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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:hepatobiliary system cancer
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Accession:DOID:0080355 term browser browse the term
Definition:A gastrointestinal system cancer that is located_in the hepatobiliary system. (DO)
Synonyms:xref: EFO:0008550


show annotations for term's descendants           Sort by:
adenosquamous gallbladder carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDR2 discoidin domain receptor tyrosine kinase 2 disease_progression IDA RGD PMID:29043607 RGD:150429712 NCBI chr 1:162,630,863...162,787,405
Ensembl chr 1:162,631,373...162,787,405 		JBrowse link
G IFITM1 interferon induced transmembrane protein 1 disease_progression IDA RGD PMID:29043607 RGD:150429712 NCBI chr11:314,040...315,272
Ensembl chr11:310,041...315,272 		JBrowse link
aflatoxins-related hepatocellular carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPHX1 epoxide hydrolase 1 ISO associated with estrogen excess;protein:increased activity;liver (rat) RGD PMID:6133380 RGD:152998935 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO associated with estrogen excess;protein:increased activity;liver (rat) RGD PMID:6133380 RGD:152998935 NCBI chr22:24,583,750...24,628,996
Ensembl chr22:24,594,811...24,629,005 		JBrowse link
bile duct adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC7A5 solute carrier family 7 member 5 disease_progression IEP RGD PMID:24131658 RGD:151361287 NCBI chr16:87,830,023...87,869,507
Ensembl chr16:87,830,016...87,869,507 		JBrowse link
bile duct cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOB apolipoprotein B susceptibility IAGP DNA:polymorphisms:intron, exon:IVS6+360C>T, 56C>T (human) RGD PMID:18296645 RGD:2317550 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073 		JBrowse link
G APOE apolipoprotein E susceptibility IAGP DNA:SNP:intron:rs440446 (human) RGD PMID:18296645 RGD:2317550 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G ATM ATM serine/threonine kinase IAGP ClinVar Annotator: match by term: Bile duct cancer ClinVar PMID:9887333 PMID:17124347 PMID:20077034 PMID:25741868 PMID:26635394 More... NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102 		JBrowse link
G MIR31 microRNA 31 exacerbates IEP RNA:increased expression:bile duct (human) RGD PMID:29860474 RGD:152998990 NCBI chr 9:21,512,115...21,512,185
Ensembl chr 9:21,512,115...21,512,185 		JBrowse link
G MLH1 mutL homolog 1 IAGP ClinVar Annotator: match by term: Bile duct cancer ClinVar PMID:15340264 PMID:17510385 PMID:18307539 PMID:19419416 PMID:22136435 More... NCBI chr 3:36,993,466...37,050,846
Ensembl chr 3:36,993,226...37,050,896 		JBrowse link
G MSH2 mutS homolog 2 IAGP ClinVar Annotator: match by term: Bile duct cancer ClinVar PMID:25741868 PMID:33357406 NCBI chr 2:47,403,067...47,709,830
Ensembl chr 2:47,403,067...47,663,146 		JBrowse link
G PALB2 partner and localizer of BRCA2 IAGP ClinVar Annotator: match by term: Bile duct cancer ClinVar PMID:25741868 PMID:26467025 PMID:28492532 PMID:30287823 NCBI chr16:23,603,165...23,641,310
Ensembl chr16:23,603,160...23,641,321 		JBrowse link
G PKD1 polycystin 1, transient receptor potential channel interacting IAGP ClinVar Annotator: match by term: Bile duct cancer ClinVar PMID:12007219 PMID:16430766 PMID:17574468 PMID:25741868 PMID:26467025 More... NCBI chr16:2,088,708...2,135,898
Ensembl chr16:2,088,708...2,135,898 		JBrowse link
G POLD1 DNA polymerase delta 1, catalytic subunit IAGP ClinVar Annotator: match by term: Bile duct cancer ClinVar PMID:25741868 PMID:26467025 PMID:28492532 NCBI chr19:50,384,323...50,418,018
Ensembl chr19:50,384,204...50,418,018 		JBrowse link
G STK11 serine/threonine kinase 11 IAGP ClinVar Annotator: match by term: Bile duct cancer ClinVar PMID:25741868 PMID:28492532 NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431 		JBrowse link
G TJP1 tight junction protein 1 IEP protein:decreased expression:bile duct RGD PMID:19184677 RGD:2325030 NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915 		JBrowse link
bile duct carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MSLN mesothelin IEP protein:increased expression:bile duct RGD PMID:17276942 RGD:2326059 NCBI chr16:760,734...768,865
Ensembl chr16:760,734...768,865 		JBrowse link
G SLC7A5 solute carrier family 7 member 5 disease_progression IEP RGD PMID:24890221 RGD:151361210 NCBI chr16:87,830,023...87,869,507
Ensembl chr16:87,830,016...87,869,507 		JBrowse link
biliary tract cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOB apolipoprotein B IEP protein:increased expression:serum RGD PMID:18076041 RGD:2325763 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 IAGP DNA:polymorphism:exon:rs2606345 (human) RGD PMID:19168589 RGD:2317210 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G PPARD peroxisome proliferator activated receptor delta IEP RGD PMID:18497548 RGD:2324871 NCBI chr 6:35,342,558...35,428,178
Ensembl chr 6:35,342,558...35,428,191 		JBrowse link
childhood hepatocellular carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MET MET proto-oncogene, receptor tyrosine kinase IAGP ClinVar Annotator: match by term: Pediatric hepatocellular carcinoma ClinVar PMID:9927037 NCBI chr 7:116,672,196...116,798,377
Ensembl chr 7:116,672,196...116,798,377 		JBrowse link
cholangiocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC2 ATP binding cassette subfamily C member 2 susceptibility IAGP DNA:polymorphism:exon:c.3972C>T (human) RGD PMID:19451719 RGD:2317508 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ADRB2 adrenoceptor beta 2 IEP protein:decreased expression:liver RGD PMID:16292515 RGD:2325640 NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623 		JBrowse link
G ALB albumin disease_progression IEP
IDA 		RGD PMID:20431764 PMID:10776430 PMID:17545000 RGD:2325679, RGD:2325682, RGD:2325680 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase IEP protein:increased expression:bile duct RGD PMID:18507031 RGD:2317521 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119 		JBrowse link
G ANXA2 annexin A2 disease_progression IEP RGD PMID:20493868 RGD:2325728 NCBI chr15:60,347,151...60,397,986
Ensembl chr15:60,347,134...60,402,883 		JBrowse link
G ANXA8 annexin A8 IEP RGD PMID:19376120 RGD:2325733 NCBI chr10:47,467,993...47,991,796
Ensembl chr10:47,460,162...47,484,158 		JBrowse link
G APC APC regulator of WNT signaling pathway IDA
IAGP 		DNA:hypermethylation:promoter
DNA:loss of heterozygosity 		RGD PMID:15467712 PMID:10212000 RGD:2317198, RGD:2317205 NCBI chr 5:112,707,498...112,846,239
Ensembl chr 5:112,707,518...112,846,239 		JBrowse link
G APOA1 apolipoprotein A1 IEP protein:decreased expression:serum RGD PMID:19486127 RGD:2325756 NCBI chr11:116,835,751...116,837,622
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G ARID1A AT-rich interaction domain 1A EXP CTD Direct Evidence: marker/mechanism CTD PMID:24185509 NCBI chr 1:26,696,015...26,782,104
Ensembl chr 1:26,693,236...26,782,104 		JBrowse link
G ASPH aspartate beta-hydroxylase IDA RGD PMID:21898484 RGD:6902945 NCBI chr 8:61,500,556...61,714,592
Ensembl chr 8:61,500,556...61,714,640 		JBrowse link
G ATG101 autophagy related 101 disease_progression IEP RGD PMID:35592424 RGD:153350091 NCBI chr12:52,065,300...52,077,495
Ensembl chr12:52,069,246...52,077,495 		JBrowse link
G BAP1 BRCA1 associated deubiquitinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24185509 PMID:25231345 NCBI chr 3:52,401,008...52,410,008
Ensembl chr 3:52,401,008...52,410,008 		JBrowse link
G BIRC6 baculoviral IAP repeat containing 6 ameliorates HEP mRNA:increased expression:bile duct (human) RGD PMID:31964418 RGD:153344516 NCBI chr 2:32,357,023...32,618,878
Ensembl chr 2:32,357,023...32,619,571 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase IAGP DNA:missense mutation:cds:p.V600E (human) RGD PMID:12692057 RGD:11073239 NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A onset IEP protein:decreased expression:liver RGD PMID:15619210 RGD:2317417 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301 		JBrowse link
G CST1 cystatin SN disease_progression IEP mRNA:altered expression:liver (human) RGD PMID:31687280 RGD:152998978 NCBI chr20:23,747,562...23,750,935
Ensembl chr20:23,747,562...23,751,268 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 IAGP ClinVar Annotator: match by term: Cholangiocarcinoma ClinVar PMID:18550579 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CXCR1 C-X-C motif chemokine receptor 1 IAGP ClinVar Annotator: match by term: Cholangiocarcinoma ClinVar PMID:18550579 NCBI chr 2:218,162,841...218,166,962
Ensembl chr 2:218,162,841...218,166,962 		JBrowse link
G CYCS cytochrome c, somatic IDA RGD PMID:19788692 RGD:2317615 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260 		JBrowse link
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 HEP protein:increased expression:intrahepatic bile, extrahepatic bile duct (human) RGD PMID:23375797 RGD:151361187 NCBI chr20:54,143,538...54,173,986
Ensembl chr20:54,153,446...54,173,986 		JBrowse link
G EGF epidermal growth factor IAGP ClinVar Annotator: match by term: Cholangiocarcinoma ClinVar PMID:18550579 PMID:25741868 PMID:28492532 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G EGFR epidermal growth factor receptor EXP
IAGP 		CTD Direct Evidence: therapeutic
ClinVar Annotator: match by term: Cholangiocarcinoma 		CTD
ClinVar		 PMID:17341899 PMID:18550579 PMID:24728327 PMID:25741868 PMID:28492532 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EPO erythropoietin ISO mRNA, protein:increased expression:liver RGD PMID:23052842 RGD:10400912 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700 		JBrowse link
G EPOR erythropoietin receptor ISO mRNA, protein:increased expression:liver RGD PMID:23052842 RGD:10400912 NCBI chr19:11,377,207...11,384,314
Ensembl chr19:11,377,207...11,384,342 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16818635 NCBI chr17:39,688,094...39,728,658
Ensembl chr17:39,687,914...39,730,426 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit disease_progression
no_association 		IAGP DNA:SNP: :g.148505302C>T (rs887569) (human)
DNA:SNPs: :g.148525904C>G, (rs2302427), g.148519011C>T (rs6464926), g.148517456T>G (rs17171119) (human) 		RGD PMID:24179546 PMID:24179546 RGD:126779604, RGD:126779604 NCBI chr 7:148,807,383...148,884,291
Ensembl chr 7:148,807,257...148,884,321 		JBrowse link
G FAM66C family with sequence similarity 66 member C EXP CTD Direct Evidence: marker/mechanism CTD PMID:34418280 NCBI chr12:8,180,209...8,201,000
Ensembl chr12:8,180,204...8,226,278 		JBrowse link
G FASLG Fas ligand IDA RGD PMID:11029528 RGD:2317746 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G FGF2 fibroblast growth factor 2 IEP protein:increased expression:bile RGD PMID:11478488 RGD:2317765 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26258846 NCBI chr10:121,478,330...121,598,458
Ensembl chr10:121,478,332...121,598,458 		JBrowse link
G FSCN1 fascin actin-bundling protein 1 disease_progression IEP protein:increased expression:bile ducts RGD PMID:19721413 RGD:2317780 NCBI chr 7:5,592,816...5,606,655
Ensembl chr 7:5,592,816...5,606,655 		JBrowse link
G GNAS GNAS complex locus disease_progression IAGP
EXP 		DNA:polymorphism:393T>C (human)
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:22561520 PMID:17356712 RGD:1601377 NCBI chr20:58,839,748...58,911,192
Ensembl chr20:58,839,718...58,911,192 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 IAGP RGD PMID:24049014 RGD:14700980 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 treatment IDA
IMP 		DNA:hypermethylation:promoter
human cell line in a mouse model 		RGD PMID:15467712 PMID:12805482 RGD:2317198, RGD:14401711 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G HDAC6 histone deacetylase 6 IEP protein:increased expression:liver: RGD PMID:23370327 RGD:9681560 NCBI chr  X:48,801,398...48,824,982
Ensembl chr  X:48,801,377...48,824,982 		JBrowse link
G HGF hepatocyte growth factor ISO
IEP 		mRNA, protein:increased expression: :
protein:increased expression:serum 		RGD PMID:10827151 PMID:16974053 RGD:2317925, RGD:2317909 NCBI chr 7:81,699,010...81,770,047
Ensembl chr 7:81,699,010...81,770,438 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha IAGP ClinVar Annotator: match by term: Cholangiocarcinoma ClinVar PMID:12919954 PMID:18550579 PMID:22647679 PMID:24120591 PMID:25741868 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HIF1A-AS3 HIF1A antisense RNA 3 IAGP ClinVar Annotator: match by term: Cholangiocarcinoma ClinVar PMID:12919954 PMID:18550579 PMID:22647679 PMID:24120591 PMID:25741868 NCBI chr14:61,715,558...61,751,097
Ensembl chr14:61,678,402...61,751,163 		JBrowse link
G HNF1B HNF1 homeobox B EXP CTD Direct Evidence: marker/mechanism CTD PMID:39887605 NCBI chr17:37,686,431...37,745,059
Ensembl chr17:37,686,431...37,745,059 		JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24185509 NCBI chr 2:208,236,227...208,255,071
Ensembl chr 2:208,236,229...208,266,074 		JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24185509 NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,477 		JBrowse link
G IL10 interleukin 10 IAGP ClinVar Annotator: match by term: Cholangiocarcinoma ClinVar PMID:11121048 PMID:14657422 PMID:14657427 PMID:18550579 PMID:25741868 More... NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL19 interleukin 19 IAGP ClinVar Annotator: match by term: Cholangiocarcinoma ClinVar PMID:11121048 PMID:14657422 PMID:14657427 PMID:18550579 PMID:25741868 More... NCBI chr 1:206,770,773...206,842,981
Ensembl chr 1:206,770,764...206,842,981 		JBrowse link
G IL1B interleukin 1 beta IAGP ClinVar Annotator: match by term: Cholangiocarcinoma ClinVar PMID:18550579 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1R2 interleukin 1 receptor type 2 disease_progression IEP mRNA:altered expression:liver (human) RGD PMID:31687280 RGD:152998978 NCBI chr 2:101,991,960...102,028,544
Ensembl chr 2:101,991,960...102,028,544 		JBrowse link
G IL4R interleukin 4 receptor IEP mRNA:increased expression:bile duct RGD PMID:18798553 RGD:2317263 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778 		JBrowse link
G IL6 interleukin 6 IEP
IAGP
EXP 		ClinVar Annotator: match by term: Cholangiocarcinoma
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism 		ClinVar
CTD
RGD		 PMID:9769329 PMID:10720087 PMID:11001912 PMID:11889177 PMID:12519862 More... RGD:2317167, RGD:14975292 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IL6-AS1 IL6 antisense RNA 1 IAGP ClinVar Annotator: match by term: Cholangiocarcinoma ClinVar PMID:9769329 PMID:10720087 PMID:11001912 PMID:11889177 PMID:12519862 More... NCBI chr 7:22,725,395...22,727,620
Ensembl chr 7:22,725,395...22,727,620 		JBrowse link
G INS insulin disease_progression IEP mRNA:altered expression:liver (human) RGD PMID:31687280 RGD:152998978 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221 		JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34418280 NCBI chr 7:120,272,908...120,750,337
Ensembl chr 7:120,273,175...120,750,337 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase disease_progression IEP mRNA:altered expression:liver (human) RGD PMID:31687280 RGD:152998978 NCBI chr 4:54,657,957...54,740,715
Ensembl chr 4:54,657,267...54,740,783 		JBrowse link
G KMT2C lysine methyltransferase 2C EXP CTD Direct Evidence: marker/mechanism CTD PMID:22561520 NCBI chr 7:152,134,925...152,436,003
Ensembl chr 7:152,134,922...152,436,644 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase EXP CTD Direct Evidence: marker/mechanism CTD PMID:8968066 PMID:22561520 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936 		JBrowse link
G KRT7 keratin 7 IEP RGD PMID:18393293 RGD:2317308 NCBI chr12:52,233,243...52,255,853
Ensembl chr12:52,232,520...52,252,186 		JBrowse link
G LOC126859963 BRD4-independent group 4 enhancer GRCh37_chr7:22766269-22767468 IAGP ClinVar Annotator: match by term: Cholangiocarcinoma ClinVar PMID:9769329 PMID:10720087 PMID:11001912 PMID:11889177 PMID:12519862 More... NCBI chr 7:22,726,650...22,727,849 JBrowse link
G MDM2 MDM2 proto-oncogene disease_progression IEP protein:increased expression:intrahepatic bile duct (human) RGD PMID:15619210 RGD:2317417 NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase disease_progression IEP
ISO 		protein:increased phosphorylation:liver, carcinoma (human)
protein:increased expression:liver, biliary epithelium (rat) 		RGD PMID:16818635 PMID:14656942 RGD:2317578, RGD:2317601 NCBI chr 7:116,672,196...116,798,377
Ensembl chr 7:116,672,196...116,798,377 		JBrowse link
G MFSD4A major facilitator superfamily domain containing 4A disease_progression IEP mRNA:altered expression:liver (human) RGD PMID:31687280 RGD:152998978 NCBI chr 1:205,569,014...205,602,918
Ensembl chr 1:205,568,885...205,602,918 		JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase IAGP DNA:hypermethylation:promoter (human) RGD PMID:17550320 RGD:2317632 NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983 		JBrowse link
G MIR155 microRNA 155 IEP miRNA:increased expression:serum RGD PMID:30653586 RGD:21081530 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044 		JBrowse link
G MIR192 microRNA 192 IEP RNA:increased expression:urine RGD PMID:26456596 RGD:41404678 NCBI chr11:64,891,137...64,891,246
Ensembl chr11:64,891,137...64,891,246 		JBrowse link
G MIR21 microRNA 21 IEP RNA:increased expression:urine RGD PMID:26456596 RGD:41404678 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G MIR23B microRNA 23b EXP CTD Direct Evidence: marker/mechanism CTD PMID:34418280 NCBI chr 9:95,085,208...95,085,304
Ensembl chr 9:95,085,208...95,085,304 		JBrowse link
G MIR494 microRNA 494 severity
exacerbates 		IEP
IMP 		RGD PMID:30314946 PMID:30314946 RGD:156420141, RGD:156420141 NCBI chr14:101,029,634...101,029,714
Ensembl chr14:101,029,634...101,029,714 		JBrowse link
G MKI67 marker of proliferation Ki-67 disease_progression IEP RGD PMID:12903495 RGD:2317705 NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423 		JBrowse link
G MMP2 matrix metallopeptidase 2 disease_progression ISO
IEP 		protein:increased expression:bile duct RGD PMID:15213623 PMID:19629755 RGD:2324667, RGD:2325769 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP9 matrix metallopeptidase 9 IEP
ISO 		mRNA:increased expression:bile duct
protein:increased expression:bile duct 		RGD PMID:16463672 PMID:15213623 PMID:15213623 RGD:2325856, RGD:2324667, RGD:2324667 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MSLN mesothelin EXP CTD Direct Evidence: marker/mechanism CTD PMID:14576474 NCBI chr16:760,734...768,865
Ensembl chr16:760,734...768,865 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase susceptibility IAGP DNA:polymorphism (human) RGD PMID:17201138 RGD:2317119 NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455 		JBrowse link
G MUC1 mucin 1, cell surface associated disease_progression IEP
ISO 		mRNA:increased expression:bile duct
protein:increased expression:bile duct:
protein:increased expression:serum
protein:increased secretion:bile 		RGD PMID:19639217 PMID:18081149 PMID:15213623 PMID:19260467 PMID:19055478 RGD:2317986, RGD:2324638, RGD:2324667, RGD:2324664, RGD:2324622 NCBI chr 1:155,185,824...155,192,915
Ensembl chr 1:155,185,824...155,192,916 		JBrowse link
G MUC16 mucin 16, cell surface associated IEP associated with Opisthorchiasis;protein:increased expression:serum RGD PMID:1653472 RGD:2325142 NCBI chr19:8,848,844...9,065,751
Ensembl chr19:8,848,844...9,010,390 		JBrowse link
G MUC2 mucin 2, oligomeric mucus/gel-forming IEP mRNA:decreased expression:bile duct RGD PMID:11680592 RGD:2324948 NCBI chr11:1,074,874...1,110,508
Ensembl chr11:1,074,875...1,110,511 		JBrowse link
G MUC3A mucin 3A, cell surface associated IEP mRNA:decreased expression:bile duct RGD PMID:11680592 RGD:2324948 NCBI chr 7:100,949,534...100,968,347
Ensembl chr 7:100,949,534...100,968,347 		JBrowse link
G MUC4 mucin 4, cell surface associated disease_progression IEP
ISO 		protein:increased expression:bile duct RGD PMID:14752841 PMID:19082442 RGD:2324944, RGD:2303602 NCBI chr 3:195,746,771...195,811,929
Ensembl chr 3:195,746,765...195,811,973 		JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming disease_progression IEP protein:increased expression:serum
mRNA:increased expression:bile duct 		RGD PMID:14508831 PMID:11680592 RGD:2324990, RGD:2324948 NCBI chr11:1,157,953...1,201,138
Ensembl chr11:1,157,953...1,201,138 		JBrowse link
G MUC5B mucin 5B, oligomeric mucus/gel-forming IEP mRNA:decreased expression:bile duct RGD PMID:11680592 RGD:2324948 NCBI chr11:1,223,066...1,262,172
Ensembl chr11:1,223,066...1,262,172 		JBrowse link
G MUC6 mucin 6, oligomeric mucus/gel-forming (gene/pseudogene) IEP protein:increased expression: : RGD PMID:10209489 RGD:2325167 NCBI chr11:1,012,823...1,036,718
Ensembl chr11:1,012,823...1,036,718 		JBrowse link
G NAT2 N-acetyltransferase 2 IAGP DNA:polymorphisms (human) RGD PMID:15901993 RGD:2317172 NCBI chr 8:18,386,301...18,401,218
Ensembl chr 8:18,391,282...18,401,218 		JBrowse link
G NCAM1 neural cell adhesion molecule 1 IEP associated with hepatitis RGD PMID:12031086 RGD:2326079 NCBI chr11:112,961,420...113,278,436
Ensembl chr11:112,961,275...113,278,436 		JBrowse link
G NOS2 nitric oxide synthase 2 IEP
EXP 		protein:increased expression:bile duct
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:16818635 PMID:16094703 RGD:2325280 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOTCH1 notch receptor 1 IEP protein:increased expression:cholangiocyte RGD PMID:15887117 RGD:2325330 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 disease_progression ISO mRNA:decreased expression:liver (rat) RGD PMID:24255171 RGD:15090822 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414 		JBrowse link
G OGG1 8-oxoguanine DNA glycosylase disease_progression IAGP DNA:loss of heterozygosity (human) RGD PMID:11866974 PMID:11260864 RGD:2317134, RGD:2317136 NCBI chr 3:9,749,952...9,783,108
Ensembl chr 3:9,749,944...9,788,219 		JBrowse link
G OSBP2 oxysterol binding protein 2 IEP mRNA:increased expression:blood RGD PMID:21763455 RGD:41404644 NCBI chr22:30,693,782...30,907,813
Ensembl chr22:30,693,782...30,907,824 		JBrowse link
G OSBPL7 oxysterol binding protein like 7 IEP mRNA:increased expression:blood RGD PMID:21763455 RGD:41404644 NCBI chr17:47,807,372...47,821,794
Ensembl chr17:47,807,372...47,821,803 		JBrowse link
G PACERR PTGS2 antisense NFKB1 complex-mediated expression regulator RNA IAGP ClinVar Annotator: match by term: Cholangiocarcinoma ClinVar NCBI chr 1:186,680,654...186,681,446
Ensembl chr 1:186,680,108...186,683,165 		JBrowse link
G PANX2 pannexin 2 disease_progression IEP mRNA:altered expression:liver (human) RGD PMID:31687280 RGD:152998978 NCBI chr22:50,170,731...50,180,295
Ensembl chr22:50,170,731...50,180,295 		JBrowse link
G PAWR pro-apoptotic WT1 regulator IEP mRNA,protein:decreased expression:cholangiocyte: RGD PMID:20724592 RGD:9835357 NCBI chr12:79,584,879...79,690,964
Ensembl chr12:79,574,979...79,690,964 		JBrowse link
G PBRM1 polybromo 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24185509 NCBI chr 3:52,545,367...52,685,913
Ensembl chr 3:52,545,352...52,685,917 		JBrowse link
G PEG3 paternally expressed 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22561520 NCBI chr19:56,810,082...56,840,726
Ensembl chr19:56,810,077...56,840,728 		JBrowse link
G PES1 pescadillo ribosomal biogenesis factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34845814 NCBI chr22:30,576,625...30,607,013
Ensembl chr22:30,576,625...30,607,083 		JBrowse link
G PIR pirin disease_progression IEP mRNA:altered expression:liver (human) RGD PMID:31687280 RGD:152998978 NCBI chr  X:15,384,799...15,493,333
Ensembl chr  X:15,384,799...15,493,564 		JBrowse link
G PPIA peptidylprolyl isomerase A ameliorates IMP human cell line and construct in a mouse model RGD PMID:21871105 RGD:150429623 NCBI chr 7:44,796,681...44,803,117
Ensembl chr 7:44,796,680...44,824,564 		JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha disease_progression IEP mRNA:altered expression:liver (human) RGD PMID:31687280 RGD:152998978 NCBI chr 4:101,023,418...101,347,526
Ensembl chr 4:101,023,409...101,348,278 		JBrowse link
G PREX2 phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 sexual_dimorphism IAGP DNA:substitutions, insertion/deletions: (human) RGD PMID:28000796 RGD:151665188 NCBI chr 8:67,952,046...68,237,032
Ensembl chr 8:67,952,046...68,237,032 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:26258846 NCBI chr19:14,091,688...14,117,762
Ensembl chr19:14,091,688...14,118,084 		JBrowse link
G PRKACB protein kinase cAMP-activated catalytic subunit beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:26258846 NCBI chr 1:84,078,079...84,238,498
Ensembl chr 1:84,078,062...84,238,498 		JBrowse link
G PRRG4 proline rich and Gla domain 4 disease_progression IEP mRNA:altered expression:liver (human) RGD PMID:31687280 RGD:152998978 NCBI chr11:32,829,789...32,858,120
Ensembl chr11:32,829,927...32,858,120 		JBrowse link
G PRSS2 serine protease 2 IEP protein:increased expression:serum RGD PMID:8621252 RGD:2324908 NCBI chr 7:142,770,970...142,774,560
Ensembl chr 7:142,760,398...142,774,564 		JBrowse link
G PRSS56 serine protease 56 disease_progression IEP mRNA:altered expression:liver (human) RGD PMID:31687280 RGD:152998978 NCBI chr 2:232,520,388...232,525,716
Ensembl chr 2:232,520,388...232,525,716 		JBrowse link
G PTEN phosphatase and tensin homolog ISO
EXP 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:27022031 PMID:23376645 RGD:12802341 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 IEP
IAGP
EXP 		protein:increased expression:bile duct
ClinVar Annotator: match by term: Cholangiocarcinoma
CTD Direct Evidence: marker/mechanism 		ClinVar
CTD
RGD		 PMID:16818635 PMID:19621664 RGD:2317180 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G RASSF8 Ras association domain family member 8 disease_progression IEP mRNA:altered expression:liver (human) RGD PMID:31687280 RGD:152998978 NCBI chr12:25,958,232...26,079,889
Ensembl chr12:25,958,232...26,079,892 		JBrowse link
G REG1A regenerating family member 1 alpha susceptibility IEP mRNA, protein:increased expression:liver (human) RGD PMID:11343228 RGD:10044031 NCBI chr 2:79,120,488...79,123,409
Ensembl chr 2:79,120,362...79,123,409 		JBrowse link
G RNF39 ring finger protein 39 disease_progression IEP mRNA:altered expression:liver (human) RGD PMID:31687280 RGD:152998978 NCBI chr 6:30,070,270...30,075,769
Ensembl chr 6:30,070,266...30,075,849 		JBrowse link
G RNF43 ring finger protein 43 exacerbates EXP
IAGP 		CTD Direct Evidence: marker/mechanism
associated with opisthorchiasis;DNA:SNPs:multiple: (human) 		CTD
RGD		 PMID:22561520 PMID:22561520 RGD:151361227 NCBI chr17:58,352,500...58,417,534
Ensembl chr17:58,353,676...58,417,595 		JBrowse link
G ROBO2 roundabout guidance receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22561520 NCBI chr 3:75,906,675...77,649,964
Ensembl chr 3:75,906,695...77,649,964 		JBrowse link
G RUNX3 RUNX family transcription factor 3 IEP protein:decreased expression:bile duct RGD PMID:19827872 RGD:2324955 NCBI chr 1:24,899,511...24,965,138
Ensembl chr 1:24,899,511...24,965,121 		JBrowse link
G SLC4A4 solute carrier family 4 member 4 disease_progression IEP mRNA:altered expression:liver (human) RGD PMID:31687280 RGD:152998978 NCBI chr 4:71,062,660...71,572,083
Ensembl chr 4:71,062,667...71,572,087 		JBrowse link
G SLC5A5 solute carrier family 5 member 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17408651 NCBI chr19:17,871,945...17,895,174
Ensembl chr19:17,871,945...17,895,174 		JBrowse link
G SLC7A5 solute carrier family 7 member 5 disease_progression
treatment 		IEP
IMP 		RGD PMID:25475870 PMID:28347255 PMID:24131658 RGD:151361214, RGD:151361294, RGD:151361287 NCBI chr16:87,830,023...87,869,507
Ensembl chr16:87,830,016...87,869,507 		JBrowse link
G SMAD4 SMAD family member 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22561520 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,528...51,085,045 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 severity IEP protein:decreased expression:bile duct (human) RGD PMID:26485275 RGD:11250478 NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077 		JBrowse link
G SOX17 SRY-box transcription factor 17 severity ISO RGD PMID:20816680 RGD:4889598 NCBI chr 8:54,457,935...54,460,892
Ensembl chr 8:54,457,935...54,460,892 		JBrowse link
G SOX2 SRY-box transcription factor 2 disease_progression IEP mRNA:altered expression:liver (human) RGD PMID:31687280 RGD:152998978 NCBI chr 3:181,711,925...181,714,436
Ensembl chr 3:181,711,925...181,714,436 		JBrowse link
G TGFB1 transforming growth factor beta 1 disease_progression IEP
ISO 		protein:increased expression:pancreas RGD PMID:16083599 PMID:12632524 RGD:2325020, RGD:1299231 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO mRNA:increased expression:bile duct RGD PMID:12632524 RGD:1299231 NCBI chr 3:30,606,356...30,694,142
Ensembl chr 3:30,606,478...30,694,249 		JBrowse link
G THBS1 thrombospondin 1 disease_progression IEP
IDA 		DNA:hypermethylation (human) RGD PMID:16465407 PMID:11927969 PMID:12213730 RGD:2325024, RGD:2325027, RGD:2325026 NCBI chr15:39,581,079...39,599,466
Ensembl chr15:39,581,079...39,599,466 		JBrowse link
G TNC tenascin C severity ISO RGD PMID:20816680 RGD:4889598 NCBI chr 9:115,019,575...115,118,157
Ensembl chr 9:115,019,575...115,118,207 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 severity IEP protein:increased expression:bile duct (human) RGD PMID:26485275 RGD:11250478 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
G TP53 tumor protein p53 ISO
EXP 		CTD Direct Evidence: marker/mechanism CTD PMID:16818635 PMID:22561520 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TTR transthyretin IEP protein:decreased expression:blood serum (human) RGD PMID:18275060 RGD:151660506 NCBI chr18:31,591,877...31,598,821
Ensembl chr18:31,557,009...31,598,833 		JBrowse link
G UGT1A9 UDP glucuronosyltransferase family 1 member A9 IEP RGD PMID:9230212 RGD:2325161 NCBI chr 2:233,671,898...233,773,300
Ensembl chr 2:233,671,898...233,773,300 		JBrowse link
G VEGFA vascular endothelial growth factor A IAGP ClinVar Annotator: match by term: Cholangiocarcinoma ClinVar PMID:18550579 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G WDHD1 WD repeat and HMG-box DNA binding protein 1 ameliorates IMP RGD PMID:30314946 RGD:156420141 NCBI chr14:54,938,949...55,027,099
Ensembl chr14:54,938,949...55,027,105 		JBrowse link
G WNT9A Wnt family member 9A disease_progression IEP mRNA:altered expression:liver (human) RGD PMID:31687280 RGD:152998978 NCBI chr 1:227,918,656...227,947,932
Ensembl chr 1:227,918,656...227,947,932 		JBrowse link
extrahepatic bile duct adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAP1 BRCA1 associated deubiquitinase 1 disease_progression IAGP RGD PMID:25536104 RGD:150340631 NCBI chr 3:52,401,008...52,410,008
Ensembl chr 3:52,401,008...52,410,008 		JBrowse link
G PBRM1 polybromo 1 disease_progression IAGP RGD PMID:25536104 RGD:150340631 NCBI chr 3:52,545,367...52,685,913
Ensembl chr 3:52,545,352...52,685,917 		JBrowse link
G RAC1 Rac family small GTPase 1 IEP protein:increased expression:mucosa (human) RGD PMID:21537609 RGD:153350126 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967 		JBrowse link
G SLC7A5 solute carrier family 7 member 5 disease_progression IEP RGD PMID:24890221 RGD:151361210 NCBI chr16:87,830,023...87,869,507
Ensembl chr16:87,830,016...87,869,507 		JBrowse link
extrahepatic bile duct carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PKD1 polycystin 1, transient receptor potential channel interacting IAGP ClinVar Annotator: match by term: Extrahepatic bile duct cancer ClinVar PMID:25741868 NCBI chr16:2,088,708...2,135,898
Ensembl chr16:2,088,708...2,135,898 		JBrowse link
G POLD1 DNA polymerase delta 1, catalytic subunit IAGP ClinVar Annotator: match by term: Extrahepatic bile duct cancer ClinVar PMID:25741868 PMID:26467025 PMID:28492532 NCBI chr19:50,384,323...50,418,018
Ensembl chr19:50,384,204...50,418,018 		JBrowse link
G XPO1 exportin 1 disease_progression IEP protein:increased expression:extrahepatic bile duct (human) RGD PMID:27279267 RGD:151665800 NCBI chr 2:61,477,849...61,538,612
Ensembl chr 2:61,476,032...61,538,741 		JBrowse link
fibrolamellar carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CA12 carbonic anhydrase 12 IEP mRNA:increased expression:liver RGD PMID:28304380 RGD:153352326 NCBI chr15:63,321,378...63,381,846
Ensembl chr15:63,321,378...63,381,846 		JBrowse link
G CTNNB1 catenin beta 1 IDA protein:increased tyrosine phosphorylation:exon: RGD PMID:19101982 RGD:14402052 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096 		JBrowse link
G FGFR1 fibroblast growth factor receptor 1 IEP protein:increased expression:liver: RGD PMID:24925055 RGD:11055933 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha IGI mRNA,protein:increased expression:liver (human) RGD PMID:27027723 RGD:151347845 NCBI chr19:14,091,688...14,117,762
Ensembl chr19:14,091,688...14,118,084 		JBrowse link
gallbladder adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme IAGP DNA:polymorphism: :rs4646994 (human) RGD PMID:20438364 RGD:2325207 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G CDK1 cyclin dependent kinase 1 IEP protein:increased expression:gallbladder RGD PMID:15017593 RGD:2722465 NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852 		JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 disease_progression IDA RGD PMID:29043607 RGD:150429712 NCBI chr 1:162,630,863...162,787,405
Ensembl chr 1:162,631,373...162,787,405 		JBrowse link
G IFITM1 interferon induced transmembrane protein 1 disease_progression IDA RGD PMID:29043607 RGD:150429712 NCBI chr11:314,040...315,272
Ensembl chr11:310,041...315,272 		JBrowse link
gallbladder cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APC APC regulator of WNT signaling pathway disease_progression IAGP DNA:SNP::rs11954856(human) RGD PMID:26715268 RGD:151356500 NCBI chr 5:112,707,498...112,846,239
Ensembl chr 5:112,707,518...112,846,239 		JBrowse link
G APOB apolipoprotein B susceptibility IAGP DNA:SNP: :rs693 (human) RGD PMID:17696941 PMID:20082485 RGD:2325764, RGD:2325761 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073 		JBrowse link
G APOE apolipoprotein E susceptibility IAGP DNA:SNP:intron:rs440446 (human) RGD PMID:18296645 RGD:2317550 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G AXIN2 axin 2 disease_progression IAGP DNA:SNP::s4791171(human) RGD PMID:26715268 RGD:151356500 NCBI chr17:65,528,563...65,561,648
Ensembl chr17:65,528,563...65,561,648 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase IAGP ClinVar Annotator: match by term: Gallbladder cancer ClinVar NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929 		JBrowse link
G BUB1B BUB1 mitotic checkpoint serine/threonine kinase B IEP mRNA:increased expression:gallbladder RGD PMID:18497548 RGD:2324871 NCBI chr15:40,161,069...40,221,123
Ensembl chr15:40,161,023...40,221,123 		JBrowse link
G CALR calreticulin exacerbates IEP mRNA, protein:increased expression:gall bladder (human) RGD PMID:33591948 RGD:150521682 NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 onset IAGP DNA:frameshift mutation:cds:p.S185_T195del rs333 (human) RGD PMID:18405329 RGD:2317570 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206 		JBrowse link
G CTNNB1 catenin beta 1 IAGP ClinVar Annotator: match by term: Gallbladder cancer ClinVar PMID:10435629 PMID:26822237 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096 		JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 susceptibility IAGP DNA:transition:5' utr:-34T>C rs743572 (human) RGD PMID:16381022 RGD:2317619 NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 IAGP DNA:transition: :6235T>C (human)
DNA:polymorphism: :p.I462V (human) 		RGD PMID:18287863 PMID:18990008 RGD:2317212, RGD:2317211 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G DPYD dihydropyrimidine dehydrogenase disease_progression IEP RGD PMID:16619549 RGD:2317631 NCBI chr 1:97,077,743...97,921,059
Ensembl chr 1:97,077,743...97,995,000 		JBrowse link
G EGF epidermal growth factor susceptibility IAGP
IEP 		DNA:SNP: :+61A>G (rs4444903)(human) RGD PMID:18571008 PMID:8093356 RGD:2317641, RGD:2317646 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G GLI1 GLI family zinc finger 1 disease_progression IAGP DNA:SNP::rs2228226(human) RGD PMID:26715268 RGD:151356500 NCBI chr12:57,459,785...57,472,268
Ensembl chr12:57,459,785...57,472,268 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 IEP RGD PMID:26925680 RGD:14700928 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit exacerbates IEP protein:increased expression:gall bladder (human) RGD PMID:26318166 RGD:11528126 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 IAGP DNA:missense mutations, frameshift mutations:cds:multiple (human) RGD PMID:18692501 RGD:6893398 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase IAGP ClinVar Annotator: match by term: Gallbladder cancer ClinVar PMID:6320174 PMID:11745231 PMID:15696205 PMID:16051643 PMID:17704260 More... NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936 		JBrowse link
