prostate cancer - Ontology Report - Rat Genome Database

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RGD DISEASE ONTOLOGY - ANNOTATIONS

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RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:	prostate cancer	go back to main search page
Accession:	DOID:10283	browse the term
Definition:	A male reproductive organ cancer that is located_in the prostate. (DO)
Synonyms:	exact_synonym:	NGP - new growth of prostate; cancer of prostate; cancer of the prostate; malignant tumor of prostate; malignant tumor of the prostate; prostate cancers; prostatic cancer; tumor of the prostate
	narrow_synonym:	GEN1-RELATED CONDITION; GEN1-RELATED PROSTATE CANCER; PROSTATE CANCER, PROGRESSION AND METASTASIS OF; familial prostate cancer
	related_synonym:	CYP3A4 PROMOTER POLYMORPHISM, Cyp3a4-v; prostate cancer, susceptibility to; prostate cancer, susceptibility to, in African Americans
	xref:	EFO:0000196; ICD10CM:C61; ICD9CM:185; MIM:176807; MONDO:0008315; NCI:C3343; NCI:C7378; ORDO:1331
For additional species annotation, visit the Alliance of Genome Resources.

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Genes (829)

prostate cancer

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily A member 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:1,132,435...1,196,226
Ensembl chr16:2,376,006...2,437,427

G

ATP binding cassette subfamily C member 4 (PEL blood group)

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:76,193,929...76,476,119
Ensembl chr13:95,349,915...95,582,058

G

ATP binding cassette subfamily E member 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:137,445,210...137,476,309
Ensembl chr 4:149,105,912...149,137,028

G

ATP binding cassette subfamily F member 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:181,221,309...181,229,662
Ensembl chr 3:189,704,188...189,712,143

G

ATP binding cassette subfamily G member 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:113,987,709...114,001,354
Ensembl chr11:117,916,043...117,929,636

G

ankyrin repeat and BTB domain containing 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:104,888,102...105,229,573

G

acid phosphatase 3

disease_progression

ISO

PSA/PAP (prostatic acid phosphatase) ratio - a valuable prognostic indicator in men with Stage IV prostate cancer
OMIM:176807 | OMIM:300147 | OMIM:300704 | OMIM:601518 | OMIM:602759 | OMIM:608656 | OMIM:608658 | OMIM:609299 | OMIM:609558 | OMIM:610321 | OMIM:610997 | OMIM:611100 | OMIM:611868 | OMIM:611928 | OMIM:611955 | OMIM:611958 | OMIM:611959

PMID:16024648 PMID:17991541

RGD:2301054 RGD:2301055

NCBI chr 3:129,392,396...129,465,962
Ensembl chr 3:136,713,816...136,764,655

G

acrosomal vesicle protein 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:120,493,328...120,502,632
Ensembl chr11:124,406,467...124,415,043

G

acyl-CoA synthetase long chain family member 3

disease_progression
treatment

ISO

NCBI chr2B:110,100,210...110,181,277
Ensembl chr2B:228,706,142...228,759,882

G

ADAM metallopeptidase with thrombospondin type 1 motif 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:51,648,293...51,941,329
Ensembl chr 4:57,966,197...58,259,404

G

adenosine deaminase tRNA specific 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:56,162,278...56,192,856
Ensembl chr16:75,516,899...75,540,312

G

ADRM1 26S proteasome ubiquitin receptor

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:58,667,601...58,673,566
Ensembl chr20:59,985,358...59,991,668

G

adenylosuccinate lyase

severity

ISO

protein:increased activity:tumor (human)

NCBI chr22:21,249,920...21,271,749
Ensembl chr22:39,068,764...39,389,221

G

alpha fetoprotein

ISO

protein:increased expression:serum

NCBI chr 4:50,739,197...50,758,459
Ensembl chr 4:56,571,519...56,590,391

G

ArfGAP with GTPase domain, ankyrin repeat and PH domain 2

ISO

NCBI chr12:31,187,821...31,201,594

G

advanced glycosylation end-product specific receptor

ISO

mRNA:increased expression:prostate gland (human)

NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641

G

1-acylglycerol-3-phosphate O-acyltransferase 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:107,749,195...107,763,033
Ensembl chr 9:136,722,914...136,737,286

G

aryl hydrocarbon receptor repressor

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

Ensembl chr 5:436,542...567,310

G

apoptosis inducing factor mitochondria associated 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr X:119,256,425...119,292,612
Ensembl chr X:129,550,287...129,586,271

G

A-kinase anchoring protein 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:51,162,993...51,199,202
Ensembl chr17:56,023,381...56,058,744

G

aldo-keto reductase family 1 member C3

disease_progression

ISO

protein:increased expression:epithelium:
ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:24571686

NCBI chr10:5,079,580...5,157,572
Ensembl chr10:5,081,214...5,139,812

G

AKT serine/threonine kinase 1

severity

ISO

DNA:SNPs:5' utr, intron: (rs1130214, rs2494738) (human)

NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756

G

AKT serine/threonine kinase 2

ISO

DNA:SNP: :rs7254617 (human)

NCBI chr19:37,275,799...37,331,971
Ensembl chr19:45,791,800...45,840,271

G

AKT serine/threonine kinase 3

severity

ISO

DNA:SNP: :rs2125230 (human)

NCBI chr 1:219,107,482...219,463,140
Ensembl chr 1:224,480,784...224,824,838

G

aldehyde dehydrogenase 5 family member A1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:24,332,093...24,370,764
Ensembl chr 6:24,665,026...24,705,151

G

aldehyde dehydrogenase 9 family member A1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:141,094,261...141,130,613
Ensembl chr 1:144,883,839...144,919,670

G

arachidonate 12-lipoxygenase, 12S type

disease_progression

ISO

mRNA:increased expression:prostate gland

NCBI chr17:7,026,839...7,041,598
Ensembl chr17:7,014,591...7,029,602

G

adenosylmethionine decarboxylase 1

ISO

protein:increased expression:prostate

NCBI chr 6:108,678,741...108,699,695
Ensembl chr 6:112,761,072...112,782,074

G

angiogenin

ISO

PMID:11948474 PMID:19276260

RGD:2325697 RGD:2325707

NCBI chr14:1,548,693...1,558,528
Ensembl chr14:19,614,950...19,615,393

G

ankyrin repeat domain 12

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr18:5,002,212...5,153,112
Ensembl chr18:7,287,287...7,385,041

G

anoctamin 9

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:415,570...441,389
Ensembl chr11:453,054...477,950

G

annexin A7

ISO

protein:decreased expression:prostate gland

NCBI chr10:69,923,353...69,962,980
Ensembl chr10:72,381,447...72,420,749

G

adaptor related protein complex 3 subunit beta 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr 5:37,015,518...37,305,769
Ensembl chr 5:37,503,162...37,840,205

G

APC regulator of WNT signaling pathway

disease_progression

ISO

OMIM:176807 | OMIM:300147 | OMIM:300704 | OMIM:601518 | OMIM:602759 | OMIM:608656 | OMIM:608658 | OMIM:609299 | OMIM:609558 | OMIM:610321 | OMIM:610997 | OMIM:611100 | OMIM:611868 | OMIM:611928 | OMIM:611955 | OMIM:611958 | OMIM:611959

NCBI chr 5:108,070,697...108,208,273
Ensembl chr 5:113,904,352...114,009,709

G

androgen receptor

treatment
no_association

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: Prostate cancer
african-american men

PMID:1307250 PMID:1631125 PMID:1779964 PMID:2594783 PMID:7671849 More...

RGD:10043311 RGD:1578686

NCBI chr X:56,722,828...56,909,004
Ensembl chr X:66,791,081...66,969,357

G

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:137,014,286...137,042,786
Ensembl chr 5:143,127,414...143,153,318

G

Rho GTPase activating protein 20

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:105,457,931...105,593,644
Ensembl chr11:109,289,419...109,437,294

G

Rho guanine nucleotide exchange factor 15

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr17:43,336,764...43,349,787
Ensembl chr17:48,070,223...48,082,499

G

Rho guanine nucleotide exchange factor 25

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:31,309,527...31,316,648
Ensembl chr12:31,569,173...31,575,971

G

Rho guanine nucleotide exchange factor 40

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:1,884,772...1,904,120
Ensembl chr14:19,969,664...19,985,466

G

armadillo repeat containing 12

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:35,299,170...35,311,231
Ensembl chr 6:36,500,828...36,512,824

G

cAMP regulated phosphoprotein 21

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:35,558,119...35,715,157
Ensembl chr 3:35,852,051...36,008,061

G

acid sensing ion channel subunit 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:22,628,322...23,774,249

G

aspartic peptidase retroviral like 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr2A:70,008,862...70,198,244
Ensembl chr2A:71,120,541...71,121,572

G

activating transcription factor 3

disease_progression
treatment

ISO

PMID:26522727 PMID:26944919

RGD:13506816 RGD:13506817

NCBI chr 1:188,176,728...188,188,842
Ensembl chr 1:193,036,793...193,049,150

G

autophagy related 13

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:46,567,728...46,623,609
Ensembl chr11:47,126,380...47,182,850

G

atlastin GTPase 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:58,980,645...59,029,720
Ensembl chr11:62,337,788...62,380,598

G

ATM serine/threonine kinase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23807571 PMID:25614872 PMID:25741868 PMID:28492532

NCBI chr11:103,109,979...103,256,405
Ensembl chr11:106,584,228...106,727,041

G

ATPase Na+/K+ transporting subunit alpha 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:86,162,401...86,193,883
Ensembl chr 1:121,212,488...121,243,099

G

ATPase plasma membrane Ca2+ transporting 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:179,231,712...179,348,759
Ensembl chr 1:183,580,773...183,639,882

G

ATPase H+ transporting V0 subunit a1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:14,793,717...14,857,706
Ensembl chr17:15,017,695...15,082,470

G

beta-1,3-galactosyltransferase 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr2B:54,550,248...55,124,358

G

BRISC and BRCA1 A complex member 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr2A:27,884,907...28,338,302
Ensembl chr2A:27,974,917...28,420,519

G

BAG cochaperone 1

ISO

DNA, protein:amplification, increased expression:prostate gland

NCBI chr 9:33,033,267...33,043,013
Ensembl chr 9:33,841,449...33,851,167

G

BCL2 associated X, apoptosis regulator

ISO

PMID:17575222 PMID:18444130

RGD:1643354 RGD:2292907

NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468

G

BCL2 apoptosis regulator

disease_progression

ISO

PMID:16984224 PMID:17850375 PMID:18084610

RGD:2292512 RGD:2293015 RGD:2293017

NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100

G

bone gamma-carboxyglutamate protein

ISO

NCBI chr 1:131,583,789...131,586,459
Ensembl chr 1:135,413,871...135,416,432

G

BICRA like chromatin remodeling complex associated protein

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:42,338,441...42,457,989
Ensembl chr 6:43,695,491...43,756,892

G

BCL2 interacting killer

ISO

NCBI chr22:23,994,256...24,014,244
Ensembl chr22:42,207,149...42,213,022

G

baculoviral IAP repeat containing 5

severity

ISO

mRNA:increased expression:prostate gland

PMID:17804712 PMID:18336887

RGD:2293091 RGD:2293100

NCBI chr17:72,292,332...72,303,493
Ensembl chr17:77,842,724...77,854,159

G

bridge-like lipid transfer protein family member 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:28,130,426...28,161,165
Ensembl chr17:28,634,450...28,664,983

G

bone morphogenetic protein 2

disease_progression
susceptibility

ISO

DNA:amplification:prostate gland

PMID:15042598 PMID:17656261

RGD:2289030 RGD:2299981

NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610

G

bone morphogenetic protein 6

ISO

protein:increased expression:prostate

NCBI chr 6:7,564,164...7,720,341
Ensembl chr 6:7,848,249...8,000,649

G

bone morphogenetic protein 7

susceptibility

ISO

DNA:amplification:prostate gland
protein:decreased expression:prostate gland

PMID:15861517 PMID:17656261

RGD:2289030 RGD:2289031

NCBI chr20:53,509,484...53,606,889
Ensembl chr20:54,788,974...54,885,021

G

BCL2 interacting protein 5

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:35,873,854...35,888,962
Ensembl chr 6:37,077,906...37,089,299

G

BRCA1 DNA repair associated

no_association
severity

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate
DNA:deletions: :185_186del,1294_1333del,3875_3878del

PMID:10398279 PMID:12491487 PMID:15235020 PMID:15447980 PMID:16267036 More...

RGD:2289042 RGD:734657

NCBI chr17:14,197,946...14,279,064
Ensembl chr17:14,428,526...14,506,815

G

BRCA2 DNA repair associated

disease_progression

ISO

DNA:mutation
ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: Prostate cancer

RGD
ClinVar
OMIM

PMID:1 PMID:278235 PMID:1772447 PMID:2200631 PMID:2661312 More...

NCBI chr13:13,574,422...13,658,967
Ensembl chr13:32,010,066...32,091,332

G

BRF2 general transcription factor IIIB subunit

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:25741868

NCBI chr 8:37,144,341...37,150,371
Ensembl chr 8:34,321,746...34,327,622

G

BTB domain containing 16

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:118,842,396...118,907,233
Ensembl chr10:122,259,648...122,318,423

G

C2 calcium dependent domain containing 6

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr2B:88,742,121...88,873,268

G

complement C3a receptor 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:8,178,064...8,186,206
Ensembl chr12:8,220,933...8,222,381

G

complement C5

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:92,069,574...92,202,513
Ensembl chr 9:120,426,354...120,523,856

G

calcineurin binding protein 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr22:4,816,411...4,984,760
Ensembl chr22:22,927,572...23,070,165

G

calcium voltage-gated channel subunit alpha1 D

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:53,432,189...53,751,347
Ensembl chr 3:54,495,952...54,970,444

G

cell adhesion molecule 1

ISO

DNA:hypermethylation:promoter

NCBI chr11:110,008,314...110,347,876
Ensembl chr11:113,950,291...114,280,324

G

cell adhesion molecule 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:134,522,614...134,552,959
Ensembl chr 1:138,319,952...138,350,307

G

calcium dependent secretion activator

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:62,321,496...62,797,298

G

calcium/calmodulin dependent protein kinase II inhibitor 1

disease_progression

ISO

mRNA, protein:decreased expression:prostate gland

PMID:25003983 PMID:31762801

RGD:18337271 RGD:18337280

NCBI chr 1:19,437,761...19,441,573
Ensembl chr 1:20,479,562...20,482,600

G

cullin associated and neddylation dissociated 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:21,592,833...21,638,382
Ensembl chr12:22,099,962...22,145,013

G

calpain 6

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:100,363,233...100,388,631
Ensembl chr X:110,822,170...110,848,000

G

calcium/calmodulin dependent serine protein kinase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:33,967,329...34,374,385
Ensembl chr X:41,659,295...42,066,570

G

caspase 1

ISO

protein:decreased expression:prostate gland

NCBI chr11:99,965,964...99,975,640
Ensembl chr11:103,448,497...103,458,149
Ensembl chr11:103,448,497...103,458,149

G

caspase 3

ISO

NCBI chr 4:176,793,190...176,815,023
Ensembl chr 4:189,018,422...189,040,185

G

calcium sensing receptor

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:119,278,071...119,383,901
Ensembl chr 3:126,252,765...126,285,268

G

caveolin 1

disease_progression

ISO

protein:increased expression:serum
DNA:hypermethylation:promoter

PMID:11170154 PMID:14506154 PMID:15948133

RGD:2289104 RGD:2289109 RGD:2289112

NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655

G

chromobox 1

ISO

protein:increased expression:prostate:

NCBI chr17:9,434,141...9,467,865

G

chromobox 3

ISO

protein:increased expression:prostate:

NCBI chr 7:26,847,247...26,859,339
Ensembl chr 7:26,450,411...26,462,350

G

chromobox 5

ISO

protein:increased expression:prostate:

NCBI chr12:34,463,826...34,521,656
Ensembl chr12:35,218,239...35,236,009

G

chromobox 7

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr22:20,037,529...20,059,459
Ensembl chr22:37,854,056...37,876,084

G

chibby 1, beta catenin antagonist

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr22:19,571,658...19,588,872
Ensembl chr22:37,389,948...37,406,879

G

coiled-coil domain containing 171

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:15,369,104...15,788,076
Ensembl chr 9:15,883,639...16,289,668

G

cyclin A1

disease_progression

ISO

human gene, mouse model

NCBI chr13:17,649,064...17,660,550
Ensembl chr13:36,080,331...36,092,078

G

cyclin B1

ISO

NCBI chr 5:44,826,103...44,836,832
Ensembl chr 5:46,394,362...46,405,332

G

cyclin D1

ISO

NCBI chr11:64,737,006...64,750,353

G

cyclin D2

disease_progression

ISO

DNA, mRNA:hyperymethylation, decreased expression:promoter, prostate gland

PMID:16322291 PMID:17016690

RGD:151665170 RGD:2289151

NCBI chr12:4,385,957...4,417,602
Ensembl chr12:4,309,272...4,335,551

G

cyclin D3

disease_progression

ISO

NCBI chr 6:41,518,421...41,630,103
Ensembl chr 6:42,820,569...42,827,498

G

CD2 molecule

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:85,752,522...85,767,323
Ensembl chr 1:120,749,918...120,764,659

G

CD244 molecule

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:136,186,906...136,219,669
Ensembl chr 1:140,110,808...140,123,065

G

CD2 associated protein

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:47,065,284...47,210,746
Ensembl chr 6:48,328,863...48,474,163

G

CD44 molecule (IN blood group)

disease_progression

ISO

DNA:hypermethylation:prostate gland

NCBI chr11:35,110,732...35,258,238
Ensembl chr11:34,985,634...35,079,009

G

CD55 molecule (Cromer blood group)

ISO

PMID:16533428 PMID:18288643

RGD:2326167 RGD:2326168

NCBI chr 1:182,923,369...182,962,518
Ensembl chr 1:187,201,081...187,240,350

G

CD82 molecule

disease_progression

ISO

protein:decreased expression:prostate gland

NCBI chr11:44,526,010...44,581,560
Ensembl chr11:45,020,319...45,075,876

G

cell division cycle 25A

ISO

NCBI chr 3:48,068,601...48,099,806
Ensembl chr 3:49,154,307...49,186,115

G

cell division cycle 25B

ISO

protein:increased expression:prostate gland

NCBI chr20:3,877,255...3,883,458
Ensembl chr20:3,626,107...3,645,179

G

cell division cycle 25C

ISO

mRNA, protein:alternative form, increased expression, increased activity:prostate gland

PMID:12896904 PMID:16000564 PMID:16140946 PMID:17460776

RGD:2756028 RGD:2774210 RGD:2776427 RGD:4105453

NCBI chr 5:133,663,210...133,717,974
Ensembl chr 5:139,795,565...139,842,698

G

cadherin 1

disease_progression
susceptibility

ISO

protein:decreased expression:prostate gland
ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: PROSTATE CANCER, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Prostate cancer
DNA:polymorphism:promoter:-160C>A (human)

PMID:1722187 PMID:2403327 PMID:2449335 PMID:8075649 PMID:9537325 More...

