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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Parkinsonism
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Accession:DOID:0080855 term browser browse the term
Definition:A movement disorder that is characterized by disturbances of balance, gait and posture. (DO)
Synonyms:exact_synonym: Autosomal Dominant Juvenile Parkinsonism;   Autosomal Dominant Parkinsonism;   Autosomal Recessive Juvenile Parkinson Disease;   Autosomal Recessive Parkinsonism;   Autosomal Recesssive Juvenile Parkinsonism;   Chromosome 6 Linked Autosomal Recessive Parkinsonism;   EPDF;   Experimental Parkinson Disease;   Experimental Parkinsonism;   Familial Juvenile Parkinsonism;   Familial Parkinson Disease, Autosomal Recessive;   Juvenile Parkinson Disease;   Juvenile Parkinsonism;   Juvenile Parkinsonism, Autosomal Recessive;   MPTP Induced Experimental Parkinsonism;   PDJ;   Parkinsonian Disorders;   Parkinsonian Syndrome;   Parkinsonian disorder;   Ramsay Hunt paralysis syndrome;   autosomal dominant juvenile Parkinson disease;   experimental Parkinson diseases;   parkinsonian diseases;   parkinsonian syndromes
 primary_id: MESH:D020734


show annotations for term's descendants           Sort by:
Parkinsonism term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABAT 4-aminobutyrate aminotransferase treatment ISO RGD PMID:22634324 RGD:9588554 NCBI chr16:8,674,617...8,784,570
Ensembl chr16:8,674,596...8,784,575 		JBrowse link
G ABCC8 ATP binding cassette subfamily C member 8 ISO RGD PMID:15857625 RGD:1598645 NCBI chr11:17,392,498...17,476,845
Ensembl chr11:17,392,498...17,476,894 		JBrowse link
G ABCC9 ATP binding cassette subfamily C member 9 ISO RGD PMID:15857625 RGD:1598645 NCBI chr12:21,797,389...21,941,426
Ensembl chr12:21,797,389...21,942,543 		JBrowse link
G ADCYAP1 adenylate cyclase activating polypeptide 1 ISO RGD PMID:16888218 RGD:2325295 NCBI chr18:904,411...912,172
Ensembl chr18:904,871...912,172 		JBrowse link
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25045800 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442 		JBrowse link
G ALDH1A2 aldehyde dehydrogenase 1 family member A2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25045800 NCBI chr15:57,953,429...58,065,711
Ensembl chr15:57,953,424...58,497,866 		JBrowse link
G ANG angiogenin ISO RGD PMID:21091473 RGD:6892711 NCBI chr14:20,684,177...20,694,186
Ensembl chr14:20,684,177...20,698,971 		JBrowse link
G APAF1 apoptotic peptidase activating factor 1 treatment ISO RGD PMID:11535810 RGD:13503334 NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,290...98,735,433 		JBrowse link
G AQP4 aquaporin 4 severity ISO RGD PMID:21255222 RGD:5148006 NCBI chr18:26,852,038...26,865,803
Ensembl chr18:26,852,043...26,865,771 		JBrowse link
G ATP13A2 ATPase cation transporting 13A2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23046578 NCBI chr 1:16,985,958...17,011,928
Ensembl chr 1:16,985,958...17,011,928 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15260953 NCBI chr19:41,966,582...41,994,230
Ensembl chr19:41,966,582...41,997,497 		JBrowse link
G BAD BCL2 associated agonist of cell death ISO RGD PMID:23251488 RGD:10053712 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704 		JBrowse link
G BDNF brain derived neurotrophic factor treatment IDA RGD PMID:16018990 RGD:8657066 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G BECN1 beclin 1 treatment ISO RGD PMID:19864570 PMID:25424835 RGD:6483312, RGD:11558014 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350 		JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:28881616 PMID:27016191 PMID:28338241 RGD:13503337, RGD:13503339, RGD:13503338 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP9 caspase 9 treatment ISO RGD PMID:26612350 RGD:13503344 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CCL4 C-C motif chemokine ligand 4 ISO RGD PMID:17258864 RGD:5683893 NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621 		JBrowse link
G CNR1 cannabinoid receptor 1 ISO RGD PMID:19414037 RGD:2314672 NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,347 		JBrowse link
G COMT catechol-O-methyltransferase ISO RGD PMID:15698633 RGD:2289785 NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975 		JBrowse link
G CSF1R colony stimulating factor 1 receptor IAGP ClinVar Annotator: match by term: Parkinsonism ClinVar PMID:25741868 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372 		JBrowse link
G CSF2 colony stimulating factor 2 ISO RGD PMID:21291297 RGD:5131508 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 ISO RGD PMID:19368990 RGD:4891964 NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044 		JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 ISO RGD PMID:19368990 RGD:4891964 NCBI chr 3:39,263,494...39,292,966
Ensembl chr 3:39,263,495...39,281,735 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO mRNA:decreased expression:striatum RGD PMID:18374908 RGD:5147675 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G DCTN1 dynactin subunit 1 EXP
IAGP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Parkinsonism		 CTD
ClinVar		 PMID:19136952 PMID:25741868 PMID:28492532 PMID:28518168 PMID:29525180 More... NCBI chr 2:74,361,155...74,391,866
Ensembl chr 2:74,361,154...74,392,087 		JBrowse link
G DDC dopa decarboxylase EXP CTD Direct Evidence: therapeutic CTD PMID:16269145 NCBI chr 7:50,458,442...50,565,405
Ensembl chr 7:50,458,436...50,565,405 		JBrowse link
G DRD2 dopamine receptor D2 ISO
EXP		 CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:9171869 PMID:12476322 PMID:15469457 PMID:22126770 RGD:6907448 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691 		JBrowse link
G DRD3 dopamine receptor D3 ISO RGD PMID:12535962 RGD:1358605 NCBI chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407 		JBrowse link
G EGFR epidermal growth factor receptor ISO protein:decreased expression:striatum RGD PMID:15857400 RGD:2289955 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EN1 engrailed homeobox 1 ISO RGD PMID:17015829 RGD:5687199 NCBI chr 2:118,842,171...118,847,648
Ensembl chr 2:118,842,171...118,847,648 		JBrowse link
G EN2 engrailed homeobox 2 ISO RGD PMID:17015829 RGD:5687199 NCBI chr 7:155,458,129...155,464,831
Ensembl chr 7:155,458,129...155,464,831 		JBrowse link
G ENO2 enolase 2 ISO RGD PMID:17532790 RGD:2293747 NCBI chr12:6,914,580...6,923,697
Ensembl chr12:6,913,745...6,923,698 		JBrowse link
G ESR1 estrogen receptor 1 ISO RGD PMID:21420980 RGD:8553241 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G FGF2 fibroblast growth factor 2 treatment IDA RGD PMID:27228974 RGD:13801017 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236 		JBrowse link
G FKBP1A FKBP prolyl isomerase 1A ISO mRNA, protein:increased expression:brain RGD PMID:17877381 RGD:2302074 NCBI chr20:1,368,978...1,393,054
Ensembl chr20:1,368,977...1,393,164 		JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase EXP CTD Direct Evidence: marker/mechanism CTD PMID:29886133 NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374 		JBrowse link
G GBA1 glucosylceramidase beta 1 severity IAGP
EXP		 DNA:missense mutations:cds:multiple (human)
ClinVar Annotator: match by term: Parkinsonism
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
RGD		 PMID:1864608 PMID:1899336 PMID:1972019 PMID:2309702 PMID:2378352 More... RGD:5508426 NCBI chr 1:155,234,452...155,244,627
Ensembl chr 1:155,234,452...155,244,699 		JBrowse link
G GCH1 GTP cyclohydrolase 1 treatment ISO
IMP		 RGD PMID:25592335 PMID:15684695 PMID:12451130 PMID:16708545 PMID:23831692 RGD:329970292, RGD:1580026, RGD:628489, RGD:401700385, RGD:401700381 NCBI chr14:54,842,017...54,902,826
Ensembl chr14:54,842,008...54,902,826 		JBrowse link
G GDNF glial cell derived neurotrophic factor treatment ISO
EXP
IDA		 protein:decreased expression:brain
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:9266731 PMID:12213621 PMID:22186119 PMID:16018990 PMID:21865882 RGD:5686884, RGD:8657066, RGD:6218962 NCBI chr 5:37,812,677...37,840,041
Ensembl chr 5:37,812,677...37,840,041 		JBrowse link
G GFRA1 GDNF family receptor alpha 1 ISO mRNA:altered expression:brain RGD PMID:21865882 PMID:12210101 RGD:6218962, RGD:6218972 NCBI chr10:116,056,925...116,274,705
Ensembl chr10:116,056,925...116,276,803 		JBrowse link
G GFRA2 GDNF family receptor alpha 2 ISO mRNA:decreased expression:brain RGD PMID:12210101 RGD:6218972 NCBI chr 8:21,690,398...21,812,345
Ensembl chr 8:21,690,398...21,812,357 		JBrowse link
G GJA1 gap junction protein alpha 1 treatment ISO RGD PMID:23783886 RGD:8662444 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727 		JBrowse link
G GNAL G protein subunit alpha L ISO RGD PMID:22539851 RGD:13513924 NCBI chr18:11,689,264...11,885,685
Ensembl chr18:11,689,264...11,885,685 		JBrowse link
G GRM8 glutamate metabotropic receptor 8 ISO RGD PMID:22546615 RGD:6771180 NCBI chr 7:126,438,598...127,252,941
Ensembl chr 7:126,438,598...127,253,093 		JBrowse link
G GRN granulin precursor IAGP ClinVar Annotator: match by term: Parkinsonism ClinVar NCBI chr17:44,345,302...44,353,106
Ensembl chr17:44,345,246...44,353,106 		JBrowse link
G GSK3A glycogen synthase kinase 3 alpha ISO protein:decreased expression:striatum RGD PMID:18805403 RGD:10401814 NCBI chr19:42,230,190...42,242,602
Ensembl chr19:42,226,225...42,242,625 		JBrowse link
G GSR glutathione-disulfide reductase treatment ISO
EXP		 CTD Direct Evidence: therapeutic CTD
RGD		 PMID:22721943 PMID:20951685 RGD:5128840 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846 		JBrowse link
G HMOX1 heme oxygenase 1 treatment ISO RGD PMID:24169105 RGD:10755712 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A IMP RGD PMID:15585408 RGD:5147599 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946 		JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 ISO protein:decreased expression:striatum RGD PMID:21542017 RGD:6784518 NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,675 		JBrowse link
G HTRA2 HtrA serine peptidase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26558463 NCBI chr 2:74,529,405...74,533,556
Ensembl chr 2:74,529,596...74,533,350 		JBrowse link
G IL1B interleukin 1 beta ISO protein:increased expression:hypothalamus RGD PMID:17520785 RGD:1626658 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 ISO mRNA, protein:increased expression:prefrontal cortex, striatum, hippocampus (rat) RGD PMID:15857625 RGD:1598645 NCBI chr11:17,385,248...17,389,346
Ensembl chr11:17,365,172...17,389,331 		JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 ISO mRNA, protein:increased expression:striatum, hippocampus (rat) RGD PMID:15857625 RGD:1598645 NCBI chr12:21,764,955...21,774,706
Ensembl chr12:21,764,955...21,775,600 		JBrowse link
G LOC106627981 GBA recombination region IAGP ClinVar Annotator: match by term: Parkinsonism ClinVar PMID:1864608 PMID:1899336 PMID:1972019 PMID:2309702 PMID:2378352 More... NCBI chr 1:155,233,639...155,240,092 JBrowse link
G LOC111188154 RORalpha allelically-responsive CSF1R enhancer IAGP ClinVar Annotator: match by term: Parkinsonism ClinVar PMID:25741868 NCBI chr 5:150,077,995...150,078,215 JBrowse link
G LOC129933272 ATAC-STARR-seq lymphoblastoid active region 15435 IAGP ClinVar Annotator: match by term: Parkinsonism ClinVar PMID:27134041 PMID:27753167
G LRRK2 leucine rich repeat kinase 2 IMP
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:23046578 PMID:25017139 PMID:26558463 PMID:20729864 RGD:5508414 NCBI chr12:40,224,997...40,369,285
Ensembl chr12:40,196,744...40,369,285 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase ISO RGD PMID:16529858 RGD:1581410 NCBI chr 8:55,879,835...56,014,169
Ensembl chr 8:55,879,835...56,014,169 		JBrowse link
G MANF mesencephalic astrocyte derived neurotrophic factor IMP RGD PMID:19641128 RGD:2325813 NCBI chr 3:51,385,291...51,389,397
Ensembl chr 3:51,385,291...51,389,397 		JBrowse link
G MAPT microtubule associated protein tau treatment EXP
IAGP
ISO		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Parkinsonism		 CTD
ClinVar
RGD		 PMID:10802785 PMID:19458322 PMID:27228974 RGD:13801017 NCBI chr17:45,894,554...46,028,334
Ensembl chr17:45,894,527...46,028,334 		JBrowse link
G MMP3 matrix metallopeptidase 3 treatment ISO RGD PMID:22498097 RGD:8693688 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609 		JBrowse link
G MMP9 matrix metallopeptidase 9 treatment ISO RGD PMID:15075439 RGD:13204850 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MT-CO1 mitochondrially encoded cytochrome c oxidase I ISO mRNA:decreased expression:thalamus RGD PMID:17148469 RGD:2302296 NCBI chr MT:5,904...7,445
Ensembl chr MT:5,904...7,445 		JBrowse link
G MTOR mechanistic target of rapamycin kinase treatment ISO RGD PMID:20089925 RGD:10040992 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G NDUFS3 NADH:ubiquinone oxidoreductase core subunit S3 ISO RGD PMID:20403401 RGD:13824972 NCBI chr11:47,579,074...47,584,562
Ensembl chr11:47,565,336...47,584,562 		JBrowse link
G NFKB2 nuclear factor kappa B subunit 2 ISO RGD PMID:18534259 RGD:2302392 NCBI chr10:102,394,110...102,402,529
Ensembl chr10:102,394,110...102,402,524 		JBrowse link
G NGF nerve growth factor EXP CTD Direct Evidence: therapeutic CTD PMID:19694610 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770 		JBrowse link
G NOS1 nitric oxide synthase 1 ISO RGD PMID:23967645 RGD:7257596 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170 		JBrowse link
G NR4A2 nuclear receptor subfamily 4 group A member 2 treatment ISO RGD PMID:31408200 RGD:124713575 NCBI chr 2:156,324,437...156,332,721
Ensembl chr 2:156,324,437...156,342,348 		JBrowse link
G PACRG parkin coregulated IAGP ClinVar Annotator: match by term: Parkinson Disease, Juvenile ClinVar NCBI chr 6:162,727,132...163,315,500
Ensembl chr 6:162,727,132...163,315,500 		JBrowse link
G PARK7 Parkinsonism associated deglycase treatment IMP
IAGP
EXP
ISO		 ClinVar Annotator: match by term: Parkinson Disease, Juvenile
CTD Direct Evidence: marker/mechanism
protein:decreased expression:brain		 ClinVar
CTD
RGD		 PMID:23046578 PMID:26558463 PMID:16860563 PMID:22710069 PMID:18373560 More... RGD:1601076, RGD:13463458, RGD:13463452, RGD:13210569, RGD:13462067 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17640816 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PDE1B phosphodiesterase 1B ISO RGD PMID:15305867 RGD:2312524 NCBI chr12:54,549,601...54,579,239