G LOC126806658 BRD4-independent group 4 enhancer GRCh37_chr3:41265899-41267098 IAGP ClinVar Annotator: match by term: Gallbladder cancer ClinVar PMID:10435629 PMID:26822237 NCBI chr 3:41,224,408...41,225,607 JBrowse link
G LRP1B LDL receptor related protein 1B ameliorates IAGP DNA:mutations:multiple: (human) RGD PMID:32898339 RGD:150429787 NCBI chr 2:140,231,423...142,131,016
Ensembl chr 2:140,231,423...142,131,016 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha IAGP ClinVar Annotator: match by term: Gallbladder cancer ClinVar PMID:15520168 PMID:15608678 PMID:15930273 PMID:17673550 PMID:21078999 More... NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093 		JBrowse link
G RBP4 retinol binding protein 4 disease_progression IEP associated with type 2 diabetes mellitus; protein:decreased expression:blood serum (human) RGD PMID:37273108 RGD:329849105 NCBI chr10:93,591,694...93,601,744
Ensembl chr10:93,591,687...93,601,744 		JBrowse link
G RICTOR RPTOR independent companion of MTOR complex 2 IAGP DNA:CNV, amplification:exon (human) RGD PMID:24508317 RGD:152995522 NCBI chr 5:38,937,920...39,074,399
Ensembl chr 5:38,937,920...39,074,402 		JBrowse link
G SMAD4 SMAD family member 4 IAGP ClinVar Annotator: match by term: Gallbladder cancer ClinVar PMID:10479724 PMID:10764709 PMID:16152648 PMID:16436638 PMID:21465659 More... NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,528...51,085,045 		JBrowse link
G TP53 tumor protein p53 IAGP ClinVar Annotator: match by term: Gallbladder cancer ClinVar PMID:1631137 PMID:1978757 PMID:7478555 PMID:7791795 PMID:8023157 More... NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 susceptibility IAGP DNA:polymorphisms: :p.R194W, p.R399Q (human) RGD PMID:19266243 RGD:2317128 NCBI chr19:43,543,311...43,575,527
Ensembl chr19:43,543,311...43,580,473 		JBrowse link
gallbladder carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase IAGP RGD PMID:7795450 RGD:2317512 NCBI chr 9:133,250,401...133,275,201
Ensembl chr 9:133,233,278...133,276,024 		JBrowse link
G ACTR3 actin related protein 3 severity IEP Squamous Cell/Adenosquamous Carcinoma and Adenocarcinoma;protein:increased expression:gall bladder (human) RGD PMID:23320827 RGD:11571623 NCBI chr 2:113,889,934...113,962,596
Ensembl chr 2:113,890,063...113,962,596 		JBrowse link
G ANTXR1 ANTXR cell adhesion molecule 1 severity IEP RGD PMID:21545221 RGD:9684943 NCBI chr 2:69,013,144...69,249,327
Ensembl chr 2:69,013,176...69,249,327 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 exacerbates IEP mRNA:increased expression:gall bladder (human) RGD PMID:28295868 RGD:153297817 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403 		JBrowse link
G CFL1 cofilin 1 severity IEP Squamous Cell/Adenosquamous Carcinoma and Adenocarcinoma;protein:increased expression:gall bladder (human) RGD PMID:23320827 RGD:11571623 NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026 		JBrowse link
G CLPTM1L CLPTM1 like susceptibility IAGP DNA:SNP, haplotype: :rs401681(human) RGD PMID:29450669 RGD:150530629 NCBI chr 5:1,317,752...1,345,099
Ensembl chr 5:1,317,752...1,345,099 		JBrowse link
G GPX3 glutathione peroxidase 3 severity IEP protein:decreased expression:gallbladder (human) RGD PMID:24167362 RGD:151665515 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988 		JBrowse link
G IL10 interleukin 10 susceptibility IAGP associated with Cholelithiasis RGD PMID:19065724 RGD:2317654 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G MIR155 microRNA 155 disease_progression IEP miRNA:increased expression:gall bladder RGD PMID:26885061 RGD:21079444 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044 		JBrowse link
G MTUS1 microtubule associated scaffold protein 1 disease_progression IEP RGD PMID:31882471 RGD:25330344 NCBI chr 8:17,643,802...17,801,521
Ensembl chr 8:17,643,795...17,801,094 		JBrowse link
G PTCH1 patched 1 disease_progression IEP RGD PMID:22407314 RGD:150523794 NCBI chr 9:95,442,980...95,516,971
Ensembl chr 9:95,442,980...95,517,057 		JBrowse link
G RAC1 Rac family small GTPase 1 exacerbates IEP protein:increased expression:gallbladder (human) RGD PMID:21853342 RGD:155230819 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967 		JBrowse link
G TERT telomerase reverse transcriptase susceptibility IAGP DNA:SNP, haplotype: :rs2736100(human) RGD PMID:29450669 RGD:150530629 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068 		JBrowse link
G TGFA transforming growth factor alpha IEP RGD PMID:9542514 RGD:2317470 NCBI chr 2:70,447,284...70,553,826
Ensembl chr 2:70,447,284...70,554,193 		JBrowse link
G TJP1 tight junction protein 1 IEP protein:decreased expression:gallbladder RGD PMID:19184677 RGD:2325030 NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915 		JBrowse link
G TYMP thymidine phosphorylase disease_progression IEP RGD PMID:18946757 RGD:2325157 NCBI chr22:50,525,752...50,530,085
Ensembl chr22:50,525,752...50,530,032 		JBrowse link
G UBR5 ubiquitin protein ligase E3 component n-recognin 5 ameliorates IMP human cell line in a mouse model RGD PMID:30775814 RGD:151665192 NCBI chr 8:102,252,273...102,412,700
Ensembl chr 8:102,252,273...102,412,759 		JBrowse link
hepatoblastoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APC APC regulator of WNT signaling pathway IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:1316610 PMID:8381579 PMID:8764128 PMID:9824584 PMID:15311282 More... NCBI chr 5:112,707,498...112,846,239
Ensembl chr 5:112,707,518...112,846,239 		JBrowse link
G APOA1 apolipoprotein A1 IEP mRNA, protein:decreased expression:serum (human) RGD PMID:27974108 RGD:25671440 NCBI chr11:116,835,751...116,837,622
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G ARID1A AT-rich interaction domain 1A IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:26822237 NCBI chr 1:26,696,015...26,782,104
Ensembl chr 1:26,693,236...26,782,104 		JBrowse link
G ATM ATM serine/threonine kinase IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:11756177 PMID:16832357 PMID:17333338 PMID:19781682 PMID:20305132 More... NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102 		JBrowse link
G AXIN2 axin 2 IEP protein:increased expression:liver: RGD PMID:11809809 RGD:151356508 NCBI chr17:65,528,563...65,561,648
Ensembl chr17:65,528,563...65,561,648 		JBrowse link
G BARD1 BRCA1 associated RING domain 1 IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:26467025 PMID:26580448 PMID:28492532 PMID:35264596 More... NCBI chr 2:214,725,646...214,809,683
Ensembl chr 2:214,725,646...214,809,683 		JBrowse link
G BIVM-ERCC5 BIVM-ERCC5 readthrough IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar NCBI chr13:102,807,146...102,875,995
Ensembl chr13:102,799,110...102,875,994 		JBrowse link
G BRCA2 BRCA2 DNA repair associated IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:9971877 PMID:10717622 PMID:15937982 PMID:17826769 PMID:19941162 More... NCBI chr13:32,315,077...32,400,268
Ensembl chr13:32,315,086...32,400,268 		JBrowse link
G C11orf65 chromosome 11 open reading frame 65 IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:21665257 PMID:25085752 PMID:25186627 PMID:25741868 PMID:26787654 More... NCBI chr11:108,308,519...108,469,881
Ensembl chr11:108,308,519...108,467,531 		JBrowse link
G CDH1 cadherin 1 IEP protein:increased expression:liver RGD PMID:16465411 RGD:14402053 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537 		JBrowse link
G CLDN1 claudin 1 severity IEP mRNA,protein:decreased expression:liver, embryonic tissue (human) RGD PMID:16647953 RGD:26884349 NCBI chr 3:190,305,707...190,322,446
Ensembl chr 3:190,305,707...190,322,446 		JBrowse link
G COL7A1 collagen type VII alpha 1 chain IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:28492532 NCBI chr 3:48,564,073...48,595,329
Ensembl chr 3:48,564,073...48,595,329 		JBrowse link
G CTNNB1 catenin beta 1 IAGP
IEP
EXP 		ClinVar Annotator: match by term: Hepatoblastoma
protein:increased expression:cytoplasm,nucleus:
CTD Direct Evidence: marker/mechanism 		ClinVar
CTD
RGD		 PMID:9500465 PMID:9927029 PMID:10192393 PMID:10398436 PMID:10435629 More... RGD:14402054 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096 		JBrowse link
G DHCR7 7-dehydrocholesterol reductase IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:12270273 PMID:15670717 PMID:16207203 PMID:16392899 PMID:23042628 More... NCBI chr11:71,427,287...71,449,043
Ensembl chr11:71,428,193...71,452,868 		JBrowse link
G DIS3L2 DIS3 like 3'-5' exoribonuclease 2 IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:28492532 PMID:35495172 NCBI chr 2:231,961,713...232,344,350
Ensembl chr 2:231,961,245...232,344,350 		JBrowse link
G DOCK8 dedicator of cytokinesis 8 IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:28492532 NCBI chr 9:211,257...465,255
Ensembl chr 9:214,854...465,259 		JBrowse link
G DPEP1 dipeptidase 1 ameliorates IMP human cells in mouse model RGD PMID:31541079 RGD:153344539 NCBI chr16:89,613,308...89,641,540
Ensembl chr16:89,613,308...89,638,456 		JBrowse link
G DROSHA drosha ribonuclease III IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar NCBI chr 5:31,400,494...31,532,093
Ensembl chr 5:31,400,494...31,532,196 		JBrowse link
G EP300 E1A binding protein p300 IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:28492532 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,510...41,180,077 		JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:24728327 PMID:25741868 PMID:28492532 PMID:29178624 NCBI chr19:45,349,837...45,370,573
Ensembl chr19:45,349,837...45,370,918 		JBrowse link
G ERCC5 ERCC excision repair 5, endonuclease IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar NCBI chr13:102,846,032...102,875,995
Ensembl chr13:102,845,831...102,875,995 		JBrowse link
G EXT2 exostosin glycosyltransferase 2 IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar NCBI chr11:44,095,678...44,251,962
Ensembl chr11:44,095,648...44,251,962 		JBrowse link
G FAH fumarylacetoacetate hydrolase IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar NCBI chr15:80,152,789...80,186,949
Ensembl chr15:80,152,490...80,186,946 		JBrowse link
G FANCA FA complementation group A IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:24728327 PMID:25741868 PMID:26467025 PMID:28492532 NCBI chr16:89,737,549...89,816,647
Ensembl chr16:89,726,683...89,816,977 		JBrowse link
G FANCD2 FA complementation group D2 IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:28492532 PMID:28678401 PMID:30306255 NCBI chr 3:10,026,437...10,101,932
Ensembl chr 3:10,026,370...10,101,932 		JBrowse link
G FANCD2OS FANCD2 opposite strand IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:28492532 NCBI chr 3:10,081,320...10,108,457
Ensembl chr 3:10,081,317...10,108,255 		JBrowse link
G FANCM FA complementation group M IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:26467025 PMID:28492532 PMID:28678401 PMID:28881617 More... NCBI chr14:45,135,930...45,200,890
Ensembl chr14:45,135,930...45,200,890 		JBrowse link
G FAS Fas cell surface death receptor IEP
IAGP 		mRNA,protein:increased expression:hepatocyte:
ClinVar Annotator: match by term: Hepatoblastoma 		ClinVar
RGD		 PMID:28492532 PMID:10398166 RGD:14700699 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:28492532 PMID:35495172 NCBI chr 4:1,793,293...1,808,867
Ensembl chr 4:1,793,293...1,808,872 		JBrowse link
G FH fumarate hydratase IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:28492532 NCBI chr 1:241,497,603...241,519,755
Ensembl chr 1:241,497,511...241,519,799 		JBrowse link
G FLCN folliculin IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:26467025 PMID:28492532 PMID:35495172 NCBI chr17:17,212,212...17,237,330
Ensembl chr17:17,212,212...17,237,188 		JBrowse link
G FLNA filamin A IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:28492532 NCBI chr  X:154,348,531...154,374,634
Ensembl chr  X:154,348,524...154,374,634 		JBrowse link
G FRMPD1 FERM and PDZ domain containing 1 IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar NCBI chr 9:37,603,229...37,746,904
Ensembl chr 9:37,650,954...37,746,904 		JBrowse link
G GBA1 glucosylceramidase beta 1 IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:12204005 PMID:21228398 PMID:23430543 PMID:25741868 NCBI chr 1:155,234,452...155,244,627
Ensembl chr 1:155,234,452...155,244,699 		JBrowse link
G GLI3 GLI family zinc finger 3 IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:28492532 NCBI chr 7:41,960,949...42,264,268
Ensembl chr 7:41,960,949...42,264,100 		JBrowse link
G GPC3 glypican 3 IEP protein:increased expression:liver (human) RGD PMID:23530909 RGD:243065128 NCBI chr  X:133,535,745...133,985,594
Ensembl chr  X:133,535,745...133,987,100 		JBrowse link
G IGF2 insulin like growth factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23958494 NCBI chr11:2,129,117...2,149,566
Ensembl chr11:2,129,112...2,158,391 		JBrowse link
G JAG1 jagged canonical Notch ligand 1 IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:36965188 NCBI chr20:10,637,684...10,673,999
Ensembl chr20:10,637,684...10,673,999 		JBrowse link
G JMJD1C jumonji domain containing 1C IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:28492532 NCBI chr10:63,167,225...63,521,890
Ensembl chr10:63,167,221...63,521,850 		JBrowse link
G KDR kinase insert domain receptor IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:28492532 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595 		JBrowse link
G LOC106627981 GBA recombination region IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:12204005 PMID:21228398 PMID:23430543 PMID:25741868 NCBI chr 1:155,233,639...155,240,092 JBrowse link
G LOC107303338 3p25 FANCD2 Alu-mediated recombination region IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:28492532 PMID:28678401 PMID:30306255 NCBI chr 3:10,030,947...10,078,653 JBrowse link
G LOC126806658 BRD4-independent group 4 enhancer GRCh37_chr3:41265899-41267098 IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:9500465 PMID:9927029 PMID:10192393 PMID:10398436 PMID:10435629 More... NCBI chr 3:41,224,408...41,225,607 JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:27666373 PMID:28492532 NCBI chr 7:116,672,196...116,798,377
Ensembl chr 7:116,672,196...116,798,377 		JBrowse link
G MIR193A microRNA 193a exacerbates HEP RNA:decreased expression:liver (human) RGD PMID:31541079 RGD:153344539 NCBI chr17:31,559,996...31,560,083
Ensembl chr17:31,559,996...31,560,083 		JBrowse link
G MIR21 microRNA 21 IEP miRNA:increased expression:plasma, extracellular exosome RGD PMID:27601233 RGD:14695023 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G MIR34A microRNA 34a severity IEP miRNA:increased expression:liver RGD PMID:27046304 RGD:14695006 NCBI chr 1:9,151,668...9,151,777
Ensembl chr 1:9,151,668...9,151,777 		JBrowse link
G MKI67 marker of proliferation Ki-67 ameliorates IDA human cells in mouse model RGD PMID:31541079 RGD:153344539 NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423 		JBrowse link
G MSH2 mutS homolog 2 IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:28492532 NCBI chr 2:47,403,067...47,709,830
Ensembl chr 2:47,403,067...47,663,146 		JBrowse link
G MSH6 mutS homolog 6 IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:28492532 NCBI chr 2:47,783,145...47,810,101
Ensembl chr 2:47,695,530...47,810,063 		JBrowse link
G MUTYH mutY DNA glycosylase IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar NCBI chr 1:45,329,242...45,340,440
Ensembl chr 1:45,329,163...45,340,893 		JBrowse link
G NAP1L1 nucleosome assembly protein 1 like 1 IEP mRNA:increased expression:liver (human) RGD PMID:12935928 RGD:9590075 NCBI chr12:76,036,585...76,084,685
Ensembl chr12:76,036,585...76,084,735 		JBrowse link
G NDRG4 NDRG family member 4 IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar NCBI chr16:58,463,715...58,515,387
Ensembl chr16:58,462,846...58,513,628 		JBrowse link
G NYNRIN NYN domain and retroviral integrase containing IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar NCBI chr14:24,399,003...24,419,283
Ensembl chr14:24,399,003...24,419,283 		JBrowse link
G PCNA proliferating cell nuclear antigen EXP CTD Direct Evidence: marker/mechanism CTD PMID:11560253 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626 		JBrowse link
G RECQL RecQ like helicase IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar NCBI chr12:21,468,910...21,501,635
Ensembl chr12:21,468,910...21,501,669 		JBrowse link
G RECQL4 RecQ like helicase 4 IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:28492532 NCBI chr 8:144,511,288...144,517,833
Ensembl chr 8:144,511,288...144,517,845 		JBrowse link
G REN renin IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:28492532 NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324 		JBrowse link
G RHBDF2 rhomboid 5 homolog 2 IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar NCBI chr17:76,470,893...76,501,427
Ensembl chr17:76,470,891...76,501,790 		JBrowse link
G RPS19 ribosomal protein S19 IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:12586610 PMID:25741868 PMID:28492532 PMID:37897121 NCBI chr19:41,860,255...41,872,925
Ensembl chr19:41,860,255...41,872,925 		JBrowse link
G SALL1 spalt like transcription factor 1 IEP embryonal subtype;protein:increased expression:liver, nucleus (human) RGD PMID:23822878 RGD:11556217 NCBI chr16:51,135,982...51,152,334
Ensembl chr16:51,135,982...51,152,334 		JBrowse link
G SALL4 spalt like transcription factor 4 IEP Embryonal Hepatoblastoma;protein:increased expression:liver (human) RGD PMID:23822878 RGD:11556217 NCBI chr20:51,782,331...51,802,521
Ensembl chr20:51,782,331...51,802,521 		JBrowse link
G SH2B3 SH2B adaptor protein 3 IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:20404132 PMID:25741868 NCBI chr12:111,404,730...111,451,623
Ensembl chr12:111,405,923...111,451,623 		JBrowse link
G SLX4 SLX4 structure-specific endonuclease subunit IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:28492532 NCBI chr16:3,581,181...3,611,606
Ensembl chr16:3,581,181...3,611,606 		JBrowse link
G SMO smoothened, frizzled class receptor IEP protein:increased expression:liver RGD PMID:21159571 RGD:150521618 NCBI chr 7:129,188,633...129,213,545
Ensembl chr 7:129,188,633...129,213,545 		JBrowse link
G SPOP speckle type BTB/POZ protein IEP mRNA:decreased expression:liver (human) RGD PMID:24912477 RGD:153298925 NCBI chr17:49,598,884...49,678,163
Ensembl chr17:49,598,884...49,678,163 		JBrowse link
G STK11 serine/threonine kinase 11 IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:25741868 PMID:28492532 NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431 		JBrowse link
G TGFA transforming growth factor alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:11560253 NCBI chr 2:70,447,284...70,553,826
Ensembl chr 2:70,447,284...70,554,193 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar NCBI chr 3:30,606,356...30,694,142
Ensembl chr 3:30,606,478...30,694,249 		JBrowse link
G TP53 tumor protein p53 IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:1565143 PMID:8401536 PMID:8633021 PMID:12826609 PMID:17606709 More... NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor IAGP ClinVar Annotator: match by term: Hepatoblastoma ClinVar PMID:7563486 PMID:8634692 PMID:8707293 PMID:8772572 PMID:8956040 More... NCBI chr 3:10,141,778...10,153,667
Ensembl chr 3:10,141,778...10,153,676 		JBrowse link
G ZFHX3 zinc finger homeobox 3 IEP protein:increased expression:liver (human) RGD PMID:33368532 RGD:151361168 NCBI chr16:72,782,885...73,891,930
Ensembl chr16:72,782,885...73,891,871 		JBrowse link
hepatocellular carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2M alpha-2-macroglobulin ISO
EXP 		mRNA,protein:increased expression:liver:
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:15509519 PMID:15509519 RGD:1358261 NCBI chr12:9,067,708...9,116,229
Ensembl chr12:9,067,664...9,116,229 		JBrowse link
G AADAT aminoadipate aminotransferase EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:170,060,222...170,094,292
Ensembl chr 4:170,060,222...170,091,699 		JBrowse link
G ABCA1 ATP binding cassette subfamily A member 1 severity ISO
IEP 		mRNA:decreased expression:liver (human) RGD PMID:16941710 PMID:30580964 RGD:1598532, RGD:24922199 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155 		JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 susceptibility ISO
IAGP
EXP 		DNA:polymorphism: :c.3751G>A(human)
DNA:polymorphism: : c.1465C > T(human)
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:17510421 PMID:25625052 PMID:24175826 PMID:23488625 RGD:11041138, RGD:14700905, RGD:14700904 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCB4 ATP binding cassette subfamily B member 4 EXP
ISS 		CTD Direct Evidence: marker/mechanism
OMIM:114550 		CTD
MouseDO		 PMID:22022477 NCBI chr 7:87,365,896...87,476,027
Ensembl chr 7:87,401,696...87,480,435 		JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 ISO mRNA:increased expression:liver RGD PMID:25842354 RGD:11535155 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253 		JBrowse link
G ABCE1 ATP binding cassette subfamily E member 1 IEP mRNA:increased expression:liver (human) RGD PMID:21932399 RGD:11041873 NCBI chr 4:145,098,311...145,129,524
Ensembl chr 4:145,098,288...145,129,524 		JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO RGD PMID:32171747 RGD:126907997 NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,043...130,887,675 		JBrowse link
G ACACA acetyl-CoA carboxylase alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr17:37,084,992...37,406,836
Ensembl chr17:37,084,992...37,406,836 		JBrowse link
G ACE angiotensin I converting enzyme susceptibility EXP
IAGP 		CTD Direct Evidence: therapeutic
DNA:insertion/deletion:intron 16: 		CTD
RGD		 PMID:16328049 PMID:25208933 RGD:11343535 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ACER3 alkaline ceramidase 3 disease_progression IEP RGD PMID:30097213 RGD:35673325 NCBI chr11:76,860,918...77,026,797
Ensembl chr11:76,860,859...77,026,797 		JBrowse link
G ACLY ATP citrate lyase EXP CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr17:41,866,917...41,930,545
Ensembl chr17:41,866,917...41,930,542 		JBrowse link
G ACO2 aconitase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr22:41,469,117...41,528,974
Ensembl chr22:41,447,830...41,529,273 		JBrowse link
G ACOX1 acyl-CoA oxidase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12771043 PMID:15565109 NCBI chr17:75,941,507...75,979,166
Ensembl chr17:75,941,507...75,979,177 		JBrowse link
G ACSL4 acyl-CoA synthetase long chain family member 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr  X:109,641,335...109,733,257
Ensembl chr  X:109,624,244...109,733,403 		JBrowse link
G ACTB actin beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:19363144 PMID:21472284 NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902 		JBrowse link
G ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19514085 NCBI chr21:26,835,755...26,845,409
Ensembl chr21:26,835,755...26,845,409 		JBrowse link
G ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif 13 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:133,414,337...133,459,386
Ensembl chr 9:133,414,358...133,459,402 		JBrowse link
G ADD1 adducin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr 4:2,843,844...2,930,062
Ensembl chr 4:2,843,844...2,930,076 		JBrowse link
G ADGRG7 adhesion G protein-coupled receptor G7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:100,609,601...100,695,479
Ensembl chr 3:100,609,601...100,695,479 		JBrowse link
G ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:99,123,658...99,144,297
Ensembl chr 4:99,123,657...99,157,792 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing susceptibility IAGP DNA:SNP:intron:+276T>G (rs1501299) (human) RGD PMID:23740135 RGD:14401720 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G ADRA1A adrenoceptor alpha 1A EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:26,748,150...26,867,379
Ensembl chr 8:26,748,150...26,867,278 		JBrowse link
G ADRA2B adrenoceptor alpha 2B EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:96,112,876...96,116,571
Ensembl chr 2:96,112,876...96,116,571 		JBrowse link
G AFP alpha fetoprotein severity
treatment
disease_progression 		IEP
ISO
EXP 		protein:increased expression:serum (human)
CTD Direct Evidence: marker/mechanism
associated with hepatitis B 		CTD
RGD		 PMID:9029167 PMID:15276417 PMID:24012840 PMID:28284560 PMID:32961231 More... RGD:14401581, RGD:152177911, RGD:125097525, RGD:126790583, RGD:126790579 NCBI chr 4:73,436,221...73,456,174
Ensembl chr 4:73,431,138...73,456,174 		JBrowse link
G AICDA activation induced cytidine deaminase ISO RGD PMID:18997814 RGD:127285629 NCBI chr12:8,602,170...8,612,859
Ensembl chr12:8,602,155...8,613,242 		JBrowse link
G AK3 adenylate kinase 3 IEP protein:decreased expression:liver RGD PMID:17203974 RGD:13842477 NCBI chr 9:4,709,556...4,742,043
Ensembl chr 9:4,709,556...4,742,043 		JBrowse link
G AKR1A1 aldo-keto reductase family 1 member A1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:32805337 NCBI chr 1:45,550,826...45,570,049
Ensembl chr 1:45,550,543...45,570,049 		JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B IEP
ISO 		protein:increased expression:liver (human)
protein:increased expression:liver (rat) 		RGD PMID:19422879 PMID:21683810 RGD:8548685, RGD:5509919 NCBI chr 7:134,442,350...134,459,239
Ensembl chr 7:134,442,356...134,459,284 		JBrowse link
G AKR1B10 aldo-keto reductase family 1 member B10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 7:134,527,567...134,541,412
Ensembl chr 7:134,527,567...134,541,412 		JBrowse link
G AKR1C2 aldo-keto reductase family 1 member C2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr10:4,987,775...5,018,000
Ensembl chr10:4,987,775...5,018,031 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 exacerbates
treatment 		EXP
IEP
ISO 		CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver 		CTD
RGD		 PMID:32045588 PMID:37460115 PMID:25999787 PMID:31801250 RGD:408364960, RGD:152177911, RGD:151893509 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G AKT2 AKT serine/threonine kinase 2 ISO protein:increased phosphorylation:liver cancer cell (rat)
protein:increased phosphorylation:liver (mouse) 		RGD PMID:19309364 PMID:28100771 RGD:2313299, RGD:127285675 NCBI chr19:40,230,317...40,285,345
Ensembl chr19:40,230,317...40,285,536 		JBrowse link
G ALB albumin susceptibility IDA
IEP 		protein:decreased expression:serum (human)
associated with hepatitis C;protein:decreased expression:serum 		RGD PMID:23892757 PMID:22392353 PMID:29040987 RGD:11035269, RGD:125097525, RGD:14694841 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member susceptibility
no_association
severity 		IAGP
IEP 		associated with alcoholic liver cirrhosis;DNA:missense mutation:cds:p.E487K (human)
associated with alcohol use disorder;DNA:missense mutation:cds: (human)
DNA:missense mutation:exon 12: (human)
associated with hepatitis B;DNA;missense mutation, haplotype:cds: (rs671) (human)
DNA:missense mutation:cds: (rs671) (human)
mRNA, protein:decreased expression:liver (human)
protein:decreased expression: liver (human)
associated with hepatitis C:DNA:SNP:exon 12 (human)
DNA:missense mutation:cds, exon 12:p.E487K (human) 		RGD PMID:25778454 PMID:18439068 PMID:10737710 PMID:26827895 PMID:29765251 More... RGD:11054822, RGD:15042862, RGD:15042859, RGD:15042857, RGD:14700899, RGD:15036809, RGD:14696779, RGD:14696778, RGD:14696699 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532 		JBrowse link
G ALDH7A1 aldehyde dehydrogenase 7 family member A1 severity IEP mRNA:altered expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr 5:126,541,841...126,595,219
Ensembl chr 5:126,531,200...126,595,362 		JBrowse link
G ALDOC aldolase, fructose-bisphosphate C ISO mRNA:increased expression:liver RGD PMID:3830170 RGD:2301136 NCBI chr17:28,573,120...28,576,895
Ensembl chr17:28,573,115...28,576,948 		JBrowse link
G ALX4 ALX homeobox 4 ameliorates IEP
IDA
ISO 		mRNA, protein:decreased expression:liver RGD PMID:28081728 PMID:31132711 PMID:31132711 RGD:153323329, RGD:153323330, RGD:153323330 NCBI chr11:44,260,440...44,310,139
Ensembl chr11:44,260,440...44,310,139 		JBrowse link
G ANGPTL6 angiopoietin like 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr19:10,092,338...10,106,190
Ensembl chr19:10,092,338...10,102,678 		JBrowse link
G ANK3 ankyrin 3 ISO protein:decreased expression:liver RGD PMID:26652480 RGD:153344559 NCBI chr10:60,026,298...60,733,528
Ensembl chr10:60,026,298...60,733,490 		JBrowse link
G ANLN anillin, actin binding protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:36,389,862...36,453,791
Ensembl chr 7:36,389,821...36,453,791 		JBrowse link
G ANTXR1 ANTXR cell adhesion molecule 1 treatment ISO RGD PMID:20650339 RGD:9684932 NCBI chr 2:69,013,144...69,249,327
Ensembl chr 2:69,013,176...69,249,327 		JBrowse link
G ANXA10 annexin A10 disease_progression IEP mRNA:decreased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr 4:168,092,537...168,187,736
Ensembl chr 4:168,092,537...168,187,736 		JBrowse link
G ANXA2 annexin A2 IEP mRNA, protein:increased expression:liver (human) RGD PMID:33675609 RGD:152999436 NCBI chr15:60,347,151...60,397,986
Ensembl chr15:60,347,134...60,402,883 		JBrowse link
G ANXA4 annexin A4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 2:69,643,808...69,827,112
Ensembl chr 2:69,644,425...69,827,112 		JBrowse link
G ANXA6 annexin A6 disease_progression IEP associated with tumor vascularization; protein:decreased expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr 5:151,100,706...151,157,779
Ensembl chr 5:151,100,706...151,157,815 		JBrowse link
G APC APC regulator of WNT signaling pathway IAGP
ISS
EXP
IDA 		ClinVar Annotator: match by term: Hepatocellular carcinoma
ClinVar Annotator: match by term: Hepatocellular cancer
ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma
OMIM:114550
CTD Direct Evidence: marker/mechanism
DNA:hypermethylation 		ClinVar
MouseDO
CTD
OMIM
RGD		 PMID:1316610 PMID:8381579 PMID:8381580 PMID:8395941 PMID:9101302 More... RGD:14402050 NCBI chr 5:112,707,498...112,846,239
Ensembl chr 5:112,707,518...112,846,239 		JBrowse link
G APCS amyloid P component, serum EXP CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr 1:159,587,826...159,588,865
Ensembl chr 1:159,587,826...159,588,865 		JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 treatment EXP
ISO 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:25109342 PMID:33841550 RGD:152998960 NCBI chr14:20,455,226...20,457,767
Ensembl chr14:20,455,191...20,457,772 		JBrowse link
G APLN apelin EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:129,645,259...129,654,956
Ensembl chr  X:129,645,259...129,654,956 		JBrowse link
G APOA1 apolipoprotein A1 disease_progression EXP
IEP 		CTD Direct Evidence: marker/mechanism
associated with hepatitis B;
protein:decreased expression:plasma (human) 		CTD
RGD		 PMID:21472284 PMID:31211449 PMID:23935864 RGD:153350082, RGD:25671438 NCBI chr11:116,835,751...116,837,622
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G APOA2 apolipoprotein A2 IEP associated with hepatitis B; mRNA:increased expression:liver RGD PMID:31211449 RGD:153350082 NCBI chr 1:161,222,292...161,223,628
Ensembl chr 1:161,222,290...161,223,631 		JBrowse link
G APOA4 apolipoprotein A4 disease_progression IEP associated with hepatitis B; RGD PMID:31211449 RGD:153350082 NCBI chr11:116,820,700...116,823,304
Ensembl chr11:116,820,700...116,823,304 		JBrowse link
G APOC1 apolipoprotein C1 disease_progression IEP associated with hepatitis B; RGD PMID:31211449 RGD:153350082 NCBI chr19:44,914,325...44,919,346
Ensembl chr19:44,914,247...44,919,349 		JBrowse link
G APOC2 apolipoprotein C2 IEP associated with hepatitis B; mRNA:increased expression:liver RGD PMID:31211449 RGD:153350082 NCBI chr19:44,946,051...44,949,565
Ensembl chr19:44,946,035...44,949,565 		JBrowse link
G APOC3 apolipoprotein C3 susceptibility
disease_progression 		IAGP
IEP 		associated with Chronic Hepatitis B;DNA:SNP: :rs2854116(human)
associated with hepatitis B; 		RGD PMID:27547913 PMID:31211449 RGD:153344620, RGD:153350082 NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072 		JBrowse link
G APOC4 apolipoprotein C4 disease_progression IEP associated with hepatitis B; RGD PMID:31211449 RGD:153350082 NCBI chr19:44,942,237...44,945,496
Ensembl chr19:44,942,237...44,945,496 		JBrowse link
G APOE apolipoprotein E ISO protein:increased expression:liver, serum (mouse) RGD PMID:21644509 RGD:6903288 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G APOF apolipoprotein F EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:56,360,568...56,362,857
Ensembl chr12:56,360,568...56,362,857 		JBrowse link
G APRT adenine phosphoribosyltransferase ISO protein:increased activity:hepatoma (rat) RGD PMID:6327016 RGD:5135035 NCBI chr16:88,809,339...88,811,928
Ensembl chr16:88,809,339...88,811,937 		JBrowse link
G AR androgen receptor EXP CTD Direct Evidence: therapeutic CTD PMID:18639551 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619 		JBrowse link
G ARG1 arginase 1 disease_progression IDA
IEP 		associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human) RGD PMID:17210712 PMID:30901224 RGD:4140476, RGD:152995286 NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332 		JBrowse link
G ARHGAP11A Rho GTPase activating protein 11A EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:32,615,144...32,639,941
Ensembl chr15:32,615,144...32,639,941 		JBrowse link
G ARHGAP44 Rho GTPase activating protein 44 exacerbates IEP protein:decreased expression:liver (human) RGD PMID:31136984 RGD:401901276 NCBI chr17:12,789,498...12,991,643
Ensembl chr17:12,789,498...12,991,643 		JBrowse link
G ARHGEF39 Rho guanine nucleotide exchange factor 39 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:35,659,343...35,665,195
Ensembl chr 9:35,658,875...35,675,866 		JBrowse link
G ARID1A AT-rich interaction domain 1A exacerbates
treatment 		EXP
ISO
IMP
IEP 		CTD Direct Evidence: marker/mechanism
human gene in mouse model
associated with non-alcoholic steatohepatitis
mRNA, protein:decreased expression:liver (human)
mRNA, protein:increased expression:liver (human) 		CTD
RGD		 PMID:22561517 PMID:22634756 PMID:22922871 PMID:29136504 PMID:29136504 More... RGD:126790634, RGD:126790634, RGD:11344640, RGD:125097519, RGD:125097495, RGD:125097485 NCBI chr 1:26,696,015...26,782,104
Ensembl chr 1:26,693,236...26,782,104 		JBrowse link
G ARID1B AT-rich interaction domain 1B EXP CTD Direct Evidence: marker/mechanism CTD PMID:22634756 NCBI chr 6:156,776,026...157,210,779
Ensembl chr 6:156,776,020...157,210,779 		JBrowse link
G ARID2 AT-rich interaction domain 2 disease_progression
exacerbates 		EXP
IDA
IEP
IMP 		CTD Direct Evidence: marker/mechanism
associated with hepatitis B;protein:decreased expression:liver 		CTD
RGD		 PMID:21822264 PMID:22634756 PMID:25701229 PMID:28498550 PMID:27351279 More... RGD:150429631, RGD:150340712, RGD:150340711, RGD:150340708 NCBI chr12:45,729,706...45,908,037
Ensembl chr12:45,729,706...45,908,040 		JBrowse link
G ARID3A AT-rich interaction domain 3A EXP CTD Direct Evidence: marker/mechanism CTD PMID:35179300 NCBI chr19:925,732...975,939
Ensembl chr19:925,781...975,939 		JBrowse link
G ARRB2 arrestin beta 2 treatment ISO RGD PMID:33841550 RGD:152998960 NCBI chr17:4,710,632...4,721,497
Ensembl chr17:4,710,596...4,721,499 		JBrowse link
G ASF1B anti-silencing function 1B histone chaperone EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr19:14,119,512...14,136,589
Ensembl chr19:14,119,512...14,136,613 		JBrowse link
G ASL argininosuccinate lyase disease_progression IEP associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr 7:66,075,819...66,093,576
Ensembl chr 7:66,075,800...66,094,697 		JBrowse link
G ASNS asparagine synthetase (glutamine-hydrolyzing) ISO protein:increased activity:serum (rat) RGD PMID:10081 RGD:2316006 NCBI chr 7:97,851,677...97,928,441
Ensembl chr 7:97,851,677...97,872,542 		JBrowse link
G ASPG asparaginase EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:104,085,700...104,115,582
Ensembl chr14:104,085,686...104,115,582 		JBrowse link
G ASPM assembly factor for spindle microtubules disease_progression IEP
EXP 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:28284560 PMID:18676753 RGD:13439743 NCBI chr 1:197,084,127...197,146,669
Ensembl chr 1:197,084,121...197,146,694 		JBrowse link
G ASS1 argininosuccinate synthase 1 disease_progression IMP
IEP 		associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human) RGD PMID:12359751 PMID:30901224 RGD:4140479, RGD:152995286 NCBI chr 9:130,444,707...130,501,274
Ensembl chr 9:130,444,961...130,501,274 		JBrowse link
G ATG101 autophagy related 101 disease_progression IEP RGD PMID:35592424 RGD:153350091 NCBI chr12:52,065,300...52,077,495
