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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:colitis
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Accession:DOID:0060180 term browser browse the term
Definition:An inflammatory bowel disease that involves inflammation located_in colon. (DO)
Synonyms:exact_synonym: colitides
 primary_id: MESH:D003092
 xref: EFO:0003872;   NCI:C26723


show annotations for term's descendants           Sort by:
colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24548422 NCBI chr 6:46,601,583...46,663,690
Ensembl chr 6:40,872,856...40,920,639 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing IEP
ISO		 RGD PMID:17604368 PMID:21479819 RGD:5686754, RGD:5686898 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Adk adenosine kinase ISO RGD PMID:11123368 RGD:6482664 NCBI chr15:2,912,543...3,295,745
Ensembl chr15:2,863,244...3,246,510 		JBrowse link
G Adrb3 adrenoceptor beta 3 IEP mRNA:decreased expression:distal colon, mucosa (rat) RGD PMID:18492028 RGD:5684890 NCBI chr16:71,544,603...71,547,410
Ensembl chr16:64,841,788...64,844,552 		JBrowse link
G Ahr aryl hydrocarbon receptor ISO CTD Direct Evidence: therapeutic CTD PMID:27783946 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15821759 NCBI chr 4:151,203,948...151,251,126
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Anxa1 annexin A1 IEP protein:increased expression:colon, neutrophil RGD PMID:10489933 RGD:2306920 NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Apln apelin IEP RGD PMID:17391779 RGD:1626177 NCBI chr  X:132,058,739...132,091,518
Ensembl chr  X:127,203,823...127,213,391 		JBrowse link
G Apoa4 apolipoprotein A4 ISO human protein in mouse model RGD PMID:15254593 RGD:5685667 NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:46,539,082...46,541,469 		JBrowse link
G Aqp7 aquaporin 7 ISO associated with Infection;mRNA, protein:decreased expression:colon RGD PMID:15338270 RGD:1626292 NCBI chr 5:60,968,495...60,982,618
Ensembl chr 5:56,172,519...56,186,642 		JBrowse link
G Arg1 arginase 1 severity ISO RGD PMID:28423665 RGD:39939041 NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Arrb1 arrestin, beta 1 IEP protein:increased expression:colon (rat) RGD PMID:21066892 RGD:5509893 NCBI chr 1:163,249,654...163,321,711
Ensembl chr 1:153,838,078...153,904,061 		JBrowse link
G Atp5f1d ATP synthase F1 subunit delta treatment IEP RGD PMID:23840258 RGD:13792680 NCBI chr 7:10,211,260...10,218,989
Ensembl chr 7:9,560,608...9,565,929 		JBrowse link
G Bdnf brain-derived neurotrophic factor ISO protein:increased expression:dorsal root ganglion: RGD PMID:19932037 RGD:8657331 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bmp6 bone morphogenetic protein 6 IEP RGD PMID:22361727 RGD:7242194 NCBI chr17:26,523,704...26,785,558
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Btk Bruton tyrosine kinase ameliorates ISO Associated with candidiasis RGD PMID:25379804 RGD:124713568 NCBI chr  X:102,016,070...102,055,448
Ensembl chr  X:97,722,802...97,761,853 		JBrowse link
G Car1 carbonic anhydrase 1 IEP protein:decreased expression:urine RGD PMID:31095872 RGD:408427353 NCBI chr 2:88,550,681...88,593,454
Ensembl chr 2:86,861,897...86,872,208 		JBrowse link
G Cat catalase IDA RGD PMID:21463646 RGD:5130869 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cckbr cholecystokinin B receptor IMP RGD PMID:15102523 RGD:2311333 NCBI chr 1:169,183,578...169,193,583
Ensembl chr 1:159,771,733...159,814,881 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP RGD PMID:18690297 RGD:2307009 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 IMP RGD PMID:16399111 RGD:2307162 NCBI chr 8:132,433,711...132,439,266 JBrowse link
G Cd36 CD36 molecule ISO RGD PMID:19117124 RGD:6893503 NCBI chr 4:18,209,088...18,302,142
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd40 CD40 molecule IMP RGD PMID:15591506 RGD:5508169 NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Chek2 checkpoint kinase 2 ISO ClinVar Annotator: match by term: Colitis ClinVar PMID:10617473 PMID:11053450 PMID:11479205 PMID:11719428 PMID:11967536 More... NCBI chr12:51,448,838...51,481,159
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex treatment IEP RGD PMID:17543437 RGD:2298659 NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Ciita class II, major histocompatibility complex, transactivator severity ISO protein:increased expression:T cells:constitutive expression of transgene increases severity (mouse)
ClinVar Annotator: match by term: Colitis		 ClinVar
RGD		 PMID:25741868 PMID:28492532 PMID:17043423 RGD:5491188 NCBI chr10:5,646,854...5,694,393
Ensembl chr10:5,140,178...5,187,440 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 IEP