Ensembl chr12:54,549,601...54,579,239 		JBrowse link
G PDGFRB platelet derived growth factor receptor beta IAGP ClinVar Annotator: match by term: Parkinsonism ClinVar PMID:25741868 NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872 		JBrowse link
G PDYN prodynorphin disease_progression EXP
ISO		 CTD Direct Evidence: marker/mechanism
mRNA:increased expression:striatum		 CTD
RGD		 PMID:9930741 PMID:26113400 RGD:401851054 NCBI chr20:1,978,756...1,994,285
Ensembl chr20:1,978,757...1,994,285 		JBrowse link
G PINK1 PTEN induced kinase 1 ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:11254447 PMID:15349871 PMID:23046578 PMID:24441527 PMID:24792327 More... RGD:13210569 NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511 		JBrowse link
G PNOC prepronociceptin EXP CTD Direct Evidence: marker/mechanism CTD PMID:26687234 NCBI chr 8:28,316,988...28,343,351
Ensembl chr 8:28,316,986...28,343,355 		JBrowse link
G POLG DNA polymerase gamma, catalytic subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:17923349 NCBI chr15:89,316,320...89,334,824
Ensembl chr15:89,305,198...89,334,861 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO RGD PMID:22246294 PMID:21376232 PMID:22040668 RGD:6484262, RGD:6484271, RGD:6484267 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G PRKCD protein kinase C delta EXP CTD Direct Evidence: therapeutic CTD PMID:15681813 NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase IAGP
EXP		 ClinVar Annotator: match by term: Parkinson Disease, Juvenile
ClinVar Annotator: match by term: Juvenile parkinsonism
CTD Direct Evidence: marker/mechanism|therapeutic		 ClinVar
CTD		 PMID:10072423 PMID:10894217 PMID:11254447 PMID:12629236 PMID:12764050 More... NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G PRKRA protein activator of interferon induced protein kinase EIF2AK2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18243799 NCBI chr 2:178,431,414...178,451,175
Ensembl chr 2:178,431,292...178,451,512 		JBrowse link
G PRL prolactin EXP CTD Direct Evidence: marker/mechanism CTD PMID:240179 NCBI chr 6:22,287,246...22,302,835
Ensembl chr 6:22,287,244...22,302,826 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO mRNA, protein:increased expression:neostriatum RGD PMID:21376018 PMID:16781689 PMID:15306248 RGD:5508224, RGD:5688269, RGD:5688225 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTRHD1 peptidyl-tRNA hydrolase domain containing 1 IAGP ClinVar Annotator: match by term: Parkinsonism ClinVar PMID:27134041 PMID:27753167 NCBI chr 2:24,789,728...24,793,391
Ensembl chr 2:24,789,728...24,793,391 		JBrowse link
G RANBP2 RAN binding protein 2 severity ISO RGD PMID:22821000 RGD:9835348 NCBI chr 2:108,719,482...109,842,301
Ensembl chr 2:108,719,482...108,785,810 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO RGD PMID:18534259 RGD:2302392 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RET ret proto-oncogene ISO mRNA:altered expression:brain RGD PMID:12210101 RGD:6218972 NCBI chr10:43,077,069...43,130,351
Ensembl chr10:43,077,064...43,130,351 		JBrowse link
G RGS4 regulator of G protein signaling 4 treatment ISO RGD PMID:25844489 RGD:13524517 NCBI chr 1:163,068,871...163,076,802
Ensembl chr 1:163,068,775...163,076,802 		JBrowse link
G RGS9 regulator of G protein signaling 9 treatment ISO protein:decreased expression:striatum RGD PMID:20561938 PMID:18160641 PMID:21963945 RGD:13524532, RGD:13524864, RGD:13524862 NCBI chr17:65,137,370...65,227,703
Ensembl chr17:65,100,812...65,227,703 		JBrowse link
G SHH sonic hedgehog signaling molecule treatment ISO RGD PMID:25030123 RGD:12859032 NCBI chr 7:155,799,980...155,812,463
Ensembl chr 7:155,799,980...155,812,463 		JBrowse link
G SLC11A2 solute carrier family 11 member 2 ISO RGD PMID:19011085 PMID:20125122 PMID:19011085 RGD:5688713, RGD:5688715, RGD:5688713 NCBI chr12:50,952,263...51,028,886
Ensembl chr12:50,979,401...51,028,566 		JBrowse link
G SLC17A8 solute carrier family 17 member 8 ISO protein:increased expression:substantia nigra pars reticulata, neuron, perikaryon RGD PMID:17435391 RGD:9999153 NCBI chr12:100,357,074...100,422,055
Ensembl chr12:100,357,074...100,422,055 		JBrowse link
G SLC18A2 solute carrier family 18 member A2 EXP CTD Direct Evidence: therapeutic CTD PMID:16269145 NCBI chr10:117,241,114...117,279,430
Ensembl chr10:117,241,093...117,279,430 		JBrowse link
G SLC30A10 solute carrier family 30 member 10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26220508 NCBI chr 1:219,910,445...219,959,098
Ensembl chr 1:219,685,427...219,959,018 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO protein:decreased expression:striatum RGD PMID:15680936 RGD:1625663 NCBI chr 5:1,392,794...1,445,440
Ensembl chr 5:1,392,794...1,445,440 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO RGD PMID:20447560 RGD:4889474 NCBI chr17:30,194,319...30,235,697
Ensembl chr17:30,194,319...30,236,002 		JBrowse link
G SNCA synuclein alpha ISO
EXP		 mRNA:decreased expression:brain
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:20464527 PMID:22319455 PMID:23046578 PMID:23295396 PMID:26075822 More... RGD:6478799, RGD:6478802 NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315 		JBrowse link
G SNCG synuclein gamma ISO RGD PMID:15147505 RGD:6478802 NCBI chr10:86,955,759...86,963,258
Ensembl chr10:86,958,599...86,963,258 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:16529858 RGD:1581410 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050 		JBrowse link
G TBC1D24 TBC1 domain family member 24 IAGP ClinVar Annotator: match by term: Parkinsonism ClinVar PMID:3402014 PMID:25741868 PMID:27541164 PMID:28492532 PMID:28663785 More... NCBI chr16:2,475,127...2,505,730
Ensembl chr16:2,475,051...2,509,560 		JBrowse link
G TFAM transcription factor A, mitochondrial ISO mRNA:increased expression:striatum RGD PMID:22040668 RGD:6484267 NCBI chr10:58,385,410...58,399,220
Ensembl chr10:58,385,345...58,399,220 		JBrowse link
G TGM6 transglutaminase 6 IAGP ClinVar Annotator: match by term: Parkinsonism ClinVar PMID:25741868 NCBI chr20:2,380,901...2,432,753
Ensembl chr20:2,380,901...2,432,753 		JBrowse link
G TH tyrosine hydroxylase susceptibility
treatment		 IAGP
IMP
ISO
EXP		 Segawa syndrome,autosomal recessive, OMIM:605407;DNA:missense mutation:exon:p.Q381L
protein:decreased expression:striatum
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:8817341 PMID:11246459 PMID:7814018 PMID:23831692 PMID:20561938 RGD:1601634, RGD:401700381, RGD:13524532 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815 		JBrowse link
G TNF tumor necrosis factor treatment ISO RGD PMID:21831964 PMID:28338241 RGD:7247422, RGD:13503338 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B treatment IDA RGD PMID:21831964 RGD:7247422 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228 		JBrowse link
G TNFRSF9 TNF receptor superfamily member 9 IAGP ClinVar Annotator: match by term: Parkinson Disease, Juvenile ClinVar NCBI chr 1:7,915,871...7,940,839
Ensembl chr 1:7,915,871...7,943,165 		JBrowse link
G UCN urocortin ISO RGD PMID:21362449 RGD:5508188 NCBI chr 2:27,307,400...27,308,445
Ensembl chr 2:27,307,400...27,308,445 		JBrowse link
G VDAC1 voltage dependent anion channel 1 IEP RGD PMID:24825319 RGD:13504672 NCBI chr 5:133,971,871...134,114,540
Ensembl chr 5:133,971,871...134,004,975 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor ISO RGD PMID:20302395 RGD:2325190 NCBI chr 3:10,141,778...10,153,667
Ensembl chr 3:10,141,778...10,153,667 		JBrowse link
G VIP vasoactive intestinal peptide ISO RGD PMID:15808913 RGD:5685601 NCBI chr 6:152,750,797...152,759,760
Ensembl chr 6:152,750,797...152,759,765 		JBrowse link
amyotrophic lateral sclerosis-parkinsonism/dementia complex 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARK7 Parkinsonism associated deglycase IAGP ClinVar Annotator: match by term: Guam disease ClinVar PMID:25741868 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505 		JBrowse link
G TRPM7 transient receptor potential cation channel subfamily M member 7 susceptibility
no_association		 IAGP
EXP		 DNA:mutation:cds: p.T1482I (human)
ClinVar Annotator: match by term: Guam disease
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM
RGD		 PMID:25741868 PMID:28492532 PMID:16051700 PMID:19405049 RGD:5685005, RGD:5685008 NCBI chr15:50,557,158...50,686,797
Ensembl chr15:50,552,473...50,686,797 		JBrowse link
Autosomal Dominant Diffuse Lewy Body Disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GBA1 glucosylceramidase beta 1 IAGP ClinVar Annotator: match by term: Autosomal dominant diffuse Lewy body disease ClinVar PMID:1348297 PMID:1897529 PMID:1899336 PMID:1971142 PMID:1972019 More... NCBI chr 1:155,234,452...155,244,627
Ensembl chr 1:155,234,452...155,244,699 		JBrowse link
G LOC106627981 GBA recombination region IAGP ClinVar Annotator: match by term: Autosomal dominant diffuse Lewy body disease ClinVar PMID:1348297 PMID:1897529 PMID:1899336 PMID:1971142 PMID:1972019 More... NCBI chr 1:155,233,639...155,240,092 JBrowse link
classic dopamine transporter deficiency syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC6A3 solute carrier family 6 member 3 IAGP ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile, 1 OMIM
ClinVar		 PMID:10889530 PMID:16103889 PMID:16171832 PMID:16199547 PMID:16212992 More... NCBI chr 5:1,392,794...1,445,440
Ensembl chr 5:1,392,794...1,445,440 		JBrowse link
dopamine transporter deficiency syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHRR aryl hydrocarbon receptor repressor IAGP ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile ClinVar PMID:21112253 PMID:28492532 NCBI chr 5:321,714...438,285
Ensembl chr 5:321,714...438,291 		JBrowse link
G BRD9 bromodomain containing 9 IAGP ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile ClinVar PMID:21112253 PMID:28492532 NCBI chr 5:863,741...892,801
Ensembl chr 5:850,291...892,801 		JBrowse link
G CEP72 centrosomal protein 72 IAGP ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile ClinVar PMID:21112253 PMID:28492532 NCBI chr 5:612,340...676,616
Ensembl chr 5:612,340...667,168 		JBrowse link
G CLPTM1L CLPTM1 like IAGP ClinVar Annotator: match by term: Infantile dystonia-parkinsonism
ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile		 ClinVar PMID:21112253 PMID:28492532 NCBI chr 5:1,317,752...1,345,099
Ensembl chr 5:1,317,752...1,345,099 		JBrowse link
G EXOC3 exocyst complex component 3 IAGP ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile ClinVar PMID:21112253 PMID:28492532 NCBI chr 5:443,176...467,290
Ensembl chr 5:443,175...471,937 		JBrowse link
G EXOC3-AS1 EXOC3 antisense RNA 1 IAGP ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile ClinVar PMID:21112253 PMID:28492532 NCBI chr 5:441,835...443,160
Ensembl chr 5:441,498...443,160 		JBrowse link
G IRX4 iroquois homeobox 4 IAGP ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile ClinVar PMID:21112253 PMID:28492532 NCBI chr 5:1,877,413...1,887,179
Ensembl chr 5:1,877,413...1,887,236 		JBrowse link
G LPCAT1 lysophosphatidylcholine acyltransferase 1 IAGP ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile ClinVar PMID:21112253 PMID:28492532 NCBI chr 5:1,461,427...1,523,960
Ensembl chr 5:1,456,480...1,523,962 		JBrowse link
G MRPL36 mitochondrial ribosomal protein L36 IAGP ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile ClinVar PMID:21112253 PMID:28492532 NCBI chr 5:1,798,385...1,801,434
Ensembl chr 5:1,798,385...1,801,366 		JBrowse link
G NDUFS6 NADH:ubiquinone oxidoreductase subunit S6 IAGP ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile ClinVar PMID:21112253 PMID:28492532 NCBI chr 5:1,801,407...1,816,048
Ensembl chr 5:1,801,407...1,816,048 		JBrowse link
G NKD2 NKD inhibitor of WNT signaling pathway 2 IAGP ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile ClinVar PMID:21112253 PMID:28492532 NCBI chr 5:1,008,802...1,038,943
Ensembl chr 5:1,008,802...1,038,943 		JBrowse link
G PDCD6 programmed cell death 6 IAGP ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile ClinVar PMID:21112253 PMID:28492532 NCBI chr 5:271,646...314,974
Ensembl chr 5:271,621...314,974 		JBrowse link
G SDHA succinate dehydrogenase complex flavoprotein subunit A IAGP ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile ClinVar PMID:21112253 PMID:28492532 NCBI chr 5:218,320...268,746
Ensembl chr 5:218,303...257,082 		JBrowse link
G SLC12A7 solute carrier family 12 member 7 IAGP ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile ClinVar PMID:21112253 PMID:28492532 NCBI chr 5:1,050,384...1,155,899
Ensembl chr 5:1,050,384...1,112,063 		JBrowse link
G SLC6A18 solute carrier family 6 member 18 IAGP ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile ClinVar PMID:21112253 PMID:28492532 NCBI chr 5:1,225,381...1,246,189
Ensembl chr 5:1,225,381...1,246,189 		JBrowse link
G SLC6A19 solute carrier family 6 member 19 IAGP ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile ClinVar PMID:21112253 PMID:28492532 NCBI chr 5:1,201,595...1,225,111
Ensembl chr 5:1,201,595...1,225,111 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 EXP
IAGP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile
ClinVar Annotator: match by term: Infantile dystonia-parkinsonism		 CTD
ClinVar		 PMID:9536098 PMID:10889530 PMID:16103889 PMID:16171832 PMID:16199547 More... NCBI chr 5:1,392,794...1,445,440
Ensembl chr 5:1,392,794...1,445,440 		JBrowse link
G SLC9A3 solute carrier family 9 member A3 IAGP ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile ClinVar PMID:21112253 PMID:28492532 NCBI chr 5:470,456...524,449
Ensembl chr 5:470,456...524,449 		JBrowse link
G TERT telomerase reverse transcriptase IAGP ClinVar Annotator: match by term: Infantile dystonia-parkinsonism
ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile		 ClinVar PMID:21112253 PMID:28492532 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068 		JBrowse link
G TPPP tubulin polymerization promoting protein IAGP ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile ClinVar PMID:21112253 PMID:28492532 NCBI chr 5:659,862...700,727
Ensembl chr 5:659,862...693,352 		JBrowse link
G TRIP13 thyroid hormone receptor interactor 13 IAGP ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile ClinVar PMID:21112253 PMID:28492532 NCBI chr 5:892,884...919,348
Ensembl chr 5:892,884...919,357 		JBrowse link
G ZDHHC11 zinc finger DHHC-type containing 11 IAGP ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile ClinVar PMID:21112253 PMID:28492532 NCBI chr 5:795,605...860,563