Ensembl chr12:52,069,246...52,077,495 		JBrowse link
G ATG7 autophagy related 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:29191453 NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665 		JBrowse link
G ATM ATM serine/threonine kinase exacerbates EXP
HEP 		CTD Direct Evidence: marker/mechanism
protein:increased expression:liver (human) 		CTD
RGD		 PMID:19919837 PMID:12866955 RGD:126781750 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102 		JBrowse link
G ATP5PB ATP synthase peripheral stalk-membrane subunit b IEP associated with hepatitis C RGD PMID:18932288 RGD:14696822 NCBI chr 1:111,449,464...111,462,773
Ensembl chr 1:111,448,864...111,462,773 		JBrowse link
G ATP5PD ATP synthase peripheral stalk subunit d EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr17:75,038,863...75,046,969
Ensembl chr17:75,038,863...75,046,985 		JBrowse link
G AURKA aurora kinase A EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:56,369,390...56,392,215
Ensembl chr20:56,369,389...56,392,337 		JBrowse link
G AURKB aurora kinase B EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:8,204,731...8,210,575
Ensembl chr17:8,204,733...8,210,600 		JBrowse link
G AXIN1 axin 1 disease_progression IAGP
IEP
ISO
EXP 		ClinVar Annotator: match by term: AXIN1-related condition | ClinVar Annotator: match by term: Hepatocellular cancer
ClinVar Annotator: match by term: Hepatocellular carcinoma
protein:decreased expression:liver (human)
associated with Hepatitis B, Chronic,DNA:SNP, haplotype:exon:(rs1805105) T>C (human)
CTD Direct Evidence: marker/mechanism 		ClinVar
CTD
OMIM
RGD		 PMID:10700176 PMID:25741868 PMID:25822088 PMID:28492532 PMID:37582359 More... RGD:1300371, RGD:150530482, RGD:150530481, RGD:14402039 NCBI chr16:287,440...352,723
Ensembl chr16:287,440...352,723 		JBrowse link
G AXIN2 axin 2 IEP protein:increased expression:liver: RGD PMID:11809809 RGD:151356508 NCBI chr17:65,528,563...65,561,648
Ensembl chr17:65,528,563...65,561,648 		JBrowse link
G AZGP1 alpha-2-glycoprotein 1, zinc-binding disease_progression IEP
ISO
HEP 		mRNA:decreased expression:liver
associated with hepatitis B;mRNA:decreased expression:liver 		RGD PMID:22625427 PMID:26902423 PMID:26902423 PMID:27993894 RGD:153350130, RGD:153350133, RGD:153350133, RGD:153350132 NCBI chr 7:99,966,730...99,976,031
Ensembl chr 7:99,966,720...99,976,042 		JBrowse link
G AZIN1 antizyme inhibitor 1 disease_progression IDA RNA:increased editing:liver RGD PMID:23291631 RGD:14700705 NCBI chr 8:102,826,302...102,864,200
Ensembl chr 8:102,826,111...102,893,864 		JBrowse link
G BANF1 barrier to autointegration nuclear assembly factor 1 treatment ISO
IEP 		mRNA, protein:increased expression:liver (rat)
mRNA, protein:increased expression:liver (human) 		RGD PMID:29059470 PMID:29059470 PMID:29059470 RGD:155791679, RGD:155791679, RGD:155791679 NCBI chr11:66,002,079...66,004,149
Ensembl chr11:66,002,228...66,004,149 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator treatment ISO RGD PMID:33841550 RGD:152998960 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO mRNA:increased expression:liver (mouse) RGD PMID:28100771 PMID:33841550 RGD:127285675, RGD:152998960 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L1 BCL2 like 1 treatment EXP
ISO 		CTD Direct Evidence: marker/mechanism|therapeutic
mRNA:increased expression:liver (mouse) 		CTD
RGD		 PMID:10629087 PMID:11509945 PMID:33841550 PMID:28100771 RGD:152998960, RGD:127285675 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BCO2 beta-carotene oxygenase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:112,175,512...112,218,946
Ensembl chr11:112,175,510...112,224,699 		JBrowse link
G BCORL1 BCL6 corepressor like 1 disease_progression IEP RGD PMID:29679906 PMID:26879601 RGD:150340705, RGD:11556159 NCBI chr  X:129,980,313...130,058,071
Ensembl chr  X:129,981,107...130,058,071 		JBrowse link
G BHMT betaine--homocysteine S-methyltransferase disease_progression IEP associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr 5:79,111,809...79,132,288
Ensembl chr 5:79,111,809...79,132,288 		JBrowse link
G BHMT2 betaine--homocysteine S-methyltransferase 2 severity IEP mRNA:altered expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr 5:79,069,767...79,090,069
Ensembl chr 5:79,069,767...79,090,069 		JBrowse link
G BID BH3 interacting domain death agonist EXP CTD Direct Evidence: marker/mechanism CTD PMID:15289866 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 ameliorates
treatment
exacerbates 		IMP
IDA
IEP 		human cell line in a mouse model
mRNA, protein:increased expression:liver (human)
associated with hepatitis B;mRNA, protein:increased expression:liver (human) 		RGD PMID:30368883 PMID:30210622 PMID:33310033 PMID:22820591 PMID:22682366 RGD:152998937, RGD:152999010, RGD:152998988, RGD:152998986, RGD:152998984 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 disease_progression EXP
HEP 		CTD Direct Evidence: marker/mechanism|therapeutic
mRNA:increased expression:liver (human) 		CTD
RGD		 PMID:16086872 PMID:20514400 PMID:31964418 RGD:153344516 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636 		JBrowse link
G BIRC7 baculoviral IAP repeat containing 7 exacerbates HEP mRNA:increased expression:liver (human) RGD PMID:31964418 RGD:153344516 NCBI chr20:63,235,905...63,240,495
Ensembl chr20:63,235,883...63,240,495 		JBrowse link
G BLZF1 basic leucine zipper nuclear factor 1 disease_progression IEP RGD PMID:26342799 RGD:14398326 NCBI chr 1:169,368,195...169,396,575
Ensembl chr 1:169,367,970...169,396,540 		JBrowse link
G BMI1 BMI1 proto-oncogene, polycomb ring finger treatment IMP RGD PMID:26919246 RGD:14928318 NCBI chr10:22,321,099...22,331,706
Ensembl chr10:22,321,099...22,331,484 		JBrowse link
G BMPER BMP binding endothelial regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:33,904,915...34,156,427
Ensembl chr 7:33,904,308...34,156,427 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:27222248 NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929 		JBrowse link
G BSG basigin (Ok blood group) EXP CTD Direct Evidence: marker/mechanism CTD PMID:36574092 NCBI chr19:571,283...583,493
Ensembl chr19:571,277...583,494 		JBrowse link
G BTG2 BTG anti-proliferation factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18393292 NCBI chr 1:203,305,519...203,309,602
Ensembl chr 1:203,305,491...203,309,602 		JBrowse link
G BUB1 BUB1 mitotic checkpoint serine/threonine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:110,637,528...110,678,063
Ensembl chr 2:110,637,528...110,678,063 		JBrowse link
G BUB1B BUB1 mitotic checkpoint serine/threonine kinase B EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:40,161,069...40,221,123
Ensembl chr15:40,161,023...40,221,123 		JBrowse link
G C14orf180 chromosome 14 open reading frame 180 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:104,579,764...104,590,515
Ensembl chr14:104,579,764...104,590,515 		JBrowse link
G C3 complement C3 ISO RGD PMID:23245919 RGD:11040806 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G C9 complement C9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19363144 PMID:28284560 NCBI chr 5:39,284,140...39,364,495
Ensembl chr 5:39,284,140...39,371,324 		JBrowse link
G CA12 carbonic anhydrase 12 disease_progression
ameliorates 		IEP
ISO 		mRNA:altered expression:liver RGD PMID:35362480 PMID:29900055 PMID:31934040 PMID:35362480 RGD:153352325, RGD:155226869, RGD:153352328, RGD:153352325 NCBI chr15:63,321,378...63,381,846
Ensembl chr15:63,321,378...63,381,846 		JBrowse link
G CA2 carbonic anhydrase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 8:85,464,007...85,481,493
Ensembl chr 8:85,463,968...85,481,493 		JBrowse link
G CA9 carbonic anhydrase 9 IEP mRNA:altered expression:liver RGD PMID:29900055 RGD:155226869 NCBI chr 9:35,673,928...35,681,159
Ensembl chr 9:35,673,928...35,681,159 		JBrowse link
G CAB39 calcium binding protein 39 disease_progression IEP
IMP 		RGD PMID:28605041 PMID:28605041 RGD:14398832, RGD:14398832 NCBI chr 2:230,712,842...230,821,075
Ensembl chr 2:230,712,842...230,821,075 		JBrowse link
G CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase ISO DNA:amplification:cds (rat)
mRNA:increased expression:liver 		RGD PMID:2914957 PMID:7053379 PMID:2888462 RGD:5132587, RGD:10755426, RGD:2303530 NCBI chr 2:27,217,369...27,243,943
Ensembl chr 2:27,217,369...27,243,943 		JBrowse link
G CADM1 cell adhesion molecule 1 ISO DNA, mRNA, protein:hypermethylation, decreased expression:promoter, liver RGD PMID:17428255 RGD:2289095 NCBI chr11:115,169,236...115,504,415
Ensembl chr11:115,169,218...115,504,957 		JBrowse link
G CADM2 cell adhesion molecule 2 disease_progression IEP mRNA, protein:decreased expression:liver RGD PMID:24240726 RGD:15092075 NCBI chr 3:84,958,989...86,074,429
Ensembl chr 3:84,958,989...86,074,429 		JBrowse link
G CALML3 calmodulin like 3 severity HEP protein:decreased expression:liver (human) RGD PMID:29445139 RGD:151665319 NCBI chr10:5,524,961...5,526,771
Ensembl chr10:5,524,961...5,526,771 		JBrowse link
G CALR calreticulin exacerbates
treatment 		IEP
IMP
IDA 		protein:increased expression:liver (human)
human cells and recombinant gene in a mouse model 		RGD PMID:27055635 PMID:24997628 PMID:12096119 RGD:150521681, RGD:150521691, RGD:150521690 NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489 		JBrowse link
G CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 IEP RGD PMID:23651211 RGD:18337283 NCBI chr 1:20,482,391...20,486,210
Ensembl chr 1:20,482,391...20,486,210 		JBrowse link
G CAP2 cyclase associated actin cytoskeleton regulatory protein 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:17,393,595...17,557,780
Ensembl chr 6:17,393,595...17,557,780 		JBrowse link
G CAPN3 calpain 3 ISO mRNA:decreased expression:skeletal muscle RGD PMID:10806331 RGD:1600777 NCBI chr15:42,359,501...42,412,317
Ensembl chr15:42,359,498...42,412,949 		JBrowse link
G CARM1 coactivator associated arginine methyltransferase 1 ISO mRNA,protein:increased expression:liver: RGD PMID:23912631 RGD:9586718 NCBI chr19:10,871,553...10,923,075
Ensembl chr19:10,871,553...10,923,075 		JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:29133031 PMID:33841550 RGD:13782296, RGD:152998960 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP8 caspase 8 severity
treatment 		IAGP
EXP
ISO 		CTD Direct Evidence: marker/mechanism
associated with hepatitis B;DNA:insertion/deletion:promoter: (rs3834129) (human) 		OMIM
CTD
RGD		 PMID:28643196 PMID:29133031 RGD:14695027, RGD:13782296 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CASP9 caspase 9 treatment ISO RGD PMID:29133031 RGD:13782296 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CAT catalase disease_progression IAGP
EXP 		associated with liver cirrhosis with Hepatitis C;DNA:SNP:promoter:-262T>C (human)
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:33010264 PMID:21907168 RGD:27095879 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CBFB core-binding factor subunit beta IEP mRNA:decreased expression:liver RGD PMID:17094378 RGD:126775147 NCBI chr16:67,029,149...67,101,058
Ensembl chr16:67,028,984...67,101,058 		JBrowse link
G CBL Cbl proto-oncogene disease_progression IEP RGD PMID:26474280 RGD:11536137 NCBI chr11:119,206,339...119,308,149
Ensembl chr11:119,206,298...119,313,926 		JBrowse link
G CBR1 carbonyl reductase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21056497 NCBI chr21:36,070,024...36,073,164
Ensembl chr21:36,069,941...36,073,166 		JBrowse link
G CBX2 chromobox 2 disease_progression IEP mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr17:79,777,311...79,787,983
Ensembl chr17:79,778,148...79,787,983 		JBrowse link
G CBX4 chromobox 4 disease_progression IDA
IEP 		protein:increased expression:cytoplasm: RGD PMID:24838576 PMID:23943028 RGD:9586738, RGD:9586739 NCBI chr17:79,833,156...79,839,440
Ensembl chr17:79,833,156...79,839,440 		JBrowse link
G CBX7 chromobox 7 IEP mRNA:decreased expression:liver RGD PMID:22041561 RGD:9587355 NCBI chr22:39,130,772...39,152,680
Ensembl chr22:39,120,167...39,152,680 		JBrowse link
G CCBE1 collagen and calcium binding EGF domains 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr18:59,430,939...59,697,721
Ensembl chr18:59,430,939...59,697,662 		JBrowse link
G CCL1 C-C motif chemokine ligand 1 ISO mRNA:increased expression:liver (mouse) RGD PMID:26569409 RGD:11344640 NCBI chr17:34,360,328...34,363,233
Ensembl chr17:34,360,328...34,363,233 		JBrowse link
G CCL13 C-C motif chemokine ligand 13 ISO mRNA:increased expression:liver (mouse) RGD PMID:26569409 RGD:11344640 NCBI chr17:34,356,480...34,358,610
Ensembl chr17:34,356,480...34,358,610 		JBrowse link
G CCL14 C-C motif chemokine ligand 14 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:35,983,288...35,986,729
Ensembl chr17:35,983,288...35,987,004 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 treatment IEP
IDA
ISO 		RNA:increased expression:liver RGD PMID:27980102 PMID:22402625 PMID:12679798 PMID:27980102 RGD:14995459, RGD:14995927, RGD:14995468, RGD:14995459 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL23 C-C motif chemokine ligand 23 ISO mRNA:increased expression:liver (mouse) RGD PMID:26569409 RGD:11344640 NCBI chr17:36,013,058...36,017,972
Ensembl chr17:36,013,056...36,017,972 		JBrowse link
G CCL3 C-C motif chemokine ligand 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16284949 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 treatment
susceptibility 		ISO
IAGP 		associated with alcoholic liver cirrhosis;DNA:SNP:promoter:-403G>A(human)
DNA:polymorphisms:promoter:-403G>A,-28C>G (human) 		RGD PMID:28011329 PMID:21610221 PMID:22374185 RGD:14995306, RGD:14995338, RGD:14995333 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCN1 cellular communication network factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17699798 NCBI chr 1:85,580,761...85,583,950
Ensembl chr 1:85,580,761...85,584,589 		JBrowse link
G CCNA1 cyclin A1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12029619 NCBI chr13:36,431,517...36,442,870
Ensembl chr13:36,431,520...36,442,870 		JBrowse link
G CCNB1 cyclin B1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245 		JBrowse link
G CCNB2 cyclin B2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:59,105,146...59,125,045
Ensembl chr15:59,105,126...59,125,045 		JBrowse link
G CCND1 cyclin D1 susceptibility IAGP
EXP
ISO 		associated with Hepatitis B, Chronic;DNA:SNP:splice-site mutation:870G>A (human)
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver (mouse) 		CTD
RGD		 PMID:12029619 PMID:19919837 PMID:22649188 PMID:25822088 PMID:26189965 More... RGD:14401586, RGD:127285675 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CCND2 cyclin D2 severity
susceptibility
disease_progression 		IEP
IAGP
IDA 		associated with hepatitis B
associated with Chronic Hepatitis C;DNA:SNP: :rs1049606(human)
DNA:hypermethylation:CpG site 		RGD PMID:33320844 PMID:22004425 PMID:31059558 PMID:33320844 RGD:151664743, RGD:151665169, RGD:151665109, RGD:151664743 NCBI chr12:4,273,762...4,305,353
Ensembl chr12:4,269,771...4,305,353 		JBrowse link
G CCNE1 cyclin E1 ameliorates ISO
EXP 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:12029619 PMID:22634754 PMID:17196522 PMID:29551768 PMID:28100771 RGD:2289277, RGD:153297807, RGD:127285675 NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312 		JBrowse link
G CCNF cyclin F EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:2,429,447...2,458,854
Ensembl chr16:2,429,394...2,458,854 		JBrowse link
G CCNG1 cyclin G1 severity
treatment
disease_progression 		ISO
IEP
IMP 		protein:decreased expression:liver (human)
protein:increased expression:liver (human)
human cells in mouse model 		RGD PMID:25431954 PMID:27982046 PMID:22835824 PMID:19584283 PMID:33543294 More... RGD:151356922, RGD:151361200, RGD:151361198, RGD:151356981, RGD:151356970, RGD:151356967, RGD:151356967, RGD:151356933, RGD:151356932 NCBI chr 5:163,437,571...163,457,640
Ensembl chr 5:163,437,569...163,448,199 		JBrowse link
G CCNG2 cyclin G2 ISO RGD PMID:27982046 RGD:151361200 NCBI chr 4:77,157,207...77,170,060
Ensembl chr 4:77,157,207...77,433,388 		JBrowse link
G CCR1 C-C motif chemokine receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16284949 NCBI chr 3:46,201,711...46,208,313
Ensembl chr 3:46,201,711...46,208,313 		JBrowse link
G CD163 CD163 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:7,470,811...7,503,777
Ensembl chr12:7,470,811...7,503,893 		JBrowse link
G CD274 CD274 molecule disease_progression EXP
IEP 		CTD Direct Evidence: marker/mechanism
associated with hepatitis B
associated with hepatitis B 		CTD
RGD		 PMID:22396772 PMID:21912640 PMID:30267213 RGD:41410800, RGD:40818240 NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566 		JBrowse link
G CD276 CD276 molecule EXP CTD Direct Evidence: therapeutic CTD PMID:16217749 NCBI chr15:73,683,944...73,714,514
Ensembl chr15:73,683,966...73,714,514 		JBrowse link
G CD34 CD34 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:207,880,972...207,911,125
Ensembl chr 1:207,880,972...207,911,402 		JBrowse link
G CD40LG CD40 ligand ISO RGD PMID:19016771 RGD:2313413 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390 		JBrowse link
G CD5L CD5 molecule like EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:157,827,068...157,841,808
Ensembl chr 1:157,830,911...157,898,256 		JBrowse link
G CD68 CD68 molecule severity IEP protein:increased expression:liver (human) RGD PMID:28656201 RGD:40924686 NCBI chr17:7,579,638...7,582,111
Ensembl chr17:7,579,491...7,582,111 		JBrowse link
G CDC20 cell division cycle 20 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:43,358,981...43,363,203
Ensembl chr 1:43,358,981...43,363,203 		JBrowse link
G CDC25C cell division cycle 25C EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:138,285,265...138,338,355
Ensembl chr 5:138,285,269...138,338,355 		JBrowse link
G CDC45 cell division cycle 45 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr22:19,479,466...19,520,612
Ensembl chr22:19,479,457...19,520,612 		JBrowse link
G CDC6 cell division cycle 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:40,287,879...40,304,657
Ensembl chr17:40,287,879...40,304,657 		JBrowse link
G CDCA2 cell division cycle associated 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:25,458,931...25,507,917
Ensembl chr 8:25,459,199...25,507,911 		JBrowse link
G CDCA3 cell division cycle associated 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:6,844,798...6,851,286
Ensembl chr12:6,844,793...6,851,292 		JBrowse link
G CDCA5 cell division cycle associated 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:65,061,093...65,084,040
Ensembl chr11:65,066,300...65,084,164 		JBrowse link
G CDCA8 cell division cycle associated 8 disease_progression IEP
EXP 		mRNA:increased expression:liver (human)
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:28284560 PMID:35693827 RGD:153344586 NCBI chr 1:37,692,516...37,709,719
Ensembl chr 1:37,692,481...37,709,719 		JBrowse link
G CDH1 cadherin 1 severity ISO
IEP
IDA 		DNA:hypermethylation
protein:decreased expression:liver
mRNA:increased expression:liver 		RGD PMID:17295234 PMID:18837082 PMID:24840851 PMID:30697077 PMID:30697077 RGD:2289638, RGD:14402047, RGD:14402046, RGD:14402045, RGD:14402045 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537 		JBrowse link
G CDH13 cadherin 13 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18425332 PMID:18553387 PMID:28284560 NCBI chr16:82,626,969...83,800,640
Ensembl chr16:82,626,965...83,800,640 		JBrowse link
G CDK1 cyclin dependent kinase 1 IEP
EXP 		protein:increased expression:liver (human)
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:28284560 PMID:19136513 RGD:2316317 NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852 		JBrowse link
G CDK12 cyclin dependent kinase 12 exacerbates IEP mRNA, protein:increased expression:liver (human) RGD PMID:31519701 RGD:151361172 NCBI chr17:39,461,486...39,567,559
Ensembl chr17:39,461,486...39,567,559 		JBrowse link
G CDK13 cyclin dependent kinase 13 onset IAGP DNA:amplification: : RGD PMID:22912832 RGD:155641228 NCBI chr 7:39,950,256...40,099,580
Ensembl chr 7:39,950,121...40,099,580 		JBrowse link
G CDK14 cyclin dependent kinase 14 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22922871 NCBI chr 7:90,596,321...91,210,590
Ensembl chr 7:90,466,424...91,210,590 		JBrowse link
G CDK4 cyclin dependent kinase 4 treatment EXP
ISO 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:26189965 PMID:33841550 RGD:152998960 NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A ISS OMIM:114550 MouseDO NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B EXP CTD Direct Evidence: marker/mechanism CTD PMID:20698225 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369 		JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C severity IEP protein:decreased expression:liver (human) RGD PMID:26606000 RGD:11354707 NCBI chr11:2,883,218...2,885,775
Ensembl chr11:2,883,213...2,885,775 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A severity IEP
EXP
IAGP
ISO 		Protein:decreased expression:liver
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hepatocellular carcinoma
DNA:hypermethylation:exon
Protein:increased expression:liver
DNA:hypermethylation:promoter 		CTD
ClinVar
RGD		 PMID:9185756 PMID:14508519 PMID:25741868 PMID:25780468 PMID:25822088 More... RGD:1600816, RGD:8552680, RGD:1600816, RGD:1600822 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301 		JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B EXP CTD Direct Evidence: marker/mechanism CTD PMID:33010264 NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305 		JBrowse link
G CDKN2C cyclin dependent kinase inhibitor 2C EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:50,960,745...50,974,634
Ensembl chr 1:50,960,745...50,974,634 		JBrowse link
G CDKN3 cyclin dependent kinase inhibitor 3 treatment
severity 		EXP
IMP
IEP 		CTD Direct Evidence: marker/mechanism
associated with alcoholism; protein:increased expression:liver
protein:decreased expression:liver
mRNA:increased expression:liver 		CTD
RGD		 PMID:28284560 PMID:23292002 PMID:23292002 PMID:27314282 PMID:22390936 RGD:15090802, RGD:15090802, RGD:15090801, RGD:15090800 NCBI chr14:54,397,007...54,420,218
Ensembl chr14:54,396,849...54,420,218 		JBrowse link
G CDT1 chromatin licensing and DNA replication factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:88,803,789...88,809,258
Ensembl chr16:88,803,789...88,809,258 		JBrowse link
G CEBPA CCAAT enhancer binding protein alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:16288022 PMID:21785164 NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534 		JBrowse link
G CEBPB CCAAT enhancer binding protein beta EXP
IEP 		CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver (human) 		CTD
RGD		 PMID:14563831 PMID:30659195 RGD:40903042 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,734...50,192,690 		JBrowse link
G CEBPD CCAAT enhancer binding protein delta EXP CTD Direct Evidence: marker/mechanism CTD PMID:14563831 NCBI chr 8:47,736,913...47,738,164
Ensembl chr 8:47,736,913...47,738,164 		JBrowse link
G CELSR3 cadherin EGF LAG seven-pass G-type receptor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:48,636,463...48,662,886
Ensembl chr 3:48,636,463...48,662,886 		JBrowse link
G CENPA centromere protein A EXP
IEP 		CTD Direct Evidence: marker/mechanism
protein:increased expression:liver (human) 		CTD
RGD		 PMID:28284560 PMID:21956590 RGD:36947377 NCBI chr 2:26,786,056...26,794,589
Ensembl chr 2:26,764,289...26,801,067 		JBrowse link
G CENPE centromere protein E EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:103,105,811...103,198,343
Ensembl chr 4:103,105,349...103,198,445 		JBrowse link
G CENPF centromere protein F EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:214,603,195...214,664,571
Ensembl chr 1:214,603,185...214,664,574 		JBrowse link
G CENPM centromere protein M EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr22:41,927,196...41,947,152
Ensembl chr22:41,927,514...41,947,152 		JBrowse link
G CENPU centromere protein U EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:184,694,085...184,734,096
Ensembl chr 4:184,694,085...184,734,130 		JBrowse link
G CENPW centromere protein W EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:126,340,115...126,483,320
Ensembl chr 6:126,340,115...126,348,875 		JBrowse link
G CEP131 centrosomal protein 131 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:81,189,596...81,222,965
Ensembl chr17:81,189,593...81,222,999 		JBrowse link
G CEP164 centrosomal protein 164 susceptibility IAGP associated with Chronic Hepatitis C;DNA:SNP: :rs573455 (human) RGD PMID:22004425 RGD:151665169 NCBI chr11:117,321,778...117,413,266
Ensembl chr11:117,314,557...117,413,266 		JBrowse link
G CEP55 centrosomal protein 55 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:93,496,612...93,529,092
Ensembl chr10:93,496,612...93,529,092 		JBrowse link
G CES1 carboxylesterase 1 disease_progression IEP protein:decreased expression:liver (human)
associated with tumor vascularization; protein:decreased expression:liver tumor (human)
mRNA, protein:decreased expression:liver tumor (human) 		RGD PMID:24259486 PMID:30901224 PMID:19658107 RGD:152995276, RGD:152995286, RGD:152995279 NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337 		JBrowse link
G CETP cholesteryl ester transfer protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:56,961,950...56,983,845
Ensembl chr16:56,961,923...56,983,845 		JBrowse link
G CFP complement factor properdin EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:47,623,282...47,630,305
Ensembl chr  X:47,623,172...47,630,305 		JBrowse link
G CHAF1B chromatin assembly factor 1 subunit B EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr21:36,385,392...36,419,015
Ensembl chr21:36,385,392...36,419,015 		JBrowse link
G CHD4 chromodomain helicase DNA binding protein 4 exacerbates HEP
IEP 		mRNA:increased expression:liver (human)
protein:increased expression:liver (human) 		RGD PMID:28486105 PMID:32070428 PMID:26095183 RGD:153323299, RGD:153323308, RGD:11571740 NCBI chr12:6,570,082...6,607,379
Ensembl chr12:6,570,082...6,614,524 		JBrowse link
G CHD5 chromodomain helicase DNA binding protein 5 IEP mRNA:decreased expression:liver RGD PMID:26517514 RGD:11537550 NCBI chr 1:6,101,787...6,180,321
Ensembl chr 1:6,101,787...6,180,321 		JBrowse link
G CKAP2L cytoskeleton associated protein 2 like EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:112,736,349...112,764,609
Ensembl chr 2:112,736,349...112,764,664 		JBrowse link
G CKAP4 cytoskeleton associated protein 4 disease_progression IEP associated with tumor vascularization; mRNA,protein:increased expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr12:106,237,881...106,248,020
Ensembl chr12:106,237,881...106,304,279 		JBrowse link
G CLDN1 claudin 1 severity IEP protein:increased expression:liver (human)
associated with liver cirrhosis;protein:increased expression:liver (human)
protein:decreased expression:liver (human) 		RGD PMID:24815833 PMID:24696415 PMID:17270214 RGD:26884345, RGD:26884352, RGD:26884348 NCBI chr 3:190,305,707...190,322,446
Ensembl chr 3:190,305,707...190,322,446 		JBrowse link
G CLEC1B C-type lectin domain family 1 member B EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:9,993,075...10,001,899
Ensembl chr12:9,985,642...10,013,424 		JBrowse link
G CLEC4G C-type lectin domain family 4 member G EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr19:7,728,957...7,732,110
Ensembl chr19:7,728,957...7,733,906 		JBrowse link
G CLEC4M C-type lectin domain family 4 member M EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr19:7,763,243...7,769,605
Ensembl chr19:7,763,210...7,769,605 		JBrowse link
G CLPTM1L CLPTM1 like susceptibility
disease_progression 		IAGP DNA:SNPs::rs401681(human)
DNA:SNP: :rs401681(human) 		RGD PMID:25339005 PMID:29042796 RGD:150530496, RGD:150537100 NCBI chr 5:1,317,752...1,345,099
Ensembl chr 5:1,317,752...1,345,099 		JBrowse link
G CLTRN collectrin, amino acid transport regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:15,627,318...15,675,644
Ensembl chr  X:15,627,318...15,675,012 		JBrowse link
G CNDP1 carnosine dipeptidase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr18:74,534,500...74,587,212
Ensembl chr18:74,534,500...74,587,212 		JBrowse link
G CNTNAP4 contactin associated protein family member 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:76,277,401...76,560,757
Ensembl chr16:76,277,278...76,560,757 		JBrowse link
G COL15A1 collagen type XV alpha 1 chain EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:98,943,907...99,070,787
Ensembl chr 9:98,943,179...99,070,787 		JBrowse link
G COL18A1 collagen type XVIII alpha 1 chain severity ISO Protein:increased expression RGD PMID:15739185 RGD:1600906 NCBI chr21:45,405,165...45,513,720
Ensembl chr21:45,405,165...45,513,720 		JBrowse link
G COLEC10 collectin subfamily member 10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:118,952,263...119,108,455
Ensembl chr 8:118,995,452...119,108,455 		JBrowse link
G COMT catechol-O-methyltransferase EXP CTD Direct Evidence: marker/mechanism CTD PMID:15341023 NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975 		JBrowse link
G COPS5 COP9 signalosome subunit 5 severity EXP
IEP 		CTD Direct Evidence: marker/mechanism
protein:increased expression:liver (human) 		CTD
RGD		 PMID:20698225 PMID:26606000 RGD:11354707 NCBI chr 8:67,043,079...67,062,133
Ensembl chr 8:67,043,079...67,083,783 		JBrowse link
G COX7B2 cytochrome c oxidase subunit 7B2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:46,734,827...46,909,245
Ensembl chr 4:46,734,827...46,909,245 		JBrowse link
G CP ceruloplasmin EXP CTD Direct Evidence: marker/mechanism CTD PMID:19229483 NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829 		JBrowse link
G CPEB3 cytoplasmic polyadenylation element binding protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:92,046,692...92,291,233
Ensembl chr10:92,046,692...92,291,078 		JBrowse link
G CPS1 carbamoyl-phosphate synthase 1 disease_progression IEP associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr 2:210,477,685...210,679,107
Ensembl chr 2:210,477,682...210,679,107 		JBrowse link
G CREBBP CREB binding protein IAGP ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: LIVER CELL CARCINOMA ClinVar PMID:26619011 NCBI chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713 		JBrowse link
G CRHBP corticotropin releasing hormone binding protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:76,953,045...76,981,159
Ensembl chr 5:76,953,045...76,981,158 		JBrowse link
G CRP C-reactive protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CSF1R colony stimulating factor 1 receptor exacerbates
severity 		HEP
IEP
IDA 		mRNA:increased expression:liver (human)
protein:increased expression:liver (human)
DNA:hypomethylation
protein:increased expression: liver (human)
DNA:hypomethylation:promoter (human) 		RGD PMID:20551429 PMID:14969845 PMID:11412385 PMID:32760707 PMID:32724427 RGD:150524279, RGD:150524302, RGD:150524301, RGD:150524286, RGD:150524282 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372 		JBrowse link
G CSF2 colony stimulating factor 2 treatment ISO RGD PMID:12731087 RGD:10450243 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170 		JBrowse link
G CSK C-terminal Src kinase IEP protein:decreased expression:liver RGD PMID:9918913 RGD:5134372 NCBI chr15:74,782,080...74,803,197
Ensembl chr15:74,782,080...74,803,197 		JBrowse link
G CSMD1 CUB and Sushi multiple domains 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:2,935,361...4,994,914
Ensembl chr 8:2,935,353...4,994,972 		JBrowse link
G CSPG4 chondroitin sulfate proteoglycan 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:75,674,322...75,713,466
Ensembl chr15:75,674,322...75,712,848 		JBrowse link
G CSRNP1 cysteine and serine rich nuclear protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:39,141,855...39,154,641
Ensembl chr 3:39,141,855...39,154,562 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 susceptibility IEP
IAGP 		protein:increased expression:CD4+ and CD8+ T cells:
DNA:SNPs: :rs231775,rs231725(human) 		RGD PMID:28648905 PMID:23432218 RGD:14398741, RGD:14398742 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965 		JBrowse link
G CTNNB1 catenin beta 1 exacerbates
severity
susceptibility 		IAGP
IEP
EXP 		DNA:mutation:exon 3
ClinVar Annotator: match by term: Hepatocellular carcinoma
ClinVar Annotator: match by term: Hepatocellular cancer
ClinVar Annotator: match by term: AXIN1-related condition | ClinVar Annotator: match by term: Hepatocellular cancer | ClinVar Annotator: match by term: Hepatocellular carcinoma
DNA:missense mutations:exon 3:multiple (human)
DNA:Mutations:exon:
protein:increased expression:liver:
associated with hepatitis B;DNA:SNPs: :rs3864004,rs11564475(human)
associated with Hepatitis B, Chronic,DNA:SNP, haplotype: :rs3864004 (human)
CTD Direct Evidence: marker/mechanism 		ClinVar
CTD
OMIM
RGD		 PMID:10192393 PMID:10435629 PMID:20118494 PMID:21147764 PMID:21903672 More... RGD:734850, RGD:150429592, RGD:14402052, RGD:14402052, RGD:14402040, RGD:14402039 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096 		JBrowse link
G CTSB cathepsin B ISO RGD PMID:15641152 RGD:2315605 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533 		JBrowse link
G CTSD cathepsin D EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573 		JBrowse link
G CTSL cathepsin L ISO RGD PMID:15641152 RGD:2315605 NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,724,051...87,731,469 		JBrowse link
G CUX1 cut like homeobox 1 IEP mRNA:increased expression:liver (human) RGD PMID:30561038 RGD:152985541 NCBI chr 7:101,816,007...102,283,958
Ensembl chr 7:101,815,904...102,283,958 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 disease_progression
treatment 		IEP
ISO 		RGD PMID:28592115 PMID:27245433 PMID:28638480 RGD:27095889, RGD:27095899, RGD:27095898 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCL11 C-X-C motif chemokine ligand 11 ISO mRNA:increased expression:liver (mouse) RGD PMID:26569409 RGD:11344640 NCBI chr 4:76,033,682...76,036,070
Ensembl chr 4:76,033,682...76,041,415 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19363144 PMID:28284560 NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493 		JBrowse link
G CXCL14 C-X-C motif chemokine ligand 14 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:135,570,679...135,578,991
Ensembl chr 5:135,570,679...135,579,279 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 disease_progression
susceptibility 		IEP
EXP
IAGP 		protein:increased expression:liver (human)
CTD Direct Evidence: marker/mechanism|therapeutic
DNA:SNPs, haplotype:multiple
mRNA:increased expression:liver (human) 		CTD
RGD		 PMID:12432545 PMID:35776891 PMID:26078356 PMID:24381110 PMID:30523154 RGD:11526468, RGD:26884366, RGD:26884364 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 treatment
severity 		IEP
HEP 		human cells in mouse model
protein:increased expression:liver (human) 		RGD PMID:33574707 PMID:30034941 RGD:151665327, RGD:151665331 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177 		JBrowse link
G CYLD CYLD lysine 63 deubiquitinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:21109933 NCBI chr16:50,742,086...50,801,935
Ensembl chr16:50,742,050...50,801,935 		JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15341023 NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15341023 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 ameliorates HDA DNA:hypermethylation:promoter: (human) RGD PMID:20345479 RGD:151665497 NCBI chr20:54,143,538...54,173,986
Ensembl chr20:54,153,446...54,173,986 		JBrowse link
G CYP26B1 cytochrome P450 family 26 subfamily B member 1 disease_progression IEP mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr 2:72,129,238...72,147,862
Ensembl chr 2:72,129,238...72,147,862 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398 		JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 susceptibility IAGP associated with hepatitis C; DNA:polymorphisms: : RGD PMID:11021356 RGD:124713413 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 EXP
IAGP 		CTD Direct Evidence: marker/mechanism
DNA, mRNA:SNP, Decreased expression:liver: rs2031920 (human)
associated with alcohol dependence 		CTD
RGD		 PMID:15162526 PMID:29765251 PMID:20364586 RGD:14700899, RGD:14700882 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G CYP39A1 cytochrome P450 family 39 subfamily A member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:46,549,580...46,652,818
Ensembl chr 6:46,549,580...46,652,830 		JBrowse link
G CYP4A11 cytochrome P450 family 4 subfamily A member 11 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:46,929,188...46,941,476
Ensembl chr 1:46,929,177...46,941,484 		JBrowse link
G DAB2IP DAB2 interacting protein severity IEP mRNA:decreased expression:liver (human)
protein:decreased expression:liver (human) 		RGD PMID:31176165 PMID:22168621 RGD:151665110, RGD:151665148 NCBI chr 9:121,567,074...121,785,530