RGD:2289487 RGD:2289493

NCBI chr16:49,108,745...49,206,347
Ensembl chr16:68,502,584...68,596,488

G

cadherin 13

disease_progression

ISO

DNA:hypermethylation:promoter

NCBI chr16:63,255,482...64,418,053
Ensembl chr16:82,883,184...83,808,996

G

cadherin 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr16:49,015,115...49,071,903
Ensembl chr16:68,407,625...68,465,287

G

cyclin dependent kinase 13

ISO

mRNA,protein:increased expression:prostate:

NCBI chr 7:44,138,345...44,285,606
Ensembl chr 7:44,177,204...44,324,683

G

cyclin dependent kinase 2

ISO

NCBI chr12:32,940,225...32,946,236
Ensembl chr12:33,189,934...33,195,945

G

cyclin dependent kinase 4

ISO

NCBI chr12:31,174,446...31,178,597
Ensembl chr12:31,434,594...31,438,876

G

cyclin dependent kinase inhibitor 1A

ISO

NCBI chr 6:36,241,405...36,250,032
Ensembl chr 6:37,436,990...37,445,599

G

cyclin dependent kinase inhibitor 2A

disease_progression

ISO

protein:increased expression:prostate gland
DNA:hypermethylation:promoter

PMID:16483154 PMID:16799475

RGD:2289684 RGD:2289685

NCBI chr 9:21,803,862...21,831,322

G

CDKN2A interacting protein

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:175,621,561...175,626,138
Ensembl chr 4:187,848,215...187,852,673

G

cyclin dependent kinase inhibitor 2B

disease_progression

ISO

protein:increased expression:prostate gland

NCBI chr 9:21,838,902...21,845,355
Ensembl chr 9:22,455,662...22,462,156

G

ceramide synthase 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:79,128,338...79,272,018
Ensembl chr15:98,422,256...98,521,775

G

cilia and flagella associated protein 43

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:100,729,982...100,831,694
Ensembl chr10:104,188,653...104,290,557

G

cilia and flagella associated protein 65

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr2B:106,260,872...106,299,594
Ensembl chr2B:224,854,262...224,892,490

G

ChaC glutathione specific gamma-glutamylcyclotransferase 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:19,895,554...19,898,672
Ensembl chr15:38,145,730...38,148,698

G

chromatin assembly factor 1 subunit B

disease_progression

ISO

protein:increased expression:prostate:
ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:19309489 PMID:23265383

NCBI chr21:22,755,721...22,786,958
Ensembl chr21:36,113,971...36,143,575

G

chromodomain helicase DNA binding protein 1

ISO

DNA:deletions: :

NCBI chr 5:94,165,414...94,238,836
Ensembl chr 5:99,721,032...99,790,263

G

chromodomain helicase DNA binding protein 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:71,568,560...71,713,330
Ensembl chr15:90,781,169...90,903,569

G

checkpoint kinase 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:120,446,352...120,478,207
Ensembl chr11:124,359,218...124,390,981

G

checkpoint kinase 2

susceptibility

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: Prostate cancer | ClinVar Annotator: match by term: Prostate cancer, susceptibility to
DNA:mutations: :multiple

OMIM
ClinVar
RGD

PMID:3313277 PMID:9536098 PMID:10617473 PMID:11053450 PMID:11298456 More...

NCBI chr22:9,757,038...9,811,171

G

chromogranin A

susceptibility

ISO

DNA:missense mutation:cds:p.E264D (human)

NCBI chr14:73,555,834...73,568,547
Ensembl chr14:92,895,450...92,908,159

G

chromogranin B

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:5,905,854...5,919,758
Ensembl chr20:5,688,837...5,859,738

G

cysteine rich hydrophobic domain 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:62,809,942...62,923,345
Ensembl chr X:72,932,415...73,040,911

G

component of inhibitor of nuclear factor kappa B kinase complex

ISO

protein:increased serine phosphorylation:prostate gland

NCBI chr10:96,794,228...96,835,449
Ensembl chr10:100,280,490...100,316,918

G

cytoskeleton associated protein 5

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:46,694,967...46,797,500
Ensembl chr11:47,252,752...47,329,274

G

CLPTM1 like

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

Ensembl chr 5:1,361,571...1,388,415

G

cyclic nucleotide gated channel subunit alpha 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:74,196,877...74,213,563
Ensembl chr 4:84,910,653...84,945,248

G

ciliary neurotrophic factor receptor

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:34,387,929...34,426,907
Ensembl chr 9:35,197,474...35,214,977

G

component of oligomeric golgi complex 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:67,120,989...67,136,480
Ensembl chr17:72,576,526...72,591,953

G

collagen type I alpha 1 chain

ISO

ClinVar Annotator: match by term: Prostate cancer

PMID:17211858 PMID:23265383 PMID:25741868 PMID:28492532

NCBI chr17:44,274,349...44,291,764
Ensembl chr17:49,150,677...49,166,677

G

collagen type XXIV alpha 1 chain

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:118,289,852...118,694,258
Ensembl chr 1:87,150,219...87,547,919

G

collagen type V alpha 1 chain

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:105,746,388...105,956,280
Ensembl chr 9:134,342,955...134,544,651

G

catechol-O-methyltransferase

no_association
disease_progression
susceptibility

ISO

DNA:polymorphism: :p.V158M
DNA:polymorphism:cds

PMID:16126332 PMID:16492910 PMID:17507624

RGD:2289718 RGD:2289719 RGD:2289720

NCBI chr22:2,704,015...2,731,326
Ensembl chr22:18,375,434...18,402,387

G

COP9 signalosome subunit 6

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:92,124,166...92,127,165
Ensembl chr 7:105,557,778...105,560,998

G

corin, serine peptidase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:74,311,036...74,555,742
Ensembl chr 4:85,043,182...85,286,573

G

carboxypeptidase A6

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:63,962,991...64,285,840
Ensembl chr 8:65,624,306...65,946,848

G

cleavage and polyadenylation specific factor 7

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:56,702,510...56,729,316
Ensembl chr11:60,065,832...60,092,720

G

CREB regulated transcription coactivator 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:69,217,679...69,333,897
Ensembl chr15:88,427,468...88,533,593

G

cone-rod homeobox

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:44,828,119...44,856,284

G

CUB and Sushi multiple domains 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:32,800,267...33,443,599
Ensembl chr 1:33,989,876...34,625,977

G

catenin alpha 1

disease_progression

ISO

protein:decreased expression:prostate gland

PMID:16334164 PMID:17639504

RGD:2289791 RGD:2289793

NCBI chr 5:134,134,944...134,313,239
Ensembl chr 5:140,261,883...140,438,547

G

catenin beta 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:9927029 PMID:23265383

NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030

G

cathepsin E

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:181,617,421...181,632,260
Ensembl chr 1:185,900,746...185,915,519

G

cortactin binding protein 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:109,675,275...109,837,178
Ensembl chr 7:122,370,616...122,520,397

G

C-X-C motif chemokine ligand 12

ameliorates

ISO

human cells in mouse model

NCBI chr10:41,296,975...41,384,864
Ensembl chr10:44,552,480...44,564,231

G

C-X-C motif chemokine receptor 4

ameliorates

ISO

human cells in mouse model

NCBI chr2B:23,744,271...23,748,106
Ensembl chr2B:140,181,829...140,189,647

G

cytochrome P450 family 17 subfamily A member 1

ISO

NCBI chr10:99,431,762...99,439,619
Ensembl chr10:102,896,376...102,901,514

G

cytochrome P450 family 1 subfamily A member 1

ISO

NCBI chr15:53,664,968...53,672,277
Ensembl chr15:73,284,566...73,290,636

G

cysteinyl leukotriene receptor 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:67,412,410...67,469,366
Ensembl chr X:77,524,455...77,525,468

G

DAB2 interacting protein

treatment

ISO

human cells in mouse model

NCBI chr 9:92,696,798...92,912,425
Ensembl chr 9:121,143,457...121,254,336

G

death domain associated protein

disease_progression

ISO

NCBI chr 6:32,890,846...32,895,307
Ensembl chr 6:34,004,543...34,008,717

G

dachsous cadherin-related 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:146,597,168...146,858,314

G

DExD-box helicase 50

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:65,367,689...65,414,023
Ensembl chr10:67,902,219...67,948,207

G

DExD/H-box helicase 60

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:160,376,930...160,532,561

G

DExD/H-box 60 like

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:160,564,376...160,687,650
Ensembl chr 4:172,643,134...172,757,278

G

DEAF1 transcription factor

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr11:652,337...709,854

G

diacylglycerol O-acyltransferase 2 like 6

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:59,445,558...59,473,714
Ensembl chr X:69,504,786...69,532,813

G

DiGeorge syndrome critical region gene 6 like

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

G

dihydrodiol dehydrogenase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:45,934,740...45,946,051
Ensembl chr19:54,810,354...54,821,618

G

DExH-box helicase 29

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:58,722,594...58,773,708
Ensembl chr 5:60,345,282...60,396,244

G

DIS3 like exosome 3'-5' exoribonuclease

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:45,246,867...45,287,521
Ensembl chr15:63,523,512...63,563,813

G

dihydrolipoamide S-acetyltransferase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:106,910,857...106,950,851
Ensembl chr11:110,756,001...110,792,795

G

delta like canonical Notch ligand 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:168,440,192...168,449,071
Ensembl chr 6:173,534,292...173,544,759

G

dynein axonemal heavy chain 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:17,258,456...17,476,027
Ensembl chr16:20,964,186...21,188,542

G

dynein axonemal heavy chain 8

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:38,275,243...38,620,278
Ensembl chr 6:39,479,294...39,800,107

G

dynein axonemal heavy chain 9

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:39,673,338...40,047,090
Ensembl chr17:44,422,928...44,796,983

G

DnaJ heat shock protein family (Hsp40) member C3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:25466870 PMID:28940199

NCBI chr13:76,853,053...76,963,530
Ensembl chr13:96,033,605...96,114,165

G

DnaJ heat shock protein family (Hsp40) member C6

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:22563501 PMID:23211418 PMID:26528954 PMID:28492532

NCBI chr 1:64,501,805...64,662,999
Ensembl chr 1:66,399,968...66,550,879

G

DNA methyltransferase 1

disease_progression

ISO

protein:increased expression:nucleus:

NCBI chr19:9,681,847...9,745,334
Ensembl chr19:10,342,478...10,406,972

G

dedicator of cytokinesis 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:165,000,368...165,447,148
Ensembl chr 5:171,778,952...172,206,238

G

dedicator of cytokinesis 5

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:24,463,582...24,696,736
Ensembl chr 8:21,372,756...21,605,877

G

diphthamide biosynthesis 7

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:108,635,082...108,680,315
Ensembl chr 9:137,597,639...137,627,279

G

developmental pluripotency associated 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:106,452,105...106,463,295
Ensembl chr 3:113,380,836...113,390,400

G

dihydropyrimidine dehydrogenase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:99,736,145...100,576,663
Ensembl chr 1:98,457,934...99,300,100

G

DS cell adhesion molecule like 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:112,263,509...112,632,332
Ensembl chr11:116,196,677...116,302,262

G

dual specificity phosphatase 1

disease_progression

ISO

NCBI chr 5:168,121,536...168,124,671
Ensembl chr 5:175,032,803...175,035,960

G

dymeclin

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr18:42,427,493...42,842,450
Ensembl chr18:45,783,379...46,162,835

G

E2F transcription factor 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:29,963,083...29,973,860
Ensembl chr20:31,103,764...31,110,604

G

E2F transcription factor 3

disease_progression

ISO

PMID:15184867 PMID:17701752 PMID:25017995

RGD:13504717 RGD:13504729 RGD:13504730

NCBI chr 6:20,225,471...20,317,199
Ensembl chr 6:20,574,898...20,665,785

G

E2F transcription factor 5

ISO

mRNA,protein:increased expression:prostate:

NCBI chr 8:81,703,423...81,739,827
Ensembl chr 8:83,314,176...83,350,220

G

ELL associated factor 2

ISO

protein:decreased expression:prostate gland

NCBI chr 3:118,936,685...118,996,051
Ensembl chr 3:125,844,338...125,895,416

G

eukaryotic translation elongation factor 2

ISO

protein:increased expression:prostate (human)

NCBI chr19:3,000,608...3,009,918
Ensembl chr19:3,950,772...3,960,172

G

EF-hand calcium binding domain 6

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr22:24,414,362...24,700,901
Ensembl chr22:42,608,067...42,893,414

G

epidermal growth factor receptor

ISO

NCBI chr 7:55,614,042...55,807,285
Ensembl chr 7:56,046,296...56,111,615

G

eukaryotic translation initiation factor 3 subunit H

disease_progression

ISO

mRNA:increased expression:prostate gland
DNA:amplification

PMID:10362802 PMID:11733359

RGD:2289901 RGD:2289902

NCBI chr 8:113,320,059...113,440,769
Ensembl chr 8:115,863,490...115,973,872

G

eukaryotic translation initiation factor 4 gamma 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:19,755,217...20,123,490
Ensembl chr 1:20,800,597...21,165,755

G

elongin A2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr18:40,418,709...40,422,812

G

elastin microfibril interfacer 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr2A:27,077,551...27,085,437
Ensembl chr2A:27,166,747...27,174,525

G

endoglin

severity

ISO

protein:increased expression:tumor, vasculature (human)

NCBI chr 9:98,934,080...98,973,862
Ensembl chr 9:127,605,608...127,644,641

G

enolase 2

ISO

NCBI chr12:7,043,807...7,053,178
Ensembl chr12:6,958,960...6,968,342

G

ecto-NOX disulfide-thiol exchanger 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:24,377,918...24,722,036

G

ectonucleotide pyrophosphatase/phosphodiesterase 7

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:73,811,249...73,822,719
Ensembl chr17:79,347,505...79,359,349

G

ectonucleoside triphosphate diphosphohydrolase 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:40,290,586...40,333,632
Ensembl chr 3:40,561,694...40,604,181

G

endosomal transmembrane epsin interactor 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:55,400,544...55,468,662

G

E1A binding protein p300

disease_progression

ISO

NCBI chr22:21,986,467...22,076,921
Ensembl chr22:40,079,503...40,168,604

G

EPH receptor B1

susceptibility

ISO

DNA:SNPs,haplptype:multiple

NCBI chr 3:131,841,459...132,309,082
Ensembl chr 3:139,313,387...139,776,802

G

epithelial stromal interaction 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:24,058,760...24,162,261

G

erb-b2 receptor tyrosine kinase 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:17,560,337...17,600,808
Ensembl chr17:17,777,434...17,805,862

G

erb-b2 receptor tyrosine kinase 3

disease_progression

ISO

protein:altered localization:nucleus
ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:17532856 PMID:23265383

NCBI chr12:32,811,533...32,834,958
Ensembl chr12:33,063,434...33,084,994

G

erb-b2 receptor tyrosine kinase 4

ISO

protein:increased expression:prostate gland

NCBI chr2B:98,625,630...99,795,371
Ensembl chr2B:217,069,644...218,272,006

G

erbb2 interacting protein

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:47,929,305...48,081,381
Ensembl chr 5:49,589,418...49,676,689

G

ERCC excision repair 2, TFIIH core complex helicase subunit

susceptibility

ISO

DNA:missense mutation:cds:p.D312N (human)
DNA:polymorphism:exon:p.R156R(human)

PMID:17695467 PMID:24649009

RGD:5688739 RGD:8657136

NCBI chr19:42,298,927...42,319,816
Ensembl chr19:50,897,004...50,915,819

G

estrogen receptor 1

susceptibility
severity
disease_progression

ISO

DNA:repeat
DNA:hypermethylation:promoter
mRNA:increased expression:prostate gland

PMID:17908481 PMID:17922863 PMID:18006911

RGD:2290020 RGD:2290022 RGD:2290023

NCBI chr 6:149,507,599...149,918,523
Ensembl chr 6:154,317,002...154,631,551

G

estrogen receptor 2

susceptibility

ISO

DNA:snps, haplotype:multiple (human)

NCBI chr14:44,807,875...44,919,780
Ensembl chr14:63,064,402...63,131,303

G

exocyst complex component 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:25741868

NCBI chr 6:299,500...504,029
Ensembl chr 6:435,538...583,027

G

EYA transcriptional coactivator and phosphatase 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:67,728,057...68,060,069
Ensembl chr 8:69,387,769...69,551,829

G

enhancer of zeste 2 polycomb repressive complex 2 subunit

severity

ISO

protein:increased expression:prostate gland (human)

NCBI chr 7:140,536,962...140,613,104
Ensembl chr 7:153,017,590...153,059,726

G

coagulation factor II, thrombin

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157

G

coagulation factor V

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:144,996,757...145,070,046
Ensembl chr 1:148,718,897...148,790,915

G

fatty acid binding protein 5

ISO

mRNA:increased expression:prostate (human)

NCBI chr 8:77,803,369...77,807,630
Ensembl chr 8:79,426,684...79,430,879

G

family with sequence similarity 13 member C

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:55,781,367...55,899,161
Ensembl chr10:57,999,029...58,115,863

G

family with sequence similarity 83 member C

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:31,615,066...31,621,860
Ensembl chr20:32,737,883...32,744,579

G

FA complementation group A

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:10094191 PMID:24728327 PMID:25741868 PMID:26181256 PMID:28492532 More...

