RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
A nonepidermolytic palmoplantar keratoderma characterized by localized areas of hyperkeratosis located mainly on pressure points and sites of recurrent friction. (DO)
Synonyms:
exact_synonym:
FNEPPK; Focal Palmoplantar Keratoderma; Focal non epidermolytic palmoplantar keratoderma; early onset tylosis (type B); familial tylosis; hyperkeratosis of the palms and soles and esophageal papillomas; isolated focal non-epidermolytic palmoplantar keratoderma; late onset tylosis (type A)