Ensembl chr 5:795,605...858,973 		JBrowse link
G ZDHHC11B zinc finger DHHC-type containing 11B IAGP ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile ClinVar PMID:21112253 PMID:28492532 NCBI chr 5:710,355...784,729
Ensembl chr 5:710,355...784,729 		JBrowse link
infantile parkinsonism-dystonia 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC18A2 solute carrier family 18 member A2 IAGP ClinVar Annotator: match by term: PARKINSONISM-DYSTONIA, INFANTILE, 2
ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile, 2
ClinVar Annotator: match by term: Abnormal dense granules		 ClinVar
OMIM		 PMID:23363473 PMID:25741868 PMID:26497564 PMID:28492532 PMID:28716265 More... NCBI chr10:117,241,114...117,279,430
Ensembl chr10:117,241,093...117,279,430 		JBrowse link
G SLC18A2-AS1 SLC18A2 antisense RNA 1 IAGP ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile, 2 ClinVar PMID:25741868 NCBI chr10:117,238,765...117,241,997
Ensembl chr10:117,238,762...117,241,998 		JBrowse link
INTELLECTUAL DEVELOPMENTAL DISORDER WITH LANGUAGE IMPAIRMENT AND EARLY-ONSET DOPA-RESPONSIVE DYSTONIA-PARKINSONISM term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR4A2 nuclear receptor subfamily 4 group A member 2 IAGP ClinVar Annotator: match by term: Intellectual developmental disorder with language impairment and early-onset DOPA-responsive dystonia-parkinsonism ClinVar
OMIM		 PMID:25741868 PMID:29758562 PMID:29770430 PMID:31428396 PMID:31922365 More... NCBI chr 2:156,324,437...156,332,721
Ensembl chr 2:156,324,437...156,342,348 		JBrowse link
Kufor-Rakeb syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP13A2 ATPase cation transporting 13A2 IAGP
ISS
EXP		 ClinVar Annotator: match by term: Parkinson disease 9
ClinVar Annotator: match by term: Kufor-Rakeb syndrome
OMIM:606693
CTD Direct Evidence: marker/mechanism		 ClinVar
MouseDO
CTD
OMIM		 PMID:495089 PMID:9536098 PMID:12169656 PMID:16199547 PMID:16964263 More... NCBI chr 1:16,985,958...17,011,928
Ensembl chr 1:16,985,958...17,011,928 		JBrowse link
G LOC129929540 ATAC-STARR-seq lymphoblastoid silent region 339 IAGP ClinVar Annotator: match by term: Kufor-Rakeb syndrome ClinVar PMID:25741868 PMID:26467025 PMID:28492532
late onset Parkinson's disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide EXP
IAGP		 CTD Direct Evidence: marker/mechanism CTD
OMIM		 NCBI chr 4:99,336,497...99,352,746
Ensembl chr 4:99,336,497...99,352,746 		JBrowse link
G ATXN2 ataxin 2 susceptibility EXP
IAGP		 CTD Direct Evidence: marker/mechanism CTD
OMIM		 NCBI chr12:111,452,214...111,599,673
Ensembl chr12:111,443,485...111,599,676 		JBrowse link
G ATXN3 ataxin 3 EXP
IAGP		 CTD Direct Evidence: marker/mechanism CTD
OMIM		 NCBI chr14:92,044,775...92,106,582
Ensembl chr14:92,044,496...92,106,621 		JBrowse link
G ATXN8OS ATXN8 opposite strand lncRNA EXP
IAGP		 CTD Direct Evidence: marker/mechanism CTD
OMIM		 NCBI chr13:70,107,421...70,171,738
Ensembl chr13:70,107,213...70,171,738 		JBrowse link
G DNAJB6 DnaJ heat shock protein family (Hsp40) member B6 IAGP ClinVar Annotator: match by term: Parkinson disease, late-onset ClinVar PMID:25741868 PMID:28492532 NCBI chr 7:157,337,004...157,417,439
Ensembl chr 7:157,335,381...157,417,439 		JBrowse link
G DNAJC13 DnaJ heat shock protein family (Hsp40) member C13 IAGP ClinVar Annotator: match by term: Parkinson disease, late-onset ClinVar PMID:24218364 PMID:25118025 PMID:27270108 NCBI chr 3:132,417,502...132,539,032
Ensembl chr 3:132,417,502...132,539,032 		JBrowse link
G DTD2 D-aminoacyl-tRNA deacylase 2 IAGP ClinVar Annotator: match by term: Parkinson disease, late-onset ClinVar PMID:20818383 PMID:22072591 PMID:25741868 PMID:32518176 PMID:33224084 NCBI chr14:31,446,036...31,457,506
Ensembl chr14:31,446,036...31,457,506 		JBrowse link
G EIF4G1 eukaryotic translation initiation factor 4 gamma 1 IAGP
EXP		 ClinVar Annotator: match by term: PARKINSON DISEASE 18, AUTOSOMAL DOMINANT, SUSCEPTIBILITY TO
ClinVar Annotator: match by term: Parkinson disease 18, autosomal dominant, susceptibility to
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:21907011 PMID:23408866 PMID:25368108 PMID:25741868 PMID:28492532 NCBI chr 3:184,314,606...184,335,358
Ensembl chr 3:184,314,495...184,335,358 		JBrowse link
G FGF20 fibroblast growth factor 20 IAGP ClinVar Annotator: match by term: Parkinson disease, late-onset ClinVar PMID:18252210 PMID:19133659 NCBI chr 8:16,992,181...17,002,345
Ensembl chr 8:16,992,181...17,002,345 		JBrowse link
G GBA1 glucosylceramidase beta 1 susceptibility IAGP
EXP		 ClinVar Annotator: match by term: Parkinson disease, late-onset
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hereditary late onset Parkinson disease		 ClinVar
OMIM
CTD		 PMID:1348297 PMID:1415223 PMID:1487244 PMID:1558964 PMID:1589760 More... NCBI chr 1:155,234,452...155,244,627
Ensembl chr 1:155,234,452...155,244,699 		JBrowse link
G GLUD2 glutamate dehydrogenase 2 IAGP
EXP		 ClinVar Annotator: match by term: Parkinson disease, late-onset
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD		 PMID:19826450 PMID:25741868 NCBI chr  X:121,047,610...121,050,094
Ensembl chr  X:121,047,610...121,050,094 		JBrowse link
G GPR33 G protein-coupled receptor 33 IAGP ClinVar Annotator: match by term: Parkinson disease, late-onset ClinVar PMID:20818383 PMID:22072591 PMID:25741868 PMID:32518176 PMID:33224084 NCBI chr14:31,482,875...31,488,039
Ensembl chr14:31,482,875...31,488,039 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 susceptibility IAGP DNA:polymorphism:exon:A>G313 (human) RGD PMID:17250723 RGD:5148021 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G HEATR5A HEAT repeat containing 5A IAGP ClinVar Annotator: match by term: Parkinson disease, late-onset ClinVar PMID:20818383 PMID:22072591 PMID:25741868 PMID:32518176 PMID:33224084 NCBI chr14:31,291,788...31,420,550
Ensembl chr14:31,291,788...31,420,550 		JBrowse link
G HEATR5A-DT HEATR5A divergent transcript IAGP ClinVar Annotator: match by term: Parkinson disease, late-onset ClinVar PMID:20818383 PMID:22072591 PMID:25741868 PMID:32518176 PMID:33224084 NCBI chr14:31,420,758...31,452,883
Ensembl chr14:31,420,286...31,452,883 		JBrowse link
G HLA-DRA major histocompatibility complex, class II, DR alpha IAGP DNA:SNP:intron: (rs3129882) (human) RGD PMID:21791235 RGD:5490156 NCBI chr 6:32,439,887...32,445,046
Ensembl chr 6:32,439,878...32,445,046 		JBrowse link
G LOC106627981 GBA recombination region IAGP ClinVar Annotator: match by term: Parkinson disease, late-onset
ClinVar Annotator: match by term: Hereditary late onset Parkinson disease		 ClinVar PMID:1348297 PMID:1487244 PMID:1558964 PMID:1704891 PMID:1864608 More... NCBI chr 1:155,233,639...155,240,092 JBrowse link
G LOC126861911 MED14-independent group 3 enhancer GRCh37_chr14:31961704-31962903 IAGP ClinVar Annotator: match by term: Parkinson disease, late-onset ClinVar PMID:20818383 PMID:22072591 PMID:25741868 PMID:32518176 PMID:33224084 NCBI chr14:31,492,498...31,493,697 JBrowse link
G LOC129390617 MPRA-validated peak2131 silencer IAGP ClinVar Annotator: match by term: Parkinson disease, late-onset ClinVar PMID:20818383 PMID:22072591 PMID:25741868 PMID:32518176 PMID:33224084 NCBI chr14:31,653,210...31,653,410 JBrowse link
G LOC129934941 ATAC-STARR-seq lymphoblastoid silent region 12016 IAGP ClinVar Annotator: match by term: Parkinson disease, late-onset ClinVar PMID:12496759 PMID:15079038 PMID:15184637 PMID:19429166 PMID:24126627
G LOC130055450 ATAC-STARR-seq lymphoblastoid silent region 5656 IAGP ClinVar Annotator: match by term: Parkinson disease, late-onset ClinVar PMID:20818383 PMID:22072591 PMID:25741868 PMID:32518176 PMID:33224084 NCBI chr14:31,420,011...31,420,130 JBrowse link
G LOC130055451 ATAC-STARR-seq lymphoblastoid active region 8232 IAGP ClinVar Annotator: match by term: Parkinson disease, late-onset ClinVar PMID:20818383 PMID:22072591 PMID:25741868 PMID:32518176 PMID:33224084 NCBI chr14:31,420,241...31,420,290 JBrowse link
G LOC130055452 ATAC-STARR-seq lymphoblastoid active region 8233 IAGP ClinVar Annotator: match by term: Parkinson disease, late-onset ClinVar PMID:20818383 PMID:22072591 PMID:25741868 PMID:32518176 PMID:33224084 NCBI chr14:31,420,721...31,420,870 JBrowse link
G LOC130055453 ATAC-STARR-seq lymphoblastoid active region 8236 IAGP ClinVar Annotator: match by term: Parkinson disease, late-onset ClinVar PMID:20818383 PMID:22072591 PMID:25741868 PMID:32518176 PMID:33224084 NCBI chr14:31,544,372...31,544,521 JBrowse link
G LRRK2 leucine rich repeat kinase 2 IAGP ClinVar Annotator: match by term: Parkinson disease, late-onset ClinVar PMID:15541309 PMID:15680455 PMID:15680456 PMID:15680457 PMID:15726496 More... NCBI chr12:40,224,997...40,369,285
Ensembl chr12:40,196,744...40,369,285 		JBrowse link
G MAPT microtubule associated protein tau IAGP
EXP		 ClinVar Annotator: match by term: Parkinson disease, late-onset
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hereditary late onset Parkinson disease		 ClinVar
OMIM
CTD		 PMID:25741868 PMID:26467025 PMID:28492532 NCBI chr17:45,894,554...46,028,334
Ensembl chr17:45,894,527...46,028,334 		JBrowse link
G MGC32805 uncharacterized LOC153163 IAGP ClinVar Annotator: match by term: Parkinson disease, late-onset ClinVar PMID:12761037 PMID:18366718 PMID:28492532 NCBI chr 5:122,436,497...122,479,087
Ensembl chr 5:122,436,497...122,479,087 		JBrowse link
G MT-ND1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 IAGP ClinVar Annotator: match by term: Parkinson disease, late-onset ClinVar PMID:8104867 PMID:15972314 NCBI chr MT:3,307...4,262
Ensembl chr MT:3,307...4,262 		JBrowse link
G MT-TT mitochondrially encoded tRNA-Thr (ACN) EXP CTD Direct Evidence: marker/mechanism CTD NCBI chr MT:15,888...15,953
Ensembl chr MT:15,888...15,953 		JBrowse link
G NR4A2 nuclear receptor subfamily 4 group A member 2 IAGP
EXP		 ClinVar Annotator: match by term: Parkinson disease, late-onset
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD		 PMID:12496759 PMID:15079038 PMID:15184637 PMID:19429166 PMID:23066323 More... NCBI chr 2:156,324,437...156,332,721
Ensembl chr 2:156,324,437...156,342,348 		JBrowse link
G NUBPL NUBP iron-sulfur cluster assembly factor, mitochondrial IAGP ClinVar Annotator: match by term: Parkinson disease, late-onset ClinVar PMID:20818383 PMID:22072591 PMID:25741868 PMID:32518176 PMID:33224084 NCBI chr14:31,561,404...31,861,224
Ensembl chr14:31,489,956...31,861,224 		JBrowse link
G NUBPL-DT NUBPL divergent transcript IAGP ClinVar Annotator: match by term: Parkinson disease, late-onset ClinVar PMID:20818383 PMID:22072591 PMID:25741868 PMID:32518176 PMID:33224084 NCBI chr14:31,553,499...31,561,331 JBrowse link
G PARK7 Parkinsonism associated deglycase IAGP ClinVar Annotator: match by term: Parkinson disease, late-onset ClinVar NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505 		JBrowse link
G PINK1 PTEN induced kinase 1 IAGP ClinVar Annotator: match by term: Parkinson disease, late-onset ClinVar NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511 		JBrowse link
G PINK1-AS PINK1 antisense RNA IAGP ClinVar Annotator: match by term: Parkinson disease, late-onset ClinVar NCBI chr 1:20,642,657...20,652,193
Ensembl chr 1:20,642,657...20,652,193 		JBrowse link
G PODXL podocalyxin like IAGP ClinVar Annotator: match by term: Parkinson disease, late-onset ClinVar PMID:26864383 PMID:28492532 NCBI chr 7:131,500,271...131,556,628
Ensembl chr 7:131,500,262...131,558,217 		JBrowse link
G PSAP prosaposin IAGP ClinVar Annotator: match by term: PARKINSON DISEASE 24, AUTOSOMAL DOMINANT, SUSCEPTIBILITY TO
ClinVar Annotator: match by term: Parkinson disease 24, autosomal dominant, susceptibility to
ClinVar Annotator: match by term: Parkinson disease, late-onset		 ClinVar
OMIM		 PMID:9536098 PMID:17576681 PMID:25741868 PMID:28492532 PMID:30632081 More... NCBI chr10:71,816,298...71,851,251
Ensembl chr10:71,816,298...71,851,251 		JBrowse link
G SNCAIP synuclein alpha interacting protein EXP
IAGP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Parkinson disease, late-onset		 CTD
ClinVar		 PMID:12761037 PMID:18366718 PMID:28492532 NCBI chr 5:122,311,353...122,464,219
Ensembl chr 5:122,311,354...122,464,219 		JBrowse link
G TBP TATA-box binding protein susceptibility EXP
IAGP		 CTD Direct Evidence: marker/mechanism CTD
OMIM		 NCBI chr 6:170,554,369...170,572,859
Ensembl chr 6:170,554,302...170,572,870 		JBrowse link
G VPS35 VPS35 retromer complex component IAGP ClinVar Annotator: match by term: Parkinson disease, late-onset ClinVar NCBI chr16:46,656,132...46,689,178
Ensembl chr16:46,656,132...46,689,518 		JBrowse link
Lewy body dementia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:16141792 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322 		JBrowse link
G AIF1 allograft inflammatory factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19276553 NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021 		JBrowse link
G ANXA5 annexin A5 IEP protein:increased expression: plasma RGD PMID:23576984 RGD:10053729 NCBI chr 4:121,667,946...121,696,980
Ensembl chr 4:121,667,946...121,696,995 		JBrowse link
G APOE apolipoprotein E IEP protein:increased expression:neuron: RGD PMID:21907175 RGD:7771591 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G BECN1 beclin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19628769 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350 		JBrowse link
G CCR1 C-C motif chemokine receptor 1 IEP RGD PMID:14595653 RGD:5688166 NCBI chr 3:46,201,711...46,208,313
Ensembl chr 3:46,201,711...46,208,313 		JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit IEP RGD PMID:15465084 RGD:1358509 NCBI chr20:63,343,223...63,361,349
Ensembl chr20:63,343,223...63,378,401 		JBrowse link
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit IEP RGD PMID:15465084 RGD:1358509 NCBI chr15:32,030,483...32,173,018
Ensembl chr15:31,923,438...32,173,018 		JBrowse link
G EDN1 endothelin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19276553 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G ELK1 ETS transcription factor ELK1 IEP RGD PMID:20126313 RGD:7488914 NCBI chr  X:47,635,520...47,650,604
Ensembl chr  X:47,635,521...47,650,604 		JBrowse link
G ENO2 enolase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30236862 NCBI chr12:6,914,580...6,923,697
Ensembl chr12:6,913,745...6,923,698 		JBrowse link
G GBA1 glucosylceramidase beta 1 susceptibility IAGP