Ensembl chr 9:121,567,057...121,785,530 		JBrowse link
G DBH dopamine beta-hydroxylase EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:133,636,363...133,659,329
Ensembl chr 9:133,636,363...133,659,329 		JBrowse link
G DCAF4L2 DDB1 and CUL4 associated factor 4 like 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:87,870,747...87,874,015
Ensembl chr 8:87,870,747...87,874,015 		JBrowse link
G DCN decorin EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:91,140,484...91,182,817
Ensembl chr12:91,140,484...91,183,217 		JBrowse link
G DDR1 discoidin domain receptor tyrosine kinase 1 severity ISO
IEP 		mRNA:increased expression:liver (human) RGD PMID:33173221 PMID:33173221 RGD:151347691, RGD:151347691 NCBI chr 6:30,880,970...30,900,156
Ensembl chr 6:30,876,421...30,900,156 		JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 treatment
disease_progression 		IEP RGD PMID:33969575 PMID:26362312 RGD:150429748, RGD:11086753 NCBI chr 1:162,630,863...162,787,405
Ensembl chr 1:162,631,373...162,787,405 		JBrowse link
G DDX3X DEAD-box helicase 3 X-linked exacerbates
sexual_dimorphism 		ISO
IEP 		associated with hepatitis B; mRNA,protein:decreased expression:liver (human) RGD PMID:30297359 PMID:16301996 RGD:151356499, RGD:151356660 NCBI chr  X:41,333,308...41,364,472
Ensembl chr  X:41,333,348...41,364,472 		JBrowse link
G DEPDC1 DEP domain containing 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:68,474,152...68,497,082
Ensembl chr 1:68,474,152...68,497,221 		JBrowse link
G DEPDC1B DEP domain containing 1B EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:60,596,912...60,700,166
Ensembl chr 5:60,596,912...60,700,190 		JBrowse link
G DEPDC5 DEP domain containing 5, GATOR1 subcomplex subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:21725309 NCBI chr22:31,753,968...31,908,033
Ensembl chr22:31,753,867...31,908,033 		JBrowse link
G DICER1 dicer 1, ribonuclease III susceptibility IAGP associated with hepatitis B; DNA:SNP: :rs1057035 T>C (human) RGD PMID:23868705 RGD:149735346 NCBI chr14:95,086,228...95,158,010
Ensembl chr14:95,086,228...95,158,010 		JBrowse link
G DIPK2B divergent protein kinase domain 2B EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:45,148,373...45,200,876
Ensembl chr  X:45,148,373...45,200,901 		JBrowse link
G DIRAS3 DIRAS family GTPase 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:68,045,962...68,050,627
Ensembl chr 1:68,045,886...68,051,717 		JBrowse link
G DLGAP1-AS2 DLGAP1 antisense RNA 2 severity IEP mRNA:increased expression:liver (human) RGD PMID:33195697 RGD:152995478 NCBI chr18:3,603,737...3,610,089
Ensembl chr18:3,594,114...3,610,103 		JBrowse link
G DLGAP5 DLG associated protein 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:55,148,135...55,191,585
Ensembl chr14:55,148,112...55,191,608 		JBrowse link
G DLK1 delta like non-canonical Notch ligand 1 ISO mRNA:increased expression:liver (mouse) RGD PMID:26569409 RGD:11344640 NCBI chr14:100,726,892...100,738,224
Ensembl chr14:100,725,705...100,738,224 		JBrowse link
G DMGDH dimethylglycine dehydrogenase disease_progression IEP associated with tumor vascularization; mRNA,protein:decreased expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr 5:78,997,564...79,069,674
Ensembl chr 5:78,997,564...79,236,038 		JBrowse link
G DNAJC6 DnaJ heat shock protein family (Hsp40) member C6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:65,264,749...65,415,871
Ensembl chr 1:65,248,219...65,415,871 		JBrowse link
G DNASE1L3 deoxyribonuclease 1L3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:58,192,257...58,210,972
Ensembl chr 3:58,192,257...58,214,697 		JBrowse link
G DNMT1 DNA methyltransferase 1 ISO mRNA, protein:increased expression:liver RGD PMID:11844796 RGD:2289670 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha IEP
ISO 		protein:increased expression:liver:
mRNA, protein:increased expression:liver 		RGD PMID:15885882 PMID:11844796 RGD:9588598, RGD:2289670 NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta IEP
ISO 		mRNA:increased expression:liver:
mRNA, protein:increased expression:liver 		RGD PMID:15885882 PMID:11844796 RGD:9588598, RGD:2289670 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359 		JBrowse link
G DPYD dihydropyrimidine dehydrogenase EXP CTD Direct Evidence: marker/mechanism CTD PMID:18019677 NCBI chr 1:97,077,743...97,921,059
Ensembl chr 1:97,077,743...97,995,000 		JBrowse link
G DSN1 DSN1 component of MIS12 kinetochore complex disease_progression IEP RGD PMID:30136646 RGD:27372884 NCBI chr20:36,751,795...36,773,763
Ensembl chr20:36,751,791...36,773,818 		JBrowse link
G DTL denticleless E3 ubiquitin protein ligase homolog EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:212,035,748...212,105,013
Ensembl chr 1:212,035,553...212,107,400 		JBrowse link
G DUXAP9 double homeobox A pseudogene 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34086387 NCBI chr14:19,062,377...19,107,497
Ensembl chr14:19,104,100...19,104,713
Ensembl chr14:19,104,100...19,104,713 		JBrowse link
G DYNLRB1 dynein light chain roadblock-type 1 IEP RGD PMID:11750132 RGD:13208527 NCBI chr20:34,515,602...34,540,958
Ensembl chr20:34,516,395...34,540,958 		JBrowse link
G DYNLRB2 dynein light chain roadblock-type 2 IEP RGD PMID:11750132 RGD:13208527 NCBI chr16:80,540,734...80,550,811
Ensembl chr16:80,540,734...80,550,811 		JBrowse link
G E2F1 E2F transcription factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12029619 PMID:15565109 PMID:28284560 NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385 		JBrowse link
G E2F8 E2F transcription factor 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:19,224,063...19,241,655
Ensembl chr11:19,224,063...19,241,620 		JBrowse link
G EAF2 ELL associated factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20564326 NCBI chr 3:121,835,209...121,886,526
Ensembl chr 3:121,835,183...121,886,526 		JBrowse link
G ECM1 extracellular matrix protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:150,508,109...150,513,789
Ensembl chr 1:150,508,062...150,513,789 		JBrowse link
G ECT2 epithelial cell transforming 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:172,750,726...172,829,265
Ensembl chr 3:172,750,682...172,821,474 		JBrowse link
G EEF2 eukaryotic translation elongation factor 2 exacerbates HEP protein:increased expression, increased phosphorylation:liver (human) RGD PMID:28060762 RGD:153298915 NCBI chr19:3,976,056...3,985,463
Ensembl chr19:3,976,056...3,985,463 		JBrowse link
G EFEMP1 EGF containing fibulin extracellular matrix protein 1 disease_progression IEP protein:decreased expression:liver: RGD PMID:23936443 RGD:10401793 NCBI chr 2:55,865,967...55,923,782
Ensembl chr 2:55,865,967...55,924,139 		JBrowse link
G EFTUD2 elongation factor Tu GTP binding domain containing 2 severity
ameliorates 		IEP
IMP 		RGD PMID:34282556 PMID:34282556 RGD:155791664, RGD:155791664 NCBI chr17:44,849,948...44,899,445
Ensembl chr17:44,849,948...44,899,445 		JBrowse link
G EGF epidermal growth factor susceptibility EXP
IAGP 		CTD Direct Evidence: marker/mechanism
associated with hepatitis B;DNA:SNP:exon: (rs11569017) (human)
associated with liver cirrhosis;DNA:SNP:5'UTR: (rs4444903) (human) 		CTD
RGD		 PMID:9029167 PMID:23790025 PMID:18167406 RGD:14695014, RGD:14695013 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G EGFR epidermal growth factor receptor disease_progression EXP
IEP 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:9029167 PMID:11355950 RGD:126781769 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EGR1 early growth response 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303 		JBrowse link
G EGR2 early growth response 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:62,811,996...62,819,167
Ensembl chr10:62,811,996...62,819,167 		JBrowse link
G EHD3 EH domain containing 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:31,234,152...31,269,451
Ensembl chr 2:31,234,152...31,269,451 		JBrowse link
G EIF3H eukaryotic translation initiation factor 3 subunit H EXP CTD Direct Evidence: marker/mechanism CTD PMID:14578863 NCBI chr 8:116,642,130...116,766,374
Ensembl chr 8:116,642,130...116,766,925 		JBrowse link
G ENAH ENAH actin regulator disease_progression IEP mRNA:increased expression:liver (human) RGD PMID:35030977 RGD:155791678 NCBI chr 1:225,486,829...225,653,878
Ensembl chr 1:225,486,765...225,653,142 		JBrowse link
G ENG endoglin ISO protein:increased expression:liver (rat) RGD PMID:20368095 RGD:7257538 NCBI chr 9:127,815,016...127,854,658
Ensembl chr 9:127,811,130...127,854,773 		JBrowse link
G ENO1 enolase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190 		JBrowse link
G EP300 E1A binding protein p300 ISO protein:increased expression:liver (rat) RGD PMID:17083329 RGD:2312274 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,510...41,180,077 		JBrowse link
G EPAS1 endothelial PAS domain protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26735578 NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697 		JBrowse link
G EPCAM epithelial cell adhesion molecule severity IEP protein:increased expression:liver RGD PMID:24616575 RGD:14695007 NCBI chr 2:47,369,311...47,387,020
Ensembl chr 2:47,345,158...47,387,601 		JBrowse link
G EPHB1 EPH receptor B1 ISO protein:increased phosphorylation:liver (mouse) RGD PMID:28100771 RGD:127285675 NCBI chr 3:134,795,260...135,260,467
Ensembl chr 3:134,795,260...135,260,467 		JBrowse link
G EPHX1 epoxide hydrolase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:7892276 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563 		JBrowse link
G EPO erythropoietin disease_progression IEP mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700 		JBrowse link
G EPS8L3 EPS8 signaling adaptor L3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:109,750,080...109,763,923
Ensembl chr 1:109,750,080...109,764,027 		JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 disease_progression IEP RGD PMID:11355950 RGD:126781769 NCBI chr12:56,080,108...56,103,505
Ensembl chr12:56,076,799...56,103,505 		JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 IAGP DNA:insertion/deletion:3'UTR:rs6147150 (human) RGD PMID:22294845 RGD:126781763 NCBI chr 2:211,375,717...212,538,802
Ensembl chr 2:211,375,717...212,538,841 		JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit IEP mRNA, protein:increased expression:liver (human) RGD PMID:15922480 RGD:155598683 NCBI chr19:45,407,334...45,451,547
Ensembl chr19:45,407,334...45,478,828 		JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit susceptibility
disease_progression 		IAGP DNA:SNPs:exon 23: p.K751Q (human)
DNA:SNP:cd: 312A>G (human)
DNA:SNPs:exon 23: p.K751Q (rs13181) (human)
DNA:SNPs:exon 23: p.K751Q (human) 		RGD PMID:19919686 PMID:28927037 PMID:28598207 PMID:25531380 RGD:25671459, RGD:150530503, RGD:25671461, RGD:25671460 NCBI chr19:45,349,837...45,370,573
Ensembl chr19:45,349,837...45,370,918 		JBrowse link
G EREG epiregulin EXP CTD Direct Evidence: marker/mechanism CTD PMID:35776891 NCBI chr 4:74,365,145...74,388,749
Ensembl chr 4:74,365,145...74,388,749 		JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 IDA DNA:hypomethylation: CpG islands: RGD PMID:20165882 RGD:14694974 NCBI chr17:64,039,142...64,130,144
Ensembl chr17:64,039,080...64,130,819 		JBrowse link
G ERP29 endoplasmic reticulum protein 29 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr12:112,013,426...112,023,449
Ensembl chr12:112,013,348...112,023,449 		JBrowse link
G ESM1 endothelial cell specific molecule 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:54,977,867...54,985,593
Ensembl chr 5:54,977,867...55,022,671 		JBrowse link
G ESR1 estrogen receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19363144 PMID:28284560 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G ETFA electron transfer flavoprotein subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr15:76,215,353...76,311,469
Ensembl chr15:76,188,555...76,311,730 		JBrowse link
G EXO1 exonuclease 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:241,847,986...241,889,939
Ensembl chr 1:241,847,967...241,895,148 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit susceptibility IEP
EXP
IAGP 		mRNA:increased expression:liver (human)
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :multiple 		CTD
RGD		 PMID:28284560 PMID:34545456 PMID:24211739 PMID:25226601 PMID:24040354 More... RGD:10755339, RGD:126779608, RGD:126779595, RGD:11537550 NCBI chr 7:148,807,383...148,884,291
Ensembl chr 7:148,807,257...148,884,321 		JBrowse link
G F2 coagulation factor II, thrombin severity EXP
IEP 		CTD Direct Evidence: marker/mechanism
associated with liver cirrhosis;protein:altered expression, altered processing:liver (human) 		CTD
RGD		 PMID:2821104 PMID:7620113 RGD:14975114 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506 		JBrowse link
G FABP5 fatty acid binding protein 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 8:81,280,536...81,284,775
Ensembl chr 8:81,280,536...81,284,777 		JBrowse link
G FAM111B FAM111 trypsin like peptidase B EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:59,107,237...59,127,412
Ensembl chr11:59,107,185...59,127,412 		JBrowse link
G FAM180A family with sequence similarity 180 member A EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:135,729,592...135,748,813
Ensembl chr 7:135,728,348...135,748,813 		JBrowse link
G FAM72B family with sequence similarity 72 member B EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:121,167,646...121,184,340
Ensembl chr 1:121,167,646...121,185,539 		JBrowse link
G FAM83D family with sequence similarity 83 member D EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:38,926,417...38,953,106
Ensembl chr20:38,926,312...38,953,106 		JBrowse link
G FANCD2 FA complementation group D2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:10,026,437...10,101,932
Ensembl chr 3:10,026,370...10,101,932 		JBrowse link
G FANCI FA complementation group I EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:89,243,979...89,317,259
Ensembl chr15:89,243,945...89,317,261 		JBrowse link
G FAS Fas cell surface death receptor treatment ISO
IEP 		protein:increased expression:liver: RGD PMID:29634416 PMID:30737368 PMID:11274632 RGD:13792608, RGD:14700700, RGD:14700677 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FASLG Fas ligand IEP protein:increased expression:liver: RGD PMID:11274632 RGD:14700677 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G FASN fatty acid synthase EXP CTD Direct Evidence: marker/mechanism CTD PMID:14563831 PMID:15543204 PMID:21147110 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294 		JBrowse link
G FAT1 FAT atypical cadherin 1 disease_progression HEP mRNA,protein:increased expression:liver (human) RGD PMID:24590895 RGD:151347630 NCBI chr 4:186,587,794...186,726,696
Ensembl chr 4:186,587,794...186,726,722 		JBrowse link
G FATE1 fetal and adult testis expressed 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15580283 NCBI chr  X:151,716,035...151,723,194
Ensembl chr  X:151,716,035...151,723,194 		JBrowse link
G FBP1 fructose-bisphosphatase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22039417 NCBI chr 9:94,603,133...94,640,263
Ensembl chr 9:94,603,133...94,640,249 		JBrowse link
G FBXL18 F-box and leucine rich repeat protein 18 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:5,454,425...5,513,809
Ensembl chr 7:5,431,335...5,513,809 		JBrowse link
G FBXO11 F-box protein 11 exacerbates
ameliorates 		IEP
HEP 		mRNA:increased expression:liver (human)
protein:increased expression:liver (human) 		RGD PMID:29518611 PMID:29603830 PMID:32657545 RGD:152025259, RGD:152025266, RGD:152025263 NCBI chr 2:47,806,920...47,906,498
Ensembl chr 2:47,789,316...47,906,498 		JBrowse link
G FCN2 ficolin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:134,864,144...134,887,523
Ensembl chr 9:134,880,810...134,887,523 		JBrowse link
G FCN3 ficolin 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:27,369,110...27,374,824
Ensembl chr 1:27,369,110...27,374,824 		JBrowse link
G FDFT1 farnesyl-diphosphate farnesyltransferase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr 8:11,795,582...11,839,298
Ensembl chr 8:11,795,573...11,839,395 		JBrowse link
G FES FES proto-oncogene, tyrosine kinase exacerbates IDA DNA:hypermethylation:promoter (human) RGD PMID:31038805 RGD:153323297 NCBI chr15:90,884,504...90,895,776
Ensembl chr15:90,883,695...90,895,776 		JBrowse link
G FGF19 fibroblast growth factor 19 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25822088 NCBI chr11:69,698,238...69,704,022
Ensembl chr11:69,698,238...69,704,022 		JBrowse link
G FGF3 fibroblast growth factor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25822088 NCBI chr11:69,809,968...69,819,416
Ensembl chr11:69,809,968...69,819,416 		JBrowse link
G FGF4 fibroblast growth factor 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25822088 NCBI chr11:69,771,022...69,775,341
Ensembl chr11:69,771,022...69,775,341 		JBrowse link
G FGFR1 fibroblast growth factor receptor 1 treatment IDA
EXP
IMP 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:36029209 PMID:16452204 PMID:20155451 PMID:21573021 RGD:25330358, RGD:25440478, RGD:25440476 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 severity IAGP associated with hepatitis B;DNA:SNPs: promoter, intron:rs308379, rs1219648 (human) RGD PMID:30952770 RGD:38501096 NCBI chr10:121,478,330...121,598,458
Ensembl chr10:121,478,332...121,598,458 		JBrowse link
G FGFR4 fibroblast growth factor receptor 4 treatment IEP RGD PMID:32677805 RGD:150520166 NCBI chr 5:177,086,915...177,098,144
Ensembl chr 5:177,086,905...177,098,144 		JBrowse link
G FH fumarate hydratase IAGP ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar PMID:10896297 PMID:15221078 PMID:16876016 PMID:17182618 PMID:18313410 More... NCBI chr 1:241,497,603...241,519,755
Ensembl chr 1:241,497,511...241,519,799 		JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase ISO RGD PMID:12112319 RGD:632723 NCBI chr 3:59,747,277...61,251,452
Ensembl chr 3:59,747,277...61,251,459 		JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 ameliorates IMP human cells in mouse model RGD PMID:27511526 RGD:149735514 NCBI chr13:28,003,274...28,100,576
Ensembl chr13:28,003,274...28,100,592 		JBrowse link
G FLVCR1 FLVCR choline and heme transporter 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:212,858,275...212,899,363
Ensembl chr 1:212,858,275...212,899,363 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:9029167 PMID:28284560 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190 		JBrowse link
G FOSB FosB proto-oncogene, AP-1 transcription factor subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr19:45,467,996...45,475,179
Ensembl chr19:45,467,995...45,475,179 		JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit IEP mRNA:increased expression:liver (human) RGD PMID:30086463 PMID:32048611 RGD:153344517, RGD:153344521 NCBI chr 2:28,392,858...28,417,317
Ensembl chr 2:28,392,448...28,417,317 		JBrowse link
G FOXA1 forkhead box A1 susceptibility
sexual_dimorphism
disease_progression 		IAGP
HEP
IEP 		DNA:VNTR, SNPs, haplotypes:multiple:
protein:decreased expression:liver 		RGD PMID:31400761 PMID:29208003 PMID:25965836 RGD:151665752, RGD:151665820, RGD:11054501 NCBI chr14:37,589,552...37,595,249
Ensembl chr14:37,589,552...37,596,059 		JBrowse link
G FOXM1 forkhead box M1 EXP
ISS 		CTD Direct Evidence: marker/mechanism
OMIM:114550 		CTD
MouseDO		 PMID:15082532 PMID:17173139 PMID:28284560 NCBI chr12:2,857,680...2,877,174
Ensembl chr12:2,857,680...2,877,174 		JBrowse link
G FOXO1 forkhead box O1 IEP mRNA:decreased expression:liver RGD PMID:28972178 RGD:14401599 NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641 		JBrowse link
G FOXP1 forkhead box P1 treatment ISO RGD PMID:25156538 RGD:9587823 NCBI chr 3:70,954,708...71,583,978
Ensembl chr 3:70,954,693...71,583,978 		JBrowse link
G FOXP3 forkhead box P3 IEP protein:increased expression:liver RGD PMID:21086571 RGD:38548919 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G FOXP4-AS1 FOXP4 antisense RNA 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34545456 NCBI chr 6:41,523,895...41,548,621
Ensembl chr 6:41,436,972...41,562,194 		JBrowse link
G FST follistatin EXP CTD Direct Evidence: marker/mechanism CTD PMID:12203361 PMID:19363144 NCBI chr 5:53,480,629...53,487,134
Ensembl chr 5:53,480,626...53,487,134 		JBrowse link
G FTH1 ferritin heavy chain 1 ISO mRNA:increased expression:liver (rat) RGD PMID:9054589 RGD:632698 NCBI chr11:61,964,285...61,967,634
Ensembl chr11:61,959,718...61,967,634 		JBrowse link
G FUBP1 far upstream element binding protein 1 exacerbates
ameliorates 		IEP
IMP 		mRNA:increased expression:liver (human)
associated with Chronic Hepatitis C;mRNA:increased expression:liver (human)
human cell line in a mouse model 		RGD PMID:31587040 PMID:25995247 PMID:19637194 RGD:151361188, RGD:151361196, RGD:151361194 NCBI chr 1:77,944,055...77,979,501
Ensembl chr 1:77,944,055...77,979,110 		JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 treatment IMP associated with Glycogen Storage Disease IA, human gene in a mouse model RGD PMID:28096054 RGD:14695537 NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase disease_progression ISO
IEP 		mRNA:increased expression:liver (human) RGD PMID:25473368 PMID:35693827 RGD:10449118, RGD:153344586 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572 		JBrowse link
G GABRD gamma-aminobutyric acid type A receptor subunit delta EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:2,019,345...2,030,758
Ensembl chr 1:2,019,329...2,030,758 		JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase EXP CTD Direct Evidence: marker/mechanism CTD PMID:16767786 PMID:21472284 NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374 		JBrowse link
G GBA3 glucosylceramidase beta 3 (gene/pseudogene) EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:22,692,937...22,819,569
Ensembl chr 4:22,692,914...22,819,575 		JBrowse link
G GC GC vitamin D binding protein susceptibility ISO
IAGP 		protein:increased expression:liver
associated with Hepatitis B, Chronic;DNA:SNP: :rs7041(human) 		RGD PMID:21683810 PMID:25541958 RGD:5509919, RGD:14402025 NCBI chr 4:71,741,693...71,805,520
Ensembl chr 4:71,741,696...71,804,041 		JBrowse link
G GDF15 growth differentiation factor 15 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20512989 NCBI chr19:18,386,158...18,389,176
Ensembl chr19:18,374,731...18,389,176 		JBrowse link
G GDF2 growth differentiation factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23936038 PMID:28284560 NCBI chr10:47,322,454...47,327,588
Ensembl chr10:47,322,454...47,327,588 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 disease_progression IEP RNA,protein:increased expression, activity:liver:
HBV associated 		RGD PMID:11940314 PMID:10572675 PMID:27793641 RGD:14701040, RGD:14701048, RGD:14701041 NCBI chr22:24,583,750...24,628,996
Ensembl chr22:24,594,811...24,629,005 		JBrowse link
G GHR growth hormone receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:42,423,439...42,721,878
Ensembl chr 5:42,423,439...42,721,878 		JBrowse link
G GINS1 GINS complex subunit 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:25,407,673...25,448,563
Ensembl chr20:25,391,008...25,452,700 		JBrowse link
G GJB1 gap junction protein beta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17978847 NCBI chr  X:71,215,239...71,225,516
Ensembl chr  X:71,212,811...71,225,516 		JBrowse link
G GJB2 gap junction protein beta 2 ISO DNA, mRNA:promoter hypermethylation, decreased expression:liver RGD PMID:17295234 RGD:2289638 NCBI chr13:20,187,470...20,192,938
Ensembl chr13:20,187,463...20,192,938 		JBrowse link
G GLI1 GLI family zinc finger 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26189965 NCBI chr12:57,459,785...57,472,268
Ensembl chr12:57,459,785...57,472,268 		JBrowse link
G GLUL glutamate-ammonia ligase EXP CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr 1:182,378,098...182,391,790
Ensembl chr 1:182,378,098...182,392,206 		JBrowse link
G GMNN geminin DNA replication inhibitor EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:24,774,937...24,786,099
Ensembl chr 6:24,774,931...24,786,099 		JBrowse link
G GMPS guanine monophosphate synthase ISO protein:increased activity:hepatoma (rat) RGD PMID:6861338 RGD:5135537 NCBI chr 3:155,869,430...155,944,020
Ensembl chr 3:155,870,650...155,944,020 		JBrowse link
G GNAO1 G protein subunit alpha o1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:56,191,489...56,357,444
Ensembl chr16:56,189,660...56,357,444 		JBrowse link
G GNAZ G protein subunit alpha z EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr22:23,070,519...23,125,032
Ensembl chr22:23,070,519...23,125,032 		JBrowse link
G GNMT glycine N-methyltransferase EXP
ISS 		CTD Direct Evidence: marker/mechanism
OMIM:114550 		CTD
MouseDO		 PMID:19146867 PMID:31086990 NCBI chr 6:42,960,754...42,963,880
Ensembl chr 6:42,960,754...42,963,880 		JBrowse link
G GOLM1 golgi membrane protein 1 severity IEP protein:increased expression:serum
mRNA, protein:increased expression:liver 		RGD PMID:21140449 PMID:21443671 RGD:401827118, RGD:401827119 NCBI chr 9:86,026,146...86,100,149
Ensembl chr 9:86,026,146...86,100,173 		JBrowse link
G GPC1 glypican 1 disease_progression IEP mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr 2:240,435,663...240,468,076
Ensembl chr 2:240,435,663...240,468,076 		JBrowse link
G GPC3 glypican 3 disease_progression
exacerbates
severity
treatment 		EXP
IEP
HEP
ISO 		CTD Direct Evidence: marker/mechanism
protein:increased expression:liver (human)
protein:increased expression:blood serum (human)
mRNA,protein:increased expression:peripheral blood mononuclear cell,blood serum, liver (human)
mRNA:increased expression:Peripheral Blood (human)
protein:increased expression:serum 		CTD
RGD		 PMID:16698587 PMID:28284560 PMID:22883669 PMID:28801286 PMID:27286460 More... RGD:243065139, RGD:243065135, RGD:243065134, RGD:243065131, RGD:243065125, RGD:14695020, RGD:14695020, RGD:14695019 NCBI chr  X:133,535,745...133,985,594
Ensembl chr  X:133,535,745...133,987,100 		JBrowse link
G GPM6A glycoprotein M6A EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:175,632,937...176,002,393
Ensembl chr 4:175,632,934...176,002,664 		JBrowse link
G GPR158 G protein-coupled receptor 158 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:25,175,001...25,602,229
Ensembl chr10:25,174,802...25,602,229 		JBrowse link
G GPR182 G protein-coupled receptor 182 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:56,994,492...56,998,877
Ensembl chr12:56,994,492...56,998,447 		JBrowse link
G GPX1 glutathione peroxidase 1 severity
no_association
susceptibility 		IAGP
IGI 		associated with hepatitis C;DNA:missense mutation:CDS:p.P198L (rs1050450) (human)
DNA:missense mutation:CDS:p.P198L (human)
associated with alcoholic liver cirrhosis;DNA:missense mutation:CDS:p.P198L (human) 		RGD PMID:26990426 PMID:25894370 PMID:19929244 PMID:16510607 RGD:11533013, RGD:152998906, RGD:152995483, RGD:151708729 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GPX3 glutathione peroxidase 3 severity
disease_progression 		IEP
IDA 		mRNA,protein:decreased expression:liver, blood plasma (human)
DNA:hypermethylation 		RGD PMID:25333265 PMID:27570561 PMID:25445749 RGD:151665355, RGD:401827855, RGD:151665509 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988 		JBrowse link
G GRB7 growth factor receptor bound protein 7 exacerbates IEP protein:increased expression:liver (human) RGD PMID:17634422 RGD:151347655 NCBI chr17:39,737,938...39,747,285
Ensembl chr17:39,737,927...39,747,291 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 susceptibility
no_association 		IAGP
EXP 		DNA:deletion:cds (human)
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:7892276 PMID:11859714 PMID:20672314 PMID:20683151 RGD:7488953, RGD:14700979, RGD:14700951 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 EXP
IEP 		CTD Direct Evidence: marker/mechanism
DNA:increased methylation:promoter 		CTD
RGD		 PMID:9029167 PMID:22536438 RGD:14401712 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G GSTT1 glutathione S-transferase theta 1 susceptibility
no_association 		IAGP DNA:deletion RGD PMID:23053942 PMID:20672314 PMID:20683151 RGD:14401714, RGD:14700979, RGD:14700951
G GTSE1 G2 and S-phase expressed 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr22:46,296,870...46,330,810
Ensembl chr22:46,296,870...46,330,810 		JBrowse link
G GYS2 glycogen synthase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:21,532,577...21,604,847
Ensembl chr12:21,536,107...21,604,847 		JBrowse link
G H19 H19 imprinted maternally expressed transcript ISO mRNA:increased expression:liver RGD PMID:17393425 RGD:2306187 NCBI chr11:1,995,176...2,001,266
Ensembl chr11:1,995,165...2,004,552 		JBrowse link
G HAMP hepcidin antimicrobial peptide EXP
IDA
IEP 		CTD Direct Evidence: marker/mechanism
DNA:hypermethylation,hypomethylation:promoter
mRNA:decreased expression:liver (human) 		CTD
RGD		 PMID:28284560 PMID:29235098 PMID:29235098 RGD:15042879, RGD:15042879 NCBI chr19:35,282,528...35,285,143
Ensembl chr19:35,280,716...35,285,143 		JBrowse link
G HAO2 hydroxyacid oxidase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:119,368,785...119,394,130
Ensembl chr 1:119,368,779...119,394,130 		JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 disease_progression IEP mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr 5:157,029,413...157,069,407
Ensembl chr 5:157,026,742...157,069,396 		JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 disease_progression IAGP associated with hepatitis B;DNA:SNP: : ���1516 G>T (human) RGD PMID:27034168 RGD:40818257 NCBI chr 5:157,085,832...157,109,044
Ensembl chr 5:157,085,422...157,142,869 		JBrowse link
G HDAC2 histone deacetylase 2 disease_progression IEP mRNA:increased expression:liver: RGD PMID:24448241 RGD:9590206 NCBI chr 6:113,933,028...113,971,148
Ensembl chr 6:113,933,028...114,011,308 		JBrowse link
G HDAC4 histone deacetylase 4 IEP mRNA:increased expression:liver: RGD PMID:21837748 RGD:9681451 NCBI chr 2:239,048,168...239,401,649
NCBI chr 2:239,193,331...239,195,457
Ensembl chr 2:239,048,168...239,401,654 		JBrowse link
G HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28919514 NCBI chr 4:88,457,119...88,506,163
Ensembl chr 4:88,457,119...88,506,163 		JBrowse link
G HFE homeostatic iron regulator disease_progression IAGP
IEP 		associated with Liver Cirrhosis;DNA:missense mutation:cds:p.C282Y (human) RGD PMID:20019189 PMID:29642405 RGD:2317357, RGD:14746967 NCBI chr 6:26,087,429...26,098,343
Ensembl chr 6:26,087,226...26,098,343 		JBrowse link
G HGF hepatocyte growth factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:9932610 PMID:11896611 NCBI chr 7:81,699,010...81,770,047
Ensembl chr 7:81,699,010...81,770,438 		JBrowse link
G HGFAC HGF activator EXP CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr 4:3,441,005...3,449,486
Ensembl chr 4:3,441,968...3,449,486 		JBrowse link
G HHIP hedgehog interacting protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:18559595 NCBI chr 4:144,646,156...144,745,271
Ensembl chr 4:144,646,156...144,745,271 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha treatment
disease_progression 		ISO
IEP 		protein:increased expression:liver (human) RGD PMID:19335982 PMID:31321740 PMID:26078356 RGD:9068886, RGD:155882550, RGD:11526468 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HILPDA hypoxia inducible lipid droplet associated disease_progression IEP
IMP 		mRNA, protein:increased expression:liver (human)
mRNA:increased expression:liver (human)
human cells in mouse model 		RGD PMID:31142329 PMID:35693827 PMID:30205391 PMID:31142329 RGD:153344574, RGD:153344586, RGD:153344577, RGD:153344574 NCBI chr 7:128,455,878...128,458,418
Ensembl chr 7:128,455,849...128,458,418 		JBrowse link
G HJURP Holliday junction recognition protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:233,836,702...233,854,535
Ensembl chr 2:233,833,416...233,854,566 		JBrowse link
G HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 IDA DNA:hypomethylation: CpG islands: RGD PMID:20165882 RGD:14694974 NCBI chr 6:33,064,569...33,080,748
Ensembl chr 6:33,064,569...33,080,775 		JBrowse link
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 susceptibility IAGP associated with Hepatitis B, Chronic;DNA:SNP: :rs9272105(human)
associated with Hepatitis B, Chronic;DNA:SNPs, haplotype: : rs9275572, rs2596542(human) 		RGD PMID:30160782 PMID:24204805 RGD:14398839, RGD:14401561 NCBI chr 6:32,637,406...32,655,272
Ensembl chr 6:32,628,179...32,647,062 		JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 treatment IAGP associated with hepatitis B
associated with hepatitis C;DNA:SNPs,haplotypes 		RGD PMID:27288300 PMID:28921602 RGD:14928325, RGD:14974233 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383 		JBrowse link
G HMGB2 high mobility group box 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20851854 NCBI chr 4:173,331,376...173,334,358
Ensembl chr 4:173,331,376...173,334,432 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase EXP CTD Direct Evidence: marker/mechanism CTD PMID:9207284 PMID:21147110 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 disease_progression IEP RGD PMID:28867541 RGD:14975299 NCBI chr 1:119,747,996...119,768,932
Ensembl chr 1:119,748,002...119,768,905 		JBrowse link
G HMMR hyaluronan mediated motility receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:163,460,632...163,491,941
Ensembl chr 5:163,460,203...163,491,941 		JBrowse link
G HMMR-AS1 HMMR antisense RNA 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:35179300 NCBI chr 5:163,482,604...163,494,058
Ensembl chr 5:163,483,065...163,494,058 		JBrowse link
G HNF1A HNF1 homeobox A treatment IMP human cell line in mouse model RGD PMID:29466992 RGD:14700664 NCBI chr12:120,978,543...121,002,512
Ensembl chr12:120,978,543...121,002,512 		JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha ISO
IEP 		protein:decreased expression:liver: RGD PMID:20876809 PMID:20876809 RGD:12904747, RGD:12904747 NCBI chr20:44,355,699...44,434,596
Ensembl chr20:44,355,699...44,432,845 		JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 IEP protein:increased expression:liver (human) RGD PMID:23633480 RGD:9685423 NCBI chr12:54,280,726...54,287,087
Ensembl chr12:54,280,193...54,287,088 		JBrowse link
G HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 IEP
ISO 		protein:increased expression:liver (human)
mRNA:increased expression:liver (rat) 		RGD PMID:20604928 PMID:23633480 RGD:9685422, RGD:9685423 NCBI chr 7:26,189,927...26,200,746
Ensembl chr 7:26,171,151...26,201,529 		JBrowse link
G HNRNPAB heterogeneous nuclear ribonucleoprotein A/B severity IEP
IMP 		mRNA:increased expression:liver (human)
human gene in a mouse model 		RGD PMID:24638979 PMID:24638979 RGD:10059322, RGD:10059322 NCBI chr 5:178,204,533...178,211,163
Ensembl chr 5:178,204,533...178,211,163 		JBrowse link
G HNRNPD heterogeneous nuclear ribonucleoprotein D IEP
ISO 		protein:increased expression:liver (human)
protein:increased expression:liver (rat) 		RGD PMID:20102719 PMID:22318685 RGD:10042969, RGD:10042977 NCBI chr 4:82,352,498...82,373,991
Ensembl chr 4:82,352,498...82,374,503 		JBrowse link
G HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 IEP protein:increased expression:liver (human) RGD PMID:23633480 RGD:9685423 NCBI chr 5:179,614,178...179,634,784
Ensembl chr 5:179,614,178...179,634,784 		JBrowse link
G HNRNPL heterogeneous nuclear ribonucleoprotein L IDA associated with Hepatitis B RGD PMID:24125732 RGD:9999429 NCBI chr19:38,836,370...38,852,347
Ensembl chr19:38,836,370...38,852,347 		JBrowse link
G HOTAIR HOX transcript antisense RNA EXP CTD Direct Evidence: marker/mechanism CTD PMID:21327457 NCBI chr12:53,962,312...53,974,954
Ensembl chr12:53,962,308...53,975,055 		JBrowse link
G HOXA10 homeobox A10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:27,170,605...27,179,861
Ensembl chr 7:27,170,605...27,180,261 		JBrowse link
G HOXA13 homeobox A13 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:27,194,364...27,200,091
Ensembl chr 7:27,193,503...27,200,091 		JBrowse link
G HOXD9 homeobox D9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:176,122,719...176,124,937
Ensembl chr 2:176,122,719...176,124,937 		JBrowse link
G HP haptoglobin IEP protein:increased expression:saliva
protein:decreased expression:liver (human) 		RGD PMID:31041878 PMID:24259486 RGD:27095881, RGD:152995276 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055 		JBrowse link
G HPRT1 hypoxanthine phosphoribosyltransferase 1 ISO protein:increased activity:hepatoma (rat) RGD PMID:6327016 RGD:5135035 NCBI chr  X:134,460,165...134,500,668
Ensembl chr  X:134,460,165...134,520,513 		JBrowse link
G HRAS HRas proto-oncogene, GTPase treatment EXP
IAGP
ISO
IMP
IEP 		CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hepatocellular cancer
