cancer, Somatic	6
Prostate Cancer/Brain Cancer Susceptibility	1
prostate carcinoma +	144
prostate lymphoma	0
prostate malignant phyllodes tumor	1
prostate neuroendocrine neoplasm	0
prostate sarcoma +	0
Path 2
Term	Annotations
disease	15628
disease of anatomical entity	15289
Urogenital Diseases	4868
reproductive system disease	3089
male reproductive system disease	1963
Male Genital Neoplasms	1299
Prostatic Neoplasms	1272
prostate cancer	809
Familial Prostate Cancer +	69
Prostate Cancer, Somatic	6
Prostate Cancer/Brain Cancer Susceptibility	1
prostate carcinoma +	144
prostate lymphoma	0
prostate malignant phyllodes tumor	1
prostate neuroendocrine neoplasm	0
prostate sarcoma +	0

paths to the root