EXP		 DNA:missense mutations:cds:multiple (human)
ClinVar Annotator: match by term: Lewy body dementia
ClinVar Annotator: match by term: Diffuse Lewy body disease
CTD Direct Evidence: marker/mechanism
DNA:missense mutations, frameshift mutation:cds:multiple (human)		 OMIM
ClinVar
CTD
RGD		 PMID:1301953 PMID:1348297 PMID:1415223 PMID:1487244 PMID:1558964 More... RGD:5508424, RGD:12791014 NCBI chr 1:155,234,452...155,244,627
Ensembl chr 1:155,234,452...155,244,699 		JBrowse link
G GFAP glial fibrillary acidic protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:19276553 NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937 		JBrowse link
G GPR37 G protein-coupled receptor 37 IEP RGD PMID:14991825 RGD:13504666 NCBI chr 7:124,743,885...124,765,792
Ensembl chr 7:124,743,885...124,765,792 		JBrowse link
G IGF1R insulin like growth factor 1 receptor IEP
EXP
IDA		 mRNA:altered expression:brain:
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:19276553 PMID:19276553 PMID:19276553 RGD:5129515, RGD:5129515 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530 		JBrowse link
G IGF2 insulin like growth factor 2 IEP
EXP		 mRNA:decreased expression:frontal cortex
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:19276553 PMID:19276553 RGD:5129515 NCBI chr11:2,129,117...2,149,566
Ensembl chr11:2,129,112...2,158,391 		JBrowse link
G IGF2R insulin like growth factor 2 receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:19276553 NCBI chr 6:159,969,082...160,111,504
Ensembl chr 6:159,969,082...160,113,507 		JBrowse link
G INS insulin EXP CTD Direct Evidence: marker/mechanism CTD PMID:19276553 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221 		JBrowse link
G INSR insulin receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:19276553 NCBI chr19:7,112,265...7,294,414
Ensembl chr19:7,112,255...7,294,414 		JBrowse link
G KLK6 kallikrein related peptidase 6 IAGP RGD PMID:12928483 RGD:1358597 NCBI chr19:50,958,631...50,969,591
Ensembl chr19:50,958,631...50,969,673 		JBrowse link
G LOC106627981 GBA recombination region IAGP ClinVar Annotator: match by term: Diffuse Lewy body disease
ClinVar Annotator: match by term: Lewy body dementia		 ClinVar PMID:1301953 PMID:1348297 PMID:1487244 PMID:1558964 PMID:1704891 More... NCBI chr 1:155,233,639...155,240,092 JBrowse link
G LOC129389225 MPRA-validated peak5070 silencer IAGP ClinVar Annotator: match by term: Lewy body dementia ClinVar PMID:14593171 PMID:14755720 PMID:15451224 PMID:15451225 PMID:16358335 More... NCBI chr 4:89,898,305...89,898,505 JBrowse link
G MAG myelin associated glycoprotein EXP CTD Direct Evidence: marker/mechanism CTD PMID:19276553 NCBI chr19:35,292,161...35,313,807
Ensembl chr19:35,292,125...35,313,807 		JBrowse link
G MAP2 microtubule associated protein 2 IEP
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:30236862 PMID:20024519 RGD:6483091 NCBI chr 2:209,424,047...209,734,112
Ensembl chr 2:209,424,047...209,734,147 		JBrowse link
G MMRN1 multimerin 1 IAGP ClinVar Annotator: match by term: Lewy body dementia ClinVar PMID:14593171 PMID:14755720 PMID:15451224 PMID:15451225 PMID:16358335 More... NCBI chr 4:89,879,511...89,954,614
Ensembl chr 4:89,879,532...89,954,629 		JBrowse link
G NEFL neurofilament light chain IEP protein:increased expression:CSF (human) RGD PMID:29368621 PMID:29391125 RGD:127284889, RGD:127285384 NCBI chr 8:24,950,955...24,956,612
Ensembl chr 8:24,950,955...24,956,721 		JBrowse link
G NGF nerve growth factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:19276553 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770 		JBrowse link
G NGFR nerve growth factor receptor IEP protein:decreased expression:brain RGD PMID:8347330 RGD:10413896 NCBI chr17:49,495,293...49,515,008
Ensembl chr17:49,495,293...49,515,008 		JBrowse link
G NOS2 nitric oxide synthase 2 IDA RGD PMID:10674474 RGD:1358529 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19276553 NCBI chr 1:156,815,750...156,881,850
Ensembl chr 1:156,815,636...156,881,850 		JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19276553 NCBI chr 9:84,668,522...85,027,054
Ensembl chr 9:84,668,375...85,095,751 		JBrowse link
G PCNA proliferating cell nuclear antigen IEP protein:increased expression:Hippocampal sub ventricular zone,Subgranular layer: RGD PMID:20665591 RGD:10448971 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:30236862 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase IEP RGD PMID:17467279 RGD:10412737 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G SEPTIN4 septin 4 IEP RGD PMID:12695511 RGD:13504670 NCBI chr17:58,520,256...58,544,328
Ensembl chr17:58,520,250...58,544,368 		JBrowse link
G SNCA synuclein alpha IAGP
IEP
EXP
IMP		 ClinVar Annotator: match by term: Lewy body dementia
protein:decreased expression:cerebral spinal fluid:
CTD Direct Evidence: marker/mechanism
protein:increased expression:hippocampus
protein:increased expression:cerebrospinal fluid		 ClinVar
CTD
OMIM
RGD		 PMID:9197268 PMID:9499430 PMID:9506559 PMID:9536098 PMID:9827625 More... RGD:6478704, RGD:13506723, RGD:6480103, RGD:6480095, RGD:6478792 NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315 		JBrowse link
G SNCA-AS1 SNCA antisense RNA 1 IAGP ClinVar Annotator: match by term: Lewy body dementia ClinVar PMID:14593171 PMID:14755720 PMID:15451224 PMID:15451225 PMID:16358335 More... NCBI chr 4:89,836,401...89,841,991
Ensembl chr 4:89,836,408...89,841,978 		JBrowse link
G SNCB synuclein beta IAGP
EXP
IEP
IMP		 DNA:mutations:cds:p.V70M, P123H (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Lewy body dementia
protein:increased expression:hippocampus		 CTD
ClinVar
OMIM
RGD		 PMID:15365127 PMID:21045828 PMID:25741868 PMID:26332674 PMID:31589614 More... RGD:6219004, RGD:6480095, RGD:6478800 NCBI chr 5:176,620,082...176,630,534
Ensembl chr 5:176,620,082...176,630,556 		JBrowse link
G SNCG synuclein gamma IAGP
IEP		 protein:increased expression:hippocampus
protein:increased expression:cerebrospinal fluid		 RGD PMID:20697047 PMID:10557341 PMID:18577885 RGD:6478704, RGD:6480095, RGD:6478792 NCBI chr10:86,955,759...86,963,258
Ensembl chr10:86,958,599...86,963,258 		JBrowse link
G SOD2 superoxide dismutase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16141792 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G TARDBP TAR DNA binding protein IEP RGD PMID:20669025 RGD:5687180 NCBI chr 1:11,012,654...11,030,528
Ensembl chr 1:11,012,344...11,030,528 		JBrowse link
G TH tyrosine hydroxylase EXP CTD Direct Evidence: marker/mechanism CTD PMID:30236862 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815 		JBrowse link
G VCP valosin containing protein IAGP ClinVar Annotator: match by term: Lewy body dementia ClinVar PMID:28492532 NCBI chr 9:35,056,064...35,072,625
Ensembl chr 9:35,053,928...35,072,668 		JBrowse link
MPTP Poisoning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP9 aquaporin 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29566083 NCBI chr15:58,138,169...58,185,911
Ensembl chr15:58,138,169...58,185,911 		JBrowse link
G IL17A interleukin 17A EXP CTD Direct Evidence: marker/mechanism CTD PMID:31351185 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G INS insulin EXP CTD Direct Evidence: therapeutic CTD PMID:26364587 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221 		JBrowse link
Parkinson's disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2M alpha-2-macroglobulin onset IEA
IAGP		 DNA:polymorphism: :p.I1000V (human) GAD
RGD		 PMID:15118671 PMID:12133586 RGD:1331525, RGD:10046014 NCBI chr12:9,067,708...9,116,229
Ensembl chr12:9,067,664...9,116,229 		JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20558393 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase IEP
ISO		 protein:increased phosphorylation:striatum:
protein:increased expression:brain:		 RGD PMID:20823226 PMID:24412932 PMID:24412932 RGD:8693409, RGD:8693592, RGD:8693592 NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,043...130,887,675 		JBrowse link
G ACE angiotensin I converting enzyme IEA GAD PMID:15118671 RGD:1331525 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ACHE acetylcholinesterase (Cartwright blood group) IEP RGD PMID:19474411 RGD:5509846 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974 		JBrowse link
G ADARB2 adenosine deaminase RNA specific B2 (inactive) EXP CTD Direct Evidence: marker/mechanism CTD PMID:25475535 NCBI chr10:1,177,313...1,737,525
Ensembl chr10:1,177,313...1,737,525 		JBrowse link
G ADCY5 adenylate cyclase 5 ISS OMIM:168600 | OMIM:300557 | OMIM:556500 | OMIM:602404 | OMIM:606852 | OMIM:607688 | OMIM:610297 | OMIM:613164 | OMIM:613643 | OMIM:614251 MouseDO NCBI chr 3:123,282,296...123,449,090
Ensembl chr 3:123,282,296...123,449,090 		JBrowse link
G ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide ISS OMIM:168600 | OMIM:300557 | OMIM:556500 | OMIM:602404 | OMIM:606852 | OMIM:607688 | OMIM:610297 | OMIM:613164 | OMIM:613643 | OMIM:614251 MouseDO NCBI chr 4:99,412,263...99,435,342
Ensembl chr 4:99,412,261...99,435,510 		JBrowse link
G AFDN afadin, adherens junction formation factor IEP protein:decreased expression: caudate-putamen, substantia nigra RGD PMID:23393160 RGD:13838733 NCBI chr 6:167,826,564...167,972,023
Ensembl chr 6:167,826,893...167,972,023 		JBrowse link
G AGTR1 angiotensin II receptor type 1 IEP protein:decreased expression:caudate nucleus,putamen,substantia nigra: RGD PMID:8666063 RGD:10047397 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008 		JBrowse link
G AIF1 allograft inflammatory factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19276553 NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 no_association IAGP
IEP		 DNA:SNPs:introns:multiple (human)
DNA:SNPs, haplotype:introns:multiple (human)
protein:altered expression:brain		 RGD PMID:21741444 PMID:18395980 PMID:19800394 RGD:5509064, RGD:5509076, RGD:5509074 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member EXP CTD Direct Evidence: marker/mechanism CTD PMID:24491970 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532 		JBrowse link
G ANG angiogenin IAGP DNA:mutations:multiple RGD PMID:22190368 RGD:6892707 NCBI chr14:20,684,177...20,694,186
Ensembl chr14:20,684,177...20,698,971 		JBrowse link
G ANXA5 annexin A5 IEP protein:decreased expression:cerebrospinal fluid: RGD PMID:10584677 RGD:10053728 NCBI chr 4:121,667,946...121,696,980
Ensembl chr 4:121,667,946...121,696,995 		JBrowse link
G APAF1 apoptotic peptidase activating factor 1 IEP RGD PMID:24835407 RGD:13503333 NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,290...98,735,433 		JBrowse link
G APOA1 apolipoprotein A1 IEP protein: altered expression: cerebrospinal fluid: 2 different isoforms RGD PMID:20085559 RGD:5508216 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G APOE apolipoprotein E IEP protein:increased expression:neuron: RGD PMID:21907175 RGD:7771591 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G ARPC3 actin related protein 2/3 complex subunit 3 treatment ISO RGD PMID:20713051 RGD:11049454 NCBI chr12:110,434,823...110,450,337
Ensembl chr12:110,434,823...110,450,422 		JBrowse link
G ATG7 autophagy related 7 ISS OMIM:168600 | OMIM:300557 | OMIM:556500 | OMIM:602404 | OMIM:606852 | OMIM:607688 | OMIM:610297 | OMIM:613164 | OMIM:613643 | OMIM:614251 MouseDO NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665 		JBrowse link
G ATM ATM serine/threonine kinase IDA protein:increased serine phosphorylation:cingulate gyrus RGD PMID:20502937 RGD:10053605 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,223,044...108,369,102 		JBrowse link
G ATP13A2 ATPase cation transporting 13A2 IAGP
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:23628791 PMID:25149416 PMID:26223426 RGD:10450518 NCBI chr 1:16,985,958...17,011,928
Ensembl chr 1:16,985,958...17,011,928 		JBrowse link
G AXIN2 axin 2 ameliorates ISO RGD PMID:31078578 RGD:151356747 NCBI chr17:65,528,563...65,561,648
Ensembl chr17:65,528,563...65,561,648 		JBrowse link
G B2M beta-2-microglobulin IEP protein:increased expression:corpus striatum RGD PMID:7605592 RGD:6482706 NCBI chr15:44,711,517...44,718,145
Ensembl chr15:44,711,358...44,718,851 		JBrowse link
G BAG5 BAG cochaperone 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28348719 NCBI chr14:103,556,551...103,562,657
Ensembl chr14:103,556,545...103,562,657 		JBrowse link
G BDNF brain derived neurotrophic factor no_association IEA
EXP
IAGP
IEP		 CTD Direct Evidence: marker/mechanism
DNA:polymorphisms: :196G>A (p.V66M), 270C>T (human)
protein:decreased expression:substantia nigra pars compacta:		 CTD
RGD		 PMID:19276553 PMID:15118671 PMID:16565926 PMID:10208589 RGD:1331525, RGD:10059346, RGD:8657025 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein IEP protein:decreased expression:serum RGD PMID:16114020 RGD:7207224 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317 		JBrowse link
G BST1 bone marrow stromal cell antigen 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19915576 NCBI chr 4:15,703,065...15,774,173
Ensembl chr 4:15,703,065...15,738,313 		JBrowse link
G CASP3 caspase 3 treatment IDA RGD PMID:16505307 RGD:13503345 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP9 caspase 9 IDA protein:increased activity:blood, leukocyte RGD PMID:16505307 RGD:13503345 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CAST calpastatin IAGP
IEP		 DNA:SNP:intron: (rs1559085) (human)
protein:decreased expression:substantia nigra, dopaminergic neuron		 RGD PMID:20127884 PMID:10722997 RGD:5509800, RGD:5683320 NCBI chr 5:95,961,429...96,774,683
Ensembl chr 5:96,525,267...96,779,595 		JBrowse link
G CCK cholecystokinin no_association IAGP RGD PMID:10668930 RGD:1626086 NCBI chr 3:42,257,826...42,266,185
Ensembl chr 3:42,257,825...42,266,185 		JBrowse link
G CCN2 cellular communication network factor 2 ISO protein:increased expression:substantia nigra (rat) RGD PMID:19463894 RGD:2314505 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372 		JBrowse link
G CEACAM6 CEA cell adhesion molecule 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25475535 NCBI chr19:41,755,530...41,772,211
Ensembl chr19:41,750,977...41,772,211 		JBrowse link
G CNTNAP2 contactin associated protein 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25475535 NCBI chr 7:146,116,801...148,420,998
Ensembl chr 7:146,116,002...148,420,998 		JBrowse link
G COL19A1 collagen type XIX alpha 1 chain EXP CTD Direct Evidence: marker/mechanism CTD PMID:25475535 NCBI chr 6:69,866,556...70,212,468