ClinVar Annotator: match by term: Hepatocellular carcinoma
mRNA:increased expression:liver (mouse)
human plasmid in a mouse model
human cells in a mouse model
protein:increased expression:liver (human) 		CTD
ClinVar
RGD		 PMID:8200073 PMID:9311599 PMID:11150980 PMID:12835555 PMID:16155195 More... RGD:14694810, RGD:14694809, RGD:14688055, RGD:14688054 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321 		JBrowse link
G HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr 1:119,414,931...119,423,034
Ensembl chr 1:119,414,931...119,423,035 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 PMID:29698666 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,675 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,305,813 		JBrowse link
G HTATIP2 HIV-1 Tat interactive protein 2 EXP CTD Direct Evidence: therapeutic CTD PMID:16799960 NCBI chr11:20,363,714...20,383,782
Ensembl chr11:20,363,685...20,383,782 		JBrowse link
G HTRA1 HtrA serine peptidase 1 exacerbates
disease_progression 		IEP protein:decreased expression:liver (human)
mRNA:decreased expression:liver (human) 		RGD PMID:20943460 PMID:26403966 RGD:152985524, RGD:152985529 NCBI chr10:122,461,553...122,514,907
Ensembl chr10:122,458,551...122,514,907 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 severity IEP protein:increased expression:serum RGD PMID:26109813 RGD:11056752 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 2:208,236,227...208,255,071
Ensembl chr 2:208,236,229...208,266,074 		JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 disease_progression IEP RGD PMID:24716838 RGD:14985249 NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,477 		JBrowse link
G IER2 immediate early response 2 IEP
IMP 		mRNA, protein:decreased expression:liver (human)
human cells in mouse model 		RGD PMID:32009420 PMID:32009420 RGD:153323326, RGD:153323326 NCBI chr19:13,150,411...13,154,911
Ensembl chr19:13,150,411...13,156,981 		JBrowse link
G IFNA1 interferon alpha 1 susceptibility EXP
IAGP 		CTD Direct Evidence: therapeutic
associated with hepatitis B; DNA:SNP:: ( rs1831583) (human) 		CTD
RGD		 PMID:17088986 PMID:17971768 PMID:18665156 PMID:29080269 RGD:21406429 NCBI chr 9:21,440,439...21,441,316
Ensembl chr 9:21,440,439...21,441,316 		JBrowse link
G IFNA2 interferon alpha 2 susceptibility IAGP associated with hepatitis B; DNA:SNP:enhancer: (rs649053) (human) RGD PMID:29080269 RGD:21406429 NCBI chr 9:21,384,255...21,385,398
Ensembl chr 9:21,384,255...21,385,398 		JBrowse link
G IFNG interferon gamma ISO mRNA:increased expression:liver (mouse) RGD PMID:26569409 RGD:11344640 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IFNL1 interferon lambda 1 ameliorates IMP human protein and cells in mouse model RGD PMID:24769671 RGD:126848750 NCBI chr19:39,296,407...39,298,673
Ensembl chr19:39,296,407...39,298,673 		JBrowse link
G IGBP1 immunoglobulin binding protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21339737 NCBI chr  X:70,133,447...70,166,324
Ensembl chr  X:70,133,447...70,166,324 		JBrowse link
G IGF1 insulin like growth factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
G IGF1R insulin like growth factor 1 receptor susceptibility EXP
IAGP 		CTD Direct Evidence: marker/mechanism
DNA:SNPs, haplotype: : 		CTD
RGD		 PMID:17441810 PMID:23958494 PMID:24758241 RGD:14985227 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530 		JBrowse link
G IGF2 insulin like growth factor 2 susceptibility ISO
IAGP
EXP 		associated with hepatitis B;DNA:SNPs:intron, 3'utr:+2482A>C, +820A>G (human)
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:12532445 PMID:16092956 PMID:17554210 PMID:16750516 RGD:2311523, RGD:14401723 NCBI chr11:2,129,117...2,149,566
Ensembl chr11:2,129,112...2,158,391 		JBrowse link
G IGF2BP1 insulin like growth factor 2 mRNA binding protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:48,996,558...49,056,145
Ensembl chr17:48,997,385...49,056,145 		JBrowse link
G IGF2BP3 insulin like growth factor 2 mRNA binding protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:23,310,209...23,470,491
Ensembl chr 7:23,310,209...23,470,491 		JBrowse link
G IGF2R insulin like growth factor 2 receptor treatment
no_association
disease_progression 		IAGP
IEP
EXP 		DNA:mutation:G1449V (human)
ClinVar Annotator: match by term: Hepatocellular carcinoma
associated with hepatitis B virus; mRNA:decreased expression:liver:
DNA:loss of heterozygosity,mutations:liver:
DNA:loss of heterozygosity:liver
protein:increased expression:serum:
CTD Direct Evidence: marker/mechanism 		ClinVar
CTD
OMIM
RGD		 PMID:9722161 PMID:15057872 PMID:25741868 PMID:7493029 PMID:12736721 More... RGD:1624323, RGD:14985225, RGD:14985222, RGD:14985221, RGD:14985220, RGD:14985219, RGD:14985218 NCBI chr 6:159,969,082...160,111,504
Ensembl chr 6:159,969,082...160,113,507 		JBrowse link
G IGFALS insulin like growth factor binding protein acid labile subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:1,790,413...1,794,908
Ensembl chr16:1,790,413...1,794,971 		JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma treatment ISO
IEP 		protein:decreased expression:liver (human) RGD PMID:29551768 PMID:22922425 PMID:24971483 PMID:17292824 PMID:25173965 More... RGD:153297807, RGD:153305947, RGD:11079569, RGD:153305945, RGD:153305943, RGD:153297813 NCBI chr  X:154,541,238...154,565,046
Ensembl chr  X:154,541,199...154,565,046 		JBrowse link
G IKZF1 IKAROS family zinc finger 1 ameliorates IEP protein:increased expression:liver (human) RGD PMID:25301737 RGD:150540326 NCBI chr 7:50,303,455...50,405,101
Ensembl chr 7:50,304,068...50,405,101 		JBrowse link
G IL10 interleukin 10 treatment ISO
IAGP 		RGD PMID:23822114 PMID:26890368 RGD:7365006, RGD:14975171 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL12A interleukin 12A susceptibility IAGP associated with hepatitis C;DNA:SNP:3'UTR: rs568408( G>A)(human)
associated with hepatitis B; DNA:SNP, haplotype:3′UTR :rs568408(human) 		RGD PMID:27819525 PMID:26631030 PMID:20521253 RGD:25440490, RGD:25440501, RGD:25440491 NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019 		JBrowse link
G IL15RA interleukin 15 receptor subunit alpha disease_progression IEP mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr10:5,948,900...5,978,741
Ensembl chr10:5,943,639...5,978,187 		JBrowse link
G IL18 interleukin 18 severity
disease_progression
susceptibility 		IAGP
IEP 		associated with hepatitis C;DNA:SNPs, haplotype:promoter:-607C>A, -137G>C(human)
associated with hepatitis B, chronic;DNA:SNP:promoter:-607C>A(human)
DNA:SNP:promoter:-137G>C(rs187238)(human) 		RGD PMID:29341496 PMID:27470888 PMID:27429592 PMID:26893476 RGD:14695526, RGD:14696663, RGD:14695540, RGD:11538094 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,251...112,164,096 		JBrowse link
G IL18R1 interleukin 18 receptor 1 IEP
ISO 		mRNA:decreased expression:liver RGD PMID:26893476 PMID:26893476 RGD:11538094, RGD:11538094 NCBI chr 2:102,355,796...102,398,776
Ensembl chr 2:102,311,529...102,398,777 		JBrowse link
G IL1B interleukin 1 beta susceptibility IAGP DNA:polymorphism:promoter:-31T>C (human) RGD PMID:21653279 RGD:7401222 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1RAP interleukin 1 receptor accessory protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:190,514,085...190,659,750
Ensembl chr 3:190,514,051...190,659,750 		JBrowse link
G IL1RN interleukin 1 receptor antagonist EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL2 interleukin 2 treatment IDA RGD PMID:10933975 PMID:9449371 RGD:8693323, RGD:14747035 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL21 interleukin 21 IAGP associated with hepatitis B;DNA:SNPS, haplotype:(rs13143866, rs2221903, rs907715) (human) RGD PMID:25892873 RGD:127285359 NCBI chr 4:122,610,108...122,621,066
Ensembl chr 4:122,610,108...122,621,066 		JBrowse link
G IL32 interleukin 32 IEP associated with hepatitis C, liver cirrhosis:mRNA:increased expression:liver (human) RGD PMID:17696935 RGD:150340754 NCBI chr16:3,065,403...3,069,530
Ensembl chr16:3,065,297...3,082,192 		JBrowse link
G IL6 interleukin 6 treatment
disease_progression 		EXP
ISO
IAGP 		CTD Direct Evidence: marker/mechanism
mRNA,protein:increased expression:liver, blood serum (mouse)
DNA:SNP: :rs2069852 (human) 		CTD
RGD		 PMID:17615358 PMID:20818158 PMID:26297436 PMID:27022031 PMID:29486150 More... RGD:127285672, RGD:11344640, RGD:14975289 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IL6ST interleukin 6 cytokine family signal transducer ISO RGD PMID:15780071 RGD:1626706 NCBI chr 5:55,935,095...55,994,963
Ensembl chr 5:55,935,095...55,995,022 		JBrowse link
G ING3 inhibitor of growth family member 3 treatment ISO RGD PMID:25156538 RGD:9587823 NCBI chr 7:120,950,777...120,977,216
Ensembl chr 7:120,950,763...120,977,216 		JBrowse link
G INMT indolethylamine N-methyltransferase EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 7:30,752,135...30,757,602
Ensembl chr 7:30,697,985...30,757,602 		JBrowse link
G INPP4B inositol polyphosphate-4-phosphatase type II B EXP CTD Direct Evidence: marker/mechanism CTD PMID:29415082 NCBI chr 4:142,023,160...142,846,535
Ensembl chr 4:142,023,160...142,847,432 		JBrowse link
G INS insulin HEP associated with Chronic Hepatitis C;mRNA:decreased expression:liver (human) RGD PMID:33132693 RGD:150340613 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221 		JBrowse link
G INS-IGF2 INS-IGF2 readthrough EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209 		JBrowse link
G INSR insulin receptor IEP
ISO 		mRNA, protein:increased expression:liver (human, rat)
human cells in a mouse model 		RGD PMID:23633480 PMID:29610518 RGD:9685423, RGD:14700930 NCBI chr19:7,112,265...7,294,414
Ensembl chr19:7,112,255...7,294,414 		JBrowse link
G IQGAP1 IQ motif containing GTPase activating protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20977743 NCBI chr15:90,388,242...90,502,239
Ensembl chr15:90,388,242...90,502,239 		JBrowse link
G IQGAP2 IQ motif containing GTPase activating protein 2 EXP
ISS 		CTD Direct Evidence: marker/mechanism
OMIM:114550 		CTD
MouseDO		 PMID:20977743 NCBI chr 5:76,403,285...76,708,132
Ensembl chr 5:76,403,285...76,708,132 		JBrowse link
G IQGAP3 IQ motif containing GTPase activating protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:156,525,405...156,572,565
Ensembl chr 1:156,525,405...156,572,604 		JBrowse link
G IRF2 interferon regulatory factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22561517 NCBI chr 4:184,387,729...184,474,550
Ensembl chr 4:184,385,702...184,474,558 		JBrowse link
G IRS1 insulin receptor substrate 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:1311924 PMID:23958494 NCBI chr 2:226,731,312...226,799,820
Ensembl chr 2:226,731,312...226,799,820 		JBrowse link
G IRS2 insulin receptor substrate 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16127164 NCBI chr13:109,752,695...109,786,583
Ensembl chr13:109,752,695...109,786,583 		JBrowse link
G ISG15 ISG15 ubiquitin like modifier EXP CTD Direct Evidence: marker/mechanism CTD PMID:28919514 NCBI chr 1:1,013,497...1,014,540
Ensembl chr 1:1,001,138...1,014,540 		JBrowse link
G ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr 3:52,794,796...52,808,797
Ensembl chr 3:52,794,768...52,808,799 		JBrowse link
G ITIH4 inter-alpha-trypsin inhibitor heavy chain 4 disease_progression IEP associated with hepatitis B;protein:decreased expression:serum RGD PMID:24836184 RGD:40903002 NCBI chr 3:52,812,962...52,830,672
Ensembl chr 3:52,812,962...52,830,688 		JBrowse link
G JAG1 jagged canonical Notch ligand 1 IEP protein:increased expression:liver RGD PMID:30660174 RGD:14694832 NCBI chr20:10,637,684...10,673,999
Ensembl chr20:10,637,684...10,673,999 		JBrowse link
G JAK1 Janus kinase 1 IAGP RGD PMID:23788652 RGD:150524353 NCBI chr 1:64,833,229...65,067,746
Ensembl chr 1:64,833,223...65,067,754 		JBrowse link
G JAK2 Janus kinase 2 severity
treatment
ameliorates
exacerbates 		IEP
ISO 		mRNA:decreased expression:liver (human)
L-JAK2 KO
associated with Diseases of the Aged and non-alcoholic fatty liver disease
protein:increased phosphorylation:liver (mouse)
protein:increased phosphorylation:liver (human) 		RGD PMID:25420511 PMID:29486150 PMID:28100771 PMID:31393852 PMID:22821478 More... RGD:18182928, RGD:127285672, RGD:127285675, RGD:127285655, RGD:127285621, RGD:125097525 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948 		JBrowse link
G JDP2 Jun dimerization protein 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20214788 NCBI chr14:75,426,943...75,474,107
Ensembl chr14:75,427,716...75,474,111 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:20214788 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G JUND JunD proto-oncogene, AP-1 transcription factor subunit IEP associated with HBV;protein:increased expression:liver (human) RGD PMID:15927205 RGD:153297768 NCBI chr19:18,279,694...18,281,622
Ensembl chr19:18,279,694...18,281,622 		JBrowse link
G KAT2B lysine acetyltransferase 2B severity IEP protein:decreased expression:liver (human) RGD PMID:23643089 RGD:9590314 NCBI chr 3:20,040,446...20,154,404
Ensembl chr 3:20,040,446...20,154,404 		JBrowse link
G KBTBD11 kelch repeat and BTB domain containing 11 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:1,973,677...2,006,936
Ensembl chr 8:1,973,677...2,006,936 		JBrowse link
G KCNH1 potassium voltage-gated channel subfamily H member 1 IEP protein:increased expression:liver (human) RGD PMID:17022810 RGD:9693723 NCBI chr 1:210,678,314...211,134,148
Ensembl chr 1:210,676,823...211,134,165 		JBrowse link
G KCNN2 potassium calcium-activated channel subfamily N member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:114,055,978...114,496,496
Ensembl chr 5:114,055,926...114,496,500 		JBrowse link
G KDM1A lysine demethylase 1A severity IEP mRNA, protein:increased expression:liver (human) RGD PMID:23236241 RGD:9681002 NCBI chr 1:23,019,468...23,083,689
Ensembl chr 1:23,019,443...23,083,689 		JBrowse link
G KDM3A lysine demethylase 3A IEP mRNA:increased expression:liver (human) RGD PMID:21607773 RGD:9590222 NCBI chr 2:86,437,044...86,492,716
Ensembl chr 2:86,440,647...86,492,716 		JBrowse link
G KDM5C lysine demethylase 5C exacerbates IEP protein:increased expression:liver (human) RGD PMID:26503415 RGD:11530160 NCBI chr  X:53,176,277...53,225,207
Ensembl chr  X:53,176,277...53,225,422 		JBrowse link
G KDM6A lysine demethylase 6A ameliorates IMP human cells in a mouse model RGD PMID:32765772 RGD:150429729 NCBI chr  X:44,873,188...45,112,779
Ensembl chr  X:44,873,188...45,112,779 		JBrowse link
G KDM8 lysine demethylase 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:27,203,526...27,221,768
Ensembl chr16:27,203,508...27,221,768 		JBrowse link
G KDR kinase insert domain receptor treatment
disease_progression 		IAGP
IEP 		DNA:SNPs: :rs1870377, rs2071559, rs2305948 (human)
associated with alcoholic liver cirrhosis;DNA:SNP: :1416A>T (human)
protein:decreased expression:liver
protein:increased expression:liver 		RGD PMID:25182707 PMID:24445728 PMID:23660204 PMID:25333267 PMID:19177438 RGD:126848806, RGD:126848814, RGD:126848813, RGD:126848812, RGD:126848810 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595 		JBrowse link
G KIF11 kinesin family member 11 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:92,593,130...92,655,395
Ensembl chr10:92,574,105...92,655,395 		JBrowse link
G KIF14 kinesin family member 14 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:200,551,497...200,620,751
Ensembl chr 1:200,551,497...200,620,751 		JBrowse link
G KIF15 kinesin family member 15 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:44,761,794...44,868,687
Ensembl chr 3:44,761,721...44,873,376 		JBrowse link
G KIF18A kinesin family member 18A EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:28,020,619...28,108,156
Ensembl chr11:28,020,619...28,108,156 		JBrowse link
G KIF18B kinesin family member 18B EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:44,924,711...44,947,773
Ensembl chr17:44,924,709...44,947,773 		JBrowse link
G KIF1B kinesin family member 1B severity
susceptibility 		IEP
IAGP 		mRNA, protein:decreased expression:liver (human)
DNA:snp:intron:c.2537+518A>G (rs17401966) (human) 		RGD PMID:26217094 PMID:27122668 RGD:11052488, RGD:12738461 NCBI chr 1:10,210,570...10,381,603
Ensembl chr 1:10,210,570...10,381,603 		JBrowse link
G KIF20A kinesin family member 20A EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:138,179,112...138,187,723
Ensembl chr 5:138,178,719...138,187,723 		JBrowse link
G KIF23 kinesin family member 23 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:69,414,349...69,448,427
Ensembl chr15:69,414,246...69,448,427 		JBrowse link
G KIF2C kinesin family member 2C EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:44,739,837...44,767,767
Ensembl chr 1:44,739,818...44,767,767 		JBrowse link
G KIF4A kinesin family member 4A EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:70,290,104...70,420,886
Ensembl chr  X:70,290,104...70,420,886 		JBrowse link
G KIFC1 kinesin family member C1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:33,391,461...33,409,896
Ensembl chr 6:33,391,823...33,409,896 		JBrowse link
G KIR3DS1 killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1 susceptibility IAGP associated with hepatitis C;DNA:deletion, haplotype: (human) RGD PMID:25700262 RGD:38676455
G KLF4 KLF transcription factor 4 disease_progression
treatment 		IEP
IDA 		RGD PMID:22677193 PMID:22677193 RGD:14402023, RGD:14402023 NCBI chr 9:107,484,852...107,489,769
Ensembl chr 9:107,484,852...107,490,482 		JBrowse link
G KLRF1 killer cell lectin like receptor F1 disease_progression IEP mRNA:decreased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr12:9,800,052...9,845,005
Ensembl chr12:9,827,481...9,845,007 		JBrowse link
G KMT2A lysine methyltransferase 2A EXP CTD Direct Evidence: marker/mechanism CTD PMID:22634756 NCBI chr11:118,436,492...118,526,832
Ensembl chr11:118,436,456...118,526,832 		JBrowse link
G KMT2B lysine methyltransferase 2B IAGP
EXP 		DNA:insertions, translocations:intron:IVS3, multiple (human)
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:22634754 PMID:18320596 RGD:9588597 NCBI chr19:35,718,003...35,738,878
Ensembl chr19:35,717,973...35,738,880 		JBrowse link
G KMT2C lysine methyltransferase 2C EXP CTD Direct Evidence: marker/mechanism CTD PMID:22634756 NCBI chr 7:152,134,925...152,436,003
Ensembl chr 7:152,134,922...152,436,644 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase induced ISO
IEP
EXP 		aflatoxin B1 induced:DNA:transversion,transition mutations:cds:
mRNA,protein:increased expression:liver
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:11286481 PMID:11563603 PMID:8446626 PMID:29275358 RGD:11568697, RGD:14398750 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936 		JBrowse link
G KRT18 keratin 18 ISS OMIM:114550 MouseDO NCBI chr12:52,948,855...52,952,906
Ensembl chr12:52,948,871...52,952,906 		JBrowse link
G LCAT lecithin-cholesterol acyltransferase EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:67,939,750...67,944,120
Ensembl chr16:67,939,750...67,944,131 		JBrowse link
G LECT2 leukocyte cell derived chemotaxin 2 ameliorates ISO
IMP
IEP 		protein:increased expression:blood serum (mouse)
human cells in mouse model
protein:increased expression:blood serum (human) 		RGD PMID:24892551 PMID:21394108 PMID:24892551 RGD:153323333, RGD:153323335, RGD:153323333 NCBI chr 5:135,946,904...135,954,983
Ensembl chr 5:135,922,279...135,954,983 		JBrowse link
G LEP leptin susceptibility
severity 		IAGP
IEP 		DNA:SNP:enhancer:-2548G>A (rs7799039) (human)
protein:increased expression:liver (human) 		RGD PMID:28452232 PMID:18573568 RGD:15039399, RGD:25330348 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G LEPR leptin receptor susceptibility IAGP associated with Hepatitis B, Chronic;DNA:missense mutations:cds:p.Q223R, p.K109R (human) RGD PMID:23090836 RGD:21079466 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559 		JBrowse link
G LETM1 leucine zipper and EF-hand containing transmembrane protein 1 EXP CTD Direct Evidence: therapeutic CTD PMID:23392203 NCBI chr 4:1,811,479...1,856,156
Ensembl chr 4:1,811,479...1,856,156 		JBrowse link
G LIFR LIF receptor subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:38,474,668...38,608,403
Ensembl chr 5:38,474,668...38,608,354 		JBrowse link
G LILRB5 leukocyte immunoglobulin like receptor B5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr19:54,249,421...54,257,273
Ensembl chr19:54,249,421...54,257,301 		JBrowse link
G LINC00221 long intergenic non-protein coding RNA 221 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:106,482,439...106,495,515
Ensembl chr14:106,482,435...106,521,073 		JBrowse link
G LOC110806263 TERT 5' regulatory region IAGP ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar PMID:28492532 PMID:28677271 NCBI chr 5:1,294,628...1,298,988 JBrowse link
G LOC126806658 BRD4-independent group 4 enhancer GRCh37_chr3:41265899-41267098 IAGP ClinVar Annotator: match by term: Hepatocellular carcinoma
ClinVar Annotator: match by term: Hepatocellular cancer 		ClinVar PMID:10192393 PMID:10435629 PMID:23033978 PMID:24614104 PMID:25326635 More... NCBI chr 3:41,224,408...41,225,607 JBrowse link
G LOC126806659 BRD4-independent group 4 enhancer GRCh37_chr3:41274918-41276117 IAGP ClinVar Annotator: match by term: Hepatocellular carcinoma
ClinVar Annotator: match by term: Hepatocellular cancer 		ClinVar PMID:23033978 PMID:24614104 PMID:25326669 PMID:25741868 PMID:26350204 More... NCBI chr 3:41,233,427...41,234,626 JBrowse link
G LOC129994371 ATAC-STARR-seq lymphoblastoid active region 22910 IAGP ClinVar Annotator: match by term: Hepatocellular cancer ClinVar PMID:25741868 PMID:28492532 NCBI chr 5:112,707,478...112,707,537 JBrowse link
G LOC129997612 ATAC-STARR-seq lymphoblastoid silent region 17757 IAGP ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar PMID:25741868 NCBI chr 6:159,969,273...159,969,552 JBrowse link
G LOXL3 lysyl oxidase like 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:35841383 NCBI chr 2:74,532,258...74,555,702
Ensembl chr 2:74,532,258...74,555,690 		JBrowse link
G LPA lipoprotein(a) EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:160,531,482...160,664,275
Ensembl chr 6:160,531,482...160,664,275 		JBrowse link
G LPAR1 lysophosphatidic acid receptor 1 ISO RGD PMID:19000703 RGD:2317680 NCBI chr 9:110,873,263...111,038,998
Ensembl chr 9:110,873,263...111,038,470 		JBrowse link
G LRAT lecithin retinol acyltransferase EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:154,740,838...154,753,120
Ensembl chr 4:154,626,945...154,753,120 		JBrowse link
G LRP1B LDL receptor related protein 1B exacerbates IEP
IAGP 		protein:increased expression:liver (human)
DNA:mutations:multiple: (human) 		RGD PMID:33324588 PMID:33391418 RGD:150429776, RGD:150429785 NCBI chr 2:140,231,423...142,131,016
Ensembl chr 2:140,231,423...142,131,016 		JBrowse link
G LRRC1 leucine rich repeat containing 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:53,795,005...53,924,125
Ensembl chr 6:53,794,497...53,924,125 		JBrowse link
G LRRC56 leucine rich repeat containing 56 IAGP ClinVar Annotator: match by term: Hepatocellular cancer ClinVar PMID:16170316 PMID:16372351 PMID:16443854 PMID:16835863 PMID:17601930 More... NCBI chr11:506,462...554,912
Ensembl chr11:537,527...554,912 		JBrowse link
G LRRC59 leucine rich repeat containing 59 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr17:50,381,238...50,397,523
Ensembl chr17:50,375,059...50,397,523 		JBrowse link
G LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:10,556,966...10,568,665
Ensembl chr11:10,556,966...10,611,689 		JBrowse link
G LZTR1 leucine zipper like post translational regulator 1 IAGP DNA:missense mutation:cds, liver (human) RGD PMID:28622513 RGD:151893487 NCBI chr22:20,982,297...20,999,032
Ensembl chr22:20,982,269...20,999,032 		JBrowse link
G MAD2L1 mitotic arrest deficient 2 like 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 PMID:39316419 NCBI chr 4:120,055,623...120,066,848
Ensembl chr 4:120,055,623...120,066,858 		JBrowse link
G MAGEA1 MAGE family member A1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:153,179,284...153,183,880
Ensembl chr  X:153,179,284...153,183,880 		JBrowse link
G MAGEA3 MAGE family member A3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:152,698,794...152,702,347
Ensembl chr  X:152,698,767...152,702,347 		JBrowse link
G MAGEA6 MAGE family member A6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:152,766,136...152,769,689
Ensembl chr  X:152,766,136...152,769,716 		JBrowse link
G MAGEC2 MAGE family member C2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:142,202,342...142,205,290
Ensembl chr  X:142,202,342...142,205,290 		JBrowse link
G MALAT1 metastasis associated lung adenocarcinoma transcript 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26735578 NCBI chr11:65,497,738...65,506,516
Ensembl chr11:65,497,606...65,508,073 		JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 exacerbates IEP
ISO 		mRNA:increased expression:liver (human)
protein:increased expression:liver, cytosol (rat) 		RGD PMID:33553243 PMID:9397988 RGD:150530475, RGD:150530477 NCBI chr19:4,090,321...4,124,122
Ensembl chr19:4,090,321...4,124,122 		JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 IEP protein:decreased expression:liver (human) RGD PMID:32850377 RGD:150429765 NCBI chr17:12,020,877...12,143,828
Ensembl chr17:12,020,829...12,143,830 		JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 exacerbates IEP mRNA:decreased expression:liver (human) RGD PMID:31310010 RGD:150573714 NCBI chr 5:56,815,549...56,896,152
Ensembl chr 5:56,815,549...56,896,152 		JBrowse link
G MAP3K8 mitogen-activated protein kinase kinase kinase 8 ameliorates ISO RGD PMID:26560698 RGD:11342977 NCBI chr10:30,434,021...30,461,833
Ensembl chr10:30,434,021...30,461,833 		JBrowse link
G MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 ameliorates
treatment
severity 		IMP
IDA 		human cell line in a mouse model
human recombinant gene and cell line in a mouse model 		RGD PMID:21196414 PMID:31922225 PMID:27010469 RGD:151347673, RGD:151347839, RGD:151347674 NCBI chr 2:101,697,707...101,894,690
Ensembl chr 2:101,696,850...101,894,690 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 IEP protein:increased expression:liver RGD PMID:27468214 RGD:401976278 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 treatment
exacerbates 		ISO RGD PMID:25216638 PMID:23271722 RGD:151665347, RGD:151665348 NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,752...36,122,511 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 ameliorates IEP protein:decreased phosphorylation:liver (human) RGD PMID:33875785 RGD:150340688 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MAPT microtubule associated protein tau EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:45,894,554...46,028,334
Ensembl chr17:45,894,527...46,028,334 		JBrowse link
G MARCO macrophage receptor with collagenous structure EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:118,942,194...118,994,660
Ensembl chr 2:118,942,194...118,994,660 		JBrowse link
G MAT1A methionine adenosyltransferase 1A EXP CTD Direct Evidence: marker/mechanism CTD PMID:12060674 NCBI chr10:80,271,820...80,289,658
Ensembl chr10:80,271,820...80,289,658 		JBrowse link
G MBL2 mannose binding lectin 2 severity
susceptibility
no_association 		IAGP
IEP 		associated with hepatitis C;DNA:SNP: :221C>G(rs709620)(human)
associated with hepatitis B;DNA:SNP:exon:
protein:decreased expression:plasma
DNA:SNPs:promoter:rs7096206(human)
associated with viral hepatitis;DNA:polymorphisms:exon:
associated with hepatitis B-related cirrhosis;DNA:SNP: :rs11003123(G>A)(human) 		RGD PMID:21733090 PMID:26857650 PMID:27557564 PMID:25787238 PMID:18221301 More... RGD:14696813, RGD:14696836, RGD:14696835, RGD:14696833, RGD:14696829, RGD:14696814 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G MBTPS1 membrane bound transcription factor peptidase, site 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:14563831 NCBI chr16:84,053,763...84,116,942
Ensembl chr16:84,053,761...84,116,942 		JBrowse link
G MBTPS2 membrane bound transcription factor peptidase, site 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:14563831 NCBI chr  X:21,839,617...21,885,423
Ensembl chr  X:21,839,617...21,885,423 		JBrowse link
G MCM10 minichromosome maintenance 10 replication initiation factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:13,161,558...13,211,110
Ensembl chr10:13,161,558...13,211,110 		JBrowse link
G MCM2 minichromosome maintenance complex component 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:127,598,411...127,622,436
Ensembl chr 3:127,598,223...127,622,436 		JBrowse link
G MCM7 minichromosome maintenance complex component 7 susceptibility IAGP
IEP 		associated with hepatitis B;DNA:SNP:promoter: (rs999885) (human)
associated with hepatitis B;miRNA:increased expression:liver (human) 		RGD PMID:24416400 PMID:27298561 RGD:15042885, RGD:15042853 NCBI chr 7:100,092,728...100,101,397
Ensembl chr 7:100,092,233...100,101,940 		JBrowse link
G MCM9 minichromosome maintenance 9 homologous recombination repair factor ISS OMIM:114550 MouseDO NCBI chr 6:118,813,455...118,935,159
Ensembl chr 6:118,813,442...118,935,162 		JBrowse link
G MDM2 MDM2 proto-oncogene susceptibility IAGP DNA:transversion:promoter:g.-309T>G (human) RGD PMID:20019189 RGD:2317357 NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544 		JBrowse link
G ME1 malic enzyme 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr 6:83,210,402...83,431,051
Ensembl chr 6:83,210,402...83,431,051 		JBrowse link
G MECP2 methyl-CpG binding protein 2 ISO
EXP 		mRNA, protein:increased expression:liver
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:26189965 PMID:11844796 RGD:2289670 NCBI chr  X:154,021,573...154,097,717
Ensembl chr  X:154,021,573...154,137,103 		JBrowse link
G MED1 mediator complex subunit 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20007298 NCBI chr17:39,404,285...39,451,263
Ensembl chr17:39,404,285...39,451,272 		JBrowse link
G MELK maternal embryonic leucine zipper kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:36,572,895...36,677,682
Ensembl chr 9:36,572,862...36,677,683 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase susceptibility
severity 		ISO
IAGP
IEP
EXP 		protein:increased expression:liver (rat)
ClinVar Annotator: match by term: Hepatocellular cancer
protein:increased expression:liver (human)
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver, carcinoma (human) 		OMIM
ClinVar
CTD
RGD		 PMID:21774103 PMID:21970370 PMID:22703879 PMID:24728327 PMID:25741868 More... RGD:2317495, RGD:152995524, RGD:152995524, RGD:2317575, RGD:1600123 NCBI chr 7:116,672,196...116,798,377
Ensembl chr 7:116,672,196...116,798,377 		JBrowse link
G MFSD2A MFSD2 lysolipid transporter A, lysophospholipid EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:39,955,145...39,969,956
Ensembl chr 1:39,955,112...39,969,968 		JBrowse link
G MICA MHC class I polypeptide-related sequence A EXP CTD Direct Evidence: marker/mechanism CTD PMID:21499248 NCBI chr 6:31,400,711...31,415,315
Ensembl chr 6:31,399,784...31,415,315 		JBrowse link
G MIR106B microRNA 106b severity
disease_progression 		IEP miRNA:decreased expression:liver (human)
miRNA:increased expression:liver (human)
miRNA:increased expression:serum (human)
miRNA:increased expression:plasma (human) 		RGD PMID:28958640 PMID:31406464 PMID:28611524 PMID:25894380 RGD:15042874, RGD:15042877, RGD:15042876, RGD:15042875 NCBI chr 7:100,093,993...100,094,074
Ensembl chr 7:100,093,993...100,094,074 		JBrowse link
G MIR107 microRNA 107 treatment
onset 		IEP RNA:increased expression:liver:
RNA:decreased expression:liver: 		RGD PMID:30738047 PMID:28079796 PMID:26191213 PMID:27773820 RGD:14975277, RGD:14975300, RGD:11066920, RGD:14975278 NCBI chr10:89,592,747...89,592,827
Ensembl chr10:89,592,747...89,592,827 		JBrowse link
G MIR122 microRNA 122 severity EXP
IEP
IMP 		CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:blood (human)
protein:decreased expression:liver (human)
associated with hepatitis B; miRNA:decreased expression:liver 		CTD
RGD		 PMID:16924677 PMID:27528885 PMID:19584283 PMID:25422324 PMID:25269820 RGD:151361113, RGD:151356981, RGD:14401603, RGD:14394424 NCBI chr18:58,451,074...58,451,158
Ensembl chr18:58,451,074...58,451,158 		JBrowse link
G MIR125A microRNA 125a treatment
severity 		ISO
IEP 		RNA:increased expression:liver: RGD PMID:30257386 PMID:29951066 PMID:30257386 RGD:21403677, RGD:21403679, RGD:21403677 NCBI chr19:51,693,254...51,693,339
Ensembl chr19:51,693,254...51,693,339 		JBrowse link
G MIR127 microRNA 127 IEP miRNA:decreased expression:liver (human) RGD PMID:24854842 RGD:152995355 NCBI chr14:100,882,979...100,883,075
Ensembl chr14:100,882,979...100,883,075 		JBrowse link
G MIR130B microRNA 130b severity IEP miRNA:increased expression:liver RGD PMID:25387077 RGD:14694845 NCBI chr22:21,653,304...21,653,385
Ensembl chr22:21,653,304...21,653,385 		JBrowse link
G MIR133A1 microRNA 133a-1 disease_progression IEP
IMP 		mRNA:decreased expression:liver (human)
human cells in mouse model 		RGD PMID:30086463 PMID:30086463 RGD:153344517, RGD:153344517 NCBI chr18:21,825,698...21,825,785
Ensembl chr18:21,825,698...21,825,785 		JBrowse link
G MIR133B microRNA 133b severity IEP mRNA:decreased expression:liver(human) RGD PMID:30391496 RGD:155804298 NCBI chr 6:52,148,923...52,149,041
Ensembl chr 6:52,148,923...52,149,041 		JBrowse link
G MIR136 microRNA 136 exacerbates IEP RNA:decreased expression:liver (human) RGD PMID:28849100 RGD:153345547 NCBI chr14:100,884,702...100,884,783
Ensembl chr14:100,884,702...100,884,783 		JBrowse link
G MIR139 microRNA 139 IEP RNA:decreased expression:liver (human) RGD PMID:30710422 RGD:153344549 NCBI chr11:72,615,063...72,615,130
Ensembl chr11:72,615,063...72,615,130 		JBrowse link
G MIR145 microRNA 145 severity IEP miRNA:decreased expression:liver (human) RGD PMID:30572504 RGD:15039395 NCBI chr 5:149,430,646...149,430,733
Ensembl chr 5:149,430,646...149,430,733 		JBrowse link
G MIR146A microRNA 146a sexual_dimorphism
susceptibility 		IAGP associated with hepatitis B;miRNA:SNP:exon: (rs2910164) (human)
associated with hepatitis B;miRNA:SNP: (human) 		RGD PMID:18711148 PMID:24615520 PMID:24816919 RGD:126925148, RGD:126925187, RGD:126925158 NCBI chr 5:160,485,352...160,485,450
Ensembl chr 5:160,485,352...160,485,450 		JBrowse link
G MIR150 microRNA 150 IEP mRNA:decreased expression:liver (human) RGD PMID:30205391 RGD:153344577 NCBI chr19:49,500,785...49,500,868
Ensembl chr19:49,500,785...49,500,868 		JBrowse link
G MIR152 microRNA 152 disease_progression IEP miRNA:decreased expression:liver RGD PMID:30967300 PMID:26531720 RGD:19165146, RGD:21066331 NCBI chr17:48,037,161...48,037,247
Ensembl chr17:48,037,161...48,037,247 		JBrowse link
G MIR154 microRNA 154 IEP RNA:decreased expression:liver (human) RGD PMID:33195697 RGD:152995478 NCBI chr14:101,059,755...101,059,838
Ensembl chr14:101,059,755...101,059,838 		JBrowse link
G MIR155 microRNA 155 disease_progression IEP
IAGP
IMP 		associated with hepatitis C;DNA:SNP: :rs767649 (human)
miRNA:increased expression:serum
miRNA:decreased expression:peripheral blood mononuclear cell 		RGD PMID:27035278 PMID:27531892 PMID:29528577 PMID:30710754 PMID:28074870 More... RGD:21079433, RGD:25671465, RGD:24922222, RGD:21081523, RGD:21079477, RGD:21079433 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044 		JBrowse link
G MIR181C microRNA 181c IEP miRNA:decreased expression:liver (human) RGD PMID:31114379 RGD:15042894 NCBI chr19:13,874,699...13,874,808
Ensembl chr19:13,874,699...13,874,808 		JBrowse link
G MIR18A microRNA 18a severity IEP miRNA:increased expression:liver (human)
associated with Hepatitis C, Chronic;miRNA:increased expression:serum (human)
associated with hepatitis B;miRNA:increased expression:liver (human) 		RGD PMID:19027010 PMID:29455432 PMID:24975878 PMID:30191950 PMID:30519035 RGD:15039398, RGD:15039404, RGD:15039401, RGD:15039389, RGD:15039400 NCBI chr13:91,350,751...91,350,821
Ensembl chr13:91,350,751...91,350,821 		JBrowse link
G MIR18B microRNA 18b severity IEP miRNA:increased expression:liver (human) RGD PMID:23496901 RGD:15039403 NCBI chr  X:134,170,041...134,170,111
Ensembl chr  X:134,170,041...134,170,111 		JBrowse link
G MIR193A microRNA 193a disease_progression
exacerbates 		IEP
IDA 		miRNA:decreased expression:liver (human)
DNA:hypomethylation
RNA:increased expression:blood serum (human) 		RGD PMID:26263159 PMID:28036298 PMID:32960907 PMID:30710422 RGD:11070076, RGD:153344564, RGD:153344563, RGD:153344549 NCBI chr17:31,559,996...31,560,083
Ensembl chr17:31,559,996...31,560,083 		JBrowse link
G MIR195 microRNA 195 severity IEP
IMP 		miRNA:decreased expression:liver (human)
miRNA:decreased expression:liver (mouse) 		RGD PMID:25607636 PMID:25607636 RGD:15042896, RGD:15042896 NCBI chr17:7,017,615...7,017,701
Ensembl chr17:7,017,615...7,017,701 		JBrowse link