NCBI chr16:70,495,310...70,579,275
Ensembl chr16:90,163,950...90,245,147

G

Fas cell surface death receptor

disease_progression
severity

ISO

DNA:polymorphism

PMID:17667965 PMID:18237448

RGD:2289639 RGD:2290050

NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612

G

failed axon connections homolog, metaxin like GST domain containing

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:97,113,378...97,190,850
Ensembl chr 6:101,004,265...101,072,924

G

F-box DNA helicase 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:5,931,389...5,978,844
Ensembl chr10:5,915,713...5,962,778

G

fibrillin 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:123,673,209...123,953,741
Ensembl chr 5:129,435,248...129,715,711

G

F-box and leucine rich repeat protein 5

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:10,050,909...10,107,573
Ensembl chr 4:15,348,977...15,430,631

G

FYVE, RhoGEF and PH domain containing 1

ISO

protein:increased expression:prostate gland (human)

NCBI chr X:46,648,765...46,699,444
Ensembl chr X:54,880,513...54,930,672

G

FYVE, RhoGEF and PH domain containing 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:36,566,942...36,591,044
Ensembl chr 6:37,762,809...37,785,291

G

fibroblast growth factor 7

ISO

mRNA:increased expression:prostate gland stroma, hormone insensitive tumors

NCBI chr15:28,378,339...28,442,800
Ensembl chr15:46,702,119...46,770,163

G

fibroblast growth factor receptor 1

disease_progression

ISO

NCBI chr 8:37,713,133...37,773,098
Ensembl chr 8:34,890,147...34,948,904

G

fibroblast growth factor receptor 2

no_association
disease_progression

ISO

mRNA:increased expression:prostate gland
DNA:mutation,polymorphism:exons:no mutations or polymorphisms found in patient or cell line DNA to explain changes in expression seen in other studies
mRNA:splice variant::shift from Fgfr2IIIb to Fgfr2IIIc in malignancy, restoration of Fgfr2IIIb slows growth
mRNA:alternative form:prostate:switch from isoform IIIb to IIIc
mRNA:decreased expression:prostate:isoforms IIIb and IIIc, decrease in IIIb associated with progression to androgen-independence

PMID:9285567 PMID:9537256 PMID:11069376 PMID:11170144 PMID:12111699

RGD:2289086 RGD:2289728 RGD:2289746 RGD:2289845 RGD:2289859

NCBI chr10:118,055,854...118,175,440
Ensembl chr10:121,469,735...121,588,815

G

fibroblast growth factor receptor 4

disease_progression

ISO

DNA:SNP:exon 9: 288G>A, p.G388R (human)

NCBI chr 5:172,386,443...172,400,271
Ensembl chr 5:179,454,995...179,467,605

G

FHF complex subunit HOOK interacting protein 1B

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:6,345,227...6,368,675
Ensembl chr11:6,027,300...6,050,850

G

fragile histidine triad diadenosine triphosphatase

ISO

DNA:hypermethylation:promoter:methylation percentage 15% in tumors vs no methylation in nonmalignant prostate
DNA:SNP:intron:increased risk in carriers of minor allele of SNP rs760317
DNA:SNP:intron:reduced risk in carriers of minor allele of SNP rs760317

PMID:11839671 PMID:15705877 PMID:17548701

RGD:2289869 RGD:2289878 RGD:2289896

NCBI chr 3:59,670,777...61,177,974

G

fms related receptor tyrosine kinase 3

ISO

NCBI chr13:9,283,747...9,381,553
Ensembl chr13:27,627,178...27,723,940

G

forkhead box O1

disease_progression

ISO

mRNA:decreased expression:tumor:lower in high versus low Gleason score tumors, also lower in tumor vs adjacent normal tissue (p<0.05 compared to at least one housekeeping gene)

NCBI chr13:21,763,729...21,874,279

G

forkhead box O3

ISO

mRNA:decreased expression:tumor:lower in tumor vs adjacent normal tissue (p<0.05 compared to at least one housekeeping gene)

NCBI chr 6:106,360,519...106,485,676
Ensembl chr 6:110,406,266...110,516,272

G

formyl peptide receptor 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:48,689,984...48,696,121
Ensembl chr19:57,569,506...57,570,558

G

FRAS1 related extracellular matrix 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:19,900,324...20,103,303
Ensembl chr13:38,490,750...38,687,048

G

gamma-aminobutyric acid type A receptor subunit beta2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:25741868 PMID:28492532

NCBI chr 5:156,678,750...156,937,614
Ensembl chr 5:163,374,346...163,632,301

G

gamma-aminobutyric acid type A receptor subunit gamma1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:76,034,539...76,121,797
Ensembl chr 4:86,762,417...86,850,033

G

glyceraldehyde-3-phosphate dehydrogenase, spermatogenic

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:32,479,559...32,491,959
Ensembl chr19:41,216,758...41,228,750

G

growth differentiation factor 10

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:46,498,600...46,511,933

G

GEN1 Holliday junction 5' flap endonuclease

ISO

ClinVar Annotator: match by term: GEN1-related condition | ClinVar Annotator: match by term: GEN1-related prostate cancer

PMID:25741868 PMID:28492532

NCBI chr2A:17,735,953...17,766,018
Ensembl chr2A:17,862,070...17,892,048

G

guided entry of tail-anchored proteins factor 3, ATPase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:12,299,706...12,310,923
Ensembl chr19:13,045,570...13,055,908

G

GDNF family receptor alpha 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:133,630,274...133,652,525
Ensembl chr 5:139,762,690...139,784,942

G

GLI family zinc finger 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:31,453,759...31,466,194
Ensembl chr12:31,710,057...31,722,473

G

G protein subunit gamma transducin 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:85,839,639...85,859,844
Ensembl chr 7:99,446,623...99,451,185

G

glyceronephosphate O-acyltransferase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:206,794,245...206,830,840
Ensembl chr 1:211,819,259...211,855,885

G

golgi membrane protein 1

ISO

protein,mRNA:increased expression:prostate

NCBI chr 9:38,823,820...38,910,984
Ensembl chr 9:83,005,832...83,080,202

G

gephyrin

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:47,081,527...47,755,182
Ensembl chr14:66,137,166...66,634,550

G

G protein-coupled receptor 26

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:120,223,603...120,252,108

G

G protein-coupled receptor 55

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr2B:118,159,511...118,163,334
Ensembl chr2B:236,958,210...236,959,169

G

G protein-coupled receptor 82

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:34,172,153...34,176,193
Ensembl chr X:41,868,163...41,869,172

G

growth factor receptor bound protein 2

treatment
disease_progression

ISO

DNA:amplification, mutation

PMID:17372910 PMID:28930697

RGD:13504750 RGD:13504751

NCBI chr17:69,265,307...69,352,835
Ensembl chr17:74,817,471...74,903,796

G

glutamate ionotropic receptor delta type subunit 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:82,017,436...82,795,410
Ensembl chr10:85,586,147...86,353,410

G

glutamate ionotropic receptor NMDA type subunit 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:108,198,350...108,228,887
Ensembl chr 9:137,168,722...137,197,382

G

glutamate metabotropic receptor 8

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:118,430,086...119,249,147

G

gastrin releasing peptide

ISO

protein:increased expression:serum (human)

NCBI chr18:52,614,169...52,626,427
Ensembl chr18:55,942,263...55,953,188

G

glutamate rich WD repeat containing 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:45,447,004...45,455,976

G

glutathione S-transferase mu 1

ISO

Ensembl chr 1:127,979,238...128,010,411

G

glutathione S-transferase pi 1

susceptibility

ISO

DNA:polymorphism:exon:p.I105V (human)

PMID:9111193 PMID:17067754

RGD:4142515 RGD:6906883

NCBI chr11:62,942,756...62,945,701
Ensembl chr11:66,253,421...66,256,472

G

glucuronidase beta

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:60,087,130...60,109,289
Ensembl chr 7:64,724,841...64,744,909

G

heme binding protein 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:136,159,762...136,171,063

G

HEPACAM family member 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:85,145,026...85,183,278

G

HHIP like 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:80,229,854...80,304,418

G

hypoxia inducible factor 1 subunit alpha

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885

G

homeodomain interacting protein kinase 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:37,427,496...37,439,259

G

HLF transcription factor, PAR bZIP family member

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:49,353,790...49,413,676
Ensembl chr17:54,218,399...54,278,044

G

hemicentin 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:161,254,948...161,717,526
Ensembl chr 1:165,522,384...165,869,148

G

heterogeneous nuclear ribonucleoprotein K

ISO

protein:increased expression:prostate gland (human)

NCBI chr 9:40,898,593...40,911,159
Ensembl chr 9:83,324,238...83,336,756

G

homeobox B13

ISO

ClinVar Annotator: match by term: PROSTATE CANCER, SUSCEPTIBILITY TO

PMID:8756292 PMID:15964834 PMID:17138648 PMID:22236224 PMID:22714738 More...

NCBI chr17:8,807,988...8,810,362
Ensembl chr17:8,994,224...8,996,598

G

HPS3 biogenesis of lysosomal organelles complex 2 subunit 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:146,147,140...146,190,793
Ensembl chr 3:153,725,008...153,769,060

G

5-hydroxytryptamine receptor 2C

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:103,673,172...103,999,133
Ensembl chr X:114,199,485...114,503,201

G

5-hydroxytryptamine receptor 5A

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:146,672,908...146,690,001
Ensembl chr 7:158,399,874...158,416,922

G

HtrA serine peptidase 2

ISO

mRNA, protein:increased expression:prostate (human)

NCBI chr2A:74,596,020...74,599,790
Ensembl chr2A:76,102,240...76,106,152

G

inhibitor of Bruton tyrosine kinase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:80,061,649...80,139,393
Ensembl chr 6:83,325,428...83,402,670

G

intercellular adhesion molecule 1

ISO

NCBI chr19:9,821,402...9,837,021
Ensembl chr19:10,484,414...10,500,605

G

interferon induced with helicase C domain 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr2B:49,560,620...49,612,086
Ensembl chr2B:166,928,994...166,980,170

G

intraflagellar transport 43

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:56,544,333...56,642,312
Ensembl chr14:75,387,742...75,485,506

G

insulin like growth factor 1 receptor

disease_progression

ISO

NCBI chr15:77,332,926...77,648,474
Ensembl chr15:96,535,164...96,832,974

G

insulin like growth factor 2 receptor

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:157,852,565...157,990,049
Ensembl chr 6:162,878,661...162,997,762

G

insulin like growth factor binding protein 3

severity
no_association

ISO

DNA:SNP:promoter:rs2854744 C allele associated with low grade tumors only, odds ratio=4.1 for low grade vs 1.0 for high grade
DNA:SNP:promoter:rs2854744, homozygous C allele associated with 2x increased risk
DNA:SNP:promoter:no association with rs2854744, 440 cases and 480 related controls from Cleveland, OH and Detroit, MI

PMID:15006930 PMID:17668637 PMID:17724372

RGD:2290008 RGD:2290012 RGD:2290015

NCBI chr 7:46,564,234...46,573,145

G

inhibitor of nuclear factor kappa B kinase subunit beta

ISO

protein:increased serine phosphorylation:prostate gland

NCBI chr 8:41,515,613...41,576,229
Ensembl chr 8:38,960,594...39,020,971

G

interleukin 16

ISO

DNA:SNP:exon:rs4072111 (human)

NCBI chr15:60,181,827...60,299,406
Ensembl chr15:79,122,988...79,250,861

G

interleukin 33

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:6,027,014...6,069,540
Ensembl chr 9:6,234,178...6,248,624

G

integrin linked kinase

disease_progression

ISO

mRNA:decreased expression:tumor:lower in high versus low Gleason score tumors (p<0.05 compared to at least one housekeeping gene)
protein:decreased expression:tumor:significantly lower in benign prostatic hyperplasia then any prostate cancer (p<0.01), gradient of expression from BPH to poorly differentiated C+D stage neoplasms

PMID:15704679 PMID:18336616

RGD:2301729 RGD:2301731

NCBI chr11:6,735,735...6,742,922
Ensembl chr11:6,418,717...6,425,788

G

interphotoreceptor matrix proteoglycan 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:25741868

NCBI chr 3:98,325,379...98,418,344
Ensembl chr 3:105,005,553...105,097,902

G

inhibitor of growth family member 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:6,782,402...6,795,035
Ensembl chr12:6,698,843...6,710,955

G

inhibin subunit alpha

ISO

mRNA,protein:decreased expression:malignant tumors

NCBI chr2B:106,828,948...106,832,993
Ensembl chr2B:225,419,176...225,423,386

G

indolethylamine N-methyltransferase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:31,359,126...31,369,757
Ensembl chr 7:31,485,671...31,489,661

G

insulin

disease_progression

ISO

NCBI chr11:2,200,785...2,202,579
Ensembl chr11:2,218,117...2,231,666

G

integrator complex subunit 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:129,084,681...129,130,669
Ensembl chr 1:132,714,200...132,759,842

G

integrator complex subunit 8

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:91,442,560...91,499,916
Ensembl chr 8:93,645,053...93,702,373

G

immunity related GTPase Q

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:40,533,711...40,538,157
Ensembl chr19:49,141,775...49,146,061

G

integrin subunit alpha D

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:23,539,562...23,572,705
Ensembl chr16:31,724,113...31,797,249

G

integrin subunit beta 6

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr2B:47,386,913...47,496,491
Ensembl chr2B:164,764,251...164,867,426

G

inter-alpha-trypsin inhibitor heavy chain 5

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:7,589,897...7,697,190
Ensembl chr10:7,570,497...7,677,254

G

ITPRIP like 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr2A:102,986,844...102,990,391
Ensembl chr2A:97,248,026...97,251,064

G

Janus kinase 1

severity

ISO

DNA:frameshift mutations

NCBI chr 1:64,083,562...64,315,909
Ensembl chr 1:65,973,904...66,024,991

G

junction plakoglobin

severity

ISO

protein:increased expression:tumor:significantly associated with capsular invasion (p=0.007 for all cases, p=0.015 for cases with Gleason score 5-7)
DNA,mRNA,protein:loss of heterozygosity, decreased expression:tumor:relative to either BPH or normal prostate

PMID:10206308 PMID:15781623

RGD:2291864 RGD:2291876

NCBI chr17:15,527,115...15,559,251
Ensembl chr17:15,747,163...15,777,479

G

lysine acetyltransferase 7

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:43,875,921...43,916,352
Ensembl chr17:48,605,488...48,645,784

G

katanin catalytic subunit A1 like 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr18:40,196,170...40,492,175
Ensembl chr18:43,758,249...43,850,517

G

potassium voltage-gated channel modifier subfamily F member 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr2A:10,906,060...10,908,818
Ensembl chr2A:11,055,090...11,060,758

G

potassium inwardly rectifying channel subfamily J member 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:123,649,466...123,680,149
Ensembl chr11:127,553,327...127,557,860

G

potassium inwardly rectifying channel subfamily J member 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr22:19,341,699...19,370,666
Ensembl chr22:37,163,760...37,165,097

G

potassium calcium-activated channel subfamily N member 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:130,052,903...130,218,977
Ensembl chr 1:133,666,876...133,828,366

G

potassium voltage-gated channel subfamily Q member 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:128,769,930...129,134,671
Ensembl chr 8:131,755,454...131,815,237

G

potassium voltage-gated channel subfamily Q member 5

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr 6:70,448,161...71,025,173
Ensembl chr 6:73,742,191...74,312,344

G

lysine demethylase 3A

ISO

mRNA:increased expression:prostate gland (human)
mRNA:increased expression:prostate (human)

PMID:20127736 PMID:22120715

RGD:9586733 RGD:9587486

NCBI chr2A:86,497,531...86,548,772

G

lysine demethylase 4A

ISO

mRNA:increased expression:prostate (human)

NCBI chr 1:42,949,977...43,005,684
Ensembl chr 1:44,325,624...44,380,163

G

lysine demethylase 4B

ISO

mRNA:increased expression:prostate (human)

NCBI chr19:3,986,296...4,172,359
Ensembl chr19:4,977,413...5,116,113

G

lysine demethylase 4C

severity

ISO

mRNA:increased expression:prostate gland (human)

NCBI chr 9:6,568,569...6,978,741
Ensembl chr 9:6,746,265...7,155,298

G

lysine demethylase 5A

ISO

mRNA:decreased expression:prostate gland (human)

NCBI chr12:342,555...452,161
Ensembl chr12:319,273...423,634

G

lysine demethylase 5B

severity

ISO

mRNA:increased expression:prostate gland (human)

NCBI chr 1:178,323,073...178,406,608
Ensembl chr 1:182,622,425...182,702,994

G

lysine demethylase 6A

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:37,313,000...37,548,630
Ensembl chr X:45,127,382...45,362,029

G

kinase insert domain receptor

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:68,813,894...68,861,018
Ensembl chr 4:75,377,375...75,427,109

G

KIAA1755 ortholog

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:34,536,041...34,584,652
Ensembl chr20:35,646,743...35,695,769

G

kinesin family member 12

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:85,189,613...85,197,157
Ensembl chr 9:113,556,850...113,564,524

G

kinesin family member 16B

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:16,229,429...16,532,735
Ensembl chr20:16,210,821...16,512,618

G

kinesin family member 5A

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr12:31,340,201...31,376,849
Ensembl chr12:31,599,376...31,635,327

G

KLF transcription factor 6

ISO

NCBI chr10:3,781,797...3,790,539
Ensembl chr10:3,789,893...3,796,379

G

kelch like family member 20

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:149,232,858...149,303,357
Ensembl chr 1:152,937,835...153,008,239

G

kallikrein related peptidase 10

susceptibility

ISO

DNA:SNP:exon:p.A50S (human)

NCBI chr19:47,980,177...47,987,617
Ensembl chr19:56,869,530...56,876,649

G

kallikrein related peptidase 13

ISO

protein:decreased expression:prostate

NCBI chr19:48,022,614...48,032,624
Ensembl chr19:56,912,192...56,920,749

G

kallikrein related peptidase 4

ISO

protein:increased expression:prostate gland

PMID:12370833 PMID:17545602

RGD:2314854 RGD:2314857

NCBI chr19:47,849,158...47,876,522
Ensembl chr19:56,764,073...56,768,169

G

kallikrein related peptidase 6

ISO

protein:decreased expression:prostate

NCBI chr19:47,925,017...47,936,314
Ensembl chr19:56,815,073...56,826,689

G

killin, p53 regulated DNA replication inhibitor

ISO

ClinVar Annotator: match by term: Prostate cancer

PMID:25741868 PMID:26467025 PMID:27535533

NCBI chr10:84,581,971...84,587,420

G

lysine methyltransferase 2A

ISO

mRNA:decreased expression:prostate gland (human)

NCBI chr11:113,273,198...113,364,404
Ensembl chr11:117,204,820...117,290,100

G

lysine methyltransferase 2B

ISO

mRNA:decreased expression:prostate gland (human)

NCBI chr19:32,647,815...32,668,656
Ensembl chr19:41,382,458...41,402,695

G

lysine methyltransferase 2C

ISO

mRNA:decreased expression:prostate gland (human)

NCBI chr 7:143,714,716...144,016,188
Ensembl chr 7:155,862,610...156,081,043

G

lysine methyltransferase 2D

ISO

mRNA:decreased expression:prostate gland (human)

NCBI chr12:39,689,463...39,731,904
Ensembl chr12:40,575,083...40,608,661

G

lysine methyltransferase 2E (inactive)

ISO

mRNA:decreased expression:prostate gland (human)

NCBI chr 7:97,001,250...97,099,956
Ensembl chr 7:109,734,808...109,832,851

G

lysine methyltransferase 5A

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:120,982,059...121,007,360

G

kinetochore associated 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:120,129,557...120,228,384
Ensembl chr12:124,351,508...124,448,624

G

keratinocyte proline rich protein

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:128,102,434...128,106,461
Ensembl chr 1:131,734,572...131,736,311

G

KRAS proto-oncogene, GTPase

ISO

OMIM:176807 | OMIM:300147 | OMIM:300704 | OMIM:601518 | OMIM:602759 | OMIM:608656 | OMIM:608658 | OMIM:609299 | OMIM:609558 | OMIM:610321 | OMIM:610997 | OMIM:611100 | OMIM:611868 | OMIM:611928 | OMIM:611955 | OMIM:611958 | OMIM:611959

NCBI chr12:61,062,689...61,108,524
Ensembl chr12:63,679,293...63,724,335

G

keratin 9

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:15,744,879...15,751,055
Ensembl chr17:15,963,459...15,967,939

G

laminin subunit alpha 5

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:58,673,850...58,677,760
Ensembl chr20:59,992,130...60,055,765

G

La ribonucleoprotein 1B

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:120,230,897...120,383,530
Ensembl chr 4:131,533,028...131,678,775

G

ligand dependent nuclear receptor corepressor

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:93,454,741...93,609,317
Ensembl chr10:97,067,801...97,106,845

G

lymphoid enhancer binding factor 1

ISO

associated with prostate cancer

NCBI chr 4:100,552,959...100,674,156
Ensembl chr 4:111,125,312...111,245,980

G

DNA ligase 4

treatment

ISO

NCBI chr13:89,336,434...89,347,418
Ensembl chr13:108,475,820...108,478,555

G

lectin, mannose binding 1 like

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:53,754,682...53,768,324
Ensembl chr15:73,373,160...73,386,050

G

leishmanolysin like peptidase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:195,396,514...195,477,580
Ensembl chr 3:205,268,896...205,348,412

G

AGBL carboxypeptidase 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:47,807,888...49,264,213
Ensembl chr 1:49,511,379...49,560,314
Ensembl chr 1:49,511,379...49,560,314

G

olfactory receptor 8K3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:51,556,139...51,557,077

G

putative protein ZNF815

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:5,378,188...5,401,189

G

olfactory receptor 2Z1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:8,027,916...8,029,403
Ensembl chr19:8,872,680...8,873,624

G

sulfotransferase 1A1

no_association

ISO

DNA:SNP:CDS:no association with the 638G->A, amino acid R213H polymorphism in a Japanese population
DNA, protein:SNP, increased activity:CDS:SULT1A1*1 high activity allele associated with higher prostate cancer risk, risk increases with increased consumption of well-done meat

PMID:14973106 PMID:18368507

RGD:1581454 RGD:2301050

G

keratin, type II cytoskeletal 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:36,083,858...36,089,521
Ensembl chr12:36,861,585...36,866,725