Ensembl chr 6:69,866,556...70,212,468 		JBrowse link
G COX10 cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 ISS OMIM:168600 | OMIM:300557 | OMIM:556500 | OMIM:602404 | OMIM:606852 | OMIM:607688 | OMIM:610297 | OMIM:613164 | OMIM:613643 | OMIM:614251 MouseDO NCBI chr17:14,069,504...14,208,677
Ensembl chr17:14,069,490...14,231,736 		JBrowse link
G CP ceruloplasmin EXP CTD Direct Evidence: marker/mechanism CTD PMID:19159062 PMID:25758665 NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829 		JBrowse link
G CRH corticotropin releasing hormone IEP protein:decreased expression:cerebral cortex (human) RGD PMID:3502064 RGD:5508835 NCBI chr 8:66,176,376...66,178,464
Ensembl chr 8:66,176,376...66,178,464 		JBrowse link
G CRIPTO cripto, EGF-CFC family member treatment ISO RGD PMID:20641036 RGD:11561895 NCBI chr 3:46,574,535...46,582,457
Ensembl chr 3:46,574,534...46,582,457 		JBrowse link
G CRP C-reactive protein IEP RGD PMID:22426659 RGD:6482307 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 no_association
susceptibility		 IAGP DNA:missense mutation:cds:p.I462V (human)
DNA:polymorphisms (human)		 RGD PMID:11793160 PMID:8872868 PMID:11484167 RGD:5147678, RGD:5147681, RGD:5147679 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:14991823 PMID:15174030 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16510128 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G DBH dopamine beta-hydroxylase susceptibility IEP
IAGP		 protein:increased expression:frontal cortex (human)
DNA:snp:5' utr:g.-1021C>T (human)		 RGD PMID:19276553 PMID:14991826 RGD:5129515, RGD:1358583 NCBI chr 9:133,636,363...133,659,329
Ensembl chr 9:133,636,363...133,659,329 		JBrowse link
G DBN1 drebrin 1 treatment ISO levodopainduced; protein:increased expression:striatum: RGD PMID:23241013 RGD:10398811 NCBI chr 5:177,456,610...177,473,634
Ensembl chr 5:177,456,608...177,474,401 		JBrowse link
G DDC dopa decarboxylase ISO
EXP
IMP		 protein:altered expression:arcuate nucleus ((rat)
CTD Direct Evidence: therapeutic
human gene in a rat model		 CTD
RGD		 PMID:2969953 PMID:11445284 PMID:15935614 PMID:12703659 PMID:9853519 RGD:5129231, RGD:4139893, RGD:5129121 NCBI chr 7:50,458,442...50,565,405
Ensembl chr 7:50,458,436...50,565,405 		JBrowse link
G DDIT4 DNA damage inducible transcript 4 EXP CTD Direct Evidence: therapeutic CTD PMID:17005863 NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,919...72,276,036 		JBrowse link
G DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit IAGP ClinVar Annotator: match by term: Parkinson Disease, Recessive ClinVar PMID:25741868 PMID:28492532 NCBI chr 1:20,651,777...20,661,369
Ensembl chr 1:20,651,767...20,661,544 		JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 treatment ISO RGD PMID:28863860 RGD:150519888 NCBI chr 1:162,630,863...162,787,405
Ensembl chr 1:162,631,373...162,787,405 		JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 ISO protein:altered localization, decreased expression:striatum:redistribution from synapse to vesicles (rat) RGD PMID:15703272 RGD:2306834 NCBI chr 3:197,042,560...197,299,321
Ensembl chr 3:197,042,560...197,299,330 		JBrowse link
G DLG4 discs large MAGUK scaffold protein 4 ISO protein:altered localization, decreased expression:striatum:redistribution from synapse to vesicles (rat) RGD PMID:15703272 RGD:2306834 NCBI chr17:7,187,187...7,220,050
Ensembl chr17:7,187,187...7,219,841 		JBrowse link
G DNAJB6 DnaJ heat shock protein family (Hsp40) member B6 IAGP ClinVar Annotator: match by term: Susceptibility to Parkinson's Disease ClinVar PMID:25741868 PMID:28492532 NCBI chr 7:157,337,004...157,417,439
Ensembl chr 7:157,335,381...157,417,439 		JBrowse link
G DNAJC13 DnaJ heat shock protein family (Hsp40) member C13 IAGP RGD PMID:25701813 RGD:10450845 NCBI chr 3:132,417,502...132,539,032
Ensembl chr 3:132,417,502...132,539,032 		JBrowse link
G DNAJC6 DnaJ heat shock protein family (Hsp40) member C6 IAGP RGD PMID:25639775 RGD:10450521 NCBI chr 1:65,264,749...65,415,871
Ensembl chr 1:65,248,219...65,415,871 		JBrowse link
G DNM1L dynamin 1 like EXP CTD Direct Evidence: marker/mechanism CTD PMID:28215578 NCBI chr12:32,679,301...32,745,650
Ensembl chr12:32,679,200...32,745,650 		JBrowse link
G DRAXIN dorsal inhibitory axon guidance protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:25475535 NCBI chr 1:11,686,635...11,725,857
Ensembl chr 1:11,691,710...11,725,857 		JBrowse link
G DRD1 dopamine receptor D1 treatment ISO
EXP		 protein:decreased expression:striatum (rat)
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:8558425 PMID:16365282 PMID:23041629 RGD:7248455, RGD:7248595 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182 		JBrowse link
G DRD2 dopamine receptor D2 ISO
ISS
EXP		 protein:increased expression:striatum (rat)
CTD Direct Evidence: therapeutic		 MouseDO
CTD
RGD		 PMID:8558425 PMID:18289173 RGD:2311585 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691 		JBrowse link
G DRD3 dopamine receptor D3 severity IEP protein:increased expression:blood, lymphocyte
mRNA:decreased expression:blood, lymphocyte		 RGD PMID:10495037 PMID:8618685 RGD:5686418, RGD:5686419 NCBI chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407 		JBrowse link
G DRD5 dopamine receptor D5 IEP protein:increased expression:blood, lymphocyte RGD PMID:10495037 RGD:5686418 NCBI chr 4:9,781,634...9,784,009
Ensembl chr 4:9,781,634...9,784,009 		JBrowse link
G DTD2 D-aminoacyl-tRNA deacylase 2 IAGP ClinVar Annotator: match by term: Parkinson's disease ClinVar PMID:20818383 PMID:22072591 PMID:25741868 PMID:32518176 PMID:33224084 NCBI chr14:31,446,036...31,457,506
Ensembl chr14:31,446,036...31,457,506 		JBrowse link
G EDN1 endothelin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19276553 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G EGF epidermal growth factor disease_progression IEP RGD PMID:21520231 RGD:10059679 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G EGFR epidermal growth factor receptor IEP protein:decreased expression:forebrain RGD PMID:15857400 RGD:2289955 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 IDA RGD PMID:15567511 RGD:10395348 NCBI chr 2:37,099,210...37,156,980
Ensembl chr 2:37,099,210...37,157,522 		JBrowse link
G EN1 engrailed homeobox 1 IAGP
ISS		 DNA:SNP:enhancer: (rs1438852) (human) MouseDO
RGD		 PMID:19345444 RGD:5687197 NCBI chr 2:118,842,171...118,847,648
Ensembl chr 2:118,842,171...118,847,648 		JBrowse link
G ENO2 enolase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30236862 NCBI chr12:6,914,580...6,923,697
Ensembl chr12:6,913,745...6,923,698 		JBrowse link
G EPHX1 epoxide hydrolase 1 no_association IAGP DNA:missense mutation:exon:p.Y113H (human)
DNA:missense mutations:exons:p.Y113H (499T>C), p.H139R (578A>G) (human)		 RGD PMID:10720475 PMID:11692079 RGD:5490167, RGD:5688390 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563 		JBrowse link
G EPHX2 epoxide hydrolase 2 no_association IAGP DNA:missense mutation, insertion:exons:p.R287Q (898G>A), p.S402_R403insR (1246_1247insTCG) (human) RGD PMID:11692079 RGD:5688390 NCBI chr 8:27,491,143...27,548,626
Ensembl chr 8:27,490,781...27,545,564 		JBrowse link
G EPO erythropoietin treatment IMP RGD PMID:19727138 RGD:10400901 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 IEP protein:decreased expression:forebrain RGD PMID:15857400 RGD:2289955 NCBI chr17:39,688,094...39,728,658
Ensembl chr17:39,687,914...39,730,426 		JBrowse link
G ESR2 estrogen receptor 2 onset IAGP DNA:polymorphism: :1730A>G(human) RGD PMID:15219649 RGD:5508776 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G FAS Fas cell surface death receptor IEP protein:decreased expression:neurones of the substantia nigra pars: RGD PMID:11054182 RGD:12903948 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FASLG Fas ligand ISO
IEP		 protein:increased expression:substantia nigra pars compacta, striatum (rat)
protein:decreased expression:neurones of the substantia nigra pars:		 RGD PMID:17959308 PMID:11054182 RGD:2290172, RGD:12903948 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G FBP1 fructose-bisphosphatase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18353766 NCBI chr 9:94,603,133...94,640,263
Ensembl chr 9:94,603,133...94,640,249 		JBrowse link
G FBXO7 F-box protein 7 IAGP ClinVar Annotator: match by term: Parkinson Disease, Recessive ClinVar
RGD		 PMID:26223426 RGD:10450518 NCBI chr22:32,474,811...32,498,829
Ensembl chr22:32,474,676...32,498,829 		JBrowse link
G FCER2 Fc epsilon receptor II EXP CTD Direct Evidence: marker/mechanism CTD PMID:25475535 NCBI chr19:7,688,776...7,702,131
Ensembl chr19:7,688,758...7,702,146 		JBrowse link
G FEZ1 fasciculation and elongation protein zeta 1 ISO RGD PMID:23888906 RGD:13208826 NCBI chr11:125,442,881...125,496,265
Ensembl chr11:125,442,881...125,592,568 		JBrowse link
G FGB fibrinogen beta chain EXP CTD Direct Evidence: marker/mechanism CTD PMID:23233872 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807 		JBrowse link
G GAK cyclin G associated kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:20711177 NCBI chr 4:849,277...932,316
Ensembl chr 4:849,276...932,373 		JBrowse link
G GBA1 glucosylceramidase beta 1 onset
no_association		 IAGP
EXP		 DNA:missense mutations:cds:multiple (human)
ClinVar Annotator: match by term: Susceptibility to Parkinson's Disease
CTD Direct Evidence: marker/mechanism
DNA:missense mutations:cds:p.E326K, p.T369M (human)
DNA:missense mutation:cds:p.N370S (human)
DNA:missense mutations:cds:p.K-26R, p.K186R, p.N370S (human)
DNA:mutations:multiple (human)		 ClinVar
CTD
RGD		 PMID:1348297 PMID:1897529 PMID:1899336 PMID:1971142 PMID:1972019 More... RGD:5508422, RGD:5508425, RGD:5508427, RGD:5508429, RGD:10450518, RGD:10450521, RGD:12791016 NCBI chr 1:155,234,452...155,244,627
Ensembl chr 1:155,234,452...155,244,699 		JBrowse link
G GDF5 growth differentiation factor 5 treatment IDA
ISO		 mRNA:increased expression:striatum: RGD PMID:22436046 PMID:24373993 RGD:12738227, RGD:12738228 NCBI chr20:35,433,347...35,454,749
Ensembl chr20:35,433,347...35,454,746 		JBrowse link
G GDNF glial cell derived neurotrophic factor IEP
EXP		 mRNA:increased expression:putamen
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:11031079 PMID:16324109 PMID:16644101 RGD:6218968 NCBI chr 5:37,812,677...37,840,041
Ensembl chr 5:37,812,677...37,840,041 		JBrowse link
G GFAP glial fibrillary acidic protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:19276553 NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937 		JBrowse link
G GJC2 gap junction protein gamma 2 treatment ISO RGD PMID:21561882 RGD:13208520 NCBI chr 1:228,149,930...228,159,826
Ensembl chr 1:228,149,930...228,159,826 		JBrowse link
G GPR33 G protein-coupled receptor 33 IAGP ClinVar Annotator: match by term: Parkinson's disease ClinVar PMID:20818383 PMID:22072591 PMID:25741868 PMID:32518176 PMID:33224084 NCBI chr14:31,482,875...31,488,039
Ensembl chr14:31,482,875...31,488,039 		JBrowse link
G GPR37 G protein-coupled receptor 37 IEP RGD PMID:14991825 RGD:13504666 NCBI chr 7:124,743,885...124,765,792
Ensembl chr 7:124,743,885...124,765,792 		JBrowse link
G GPX1 glutathione peroxidase 1 EXP CTD Direct Evidence: therapeutic CTD PMID:15824117 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO Protein: decreased expression: brain RGD PMID:17996024 RGD:5685370 NCBI chr11:67,266,473...67,286,556
Ensembl chr11:67,266,473...67,286,556 		JBrowse link
G GRK3 G protein-coupled receptor kinase 3 ISO protein:decreased expression:caudate putamen (rat) RGD PMID:17996024 RGD:5685370 NCBI chr22:25,564,675...25,729,294
Ensembl chr22:25,564,675...25,729,294 		JBrowse link
G GRK5 G protein-coupled receptor kinase 5 no_association IAGP
ISO
IEP		 DNA: snps: :rs871196, rs2420616, rs7069375, rs4752293
protein: decreased expression: brain		 RGD PMID:21184589 PMID:17996024 PMID:17125886 RGD:5688382, RGD:5685370, RGD:5688384 NCBI chr10:119,207,571...119,459,745
Ensembl chr10:119,207,571...119,459,745 		JBrowse link
G GRK6 G protein-coupled receptor kinase 6 IMP
ISO		 human gene in rat model
protein: decreased expression: brain		 RGD PMID:22090514 PMID:17996024 RGD:5684916, RGD:5685370 NCBI chr 5:177,425,523...177,442,891
Ensembl chr 5:177,403,204...177,442,901 		JBrowse link
G GRN granulin precursor no_association IEP
IAGP		 protein:decreased expression:serum
DNA:SNP:3' utr:*78C>T (rs5848) (human)		 RGD PMID:23398167 PMID:19473366 RGD:10401642, RGD:10401644 NCBI chr17:44,345,302...44,353,106
Ensembl chr17:44,345,246...44,353,106 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta treatment ISO RGD PMID:23094836 RGD:10045553 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G GSTA4 glutathione S-transferase alpha 4 ISO
EXP		 mRNA:increased expression:striatum (mouse)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16510128 PMID:20964710 RGD:5687772 NCBI chr 6:52,977,953...52,995,284
Ensembl chr 6:52,977,948...52,995,304 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 susceptibility
no_association
onset		 IAGP
EXP		 CTD Direct Evidence: marker/mechanism
DNA:deletion:cds (human)		 CTD
RGD		 PMID:17449559 PMID:17403576 PMID:10534244 PMID:10720475 RGD:5148019, RGD:7488959, RGD:5490167 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G GSTO1 glutathione S-transferase omega 1 susceptibility
onset		 IAGP DNA:polymorphism:exon:p. A140D (rs4925) (human) RGD PMID:17194543 PMID:14570706 RGD:5490299, RGD:1358651 NCBI chr10:104,254,173...104,267,455
Ensembl chr10:104,235,356...104,267,459 		JBrowse link
G GSTO2 glutathione S-transferase omega 2 susceptibility
onset		 IAGP DNA:polymorphism: : -183 A>G (rs2297235)(human)
DDNA:polymorphism: : -183 A>G (rs2297235)(human)		 RGD PMID:17194543 PMID:14570706 RGD:5490299, RGD:1358651 NCBI chr10:104,269,184...104,304,950
Ensembl chr10:104,268,873...104,304,950 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 IAGP
EXP		 DNA:del: :
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:17190945 PMID:23721876 PMID:9802272 RGD:1358669 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G GSTT1 glutathione S-transferase theta 1 IAGP DNA:deletion: : RGD PMID:10953187 RGD:5490165
G HBB hemoglobin subunit beta IEP protein:decreased expression:brain, mitochondrion RGD PMID:24333691 RGD:10449046 NCBI chr11:5,225,464...5,227,071
Ensembl chr11:5,225,464...5,229,395 		JBrowse link
G HBG1 hemoglobin subunit gamma 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25475535 NCBI chr11:5,248,269...5,249,857