G MIR196A2 microRNA 196a-2 susceptibility IAGP associated with hepatitis B, chronic; DNA:SNP: : (rs12304647)
DNA:SNP: : (rs11614913) 		RGD PMID:24248733 PMID:21692953 RGD:14401594, RGD:14401595 NCBI chr12:53,991,738...53,991,847
Ensembl chr12:53,991,738...53,991,847 		JBrowse link
G MIR199B microRNA 199b disease_progression IEP miRNA:decreased expression:liver RGD PMID:30536310 RGD:14694833 NCBI chr 9:128,244,721...128,244,830
Ensembl chr 9:128,244,721...128,244,830 		JBrowse link
G MIR200B microRNA 200b treatment
disease_progression 		IEP
IDA
IMP 		mRNA:decreased expression:liver
DNA:hypermethylation:promoter 		RGD PMID:26919246 PMID:28383782 PMID:28383782 PMID:28383782 PMID:26919246 More... RGD:14928318, RGD:14928322, RGD:14928322, RGD:14928322, RGD:14928318, RGD:14928318 NCBI chr 1:1,167,104...1,167,198
Ensembl chr 1:1,167,104...1,167,198 		JBrowse link
G MIR20A microRNA 20a IEP associated with Human Viral Hepatitis RGD PMID:30623908 RGD:25823145 NCBI chr13:91,351,065...91,351,135
Ensembl chr13:91,351,065...91,351,135 		JBrowse link
G MIR21 microRNA 21 treatment
severity 		IEP miRNA:increased expression:liver RGD PMID:20447717 PMID:21749846 PMID:24963487 RGD:14695022, RGD:41404642, RGD:40925952 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G MIR212 microRNA 212 disease_progression
ameliorates 		IEP
IDA 		RGD PMID:25965836 PMID:25965836 RGD:11054501, RGD:11054501 NCBI chr17:2,050,271...2,050,380
Ensembl chr17:2,050,271...2,050,380 		JBrowse link
G MIR22 microRNA 22 severity
disease_progression 		IEP in male; RNA:increased expression:liver: RGD PMID:23766411 PMID:21750200 PMID:27811373 RGD:14700874, RGD:14700876, RGD:14700875 NCBI chr17:1,713,903...1,713,987
Ensembl chr17:1,713,903...1,713,987 		JBrowse link
G MIR221 microRNA 221 disease_progression
treatment 		IEP
ISO
IMP 		RGD PMID:25817558 PMID:31801250 PMID:28096271 PMID:28096271 PMID:28096271 More... RGD:11086123, RGD:151893509, RGD:18337275, RGD:18337275, RGD:18337275, RGD:18337273, RGD:18337267, RGD:18337267 NCBI chr  X:45,746,157...45,746,266
Ensembl chr  X:45,746,157...45,746,266 		JBrowse link
G MIR222 microRNA 222 disease_progression
severity 		IEP RGD PMID:24124720 PMID:20103675 RGD:151709003, RGD:151709004 NCBI chr  X:45,747,015...45,747,124
Ensembl chr  X:45,747,015...45,747,124 		JBrowse link
G MIR223 microRNA 223 disease_progression ISO
IEP 		associated with high-fat diet,
RNA:increased expression:serum:
associated with Chronic Hepatitis B; RNA:decreased expression:serum:
associated with Chronic HepatitisC; RNA:decreased expression:serum: 		RGD PMID:30964207 PMID:21229610 PMID:24595450 PMID:25391771 PMID:28982915 RGD:21408549, RGD:21408591, RGD:21408583, RGD:21408580, RGD:21408578 NCBI chr  X:66,018,870...66,018,979
Ensembl chr  X:66,018,870...66,018,979 		JBrowse link
G MIR224 microRNA 224 severity IEP miRNA:increased expression:liver (human)
miRNA:increased expression:plasma (human)
associated with hepatitis B;miRNA:increased expression:liver (human) 		RGD PMID:23922662 PMID:27462777 PMID:24923856 PMID:23913306 PMID:22459148 RGD:18182921, RGD:18182926, RGD:18182924, RGD:18182923, RGD:18182922 NCBI chr  X:151,958,578...151,958,658
Ensembl chr  X:151,958,578...151,958,658 		JBrowse link
G MIR23A microRNA 23a IEP miRNA:increased expression:liver RGD PMID:22318941 RGD:14694846 NCBI chr19:13,836,587...13,836,659
Ensembl chr19:13,836,587...13,836,659 		JBrowse link
G MIR23B microRNA 23b IDA DNA:hypermethylation RGD PMID:28036298 RGD:153344564 NCBI chr 9:95,085,208...95,085,304
Ensembl chr 9:95,085,208...95,085,304 		JBrowse link
G MIR25 microRNA 25 severity IEP miRNA:increased expression:liver (human)
associated with hepatitis B;miRNA:increased expression:liver (human)
associated with hepatitis B;miRNA:increased expression:serum (human) 		RGD PMID:30191950 PMID:27298561 PMID:21098710 PMID:24593846 RGD:15039389, RGD:15042853, RGD:15042899, RGD:15042897 NCBI chr 7:100,093,560...100,093,643
Ensembl chr 7:100,093,560...100,093,643 		JBrowse link
G MIR27A microRNA 27a severity
treatment 		IMP human cell line in a mouse model
human miRNA and cell line in a mouse model 		RGD PMID:29143999 PMID:30083261 RGD:14696659, RGD:14696660 NCBI chr19:13,836,440...13,836,517
Ensembl chr19:13,836,440...13,836,517 		JBrowse link
G MIR29A microRNA 29a severity IEP associated with hepatitis B;miRNA:increased expression:liver (human) RGD PMID:23285022 RGD:15042850 NCBI chr 7:130,876,747...130,876,810
Ensembl chr 7:130,876,747...130,876,810 		JBrowse link
G MIR302D microRNA 302d ameliorates IMP Human cells in mouse model RGD PMID:28352351 RGD:152998975 NCBI chr 4:112,648,004...112,648,071
Ensembl chr 4:112,648,004...112,648,071 		JBrowse link
G MIR31 microRNA 31 severity IEP
ISO 		RNA:decreased expression:liver (human)
miRNA:decreased expression:liver (rat)
miRNA:decreased expression:liver (human) 		RGD PMID:28623129 PMID:25797269 PMID:25797269 RGD:152998991, RGD:11085965, RGD:11085965 NCBI chr 9:21,512,115...21,512,185
Ensembl chr 9:21,512,115...21,512,185 		JBrowse link
G MIR340 microRNA 340 IEP miRNA:decreased expression:liver RGD PMID:27998770 RGD:18936991 NCBI chr 5:180,015,303...180,015,397
Ensembl chr 5:180,015,303...180,015,397 		JBrowse link
G MIR34A microRNA 34a treatment IMP
IEP 		human cell line in a mouse model
miRNA:decreased expression:liver 		RGD PMID:25217526 PMID:29328457 RGD:14694835, RGD:14694836 NCBI chr 1:9,151,668...9,151,777
Ensembl chr 1:9,151,668...9,151,777 		JBrowse link
G MIR3663 microRNA 3663 EXP CTD Direct Evidence: therapeutic CTD PMID:33838155 NCBI chr10:117,167,678...117,167,774
Ensembl chr10:117,167,678...117,167,774 		JBrowse link
G MIR411 microRNA 411 disease_progression IEP mRNA:decreased expression:liver (human) RGD PMID:30086881 RGD:152999437 NCBI chr14:101,023,325...101,023,420
Ensembl chr14:101,023,325...101,023,420 		JBrowse link
G MIR432 microRNA 432 disease_progression IEP
IMP 		mRNA:decreased expression:liver (human)
human cells in mouse model 		RGD PMID:25797263 PMID:30086881 PMID:33675609 PMID:25797263 RGD:11087457, RGD:152999437, RGD:152999436, RGD:11087457 NCBI chr14:100,884,483...100,884,576
Ensembl chr14:100,884,483...100,884,576 		JBrowse link
G MIR455 microRNA 455 EXP CTD Direct Evidence: marker/mechanism CTD PMID:35286011 NCBI chr 9:114,209,434...114,209,529
Ensembl chr 9:114,209,434...114,209,529 		JBrowse link
G MIR494 microRNA 494 disease_progression IEP RGD PMID:25820676 RGD:155900754 NCBI chr14:101,029,634...101,029,714
Ensembl chr14:101,029,634...101,029,714 		JBrowse link
G MIR520B microRNA 520b EXP CTD Direct Evidence: marker/mechanism CTD PMID:29191453 NCBI chr19:53,701,227...53,701,287
Ensembl chr19:53,701,227...53,701,287 		JBrowse link
G MIR539 microRNA 539 EXP CTD Direct Evidence: therapeutic CTD PMID:27717846 NCBI chr14:101,047,321...101,047,398
Ensembl chr14:101,047,321...101,047,398 		JBrowse link
G MIR615 microRNA 615 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22819824 NCBI chr12:54,033,950...54,034,045
Ensembl chr12:54,033,950...54,034,045 		JBrowse link
G MIR637 microRNA 637 EXP CTD Direct Evidence: marker/mechanism CTD PMID:36029209 NCBI chr19:3,961,414...3,961,512
Ensembl chr19:3,961,414...3,961,512 		JBrowse link
G MIR665 microRNA 665 disease_progression IEP
IMP
IGI 		mRNA:increased expression:liver (human)
associated with metastasis; human cells in mouse model 		RGD PMID:30237408 PMID:30237408 PMID:30237408 RGD:151361293, RGD:151361293, RGD:151361293 NCBI chr14:100,875,033...100,875,104
Ensembl chr14:100,875,033...100,875,104 		JBrowse link
G MIR766 microRNA 766 IEP
IMP 		mRNA:decreased expression:liver (human)
human cells in mouse model 		RGD PMID:32048611 PMID:32048611 RGD:153344521, RGD:153344521 NCBI chr  X:119,646,738...119,646,848
Ensembl chr  X:119,646,738...119,646,848 		JBrowse link
G MIR769 microRNA 769 EXP CTD Direct Evidence: marker/mechanism CTD PMID:36029209 NCBI chr19:46,018,932...46,019,049
Ensembl chr19:46,018,932...46,019,049 		JBrowse link
G MIR885 microRNA 885 EXP CTD Direct Evidence: therapeutic CTD PMID:27738331 NCBI chr 3:10,394,489...10,394,562
Ensembl chr 3:10,394,489...10,394,562 		JBrowse link
G MIR93 microRNA 93 severity IEP associated with hepatitis B;miRNA:increased expression:liver (human) RGD PMID:27298561 PMID:28592130 RGD:15042853, RGD:15042900 NCBI chr 7:100,093,768...100,093,847
Ensembl chr 7:100,093,768...100,093,847 		JBrowse link
G MIR940 microRNA 940 IEP RNA:decreased expression:liver (human) RGD PMID:30710422 RGD:153344549 NCBI chr16:2,271,747...2,271,840
Ensembl chr16:2,271,747...2,271,840 		JBrowse link
G MIR96 microRNA 96 severity IEP miRNA:increased expression:liver (human) RGD PMID:28892647 PMID:25813403 RGD:15042901, RGD:15042902 NCBI chr 7:129,774,692...129,774,769
Ensembl chr 7:129,774,692...129,774,769 		JBrowse link
G MIRLET7C microRNA let-7c IEP miRNA:decreased expression:liver RGD PMID:22289550 RGD:14695021 NCBI chr21:16,539,828...16,539,911
Ensembl chr21:16,539,828...16,539,911 		JBrowse link
G MKI67 marker of proliferation Ki-67 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423 		JBrowse link
G MLXIPL MLX interacting protein like EXP CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr 7:73,593,202...73,647,907
Ensembl chr 7:73,593,194...73,624,543 		JBrowse link
G MME membrane metalloendopeptidase ISO RGD PMID:8302012 RGD:13801035 NCBI chr 3:155,024,202...155,183,729
Ensembl chr 3:155,024,124...155,183,704 		JBrowse link
G MMP14 matrix metallopeptidase 14 EXP CTD Direct Evidence: marker/mechanism CTD PMID:33010264 NCBI chr14:22,836,585...22,847,758
Ensembl chr14:22,836,560...22,849,041 		JBrowse link
G MMP2 matrix metallopeptidase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20084675 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO
EXP 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20084675 PMID:21681821 RGD:8547864 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MOGAT2 monoacylglycerol O-acyltransferase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:75,717,838...75,732,953
Ensembl chr11:75,717,838...75,732,958 		JBrowse link
G MPL MPL proto-oncogene, thrombopoietin receptor ISO human cells in mouse model RGD PMID:23157389 RGD:126925755 NCBI chr 1:43,337,818...43,354,466
Ensembl chr 1:43,337,818...43,354,466 		JBrowse link
G MPO myeloperoxidase disease_progression
susceptibility 		EXP
IAGP 		CTD Direct Evidence: marker/mechanism
associated with liver cirrhosis with Hepatitis C;DNA:SNP:promoter:-463G>A(human)
associated with liver cirrhosis; DNA:SNP:promoter:-463G>A( rs2333227)(human) 		CTD
RGD		 PMID:19731237 PMID:21907168 PMID:19731237 RGD:27095879, RGD:26923907 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G MRO maestro EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr18:50,795,130...50,825,380
Ensembl chr18:50,795,120...50,825,402 		JBrowse link
G MSH5 mutS homolog 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:31,740,005...31,762,676
Ensembl chr 6:31,739,677...31,762,676 		JBrowse link
G MT-CO1 mitochondrially encoded cytochrome c oxidase I ISO RGD PMID:2548155 RGD:2302301 NCBI chr MT:5,904...7,445
Ensembl chr MT:5,904...7,445 		JBrowse link
G MT-ND5 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 ISO
EXP 		mRNA:increased expression:liver
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:2507335 PMID:2507335 RGD:2302316 NCBI chr MT:12,337...14,148
Ensembl chr MT:12,337...14,148 		JBrowse link
G MT1A metallothionein 1A EXP CTD Direct Evidence: marker/mechanism CTD PMID:17363595 PMID:19363144 NCBI chr16:56,638,666...56,640,087
Ensembl chr16:56,638,666...56,640,087 		JBrowse link
G MT1E metallothionein 1E EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:56,625,781...56,627,112
Ensembl chr16:56,625,475...56,627,112 		JBrowse link
G MT1F metallothionein 1F EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:56,657,959...56,659,303
Ensembl chr16:56,657,731...56,660,698 		JBrowse link
G MT2A metallothionein 2A EXP CTD Direct Evidence: marker/mechanism CTD PMID:17363595 PMID:28284560 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497 		JBrowse link
G MTBP MDM2 binding protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:29765550 NCBI chr 8:120,445,419...120,523,636
Ensembl chr 8:120,445,400...120,542,133 		JBrowse link
G MTDH metadherin treatment IMP human cells in a mouse model RGD PMID:26351209 RGD:11096879 NCBI chr 8:97,644,184...97,730,260
Ensembl chr 8:97,644,184...97,730,260 		JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase ISO mRNA:increased expression:liver RGD PMID:3878730 RGD:2302305 NCBI chr 2:74,198,615...74,217,565
Ensembl chr 2:74,186,172...74,217,565 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase susceptibility
onset
disease_progression 		IAGP DNA:SNP,haplotype: :677C>T, 1298A>C(human)
DNA:SNPs: :677C>T, 1298A>C(human)
DNA:SNP: :1298A>C(human)
DNA:SNP: :677C>T(human) 		RGD PMID:17503006 PMID:17659576 PMID:19035314 PMID:23996892 RGD:14696703, RGD:14696708, RGD:14696707, RGD:14696704 NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455 		JBrowse link
G MTOR mechanistic target of rapamycin kinase severity EXP
IEP 		CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:liver (human) 		CTD
RGD		 PMID:21147110 PMID:25371154 RGD:152995471 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase susceptibility IAGP DNA:SNP: :66A>G(human) RGD PMID:19035314 RGD:14696707 NCBI chr 5:7,850,859...7,901,113
Ensembl chr 5:7,851,186...7,906,025 		JBrowse link
G MVK mevalonate kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr12:109,573,272...109,598,125
Ensembl chr12:109,573,255...109,598,125 		JBrowse link
G MYBL2 MYB proto-oncogene like 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:43,667,114...43,716,482
Ensembl chr20:43,667,019...43,716,495 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor severity
treatment 		ISO
ISS
EXP
IEP 		OMIM:114550
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver (human)
mRNA:increased expression:liver (rat) 		MouseDO
CTD
RGD		 PMID:9029167 PMID:12029619 PMID:15565109 PMID:29698666 PMID:21644509 More... RGD:6903288, RGD:7241004, RGD:7240695, RGD:7240567 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor exacerbates
treatment
ameliorates 		IEP
IMP
ISO 		mRNA:increased expression:liver (human)
human gene and cell in a mouse model
mouse cell line in a mouse model
protein:increased expression:liver (human)
human cell line in a mouse model
protein, mRNA:decreased expression:liver (human) 		RGD PMID:29022910 PMID:24603331 PMID:31074165 PMID:26985932 PMID:31068809 More... RGD:150520022, RGD:150530285, RGD:150524334, RGD:150524330, RGD:150524329, RGD:150524327, RGD:150521534, RGD:150521532, RGD:150520169 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G NAT2 N-acetyltransferase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:18,386,301...18,401,218
Ensembl chr 8:18,391,282...18,401,218 		JBrowse link
G NBN nibrin IAGP ClinVar Annotator: match by term: Hepatocellular cancer ClinVar PMID:9590180 PMID:9590181 PMID:9620777 PMID:10398434 PMID:10799436 More... NCBI chr 8:89,933,331...89,984,667
Ensembl chr 8:89,924,515...90,003,228 		JBrowse link
G NCAPG non-SMC condensin I complex subunit G EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:17,810,979...17,844,865
Ensembl chr 4:17,810,979...17,844,865 		JBrowse link
G NCAPH non-SMC condensin I complex subunit H EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:96,335,766...96,377,091
Ensembl chr 2:96,335,766...96,377,091 		JBrowse link
G NCOA2 nuclear receptor coactivator 2 exacerbates ISO RGD PMID:28273073 PMID:22556267 RGD:153002573, RGD:153002576 NCBI chr 8:70,109,782...70,456,446
Ensembl chr 8:70,109,782...70,403,808 		JBrowse link
G NDC80 NDC80 kinetochore complex component EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr18:2,571,557...2,616,635
Ensembl chr18:2,571,557...2,616,635 		JBrowse link
G NEIL3 nei like DNA glycosylase 3 disease_progression EXP
IEP 		CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver (human) 		CTD
RGD		 PMID:28284560 PMID:35693827 RGD:153344586 NCBI chr 4:177,309,874...177,371,268
Ensembl chr 4:177,309,874...177,362,936 		JBrowse link
G NEK2 NIMA related kinase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:211,658,256...211,675,621
Ensembl chr 1:211,658,657...211,675,630 		JBrowse link
G NF2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor disease_progression IAGP
IEP 		DNA, protein:SNP, increased expression:intron, liver
protein:decreased expression:liver 		RGD PMID:29130106 PMID:26443326 PMID:27289045 RGD:150530489, RGD:11076529, RGD:150530504 NCBI chr22:29,603,556...29,698,600
Ensembl chr22:29,603,553...29,698,598 		JBrowse link
G NFE2L1 NFE2 like bZIP transcription factor 1 ISS OMIM:114550 MouseDO NCBI chr17:48,048,359...48,061,545
Ensembl chr17:48,048,329...48,061,545 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 EXP
IDA 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:22561517 PMID:31546024 RGD:21201310 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 disease_progression
treatment 		IAGP
ISO 		associated with Chronic Hepatitis B;DNA:insertion/deletion:3'utr: -94ins/delATTG (rs28720239) (human) RGD PMID:19797428 PMID:25999787 RGD:40400751, RGD:152177911 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NFKBIA NFKB inhibitor alpha susceptibility
disease_progression 		EXP
IAGP 		CTD Direct Evidence: therapeutic
associated with hepatitis B;DNA:SNP:promoter:-826C>T (rs2233406) (human)
associated with Chronic Hepatitis B;DNA:SNPs,haplotype:3'utr,promoter: 826C>T,881A>G (rs2233406,rs3138053) (human) 		CTD
RGD		 PMID:22022477 PMID:25223483 PMID:19797428 RGD:40902986, RGD:40400751 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NKILA NF-kappaB interacting lncRNA EXP CTD Direct Evidence: marker/mechanism CTD PMID:29481769 NCBI chr20:57,710,183...57,712,780
Ensembl chr20:57,710,156...57,712,780 		JBrowse link
G NKX3-1 NK3 homeobox 1 treatment IEP
IMP 		mRNA:decreased expression:liver
human gene in a mouse model 		RGD PMID:28972178 PMID:28972178 RGD:14401599, RGD:14401599 NCBI chr 8:23,678,693...23,682,938
Ensembl chr 8:23,678,697...23,682,938 		JBrowse link
G NLRC3 NLR family CARD domain containing 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30081150 NCBI chr16:3,539,033...3,577,403
Ensembl chr16:3,539,033...3,577,403 		JBrowse link
G NLRC5 NLR family CARD domain containing 5 IEP protein:increased expression:liver RGD PMID:27338800 RGD:15003194 NCBI chr16:56,989,557...57,083,520
Ensembl chr16:56,989,485...57,083,531 		JBrowse link
G NME1 NME/NM23 nucleoside diphosphate kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr17:51,153,559...51,162,168
Ensembl chr17:51,153,559...51,162,428 		JBrowse link
G NNMT nicotinamide N-methyltransferase EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:114,257,806...114,313,536
Ensembl chr11:114,257,787...114,313,536 		JBrowse link
G NOS2 nitric oxide synthase 2 treatment ISO RGD PMID:25999787 RGD:152177911 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOTCH3 notch receptor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr19:15,159,038...15,200,995
Ensembl chr19:15,159,038...15,200,995 		JBrowse link
G NR0B2 nuclear receptor subfamily 0 group B member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23811326 NCBI chr 1:26,911,489...26,913,975
Ensembl chr 1:26,911,489...26,913,975 		JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr19:50,376,457...50,383,388
Ensembl chr19:50,329,653...50,383,388 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 EXP
ISS
IMP
IEP
ISO 		CTD Direct Evidence: marker/mechanism
OMIM:114550
intestinally expressed human gene in mouse model
mRNA:splice variant(s):liver (human) 		CTD
MouseDO
RGD		 PMID:23811326 PMID:25496033 PMID:24954587 PMID:23213087 PMID:23811326 RGD:14928334, RGD:14928330, RGD:14696796 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414 		JBrowse link
G NRAS NRAS proto-oncogene, GTPase disease_progression
severity 		IGI
IAGP 		human gene in mouse model
mRNA, protein:increased expression:liver (mouse, human) 		RGD PMID:21993994 PMID:30685691 RGD:14696775, RGD:14696793 NCBI chr 1:114,704,469...114,716,771
Ensembl chr 1:114,704,469...114,716,771 		JBrowse link
G NRG1 neuregulin 1 disease_progression IEP associated with hepatitis C;mRNA:altered expression:liver (human
mRNA:increased expression:liver (human) 		RGD PMID:17393520 PMID:27514687 RGD:39456104, RGD:39456110 NCBI chr 8:31,639,245...32,774,046
Ensembl chr 8:31,639,222...32,855,666 		JBrowse link
G NRP1 neuropilin 1 disease_progression IEP protein:decreased expression:liver RGD PMID:25333267 RGD:126848812 NCBI chr10:33,177,493...33,334,667
Ensembl chr10:33,177,492...33,336,262 		JBrowse link
G NUF2 NUF2 component of NDC80 kinetochore complex disease_progression
treatment 		EXP
IEP 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:28284560 PMID:31933938 PMID:30653265 RGD:28912742, RGD:28867240 NCBI chr 1:163,321,954...163,355,759
Ensembl chr 1:163,266,576...163,355,764 		JBrowse link
G NUSAP1 nucleolar and spindle associated protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:41,332,881...41,381,046
Ensembl chr15:41,320,794...41,381,050 		JBrowse link
G OIT3 oncoprotein induced transcript 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:72,893,739...72,933,036
Ensembl chr10:72,893,584...72,933,036 		JBrowse link
G OLFML2A olfactomedin like 2A EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 9:124,777,133...124,814,882
Ensembl chr 9:124,777,133...124,814,885 		JBrowse link
G OLFML2B olfactomedin like 2B EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:161,983,192...162,023,869
Ensembl chr 1:161,983,192...162,023,869 		JBrowse link
G ORC1 origin recognition complex subunit 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:52,372,829...52,409,503
Ensembl chr 1:52,372,829...52,404,423 		JBrowse link
G OTC ornithine transcarbamylase severity IEP mRNA:altered expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr  X:38,327,684...38,422,928
Ensembl chr  X:38,327,598...38,422,908 		JBrowse link
G PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 disease_progression IEP mRNA,protein:decreased expression:liver: RGD PMID:21569763 RGD:12790589 NCBI chr17:2,593,183...2,685,615
Ensembl chr17:2,593,183...2,685,615 		JBrowse link
G PAMR1 peptidase domain containing associated with muscle regeneration 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:35,431,827...35,530,300
Ensembl chr11:35,431,823...35,530,300 		JBrowse link
G PARK7 Parkinsonism associated deglycase EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18695907 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PBK PDZ binding kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:27,809,624...27,837,817
Ensembl chr 8:27,809,624...27,838,082 		JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19363144 PMID:28284560 NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121 		JBrowse link
G PCLAF PCNA clamp associated factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:64,364,304...64,387,687
Ensembl chr15:64,364,304...64,387,687 		JBrowse link
G PCNA proliferating cell nuclear antigen treatment ISO protein:increased expression:liver: RGD PMID:23219601 PMID:25999787 RGD:10448993, RGD:152177911 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626 		JBrowse link
G PDCD1 programmed cell death 1 disease_progression IAGP
IEP 		associated with hepatitis B;DNA:SNP: : +8669 A>G (human) RGD PMID:27034168 PMID:21912640 RGD:40818257, RGD:41410800 NCBI chr 2:241,849,884...241,858,894
Ensembl chr 2:241,849,884...241,858,894 		JBrowse link
G PDGFB platelet derived growth factor subunit B EXP CTD Direct Evidence: marker/mechanism CTD PMID:20506153 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982 		JBrowse link
G PDGFRL platelet derived growth factor receptor like IAGP
EXP 		ClinVar Annotator: match by term: Hepatocellular carcinoma
CTD Direct Evidence: marker/mechanism 		ClinVar
CTD
OMIM		 PMID:7898930 NCBI chr 8:17,576,433...17,643,144
Ensembl chr 8:17,576,433...17,644,071 		JBrowse link
G PDIA3 protein disulfide isomerase family A member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr15:43,746,438...43,773,278
Ensembl chr15:43,746,394...43,773,279 		JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28003426 NCBI chr 7:95,583,499...95,596,516
Ensembl chr 7:95,583,499...95,596,516 		JBrowse link
G PFAS phosphoribosylformylglycinamidine synthase IEP protein:increased expression:liver RGD PMID:6722784 RGD:5135276 NCBI chr17:8,247,608...8,270,486
Ensembl chr17:8,247,618...8,270,491 		JBrowse link
G PFN2 profilin 2 disease_progression IEP mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr 3:149,964,904...149,970,895
Ensembl chr 3:149,964,904...150,050,788 		JBrowse link
G PGD phosphogluconate dehydrogenase EXP CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr 1:10,399,064...10,420,511
Ensembl chr 1:10,398,592...10,420,511 		JBrowse link
G PGK1 phosphoglycerate kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr  X:78,104,248...78,129,295
Ensembl chr  X:77,910,739...78,129,295 		JBrowse link
G PHB1 prohibitin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr17:49,404,052...49,414,882
Ensembl chr17:49,404,049...49,414,905 		JBrowse link
G PHF6 PHD finger protein 6 exacerbates IEP mRNA:increased expression:liver (human) RGD PMID:31329335 PMID:30888215 RGD:155260288, RGD:155260308 NCBI chr  X:134,373,312...134,428,790
Ensembl chr  X:134,373,288...134,428,791 		JBrowse link
G PHLDA1 pleckstrin homology like domain family A member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:76,025,447...76,031,776
Ensembl chr12:76,025,447...76,031,776 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha treatment
susceptibility
no_association
severity 		TAS
IAGP
EXP
ISO 		ClinVar Annotator: match by term: Hepatocellular cancer
ClinVar Annotator: match by term: Hepatocellular carcinoma
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :rs17849071,rs17849079(human)
DNA:mutation:exon:
DNA:mutations:exons: 		ClinVar
CTD
OMIM
RGD		 PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... RGD:2290476, RGD:152177911, RGD:11556371, RGD:14402405, RGD:14402404 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093 		JBrowse link
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta treatment ISO RGD PMID:25999787 RGD:152177911 NCBI chr 3:138,652,698...138,834,928
Ensembl chr 3:138,652,336...138,834,928 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 treatment ISO RGD PMID:31801250 PMID:25999787 RGD:151893509, RGD:152177911 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821 		JBrowse link
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 treatment ISO RGD PMID:25999787 RGD:152177911 NCBI chr19:18,153,163...18,170,532
Ensembl chr19:18,153,163...18,170,540 		JBrowse link
G PIK3R3 phosphoinositide-3-kinase regulatory subunit 3 treatment ISO RGD PMID:25999787 RGD:152177911 NCBI chr 1:46,040,140...46,174,901
Ensembl chr 1:46,040,140...46,133,036 		JBrowse link
G PINX1 PIN2 (TERF1) interacting telomerase inhibitor 1 disease_progression IAGP associated with Chronic Hepatitis B; DNA:SNP::rs1469557(human) RGD PMID:27221889 RGD:152977752 NCBI chr 8:10,764,961...10,839,875
Ensembl chr 8:10,725,399...10,839,847
Ensembl chr 8:10,725,399...10,839,847 		JBrowse link
G PITPNM3 PITPNM family member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:6,451,263...6,556,555
Ensembl chr17:6,451,263...6,556,555 		JBrowse link
G PITX1 paired like homeodomain 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:135,027,734...135,034,789
Ensembl chr 5:135,027,734...135,034,813 		JBrowse link
G PKM pyruvate kinase M1/2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr15:72,199,029...72,231,591
Ensembl chr15:72,199,029...72,231,819 		JBrowse link
G PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:2,972,808...2,980,446
Ensembl chr16:2,968,024...2,980,479 		JBrowse link
G PKP1 plakophilin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 1:201,283,506...201,332,989
Ensembl chr 1:201,283,452...201,332,993 		JBrowse link
G PLAC8 placenta associated 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:83,090,048...83,114,729
Ensembl chr 4:83,059,493...83,137,075 		JBrowse link
G PLAU plasminogen activator, urokinase ISS OMIM:114550 MouseDO NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496 		JBrowse link
G PLCG1 phospholipase C gamma 1 ameliorates IMP human cell line in a mouse model RGD PMID:30623526 RGD:151356937 NCBI chr20:41,137,543...41,177,626
Ensembl chr20:41,136,960...41,196,801 		JBrowse link
G PLK1 polo like kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:23,678,889...23,690,367
Ensembl chr16:23,677,656...23,690,367 		JBrowse link
G PLK4 polo like kinase 4 sexual_dimorphism ISO
IEP 		DNA:hypermethylation:promoter RGD PMID:21324136 PMID:21324136 RGD:27226690, RGD:27226690 NCBI chr 4:127,880,893...127,899,224
Ensembl chr 4:127,880,893...127,899,224 		JBrowse link
G PLOD3 procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 treatment IEP
ISO 		mRNA, protein:increased expression:liver (human) RGD PMID:29059470 PMID:29059470 RGD:155791679, RGD:155791679 NCBI chr 7:101,205,984...101,217,581
Ensembl chr 7:101,205,977...101,218,420 		JBrowse link
G PLVAP plasmalemma vesicle associated protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr19:17,351,455...17,377,342
Ensembl chr19:17,351,450...17,377,342 		JBrowse link
G PLXDC1 plexin domain containing 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:39,063,313...39,152,967
Ensembl chr17:39,063,313...39,154,394 		JBrowse link
G PML PML nuclear body scaffold disease_progression
ameliorates
exacerbates 		IEP
ISO 		protein:increased expression:liver (human)
mRNA:increased expression:liver (mouse)
associated with hepatitis C 		RGD PMID:11511788 PMID:26118777 PMID:31144474 RGD:41404685, RGD:41404690, RGD:41404687 NCBI chr15:73,994,716...74,047,827
Ensembl chr15:73,994,673...74,047,827 		JBrowse link
G PMS2 PMS1 homolog 2, mismatch repair system component IAGP ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar NCBI chr 7:5,970,925...6,009,106
Ensembl chr 7:5,970,925...6,009,130 		JBrowse link
G PNPLA3 patatin like phospholipase domain containing 3 IAGP associated with Hepatitis C, Chronic;DNA:SNP: :rs738409 (p.I148M) (human) RGD PMID:21319195 RGD:14981585 NCBI chr22:43,923,805...43,947,582
Ensembl chr22:43,923,792...43,964,488 		JBrowse link
G PNPT1 polyribonucleotide nucleotidyltransferase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 2:55,634,061...55,693,844
Ensembl chr 2:55,634,061...55,693,863 		JBrowse link
G POLG DNA polymerase gamma, catalytic subunit susceptibility IAGP DNA:SNPs:introns: (rs1061316, rs758130) (human) RGD PMID:28457473 RGD:15039387 NCBI chr15:89,316,320...89,334,824
Ensembl chr15:89,305,198...89,334,861 		JBrowse link
G PON1 paraoxonase 1 disease_progression IEP mRNA:decreased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532 		JBrowse link
G POT1 protection of telomeres 1 disease_progression IAGP associated with hepatitis B;DNA:SNP: :rs7784168(human) RGD PMID:23907815 RGD:152975963 NCBI chr 7:124,822,386...124,929,825
Ensembl chr 7:124,822,386...124,929,983 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha susceptibility IAGP associated with hepatitis B;DNA:missense mutation:cds:p.L162V (human) RGD PMID:19119483 RGD:15042881 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma severity EXP
IEP 		CTD Direct Evidence: therapeutic
protein:decreased expression:liver 		CTD
RGD		 PMID:16374840 PMID:27451128 RGD:14694822 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PPAT phosphoribosyl pyrophosphate amidotransferase ISO protein:increased activity:hepatoma (rat) RGD PMID:6327016 RGD:5135035 NCBI chr 4:56,393,362...56,435,615
Ensembl chr 4:56,393,362...56,435,615 		JBrowse link
G PPP1R1A protein phosphatase 1 regulatory inhibitor subunit 1A EXP CTD Direct Evidence: marker/mechanism CTD PMID:15010824 NCBI chr12:54,579,246...54,588,659
Ensembl chr12:54,575,387...54,588,659 		JBrowse link
G PPP1R9A protein phosphatase 1 regulatory subunit 9A onset ISO protein:increased expression:liver (rat) RGD PMID:20935162 RGD:10002734 NCBI chr 7:94,907,236...95,296,415
Ensembl chr 7:94,907,202...95,296,415 		JBrowse link
G PPP1R9B protein phosphatase 1 regulatory subunit 9B severity IEP mRNA, protein:decreased expression:liver (human) RGD PMID:23591196 RGD:10043803 NCBI chr17:50,133,737...50,150,677
Ensembl chr17:50,133,737...50,150,677 		JBrowse link
G PPP4R3C protein phosphatase 4 regulatory subunit 3C EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:27,460,207...27,463,341
Ensembl chr  X:27,460,207...27,463,341 		JBrowse link
G PRC1 protein regulator of cytokinesis 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:90,966,040...90,994,535
Ensembl chr15:90,966,040...90,995,629 		JBrowse link
G PRDM1 PR/SET domain 1 disease_progression IEP
IAGP 		associated with hepatitis B;
associated with hepatitis B;DNA:SNP: :rs1010273(human) 		RGD PMID:31100710 PMID:31376415 RGD:150530465, RGD:150530466 NCBI chr 6:105,992,690...106,109,938
Ensembl chr 6:105,993,463...106,109,939 		JBrowse link
G PRDX1 peroxiredoxin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27517622 NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,510,914...45,542,732 		JBrowse link
G PRDX2 peroxiredoxin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr19:12,796,823...12,801,800
Ensembl chr19:12,796,820...12,801,800 		JBrowse link
G PRDX6 peroxiredoxin 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 1:173,477,335...173,488,815
Ensembl chr 1:173,477,330...173,488,815 		JBrowse link
G PREX2 phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 exacerbates IEP mRNA:increased expression:liver (human)
mRNA:decreased expression:liver (human)
protein:increased expression:liver (human) 		RGD PMID:25151370 PMID:31776854 PMID:28000796 PMID:28205209 RGD:151665185, RGD:151665343, RGD:151665188, RGD:151665186 NCBI chr 8:67,952,046...68,237,032
Ensembl chr 8:67,952,046...68,237,032 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase severity ISO protein:decreased expression:liver (human) RGD PMID:28862485 RGD:13432206 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775 		JBrowse link
G PRL prolactin onset IEP protein:increased expression:serum (human) RGD PMID:22392353 RGD:125097525 NCBI chr 6:22,287,246...22,302,835
Ensembl chr 6:22,287,244...22,302,826 		JBrowse link
G PROM1 prominin 1 ISO mRNA:increased expression:liver (mouse) RGD PMID:26569409 RGD:11344640 NCBI chr 4:15,968,228...16,084,023
Ensembl chr 4:15,963,076...16,084,378 		JBrowse link
G PTCH1 patched 1 severity
disease_progression 		IEP RGD PMID:18538319 PMID:22911366 RGD:150523837, RGD:150523842 NCBI chr 9:95,442,980...95,516,971
Ensembl chr 9:95,442,980...95,517,057 		JBrowse link
G PTEN phosphatase and tensin homolog severity
treatment
exacerbates 		EXP
ISS
IEP
ISO 		CTD Direct Evidence: marker/mechanism
OMIM:114550
protein:decreased expression:liver (human)
associated with hepatitis C, liver cirrhosis;protein:decreased expression:liver (human)
associated with hepatitis B;protein:decreased expression:liver (human) 		CTD
MouseDO
RGD		 PMID:27022031 PMID:29303510 PMID:29303510 PMID:31801250 PMID:12115563 More... RGD:152995524, RGD:152995524, RGD:151893509, RGD:127285610, RGD:127285603, RGD:127285591 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 treatment
severity
susceptibility 		ISO
IEP
IAGP
EXP 		protein:increased expression:liver, cytosol
mRNA,protein:decreased expression:liver
DNA:SNP:promoter:-1195A>G (rs689466) (human)
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:11872629 PMID:12024111 PMID:14563831 PMID:16374840 PMID:17510421 More... RGD:2300283, RGD:152177911, RGD:14695012, RGD:14695011, RGD:14695010 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTH1R parathyroid hormone 1 receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:46,877,721...46,903,799
Ensembl chr 3:46,877,721...46,903,799 		JBrowse link
G PTK2 protein tyrosine kinase 2 ISO
EXP 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:14578863 PMID:17203219 RGD:2292584 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216 		JBrowse link
G PTPN13 protein tyrosine phosphatase non-receptor type 13 disease_progression
susceptibility 		HEP
IAGP 		DNA:SNP: :p.Y2081D(human) RGD PMID:26801674 PMID:16489062 RGD:152176666, RGD:152599190 NCBI chr 4:86,594,315...86,815,161
Ensembl chr 4:86,594,315...86,815,171 		JBrowse link
G PTPRB protein tyrosine phosphatase receptor type B disease_progression IEP mRNA:decreased expression:liver (human) RGD PMID:30237408 RGD:151361293 NCBI chr12:70,515,870...70,637,429
Ensembl chr12:70,515,870...70,637,440 		JBrowse link
G PTTG1 PTTG1 regulator of sister chromatid separation, securin EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:160,421,855...160,428,744
Ensembl chr 5:160,421,855...160,428,739 		JBrowse link
G PVT1 Pvt1 oncogene IEP
IGI
IMP 		mRNA:increased expression:liver (human)
human cells in mouse model 		RGD PMID:30205391 PMID:30205391 PMID:30205391 RGD:153344577, RGD:153344577, RGD:153344577 NCBI chr 8:127,794,524...128,101,256