G

mucin-17

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:93,178,939...93,198,279

G

olfactory receptor 5AC2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:95,160,005...95,160,934
Ensembl chr 3:101,843,640...101,844,569

G

olfactory receptor 2T1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:224,108,483...224,109,592
Ensembl chr 1:229,552,860...229,553,969

G

solute carrier organic anion transporter family member 1B3

disease_progression

ISO

mRNA,protein:increased expression:prostate (human)

NCBI chr12:65,386,042...65,492,240

G

protein HIRA

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr22:2,087,846...2,191,192
Ensembl chr22:17,765,598...17,847,084

G

olfactory receptor 14A16

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:223,453,971...223,473,186
Ensembl chr 1:228,903,785...228,904,717

G

zinc-alpha-2-glycoprotein

ISO

protein:increased expression:serum

NCBI chr 7:91,999,717...92,009,066
Ensembl chr 7:105,432,782...105,442,219

G

olfactory receptor 6K2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:134,058,226...134,059,339
Ensembl chr 1:137,849,135...137,850,115

G

olfactory receptor 4C12

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:49,340,591...49,341,519
Ensembl chr11:50,013,316...50,014,245

G

olfactory receptor 1S2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:53,443,592...53,444,569
Ensembl chr11:56,906,610...56,907,587

G

taste receptor type 2 member 20

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:11,025,361...11,033,572
Ensembl chr12:11,292,936...11,293,865

G

olfactory receptor 5L1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:51,052,384...51,053,479

G

signal transducer and activator of transcription 5A

disease_progression

ISO

DNA:CNV: :prostate (human)

NCBI chr17:15,005,025...15,029,110
Ensembl chr17:15,228,465...15,251,783

G

protocadherin alpha-11

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:136,150,262...136,376,530
Ensembl chr 5:142,321,070...142,488,986

G

protocadherin alpha-2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

G

protocadherin alpha-7

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

Ensembl chr 5:142,301,336...142,316,338

G

myosin-8

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:41,231,081...41,262,671
Ensembl chr17:45,978,472...46,010,038

G

lon peptidase 2, peroxisomal

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:28,513,060...28,628,181
Ensembl chr16:47,405,018...47,511,124

G

LDL receptor related protein 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:31,713,938...31,799,287
Ensembl chr12:31,966,149...32,051,979

G

LDL receptor related protein 1B

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr2B:17,702,178...19,611,567
Ensembl chr2B:144,382,759...146,221,243

G

LDL receptor related protein 6

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:12,121,411...12,288,590
Ensembl chr12:12,508,108...12,657,973

G

LDL receptor related protein associated protein 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:3,663,649...3,683,450
Ensembl chr 4:3,646,179...3,666,098

G

microtubule actin crosslinking factor 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:38,369,021...38,771,911
Ensembl chr 1:39,820,394...40,096,558

G

mitotic arrest deficient 1 like 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:11423979 PMID:25741868

NCBI chr 7:2,070,299...2,502,471
Ensembl chr 7:2,187,104...2,601,328

G

membrane associated guanylate kinase, WW and PDZ domain containing 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:69,943,704...71,395,176
Ensembl chr 7:83,758,512...84,760,872

G

MAM domain containing 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:54,579,265...54,755,474
Ensembl chr 9:68,804,009...68,980,269

G

mastermind like transcriptional coactivator 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:174,886,694...174,931,153
Ensembl chr 5:182,230,351...182,242,296

G

mastermind like domain containing 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:140,009,726...140,163,667
Ensembl chr X:149,945,753...150,098,431

G

mitogen-activated protein kinase kinase 5

ISO

protein:increased expression

NCBI chr15:46,493,139...46,760,271
Ensembl chr15:64,761,394...65,029,655

G

mitogen-activated protein kinase kinase 7

ISO

mRNA:splice variant:exon 2: (human)

NCBI chr19:7,205,124...7,215,776
Ensembl chr19:8,057,598...8,066,512

G

mitogen-activated protein kinase kinase kinase 7

ISO

DNA:deletion

NCBI chr 6:88,398,329...88,470,926
Ensembl chr 6:91,664,263...91,737,468

G

mitogen-activated protein kinase 10

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:78,326,129...78,756,794
Ensembl chr 4:89,059,579...89,392,196

G

mitogen-activated protein kinase 7

ISO

NCBI chr17:31,729,429...31,736,216
Ensembl chr17:36,894,146...36,899,969

G

microtubule associated protein tau

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:11,373,220...11,506,669
Ensembl chr17:11,458,159...11,523,129

G

MCC regulator of WNT signaling pathway

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:108,382,066...108,845,503
Ensembl chr 5:114,184,907...114,647,847

G

magnesium dependent phosphatase 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:4,987,859...4,992,300
Ensembl chr14:23,112,062...23,116,606

G

mediator complex subunit 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:17,836,350...17,883,610
Ensembl chr17:18,050,474...18,095,118

G

matrix metallopeptidase 13

disease_progression

ISO

protein:increased expression:plasma:higher concentration in patients with metastases vs non-metastatic PCa, BPH or control patients

NCBI chr11:97,890,811...97,902,778
Ensembl chr11:101,377,001...101,387,679

G

matrix metallopeptidase 15

disease_progression

ISO

NCBI chr16:38,304,856...38,326,193
Ensembl chr16:57,433,813...57,457,122

G

matrix metallopeptidase 2

disease_progression

ISO

protein:increased expression:prostate gland

NCBI chr16:35,711,866...35,738,881
Ensembl chr16:54,812,694...54,844,279

G

matrix metallopeptidase 7

ISO

NCBI chr11:97,467,037...97,477,305
Ensembl chr11:100,960,032...100,971,099

G

mitochondrial ribosomal protein L46

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:67,151,616...67,159,521
Ensembl chr15:86,359,188...86,367,113

G

mutS homolog 2

disease_progression

ISO

NCBI chr2A:47,524,468...47,602,376
Ensembl chr2A:48,447,207...48,554,461

G

mutS homolog 6

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:25741868 PMID:28492532

NCBI chr2A:47,901,591...47,926,662
Ensembl chr2A:48,824,350...48,849,779

G

microseminoprotein beta

ISO

OMIM:176807 | OMIM:300147 | OMIM:300704 | OMIM:601518 | OMIM:602759 | OMIM:608656 | OMIM:608658 | OMIM:609299 | OMIM:609558 | OMIM:610321 | OMIM:610997 | OMIM:611100 | OMIM:611868 | OMIM:611928 | OMIM:611955 | OMIM:611958 | OMIM:611959

NCBI chr10:43,187,155...43,200,150
Ensembl chr10:46,449,079...46,464,007

G

macrophage scavenger receptor 1

susceptibility

ISO

DNA:SNPs
ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:12244320 PMID:12958598 PMID:17903305 PMID:21791690 PMID:24082139 More...

NCBI chr 8:15,335,795...15,421,472
Ensembl chr 8:12,088,873...12,175,927

G

MDM2 binding protein

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:117,135,172...117,213,360
Ensembl chr 8:119,903,633...119,980,911

G

methylenetetrahydrofolate reductase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:10,548,196...10,568,174
Ensembl chr 1:11,766,334...11,785,419

G

mitochondrial nucleoid associated protein 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:67,160,844...67,177,565
Ensembl chr17:72,615,831...72,633,034

G

mechanistic target of rapamycin kinase

treatment

ISO

NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841

G

mucin 1, cell surface associated

severity

ISO

NCBI chr 1:130,533,508...130,537,866
Ensembl chr 1:134,141,969...134,145,850

G

mucin 6, oligomeric mucus/gel-forming

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:1,035,447...1,071,791
Ensembl chr11:1,077,867...1,106,927

G

MX dynamin like GTPase 1

susceptibility

ISO

DNA:SNP:promoter:-g.88G>T (rs2071430) (human)

NCBI chr21:27,756,768...27,795,307
Ensembl chr21:41,095,928...41,123,019

G

MAX interactor 1, dimerization protein

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:106,799,511...106,878,697

G

matrix remodeling associated 5

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

Ensembl chr X:3,248,134...3,285,917

G

MYC proto-oncogene, bHLH transcription factor

severity
susceptibility

ISO

protein:increased expression:prostate gland (human)
DNA:snp:intron:IVS1-355T>A rs3891248 (human)

PMID:18483343 PMID:20140016

RGD:7207432 RGD:7240541

NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863

G

MYC binding protein 2

disease_progression

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:26408707

NCBI chr13:58,262,251...58,544,819
Ensembl chr13:77,306,509...77,586,843

G

myosin heavy chain 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:25741868 PMID:28492532 PMID:31030430

NCBI chr17:40,974,636...41,025,511
Ensembl chr17:45,746,301...45,772,735

G

myosin light chain kinase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:120,711,705...120,983,432
Ensembl chr 3:127,614,173...127,793,261

G

myosin XVI

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:89,754,451...90,338,658
Ensembl chr13:108,922,993...109,473,752

G

myosin XVIIIA

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:27,593,787...27,700,801
Ensembl chr17:28,116,279...28,208,301

G

myosin IA

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:31,875,570...31,899,279
Ensembl chr12:32,130,708...32,152,335

G

myosin VI

ISO

protein:increased expression:prostate gland epithelium, perinuclear region of cytoplasm

NCBI chr 6:73,593,794...73,764,352
Ensembl chr 6:76,951,634...77,048,796

G

myocardin

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:38,880,120...38,983,246
Ensembl chr17:43,584,259...43,681,659

G

myotilin

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:133,254,644...133,274,615
Ensembl chr 5:139,386,101...139,411,960

G

myelin regulatory factor

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:57,052,219...57,088,105
Ensembl chr11:60,412,780...60,448,579

G

NSF attachment protein beta

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:23,316,153...23,363,142
Ensembl chr20:23,667,469...23,713,935

G

N-acetyltransferase 1

susceptibility

ISO

DNA:polymorphism

NCBI chr 8:17,425,852...17,439,684
Ensembl chr 8:14,386,481...14,392,462

G

N-acetyltransferase 2

susceptibility

ISO

DNA:polymorphism

NCBI chr 8:17,606,445...17,623,397
Ensembl chr 8:14,575,455...14,576,327

G

nibrin

susceptibility

ISO

DNA:deletion, loss of heterozygosity
ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: Prostate cancer

PMID:14973119 PMID:23265383 PMID:23555315 PMID:25741868 PMID:26467025 More...

NCBI chr 8:86,622,797...86,674,202
Ensembl chr 8:88,575,198...88,626,307

G

nuclear receptor coactivator 1

disease_progression

ISO

NCBI chr2A:24,485,068...24,764,135
Ensembl chr2A:24,733,117...24,859,488

G

nuclear receptor coactivator 2

ISO

mRNA:increased expression:prostate (human)

NCBI chr 8:66,632,139...66,929,526
Ensembl chr 8:68,293,018...68,400,479

G

nuclear receptor coactivator 3

ISO

mRNA:increased expression:prostate (human)

NCBI chr20:43,838,227...43,992,407
Ensembl chr20:45,000,422...45,073,549

G

nuclear receptor coactivator 4

severity

ISO

protein:increased expression:prostate gland
mRNA:decreased expression:prostate gland

PMID:12368219 PMID:15166229

RGD:2293534 RGD:2293535

NCBI chr10:43,159,014...43,184,558
Ensembl chr10:46,420,952...46,443,223

G

NECAP endocytosis associated 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:15,578,444...15,597,823
Ensembl chr 1:16,568,847...16,588,213

G

NIMA related kinase 9

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:55,633,667...55,678,670
Ensembl chr14:74,478,387...74,522,320

G

negative elongation factor complex member C/D

disease_progression

ISO

NCBI chr20:55,332,309...55,346,167
Ensembl chr20:56,693,685...56,706,458

G

neural EGFL like 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:20,697,153...21,600,601
Ensembl chr11:20,607,526...21,508,486

G

neuropilin and tolloid like 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:27,343,333...27,405,173
Ensembl chr16:46,235,165...46,284,344

G

nuclear factor kappa B subunit 1

treatment
susceptibility

ISO

DNA:SNPs, haplotype: :multiple
DNA:indel:promoter

PMID:26068031 PMID:26788504 PMID:28797847

RGD:11054182 RGD:11554936 RGD:13506729

NCBI chr 4:94,925,048...95,040,849
Ensembl chr 4:105,589,062...105,704,098

G

NFKB inhibitor alpha

susceptibility
disease_progression
no_association

ISO

DNA:SNPs:promoter:-826C>T, -881A>G (human)
ClinVar Annotator: match by term: Malignant tumor of prostate
protein:increased serine phosphorylation
DNA:SNPs: :rs2233406, rs3138053 (human)
DNA:polymorphism:3' UTR

PMID:23093296 PMID:26068031 PMID:26834482

RGD:11054182 RGD:13506766 RGD:13506767

NCBI chr14:16,155,331...16,158,588

G

NHS actin remodeling regulator

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:9,988,584...10,359,110
Ensembl chr X:17,358,416...17,728,178

G

sodium/potassium transporting ATPase interacting 2

ISO

mRNA, protein:decreased expression:prostate

NCBI chr 6:121,590,732...122,611,445
Ensembl chr 6:125,713,247...126,729,668

G

NK3 homeobox 1

ISO

OMIM:176807 | OMIM:300147 | OMIM:300704 | OMIM:601518 | OMIM:602759 | OMIM:608656 | OMIM:608658 | OMIM:609299 | OMIM:609558 | OMIM:610321 | OMIM:610997 | OMIM:611100 | OMIM:611868 | OMIM:611928 | OMIM:611955 | OMIM:611958 | OMIM:611959

NCBI chr 8:22,926,145...22,930,396
Ensembl chr 8:19,863,275...19,864,942

G

NLR family pyrin domain containing 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr17:5,562,129...5,667,765
Ensembl chr17:5,542,007...5,623,091

G

NLR family pyrin domain containing 7

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:19066229 PMID:21507883 PMID:24105752

NCBI chr19:51,966,886...51,990,971
Ensembl chr19:60,662,184...60,677,844

G

NMD3 ribosome export adaptor

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:158,235,646...158,267,316
Ensembl chr 3:166,282,258...166,313,798

G

nitric oxide synthase 3

disease_progression

ISO

DNA:polymorphism:exon:p.E298D (human)

NCBI chr 7:142,577,334...142,600,702
Ensembl chr 7:154,730,009...154,755,233

G

notch receptor 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:7732783 PMID:15364702 PMID:16328531 PMID:23265383 PMID:25033846 More...

NCBI chr19:14,692,571...14,733,758
Ensembl chr19:15,678,674...15,715,080

G

nuclear receptor subfamily 3 group C member 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:138,634,278...139,089,171
Ensembl chr 5:144,741,452...144,865,269

G

NRAS proto-oncogene, GTPase

disease_progression

ISO

NCBI chr 1:87,837,146...87,850,013
Ensembl chr 1:122,890,505...122,903,585

G

netrin 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:93,253,945...93,387,184
Ensembl chr12:96,643,804...96,776,346

G

NACHT and WD repeat domain containing 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:16,209,324...16,305,897
Ensembl chr19:17,202,805...17,281,335

G

8-oxoguanine DNA glycosylase

susceptibility

ISO

DNA:missense mutation:exon:p.S326C (1245C>G) (rs1052133) (human)
DNA:missense mutation:cds:p.S326C (human)

PMID:19914098 PMID:24649009

RGD:8657136 RGD:8657378

NCBI chr 3:9,702,311...9,742,283
Ensembl chr 3:9,940,955...9,947,335

G

oncoprotein induced transcript 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:69,440,607...69,480,590
Ensembl chr10:71,904,656...71,943,418

G

Obg like ATPase 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr2B:61,349,811...61,525,617
Ensembl chr2B:178,809,783...178,981,763

G

olfactomedin like 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:88,575,167...88,577,992
Ensembl chr 1:123,624,824...123,627,681

G

OXA1L mitochondrial inner membrane insertase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:3,584,220...3,589,360
Ensembl chr14:21,683,983...21,689,101

G

p21 (RAC1) activated kinase 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:36,224,442...36,278,371
Ensembl chr19:44,816,601...44,825,827

G

PALM2 and AKAP2 fusion

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:80,794,036...81,328,270
Ensembl chr 9:109,413,921...109,494,631

G

par-3 family cell polarity regulator

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:34,225,791...34,933,907
Ensembl chr10:34,808,380...35,393,287

G

protocadherin alpha 10

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

G

protocadherin alpha 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

Ensembl chr 5:142,280,707...142,283,181

G

protocadherin alpha 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

Ensembl chr 5:142,286,433...142,289,088

G

protocadherin beta 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:136,413,938...136,423,568
Ensembl chr 5:142,530,521...142,532,977

G

pecanex 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:51,494,857...51,703,882
Ensembl chr14:70,399,733...70,565,992

G

phosphodiesterase 1C

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:32,225,293...33,037,627
Ensembl chr 7:32,343,701...33,029,405

G

phosphodiesterase 3A

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:20,380,213...20,690,540
Ensembl chr12:20,763,999...21,064,391

G

phosphodiesterase 6B

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

Ensembl chr 4:646,516...701,680

G

phosphodiesterase 7B

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:133,615,008...133,960,120
Ensembl chr 6:137,707,863...138,047,756

G

platelet derived growth factor receptor beta

ISO

NCBI chr 5:145,538,330...145,580,312
Ensembl chr 5:151,543,891...151,585,530

G

pyruvate dehydrogenase kinase 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:87,540,600...87,553,673
Ensembl chr 7:101,128,060...101,141,157

G

pyruvate dehydrogenase phosphatase catalytic subunit 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:47,195,850...47,205,214
Ensembl chr16:66,301,453...66,303,042

G

3-phosphoinositide dependent protein kinase 1

treatment

ISO

NCBI chr16:1,394,447...1,463,735

G

phosphatidylethanolamine binding protein 1

ISO

NCBI chr12:115,716,953...115,726,412
Ensembl chr12:119,093,952...119,105,054

G

pyroglutamyl-peptidase I

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:17,819,337...17,848,683
Ensembl chr19:18,792,341...18,812,697

G

PHD finger protein 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:64,700,151...64,803,737
Ensembl chr 9:92,815,392...92,863,817

G

PHD finger protein 8

ISO

mRNA:increased expression:prostate (human)

NCBI chr X:46,144,815...46,250,594
Ensembl chr X:54,250,970...54,355,913

G

PH domain and leucine rich repeat protein phosphatase 1

disease_progression

ISO

mRNA:decreased expression:tumor:lower in high versus low Gleason score tumors (p<0.05 compared to at least one housekeeping gene)

NCBI chr18:56,084,851...56,338,551

G

phosphatidylinositol glycan anchor biosynthesis class H

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:48,160,062...48,178,253
Ensembl chr14:67,045,451...67,056,371

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

ISO

ClinVar Annotator: match by term: Prostate cancer

PMID:15520168 PMID:25741868

NCBI chr 3:176,182,765...176,272,024
Ensembl chr 3:184,355,785...184,441,977

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

treatment
disease_progression

ISO

PMID:18372911 PMID:20103642

RGD:13506809 RGD:13506810

NCBI chr 3:135,685,120...135,867,096
Ensembl chr 3:143,288,563...143,431,314

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:98,841,974...98,885,446
Ensembl chr 7:111,570,148...111,611,614

G

phosphoinositide-3-kinase regulatory subunit 1

disease_progression

ISO

mRNA:decreased expression:tumor:lower in high versus low Gleason score tumors (p<0.05 compared to at least one housekeeping gene)
ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:18336616 PMID:23265383