Ensembl chr11:5,248,269...5,249,857 		JBrowse link
G HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 ISO mRNA:increased expression:neuron: RGD PMID:19320057 RGD:9693679 NCBI chr 1:155,277,463...155,289,848
Ensembl chr 1:155,277,463...155,289,848 		JBrowse link
G HEATR5A HEAT repeat containing 5A IAGP ClinVar Annotator: match by term: Parkinson's disease ClinVar PMID:20818383 PMID:22072591 PMID:25741868 PMID:32518176 PMID:33224084 NCBI chr14:31,291,788...31,420,550
Ensembl chr14:31,291,788...31,420,550 		JBrowse link
G HEATR5A-DT HEATR5A divergent transcript IAGP ClinVar Annotator: match by term: Parkinson's disease ClinVar PMID:20818383 PMID:22072591 PMID:25741868 PMID:32518176 PMID:33224084 NCBI chr14:31,420,758...31,452,883
Ensembl chr14:31,420,286...31,452,883 		JBrowse link
G HFE homeostatic iron regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:16824219 NCBI chr 6:26,087,429...26,098,343
Ensembl chr 6:26,087,281...26,098,343 		JBrowse link
G HGF hepatocyte growth factor EXP CTD Direct Evidence: therapeutic CTD PMID:16791285 NCBI chr 7:81,699,010...81,770,047
Ensembl chr 7:81,699,010...81,770,438 		JBrowse link
G HLA-DRA major histocompatibility complex, class II, DR alpha onset IAGP
EXP		 DNA:SNP:intron: (rs3129882) (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:20711177 PMID:20711177 RGD:5490158 NCBI chr 6:32,439,887...32,445,046
Ensembl chr 6:32,439,878...32,445,046 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 IAGP DNA:polymorphism: :HLA-DRB1*03 (human) RGD PMID:20462916 RGD:5147576 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G HLA-DRB5 major histocompatibility complex, class II, DR beta 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27713094 NCBI chr 6:32,517,353...32,530,287
Ensembl chr 6:32,517,353...32,530,287 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase IMP RGD PMID:18184918 RGD:5508459 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G HMOX1 heme oxygenase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21318773 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HNMT histamine N-methyltransferase no_association IAGP RGD PMID:19773194 PMID:17985251 RGD:5509775, RGD:5509778 NCBI chr 2:137,964,473...138,016,364
Ensembl chr 2:137,964,020...138,016,364 		JBrowse link
G HSF1 heat shock transcription factor 1 treatment ISO protein:decreased expression:midbrain (rat) RGD PMID:24852355 PMID:24296154 RGD:10402545, RGD:10402753 NCBI chr 8:144,291,604...144,314,720
Ensembl chr 8:144,291,591...144,314,720 		JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A EXP CTD Direct Evidence: therapeutic CTD PMID:15585408 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946 		JBrowse link
G HSPA4 heat shock protein family A (Hsp70) member 4 ISO protein:decreased expression:striatum (rat) RGD PMID:22186119 RGD:5686884 NCBI chr 5:133,052,013...133,106,449
Ensembl chr 5:133,052,013...133,106,449 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 IEP
ISO
IMP		 protein: decreased expression
protein: increased expression: brain		 RGD PMID:20697033 PMID:17241115 PMID:18704197 RGD:6218982, RGD:6480228, RGD:6480203 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230 		JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 disease_progression IAGP
EXP
IEP
IDA		 DNA:mutation:cds:A>T476(human)
CTD Direct Evidence: marker/mechanism
protein:decreased expression:brain
DNA:mutations:multiple:		 CTD
RGD		 PMID:16565515 PMID:20817635 PMID:16565515 PMID:18219256 PMID:19657588 RGD:6784528, RGD:6784531, RGD:6784530, RGD:6784529 NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,675 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 ISO RGD PMID:23943523 RGD:10402846 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO RGD PMID:20508280 RGD:5683633 NCBI chr 5:63,957,874...63,962,445
Ensembl chr 5:63,957,874...63,962,507 		JBrowse link
G HTRA2 HtrA serine peptidase 2 no_association ISO
IAGP		 DNA:missense mutation, transversion:cds, intron:p.G26E, g.IVS5+29T>A (human)
DNA:missense mutation:cds:p.P143A (human)
DNA:missense mutations:cds:p.A141S, p.G399S (human)
DNA:missense mutation:cds:p.R404W (human)
DNA:missense mutation:cds:p.S276C (mouse)		 RGD PMID:15509788 PMID:21338583 PMID:21701785 PMID:18364387 PMID:18401856 More... RGD:5688367, RGD:5688714, RGD:5688395, RGD:5688394, RGD:5688393, RGD:5688392, RGD:5688381 NCBI chr 2:74,529,405...74,533,556
Ensembl chr 2:74,529,596...74,533,350 		JBrowse link
G HTT huntingtin IMP RGD PMID:26192120 RGD:13452383 NCBI chr 4:3,074,681...3,243,960
Ensembl chr 4:3,041,363...3,243,957 		JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO
EXP
IEP		 protein: altered activity
CTD Direct Evidence: marker/mechanism
mRNA:altered expression:brain:		 CTD
RGD		 PMID:19276553 PMID:19703168 PMID:19276553 RGD:5686429, RGD:5129515 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530 		JBrowse link
G IGF2 insulin like growth factor 2 IEP
EXP		 mRNA:decreased expression:frontal cortex
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:19276553 PMID:19276553 RGD:5129515 NCBI chr11:2,129,117...2,149,566
Ensembl chr11:2,129,112...2,158,391 		JBrowse link
G IGF2R insulin like growth factor 2 receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:19276553 NCBI chr 6:159,969,082...160,111,504
Ensembl chr 6:159,969,082...160,113,507 		JBrowse link
G IL1B interleukin 1 beta IAGP
ISO		 RGD PMID:12070246 PMID:23159314 RGD:1358742, RGD:7175549 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21318773 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INS insulin EXP CTD Direct Evidence: marker/mechanism CTD PMID:19276553 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221 		JBrowse link
G INSR insulin receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:19276553 NCBI chr19:7,112,265...7,294,414
Ensembl chr19:7,112,255...7,294,414 		JBrowse link
G KCNJ4 potassium inwardly rectifying channel subfamily J member 4 EXP CTD Direct Evidence: therapeutic CTD PMID:18619942 NCBI chr22:38,426,327...38,455,199
Ensembl chr22:38,426,327...38,455,199 		JBrowse link
G KCNN2 potassium calcium-activated channel subfamily N member 2 ISS OMIM:168600 | OMIM:300557 | OMIM:556500 | OMIM:602404 | OMIM:606852 | OMIM:607688 | OMIM:610297 | OMIM:613164 | OMIM:613643 | OMIM:614251 MouseDO NCBI chr 5:114,055,978...114,496,496
Ensembl chr 5:114,055,926...114,496,500 		JBrowse link
G KLK6 kallikrein related peptidase 6 IAGP RGD PMID:12928483 RGD:1358597 NCBI chr19:50,958,631...50,969,591
Ensembl chr19:50,958,631...50,969,673 		JBrowse link
G L1CAM L1 cell adhesion molecule ISO RGD PMID:19995872 RGD:6483033 NCBI chr  X:153,861,514...153,886,173
Ensembl chr  X:153,861,514...153,886,173 		JBrowse link
G LEP leptin treatment ISO rat protein in a mouse model RGD PMID:17895242 RGD:10053631 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G LOC106627981 GBA recombination region IAGP ClinVar Annotator: match by term: Susceptibility to Parkinson's Disease ClinVar PMID:1348297 PMID:1897529 PMID:1899336 PMID:1971142 PMID:1972019 More... NCBI chr 1:155,233,639...155,240,092 JBrowse link
G LOC126861911 MED14-independent group 3 enhancer GRCh37_chr14:31961704-31962903 IAGP ClinVar Annotator: match by term: Parkinson's disease ClinVar PMID:20818383 PMID:22072591 PMID:25741868 PMID:32518176 PMID:33224084 NCBI chr14:31,492,498...31,493,697 JBrowse link
G LOC129390617 MPRA-validated peak2131 silencer IAGP ClinVar Annotator: match by term: Parkinson's disease ClinVar PMID:20818383 PMID:22072591 PMID:25741868 PMID:32518176 PMID:33224084 NCBI chr14:31,653,210...31,653,410 JBrowse link
G LOC130055450 ATAC-STARR-seq lymphoblastoid silent region 5656 IAGP ClinVar Annotator: match by term: Parkinson's disease ClinVar PMID:20818383 PMID:22072591 PMID:25741868 PMID:32518176 PMID:33224084 NCBI chr14:31,420,011...31,420,130 JBrowse link
G LOC130055451 ATAC-STARR-seq lymphoblastoid active region 8232 IAGP ClinVar Annotator: match by term: Parkinson's disease ClinVar PMID:20818383 PMID:22072591 PMID:25741868 PMID:32518176 PMID:33224084 NCBI chr14:31,420,241...31,420,290 JBrowse link
G LOC130055452 ATAC-STARR-seq lymphoblastoid active region 8233 IAGP ClinVar Annotator: match by term: Parkinson's disease ClinVar PMID:20818383 PMID:22072591 PMID:25741868 PMID:32518176 PMID:33224084 NCBI chr14:31,420,721...31,420,870 JBrowse link
G LOC130055453 ATAC-STARR-seq lymphoblastoid active region 8236 IAGP ClinVar Annotator: match by term: Parkinson's disease ClinVar PMID:20818383 PMID:22072591 PMID:25741868 PMID:32518176 PMID:33224084 NCBI chr14:31,544,372...31,544,521 JBrowse link
G LRRK2 leucine rich repeat kinase 2 susceptibility
no_association		 IAGP
EXP
IEP		 DNA:missense mutations:cds:multiple
ClinVar Annotator: match by term: Parkinson Disease, Dominant
ClinVar Annotator: match by term: Parkinson disease
CTD Direct Evidence: marker/mechanism
DNA:missense mutation:cds:p.N1437H (c.4309C>A) (human)
DNA:mutation: :p.R1441G (human)
DNA:missense mutation:cds:p.R1398H (human)
DNA:missense mutations:cds:p.R1628P, p.S1647T, p.G2385R (human)
DNA:missense mutation:cds:p.G2019S (human)		 ClinVar
CTD
RGD		 PMID:16172858 PMID:16633828 PMID:17019612 PMID:17388990 PMID:17659642 More... RGD:5508399, RGD:10450521, RGD:10450518, RGD:5508420, RGD:5508416, RGD:5508415, RGD:5508409, RGD:5508408, RGD:5508406, RGD:5508404 NCBI chr12:40,224,997...40,369,285
Ensembl chr12:40,196,744...40,369,285 		JBrowse link
G MAG myelin associated glycoprotein EXP CTD Direct Evidence: marker/mechanism CTD PMID:19276553 NCBI chr19:35,292,161...35,313,807
Ensembl chr19:35,292,125...35,313,807 		JBrowse link
G MAOA monoamine oxidase A EXP CTD Direct Evidence: marker/mechanism CTD PMID:17449559 NCBI chr  X:43,655,006...43,746,817
Ensembl chr  X:43,654,907...43,746,817 		JBrowse link
G MAOB monoamine oxidase B ISO
EXP
IAGP		 protein:increased activity:striatum (rat)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:21318773 PMID:17417741 PMID:9129714 RGD:2316771, RGD:1358484 NCBI chr  X:43,766,610...43,882,450
Ensembl chr  X:43,766,610...43,882,450 		JBrowse link
G MAP2 microtubule associated protein 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30236862 NCBI chr 2:209,424,047...209,734,112
Ensembl chr 2:209,424,047...209,734,147 		JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21815648 NCBI chr 6:136,557,046...136,793,091
Ensembl chr 6:136,557,046...136,793,097 		JBrowse link
G MAPT microtubule associated protein tau susceptibility IAGP
EXP		 DNA:SNP, haplotype:promoter, intron:c.-17-19950G>A (rs242557) (human)
ClinVar Annotator: match by term: Susceptibility to Parkinson's Disease
CTD Direct Evidence: marker/mechanism
DNA:SNP:intron: (rs8070723) (human)
DNA:SNPs:intron:g.38276T>A, g.87443G>A (rs242556, rs10514889) (human)
DNA:SNPs, haplotypes: :multiple		 ClinVar
CTD
RGD		 PMID:19915575 PMID:20711177 PMID:25741868 PMID:26467025 PMID:28492532 More... RGD:8158095, RGD:8158107, RGD:8158106, RGD:8158096 NCBI chr17:45,894,554...46,028,334
Ensembl chr17:45,894,527...46,028,334 		JBrowse link
G MAPT-AS1 MAPT antisense RNA 1 susceptibility IAGP DNA:SNP:intron: (rs17690703) (human) RGD PMID:22221882 RGD:8158107 NCBI chr17:45,843,356...45,895,513
Ensembl chr17:45,799,390...45,895,680 		JBrowse link
G MGC32805 uncharacterized LOC153163 IAGP ClinVar Annotator: match by term: Parkinson Disease, Dominant/Recessive ClinVar PMID:12761037 PMID:18366718 PMID:21344240 PMID:24033266 PMID:28492532 NCBI chr 5:122,436,497...122,479,087
Ensembl chr 5:122,436,497...122,479,087 		JBrowse link
G MINAR2 membrane integral NOTCH2 associated receptor 2 ISS MouseDO NCBI chr 5:129,748,094...129,766,732
Ensembl chr 5:129,748,094...129,766,732 		JBrowse link
G MIR1-2 microRNA 1-2 IEP RGD PMID:21295623 RGD:10755488 NCBI chr18:21,829,004...21,829,088
Ensembl chr18:21,829,004...21,829,088 		JBrowse link
G MIR106A microRNA 106a IEP RGD PMID:25553963 RGD:10450788 NCBI chr  X:134,170,198...134,170,278
Ensembl chr  X:134,170,198...134,170,278 		JBrowse link
G MIR132 microRNA 132 IEP RGD PMID:25553963 RGD:10450788 NCBI chr17:2,049,908...2,050,008
Ensembl chr17:2,049,908...2,050,008 		JBrowse link
G MIR155 microRNA 155 ISO RNA:increased expression: plasma extracellular vesicle RGD PMID:32326590 RGD:41404531 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044 		JBrowse link
G MIR181C microRNA 181c EXP CTD Direct Evidence: marker/mechanism CTD PMID:28770951 NCBI chr19:13,874,699...13,874,808
Ensembl chr19:13,874,699...13,874,808 		JBrowse link
G MIR19B1 microRNA 19b-1 IEP RGD PMID:22003392 RGD:10755479 NCBI chr13:91,351,192...91,351,278
Ensembl chr13:91,351,192...91,351,278 		JBrowse link
G MIR21 microRNA 21 ISO RNA:increased expression: plasma extracellular vesicle RGD PMID:32326590 RGD:41404531 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G MIR210 microRNA 210 ISO RNA:increased expression: plasma extracellular vesicle RGD PMID:32326590 RGD:41404531 NCBI chr11:568,089...568,198
Ensembl chr11:568,089...568,198 		JBrowse link
G MIR22 microRNA 22 IEP RGD PMID:21295623 RGD:10755488 NCBI chr17:1,713,903...1,713,987
Ensembl chr17:1,713,903...1,713,987 		JBrowse link
G MIR29B1 microRNA 29b-1 IEP RGD PMID:22003392 RGD:10755479 NCBI chr 7:130,877,459...130,877,539
Ensembl chr 7:130,877,459...130,877,539 		JBrowse link
G MIR301A microRNA 301a IEP RGD PMID:22003392 RGD:10755479 NCBI chr17:59,151,136...59,151,221
Ensembl chr17:59,151,136...59,151,221 		JBrowse link
G MIR34B microRNA 34b IEP RGD PMID:21558425 RGD:10755477 NCBI chr11:111,512,938...111,513,021
Ensembl chr11:111,512,938...111,513,021 		JBrowse link
G MIR34C microRNA 34c IEP RGD PMID:21558425 RGD:10755477 NCBI chr11:111,513,439...111,513,515
Ensembl chr11:111,513,439...111,513,515 		JBrowse link
G MT-ATP6 mitochondrially encoded ATP synthase membrane subunit 6 susceptibility IAGP DNA:SNP:cds:m.9055A>G (human) RGD PMID:12618962 RGD:5490292 NCBI chr MT:8,527...9,207
Ensembl chr MT:8,527...9,207 		JBrowse link
G MT-ND1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 no_association IAGP
IEP		 DNA:missense mutation:cds:m.4216T>C (human)
mRNA:decreased expression:substantia nigra, neuron		 RGD PMID:11022854 PMID:11506395 PMID:16784756 RGD:5148018, RGD:8657117, RGD:5508706 NCBI chr MT:3,307...4,262
Ensembl chr MT:3,307...4,262 		JBrowse link
G MT-ND2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 IAGP DNA:point mutation: :m.5460G>A (human)