Ensembl chr 8:127,794,513...128,188,202 		JBrowse link
G PYCARD PYD and CARD domain containing EXP CTD Direct Evidence: marker/mechanism CTD PMID:17471463 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450 		JBrowse link
G PYGL glycogen phosphorylase L EXP CTD Direct Evidence: marker/mechanism CTD PMID:2885971 NCBI chr14:50,905,217...50,944,483
Ensembl chr14:50,857,891...50,944,483 		JBrowse link
G PZP PZP alpha-2-macroglobulin like EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:9,136,472...9,208,395
Ensembl chr12:9,148,840...9,208,395 		JBrowse link
G RAC1 Rac family small GTPase 1 exacerbates EXP
IEP
HEP 		CTD Direct Evidence: marker/mechanism
protein:increased expression:liver (human)
mRNA:increased expression:liver (human) 		CTD
RGD		 PMID:18506888 PMID:20522449 PMID:33482578 RGD:153350129, RGD:153298967 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967 		JBrowse link
G RACGAP1 Rac GTPase activating protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:49,989,162...50,033,440
Ensembl chr12:49,976,923...50,033,136 		JBrowse link
G RAD21 RAD21 cohesin complex component treatment
exacerbates
susceptibility 		IMP
IEP
HEP 		human cells in a mouse model
mRNA:increased expression:liver (human)
protein:increased expression:liver (human)
associated with hepatitis c, liver cirrhosis;mRNA:increased expression:liver (human) 		RGD PMID:33251678 PMID:32596342 PMID:28434945 PMID:30698808 RGD:150520026, RGD:150520035, RGD:150520030, RGD:150520029 NCBI chr 8:116,845,934...116,874,776
Ensembl chr 8:116,845,934...116,874,776 		JBrowse link
G RAD50 RAD50 double strand break repair protein IAGP ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar PMID:16385572 PMID:18281469 PMID:19409520 PMID:24894818 PMID:25452441 More... NCBI chr 5:132,556,977...132,646,349
Ensembl chr 5:132,556,019...132,646,349 		JBrowse link
G RAD52 RAD52 homolog, DNA repair protein susceptibility
onset 		IAGP
IEP 		associated with hepatitis B;DNA:SNP:3'utr: (rs7963551) (human)
mRNA,protein:increased expression:liver (human) 		RGD PMID:24729511 PMID:31719794 RGD:151361199, RGD:151361207 NCBI chr12:911,736...991,122
Ensembl chr12:911,736...990,053 		JBrowse link
G RAD54L RAD54 like EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:46,247,688...46,278,473
Ensembl chr 1:46,246,461...46,278,480 		JBrowse link
G RARA retinoic acid receptor alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:18026104 NCBI chr17:40,309,180...40,357,643
Ensembl chr17:40,309,180...40,357,643 		JBrowse link
G RB1 RB transcriptional corepressor 1 treatment EXP
ISO 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:12029619 PMID:14961299 PMID:33841550 RGD:152998960 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436 		JBrowse link
G RBM10 RNA binding motif protein 10 disease_progression IEP mRNA:decreased expression:liver RGD PMID:32572914 RGD:151356975 NCBI chr  X:47,145,221...47,186,813
Ensembl chr  X:47,145,221...47,186,813 		JBrowse link
G RCAN1 regulator of calcineurin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr21:34,516,442...34,615,113
Ensembl chr21:34,513,142...34,615,113 		JBrowse link
G RECQL RecQ like helicase disease_progression IMP
IEP 		protein:increased expression:liver RGD PMID:18422747 PMID:18422747 RGD:2317370, RGD:2317370 NCBI chr12:21,468,910...21,501,635
Ensembl chr12:21,468,910...21,501,669 		JBrowse link
G REG3A regenerating family member 3 alpha IEP mRNA:increased expression:liver (human) RGD PMID:10550309 RGD:9831380 NCBI chr 2:79,157,006...79,159,753
Ensembl chr 2:79,157,003...79,159,753 		JBrowse link
G RET ret proto-oncogene severity HEP
IAGP 		protein:increased expression:liver (human)
ClinVar Annotator: match by term: Hepatocellular carcinoma 		ClinVar
RGD		 PMID:7784092 PMID:7845675 PMID:7911697 PMID:8807338 PMID:8918855 More... RGD:150340602 NCBI chr10:43,077,069...43,130,351
Ensembl chr10:43,077,064...43,130,351 		JBrowse link
G RGN regucalcin ISO protein:decreased expression:liver RGD PMID:21683810 RGD:5509919 NCBI chr  X:47,078,443...47,093,313
Ensembl chr  X:47,078,355...47,093,314 		JBrowse link
G RICTOR RPTOR independent companion of MTOR complex 2 severity IEP
ISO 		mRNA, protein:increased expression:liver (human) RGD PMID:25371154 PMID:29303510 RGD:152995471, RGD:152995524 NCBI chr 5:38,937,920...39,074,399
Ensembl chr 5:38,937,920...39,074,402 		JBrowse link
G RIT1 Ras like without CAAX 1 ameliorates IMP human cells in mouse model RGD PMID:31247273 RGD:152999016 NCBI chr 1:155,897,808...155,911,349
Ensembl chr 1:155,897,808...155,911,404 		JBrowse link
G RND3 Rho family GTPase 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:150,468,193...150,487,695
Ensembl chr 2:150,468,195...150,539,011 		JBrowse link
G RNF157 ring finger protein 157 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:76,142,474...76,240,493
Ensembl chr17:76,142,465...76,240,493 		JBrowse link
G RNF43 ring finger protein 43 exacerbates IMP human cells in a mouse model RGD PMID:23136185 RGD:151361219 NCBI chr17:58,352,500...58,417,534
Ensembl chr17:58,353,676...58,417,595 		JBrowse link
G RNF6 ring finger protein 6 disease_progression IEP RGD PMID:30496760 RGD:151665757 NCBI chr13:26,132,115...26,223,085
Ensembl chr13:26,132,115...26,222,314 		JBrowse link
G ROBO1 roundabout guidance receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:78,597,239...79,767,998
Ensembl chr 3:78,597,239...79,767,998 		JBrowse link
G RPS6 ribosomal protein S6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr 9:19,375,715...19,380,236
Ensembl chr 9:19,375,715...19,380,236 		JBrowse link
G RPS6KA3 ribosomal protein S6 kinase A3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22561517 NCBI chr  X:20,149,911...20,267,097
Ensembl chr  X:20,149,911...20,267,519 		JBrowse link
G RRM1 ribonucleotide reductase catalytic subunit M1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18230555 NCBI chr11:4,094,685...4,138,932
Ensembl chr11:4,094,707...4,138,932 		JBrowse link
G RRM2 ribonucleotide reductase regulatory subunit M2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18230555 PMID:28284560 NCBI chr 2:10,122,568...10,211,010
Ensembl chr 2:10,120,698...10,211,725 		JBrowse link
G RSPO3 R-spondin 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:127,118,671...127,199,481
Ensembl chr 6:127,118,671...127,199,481 		JBrowse link
G RTKN rhotekin IEP mRNA:increased expression:liver RGD PMID:27922690 RGD:19165144 NCBI chr 2:74,425,835...74,441,937
Ensembl chr 2:74,425,835...74,442,422 		JBrowse link
G RTP3 receptor transporter protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17693185 NCBI chr 3:46,497,976...46,500,950
Ensembl chr 3:46,494,611...46,500,950 		JBrowse link
G RUNX1 RUNX family transcription factor 1 IEP mRNA:decreased expression:liver RGD PMID:17094378 RGD:126775147 NCBI chr21:34,787,801...35,049,302
Ensembl chr21:34,787,801...36,004,667 		JBrowse link
G RUNX3 RUNX family transcription factor 3 EXP
IEP 		CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:liver 		CTD
RGD		 PMID:28458013 PMID:17094378 RGD:126775147 NCBI chr 1:24,899,511...24,965,138
Ensembl chr 1:24,899,511...24,965,121 		JBrowse link
G RYR3 ryanodine receptor 3 disease_progression IAGP DNA:SNP:3'UTR:rs1044129(human) RGD PMID:26309413 RGD:155882454 NCBI chr15:33,310,967...33,866,102
Ensembl chr15:33,310,962...33,866,121 		JBrowse link
G S100A9 S100 calcium binding protein A9 disease_progression IEP mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr 1:153,357,854...153,361,023
Ensembl chr 1:153,357,854...153,361,023 		JBrowse link
G SARDH sarcosine dehydrogenase severity IEP mRNA:altered expression:liver tumor (human) RGD PMID:30901224 RGD:152995286 NCBI chr 9:133,659,418...133,739,955
Ensembl chr 9:133,663,560...133,739,955 		JBrowse link
G SAV1 salvador family WW domain containing protein 1 ISS OMIM:114550 MouseDO NCBI chr14:50,633,580...50,668,306
Ensembl chr14:50,632,058...50,668,306 		JBrowse link
G SCAP SREBF chaperone EXP CTD Direct Evidence: marker/mechanism CTD PMID:14563831 NCBI chr 3:47,413,681...47,477,127
Ensembl chr 3:47,413,681...47,477,126 		JBrowse link
G SCD stearoyl-CoA desaturase EXP CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr10:100,347,233...100,364,826
Ensembl chr10:100,347,233...100,364,826 		JBrowse link
G SERPINA1 serpin family A member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:6258829 PMID:21472284 NCBI chr14:94,376,747...94,390,635
Ensembl chr14:94,376,747...94,390,693 		JBrowse link
G SERPINA4 serpin family A member 4 EXP CTD Direct Evidence: therapeutic CTD PMID:19709125 NCBI chr14:94,561,442...94,569,906
Ensembl chr14:94,561,442...94,569,913 		JBrowse link
G SERPINB5 serpin family B member 5 disease_progression IEP associated with hepatitis B; RGD PMID:26296971 RGD:11520929 NCBI chr18:63,476,958...63,505,085
Ensembl chr18:63,476,958...63,505,085 		JBrowse link
G SERPINF1 serpin family F member 1 IEP associated with Human Viral Hepatitis, liver cirrhosis;protein:increased expression:serum (human) RGD PMID:27748324 RGD:27226704 NCBI chr17:1,762,060...1,777,565
Ensembl chr17:1,762,029...1,777,565 		JBrowse link
G SET SET nuclear proto-oncogene IAGP ClinVar Annotator: match by term: Hepatocellular carcinoma ClinVar PMID:26822237 NCBI chr 9:128,683,424...128,696,396
Ensembl chr 9:128,683,424...128,696,400 		JBrowse link
G SF3B1 splicing factor 3b subunit 1 treatment
disease_progression 		ISO
IMP
IEP
IDA 		protein:increased expression:liver
mRNA, protein:increased expression:liver 		RGD PMID:29954402 PMID:33038489 PMID:33038489 PMID:29954402 RGD:126790493, RGD:126790494, RGD:126790494, RGD:126790493 NCBI chr 2:197,389,784...197,435,093
Ensembl chr 2:197,388,515...197,435,079 		JBrowse link
G SF3B4 splicing factor 3b subunit 4 severity
treatment 		ISO
IEP
IMP 		mRNA, protein:increased expression:liver (rat)
mRNA, protein:increased expression:liver(human)
human cells in mouse model
mRNA, protein:increased expression:liver (human) 		RGD PMID:29059470 PMID:30391496 PMID:30391496 PMID:29059470 PMID:29059470 RGD:155791679, RGD:155804298, RGD:155804298, RGD:155791679, RGD:155791679 NCBI chr 1:149,923,317...149,927,803
Ensembl chr 1:149,923,317...149,927,803 		JBrowse link
G SFN stratifin EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 1:26,863,149...26,864,456
Ensembl chr 1:26,863,149...26,864,456 		JBrowse link
G SFRP1 secreted frizzled related protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:41,261,962...41,309,473
Ensembl chr 8:41,261,962...41,309,473 		JBrowse link
G SH3GL1 SH3 domain containing GRB2 like 1, endophilin A2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:33838155 NCBI chr19:4,360,370...4,400,547
Ensembl chr19:4,360,370...4,400,547 		JBrowse link
G SHC1 SHC adaptor protein 1 ISO protein:increased expression, increased phosphorylation:hepatocyte RGD PMID:15375560 RGD:1643188 NCBI chr 1:154,962,298...154,974,376
Ensembl chr 1:154,962,298...154,974,395 		JBrowse link
G SHH sonic hedgehog signaling molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:26189965 NCBI chr 7:155,799,980...155,812,463
Ensembl chr 7:155,799,980...155,812,463 		JBrowse link
G SIK2 salt inducible kinase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34491613 NCBI chr11:111,602,449...111,730,855
Ensembl chr11:111,602,449...111,730,855 		JBrowse link
G SIX1 SIX homeobox 1 severity IEP protein:increased expression:liver (human) RGD PMID:17008870 RGD:11561961 NCBI chr14:60,643,421...60,649,477
Ensembl chr14:60,643,421...60,658,259 		JBrowse link
G SKA1 spindle and kinetochore associated complex subunit 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr18:50,375,046...50,394,168
Ensembl chr18:50,375,040...50,394,168 		JBrowse link
G SKA3 spindle and kinetochore associated complex subunit 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:21,153,595...21,176,552
Ensembl chr13:21,153,595...21,176,552 		JBrowse link
G SKP2 S-phase kinase associated protein 2 ISO
EXP 		protein:increased expression:liver
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:12717389 PMID:19533683 RGD:2315050 NCBI chr 5:36,152,111...36,193,530
Ensembl chr 5:36,151,989...36,196,849 		JBrowse link
G SLC22A1 solute carrier family 22 member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:160,121,815...160,158,718
Ensembl chr 6:160,121,815...160,158,718 		JBrowse link
G SLC22A10 solute carrier family 22 member 10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 PMID:30705370 NCBI chr11:63,289,903...63,363,144
Ensembl chr11:63,268,022...63,311,783 		JBrowse link
G SLC25A47 solute carrier family 25 member 47 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr14:100,323,339...100,330,421
Ensembl chr14:100,323,339...100,330,421 		JBrowse link
G SLC26A6 solute carrier family 26 member 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:48,625,723...48,635,461
Ensembl chr 3:48,625,723...48,635,493 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:8364915 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893 		JBrowse link
G SLC2A2 solute carrier family 2 member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:8364915 NCBI chr 3:170,996,347...171,026,720
Ensembl chr 3:170,996,347...171,026,743 		JBrowse link
G SLC38A1 solute carrier family 38 member 1 ameliorates
disease_progression 		IMP
IEP 		RGD PMID:26389641 PMID:26389641 RGD:151361140, RGD:151361140 NCBI chr12:46,183,063...46,269,043
Ensembl chr12:46,183,063...46,270,017 		JBrowse link
G SLC5A5 solute carrier family 5 member 5 EXP CTD Direct Evidence: therapeutic CTD PMID:15347726 PMID:15520214 NCBI chr19:17,871,945...17,895,174
Ensembl chr19:17,871,945...17,895,174 		JBrowse link
G SLC7A5 solute carrier family 7 member 5 ameliorates
disease_progression 		IMP
ISO
IEP 		mRNA:increased expression:liver RGD PMID:26389641 PMID:7532544 PMID:23696029 PMID:26389641 RGD:151361140, RGD:634202, RGD:151361280, RGD:151361140 NCBI chr16:87,830,023...87,869,507
Ensembl chr16:87,830,016...87,869,507 		JBrowse link
G SLCO1B3 solute carrier organic anion transporter family member 1B3 disease_progression
exacerbates 		IEP protein:decreased expression:liver (human)
mRNA,protein:decreased expression:liver (human) 		RGD PMID:21626360 PMID:32534581 RGD:152995417, RGD:152995423 NCBI chr12:20,810,705...20,916,911
Ensembl chr12:20,810,702...20,916,911 		JBrowse link
G SLIT2 slit guidance ligand 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19100240 NCBI chr 4:20,251,905...20,620,561
Ensembl chr 4:20,251,905...20,620,561 		JBrowse link
G SMAD2 SMAD family member 2 ISO RGD PMID:18971187 RGD:12880056 NCBI chr18:47,808,957...47,930,872
Ensembl chr18:47,808,957...47,931,146 		JBrowse link
G SMAD4 SMAD family member 4 disease_progression ISO
IEP 		protein:increased expression:liver:
protein:decreased expression:liver 		RGD PMID:18971187 PMID:29924446 PMID:22799322 PMID:23922662 RGD:12880056, RGD:21066342, RGD:21066341, RGD:18182921 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,528...51,085,045 		JBrowse link
G SMAD7 SMAD family member 7 IEP mRNA:increased expression:liver (human) RGD PMID:25602745 RGD:14401589 NCBI chr18:48,919,853...48,950,965
Ensembl chr18:48,919,853...48,950,965 		JBrowse link
G SMARCA4 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4 IAGP DNA:SNPs: :rs11879293, rs2072382 (human) RGD PMID:24556940 RGD:127285650 NCBI chr19:10,961,030...11,062,273
Ensembl chr19:10,960,932...11,079,426 		JBrowse link
G SMARCB1 SWI/SNF related BAF chromatin remodeling complex subunit B1 disease_progression IEP mRNA:decreased expression:liver RGD PMID:27111394 RGD:127285647 NCBI chr22:23,786,966...23,838,009
Ensembl chr22:23,786,931...23,838,009 		JBrowse link
G SMARCC1 SWI/SNF related BAF chromatin remodeling complex subunit C1 ameliorates IEP mRNA, protein:increased expression:liver (human) RGD PMID:32514535 RGD:151347860 NCBI chr 3:47,585,269...47,781,893
Ensembl chr 3:47,585,269...47,782,106 		JBrowse link
G SMC3 structural maintenance of chromosomes 3 exacerbates IMP mRNA:increased editing:cds:p.K96R,p.Q103R(human) RGD PMID:29996118 RGD:156430111 NCBI chr10:110,567,695...110,606,048
Ensembl chr10:110,567,684...110,606,048 		JBrowse link
G SMG9 SMG9 nonsense mediated mRNA decay factor severity IEP RGD PMID:34456727 RGD:155882446 NCBI chr19:43,727,983...43,754,962
Ensembl chr19:43,727,983...43,754,962 		JBrowse link
G SMO smoothened, frizzled class receptor disease_progression IAGP DNA:SNP: :rs3824 (human) RGD PMID:25944162 RGD:150340548 NCBI chr 7:129,188,633...129,213,545
Ensembl chr 7:129,188,633...129,213,545 		JBrowse link
G SNAI1 snail family transcriptional repressor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:35841383 NCBI chr20:49,982,980...49,988,886
Ensembl chr20:49,982,980...49,988,886 		JBrowse link
G SNRPE small nuclear ribonucleoprotein polypeptide E IMP human gene in a mouse model RGD PMID:21688285 RGD:10768833 NCBI chr 1:203,861,599...203,871,152
Ensembl chr 1:203,861,599...203,871,152 		JBrowse link
G SNW1 SNW domain containing 1 severity IEP protein:increased expression:liver (human) RGD PMID:23696020 RGD:11035253 NCBI chr14:77,717,599...77,761,156
Ensembl chr14:77,717,599...77,761,207 		JBrowse link
G SNX27 sorting nexin 27 EXP CTD Direct Evidence: marker/mechanism CTD PMID:36029209 NCBI chr 1:151,612,050...151,699,080
Ensembl chr 1:151,612,006...151,699,091 		JBrowse link
G SOAT1 sterol O-acyltransferase 1 exacerbates HEP associated with hepatitis B;protein:increased expression:liver (human) RGD PMID:30814741 RGD:126925204 NCBI chr 1:179,293,797...179,358,680
Ensembl chr 1:179,293,714...179,358,680 		JBrowse link
G SOAT2 sterol O-acyltransferase 2 IDA RGD PMID:16274362 RGD:1581190 NCBI chr12:53,103,486...53,124,535
Ensembl chr12:53,103,486...53,124,535 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 treatment IDA
ISO 		associated with liver cirrhosis;DNA:altered methylation:liver:
DNA:hypermethylation:CpG island, 5'untranslated region: 		RGD PMID:14614012 PMID:22318090 PMID:15235874 PMID:18843197 RGD:150573687, RGD:150573703, RGD:150573700, RGD:150573689 NCBI chr16:11,254,417...11,256,204
Ensembl chr16:11,254,417...11,256,204 		JBrowse link
G SOCS2 suppressor of cytokine signaling 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:93,569,969...93,626,236
Ensembl chr12:93,569,814...93,583,487 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16831601 NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077 		JBrowse link
G SOD1 superoxide dismutase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:33010264 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SOD2 superoxide dismutase 2 disease_progression
susceptibility 		IDA
EXP
IEP
IAGP 		CTD Direct Evidence: marker/mechanism
protein:increased expression:saliva
associated with liver cirrhosis; DNA:SNP:cds:p.Ala16Val(rs1799725)(human) 		CTD
RGD		 PMID:16767786 PMID:18760346 PMID:19731237 PMID:21472284 PMID:33010264 More... RGD:1581242, RGD:27095881, RGD:26923955, RGD:26923907 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SOX30 SRY-box transcription factor 30 disease_progression
exacerbates 		IEP
IDA 		RGD PMID:30312695 PMID:30312695 RGD:151660341, RGD:151660341 NCBI chr 5:157,625,679...157,671,480
Ensembl chr 5:157,625,679...157,671,480 		JBrowse link
G SPAG9 sperm associated antigen 9 IDA associated with Human Viral Hepatitis RGD PMID:29344208 RGD:30296654 NCBI chr17:50,962,174...51,120,868
Ensembl chr17:50,962,174...51,120,868 		JBrowse link
G SPC25 SPC25 component of NDC80 kinetochore complex EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 2:168,861,521...168,890,430
Ensembl chr 2:168,834,132...168,913,371 		JBrowse link
G SPOCK1 SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 ameliorates IDA human cells in mouse model RGD PMID:30710422 RGD:153344549 NCBI chr 5:136,975,298...137,499,326
Ensembl chr 5:136,975,298...137,598,379 		JBrowse link
G SPOP speckle type BTB/POZ protein exacerbates IEP
IMP 		mRNA:decreased expression:liver (human)
human cells in mouse model 		RGD PMID:26156804 PMID:33209975 RGD:11074965, RGD:153298924 NCBI chr17:49,598,884...49,678,163
Ensembl chr17:49,598,884...49,678,163 		JBrowse link
G SPP1 secreted phosphoprotein 1 disease_progression IDA
IEP 		mRNA:increased expression:liver (human) RGD PMID:16047475 PMID:35693827 RGD:1581375, RGD:153344586 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532 		JBrowse link
G SPRTN SprT-like N-terminal domain EXP CTD Direct Evidence: marker/mechanism CTD PMID:25261934 NCBI chr 1:231,338,293...231,355,023
Ensembl chr 1:231,337,104...231,355,023 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase disease_progression IEP
ISO 		RGD PMID:9581679 PMID:9581679 RGD:150521543, RGD:150521543 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:14563831 PMID:21147110 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr22:41,833,105...41,907,305
Ensembl chr22:41,833,105...41,907,306 		JBrowse link
G SRF serum response factor ISO RGD PMID:9570363 RGD:1581428 NCBI chr 6:43,171,269...43,181,506
Ensembl chr 6:43,171,269...43,181,506 		JBrowse link
G SRPX sushi repeat containing protein X-linked EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:38,149,339...38,220,871
Ensembl chr  X:38,149,336...38,220,924 		JBrowse link
G SRSF1 serine and arginine rich splicing factor 1 ISO mRNA:increased expression:liver (human) RGD PMID:23633480 RGD:9685423 NCBI chr17:57,989,038...58,007,246
Ensembl chr17:58,000,919...58,007,346 		JBrowse link
G SRSF2 serine and arginine rich splicing factor 2 disease_progression
treatment 		ISO
IEP
IMP 		RGD PMID:32372053 PMID:29278882 PMID:28082404 RGD:150429663, RGD:150429692, RGD:150429666 NCBI chr17:76,734,115...76,737,411
Ensembl chr17:76,734,115...76,737,333 		JBrowse link
G SSX1 SSX family member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:48,255,392...48,267,444
Ensembl chr  X:48,255,392...48,267,444 		JBrowse link
G ST6GAL1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 ISO protein:increased activity:liver: RGD PMID:9331085 RGD:10043141 NCBI chr 3:186,930,526...187,078,553
Ensembl chr 3:186,930,325...187,078,553 		JBrowse link
G STAB2 stabilin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:103,587,273...103,766,719
Ensembl chr12:103,587,273...103,766,719 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22488367 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO protein:increased phosphorylation:liver (mouse) RGD PMID:28100771 RGD:127285675 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G STAT4 signal transducer and activator of transcription 4 susceptibility EXP
IAGP 		CTD Direct Evidence: marker/mechanism
Hepatitis B, Chronic; DNA:SNP: intron 3: (rs7574865) (human) 		CTD
RGD		 PMID:23242368 PMID:26745093 RGD:11553302 NCBI chr 2:191,029,576...191,151,596
Ensembl chr 2:191,029,576...191,178,435 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A ameliorates ISO RGD PMID:28100771 RGD:127285675 NCBI chr17:42,287,439...42,311,943
Ensembl chr17:42,287,547...42,311,943 		JBrowse link
G STAT5B signal transducer and activator of transcription 5B exacerbates
ameliorates 		IEP protein:increased expression:liver (human)
mRNA:increased expression:liver (human) 		RGD PMID:17047057 PMID:31485610 RGD:153298929, RGD:153298932 NCBI chr17:42,199,177...42,288,370
Ensembl chr17:42,199,176...42,288,633 		JBrowse link
G STC2 stanniocalcin 2 disease_progression IEP mRNA:increased expression:liver (human) RGD PMID:35693827 RGD:153344586 NCBI chr 5:173,314,723...173,328,414
Ensembl chr 5:173,314,723...173,328,447 		JBrowse link
G STIM1 stromal interaction molecule 1 IEP mRNA:increased expression:liver (human) RGD PMID:23211538 RGD:152995401 NCBI chr11:3,854,604...4,093,210
Ensembl chr11:3,854,527...4,093,210 		JBrowse link
G STMN1 stathmin 1 disease_progression EXP
IEP 		CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:28284560 PMID:28982915 RGD:21408578 NCBI chr 1:25,884,179...25,906,880
Ensembl chr 1:25,884,181...25,906,991 		JBrowse link
G TACC3 transforming acidic coiled-coil containing protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 4:1,721,521...1,745,171
Ensembl chr 4:1,712,858...1,745,171 		JBrowse link
G TAGLN2 transgelin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 1:159,918,111...159,925,507
Ensembl chr 1:159,918,107...159,925,507 		JBrowse link
G TALDO1 transaldolase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19436114 NCBI chr11:747,464...765,012
Ensembl chr11:747,415...765,012 		JBrowse link
G TATDN1 TatD DNase domain containing 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr 8:124,488,494...124,539,088
Ensembl chr 8:124,488,485...124,539,458 		JBrowse link
G TBX3 T-box transcription factor 3 ameliorates
disease_progression
severity 		ISO
IEP 		human cells in mouse model
protein:increased expression:liver (human) 		RGD PMID:33577921 PMID:22811581 PMID:26922018 PMID:30578408 PMID:29295731 RGD:151361112, RGD:151361132, RGD:151361123, RGD:151361122, RGD:151361114 NCBI chr12:114,670,255...114,684,175
Ensembl chr12:114,670,255...114,684,175 		JBrowse link
G TCF19 transcription factor 19 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 6:31,158,589...31,164,215
Ensembl chr 6:31,158,331...31,167,159 		JBrowse link
G TCIM transcriptional and immune response regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:40,153,482...40,155,310
Ensembl chr 8:40,153,482...40,155,310 		JBrowse link
G TEDC2 tubulin epsilon and delta complex 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr16:2,460,109...2,464,963
Ensembl chr16:2,460,086...2,464,963 		JBrowse link
G TEK TEK receptor tyrosine kinase ISO protein:increased expression RGD PMID:16951510 RGD:1601490 NCBI chr 9:27,109,225...27,230,174
Ensembl chr 9:27,109,141...27,230,174 		JBrowse link
G TEP1 telomerase associated protein 1 disease_progression
susceptibility 		IAGP associated with hepatitis B;DNA:SNPs: :rs1713449,rs1760898, rs872072 (human)
DNA:SNP:intron:rs1760893(human) 		RGD PMID:23907815 PMID:27305982 RGD:152975963, RGD:152977750 NCBI chr14:20,365,667...20,413,501
Ensembl chr14:20,365,667...20,413,501 		JBrowse link
G TERT telomerase reverse transcriptase disease_progression
susceptibility
no_association
treatment 		ISO
IAGP
IEP
IDA
EXP 		protein:increased expression, increased localization:nucleus
ClinVar Annotator: match by term: Hepatocellular carcinoma
associated with hepatitis B;DNA:SNP: :rs13167280 (human)
DNA:SNPs::rs2736098(human)
mRNA:increased expression:liver
DNA:hypermethylation:promoter
DNA:SNP,mutations:promoter:rs2853669 (-245T >C), (-124C > T),(-146C > T)human
DNA:mutations, polymorphisms:promoter,intron, exon:rs2736100,rs2736098(human)
DNA:mutations:promoter:
CTD Direct Evidence: marker/mechanism 		ClinVar
CTD
RGD		 PMID:16651430 PMID:22634754 PMID:23000435 PMID:25362482 PMID:25741868 More... RGD:11038673, RGD:152975963, RGD:150530496, RGD:11530743, RGD:11530743, RGD:11564803, RGD:14696770, RGD:14696769, RGD:14696768, RGD:14696767 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068 		JBrowse link
G TET1 tet methylcytosine dioxygenase 1 IEP protein:decreased expression:liver RGD PMID:23671639 RGD:9586747 NCBI chr10:68,560,337...68,694,487
Ensembl chr10:68,560,337...68,694,487 		JBrowse link
G TET2 tet methylcytosine dioxygenase 2 severity
disease_progression
ameliorates 		IEP
HEP
IMP 		mRNA, protein:increased expression:liver (human)
mRNA:decreased expression:liver (human)
human cells in mouse model
mRNA, protein:decreased expression:liver (human) 		RGD PMID:29331390 PMID:30070373 PMID:26366235 PMID:33097695 PMID:33097695 More... RGD:150429595, RGD:150429689, RGD:150429684, RGD:150429597, RGD:150429597, RGD:150429595 NCBI chr 4:105,145,875...105,279,803
Ensembl chr 4:105,145,875...105,279,816 		JBrowse link
G TFPI2 tissue factor pathway inhibitor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17464989 PMID:28284560 NCBI chr 7:93,885,396...93,890,753
Ensembl chr 7:93,885,396...93,890,753 		JBrowse link
G TFRC transferrin receptor ISO mRNA:increased expression:liver RGD PMID:16953838 RGD:2292036 NCBI chr 3:196,049,284...196,082,090
Ensembl chr 3:196,012,511...196,082,153 		JBrowse link
G TGFA transforming growth factor alpha ISO
EXP 		associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism 		CTD
RGD		 PMID:9029167 PMID:15565109 PMID:9060843 RGD:2317471 NCBI chr 2:70,447,284...70,553,826
Ensembl chr 2:70,447,284...70,554,193 		JBrowse link
G TGFB1 transforming growth factor beta 1 EXP
ISO 		CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver (mouse) 		CTD
RGD		 PMID:9029167 PMID:28100771 RGD:127285675 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TGFB2 transforming growth factor beta 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:33010264 NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO mRNA, protein:decreased expression:liver RGD PMID:14585397 RGD:1601598 NCBI chr 3:30,606,356...30,694,142
Ensembl chr 3:30,606,478...30,694,249 		JBrowse link
G TGM3 transglutaminase 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:2,296,001...2,341,079
Ensembl chr20:2,296,001...2,341,079 		JBrowse link
G TH tyrosine hydroxylase EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815 		JBrowse link
G THEM4 thioesterase superfamily member 4 EXP CTD Direct Evidence: therapeutic CTD PMID:23392203 NCBI chr 1:151,870,866...151,909,511
Ensembl chr 1:151,870,866...151,909,637 		JBrowse link
G THY1 Thy-1 cell surface antigen EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:119,415,476...119,424,985
Ensembl chr11:119,415,476...119,424,985 		JBrowse link
G TICRR TOPBP1 interacting checkpoint and replication regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:89,575,469...89,628,023
Ensembl chr15:89,575,469...89,631,056 		JBrowse link
G TIMD4 T cell immunoglobulin and mucin domain containing 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:156,919,292...156,963,226
Ensembl chr 5:156,919,292...156,963,226 		JBrowse link
G TK1 thymidine kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:78,174,079...78,187,204
Ensembl chr17:78,174,091...78,187,233 		JBrowse link
G TLR2 toll like receptor 2 susceptibility IAGP
ISO 		associated with Hepatitis C, Chronic;DNA:deletion:promoter:-196 to -174(human) RGD PMID:21500195 PMID:22859216 PMID:27183918 RGD:15090813, RGD:18337266, RGD:15090815 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260 		JBrowse link
G TLR3 toll like receptor 3 disease_progression IEP RGD PMID:23197495 RGD:21079421 NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,068,911...186,088,073 		JBrowse link
G TLR4 toll like receptor 4 susceptibility EXP
IAGP
IEP 		CTD Direct Evidence: marker/mechanism
DNA:SNPs, haplotype: :multiples
DNA:SNP: :rs1057317(human)
protein:increased expression:liver: 		CTD
RGD		 PMID:27022031 PMID:21559380 PMID:25179842 PMID:28578348 RGD:14700558, RGD:14700557, RGD:14700552 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR7 toll like receptor 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24990399 NCBI chr  X:12,867,072...12,890,361
Ensembl chr  X:12,867,072...12,890,361 		JBrowse link
G TLR9 toll like receptor 9 treatment IEP
EXP
IMP 		protein: increased expression:peripheral blood mononuclear cell (human)
CTD Direct Evidence: marker/mechanism
human cells in a mouse model 		CTD
RGD		 PMID:24990399 PMID:18215354 PMID:24452201 RGD:18337472, RGD:18337468 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
G TMEM70 transmembrane protein 70 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27914986 NCBI chr 8:73,976,195...73,982,783
Ensembl chr 8:73,972,437...73,982,783 		JBrowse link
G TNF tumor necrosis factor disease_progression EXP
ISO
IAGP 		CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:liver, blood serum (mouse) 		CTD
RGD		 PMID:27022031 PMID:26569409 PMID:26890368 RGD:11344640, RGD:14975171 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 sexual_dimorphism
ameliorates 		ISO
IEP 		mRNA:decreased expression:liver (human)
mRNA,protein:increased expression:liver (human)
protein:decreased expression:liver (human) 		RGD PMID:27253414 PMID:29190981 PMID:26538215 PMID:32015333 RGD:151347600, RGD:151347622, RGD:151347618, RGD:151347604 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
G TNFSF10 TNF superfamily member 10 EXP CTD Direct Evidence: therapeutic CTD PMID:17326159 NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475 		JBrowse link
G TNFSF9 TNF superfamily member 9 ISO RGD PMID:17325342 RGD:2317348 NCBI chr19:6,531,026...6,535,924
Ensembl chr19:6,531,026...6,535,924 		JBrowse link
G TNIK TRAF2 and NCK interacting kinase disease_progression HEP protein:increased phosphorylation:liver, nucleus (human) RGD PMID:25160513 RGD:151347837 NCBI chr 3:171,058,414...171,460,408
Ensembl chr 3:171,058,414...171,460,408 		JBrowse link
G TONSL tonsoku like, DNA repair protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 8:144,428,775...144,444,440
Ensembl chr 8:144,428,775...144,444,440 		JBrowse link
G TOP2A DNA topoisomerase II alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896 		JBrowse link
G TP53 tumor protein p53 treatment ISO
IAGP
EXP 		protein:altered localization:cytoplasm, nucleus
ClinVar Annotator: match by term: Hepatocellular carcinoma
ClinVar Annotator: match by term: Hepatocellular cancer
mRNA:increased expression:liver (mouse)
DNA:missense mutation: :p.R249S (human)
CTD Direct Evidence: marker/mechanism|therapeutic 		OMIM
ClinVar
CTD
RGD		 PMID:1349102 PMID:1565143 PMID:1565144 PMID:1591732 PMID:1631137 More... RGD:1302543, RGD:152998960, RGD:127285675, RGD:14995934, RGD:14995503 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TP73 tumor protein p73 exacerbates
treatment 		IEP protein:decreased phosphorylation:liver (human)
human cells in a mouse model
mRNA:increased expression:liver (human) 		RGD PMID:27359056 PMID:25371988 PMID:19664633 PMID:14760085 PMID:31429776 RGD:151347579, RGD:151347596, RGD:151347594, RGD:151347593, RGD:151347592 NCBI chr 1:3,652,516...3,736,201
Ensembl chr 1:3,652,516...3,736,201 		JBrowse link
G TPX2 TPX2 microtubule nucleation factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:31,739,290...31,801,800
Ensembl chr20:31,739,271...31,801,805 		JBrowse link
G TRAF7 TNF receptor associated factor 7 treatment IEP
IMP 		mRNA:increased expression:liver RGD PMID:31730901 PMID:31730901 RGD:151356961, RGD:151356961 NCBI chr16:2,155,782...2,178,129
Ensembl chr16:2,155,698...2,178,129 		JBrowse link
G TRAIP TRAF interacting protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:49,828,601...49,856,564
Ensembl chr 3:49,828,601...49,856,574 		JBrowse link
G TRIM24 tripartite motif containing 24 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18026104 NCBI chr 7:138,460,259...138,589,996
Ensembl chr 7:138,460,259...138,589,996 		JBrowse link
G TRIP13 thyroid hormone receptor interactor 13 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:892,884...919,348
Ensembl chr 5:892,884...919,357 		JBrowse link
G TROAP trophinin associated protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr12:49,323,255...49,331,731
Ensembl chr12:49,323,236...49,331,731 		JBrowse link
G TSC1 TSC complex subunit 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21499249 NCBI chr 9:132,891,349...132,945,378
Ensembl chr 9:132,891,348...132,946,874 		JBrowse link
G TSC2 TSC complex subunit 2 severity IEP protein:decreased expression:liver (human) RGD PMID:24119083 RGD:21079731 NCBI chr16:2,047,985...2,089,491
Ensembl chr16:2,047,967...2,089,491 		JBrowse link
G TSLP thymic stromal lymphopoietin EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 5:111,070,062...111,078,026
Ensembl chr 5:111,070,062...111,078,026 		JBrowse link
G TSPY1 testis specific protein Y-linked 1 IEP mRNA:increased expression:liver RGD PMID:16106251 RGD:2315447 NCBI chr  Y:9,466,955...9,469,749
Ensembl chr  Y:9,466,955...9,469,749 		JBrowse link
G TST thiosulfate sulfurtransferase EXP CTD Direct Evidence: marker/mechanism CTD PMID:21472284 NCBI chr22:37,010,859...37,020,183
Ensembl chr22:37,010,859...37,020,183 		JBrowse link
G TTC36 tetratricopeptide repeat domain 36 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr11:118,527,474...118,530,993
Ensembl chr11:118,527,472...118,531,197 		JBrowse link
G TTK TTK protein kinase disease_progression EXP
IEP 		CTD Direct Evidence: marker/mechanism
mRNA:increased expression:liver (human) 		CTD
RGD		 PMID:28284560 PMID:35693827 RGD:153344586 NCBI chr 6:80,004,649...80,042,527
Ensembl chr 6:80,003,887...80,042,527 		JBrowse link
G TTR transthyretin disease_progression IEP
ISO 		protein:decreased expression:blood serum (human)
protein:increased expression:blood serum (rat)
protein:increased expression:blood serum (human) 		RGD PMID:29534342 PMID:28876464 PMID:28876464 PMID:16240287 RGD:151356736, RGD:151664602, RGD:151664602, RGD:151665161 NCBI chr18:31,591,877...31,598,821
Ensembl chr18:31,557,009...31,598,833 		JBrowse link
G TXNIP thioredoxin interacting protein ISS OMIM:114550 MouseDO NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579 		JBrowse link
G TYMS thymidylate synthetase susceptibility EXP
IAGP 		CTD Direct Evidence: marker/mechanism
DNA:deletion:3'UTR:1494del6(human) 		CTD