NCBI chr 5:45,701,219...45,786,652
Ensembl chr 5:47,267,286...47,350,960

G

phosphoinositide-3-kinase regulatory subunit 2

ISO

NCBI chr19:17,632,265...17,649,664
Ensembl chr19:18,611,179...18,624,177

G

paired like homeodomain 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:103,112,624...103,137,356

G

polycystin 2 like 1, transient receptor potential cation channel

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:96,889,228...96,932,177
Ensembl chr10:100,370,083...100,412,366

G

PKHD1 ciliary IPT domain containing fibrocystin/polyductin

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr 6:51,166,516...51,635,057
Ensembl chr 6:52,435,462...52,903,309

G

plasminogen activator, urokinase

severity

ISO

protein:increased expression:serum (human)

NCBI chr10:70,433,340...70,441,569
Ensembl chr10:73,105,895...73,113,136

G

phospholipase B1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr2A:28,502,449...28,650,348
Ensembl chr2A:28,584,636...28,730,640

G

phospholipase C beta 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:9,042,127...9,454,207
Ensembl chr20:9,192,061...9,456,443

G

pleckstrin homology domain containing A4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:45,837,738...45,868,961
Ensembl chr19:54,886,850...54,918,334

G

pleckstrin homology and RhoGEF domain containing G1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:148,411,676...148,657,616
Ensembl chr 6:153,240,586...153,362,070

G

pleckstrin homology and RhoGEF domain containing G4B

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

Ensembl chr 5:236,047...324,006

G

prostate transmembrane protein, androgen induced 1

disease_progression

ISO

NCBI chr20:53,989,384...54,052,151
Ensembl chr20:55,267,089...55,329,347

G

PMS1 homolog 2, mismatch repair system component

disease_progression

ISO

NCBI chr 7:7,433,031...7,459,560
Ensembl chr 7:6,167,403...6,202,984

G

podocan

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:52,334,363...52,358,127
Ensembl chr 1:53,940,073...53,955,393

G

DNA polymerase kappa

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:25741868 PMID:26046662

NCBI chr 5:39,700,659...39,788,727
Ensembl chr 5:40,311,526...40,401,003

G

DNA polymerase nu

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:2,214,154...2,385,094
Ensembl chr 4:2,122,309...2,292,431

G

paraoxonase 1

ISO

protein:increased activity:serum (human)

NCBI chr 7:87,253,476...87,279,650
Ensembl chr 7:100,841,286...100,867,493

G

diphosphoinositol pentakisphosphate kinase 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:98,475,410...98,558,189
Ensembl chr 5:104,175,883...104,258,688

G

protein phosphatase 1 regulatory subunit 3C

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:88,377,396...88,382,205
Ensembl chr10:91,900,112...91,904,764

G

protein phosphatase 2 catalytic subunit alpha

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:129,599,606...129,629,312
Ensembl chr 5:135,751,958...135,765,786

G

protein phosphatase 2 regulatory subunit B'gamma

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:82,383,086...82,549,822
Ensembl chr14:102,206,396...102,372,978

G

protein phosphatase 6 regulatory subunit 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr22:30,572,446...30,690,242
Ensembl chr22:49,600,643...49,674,482

G

PPARG related coactivator 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:98,736,964...98,754,339
Ensembl chr10:102,205,240...102,221,546

G

phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1

ISO

protein:increased expression:prostate, lymph node

NCBI chr20:44,965,850...45,169,891
Ensembl chr20:46,033,937...46,226,500

G

phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:64,489,817...64,769,602
Ensembl chr 8:66,215,974...66,430,138

G

proline rich protein HaeIII subfamily 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:10,874,083...11,197,758
Ensembl chr12:11,234,409...11,235,362

G

protein kinase D1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:10,353,284...10,707,841
Ensembl chr14:28,496,282...28,650,030

G

peripherin 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:42,284,818...42,316,150
Ensembl chr 6:43,582,317...43,608,011

G

serine protease 22

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:1,790,787...1,797,025

G

proteasome 26S subunit, ATPase 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:70,873,846...70,889,988
Ensembl chr14:90,225,405...90,241,641

G

phosphatase and tensin homolog

disease_progression

ISO

mRNA:decreased expression:tumor:lower in high versus low Gleason score tumors (p<0.05 compared to at least one housekeeping gene)
ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: Prostate cancer
DNA:deletion

RGD
ClinVar
OMIM

PMID:9259288 PMID:9399897 PMID:9467011 PMID:9856571 PMID:10232405 More...

RGD:2292502 RGD:2301729

NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605

G

prostaglandin-endoperoxide synthase 2

susceptibility

ISO

DNA:SNP:promoter:-1195G>A (human)

NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519

G

protein tyrosine kinase 2

ISO

protein:increased expression:prostate gland

NCBI chr 8:137,330,777...137,677,306
Ensembl chr 8:140,412,773...140,684,898

G

protein tyrosine kinase 2 beta

severity

ISO

protein:decreased expression:prostate gland

NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474

G

protein tyrosine phosphatase non-receptor type 21

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:69,085,843...69,174,659
Ensembl chr14:88,444,261...88,528,951

G

protein tyrosine phosphatase non-receptor type 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:80,528,896...80,651,629
Ensembl chr 9:108,699,761...108,787,464

G

protein tyrosine phosphatase receptor type D

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:8,113,171...10,420,732
Ensembl chr 9:8,288,569...8,831,227

G

protein tyrosine phosphatase receptor type N2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:149,158,513...150,390,077
Ensembl chr 7:160,851,703...161,756,325

G

pyrroline-5-carboxylate reductase 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:140,356,586...140,362,972
Ensembl chr 8:143,371,748...143,378,032

G

pyrin and HIN domain family member 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:134,283,998...134,329,531
Ensembl chr 1:138,081,611...138,127,115

G

RAB11 family interacting protein 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:25,265,176...25,411,124
Ensembl chr17:26,006,251...26,146,947

G

RAB33A, member RAS oncogene family

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr X:119,298,428...119,311,625
Ensembl chr X:129,591,222...129,605,214

G

Rac family small GTPase 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr22:18,138,517...18,159,023
Ensembl chr22:35,973,229...35,992,026

G

RAD50 double strand break repair protein

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:26467025 PMID:28492532 PMID:33339169

NCBI chr 5:127,972,630...128,059,911
Ensembl chr 5:134,134,495...134,222,261

G

Raf-1 proto-oncogene, serine/threonine kinase

disease_progression

ISO

NCBI chr 3:12,510,084...12,590,598
Ensembl chr 3:12,853,415...12,932,871

G

Rap guanine nucleotide exchange factor like 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:17,093,714...17,111,187
Ensembl chr17:17,315,114...17,335,258

G

Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr2B:90,664,717...90,766,088
Ensembl chr2B:208,765,847...208,865,624

G

RAS protein activator like 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:153,609,277...153,986,155
Ensembl chr 1:157,303,646...157,670,415

G

Ras association domain family member 1

disease_progression

ISO

DNA:hypermethylation:promoter

NCBI chr 3:50,255,897...50,267,042
Ensembl chr 3:51,491,548...51,502,392

G

RB transcriptional corepressor 1

ISO

DNA:loss of heterozygosity

NCBI chr13:29,453,872...29,624,665
Ensembl chr13:48,155,795...48,324,575

G

RB associated KRAB zinc finger

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:5,304,827...5,328,372
Ensembl chr 7:5,344,120...5,356,307

G

regulator of chromosome condensation 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:16,353,770...16,386,810
Ensembl chr 1:17,409,432...17,432,031

G

RERG like

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:18,071,002...18,080,326
Ensembl chr12:18,456,879...18,466,282

G

Rho related BTB domain containing 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:22,246,075...22,269,443
Ensembl chr 8:19,183,931...19,209,420

G

RIPOR family member 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:46,929,641...47,037,795
Ensembl chr20:48,058,773...48,164,971

G

ring finger protein, LIM domain interacting

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:63,834,345...63,865,874
Ensembl chr X:73,959,365...73,982,412

G

ribonuclease L

ISO

ClinVar Annotator: match by term: Prostate cancer

PMID:11799394 PMID:25741868 PMID:28492532

NCBI chr 1:158,092,346...158,108,026
Ensembl chr 1:161,741,645...161,760,045

G

ribosomal protein L10 like

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:27,254,150...27,255,381
Ensembl chr14:45,565,079...45,565,723

G

ribosomal protein S6 kinase C1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:188,622,154...188,834,327
Ensembl chr 1:193,479,905...193,689,809

G

RNA pseudouridine synthase domain containing 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

Ensembl chr16:800,191...806,007

G

regulator of telomere elongation helicase 1

susceptibility

ISO

DNA:SNP:cds:rs2297441|rs3208008 (human)

Ensembl chr20:61,581,331...61,618,718

G

rubicon like autophagy enhancer

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:26,594,545...26,600,412

G

RUN domain containing 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:14,331,354...14,344,768
Ensembl chr17:14,559,032...14,572,898

G

S100 calcium binding protein A3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:128,902,495...128,904,247
Ensembl chr 1:132,531,579...132,533,508

G

scaffold attachment factor B2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:4,604,150...4,639,991
Ensembl chr19:5,539,679...5,575,560

G

strawberry notch homolog 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:120,892,270...120,962,576
Ensembl chr12:125,121,471...125,179,151

G

sodium channel epithelial 1 subunit alpha

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:6,475,723...6,506,443

G

secernin 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:30,550,199...30,619,197
Ensembl chr 7:30,667,229...30,736,129

G

signal peptide, CUB domain and EGF like domain containing 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:34,776,605...34,815,808
Ensembl chr 6:35,872,590...35,911,272

G

sidekick cell adhesion molecule 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:3,557,241...4,521,234
Ensembl chr 7:3,948,607...4,584,591

G

serpin family B member 13

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr18:56,946,828...56,958,702
Ensembl chr18:60,258,085...60,270,607

G

serpin family B member 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr18:56,996,437...57,003,489

G

SET domain containing 5

severity

ISO

NCBI chr 3:9,350,026...9,430,760
Ensembl chr 3:9,592,517...9,672,306

G

SET domain bifurcated histone lysine methyltransferase 1

ISO

mRNA, protein:increased expression:prostate gland (human)

NCBI chr 1:126,275,719...126,314,043
Ensembl chr 1:129,925,009...129,962,442

G

seizure related 6 homolog like

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr22:7,230,597...7,445,397
Ensembl chr22:25,077,259...25,163,881

G

splicing factor 3b subunit 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:54,442,510...54,490,950
Ensembl chr16:70,361,068...70,410,042

G

serum/glucocorticoid regulated kinase family member 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:63,210,279...63,403,991
Ensembl chr 8:64,982,973...65,067,296

G

small G protein signaling modulator 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:2,328,517...2,372,408
Ensembl chr17:2,213,192...2,256,638

G

SHC binding and spindle associated 1 like

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:158,416,397...158,470,003
Ensembl chr 1:162,067,996...162,629,927

G

sucrase-isomaltase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:161,961,038...162,104,054
Ensembl chr 3:170,057,750...170,154,502

G

sialic acid binding Ig like lectin 6

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:48,459,184...48,474,451

G

sirtuin 1

disease_progression

ISO

NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069

G

SKI3 subunit of superkiller complex

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:19,794,151...19,892,000
Ensembl chr 5:19,939,324...20,036,558

G

SKI like proto-oncogene

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:167,372,104...167,411,287
Ensembl chr 3:175,562,007...175,600,181

G

S-phase kinase associated protein 2

disease_progression

ISO

NCBI chr 5:74,179,608...74,211,563
Ensembl chr 5:79,461,018...79,492,311

G

solute carrier family 13 member 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:25741868 PMID:28492532

NCBI chr20:42,890,251...43,018,635
Ensembl chr20:43,977,568...44,068,886

G

solute carrier family 16 member 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:63,673,992...63,787,011
Ensembl chr X:73,791,200...73,903,727

G

solute carrier family 25 member 22

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:807,886...815,770
Ensembl chr11:851,998...858,121

G

solute carrier family 25 member 32

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:100,054,560...100,071,016
Ensembl chr 8:102,210,068...102,226,732

G

solute carrier family 25 member 47

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:80,927,765...80,952,992
Ensembl chr14:100,258,391...100,265,448

G

SLC2A4 regulator

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

G

solute carrier family 30 member 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:25,296,643...25,304,751
Ensembl chr 1:26,359,575...26,370,803

G

solute carrier family 34 member 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:172,685,862...172,700,440
Ensembl chr 5:179,748,492...179,762,975

G

solute carrier family 35 member C1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:45,758,274...45,766,991
Ensembl chr11:46,250,488...46,259,409

G

solute carrier family 35 member G1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:90,641,079...90,696,621
Ensembl chr10:94,152,493...94,162,201

G

solute carrier family 46 member 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:9,987,309...10,007,152
Ensembl chr13:28,327,633...28,347,534

G

solute carrier family 5 member 2

ISO

ClinVar Annotator: match by term: Prostate cancer

PMID:23265383 PMID:25741868

NCBI chr16:23,474,992...23,482,603
Ensembl chr16:31,853,602...31,861,261

G

solute carrier family 5 member 7

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr2A:93,917,086...93,944,308
Ensembl chr2A:109,017,805...109,046,860

G

solute carrier family 6 member 9

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr 1:43,298,326...43,333,345
Ensembl chr 1:44,664,839...44,704,882

G

solute carrier family 8 member A3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:50,634,091...50,779,712

G

SMAD family member 3

disease_progression

ISO

protein:increased expression:tumor:significantly elevated in 53/67 (79%, p=0.0002) overall, in 23/35 with Gleason score 6-7(66%) and 30/32 with Gleason score 8-10 (94%, p=0.0062); by immunohistochemistry

NCBI chr15:46,013,764...46,143,126
Ensembl chr15:64,284,949...64,414,185

G

SMAD family member 9

ISO

protein:altered localization

NCBI chr13:18,055,427...18,130,571
Ensembl chr13:36,486,597...36,521,646

G

SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2

disease_progression

ISO

NCBI chr 9:1,818,004...1,997,652
Ensembl chr 9:2,013,237...2,189,409

G

SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4

disease_progression
no_association

ISO

absence of somatic mutations in the samples used

PMID:12684665 PMID:17075831

RGD:2302527 RGD:2302528

NCBI chr19:10,515,216...10,616,155
Ensembl chr19:11,250,006...11,334,952

G

SWI/SNF related BAF chromatin remodeling complex subunit C2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:32,726,150...32,753,366
Ensembl chr12:32,977,879...33,004,144

G

single-strand-selective monofunctional uracil-DNA glycosylase 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:34,564,624...34,572,063
Ensembl chr12:35,288,412...35,296,670

G

small nuclear ribonucleoprotein polypeptide E

severity

ISO

mRNA:increased expression:prostate gland (human)

NCBI chr 1:179,466,263...179,474,779
Ensembl chr 1:183,755,392...183,764,937

G

suppressor of cytokine signaling 1

ISO

DNA:hypermethylation

NCBI chr16:10,196,432...10,198,205

G

sorbin and SH3 domain containing 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:91,922,292...92,172,339
Ensembl chr10:95,432,824...95,559,022

G

sortilin related VPS10 domain containing receptor 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:103,164,581...103,753,754

G

SOS Ras/Rac guanine nucleotide exchange factor 1

ISO

NCBI chr2A:39,019,046...39,162,248
Ensembl chr2A:39,773,760...39,911,961

G

SRY-box transcription factor 9

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:66,028,737...66,034,122

G

spermatogenesis associated 18

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:71,863,549...71,911,079
Ensembl chr 4:78,416,684...78,464,191

G

sperm antigen with calponin homology and coiled-coil domains 1 like

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr22:5,078,435...5,224,090
Ensembl chr22:21,943,630...22,089,686

G

serine peptidase inhibitor Kazal type 1

severity

ISO

protein:increased expression:prostate gland, serum

NCBI chr 5:143,273,137...143,287,745

G

speckle type BTB/POZ protein

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:25741868

NCBI chr17:43,685,913...43,765,277
Ensembl chr17:48,417,634...48,440,623

G

SRC proto-oncogene, non-receptor tyrosine kinase

disease_progression

ISO

protein:increased tyrosine phosphorylation:prostate gland, membrane

NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634

G

steroid 5 alpha-reductase 1

disease_progression

ISO

mRNA:increased expression:prostate gland (rat)
protein:increased expression:prostate gland

PMID:16818707 PMID:17720776

RGD:2302521 RGD:2302523

NCBI chr 5:6,953,795...6,996,010
Ensembl chr 5:6,629,093...6,664,264

G

steroid 5 alpha-reductase 2

susceptibility

ISO

mRNA:decreased expression:prostate gland
DNA:missense mutation:cds:p.A49T (human)

PMID:10501358 PMID:12949937

RGD:2302560 RGD:4891929

NCBI chr2A:31,542,646...31,597,394
Ensembl chr2A:31,610,487...31,665,718

G

sterol regulatory element binding transcription factor 2

disease_progression

ISO

NCBI chr22:22,725,790...22,799,749
Ensembl chr22:40,811,459...40,884,947

G

single stranded DNA binding protein 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:33,535,213...33,859,595
Ensembl chr 5:33,852,266...34,170,615

G

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr10:17,632,154...17,771,252
Ensembl chr10:17,909,556...18,041,946

G

signal transducer and activator of transcription 3

treatment

ISO

NCBI chr17:14,928,689...15,003,644
Ensembl chr17:15,152,358...15,227,067

G

signal transducer and activator of transcription 6

disease_progression

ISO

mRNA, protein:increased expression:fibromuscular stroma, malignant epithelia:correlated with high histological grade and increased tumor size

Ensembl chr12:32,068,679...32,085,099

G

syntaxin 8

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:42,076,600...42,403,334
Ensembl chr17:46,816,859...47,141,816

G

syntaxin binding protein 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:98,731,527...98,811,608
Ensembl chr 9:127,434,080...127,486,152

G

SUFU negative regulator of hedgehog signaling

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr10:99,107,516...99,231,761
Ensembl chr10:102,571,886...102,696,472

G

sulfotransferase family 2A member 1

severity
no_association

ISO

DNA:SNP:intron: (rs2547238) (human)
DNA:missense mutations:cds:p.A63P (187G>C), p.A261T (781G>A) (human)

PMID:16617014 PMID:22542949

RGD:6893648 RGD:6893649

NCBI chr19:44,864,747...44,880,688
Ensembl chr19:53,517,248...53,532,573

G

synaptic vesicle glycoprotein 2B

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:69,793,642...69,989,339
Ensembl chr15:89,114,744...89,184,370

G

synaptonemal complex protein 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:56,219,579...56,289,382
Ensembl chr20:57,571,935...57,629,016

G

synaptogyrin 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr22:20,253,936...20,289,470
Ensembl chr22:38,071,261...38,104,931

G

TAO kinase 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr12:115,730,619...115,954,149
Ensembl chr12:119,109,642...119,226,502

G

transcription factor 3

severity

ISO

Ensembl chr19:1,582,297...1,622,025

G

transcription factor 7

severity

ISO

NCBI chr 5:129,518,134...129,549,972
Ensembl chr 5:135,671,095...135,702,734

G

transcription factor 7 like 2

disease_progression

ISO

DNA:SNP: :rs7903146 (human)
DNA:SNPs: :rs7094463, rs10749127, rs11196224 (human)

PMID:24961829 PMID:25678841

RGD:13506821 RGD:13506825

NCBI chr10:109,541,524...109,759,499
Ensembl chr10:112,978,167...113,192,281

G

telomerase reverse transcriptase

ISO

mRNA:increased expression:plasma

Ensembl chr 5:1,300,960...1,338,872

G

testis expressed 14, intercellular bridge forming factor

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:52,627,335...52,768,926
Ensembl chr17:57,480,369...57,621,055