DNA:missense mutation::m.5460G>A		 RGD PMID:8723226 PMID:10737123 RGD:2302313, RGD:5507832 NCBI chr MT:4,470...5,511
Ensembl chr MT:4,470...5,511 		JBrowse link
G MT-ND3 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 IAGP
ISO		 DNA:polymorphism:exon:m.10398A>G(human)
ClinVar Annotator: match by term: Parkinson disease, resistance to
protein: decreased activity: brain: MPTP model of Parkinson disease
protein: decreased activity: striatum: rotenone model of Parkinson disease 		ClinVar
RGD		 PMID:6343397 PMID:17066297 PMID:15975594 PMID:21291942 PMID:21484267 RGD:5491206, RGD:5687692, RGD:5687691 NCBI chr MT:10,059...10,404
Ensembl chr MT:10,059...10,404 		JBrowse link
G MT-ND4 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 IAGP DNA:missense mutations: :11253T>C, 12084C>T (human) RGD PMID:10737123 RGD:5507832 NCBI chr MT:10,760...12,137
Ensembl chr MT:10,760...12,137 		JBrowse link
G MTA1 metastasis associated 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27044752 NCBI chr14:105,419,827...105,470,729
Ensembl chr14:105,419,820...105,470,729 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase EXP CTD Direct Evidence: marker/mechanism CTD PMID:30726997 NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455 		JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase susceptibility IAGP DNA:polymorphism: :1049A>G (human) RGD PMID:21070756 RGD:5508183 NCBI chr 5:7,850,859...7,901,113
Ensembl chr 5:7,851,186...7,906,025 		JBrowse link
G NANOG Nanog homeobox treatment ISO mouse gene in a rat model;mRNA, protein:increased expression:embryonic stem cell RGD PMID:24954161 RGD:9681444 NCBI chr12:7,789,402...7,799,146
Ensembl chr12:7,787,794...7,799,146 		JBrowse link
G NAT2 N-acetyltransferase 2 susceptibility IAGP DNA:polymorphism RGD PMID:9343502 RGD:2303766 NCBI chr 8:18,386,301...18,401,218
Ensembl chr 8:18,391,282...18,401,218 		JBrowse link
G NCAPG2 non-SMC condensin II complex subunit G2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25475535 NCBI chr 7:158,631,169...158,704,804
Ensembl chr 7:158,631,169...158,704,804 		JBrowse link
G NDUFA13 NADH:ubiquinone oxidoreductase subunit A13 IEP RGD PMID:26605748 RGD:13504667 NCBI chr19:19,516,225...19,528,198
Ensembl chr19:19,515,736...19,529,054 		JBrowse link
G NDUFB8 NADH:ubiquinone oxidoreductase subunit B8 IEP RGD PMID:26605748 RGD:13504667 NCBI chr10:100,523,729...100,529,923
Ensembl chr10:100,523,740...100,530,000 		JBrowse link
G NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1 onset ISO protein:increased oxidation:brain, mitochondrion (mouse) RGD PMID:21196577 RGD:6484690 NCBI chr 2:206,114,817...206,159,444
Ensembl chr 2:206,114,817...206,159,509 		JBrowse link
G NDUFS4 NADH:ubiquinone oxidoreductase subunit S4 ISO RGD PMID:21383081 RGD:6484691 NCBI chr 5:53,560,639...53,683,338
Ensembl chr 5:53,560,633...53,683,338 		JBrowse link
G NDUFV2 NADH:ubiquinone oxidoreductase core subunit V2 susceptibility IAGP DNA:polymorphism: :p.A29V RGD PMID:9570948 RGD:2302386 NCBI chr18:9,102,699...9,134,341
Ensembl chr18:9,102,630...9,134,345 		JBrowse link
G NECTIN2 nectin cell adhesion molecule 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25475535 NCBI chr19:44,846,297...44,889,223
Ensembl chr19:44,846,175...44,889,223 		JBrowse link
G NEDD8 NEDD8 ubiquitin like modifier IEP RGD PMID:12533840 RGD:1549458 NCBI chr14:24,216,857...24,232,367
Ensembl chr14:24,216,857...24,232,367 		JBrowse link
G NEFL neurofilament light chain IEP protein:increased expression:CSF (human) RGD PMID:29391125 RGD:127285384 NCBI chr 8:24,950,955...24,956,612
Ensembl chr 8:24,950,955...24,956,721 		JBrowse link
G NGF nerve growth factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:19276553 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770 		JBrowse link
G NGFR nerve growth factor receptor IEP protein:decreased expression:brain RGD PMID:8347330 RGD:10413896 NCBI chr17:49,495,293...49,515,008
Ensembl chr17:49,495,293...49,515,008 		JBrowse link
G NOS1 nitric oxide synthase 1 IEP
EXP
IAGP		 RNA, protein:increased expression:neutrophil
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:26383258 PMID:11020342 PMID:11809160 RGD:5132632, RGD:1358519 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO protein:increased expression:striatum (mouse) RGD PMID:21970803 RGD:5509573 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOX1 NADPH oxidase 1 ameliorates ISO RGD PMID:23077033 RGD:329961565 NCBI chr  X:100,843,324...100,874,359
Ensembl chr  X:100,843,324...100,874,359 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17188257 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NQO2 N-ribosyldihydronicotinamide:quinone dehydrogenase 2 susceptibility IAGP DNA:deletion:promoter: (human) RGD PMID:18314446 RGD:11073691 NCBI chr 6:2,999,894...3,019,755
Ensembl chr 6:2,987,987...3,019,755 		JBrowse link
G NR4A1 nuclear receptor subfamily 4 group A member 1 treatment ISO compared to wild-type and untreated RGD PMID:29530712 RGD:40924655 NCBI chr12:52,022,832...52,059,503
Ensembl chr12:52,022,832...52,059,507 		JBrowse link
G NR4A2 nuclear receptor subfamily 4 group A member 2 IAGP
ISS		 DNA:insertion:intron:g.7048_7049insG (human)
OMIM:168600 | OMIM:300557 | OMIM:556500 | OMIM:602404 | OMIM:606852 | OMIM:607688 | OMIM:610297 | OMIM:613164 | OMIM:613643 | OMIM:614251
ClinVar Annotator: match by term: Parkinson Disease, Dominant/Recessive		 MouseDO
ClinVar
RGD		 PMID:11914402 RGD:1358553 NCBI chr 2:156,324,437...156,332,721
Ensembl chr 2:156,324,437...156,342,348 		JBrowse link
G NTSR1 neurotensin receptor 1 IEP RGD PMID:7700529 RGD:9743906 NCBI chr20:62,708,836...62,762,771
Ensembl chr20:62,708,836...62,762,771 		JBrowse link
G NUBPL NUBP iron-sulfur cluster assembly factor, mitochondrial IAGP ClinVar Annotator: match by term: Parkinson's disease ClinVar PMID:20818383 PMID:22072591 PMID:25741868 PMID:32518176 PMID:33224084 NCBI chr14:31,561,404...31,861,224
Ensembl chr14:31,489,956...31,861,224 		JBrowse link
G NUBPL-DT NUBPL divergent transcript IAGP ClinVar Annotator: match by term: Parkinson's disease ClinVar PMID:20818383 PMID:22072591 PMID:25741868 PMID:32518176 PMID:33224084 NCBI chr14:31,553,499...31,561,331 JBrowse link
G OGG1 8-oxoguanine DNA glycosylase IEP protein:increased expression:substantia nigra, neuron RGD PMID:15841414 RGD:8657142 NCBI chr 3:9,749,952...9,783,108
Ensembl chr 3:9,749,944...9,788,219 		JBrowse link
G OPTN optineurin ISO protein:increased expression:substantia nigra (rat) RGD PMID:27473339 RGD:13432580 NCBI chr10:13,100,082...13,138,308
Ensembl chr10:13,099,449...13,138,308 		JBrowse link
G ORC6 origin recognition complex subunit 6 IAGP ClinVar Annotator: match by term: Parkinson Disease, Dominant ClinVar PMID:25741868 NCBI chr16:46,689,659...46,698,394
Ensembl chr16:46,689,643...46,698,394 		JBrowse link
G PARK7 Parkinsonism associated deglycase onset IAGP
EXP
ISO		 DNA:missense mutation, deletion: :L166P
ClinVar Annotator: match by term: Parkinson Disease, Recessive
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
RGD		 PMID:12953260 PMID:15784737 PMID:17010972 PMID:20423725 PMID:20800516 More... RGD:1601073, RGD:12880446, RGD:10450523 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 susceptibility
no_association		 IAGP DNA:polymorphisms:promoter, exon:g.-410C>T, g.845_846dupAC (human)
DNA:snps:multiple (human)		 RGD PMID:17362997 PMID:21767974 RGD:5510024, RGD:5510021 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PENK proenkephalin ISO mRNA:increased expression:striatum: RGD PMID:11501038 RGD:10003114 NCBI chr 8:56,440,957...56,446,641
Ensembl chr 8:56,436,674...56,446,671 		JBrowse link
G PHACTR2 phosphatase and actin regulator 2 IAGP DNA: snp: intron: rs11155313 RGD PMID:19429005 RGD:6483095 NCBI chr 6:143,536,878...143,831,185
Ensembl chr 6:143,536,845...143,831,185 		JBrowse link
G PINK1 PTEN induced kinase 1 IAGP
ISO
EXP		 ClinVar Annotator: match by term: Parkinson Disease, Recessive
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
RGD		 PMID:17010972 PMID:21366594 PMID:22043175 PMID:24374061 PMID:25149416 More... RGD:10450518, RGD:11560775, RGD:12880446, RGD:10450521 NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511 		JBrowse link
G PINK1-AS PINK1 antisense RNA IAGP ClinVar Annotator: match by term: Parkinson Disease, Recessive ClinVar PMID:25741868 PMID:28492532 NCBI chr 1:20,642,657...20,652,193
Ensembl chr 1:20,642,657...20,652,193 		JBrowse link
G PITX3 paired like homeodomain 3 ISO
ISS		 OMIM:168600 | OMIM:300557 | OMIM:556500 | OMIM:602404 | OMIM:606852 | OMIM:607688 | OMIM:610297 | OMIM:613164 | OMIM:613643 | OMIM:614251 MouseDO
RGD		 PMID:18573342 RGD:11535079 NCBI chr10:102,230,189...102,241,512
Ensembl chr10:102,230,189...102,241,512 		JBrowse link
G PLA2G6 phospholipase A2 group VI onset
no_association		 IAGP DNA:missense muations, nonsense mutation: :p.F72L, p.Q452X, p.R635Q (human)
DNA:missense mutation:cds:p.P806R (c.2417C>G) (human)		 RGD PMID:20938027 PMID:21368765 RGD:6482733, RGD:6482734 NCBI chr22:38,111,495...38,181,830
Ensembl chr22:38,111,495...38,214,778 		JBrowse link
G POLG DNA polymerase gamma, catalytic subunit onset IAGP associated with Ophthalmoplegia, Chronic Progressive External;DNA:mutations: :
associated with Ophthalmoplegia, Chronic Progressive External;DNA:mutation:cds:p.K512M(human)
DNA:missense mutations:exons:p.R853W,p.G737R(human)		 RGD PMID:15351195 PMID:23865558 PMID:16634032 RGD:8694175, RGD:8694203, RGD:8694201 NCBI chr15:89,316,320...89,334,824
Ensembl chr15:89,305,198...89,334,861 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha onset IAGP
ISS
EXP
IEP		 DNA:SNPs:intron, 3' utr: (rs2970848, rs6821591) (human)
CTD Direct Evidence: marker/mechanism		 MouseDO
CTD
RGD		 PMID:30236862 PMID:21595954 PMID:21376232 RGD:6484270, RGD:6484271 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G PPP1R9B protein phosphatase 1 regulatory subunit 9B ISO protein:altered localization:striate nucleus (rat) RGD PMID:18372251 RGD:10043801 NCBI chr17:50,133,737...50,150,677
Ensembl chr17:50,133,737...50,150,677 		JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha IEP protein:decreased tyrosine phosphorylation:brain (human) RGD PMID:24395787 RGD:8693390 NCBI chr 5:134,194,332...134,226,073
Ensembl chr 5:134,194,035...134,226,073 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase treatment IAGP
EXP
ISO
IEP
IMP		 DNA:deletions:exons: (human)
CTD Direct Evidence: marker/mechanism
protein:increased tyrosine-phosphorylation:substantia nigra, striatum,
DNA:mutations:multiple (human)		 CTD
RGD		 PMID:12588799 PMID:15198987 PMID:15882845 PMID:16573651 PMID:17010972 More... RGD:9693725, RGD:13432567, RGD:13432563, RGD:13432207, RGD:10450521, RGD:10450518, RGD:8693409, RGD:10413859, RGD:737763 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G PTN pleiotrophin treatment ISO RGD PMID:19615368 RGD:10044022 NCBI chr 7:137,227,341...137,343,733
Ensembl chr 7:137,227,341...137,343,774 		JBrowse link
G RPL14 ribosomal protein L14 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18353766 NCBI chr 3:40,457,339...40,468,587
Ensembl chr 3:40,457,292...40,468,587 		JBrowse link
G RPL23A ribosomal protein L23a EXP CTD Direct Evidence: marker/mechanism CTD PMID:18353766 NCBI chr17:28,719,985...28,724,359
Ensembl chr17:28,719,985...28,724,359 		JBrowse link
G RPL6 ribosomal protein L6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18353766 NCBI chr12:112,405,181...112,418,835
Ensembl chr12:112,405,189...112,418,838 		JBrowse link
G RPS8 ribosomal protein S8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18353766 NCBI chr 1:44,775,540...44,778,779
Ensembl chr 1:44,775,251...44,778,779 		JBrowse link
G RRN3 RRN3 homolog, RNA polymerase I transcription factor ISS OMIM:168600 | OMIM:300557 | OMIM:556500 | OMIM:602404 | OMIM:606852 | OMIM:607688 | OMIM:610297 | OMIM:613164 | OMIM:613643 | OMIM:614251 MouseDO NCBI chr16:15,060,022...15,094,335
Ensembl chr16:15,060,033...15,094,311 		JBrowse link
G S100B S100 calcium binding protein B ISO
IMP		 RGD PMID:21725169 PMID:21402140 RGD:5508763, RGD:5508766 NCBI chr21:46,598,604...46,605,082
Ensembl chr21:46,598,604...46,605,208 		JBrowse link
G SDHA succinate dehydrogenase complex flavoprotein subunit A IEP protein:decreased expression:substantia nigra, neuron RGD PMID:26605748 RGD:13504667 NCBI chr 5:218,320...268,746
Ensembl chr 5:218,303...257,082 		JBrowse link
G SEPTIN14 septin 14 susceptibility IAGP DNA:SNPs:promoter:rs10241628, rs11981883, rs77231105 (human) RGD PMID:27115672 RGD:13504669 NCBI chr 7:55,793,540...55,862,752
Ensembl chr 7:55,793,540...55,862,755 		JBrowse link
G SEPTIN4 septin 4 IEP RGD PMID:12695511 RGD:13504670 NCBI chr17:58,520,256...58,544,328
Ensembl chr17:58,520,250...58,544,368 		JBrowse link
G SERPINF1 serpin family F member 1 severity IEP protein:increased expression:serum, extracellular exosome (human) RGD PMID:31593110 RGD:27226691 NCBI chr17:1,762,060...1,777,565
Ensembl chr17:1,762,029...1,777,565 		JBrowse link
G SLC11A2 solute carrier family 11 member 2 IAGP
IEP		 DNA:polymorphism:cds:1254T>C(human) RGD PMID:21777657 PMID:19011085 RGD:5688403, RGD:5688713 NCBI chr12:50,952,263...51,028,886
Ensembl chr12:50,979,401...51,028,566 		JBrowse link
G SLC18A2 solute carrier family 18 member A2 resistance IAGP
EXP
IEP
ISO		 DNA:snps:5' utr:g.-103C>A, g.-74C>T, g.-62G>A (human)
CTD Direct Evidence: marker/mechanism
protein:decreased expression:putamen, caudate nucleus, striatum (human)
mRNA:decreased expression:substantia nigra (rat)		 CTD
RGD		 PMID:16112329 PMID:34774656 PMID:16339215 PMID:16421508 PMID:21291984 More... RGD:5131165, RGD:5131167, RGD:5131086, RGD:5129143, RGD:5131163 NCBI chr10:117,241,114...117,279,430
Ensembl chr10:117,241,093...117,279,430 		JBrowse link
G SLC2A14 solute carrier family 2 member 14 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25475535 NCBI chr12:7,812,514...7,891,196
Ensembl chr12:7,812,512...7,891,148 		JBrowse link
G SLC30A10 solute carrier family 30 member 10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25149416 NCBI chr 1:219,910,445...219,959,098
Ensembl chr 1:219,685,427...219,959,018 		JBrowse link
G SLC38A2 solute carrier family 38 member 2 EXP CTD Direct Evidence: therapeutic CTD PMID:35728354 NCBI chr12:46,358,188...46,372,773
Ensembl chr12:46,358,188...46,372,773 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:9763484 PMID:16112329 PMID:16963468 PMID:19590691 NCBI chr 5:1,392,794...1,445,440