RGD		 PMID:18019677 PMID:18230555 PMID:17659576 RGD:14696708 NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578 		JBrowse link
G UACA uveal autoantigen with coiled-coil domains and ankyrin repeats ISS OMIM:114550 MouseDO NCBI chr15:70,654,554...70,778,903
Ensembl chr15:70,654,554...70,763,558 		JBrowse link
G UBD ubiquitin D EXP CTD Direct Evidence: marker/mechanism CTD PMID:19363144 NCBI chr 6:29,555,515...29,559,732
Ensembl chr 6:29,555,515...29,559,732 		JBrowse link
G UBE2C ubiquitin conjugating enzyme E2 C EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr20:45,812,644...45,816,952
Ensembl chr20:45,812,576...45,816,957 		JBrowse link
G UBE2E2 ubiquitin conjugating enzyme E2 E2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27914986 NCBI chr 3:23,203,098...23,591,925
Ensembl chr 3:23,203,020...23,591,794 		JBrowse link
G UBE2T ubiquitin conjugating enzyme E2 T EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 1:202,331,657...202,341,936
Ensembl chr 1:202,331,544...202,341,984 		JBrowse link
G UBR5 ubiquitin protein ligase E3 component n-recognin 5 treatment ISO RGD PMID:32087767 RGD:151665344 NCBI chr 8:102,252,273...102,412,700
Ensembl chr 8:102,252,273...102,412,759 		JBrowse link
G UCHL1 ubiquitin C-terminal hydrolase L1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18666234 NCBI chr 4:41,256,928...41,268,455
Ensembl chr 4:41,256,413...41,268,455 		JBrowse link
G UHRF1 ubiquitin like with PHD and ring finger domains 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr19:4,903,080...4,962,154
Ensembl chr19:4,903,080...4,962,154 		JBrowse link
G UMPS uridine monophosphate synthetase EXP CTD Direct Evidence: marker/mechanism CTD PMID:18230555 NCBI chr 3:124,730,452...124,749,273
Ensembl chr 3:124,730,433...124,749,273 		JBrowse link
G UROC1 urocanate hydratase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:126,481,166...126,517,773
Ensembl chr 3:126,481,166...126,517,773 		JBrowse link
G USP2 ubiquitin specific peptidase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21147110 NCBI chr11:119,355,215...119,381,690
Ensembl chr11:119,355,215...119,381,711 		JBrowse link
G USP4 ubiquitin specific peptidase 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:35841383 NCBI chr 3:49,277,144...49,340,053
Ensembl chr 3:49,277,144...49,340,712 		JBrowse link
G VASN vasorin EXP CTD Direct Evidence: marker/mechanism CTD PMID:25826090 NCBI chr16:4,371,848...4,383,538
Ensembl chr16:4,371,848...4,383,538 		JBrowse link
G VAV1 vav guanine nucleotide exchange factor 1 ISO mRNA:decreased expression:liver RGD PMID:2064726 RGD:2306008 NCBI chr19:6,772,708...6,857,361
Ensembl chr19:6,772,708...6,857,366 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22922871 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045 		JBrowse link
G VDR vitamin D receptor susceptibility IDA
IAGP 		DNA:hypermethylation:promoter
ClinVar Annotator: match by term: Hepatocellular cancer
ClinVar Annotator: match by term: Hepatocellular carcinoma
associated with alcoholic liver cirrhosis;DNA:haplotype::
associated with Hepatitis B, Chronic;DNA:SNP: :rs2228570(human) 		ClinVar
RGD		 PMID:24033266 PMID:25741868 PMID:28492532 PMID:29432829 PMID:20572305 More... RGD:14401747, RGD:14402026, RGD:14402025 NCBI chr12:47,841,537...47,904,994
Ensembl chr12:47,841,537...47,943,048 		JBrowse link
G VEGFA vascular endothelial growth factor A treatment
susceptibility
disease_progression 		IEP
ISO
IAGP 		protein:increased expression:liver
DNA:SNP: :2578C>A (human)
associated with liver cirrhosis;
associated with liver cirrhosis; protein:increased expression:platelet, liver:
protein:increased expression:serum:
DNA:polymorphism:promoter:-2578C>A (rs699947)(human) 		RGD PMID:27338800 PMID:25999787 PMID:24445728 PMID:18392108 PMID:16835748 More... RGD:15003194, RGD:152177911, RGD:126848814, RGD:15036790, RGD:15014783, RGD:11527070, RGD:15003200, RGD:15003196, RGD:15003196 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G VEGFC vascular endothelial growth factor C IEP associated with liver cirrhosis; protein:increased expression:liver: RGD PMID:18544126 RGD:15003200 NCBI chr 4:176,683,538...176,792,922
Ensembl chr 4:176,683,538...176,792,922 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor disease_progression IEP RGD PMID:31321740 RGD:155882550 NCBI chr 3:10,141,778...10,153,667
Ensembl chr 3:10,141,778...10,153,676 		JBrowse link
G VIPR1 vasoactive intestinal peptide receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:42,489,299...42,537,568
Ensembl chr 3:42,489,299...42,537,573 		JBrowse link
G VSIG4 V-set and immunoglobulin domain containing 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:66,021,738...66,040,080
Ensembl chr  X:66,021,738...66,040,125 		JBrowse link
G WDR62 WD repeat domain 62 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr19:36,054,897...36,111,145
Ensembl chr19:36,054,649...36,105,108 		JBrowse link
G WDR76 WD repeat domain 76 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr15:43,827,002...43,868,412
Ensembl chr15:43,826,980...43,868,412 		JBrowse link
G WNT2 Wnt family member 2 susceptibility IAGP associated with hepatitis B;DNA:SNP: :rs4730775(human) RGD PMID:28328801 RGD:14402040 NCBI chr 7:117,275,451...117,323,058
Ensembl chr 7:117,275,451...117,323,152 		JBrowse link
G WRAP53 WD repeat containing antisense to TP53 IEP RNA:increased expression:liver: RGD PMID:26551349 RGD:11096781 NCBI chr17:7,686,071...7,703,502
Ensembl chr17:7,686,071...7,703,502 		JBrowse link
G XAGE1B X antigen family member 1B EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr  X:52,512,077...52,517,068
Ensembl chr  X:52,512,077...52,520,803 		JBrowse link
G XDH xanthine dehydrogenase ISO protein:decreased activity:tumor (rat) RGD PMID:179860 RGD:5135059 NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742 		JBrowse link
G XPO1 exportin 1 ameliorates
exacerbates
treatment 		IMP
IEP
ISO 		human cell line in a mouse model
mRNA:increased expression:liver (human) 		RGD PMID:25030088 PMID:31371628 PMID:27013579 RGD:151665796, RGD:151667441, RGD:151667433 NCBI chr 2:61,477,849...61,538,612
Ensembl chr 2:61,476,032...61,538,741 		JBrowse link
G XPO5 exportin 5 severity IAGP DNA:snp, haplotype:3' utr:c.*659A>C (rs11077) (human) RGD PMID:24676133 RGD:11041737 NCBI chr 6:43,522,334...43,576,038
Ensembl chr 6:43,522,334...43,576,038 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 severity
susceptibility
disease_progression
no_association 		IEA
IAGP 		associated with Chronic Hepatitis C;DNA:SNP:exon 14: c.1517G>C, p.506G>A (human)
DNA:SNPs:exon 9, exon 15: c.910A>G, c.1686C>G (human)
DNA:SNP:exon 13: c.1471G>A, p.E491K (human)
DNA:SNPs:cds: 194C>T, 280A>G (human)
associated with Hepatitis C, Chronic;DNA:missense mutation:cds:p.R399Q (human)
associated with Hepatitis C, Chronic;DNA:missense mutation:cds:p.R194W (human)
associated with hepatitis B;DNA:missense mutation, haplotype:cds:p.R399Q (human)
DNA:missense mutations:cds:p.R194W, p.R280H, p.R399Q (human)
DNA:missense mutation:cds:p.R399Q (rs25487) (human)
DNA:SNPs:exons:c.1254C>T, c.1517G>C (human)
DNA:missense mutation:cds:c.1804C>A (p.G506A) (human)
DNA:missense mutation:cds:p.R399Q (28152G>A) (rs25487) (human)
DNA:silent mutation, missense mutation:cds:c.1161G>A, c.1779C>G (p.L387L, p.S593R) (human)
DNA:missense mutations:cds:c.482C>T, c.1178G>A (p.P161L, p.R393H) (human) 		GAD
RGD		 PMID:15118671 PMID:32334466 PMID:24634229 PMID:24446299 PMID:28927037 More... RGD:1331525, RGD:150540333, RGD:150540332, RGD:150530624, RGD:150530503, RGD:15036797, RGD:15036797, RGD:15036794, RGD:15014792, RGD:15014791, RGD:15014790, RGD:15014789, RGD:14985243, RGD:14985242, RGD:14985240, RGD:14985238, RGD:14696773, RGD:14696772, RGD:14696702 NCBI chr19:43,543,311...43,575,527
Ensembl chr19:43,543,311...43,580,473 		JBrowse link
G YAP1 Yes1 associated transcriptional regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:29698666 NCBI chr11:102,110,447...102,233,424
Ensembl chr11:102,110,447...102,233,424 		JBrowse link
G YTHDF2 YTH N6-methyladenosine RNA binding protein F2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28104805 NCBI chr 1:28,736,624...28,769,775
Ensembl chr 1:28,736,621...28,769,775 		JBrowse link
G YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta severity IEP RGD PMID:27811373 RGD:14700875 NCBI chr 8:100,916,523...100,953,382
Ensembl chr 8:100,916,523...100,953,388 		JBrowse link
G ZC3H12D zinc finger CCCH-type containing 12D EXP CTD Direct Evidence: marker/mechanism CTD PMID:34545456 NCBI chr 6:149,446,795...149,485,014
Ensembl chr 6:149,446,795...149,485,014 		JBrowse link
G ZFHX3 zinc finger homeobox 3 severity
disease_progression 		IMP
IEP 		human cell line in a mouse model
associated with Chronic Hepatitis B;protein:decreased expression:blood serum (human) 		RGD PMID:32277050 PMID:20534899 RGD:151361162, RGD:151361169 NCBI chr16:72,782,885...73,891,930
Ensembl chr16:72,782,885...73,891,871 		JBrowse link
G ZFP36 ZFP36 ring finger protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr19:39,406,847...39,409,407
Ensembl chr19:39,406,847...39,409,407 		JBrowse link
G ZIC2 Zic family member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:99,981,784...99,986,765
Ensembl chr13:99,981,784...99,986,765 		JBrowse link
G ZIC4 Zic family member 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr 3:147,386,046...147,406,543
Ensembl chr 3:147,386,046...147,406,809 		JBrowse link
G ZIC5 Zic family member 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr13:99,962,964...99,971,909
Ensembl chr13:99,962,964...99,971,767 		JBrowse link
G ZNF23 zinc finger protein 23 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21965783 NCBI chr16:71,447,597...71,462,247
Ensembl chr16:71,447,597...71,463,095 		JBrowse link
G ZWINT ZW10 interacting kinetochore protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:28284560 NCBI chr10:56,357,227...56,361,273
Ensembl chr10:56,357,227...56,361,273 		JBrowse link
hepatocellular clear cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 disease_progression IAGP DNA:misssense mutation:cds:p.Arg132Cys(human)
DNA:polymorphism: :rs12478635(human) 		RGD PMID:28403884 PMID:25355558 RGD:14974227, RGD:14974228 NCBI chr 2:208,236,227...208,255,071
Ensembl chr 2:208,236,229...208,266,074 		JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 disease_progression IAGP DNA:polymorphism: :rs11632348(human) RGD PMID:25355558 RGD:14974228 NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,477 		JBrowse link
G LEP leptin IEP mRNA:increased expression:liver: RGD PMID:20723213 RGD:14696785 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G LEPR leptin receptor IEP mRNA:increased expression:liver RGD PMID:20723213 RGD:14696785 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559 		JBrowse link
G TERT telomerase reverse transcriptase disease_progression IEP mRNA:increased expression:liver: RGD PMID:28460432 PMID:20723213 RGD:14696783, RGD:14696785 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068 		JBrowse link
intrahepatic cholangiocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APC APC regulator of WNT signaling pathway IAGP ClinVar Annotator: match by term: Intrahepatic cholangiocarcinoma ClinVar PMID:24728327 PMID:25479140 PMID:25741868 PMID:26467025 PMID:26530882 More... NCBI chr 5:112,707,498...112,846,239
Ensembl chr 5:112,707,518...112,846,239 		JBrowse link
G ARID1A AT-rich interaction domain 1A disease_progression
exacerbates 		IEP mRNA,protein:decreased expression:intrahepatic bile duct (human) RGD PMID:30849962 PMID:27433094 PMID:31665232 RGD:14974231, RGD:126775257, RGD:126781775 NCBI chr 1:26,696,015...26,782,104
Ensembl chr 1:26,693,236...26,782,104 		JBrowse link
G BAP1 BRCA1 associated deubiquitinase 1 disease_progression IEP RGD PMID:27864835 RGD:150340628 NCBI chr 3:52,401,008...52,410,008
Ensembl chr 3:52,401,008...52,410,008 		JBrowse link
G BECN1 beclin 1 disease_progression IEP RGD PMID:30849962 RGD:14974231 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase severity IAGP DNA:missense mutation:cds:p.V600E (human) RGD PMID:24139215 RGD:14398746 NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929 		JBrowse link
G FAS Fas cell surface death receptor disease_progression IEP RGD PMID:11003620 RGD:14700701 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FASLG Fas ligand severity IEP RGD PMID:11003620 RGD:14700701 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G FOXP3 forkhead box P3 ISO DNA:hypomethylation:liver RGD PMID:24291052 RGD:38599002 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 disease_progression IEP protein:increased expression:liver (human) RGD PMID:24796583 RGD:152177907 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699 		JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 disease_progression IEP protein:increased expression:liver (human) RGD PMID:24796583 RGD:152177907 NCBI chr 6:44,246,194...44,253,883
Ensembl chr 6:44,246,166...44,253,888 		JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 no_association IAGP DNA:misssense mutations:cds:p.Arg132Cys,Arg132Leu (human) RGD PMID:26245674 RGD:14974229 NCBI chr 2:208,236,227...208,255,071
Ensembl chr 2:208,236,229...208,266,074 		JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 disease_progression IAGP
ISO 		DNA:mutations: :
mRNA:decreased expression:liver (mouse) 		RGD PMID:22824796 PMID:32463951 RGD:14985256, RGD:149735894 NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,477 		JBrowse link
G KDM5C lysine demethylase 5C exacerbates HEP protein:decreased expression:bile duct (human) RGD PMID:32714863 RGD:151361175 NCBI chr  X:53,176,277...53,225,207
Ensembl chr  X:53,176,277...53,225,422 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase disease_progression ISS
IAGP 		DNA:mutations:: MouseDO
RGD		 PMID:24139215 RGD:14398746 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936 		JBrowse link
G LCN2 lipocalin 2 treatment ISO
IEP 		Protein:increased expression:bile duct RGD PMID:24939880 PMID:24939880 RGD:126790491, RGD:126790491 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G LRP1B LDL receptor related protein 1B exacerbates IAGP DNA:mutations:multiple: (human) RGD PMID:33014052 RGD:150429786 NCBI chr 2:140,231,423...142,131,016
Ensembl chr 2:140,231,423...142,131,016 		JBrowse link
G MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 disease_progression HEP protein:increased expression:intrahepatic bile duct (human) RGD PMID:30377796 RGD:152998946 NCBI chr 3:65,353,526...66,038,918
Ensembl chr 3:65,353,525...66,038,918 		JBrowse link
G MIR152 microRNA 152 IEP miRNA:decreased expression:intrahepatic bile duct RGD PMID:28921383 RGD:19165148 NCBI chr17:48,037,161...48,037,247
Ensembl chr17:48,037,161...48,037,247 		JBrowse link
G MIR200B microRNA 200b IEP RNA:increased expression:liver RGD PMID:27685844 RGD:14928335 NCBI chr 1:1,167,104...1,167,198
Ensembl chr 1:1,167,104...1,167,198 		JBrowse link
G MIR21 microRNA 21 IEP RNA:increased expression:liver,plasma RGD PMID:27685844 RGD:14928335 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G MIR221 microRNA 221 severity IEP RGD PMID:27685844 RGD:14928335 NCBI chr  X:45,746,157...45,746,266
Ensembl chr  X:45,746,157...45,746,266 		JBrowse link
G PBRM1 polybromo 1 disease_progression IEP
HEP 		protein:increased expression:intrahepatic bile duct (human) RGD PMID:27864835 PMID:30377796 RGD:150340628, RGD:152998946 NCBI chr 3:52,545,367...52,685,913
Ensembl chr 3:52,545,352...52,685,917 		JBrowse link
G PTEN phosphatase and tensin homolog disease_progression IEP protein:decreased expression:liver (human) RGD PMID:24796583 RGD:152177907 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G RNF43 ring finger protein 43 exacerbates IEP mRNA, protein:decreased expression:liver, bile duct epithelium (human) RGD PMID:26980022 RGD:151361125 NCBI chr17:58,352,500...58,417,534
Ensembl chr17:58,353,676...58,417,595 		JBrowse link
G RUNX1 RUNX family transcription factor 1 IEP mRNA:increased expression:intrahepatic bile duct RGD PMID:31015363 RGD:126775143 NCBI chr21:34,787,801...35,049,302
Ensembl chr21:34,787,801...36,004,667 		JBrowse link
G S100B S100 calcium binding protein B disease_progression HEP protein:increased expression:intrahepatic bile duct (human) RGD PMID:30377796 RGD:152998946 NCBI chr21:46,598,604...46,605,082
Ensembl chr21:46,598,604...46,605,208 		JBrowse link
G SMAD4 SMAD family member 4 disease_progression IEP mRNA,protein:decreased expression:intrahepatic bile duct RGD PMID:16917866 PMID:23981608 RGD:18936999, RGD:21066336 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,528...51,085,045 		JBrowse link
G TEP1 telomerase associated protein 1 IEP mRNA:increased expression:hepatocyte,biliary epithelium. RGD PMID:10498642 RGD:152977753 NCBI chr14:20,365,667...20,413,501
Ensembl chr14:20,365,667...20,413,501 		JBrowse link
G TERC telomerase RNA component IEP RNA:increased expression:hepatocyte,biliary epithelium. RGD PMID:10498642 RGD:152977753 NCBI chr 3:169,764,610...169,765,060
Ensembl chr 3:169,764,610...169,765,047
Ensembl chr 3:169,764,610...169,765,047 		JBrowse link
Klatskin's tumor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APC APC regulator of WNT signaling pathway IAGP ClinVar Annotator: match by term: Klatskin tumor ClinVar PMID:25741868 PMID:28492532 NCBI chr 5:112,707,498...112,846,239
Ensembl chr 5:112,707,518...112,846,239 		JBrowse link
G ARID1A AT-rich interaction domain 1A disease_progression IAGP DNA:deletions RGD PMID:33387086 RGD:126848756 NCBI chr 1:26,696,015...26,782,104
Ensembl chr 1:26,693,236...26,782,104 		JBrowse link
G GATA6 GATA binding protein 6 sexual_dimorphism IAGP DNA:mutations RGD PMID:33387086 RGD:126848756 NCBI chr18:22,169,589...22,202,528
Ensembl chr18:22,169,589...22,202,528 		JBrowse link
G KMT2C lysine methyltransferase 2C onset IAGP DNA:mutations RGD PMID:33387086 RGD:126848756 NCBI chr 7:152,134,925...152,436,003
Ensembl chr 7:152,134,922...152,436,644 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase disease_progression IAGP DNA:mutations RGD PMID:33387086 RGD:126848756 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936 		JBrowse link
G PREX2 phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 sexual_dimorphism IAGP DNA:substitutions, insertion/deletions: (human) RGD PMID:33387086 RGD:126848756 NCBI chr 8:67,952,046...68,237,032
Ensembl chr 8:67,952,046...68,237,032 		JBrowse link
liver cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 severity ISO mRNA:decreased expression:liver (mouse) RGD PMID:30580964 RGD:24922199 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155 		JBrowse link
G ABCB11 ATP binding cassette subfamily B member 11 ISO mRNA:decreased expression:liver RGD PMID:29651702 RGD:14402411 NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324 		JBrowse link
G ACOT12 acyl-CoA thioesterase 12 ISO RGD PMID:2566591 RGD:13831129 NCBI chr 5:81,308,609...81,394,134
Ensembl chr 5:81,329,996...81,394,179 		JBrowse link
G ADAM28 ADAM metallopeptidase domain 28 IEP mRNA:increased expression:liver RGD PMID:32782619 RGD:153297784 NCBI chr 8:24,294,069...24,359,014
Ensembl chr 8:24,294,069...24,359,014 		JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member ISO DNA:missense mutation:cds:p.E487K (mouse) RGD PMID:26150517 RGD:14696779 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532 		JBrowse link
G ATM ATM serine/threonine kinase ameliorates ISO RGD PMID:19919837 RGD:150340702 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102 		JBrowse link
G CCND1 cyclin D1 disease_progression ISO protein:increased expression:liver (rat) RGD PMID:11797828 RGD:151356973 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CCND2 cyclin D2 disease_progression IDA RGD PMID:30308939 RGD:151665105 NCBI chr12:4,273,762...4,305,353
Ensembl chr12:4,269,771...4,305,353 		JBrowse link
G CCNE1 cyclin E1 disease_progression ISO protein:increased expression:liver (rat) RGD PMID:11797828 RGD:151356973 NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312 		JBrowse link
G CDH1 cadherin 1 ISO mRNA:increased expression:liver (mouse) RGD PMID:25319454 RGD:152995431 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537 		JBrowse link
G CES1 carboxylesterase 1 treatment ISO RGD PMID:27523631 RGD:152995275 NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex IMP human cells in mouse model RGD PMID:27367027 RGD:153305911 NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596 		JBrowse link
G GPT glutamic--pyruvic transaminase treatment IEP RGD PMID:22922605 RGD:14975251 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174 		JBrowse link
G GPT2 glutamic--pyruvic transaminase 2 treatment IEP RGD PMID:22922605 RGD:14975251 NCBI chr16:46,884,362...46,931,289
Ensembl chr16:46,884,362...46,931,289 		JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO DNA:missense mutations:cds:p.Q61L, p.Q61K, p.Q61R (mouse) RGD PMID:9142214 RGD:14688053 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta IMP human cells in mouse model RGD PMID:27367027 RGD:153305911 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma IMP human cells in mouse model RGD PMID:27367027 RGD:153305911 NCBI chr  X:154,541,238...154,565,046
Ensembl chr  X:154,541,199...154,565,046 		JBrowse link
G IL10 interleukin 10 IEP RGD PMID:30610790 RGD:14975253 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G JAG1 jagged canonical Notch ligand 1 treatment ISO miRNA:decreased expression:liver RGD PMID:25311838 RGD:14694834 NCBI chr20:10,637,684...10,673,999
Ensembl chr20:10,637,684...10,673,999 		JBrowse link
G JAK2 Janus kinase 2 severity IEP
IMP 		mRNA:increased expression:liver,serum (human)
human cell line in a mouse model 		RGD PMID:27788478 PMID:27788478 RGD:18182929, RGD:18182929 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948 		JBrowse link
G KRT18 keratin 18 severity ISO associated with fatty liver disease RGD PMID:27689336 RGD:18337485 NCBI chr12:52,948,855...52,952,906
Ensembl chr12:52,948,871...52,952,906 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 exacerbates ISO RGD PMID:17468757 RGD:151665350 NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,752...36,122,511 		JBrowse link
G PCNA proliferating cell nuclear antigen disease_progression ISO protein:increased expression:liver (rat) RGD PMID:11797828 RGD:151356973 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha susceptibility ISO RGD PMID:20583210 RGD:14402407 NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093 		JBrowse link
G SETD2 SET domain containing 2, histone lysine methyltransferase IEP protein:decreased expression:liver (human) RGD PMID:26172293 RGD:11530741 NCBI chr 3:47,016,436...47,164,840
Ensembl chr 3:47,016,428...47,164,113 		JBrowse link
G SLCO1B1 solute carrier organic anion transporter family member 1B1 disease_progression IEP mRNA:decreased expression:liver (human) RGD PMID:21625523 RGD:152995425 NCBI chr12:21,131,194...21,239,796
Ensembl chr12:21,131,194...21,239,796 		JBrowse link
G SLCO1B3 solute carrier organic anion transporter family member 1B3 ISO mRNA:decreased expression:liver (mouse) RGD PMID:25319454 RGD:152995431 NCBI chr12:20,810,705...20,916,911
Ensembl chr12:20,810,702...20,916,911 		JBrowse link
G SLCO2B1 solute carrier organic anion transporter family member 2B1 disease_progression IEP mRNA:decreased expression:liver (human) RGD PMID:21625523 RGD:152995425 NCBI chr11:75,151,107...75,206,549
Ensembl chr11:75,100,563...75,206,549 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 severity IEP mRNA:increased expression:liver (human) RGD PMID:30088263 RGD:15036795 NCBI chr19:43,543,311...43,575,527
Ensembl chr19:43,543,311...43,580,473 		JBrowse link
liver carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7B ATPase copper transporting beta ISO RGD PMID:11509115 RGD:1302456 NCBI chr13:51,932,669...52,012,132
Ensembl chr13:51,930,436...52,012,125 		JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 ameliorates ISO DNA:deletion:exons: RGD PMID:24293323 RGD:150429711 NCBI chr 1:162,630,863...162,787,405
Ensembl chr 1:162,631,373...162,787,405 		JBrowse link
G HMBS hydroxymethylbilane synthase sexual_dimorphism ISO Protein:increased activity:liver (rat) RGD PMID:1781034 RGD:25440495 NCBI chr11:119,084,881...119,093,549
Ensembl chr11:119,084,866...119,093,834 		JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO DNA:hypomethylation RGD PMID:3345576 RGD:14694848 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321 		JBrowse link
G IL10 interleukin 10 IAGP DNA:SNP:promoter:-592C>A (rs1800872) (human) RGD PMID:28763918 RGD:14975157 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G NRAS NRAS proto-oncogene, GTPase IEP mRNA:increased expression:liver (human) RGD PMID:3018923 RGD:14975106 NCBI chr 1:114,704,469...114,716,771
Ensembl chr 1:114,704,469...114,716,771 		JBrowse link
G PDCD10 programmed cell death 10 IEP protein:increased expression:liver (human) RGD PMID:32186778 RGD:401827111 NCBI chr 3:167,683,298...167,734,892
Ensembl chr 3:167,683,298...167,734,939 		JBrowse link
Liver Metastasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme ISO associated with colorectal cancer;mRNA:increased expression:liver (mouse) RGD PMID:20380732 RGD:25671446 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase severity IAGP associated with colorectal cancer;DNA:mutation:cds:
associated with colorectal cancer;DNA:mutations:multiple
associated with skin melanoma;DNA:missense mutations:cds:
associated with colorectal cancer;DNA:missense mutations:cds:pV599E,p.V600E (human)
associated with colorectal cancer;DNA:missense mutation:cds:p.V600E (human) 		RGD PMID:27737491 PMID:26775732 PMID:28787433 PMID:22331825 PMID:23010994 RGD:18337264, RGD:11554843, RGD:14696791, RGD:18337265, RGD:15039394 NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 disease_progression IEP associated with colorectal cancer RGD PMID:27058904 RGD:14995463 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 treatment ISO associated with Animal Mammary Neoplasms; RGD PMID:15692764 RGD:14995455 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCND2 cyclin D2 IEP associated with colorectal cancer;protein:increased expression:colorectum RGD PMID:19508551 RGD:151665111 NCBI chr12:4,273,762...4,305,353
Ensembl chr12:4,269,771...4,305,353 		JBrowse link
G CCNG1 cyclin G1 treatment IMP human cells in mouse model RGD PMID:10910035 RGD:151356987 NCBI chr 5:163,437,571...163,457,640
Ensembl chr 5:163,437,569...163,448,199 		JBrowse link
G CD44 CD44 molecule (IN blood group) IEP associated with Breast Neoplasm;protein:increased expression:liver RGD PMID:17991717 RGD:2289349 NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402 		JBrowse link
G CHD4 chromodomain helicase DNA binding protein 4 ameliorates IMP associated with human colon adenocarcinoma cells in a mouse model RGD PMID:28486105 RGD:153323299 NCBI chr12:6,570,082...6,607,379
Ensembl chr12:6,570,082...6,614,524 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 treatment ISO associated with colon carcinoma; RGD PMID:30381616 RGD:27095891 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 ameliorates IEP associated with colorectal cancer; human cells in mouse model RGD PMID:30789971 RGD:151893289 NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 IMP associated with colorectal cancer; human colon adenocarcinoma cells in a mouse model RGD PMID:29679563 RGD:26884358 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 ameliorates IEP
IMP 		associated with colorectal cancer; human cells in mouse model
human cells in mouse model; associated with colorectal cancer 		RGD PMID:30789971 PMID:29436696 RGD:151893289, RGD:152023643 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177 		JBrowse link
G DAXX death domain associated protein exacerbates IEP
IAGP 		associated with colon cancer; mRNA:decreased expression:liver (human)
associated with pancreatic endocrine carcinoma;DNA:mutations:CDS:multiple (human)
associated with neuroendocrine tumor;DNA:mutations:CDS:multiple (human) 		RGD PMID:31942198 PMID:30339629 PMID:30342802 RGD:152025194, RGD:152025203, RGD:152025199 NCBI chr 6:33,318,558...33,322,959
Ensembl chr 6:33,318,558...33,323,016 		JBrowse link
G DDR1 discoidin domain receptor tyrosine kinase 1 treatment ISO
IMP 		mRNA:increased expression:liver (mouse)
human cells in mouse model; nilotinib 		RGD PMID:33110221 PMID:30666650 PMID:29438985 RGD:151347537, RGD:151347840, RGD:151347685 NCBI chr 6:30,880,970...30,900,156
Ensembl chr 6:30,876,421...30,900,156 		JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 ameliorates ISO
IMP 		associated with colon carcinoma
associated with melanoma; 		RGD PMID:22071959 PMID:21701781 RGD:150429701, RGD:150429713 NCBI chr 1:162,630,863...162,787,405
Ensembl chr 1:162,631,373...162,787,405 		JBrowse link
G DOCK6 dedicator of cytokinesis 6 ameliorates IMP associated with stomach cancer; RGD PMID:29587866 RGD:155791564 NCBI chr19:11,199,295...11,262,524
Ensembl chr19:11,199,295...11,262,524 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 disease_progression IEP associated with colorectal cancer; RGD PMID:28846828 RGD:21408566 NCBI chr 4:152,320,544...152,536,092
Ensembl chr 4:152,320,544...152,536,092 		JBrowse link
G FGFR1 fibroblast growth factor receptor 1 IEP associated with colorectal cancer;mRNA:increased expression:colorectal mucosa: RGD PMID:19082464 RGD:25330357 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834 		JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit IMP human cells in mouse model RGD PMID:30114390 RGD:153344554 NCBI chr 2:28,392,858...28,417,317
Ensembl chr 2:28,392,448...28,417,317 		JBrowse link
G GPC3 glypican 3 IEP protein:increased expression:blood serum (human) RGD PMID:28801286 RGD:243065135 NCBI chr  X:133,535,745...133,985,594
Ensembl chr  X:133,535,745...133,987,100 		JBrowse link
G HMBS hydroxymethylbilane synthase ISO associated with colon adenocarcinoma;protein:decreased activity:liver(rat) RGD PMID:1386052 RGD:25440496 NCBI chr11:119,084,881...119,093,549
Ensembl chr11:119,084,866...119,093,834 		JBrowse link
G IL2 interleukin 2 treatment IDA associated with Colorectal Neoplasms, Carcinoma, Hepatocellular;
associated with colon carcinoma 		RGD PMID:11591892 PMID:9354462 RGD:8663446, RGD:14928215 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IQSEC1 IQ motif and Sec7 domain ArfGEF 1 IMP human cells in mouse model RGD PMID:22662237 RGD:153344589 NCBI chr 3:12,897,043...13,283,257
Ensembl chr 3:12,897,043...13,283,281 		JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 IEP associated with colon cancer;protein:increased expression:colon (human) RGD PMID:24533778 RGD:155259116 NCBI chr19:7,903,877...7,914,478
Ensembl chr19:7,903,843...7,914,478 		JBrowse link
G MIR141 microRNA 141 IEP associated with colorectal cancer;RNA:increased expression:liver: RGD PMID:28617555 RGD:14928321 NCBI chr12:6,964,097...6,964,191
Ensembl chr12:6,964,097...6,964,191 		JBrowse link
G MIR148B microRNA 148b exacerbates IMP associated with stomach cancer; RGD PMID:29587866 RGD:155791564 NCBI chr12:54,337,216...54,337,314
Ensembl chr12:54,337,216...54,337,314 		JBrowse link
G MIR155 microRNA 155 IEP RGD PMID:26885061 RGD:21079444 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044 		JBrowse link
G MIR200B microRNA 200b IEP associated with colorectal cancer;RNA:increased expression:liver: RGD PMID:28617555 RGD:14928321 NCBI chr 1:1,167,104...1,167,198
Ensembl chr 1:1,167,104...1,167,198 		JBrowse link
G MIR200C microRNA 200c IEP associated with colorectal cancer;RNA:increased expression:liver: RGD PMID:28617555 RGD:14928321 NCBI chr12:6,963,699...6,963,766
Ensembl chr12:6,963,699...6,963,766 		JBrowse link
G MIR223 microRNA 223 disease_progression IEP associated with colorectal cancer; RGD PMID:28846828 RGD:21408566 NCBI chr  X:66,018,870...66,018,979
Ensembl chr  X:66,018,870...66,018,979 		JBrowse link
G MIR494 microRNA 494 exacerbates IMP associated with pancreatic ductal adenocarcinoma; RGD PMID:24859161 RGD:156430321 NCBI chr14:101,029,634...101,029,714
Ensembl chr14:101,029,634...101,029,714 		JBrowse link
G MIR597 microRNA 597 IMP human cells in mouse model RGD PMID:31245295 RGD:153344552 NCBI chr 8:9,741,672...9,741,768
Ensembl chr 8:9,741,672...9,741,768 		JBrowse link
G MPL MPL proto-oncogene, thrombopoietin receptor severity
exacerbates 		ISO
IEP 		associated with pancreatic ductal adenocarcinoma; human cells in mouse model
associated with colorectal carcinoma;protein:increased expression:colorectum (human)
associated with pancreatic cancer; protein:increased expression:liver, pancreas (human) 		RGD PMID:30770989 PMID:23747337 PMID:30770989 RGD:126925751, RGD:126925752, RGD:126925751 NCBI chr 1:43,337,818...43,354,466
Ensembl chr 1:43,337,818...43,354,466 		JBrowse link
G NRAS NRAS proto-oncogene, GTPase susceptibility IAGP human gene in a mouse model;DNA:missense mutations:cds:p.G12V, p.Q61K (human)
associated with colorectal cancer;DNA:mutations:exons (human)
associated with melanoma;DNA:mutations: exons (human) 		RGD PMID:26799184 PMID:28011498 PMID:28787433 RGD:14696774, RGD:14696792, RGD:14696791 NCBI chr 1:114,704,469...114,716,771
Ensembl chr 1:114,704,469...114,716,771 		JBrowse link
G PTPRB protein tyrosine phosphatase receptor type B treatment ISO mouse tumor cells in mouse recipient RGD PMID:31348125 RGD:151660353 NCBI chr12:70,515,870...70,637,429
Ensembl chr12:70,515,870...70,637,440 		JBrowse link
G RICTOR RPTOR independent companion of MTOR complex 2 disease_progression ISO
IEP 		mRNA:increased expression:liver (human) RGD PMID:30404068 PMID:30404068 RGD:152995463, RGD:152995463 NCBI chr 5:38,937,920...39,074,399
Ensembl chr 5:38,937,920...39,074,402 		JBrowse link
G RNF43 ring finger protein 43 IEP associated with colorectal adenocarcinoma;mRNA:increased expression:liver (human) RGD PMID:28789449 RGD:151361221 NCBI chr17:58,352,500...58,417,534
Ensembl chr17:58,353,676...58,417,595 		JBrowse link
G SLC3A2 solute carrier family 3 member 2 severity ISO associated with colon adenocarcinoma RGD PMID:11745822 RGD:151361130 NCBI chr11:62,856,109...62,888,860
Ensembl chr11:62,856,004...62,888,880 		JBrowse link
G SLC7A5 solute carrier family 7 member 5 severity ISO associated with colon cancer
associated with colon adenocarcinoma 		RGD PMID:11718450 PMID:11745822 RGD:151361129, RGD:151361130 NCBI chr16:87,830,023...87,869,507
Ensembl chr16:87,830,016...87,869,507 		JBrowse link
G SMAD4 SMAD family member 4 treatment IAGP
IEP 		associated with colorectal carcinoma; DNA:mutations: :
associated with colorectal carcinoma;protein:decreased expression:colorectum: 		RGD PMID:29551247 PMID:17390050 RGD:18937000, RGD:21066338 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,528...51,085,045 		JBrowse link
G SOX30 SRY-box transcription factor 30 ameliorates ISO RGD PMID:29739711 RGD:151660333 NCBI chr 5:157,625,679...157,671,480
Ensembl chr 5:157,625,679...157,671,480 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase disease_progression IEP associated with colon cancer;protein:increased activity:colon RGD PMID:7678609 RGD:150521542 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050 		JBrowse link
G VEGFA vascular endothelial growth factor A IEP associated with colorectal carcinoma;mRNA,protein:increased expression:liver: RGD PMID:22156924 RGD:15014782 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
mixed fibrolamellar hepatocellular carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKACA protein kinase cAMP-activated catalytic subunit alpha susceptibility ISO RGD PMID:28923495 RGD:151347843 NCBI chr19:14,091,688...14,117,762
Ensembl chr19:14,091,688...14,118,084 		JBrowse link
Ruijs-Aalfs syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPRTN SprT-like N-terminal domain IAGP ClinVar Annotator: match by term: Progeroid features-hepatocellular carcinoma predisposition syndrome
ClinVar Annotator: match by term: SPRTN-related condition
ClinVar Annotator: match by term: Progeroid features-hepatocellular carcinoma predisposition syndrome | ClinVar Annotator: match by term: SPRTN-related condition 		ClinVar
OMIM		 PMID:12503110 PMID:25261934 PMID:25741868 PMID:28492532 NCBI chr 1:231,338,293...231,355,023
Ensembl chr 1:231,337,104...231,355,023 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 151016
    disease of cellular proliferation 29434
      cancer 24086
        organ system cancer 23193
          gastrointestinal system cancer 3902
            hepatobiliary system cancer 1183
              biliary tract cancer + 204
              liver cancer + 1075
Path 2
Term Annotations click to browse term
  disease 151016
    disease of anatomical entity 138079
      gastrointestinal system disease 21263
        Digestive System Neoplasms 5383
          Gastrointestinal Neoplasms 5004
            gastrointestinal system cancer 3902
              hepatobiliary system cancer 1183
                biliary tract cancer + 204
                liver cancer + 1075
paths to the root