G

transferrin

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:130,799,063...130,830,227
Ensembl chr 3:138,274,159...138,305,476

G

trefoil factor 1

disease_progression

ISO

mRNA:increased expression:prostate gland
protein:increased expression:plasma

PMID:10458410 PMID:16467092

RGD:2291999 RGD:2298571

NCBI chr21:28,669,323...28,673,556
Ensembl chr21:41,988,039...41,992,270

G

trefoil factor 2

disease_progression

ISO

protein:increased expression:plasma

NCBI chr21:28,653,077...28,657,709
Ensembl chr21:41,973,111...41,977,227

G

trefoil factor 3

disease_progression

ISO

protein:increased expression:plasma

NCBI chr21:28,627,191...28,631,341
Ensembl chr21:41,948,696...41,952,268

G

transferrin receptor

ISO

protein:increased expression:serum

NCBI chr 3:193,384,817...193,417,532
Ensembl chr 3:203,333,953...203,373,998

G

thyroglobulin

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 8:129,519,431...129,789,699
Ensembl chr 8:132,495,516...132,764,918

G

transforming growth factor beta 1

ISO

protein:increased expression:prostate gland

NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973

G

transforming growth factor beta receptor 2

ISO

OMIM:176807 | OMIM:300147 | OMIM:300704 | OMIM:601518 | OMIM:602759 | OMIM:608656 | OMIM:608658 | OMIM:609299 | OMIM:609558 | OMIM:610321 | OMIM:610997 | OMIM:611100 | OMIM:611868 | OMIM:611928 | OMIM:611955 | OMIM:611958 | OMIM:611959

NCBI chr 3:30,536,187...30,623,653
Ensembl chr 3:30,854,460...30,938,856

G

transforming growth factor beta receptor 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:94,337,275...94,539,229
Ensembl chr 1:93,080,452...93,285,587

G

thrombospondin 1

ISO

mRNA:decreased expression:prostate gland

NCBI chr15:18,521,802...18,538,172
Ensembl chr15:36,776,756...36,793,170

G

thrombospondin 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:130,540,486...130,553,534
Ensembl chr 1:134,148,468...134,160,245

G

thyroid hormone receptor beta

ISO

DNA:loss of heterozygosity (human)

NCBI chr 3:24,024,025...24,401,024
Ensembl chr 3:24,346,824...24,564,960

G

TIMP metallopeptidase inhibitor 2

disease_progression

ISO

DNA, protein:hypermethylation, decreased expression:promoter, prostate gland
protein:increased expression:prostate gland

PMID:17325663 PMID:18329693

RGD:2290389 RGD:2290397

NCBI chr17:72,928,692...73,001,892
Ensembl chr17:78,476,807...78,495,649

G

TIMP metallopeptidase inhibitor 3

disease_progression

ISO

mRNA:decreased expression:prostate gland

NCBI chr22:13,811,297...13,872,799
Ensembl chr22:31,662,562...31,723,964

G

TLE family member 5, transcriptional modulator

ISO

associated with metastasis;protein:decreased expression:prostate

NCBI chr19:2,078,933...2,089,117
Ensembl chr19:3,030,550...3,040,375

G

toll like receptor 2

susceptibility

ISO

DNA:deletion:promoter:−196_−174del (human)

NCBI chr 4:146,024,653...146,091,388
Ensembl chr 4:157,866,977...157,869,331

G

transmembrane and coiled-coil domains 5A

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:16,864,593...16,897,708

G

transmembrane protein with EGF like and two follistatin like domains 2

disease_progression

ISO

DNA:hypermethylation

PMID:15299075 PMID:16458425 PMID:16500022

RGD:2290485 RGD:2290486 RGD:2290490

NCBI chr2B:79,242,825...79,489,113
Ensembl chr2B:197,158,689...197,396,254

G

transmembrane protein 183A

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:178,608,896...178,626,376
Ensembl chr 1:182,903,898...182,919,283

G

transmembrane protein 230

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr20:5,119,775...5,133,079
Ensembl chr20:4,882,980...4,925,869

G

transmembrane protein 94

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:69,407,161...69,449,735
Ensembl chr17:74,972,761...75,000,598

G

tumor necrosis factor

ISO

NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381

G

TNF receptor superfamily member 8

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:10,813,111...10,893,005
Ensembl chr 1:12,029,038...12,108,495

G

DNA topoisomerase II alpha

ISO

NCBI chr17:16,872,169...16,901,605
Ensembl chr17:17,097,778...17,126,207

G

TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:32,314,850...32,327,067
Ensembl chr 9:33,124,730...33,135,129

G

tumor protein p53

disease_progression

ISO

DNA:mutations:exon
ClinVar Annotator: match by term: Malignant tumor of prostate | ClinVar Annotator: match by term: Prostate cancer

PMID:1467311 PMID:1565144 PMID:2750177 PMID:7887414 PMID:7969167 More...

NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120

G

tumor protein p63

ISO

ClinVar Annotator: match by term: Prostate cancer

PMID:23265383 PMID:28492532

NCBI chr 3:186,651,879...186,918,300
Ensembl chr 3:195,199,167...195,474,104

G

tumor protein p73

ISO

mRNA:alternative forms

NCBI chr 1:2,323,399...2,405,295
Ensembl chr 1:3,476,064...3,529,206

G

tripartite motif containing 28

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:55,557,130...55,563,802
Ensembl chr19:64,371,477...64,377,144

G

tripartite motif containing 34

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

G

tripartite motif containing 5

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:5,798,336...5,819,876
Ensembl chr11:5,479,033...5,500,758

G

tripartite motif family like 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:180,294,211...180,302,527
Ensembl chr 4:192,483,189...192,491,414

G

thyroid hormone receptor interactor 12

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr2B:117,013,343...117,175,296
Ensembl chr2B:235,820,182...235,979,780

G

transient receptor potential cation channel subfamily C member 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:139,757,408...139,841,006
Ensembl chr 3:147,349,056...147,432,332

G

transient receptor potential cation channel subfamily C member 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr13:18,852,991...19,081,790
Ensembl chr13:37,445,015...37,592,115

G

transient receptor potential cation channel subfamily M member 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 9:53,367,505...54,272,917
Ensembl chr 9:69,292,593...69,606,949

G

transformation/transcription domain associated protein

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:90,845,518...90,981,700
Ensembl chr 7:104,351,320...104,486,722

G

tumor susceptibility 101

ISO

mRNA:alternative forms:cds:multiple

NCBI chr11:18,518,110...18,564,814
Ensembl chr11:18,189,868...18,248,149

G

teashirt zinc finger homeobox 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:28,195,740...28,270,265
Ensembl chr19:36,946,685...37,021,531

G

translin associated factor X interacting protein 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:48,148,228...48,169,803
Ensembl chr16:67,537,081...67,557,572

G

tetraspanin 5

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:90,872,988...91,052,345
Ensembl chr 4:101,536,950...101,717,228

G

unc-51 like autophagy activating kinase 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:31,262,168...31,362,251
Ensembl chr17:36,409,312...36,507,786

G

uromodulin like 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr21:28,394,457...28,462,082
Ensembl chr21:41,717,761...41,783,172

G

unc-79 homolog, NALCN channel complex subunit

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr14:73,965,908...74,340,573
Ensembl chr14:93,399,547...93,674,248

G

URB2 ribosome biogenesis homolog

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:205,170,805...205,204,644
Ensembl chr 1:210,202,498...210,234,815

G

upstream transcription factor 2, c-fos interacting

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:32,215,305...32,226,172

G

usherin

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:191,193,130...191,994,664
Ensembl chr 1:196,048,086...196,850,216

G

ubiquitin specific peptidase 28

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:108,676,566...108,754,372
Ensembl chr11:112,517,693...112,595,585

G

ubiquitin specific peptidase 48

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:20,870,023...20,974,251
Ensembl chr 1:21,834,638...21,939,250

G

UV radiation resistance associated

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr11:70,870,341...71,197,559
Ensembl chr11:74,172,919...74,496,046

G

versican

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:28492532

NCBI chr 5:31,699,278...31,810,169
Ensembl chr 5:32,019,709...32,130,351

G

voltage dependent anion channel 1

ISO

DNA:SNP: :rs7250897 (human)

NCBI chr 5:129,375,267...129,408,230
Ensembl chr 5:135,529,173...135,560,005

G

vitamin D receptor

susceptibility

ISO

DNA:SNP: :rs11574143 (human)

NCBI chr12:40,828,413...40,891,700
Ensembl chr12:41,702,742...41,766,192

G

vascular endothelial growth factor A

ISO

NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353

G

vitamin K epoxide reductase complex subunit 1 like 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:60,111,428...60,196,412

G

vanin 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:130,521,698...130,535,944
Ensembl chr 6:134,629,464...134,643,934

G

WD repeat and FYVE domain containing 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 4:39,215,474...39,511,870
Ensembl chr 4:45,170,700...45,361,599

G

WD repeat domain 49

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:164,492,444...164,679,218
Ensembl chr 3:172,550,015...172,730,794

G

WAP four-disulfide core domain 1

disease_progression

ISO

mRNA:decreased expression:prostate gland
protein:decreased expression, increased expression:connective tissue, epithelium

PMID:15305341 PMID:15305342

RGD:2291859 RGD:2291860

NCBI chr16:64,958,920...64,994,314
Ensembl chr16:84,301,168...84,333,432

G

WNT inhibitory factor 1

ISO

mRNA, protein:decreased expression:prostate gland

NCBI chr12:23,795,280...23,866,666
Ensembl chr12:24,299,351...24,370,807

G

Wnt family member 2

ISO

mRNA:decreased expression:prostate gland

NCBI chr 7:109,244,772...109,291,472
Ensembl chr 7:121,936,031...121,985,862

G

WWC family member 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr X:2,645,114...2,774,764
Ensembl chr X:9,946,558...10,027,781

G

X-linked inhibitor of apoptosis

disease_progression

ISO

protein:increased expression:prostate gland

PMID:17947468 PMID:19415464

RGD:2315849 RGD:2315852

NCBI chr X:113,052,164...113,105,160
Ensembl chr X:123,232,643...123,278,606

G

X-ray repair cross complementing 1

susceptibility

ISO

DNA:polymorphism: :p.R399Q

NCBI chr19:40,485,052...40,522,188
Ensembl chr19:49,094,014...49,125,520

G

YTH N6-methyladenosine RNA binding protein C2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 5:108,870,417...108,951,848
Ensembl chr 5:114,672,839...114,754,153

G

zDHHC palmitoyltransferase 8

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr22:2,891,738...2,894,404

G

zinc finger homeobox 3

susceptibility

ISO

DNA:deletion (human)
DNA, mRNA:mutations, decreased expression: :multiple, prostate gland (human)

PMID:15750593 PMID:16637072

RGD:2315694 RGD:2315695

NCBI chr16:51,936,471...52,209,695
Ensembl chr16:72,635,666...72,808,360

G

zinc finger with KRAB and SCAN domains 1

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 7:92,050,741...92,080,554
Ensembl chr 7:105,484,185...105,502,895

G

zinc finger matrin-type 3

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 3:176,061,012...176,115,454
Ensembl chr 3:184,128,233...184,288,639

G

zinc finger protein 136

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:11,752,504...11,796,167
Ensembl chr19:12,490,274...12,516,458
Ensembl chr19:12,490,274...12,516,458

G

zinc finger protein 184

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 6:27,284,296...27,307,006
Ensembl chr 6:27,960,728...27,982,907

G

zinc finger protein 224

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:41,048,581...41,063,656
Ensembl chr19:49,658,880...49,669,288

G

zinc finger protein 287

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr17:35,464,681...35,485,619
Ensembl chr2A:110,756,432...110,776,732

G

zinc finger protein 304

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:54,365,820...54,374,436
Ensembl chr19:63,198,736...63,204,914

G

zinc finger protein 419

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:54,499,700...54,506,648
Ensembl chr19:63,330,831...63,336,580

G

zinc finger protein 48

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr16:24,568,986...24,573,671
Ensembl chr16:30,767,036...30,771,400

G

zinc finger protein 534

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:49,382,312...49,393,070

G

zinc finger protein 560

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:8,998,575...9,032,145

G

zinc finger protein 717

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

PMID:23265383 PMID:25741868

NCBI chr 3:75,868,837...75,876,111

G

zinc finger protein 772

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:54,478,907...54,491,409

G

zinc finger protein 776

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr19:54,758,722...54,770,044
Ensembl chr19:63,587,416...63,598,723

G

zona pellucida glycoprotein 4

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr 1:213,435,888...213,444,439
Ensembl chr 1:218,428,967...218,442,383

G

zinc finger and SCAN domain containing 2

ISO

ClinVar Annotator: match by term: Malignant tumor of prostate

NCBI chr15:63,268,141...63,291,499
Ensembl chr15:82,595,450...82,614,776

castration-resistant prostate carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aldo-keto reductase family 1 member C3

ISO

CTD Direct Evidence: marker/mechanism
mRNA,protein:increased expression:epithelial cell:

PMID:23196782 PMID:25555457

NCBI chr10:5,079,580...5,157,572
Ensembl chr10:5,081,214...5,139,812

G

androgen receptor

ISO

CTD Direct Evidence: marker/mechanism

PMID:18985049 PMID:24740322 PMID:28500234 PMID:28757136

NCBI chr X:56,722,828...56,909,004
Ensembl chr X:66,791,081...66,969,357

G

anti-silencing function 1B histone chaperone

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr19:13,685,617...13,702,367
Ensembl chr19:14,411,127...14,428,917

G

cyclin E2

treatment

ISO

NCBI chr 8:91,499,647...91,518,488
Ensembl chr 8:93,702,104...93,717,151

G

CD46 molecule

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 1:183,330,423...183,373,916
Ensembl chr 1:188,031,758...188,182,046

G

centromere protein K

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 5:48,443,491...48,490,999
Ensembl chr 5:50,105,743...50,142,567

G

chromodomain helicase DNA binding protein 1

ISO

DNA:mutations: :

NCBI chr 5:94,165,414...94,238,836
Ensembl chr 5:99,721,032...99,790,263

G

lysine demethylase 1A

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 1:22,205,624...22,269,571
Ensembl chr 1:23,153,066...23,217,692

G

signal transducer and activator of transcription 5A

treatment
disease_progression

ISO

DNA:CNV: :prostate (human)

NCBI chr17:15,005,025...15,029,110
Ensembl chr17:15,228,465...15,251,783

G

NUF2 component of NDC80 kinetochore complex

treatment

ISO

NCBI chr 1:138,743,251...138,777,201
Ensembl chr 1:142,538,420...142,572,364

G

tripartite motif containing 24

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 7:130,420,334...130,547,489
Ensembl chr 7:142,909,009...143,036,526

G

zinc finger protein 217

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr20:49,919,084...49,949,693
Ensembl chr20:51,024,632...51,066,128

G

zinc finger protein 367

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 9:67,483,257...67,515,630
Ensembl chr 9:95,608,140...95,638,326

Familial Prostate Cancer

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adhesion G protein-coupled receptor G1

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr16:37,896,177...37,942,040
Ensembl chr16:57,036,425...57,074,221

G

androgen receptor

ISO

ClinVar Annotator: match by term: Prostate cancer susceptibility

PMID:8530589 PMID:10589774 PMID:11103816 PMID:28492532

NCBI chr X:56,722,828...56,909,004
Ensembl chr X:66,791,081...66,969,357

G

Rho GTPase activating protein 6

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr X:3,767,259...4,291,738
Ensembl chr X:11,058,207...11,582,115

G

alpha tubulin acetyltransferase 1

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 6:30,368,847...30,391,595
Ensembl chr 6:31,238,778...31,261,611

G

ATM serine/threonine kinase

ISO

ClinVar Annotator: match by term: Familial prostate cancer

PMID:15928302 PMID:16941484 PMID:17124347 PMID:17910737 PMID:19431188 More...

NCBI chr11:103,109,979...103,256,405
Ensembl chr11:106,584,228...106,727,041

G

beta-1,3-glucuronyltransferase 1

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr11:129,200,676...129,269,650
Ensembl chr11:133,089,603...133,117,492

G

brain enriched myelin associated protein 1

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr20:50,289,582...50,375,287
Ensembl chr20:51,509,978...51,639,255

G

BCL2 apoptosis regulator

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100

G

BCL2 like 11

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr2A:90,862,070...90,909,833
Ensembl chr2A:112,337,927...112,385,079

G

bridge-like lipid transfer protein family member 3A

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 6:34,356,919...34,439,105
Ensembl chr 6:35,453,735...35,538,846

G

BRCA1 DNA repair associated

ISO

ClinVar Annotator: match by term: Familial prostate cancer

PMID:17319787 PMID:18489799 PMID:20104584 PMID:21203900 PMID:25525159 More...

NCBI chr17:14,197,946...14,279,064
Ensembl chr17:14,428,526...14,506,815

G

BRCA2 DNA repair associated

ISO

ClinVar Annotator: match by term: Familial prostate cancer | ClinVar Annotator: match by term: Hereditary Prostate Cancer | ClinVar Annotator: match by term: Hereditary prostate cancer

PMID:186727 PMID:251866 PMID:8075631 PMID:8524414 PMID:8589730 More...

NCBI chr13:13,574,422...13,658,967
Ensembl chr13:32,010,066...32,091,332

G

chromosome 9 C11orf65 homolog

ISO

ClinVar Annotator: match by term: Familial prostate cancer

PMID:15928302 PMID:16941484 PMID:17124347 PMID:17910737 PMID:19431188 More...

NCBI chr11:103,195,244...103,352,211
Ensembl chr11:106,670,277...106,817,886

G

caspase 8

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr2B:88,490,611...88,542,132
Ensembl chr2B:206,669,544...206,696,468

G

cell division cycle associated 7

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr2B:60,640,994...60,655,158
Ensembl chr2B:178,095,804...178,109,806

G

cadherin 1

ISO

ClinVar Annotator: match by term: Hereditary prostate cancer | ClinVar Annotator: match by term: Prostate cancer susceptibility

PMID:11948460 PMID:14961571 PMID:15235021 PMID:16061854 PMID:16189707 More...

NCBI chr16:49,108,745...49,206,347
Ensembl chr16:68,502,584...68,596,488

G

cyclin dependent kinase inhibitor 1B

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr12:12,742,258...12,747,404
Ensembl chr12:13,120,306...13,125,541

G

chromodomain helicase DNA binding protein 3

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr17:7,919,803...7,947,787
Ensembl chr17:7,910,644...7,933,115

G

checkpoint kinase 2

ISO

ClinVar Annotator: match by term: Familial prostate cancer | ClinVar Annotator: match by term: Hereditary Prostate Cancer | ClinVar Annotator: match by term: Hereditary prostate cancer | ClinVar Annotator: match by term: Prostate cancer susceptibility

PMID:9536098 PMID:10617473 PMID:11053450 PMID:11298456 PMID:11390408 More...

NCBI chr22:9,757,038...9,811,171

G

collagen type XXIII alpha 1 chain

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 5:173,399,146...173,750,380
Ensembl chr 5:180,657,408...181,005,593

G

cytochrome P450 family 3 subfamily A member 4

no_association

ISO

NCBI chr 7:91,797,037...91,824,696
Ensembl chr 7:105,230,666...105,258,401

G

DENN domain containing 4B

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 1:129,286,076...129,303,279
Ensembl chr 1:132,914,514...132,929,906

G

DNA methyltransferase 3 beta

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr20:29,049,993...29,096,957
Ensembl chr20:30,186,069...30,215,487

G

dedicator of cytokinesis 2

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 5:165,000,368...165,447,148
Ensembl chr 5:171,778,952...172,206,238

G

EMSY transcriptional repressor, BRCA2 interacting

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr11:71,496,577...71,604,230

G

fibrosin like 1

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr12:129,837,013...129,936,801

G

HAUS augmin like complex subunit 6

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 9:18,874,901...18,923,393
Ensembl chr 9:19,369,286...19,416,766

G

homeobox B13

ISO

ClinVar Annotator: match by term: Prostate cancer susceptibility

PMID:8756292 PMID:15964834 PMID:17138648 PMID:22236224 PMID:22714738 More...