Ensembl chr 5:1,392,794...1,445,440 		JBrowse link
G SNCA synuclein alpha IMP
IAGP
EXP
IEP
IDA		 human gene in a mouse model
ClinVar Annotator: match by term: Parkinson Disease, Dominant
CTD Direct Evidence: marker/mechanism
protein:decreased expression:cerebral spinal fluid:
DNA:missense mutation:cds:p.S129A(human)
DNA:mutation:cds:G209A(human)
DNA:mutation:cds:p.A30P(human)
protein:increased expression:astrocyte, oligodendroglial cell		 ClinVar
CTD
RGD		 PMID:11535288 PMID:12151787 PMID:12732244 PMID:12885775 PMID:14535945 More... RGD:1302527, RGD:13506723, RGD:13506646, RGD:6480197, RGD:6480196, RGD:6480094, RGD:6478794 NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315 		JBrowse link
G SNCA-AS1 SNCA antisense RNA 1 IAGP ClinVar Annotator: match by term: Parkinson Disease, Dominant ClinVar NCBI chr 4:89,836,401...89,841,991
Ensembl chr 4:89,836,408...89,841,978 		JBrowse link
G SNCAIP synuclein alpha interacting protein IAGP ClinVar Annotator: match by term: Parkinson Disease, Dominant/Recessive
ClinVar Annotator: match by term: Parkinson's disease		 ClinVar PMID:12761037 PMID:18366718 PMID:21344240 PMID:24033266 PMID:28492532 NCBI chr 5:122,311,353...122,464,219
Ensembl chr 5:122,311,354...122,464,219 		JBrowse link
G SNCB synuclein beta onset IAGP
IEP		 DNA:SNP: :rs1352303(human)
protein:increased expression:hippocampus		 RGD PMID:17556099 PMID:10557341 RGD:6478793, RGD:6480095 NCBI chr 5:176,620,082...176,630,534
Ensembl chr 5:176,620,082...176,630,556 		JBrowse link
G SNCG synuclein gamma IEP protein:increased expression:hippocampus RGD PMID:10557341 RGD:6480095 NCBI chr10:86,955,759...86,963,258
Ensembl chr10:86,958,599...86,963,258 		JBrowse link
G SOD1 superoxide dismutase 1 treatment IMP
EXP		 human gene in a rat model
CTD Direct Evidence: marker/mechanism|therapeutic		 CTD
RGD		 PMID:15824117 PMID:16353238 PMID:21318773 PMID:16353238 RGD:8655933 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SOD2 superoxide dismutase 2 susceptibility ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17188257 PMID:18353766 PMID:25279756 PMID:11161607 RGD:13464352 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SPR sepiapterin reductase ISS OMIM:168600 | OMIM:300557 | OMIM:556500 | OMIM:602404 | OMIM:606852 | OMIM:607688 | OMIM:610297 | OMIM:613164 | OMIM:613643 | OMIM:614251 MouseDO NCBI chr 2:72,887,408...72,892,158
Ensembl chr 2:72,887,382...72,892,158 		JBrowse link
G SRRM2 serine/arginine repetitive matrix 2 IEP mRNA:splice variants:substantia nigra, amygdala, peripheral blood mononuclear cell (human) RGD PMID:20161708 RGD:11038728 NCBI chr16:2,752,638...2,771,412
Ensembl chr16:2,752,626...2,772,538 		JBrowse link
G SYNJ1 synaptojanin 1 IAGP RGD PMID:25639775 RGD:10450521 NCBI chr21:32,628,759...32,728,394
Ensembl chr21:32,628,759...32,728,040 		JBrowse link
G TALDO1 transaldolase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23233872 NCBI chr11:747,464...765,012
Ensembl chr11:747,415...765,012 		JBrowse link
G TARDBP TAR DNA binding protein IAGP
IEP		 DNA:mutation:cds:p.A382T (human) RGD PMID:21667065 PMID:20551689 RGD:5687172, RGD:5687183 NCBI chr 1:11,012,654...11,030,528
Ensembl chr 1:11,012,344...11,030,528 		JBrowse link
G TCL1B TCL1 family AKT coactivator B EXP CTD Direct Evidence: marker/mechanism CTD PMID:25475535 NCBI chr14:95,686,426...95,692,628
Ensembl chr14:95,686,426...95,692,628 		JBrowse link
G TCN2 transcobalamin 2 IMP RGD PMID:20027219 RGD:11060125 NCBI chr22:30,607,174...30,627,271
Ensembl chr22:30,607,003...30,627,271 		JBrowse link
G TFAM transcription factor A, mitochondrial susceptibility
no_association		 IAGP
ISS		 DNA:SNP:intron:IVS4+113A>G (rs2306604) (human)
OMIM:168600 | OMIM:300557 | OMIM:556500 | OMIM:602404 | OMIM:606852 | OMIM:607688 | OMIM:610297 | OMIM:613164 | OMIM:613643 | OMIM:614251
DNA:missense mutation, SNP:exon, intron:p.S12T, IVS4+113A>G (rs1937, rs2306604) (human)
DNA:missense mutation:exon:p.S12T (rs1937) (human)		 MouseDO
RGD		 PMID:19925850 PMID:17537576 PMID:18248889 RGD:14389730, RGD:6771185, RGD:6771184 NCBI chr10:58,385,410...58,399,220
Ensembl chr10:58,385,345...58,399,220 		JBrowse link
G TH tyrosine hydroxylase ISO
EXP
IEP
IMP		 CTD Direct Evidence: marker/mechanism
protein:decreased expression:striatum (human)
human gene in a rat model
protein:decreased expression:midbrain, neuron (rat)
protein:decreased expression:substantia nigra (mouse)		 CTD
RGD		 PMID:30236862 PMID:2573072 PMID:15857400 PMID:9853519 PMID:21376343 More... RGD:5129120, RGD:2289955, RGD:5129121, RGD:5128607, RGD:5128616 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815 		JBrowse link
G TMEM230 transmembrane protein 230 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27270108 NCBI chr20:5,059,116...5,113,076
Ensembl chr20:5,068,232...5,113,103 		JBrowse link
G TNF tumor necrosis factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:21318773 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B ISO mRNA:decreased expression:midbrain, dopaminergic neuron (mouse) RGD PMID:19780901 RGD:5130931 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228 		JBrowse link
G TNK2 tyrosine kinase non receptor 2 IAGP ClinVar Annotator: match by term: Parkinson disease ClinVar PMID:23686771 PMID:25741868 PMID:26595808 PMID:28492532 NCBI chr 3:195,863,364...195,908,551
Ensembl chr 3:195,863,364...195,911,945 		JBrowse link
G TNR tenascin R IAGP ClinVar Annotator: match by term: Parkinson disease ClinVar PMID:26122175 PMID:26595808 PMID:28492532 PMID:33278868 NCBI chr 1:175,315,194...175,743,595
Ensembl chr 1:175,315,194...175,743,595 		JBrowse link
G TRPM2 transient receptor potential cation channel subfamily M member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27957685 NCBI chr21:44,353,621...44,442,644
Ensembl chr21:44,350,163...44,443,081 		JBrowse link
G UCHL1 ubiquitin C-terminal hydrolase L1 IAGP ClinVar Annotator: match by term: Parkinson Disease, Dominant ClinVar PMID:25741868 PMID:28492532 NCBI chr 4:41,256,928...41,268,455
Ensembl chr 4:41,256,413...41,268,455 		JBrowse link
G VDAC1 voltage dependent anion channel 1 IEP RGD PMID:24825319 RGD:13504672 NCBI chr 5:133,971,871...134,114,540
Ensembl chr 5:133,971,871...134,004,975 		JBrowse link
G VDR vitamin D receptor onset IAGP DNA:polymorphisms: :rs4334089, rs2853559(human) RGD PMID:21309754 RGD:13217419 NCBI chr12:47,841,537...47,904,994
Ensembl chr12:47,841,537...47,943,048 		JBrowse link
G VIP vasoactive intestinal peptide IEP RGD PMID:19476518 RGD:5685606 NCBI chr 6:152,750,797...152,759,760
Ensembl chr 6:152,750,797...152,759,765 		JBrowse link
G VPS13C vacuolar protein sorting 13 homolog C IAGP ClinVar Annotator: match by term: Parkinson disease ClinVar PMID:26942284 NCBI chr15:61,852,389...62,060,447
Ensembl chr15:61,852,389...62,060,473 		JBrowse link
G VPS35 VPS35 retromer complex component IAGP
ISS
EXP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Parkinson Disease, Dominant		 MouseDO
CTD
ClinVar
RGD		 PMID:25149416 PMID:25741868 PMID:26223426 PMID:25701813 PMID:25639775 RGD:10450518, RGD:10450845, RGD:10450521 NCBI chr16:46,656,132...46,689,178
Ensembl chr16:46,656,132...46,689,518 		JBrowse link
Parkinson's disease 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC129389225 MPRA-validated peak5070 silencer IAGP ClinVar Annotator: match by term: Autosomal dominant Parkinson disease 1 ClinVar PMID:14593171 PMID:14755720 PMID:15451224 PMID:15451225 PMID:16358335 More... NCBI chr 4:89,898,305...89,898,505 JBrowse link
G MMRN1 multimerin 1 IAGP ClinVar Annotator: match by term: Autosomal dominant Parkinson disease 1 ClinVar PMID:14593171 PMID:14755720 PMID:15451224 PMID:15451225 PMID:16358335 More... NCBI chr 4:89,879,511...89,954,614
Ensembl chr 4:89,879,532...89,954,629 		JBrowse link
G SNCA synuclein alpha IAGP
ISS
EXP		 ClinVar Annotator: match by term: Autosomal dominant Parkinson disease 1
OMIM:168601
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
MouseDO
CTD		 PMID:9197268 PMID:9462735 PMID:9499430 PMID:9506559 PMID:9827625 More... NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315 		JBrowse link
G SNCA-AS1 SNCA antisense RNA 1 IAGP ClinVar Annotator: match by term: Autosomal dominant Parkinson disease 1 ClinVar PMID:14593171 PMID:14755720 PMID:15451224 PMID:15451225 PMID:16358335 More... NCBI chr 4:89,836,401...89,841,991
Ensembl chr 4:89,836,408...89,841,978 		JBrowse link
Parkinson's Disease 11 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GIGYF2 GRB10 interacting GYF protein 2 IAGP
EXP		 ClinVar Annotator: match by term: Parkinson disease 11
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:18358451 PMID:18923002 PMID:19250854 PMID:19279319 PMID:19449032 More... NCBI chr 2:232,697,331...232,860,605
Ensembl chr 2:232,697,299...232,860,605 		JBrowse link
Parkinson's Disease 13 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AUP1 AUP1 lipid droplet regulating VLDL assembly factor IAGP ClinVar Annotator: match by term: Parkinson disease 13 ClinVar PMID:18401856 PMID:18790661 NCBI chr 2:74,526,652...74,529,706
Ensembl chr 2:74,526,645...74,529,760 		JBrowse link
G HTRA2 HtrA serine peptidase 2 IAGP
EXP		 ClinVar Annotator: match by term: Parkinson disease 13, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Parkinson disease 13, autosomal dominant, susceptibility to		 ClinVar
CTD
OMIM		 PMID:15961413 PMID:18364387 PMID:18401856 PMID:18790661 PMID:19118185 More... NCBI chr 2:74,529,405...74,533,556
Ensembl chr 2:74,529,596...74,533,350 		JBrowse link
G LOC129934140 ATAC-STARR-seq lymphoblastoid active region 16072 IAGP ClinVar Annotator: match by term: Parkinson disease 13, autosomal dominant, susceptibility to ClinVar
G LOC129934143 ATAC-STARR-seq lymphoblastoid active region 16075 IAGP ClinVar Annotator: match by term: Parkinson disease 13, autosomal dominant, susceptibility to ClinVar PMID:28492532
G LOXL3 lysyl oxidase like 3 IAGP ClinVar Annotator: match by term: Parkinson disease 13 ClinVar PMID:15961413 PMID:18364387 PMID:18790661 PMID:19118185 PMID:21163861 More... NCBI chr 2:74,532,258...74,555,702
Ensembl chr 2:74,532,258...74,555,690 		JBrowse link
Parkinson's disease 14 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLA2G6 phospholipase A2 group VI IAGP
ISS
EXP		 ClinVar Annotator: match by term: DYSTONIA-PARKINSONISM, ADULT-ONSET
ClinVar Annotator: match by term: Autosomal recessive Parkinson disease 14
OMIM:612953
CTD Direct Evidence: marker/mechanism		 ClinVar
MouseDO
CTD
OMIM		 PMID:2668131 PMID:16783378 PMID:18414213 PMID:18443314 PMID:18570303 More... NCBI chr22:38,111,495...38,181,830
Ensembl chr22:38,111,495...38,214,778 		JBrowse link
G SLC39A14 solute carrier family 39 member 14 EXP CTD Direct Evidence: marker/mechanism CTD PMID:36152728 NCBI chr 8:22,367,278...22,434,129
Ensembl chr 8:22,367,278...22,434,129 		JBrowse link
Parkinson's disease 15 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBXO7 F-box protein 7 IAGP
EXP		 ClinVar Annotator: match by term: PARKINSON DISEASE 15, AUTOSOMAL RECESSIVE EARLY-ONSET
ClinVar Annotator: match by term: Parkinsonian-pyramidal syndrome
ClinVar Annotator: match by term: Parkinson disease 15
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:9536098 PMID:17576681 PMID:18513678 PMID:19038853 PMID:20603184 More... NCBI chr22:32,474,811...32,498,829
Ensembl chr22:32,474,676...32,498,829 		JBrowse link
Parkinson's disease 17 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYLK3 myosin light chain kinase 3 IAGP ClinVar Annotator: match by term: Parkinson disease 17 ClinVar PMID:28492532 NCBI chr16:46,702,282...46,763,246
Ensembl chr16:46,702,282...46,790,407 		JBrowse link
G ORC6 origin recognition complex subunit 6 IAGP ClinVar Annotator: match by term: Parkinson disease 17 ClinVar PMID:28492532 NCBI chr16:46,689,659...46,698,394
Ensembl chr16:46,689,643...46,698,394 		JBrowse link
G VPS35 VPS35 retromer complex component IAGP
ISS
EXP		 ClinVar Annotator: match by term: Parkinson disease 17
OMIM:614203
CTD Direct Evidence: marker/mechanism		 ClinVar
MouseDO
CTD
OMIM		 PMID:9536098 PMID:17576681 PMID:18342564 PMID:21763482 PMID:21763483 More... NCBI chr16:46,656,132...46,689,178
Ensembl chr16:46,656,132...46,689,518 		JBrowse link
Parkinson's disease 19A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNAJC6 DnaJ heat shock protein family (Hsp40) member C6 IAGP
EXP		 ClinVar Annotator: match by term: Parkinson disease 19a, juvenile-onset
ClinVar Annotator: match by term: Juvenile onset Parkinson disease 19A
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Parkinson disease 19B, early-onset
ClinVar Annotator: match by term: Parkinson disease 19b, early-onset		 ClinVar
CTD
OMIM		 PMID:2256350 PMID:9536098 PMID:16199547 PMID:17576681 PMID:22563501 More... NCBI chr 1:65,264,749...65,415,871
Ensembl chr 1:65,248,219...65,415,871 		JBrowse link
Parkinson's disease 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC105378098 uncharacterized LOC105378098 IAGP ClinVar Annotator: match by term: Parkinson disease 2 ClinVar PMID:28492532 NCBI chr 6:161,470,977...161,484,045 JBrowse link
G LOC121132714 Sharpr-MPRA regulatory region 4750 IAGP ClinVar Annotator: match by term: Parkinson disease 2 ClinVar PMID:28492532 NCBI chr 6:161,356,797...161,357,091 JBrowse link
G LOC123881358 Sharpr-MPRA regulatory region 5576 IAGP ClinVar Annotator: match by term: Autosomal recessive juvenile Parkinson disease 2 ClinVar PMID:28492532 NCBI chr 6:161,618,837...161,619,131 JBrowse link
G LOC126859868 MED14-independent group 3 enhancer GRCh37_chr6:162074817-162076016 IAGP ClinVar Annotator: match by term: Autosomal recessive juvenile Parkinson disease 2 ClinVar PMID:28492532 NCBI chr 6:161,653,785...161,654,984 JBrowse link
G LOC126859869 MED14-independent group 3 enhancer GRCh37_chr6:162484237-162485436 IAGP ClinVar Annotator: match by term: Autosomal recessive juvenile Parkinson disease 2 ClinVar PMID:9560156 NCBI chr 6:162,063,205...162,064,404 JBrowse link
G LOC126859870 P300/CBP strongly-dependent group 1 enhancer GRCh37_chr6:162520224-162521423 IAGP ClinVar Annotator: match by term: Autosomal recessive juvenile Parkinson disease 2 ClinVar PMID:9560156 NCBI chr 6:162,099,192...162,100,391 JBrowse link
G LOC126859871 MED14-independent group 3 enhancer GRCh37_chr6:162621359-162622558 IAGP ClinVar Annotator: match by term: Autosomal recessive juvenile Parkinson disease 2 ClinVar PMID:7565830 PMID:9560156 PMID:9851438 PMID:10072423 PMID:10319889