NCBI chr17:8,807,988...8,810,362
Ensembl chr17:8,994,224...8,996,598

G

inner centromere protein

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr11:57,488,790...57,519,552
Ensembl chr11:60,846,199...60,874,540

G

integrin subunit beta 8

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 7:21,019,917...21,105,143
Ensembl chr 7:20,336,031...20,415,666

G

lysine demethylase 2A

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr11:62,470,549...62,616,135
Ensembl chr11:65,793,464...65,930,498

G

kinetochore scaffold 1

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr15:19,539,264...19,609,593
Ensembl chr15:37,801,705...37,860,858

G

La ribonucleoprotein 4B

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr10:842,621...966,106
Ensembl chr10:894,957...971,154

G

HLA class II histocompatibility antigen, DO alpha chain

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 6:32,573,975...32,579,398
Ensembl chr 6:33,689,171...33,694,576

G

uncharacterized LOC100968114

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr19:28,512,667...28,513,425

G

mitotic arrest deficient 1 like 1

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 7:2,070,299...2,502,471
Ensembl chr 7:2,187,104...2,601,328

G

mitogen-activated protein kinase kinase 1

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr15:45,337,117...45,438,826
Ensembl chr15:63,613,961...63,714,161

G

methyl-CpG binding domain protein 2

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr18:47,534,356...47,609,481

G

muscleblind like splicing regulator 1

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 3:149,288,323...149,487,635
Ensembl chr 3:156,888,763...157,054,207

G

MDS1 and EVI1 complex locus

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 3:166,099,530...166,677,739
Ensembl chr 3:174,154,814...174,731,252

G

matrix metallopeptidase 14

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr14:3,654,125...3,665,158
Ensembl chr14:21,753,305...21,764,058

G

MOB kinase activator 2

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr11:1,502,429...1,573,145
Ensembl chr11:1,528,134...1,545,668

G

mutS homolog 6

ISO

ClinVar Annotator: match by term: Hereditary prostate cancer

PMID:18269114 PMID:24362816 PMID:25741868 PMID:28492532

NCBI chr2A:47,901,591...47,926,662
Ensembl chr2A:48,824,350...48,849,779

G

myosin IXB

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr19:16,563,005...16,700,312

G

nibrin

ISO

ClinVar Annotator: match by term: Hereditary Prostate Cancer

PMID:9590180 PMID:9590181 PMID:9620777 PMID:10398434 PMID:10799436 More...

NCBI chr 8:86,622,797...86,674,202
Ensembl chr 8:88,575,198...88,626,307

G

paired box 9

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr14:17,114,975...17,431,786
Ensembl chr14:35,771,454...35,791,697

G

PBX/knotted 1 homeobox 2

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr11:119,991,916...120,259,800
Ensembl chr11:124,072,715...124,173,865

G

POU class 2 homeobox 2

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr19:38,974,635...39,065,103
Ensembl chr19:47,570,891...47,611,589

G

PPFIA binding protein 2

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr11:7,609,035...7,752,844
Ensembl chr11:7,326,554...7,430,250

G

phosphatase and tensin homolog

ISO

ClinVar Annotator: match by term: Hereditary Prostate Cancer

PMID:12844284 PMID:12938083 PMID:17847000 PMID:21194675 PMID:21956414 More...

NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605

G

Ras association domain family member 3

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr12:24,225,855...24,312,891
Ensembl chr12:24,726,821...24,914,256

G

regulatory factor X7

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr15:35,057,195...35,211,897
Ensembl chr15:53,376,869...53,527,541

G

ribonuclease L

ISO

ClinVar Annotator: match by term: Prostate cancer susceptibility

PMID:12415269 PMID:16609730 PMID:25741868

NCBI chr 1:158,092,346...158,108,026
Ensembl chr 1:161,741,645...161,760,045

G

ring finger protein 43

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr17:52,420,516...52,492,813
Ensembl chr17:57,276,761...57,347,748

G

renalase, FAD dependent amine oxidase

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr10:84,996,999...85,304,240
Ensembl chr10:88,503,683...88,808,990

G

succinyl-CoA:glutarate-CoA transferase

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 7:43,381,156...44,100,614
Ensembl chr 7:43,421,615...44,139,738

G

transcription factor 4

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr18:48,603,069...48,969,010
Ensembl chr18:51,938,357...52,352,030

G

transcription factor 7 like 2

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr10:109,541,524...109,759,499
Ensembl chr10:112,978,167...113,192,281

G

torsin family 1 member A

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 9:100,940,554...100,951,726

G

teashirt zinc finger homeobox 1

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr18:68,597,354...68,676,462
Ensembl chr18:71,873,594...71,951,654

G

tetratricopeptide repeat domain 28

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr22:9,030,021...9,749,142
Ensembl chr22:26,753,335...26,941,509

prostate adenocarcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adiponectin, C1Q and collagen domain containing

susceptibility

ISO

DNA:SNPs, haplotypes:5' utr, introns, exon:multiple

NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885

G

adiponectin receptor 1

susceptibility

ISO

DNA:SNPs, haplotype:intron, exon: (rs12733285, rs7539452) (human)

NCBI chr 1:178,542,496...178,560,055
Ensembl chr 1:182,837,589...182,854,782

G

AKT serine/threonine kinase 1

treatment

ISO

NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756

G

AKT serine/threonine kinase 2

treatment

ISO

NCBI chr19:37,275,799...37,331,971
Ensembl chr19:45,791,800...45,840,271

G

AKT serine/threonine kinase 3

treatment

ISO

NCBI chr 1:219,107,482...219,463,140
Ensembl chr 1:224,480,784...224,824,838

G

androgen receptor

treatment

ISO

NCBI chr X:56,722,828...56,909,004
Ensembl chr X:66,791,081...66,969,357

G

bridging integrator 1

ISO

NCBI chr2B:33,168,767...33,228,075
Ensembl chr2B:127,716,550...127,775,378

G

baculoviral IAP repeat containing 6

ameliorates

ISO

mRNA:increased expression:prostate gland (human)

NCBI chr2A:32,373,479...32,633,088
Ensembl chr2A:33,084,929...33,343,245

G

baculoviral IAP repeat containing 7

exacerbates

ISO

mRNALincreased expression:prostate gland (human)

NCBI chr20:59,618,530...59,623,612
Ensembl chr20:61,157,302...61,161,932

G

B-Raf proto-oncogene, serine/threonine kinase

ISO

NCBI chr 7:132,651,908...132,855,422
Ensembl chr 7:145,138,510...145,327,115

G

calcium/calmodulin dependent protein kinase II inhibitor 1

treatment

ISO

NCBI chr 1:19,437,761...19,441,573
Ensembl chr 1:20,479,562...20,482,600

G

cyclin B1

severity

ISO

NCBI chr 5:44,826,103...44,836,832
Ensembl chr 5:46,394,362...46,405,332

G

cyclin E2

ISO

NCBI chr 8:91,499,647...91,518,488
Ensembl chr 8:93,702,104...93,717,151

G

CD9 molecule

disease_progression

ISO

DNA, mRNA:deletion, point mutation, decreased expression:prostate gland

NCBI chr12:6,327,783...6,366,083
Ensembl chr12:6,245,348...6,283,385

G

chromodomain helicase DNA binding protein 4

ISO

mRNA:decreased expression:prostate gland (human)

NCBI chr12:6,701,004...6,738,621
Ensembl chr12:6,619,089...6,656,076

G

component of inhibitor of nuclear factor kappa B kinase complex

treatment

ISO

NCBI chr10:96,794,228...96,835,449
Ensembl chr10:100,280,490...100,316,918

G

clusterin

treatment

ISO

NCBI chr 8:26,867,973...26,884,838
Ensembl chr 8:24,070,053...24,083,523

G

cAMP responsive element binding protein 3 like 4

ISO

PMID:11830526 PMID:17270658

RGD:13504714 RGD:13504715

NCBI chr 1:129,324,479...129,331,204
Ensembl chr 1:132,953,062...132,959,696

G

catenin beta 1

ISO

ClinVar Annotator: match by term: Prostate adenocarcinoma

PMID:10192393 PMID:25741868 PMID:26619011

NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030

G

DNA methyltransferase 1

ISO

mRNA,protein:increased expression:prostate gland:

NCBI chr19:9,681,847...9,745,334
Ensembl chr19:10,342,478...10,406,972

G

DNA methyltransferase 3 alpha

ISO

mRNA:increased expression:prostate gland:

NCBI chr2A:25,229,593...25,344,733
Ensembl chr2A:25,331,095...25,412,605

G

DNA methyltransferase 3 beta

ISO

mRNA,protein:increased expression:prostate gland:

NCBI chr20:29,049,993...29,096,957
Ensembl chr20:30,186,069...30,215,487

G

fibroblast growth factor 2

disease_progression

ISO

NCBI chr 4:115,005,136...115,076,369
Ensembl chr 4:126,149,813...126,214,942

G

fibroblast growth factor receptor 1

ISO

PMID:18068632 PMID:23576558

RGD:13504748 RGD:2298702

NCBI chr 8:37,713,133...37,773,098
Ensembl chr 8:34,890,147...34,948,904

G

growth factor receptor bound protein 2

ISO

NCBI chr17:69,265,307...69,352,835
Ensembl chr17:74,817,471...74,903,796

G

HRas proto-oncogene, GTPase

ISO

ClinVar Annotator: match by term: Adenocarcinoma of prostate | ClinVar Annotator: match by term: Prostate adenocarcinoma

PMID:1904555 PMID:3510078 PMID:11150980 PMID:16155195 PMID:16170316 More...

NCBI chr11:537,488...540,810
Ensembl chr11:568,305...571,078

G

isocitrate dehydrogenase (NADP(+)) 1

ISO

ClinVar Annotator: match by term: Prostate adenocarcinoma

PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20946881 More...

NCBI chr2B:95,475,320...95,494,286
Ensembl chr2B:213,599,036...213,617,175

G

insulin like growth factor 1 receptor

treatment
disease_progression

ISO

PMID:8692980 PMID:25442907 PMID:25862373 PMID:26452103

RGD:13504753 RGD:13504767 RGD:13504768 RGD:13504771

NCBI chr15:77,332,926...77,648,474
Ensembl chr15:96,535,164...96,832,974

G

inhibitor of nuclear factor kappa B kinase subunit beta

treatment

ISO

NCBI chr 8:41,515,613...41,576,229
Ensembl chr 8:38,960,594...39,020,971

G

integrin linked kinase

disease_progression

ISO

protein:increased expression:tumor: high-grade tumors versus adjacent BHP (P<0.001), BHP from cancer-free patients (P<0.002), or low-grade tumors (P=0.003), also associated with proliferative index (P=0.001), but inversely related to 5-year survival (p=0.004)

NCBI chr11:6,735,735...6,742,922
Ensembl chr11:6,418,717...6,425,788

G

insulin receptor

treatment

ISO

NCBI chr19:6,393,407...6,578,234
Ensembl chr19:7,260,246...7,414,889

G

Jun proto-oncogene, AP-1 transcription factor subunit

disease_progression

ISO

protein:increased expression, increased activation:significantly higher levels in invading vs organ-confined specimens (P<0.001)

NCBI chr 1:58,042,794...58,045,536

G

kinase insert domain receptor

ISO

protein:increased expression:prostate gland
protein:increased expression:tumor:relative to benign prostatic hypertrophy (BPH) tissue

PMID:17491265 PMID:20808233

RGD:2291925 RGD:5684541

NCBI chr 4:68,813,894...68,861,018
Ensembl chr 4:75,377,375...75,427,109

G

mitogen-activated protein kinase kinase 1

disease_progression

ISO

metastasis; inhibition reduced invasiveness of prostate tumor cells

NCBI chr15:45,337,117...45,438,826
Ensembl chr15:63,613,961...63,714,161

G

mitogen-activated protein kinase 1

treatment

ISO

PMID:22139534 PMID:28492138

RGD:13504818 RGD:13504820

NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335

G

MYC proto-oncogene, bHLH transcription factor

ISO

human gene in mouse model

PMID:14522256 PMID:20195545

RGD:7207413 RGD:7207781

NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863

G

nuclear receptor coactivator 2

ameliorates

ISO

human cells in mouse model

NCBI chr 8:66,632,139...66,929,526
Ensembl chr 8:68,293,018...68,400,479

G

NFKB inhibitor alpha

severity

ISO

protein:increased serine phosphorylation

PMID:15073126 PMID:15712212

RGD:13506768 RGD:2298768

NCBI chr14:16,155,331...16,158,588

G

peptidylglycine alpha-amidating monooxygenase

ISO

mRNA:increased expression:prostate gland (human)

NCBI chr 5:98,104,058...98,385,157
Ensembl chr 5:103,913,456...104,085,774

G

platelet derived growth factor subunit A

ISO

protein:increased expression:prostate

NCBI chr 7:648,722...672,023

G

platelet derived growth factor receptor alpha

ISO

protein:increased expression:prostate

NCBI chr 4:69,639,081...69,709,870
Ensembl chr 4:76,199,382...76,271,097

G

3-phosphoinositide dependent protein kinase 1

treatment

ISO

NCBI chr16:1,394,447...1,463,735

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

ISO

ClinVar Annotator: match by term: Adenocarcinoma of prostate

PMID:15016963 PMID:15254419 PMID:15647370 PMID:15805248 PMID:18676830 More...

NCBI chr 3:176,182,765...176,272,024
Ensembl chr 3:184,355,785...184,441,977

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

treatment

ISO

NCBI chr 3:135,685,120...135,867,096
Ensembl chr 3:143,288,563...143,431,314

G

protein kinase C theta

ISO

mRNA:increased expression:prostate

NCBI chr10:6,458,138...6,610,781
Ensembl chr10:6,440,316...6,593,900

G

Raf-1 proto-oncogene, serine/threonine kinase

treatment

ISO

NCBI chr 3:12,510,084...12,590,598
Ensembl chr 3:12,853,415...12,932,871

G

RELA proto-oncogene, NF-kB subunit

disease_progression

ISO

protein:increased expression:prostate gland

PMID:15073126 PMID:15712212

RGD:13506768 RGD:2298768

NCBI chr11:61,012,839...61,022,225
Ensembl chr11:64,347,859...64,356,868

G

signal transducer and activator of transcription 1

disease_progression

ISO

protein:increased activity:prostate

NCBI chr2B:78,270,642...78,316,074
Ensembl chr2B:196,186,906...196,232,280

G

telomerase reverse transcriptase

treatment

ISO

Ensembl chr 5:1,300,960...1,338,872

G

transmembrane serine protease 2

disease_progression

ISO

protein:increased expression, altered localization:prostate gland

NCBI chr21:27,800,466...27,843,395
Ensembl chr21:41,131,515...41,161,088

G

tumor protein p53

ISO

ClinVar Annotator: match by term: Prostate adenocarcinoma
ClinVar Annotator: match by term: Adenocarcinoma of prostate

PMID:1565143 PMID:1565144 PMID:11370630 PMID:12826609 PMID:19468865 More...

NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120

Prostate Cancer, Hereditary, 1

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

B-Raf proto-oncogene, serine/threonine kinase

ISO

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

PMID:12068308 PMID:15035987 PMID:16439621 PMID:17096326 PMID:17119447 More...

NCBI chr 7:132,651,908...132,855,422
Ensembl chr 7:145,138,510...145,327,115

G

homeobox B13

ISO

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

PMID:9536098 PMID:17576681 PMID:25741868 PMID:26467025 PMID:28492532

NCBI chr17:8,807,988...8,810,362
Ensembl chr17:8,994,224...8,996,598

G

HRas proto-oncogene, GTPase

ISO

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

NCBI chr11:537,488...540,810
Ensembl chr11:568,305...571,078

G

KRAS proto-oncogene, GTPase

ISO

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

PMID:17056636 PMID:17468812 PMID:17704260 PMID:18386799 PMID:20949621 More...

NCBI chr12:61,062,689...61,108,524
Ensembl chr12:63,679,293...63,724,335

G

leucine rich repeat containing 56

ISO

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

NCBI chr11:514,227...559,838
Ensembl chr11:575,495...588,750

G

NRAS proto-oncogene, GTPase

ISO

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

NCBI chr 1:87,837,146...87,850,013
Ensembl chr 1:122,890,505...122,903,585

G

phosphatase and tensin homolog

ISO

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

PMID:9467011 PMID:9600246 PMID:10051160 PMID:12786840 PMID:16773562 More...

NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605

G

ribonuclease L

ISO

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1 | ClinVar Annotator: match by term: RNASEL-related condition

PMID:11799394 PMID:12415269 PMID:16609730 PMID:25741868 PMID:28492532

NCBI chr 1:158,092,346...158,108,026
Ensembl chr 1:161,741,645...161,760,045

G

tumor protein p53

ISO

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

PMID:12826609 PMID:20522432 PMID:25741868 PMID:27545002 PMID:28492532 More...

NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120

G

vascular endothelial growth factor A

ISO

ClinVar Annotator: match by term: Prostate cancer, hereditary, 1

NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353

Prostate Cancer, Hereditary, 12

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

EH domain binding protein 1

ISO

ClinVar Annotator: match by term: EHBP1-related condition | ClinVar Annotator: match by term: Prostate cancer, hereditary, 12

PMID:18264098 PMID:25741868

NCBI chr2A:62,784,756...63,122,396
Ensembl chr2A:63,882,029...64,250,914

Prostate Cancer, Hereditary, 13

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

microseminoprotein beta

ISO

ClinVar Annotator: match by term: Prostate cancer, hereditary, 13

PMID:18264096 PMID:18264097 PMID:19153072 PMID:19383797 PMID:19644707

NCBI chr10:43,187,155...43,200,150
Ensembl chr10:46,449,079...46,464,007

Prostate Cancer, Hereditary, 2

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

elaC ribonuclease Z 2

ISO

ClinVar Annotator: match by term: ELAC2-related condition | ClinVar Annotator: match by term: Prostate cancer, hereditary, 2

PMID:10986046 PMID:11175785 PMID:11254448 PMID:11507049 PMID:12515253 More...

NCBI chr17:38,631,454...38,657,855
Ensembl chr17:43,331,453...43,357,241

Prostate Cancer, Hereditary, 9

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

homeobox B13

ISO

ClinVar Annotator: match by term: HOXB13-related condition | ClinVar Annotator: match by term: Prostate cancer, hereditary, 9

PMID:8756292 PMID:15964834 PMID:17138648 PMID:22236224 PMID:22714738 More...

NCBI chr17:8,807,988...8,810,362
Ensembl chr17:8,994,224...8,996,598

Prostate Cancer, Hereditary, X-Linked 3

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

androgen receptor

ISO

ClinVar Annotator: match by term: Prostate cancer, hereditary, X-linked 3

PMID:17970778 PMID:23637914 PMID:25741868 PMID:27899157 PMID:28492532 More...

NCBI chr X:56,722,828...56,909,004
Ensembl chr X:66,791,081...66,969,357

Prostate Cancer, Somatic

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

androgen receptor

ISO

ClinVar Annotator: match by term: Prostate cancer, somatic

PMID:1631125 PMID:1779964 PMID:6541981 PMID:7723794 PMID:7795646 More...

NCBI chr X:56,722,828...56,909,004
Ensembl chr X:66,791,081...66,969,357

G

checkpoint kinase 2

ISO

ClinVar Annotator: match by term: Prostate cancer, somatic

PMID:12533788 PMID:16835864 PMID:16941491 PMID:18058223 PMID:18996005 More...

NCBI chr22:9,757,038...9,811,171

G

KLF transcription factor 6

ISO

ClinVar Annotator: match by term: Prostate cancer, somatic

NCBI chr10:3,781,797...3,790,539
Ensembl chr10:3,789,893...3,796,379

G

mitotic arrest deficient 1 like 1

ISO

ClinVar Annotator: match by term: Prostate cancer, somatic

PMID:11423979 PMID:25741868

NCBI chr 7:2,070,299...2,502,471
Ensembl chr 7:2,187,104...2,601,328

G

phosphatase and tensin homolog

ISO

ClinVar Annotator: match by term: Prostate cancer, somatic

NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605

G

zinc finger homeobox 3

ISO

ClinVar Annotator: match by term: Prostate cancer, somatic

NCBI chr16:51,936,471...52,209,695
Ensembl chr16:72,635,666...72,808,360

Prostate Cancer/Brain Cancer Susceptibility

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

EPH receptor B2

susceptibility

ISO

ClinVar Annotator: match by term: Prostate cancer/brain cancer susceptibility

PMID:15300251 PMID:16155194 PMID:25741868 PMID:28492532

NCBI chr 1:21,895,961...22,107,649
Ensembl chr 1:22,912,570...23,047,118

prostate carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

AKT serine/threonine kinase 2

treatment

ISO

NCBI chr19:37,275,799...37,331,971
Ensembl chr19:45,791,800...45,840,271

G

angiopoietin 1

ISO

protein:increased expression:prostate gland

NCBI chr 8:103,893,234...104,137,661
Ensembl chr 8:106,042,041...106,286,783

G

activating transcription factor 4

treatment

ISO

NCBI chr22:20,426,743...20,428,892
Ensembl chr22:38,248,094...38,249,249

G

BCL2 associated agonist of cell death

ISO

protein:increased expression:prostate gland

NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257

G

BCL2 associated X, apoptosis regulator

disease_progression

ISO

protein:increased expression:prostate gland epithelium

NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468

G

BCL2 like 1

ISO

NCBI chr20:27,955,688...28,015,950
Ensembl chr20:29,088,055...29,146,585

G

BCL2 like 14

ISO

mRNA:decreased expression:prostate gland

NCBI chr12:12,072,021...12,122,015
Ensembl chr12:12,444,839...12,492,777

G

bone morphogenetic protein 2

disease_progression

ISO

protein:increased expression:prostate gland

NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610

G

bone morphogenetic protein 4

disease_progression

ISO

protein:increased expression:prostate

NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752

G

caspase 6

ISO

mRNA:increased expression:prostate gland

NCBI chr 4:102,186,215...102,201,992
Ensembl chr 4:112,753,988...112,768,836

G

cyclin dependent kinase 13

ameliorates

ISO

NCBI chr 7:44,138,345...44,285,606
Ensembl chr 7:44,177,204...44,324,683

G

glycoprotein hormones, alpha polypeptide

ISO

mRNA:increased expression:prostate gland

NCBI chr 6:84,962,974...84,972,638
Ensembl chr 6:88,236,206...88,247,300

G

chitinase 3 like 1

severity

ISO

protein:increased secretion:serum (human)

NCBI chr 1:178,778,081...178,789,704
Ensembl chr 1:183,075,312...183,083,229

G

CRK like proto-oncogene, adaptor protein

ISO

protein:decreased tyrosine phosphorylation:prostate gland

NCBI chr22:3,141,147...3,177,448
Ensembl chr22:19,632,359...19,668,858

G

E2F transcription factor 5

ameliorates

ISO

NCBI chr 8:81,703,423...81,739,827
Ensembl chr 8:83,314,176...83,350,220

G

eukaryotic translation initiation factor 3 subunit H

ISO

DNA:amplification

NCBI chr 8:113,320,059...113,440,769
Ensembl chr 8:115,863,490...115,973,872

G

growth hormone releasing hormone

ISO

mRNA:increased expression:prostate

NCBI chr20:33,573,001...33,583,699
Ensembl chr20:34,687,587...34,693,240

G

histone deacetylase 2

disease_progression

ISO

protein:increased expression:prostate gland

NCBI chr 6:111,731,139...111,761,826
Ensembl chr 6:115,802,367...115,833,004

G

histone deacetylase 3

ISO

protein:increased expression:prostate gland

NCBI chr 5:136,981,790...136,997,786
Ensembl chr 5:143,094,406...143,110,322

G

hydroxymethylbilane synthase

ISO

mRNA:decreased expression:tumor:in matched malignant and non-malignant sample pairs (p = 0.009)

NCBI chr11:113,923,004...113,931,732
Ensembl chr11:117,852,295...117,860,757

G

insulin like growth factor 1 receptor

ISO

NCBI chr15:77,332,926...77,648,474
Ensembl chr15:96,535,164...96,832,974

G

inhibin subunit alpha

ISO

DNA:hypermethylation,loss of heterozygosity:promoter,genomic region:significant hypermethylation (P<0.001) in tumors vs nonmalignant controls, LOH at 2q32-36 in 42% of cases

NCBI chr2B:106,828,948...106,832,993
Ensembl chr2B:225,419,176...225,423,386

G

Jun proto-oncogene, AP-1 transcription factor subunit

ISO

protein:increased activation:tumor:nuclear localization in 13/16 (81.25%) of BPH and 31/36 (86.1%) of adenocarcinomas (PCa) with significantly stronger staining in PCa (P=0.006)

NCBI chr 1:58,042,794...58,045,536

G

zinc-alpha-2-glycoprotein

exacerbates

ISO

NCBI chr 7:91,999,717...92,009,066
Ensembl chr 7:105,432,782...105,442,219

G

MET proto-oncogene, receptor tyrosine kinase

disease_progression

ISO

protein:increased expression:primary tumor, metastatic carcinoma (human)

NCBI chr 7:108,646,278...108,772,238
Ensembl chr 7:121,365,438...121,468,159

G

matrix Gla protein

ISO

mRNA:increased expression:primary tumor; mRNA:decreased expression:metastatic tissue:decreased or absent expression in metastases and cell lines from metastatic tumors

NCBI chr12:14,887,806...14,891,796
Ensembl chr12:15,284,883...15,288,523

G

marker of proliferation Ki-67

ISO

NCBI chr10:124,684,336...124,714,143
Ensembl chr10:128,936,037...128,962,555

G

matrix metallopeptidase 7

ISO

NCBI chr11:97,467,037...97,477,305
Ensembl chr11:100,960,032...100,971,099

G

NME/NM23 nucleoside diphosphate kinase 1

ISO

NCBI chr17:45,243,588...45,252,135
Ensembl chr17:50,113,622...50,131,636

G

platelet derived growth factor subunit B

ISO

NCBI chr22:20,127,223...20,148,407
Ensembl chr22:37,944,018...37,964,883

G

platelet derived growth factor D

disease_progression

ISO

NCBI chr11:98,852,652...99,110,147
Ensembl chr11:102,357,079...102,593,273

G

polo like kinase 1

ISO

mRNA, protein:increased expression:prostate gland

NCBI chr16:14,420,972...14,432,821
Ensembl chr16:23,928,773...23,940,779

G

protein kinase C alpha

ISO

NCBI chr17:60,246,485...60,747,158
Ensembl chr17:65,454,907...65,947,903

G

seryl-tRNA synthetase 1

ISO

mRNA:decreased expression:prostate gland (human)

NCBI chr 1:111,590,850...111,615,068
Ensembl chr 1:110,755,054...110,779,704

G

S-phase kinase associated protein 2

ISO

NCBI chr 5:74,179,608...74,211,563
Ensembl chr 5:79,461,018...79,492,311

G

serine peptidase inhibitor, Kunitz type 1

disease_progression

ISO

protein:decreased expression:prostate gland (human)

NCBI chr15:19,786,621...19,800,297
Ensembl chr15:38,036,638...38,050,303

G

secreted phosphoprotein 1

ISO

NCBI chr 4:80,263,711...80,271,466
Ensembl chr 4:90,988,200...90,995,935

G

signal transducer and activator of transcription 3

ISO

protein:increased activity:prostate gland

PMID:11987152 PMID:18210874

RGD:2291910 RGD:2298538

NCBI chr17:14,928,689...15,003,644
Ensembl chr17:15,152,358...15,227,067

G

signal transducer and activator of transcription 6

ISO

protein:increased activity:tumor:significant increase in constitutive activation vs adjacent normal tissue and unrelated normal prostate, by EMSA

Ensembl chr12:32,068,679...32,085,099

G

transmembrane BAX inhibitor motif containing 6

ISO

mRNA:increased expression:prostate gland

NCBI chr12:38,986,844...39,010,307
Ensembl chr12:39,879,951...39,902,303

G

tumor protein p73

disease_progression

ISO

mRNA, protein:increased expression:prostate gland

NCBI chr 1:2,323,399...2,405,295
Ensembl chr 1:3,476,064...3,529,206

prostate carcinoma in situ

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha-methylacyl-CoA racemase

disease_progression

ISO

NCBI chr 5:76,336,631...76,358,724
Ensembl chr 5:81,687,891...81,742,003

G

angiogenin

ISO

NCBI chr14:1,548,693...1,558,528
Ensembl chr14:19,614,950...19,615,393

G

apurinic/apyrimidinic endodeoxyribonuclease 1

ISO

protein:increased expression, altered localization:prostate, cytoplasm

NCBI chr14:1,329,745...1,332,315
Ensembl chr14:19,381,911...19,384,542

G

androgen receptor

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr X:56,722,828...56,909,004
Ensembl chr X:66,791,081...66,969,357

G

amphiregulin

ISO

protein:increased expression:prostate gland

NCBI chr 4:49,737,191...49,747,013
Ensembl chr 4:55,570,299...55,580,142

G

ATM serine/threonine kinase

ISO

protein:increased serine phosphorylation:prostate gland

NCBI chr11:103,109,979...103,256,405
Ensembl chr11:106,584,228...106,727,041

G

aurora kinase A

ISO

protein:increased expression:prostate gland

PMID:15754349 PMID:16707419

RGD:2293877 RGD:2293883

NCBI chr20:52,707,757...52,730,579
Ensembl chr20:53,994,881...54,017,339

G

aurora kinase B

ISO

NCBI chr17:43,447,661...43,453,864
Ensembl chr17:48,180,066...48,186,129

G

BTG anti-proliferation factor 2

ISO

protein:decreased expression:prostate gland

NCBI chr 1:178,907,317...178,911,410
Ensembl chr 1:183,201,297...183,205,404

G

coactivator associated arginine methyltransferase 1

ISO

protein:increased expression:prostate gland

NCBI chr19:10,424,993...10,476,702
Ensembl chr19:11,144,733...11,195,948

G

cyclin D1

ISO

mRNA, protein:decreased expression:prostate gland

NCBI chr11:64,737,006...64,750,353

G

cyclin E1

ISO

mRNA, protein:increased expression:prostate gland

NCBI chr19:26,739,285...26,751,630
Ensembl chr19:35,496,700...35,510,295

G

cadherin 1

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr16:49,108,745...49,206,347
Ensembl chr16:68,502,584...68,596,488

G

cyclin dependent kinase inhibitor 1B

ISO

CTD Direct Evidence: therapeutic

PMID:18691549 PMID:20932324

NCBI chr12:12,742,258...12,747,404
Ensembl chr12:13,120,306...13,125,541

G

cAMP responsive element binding protein 3 like 4

severity

ISO

NCBI chr 1:129,324,479...129,331,204
Ensembl chr 1:132,953,062...132,959,696

G

colony stimulating factor 1 receptor

ISO

protein:increased expression:prostate gland

NCBI chr 5:145,478,725...145,537,858
Ensembl chr 5:151,483,572...151,517,415

G

cytochrome P450 family 19 subfamily A member 1

ISO

NCBI chr15:30,152,924...30,282,854
Ensembl chr15:48,486,688...48,521,554

G

DNA methyltransferase 1

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr19:9,681,847...9,745,334
Ensembl chr19:10,342,478...10,406,972

G

estrogen receptor 1

ISO

CTD Direct Evidence: marker/mechanism

PMID:16220300 PMID:22025007

NCBI chr 6:149,507,599...149,918,523
Ensembl chr 6:154,317,002...154,631,551

G

estrogen receptor 2

treatment

ISO

CTD Direct Evidence: marker/mechanism

PMID:16220300 PMID:22025007

NCBI chr14:44,807,875...44,919,780
Ensembl chr14:63,064,402...63,131,303

G

fibroblast growth factor 6

ISO

protein:increased expression:prostate gland

NCBI chr12:4,543,776...4,555,352
Ensembl chr12:4,466,975...4,478,459

G

fibroblast growth factor 8

ISO

NCBI chr10:98,372,251...98,378,811
Ensembl chr10:101,844,792...101,853,916

G

fibroblast growth factor receptor 1

ISO

NCBI chr 8:37,713,133...37,773,098
Ensembl chr 8:34,890,147...34,948,904

G

fibroblast growth factor receptor 2

ISO

NCBI chr10:118,055,854...118,175,440
Ensembl chr10:121,469,735...121,588,815

G

fms related receptor tyrosine kinase 1

ISO

protein:decreased expression:prostate gland

NCBI chr13:9,584,850...9,779,542

G

frizzled class receptor 4

ISO

protein:increased expression:prostate gland

NCBI chr11:81,973,680...82,007,733
Ensembl chr11:85,611,989...85,616,065

G

glutathione S-transferase pi 1

ISO

CTD Direct Evidence: marker/mechanism

PMID:22581815 PMID:24312188

NCBI chr11:62,942,756...62,945,701
Ensembl chr11:66,253,421...66,256,472

G

histone deacetylase 1

ISO

protein:increased expression:prostate gland

NCBI chr 1:31,578,373...31,619,970
Ensembl chr 1:32,585,791...32,626,410

G

insulin like growth factor 1

ISO

protein:increased expression:prostate gland

NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177

G

KRAS proto-oncogene, GTPase

ISO

NCBI chr12:61,062,689...61,108,524
Ensembl chr12:63,679,293...63,724,335

G

lymphoid enhancer binding factor 1

ISO

NCBI chr 4:100,552,959...100,674,156
Ensembl chr 4:111,125,312...111,245,980

G

metallothionein-2

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr16:36,894,853...36,895,826
Ensembl chr16:56,007,922...56,028,093

G

LDL receptor related protein 1

ISO

protein:increased expression:prostate gland

NCBI chr12:31,713,938...31,799,287
Ensembl chr12:31,966,149...32,051,979

G

mitogen-activated protein kinase kinase 4

disease_progression

ISO

protein:increased expression

NCBI chr17:39,497,105...39,622,331
Ensembl chr17:44,248,857...44,359,909

G

mitogen-activated protein kinase kinase 6

disease_progression

ISO

protein:increased expression

NCBI chr17:63,342,720...63,483,926
Ensembl chr17:68,730,011...68,870,454

G

mitogen-activated protein kinase kinase 7

disease_progression

ISO

protein:increased expression

NCBI chr19:7,205,124...7,215,776
Ensembl chr19:8,057,598...8,066,512

G

MYC proto-oncogene, bHLH transcription factor

ISO

NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863

G

prohibitin 1

ISO

mRNA, protein:increased expression:prostate gland

NCBI chr17:8,189,555...8,200,491
Ensembl chr17:8,175,968...8,186,790

G

Pim-1 proto-oncogene, serine/threonine kinase

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 6:36,730,669...36,735,954

G

serine protease 8

disease_progression

ISO

mRNA, protein:increased expression:prostate gland

NCBI chr16:23,833,127...23,837,466
Ensembl chr16:31,500,225...31,504,623

G

phosphatase and tensin homolog

ISO

CTD Direct Evidence: marker/mechanism

PMID:18268330 PMID:19081794 PMID:22581815

NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605

G

prostaglandin-endoperoxide synthase 2

ISO

protein:altered localization

NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519

G

RELA proto-oncogene, NF-kB subunit

ISO

protein:increased expression:prostate gland

PMID:15570007 PMID:16278667

RGD:2298767 RGD:2298769

NCBI chr11:61,012,839...61,022,225
Ensembl chr11:64,347,859...64,356,868

G

retinoid X receptor alpha

ISO

protein:decreased expression:prostate

NCBI chr 9:105,424,046...105,539,241
Ensembl chr 9:134,082,865...134,144,704

G

solute carrier family 30 member 4

ISO

protein:decreased expression:prostate gland

NCBI chr15:24,425,816...24,469,085
Ensembl chr15:42,758,455...42,798,815

G

SMAD family member 4

ISO

protein:increased expression:prostate gland

NCBI chr18:44,402,112...44,456,779
Ensembl chr18:47,764,568...47,797,359

G

ST14 transmembrane serine protease matriptase

ISO

protein:increased expression:prostate gland

NCBI chr11:125,001,771...125,021,371
Ensembl chr11:128,888,124...128,913,559

G

serine/threonine kinase 11

ISO

Ensembl chr19:1,188,537...1,210,677

G

TIMP metallopeptidase inhibitor 4

ISO

NCBI chr 3:12,079,195...12,087,485
Ensembl chr 3:12,425,429...12,433,192

G

DNA topoisomerase II beta

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr 3:25,499,239...25,566,029
Ensembl chr 3:25,828,879...25,896,912

G

tumor protein p63

ISO

protein:decreased expression:prostate gland
CTD Direct Evidence: marker/mechanism

PMID:17189982 PMID:17982114 PMID:22581815

RGD:2315433 RGD:2315434

NCBI chr 3:186,651,879...186,918,300
Ensembl chr 3:195,199,167...195,474,104

prostate malignant phyllodes tumor

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

kallikrein related peptidase 3

ISO

CTD Direct Evidence: marker/mechanism

NCBI chr19:47,820,320...47,827,868
Ensembl chr19:56,712,305...56,718,123

prostate small cell carcinoma

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

BRCA2 DNA repair associated

ISO

ClinVar Annotator: match by term: Metastatic Prostate Small Cell Carcinoma

PMID:10550133 PMID:10660329 PMID:11597388 PMID:11802209 PMID:15024741 More...

NCBI chr13:13,574,422...13,658,967
Ensembl chr13:32,010,066...32,091,332

Term paths to the root

Path 1
Term	Annotations
disease	15838
disease of anatomical entity	15494
reproductive system disease	3129
reproductive organ cancer	1406
male reproductive organ cancer	833
prostate cancer	829
Familial Prostate Cancer +	71
Prostate Cancer, Somatic	6
Prostate Cancer/Brain Cancer Susceptibility	1
prostate carcinoma +	146
prostate lymphoma	0
prostate malignant phyllodes tumor	1
prostate neuroendocrine neoplasm	0
prostate sarcoma +	0
Path 2
Term	Annotations
disease	15838
disease of anatomical entity	15494
Urogenital Diseases	4922
reproductive system disease	3129
male reproductive system disease	1992
Male Genital Neoplasms	1320
Prostatic Neoplasms	1293
prostate cancer	829
Familial Prostate Cancer +	71
Prostate Cancer, Somatic	6
Prostate Cancer/Brain Cancer Susceptibility	1
prostate carcinoma +	146
prostate lymphoma	0
prostate malignant phyllodes tumor	1
prostate neuroendocrine neoplasm	0
prostate sarcoma +	0

paths to the root