IMP		 mRNA, protein:decreased expression:intestine, myenteric nerve plexus RGD PMID:17586086 PMID:21330446 RGD:5131259, RGD:5490987 NCBI chr 4:85,553,163...85,596,203
Ensembl chr 4:84,224,002...84,265,904 		JBrowse link
G Ctsb cathepsin B ISO protein:increased activity:cecum, colon, spinal cord RGD PMID:21802389 RGD:5686873 NCBI chr15:41,565,607...41,586,479
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Ctsl cathepsin L ISO protein:increased activity:cecum, colon, spinal cord RGD PMID:21802389 RGD:5686873 NCBI chr17:770,104...776,266
Ensembl chr17:764,309...770,548 		JBrowse link
G Ctss cathepsin S ISO protein:increased activity:cecum, colon, spinal cord RGD PMID:21802389 RGD:5686873 NCBI chr 2:185,775,316...185,803,440
Ensembl chr 2:183,086,437...183,114,483 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 IMP RGD PMID:14738862 RGD:7257706 NCBI chr 9:83,178,645...83,185,017
Ensembl chr 9:75,729,115...75,739,425 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO mRNA:increased expression:large intestine epithelium RGD PMID:21374063 RGD:5147670 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Dusp1 dual specificity phosphatase 1 severity ISO RGD PMID:22461024 RGD:7771532 NCBI chr10:17,184,853...17,187,646 JBrowse link
G Esr2 estrogen receptor 2 IEP
ISO		 mRNA:decreased expression:colon RGD PMID:21252046 PMID:21252046 RGD:5508810, RGD:5508810 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Fgf19 fibroblast growth factor 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27580383 NCBI chr 1:209,485,813...209,490,267
Ensembl chr 1:200,056,644...200,060,287 		JBrowse link
G Flna filamin A ISO ClinVar Annotator: match by term: Colitis ClinVar PMID:25741868 PMID:28492532 PMID:30755392 NCBI chr  X:157,159,051...157,185,559
Ensembl chr  X:152,007,758...152,031,052 		JBrowse link
G Gcg glucagon ISO CTD Direct Evidence: therapeutic CTD PMID:22323126 NCBI chr 3:67,522,489...67,531,533
Ensembl chr 3:47,113,914...47,122,929 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: therapeutic CTD PMID:19617644 NCBI chr 4:148,421,315...148,431,128
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Gsta4 glutathione S-transferase alpha 4 ISO protein:increased expression:colon, epithelial cell (mouse) RGD PMID:15309552 RGD:5687963 NCBI chr 8:87,947,247...87,964,490
Ensembl chr 8:79,066,934...79,084,182 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 IEP mRNA:increased expression:kidney: RGD PMID:23307618 RGD:7245473 NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,119,088...31,151,698 		JBrowse link
G Hmox1 heme oxygenase 1 treatment IEP
ISO		 protein:increased expression:colon:
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:16365149 PMID:21444764 PMID:22261574 PMID:21853095 RGD:7207796, RGD:10766442 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hp haptoglobin treatment IEP RGD PMID:22457771 RGD:11041866 NCBI chr19:54,449,151...54,453,701
Ensembl chr19:37,539,627...37,544,523 		JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP protein:increased expression:colon: RGD PMID:22261574 RGD:7207796 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Icos inducible T-cell co-stimulator IEP protein:increased expression:T-cell RGD PMID:14731127 RGD:1624274 NCBI chr 9:69,862,042...69,900,864
Ensembl chr 9:62,383,832...62,405,672 		JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:24548422 PMID:16717119 RGD:150573704 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igf1 insulin-like growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24782617 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta treatment IEP RGD PMID:17543437 RGD:2298659 NCBI chr16:76,021,968...76,075,717
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Il10 interleukin 10 treatment IEP
ISO		 CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:19238344 PMID:21807089 PMID:22119709 PMID:24314293 PMID:21949848 More... RGD:7349385, RGD:7771532, RGD:7365024 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il17a interleukin 17A ISO
IEP		 CTD Direct Evidence: marker/mechanism
mRNA:increased expression:colon		 CTD
RGD		 PMID:24548422 PMID:14962796 PMID:20881082 RGD:4888509, RGD:4781448 NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il1b interleukin 1 beta IDA
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:23810507 PMID:24548422 PMID:22969190 RGD:7204699 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 severity ISO RGD PMID:23172891 RGD:40400694 NCBI chr 9:50,157,326...50,222,888
Ensembl chr 9:42,697,192...42,727,256 		JBrowse link
G Il33 interleukin 33 severity ISO RGD PMID:28423665 PMID:23172891 RGD:39939041, RGD:40400694 NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Il4 interleukin 4 treatment ISO CTD Direct Evidence: therapeutic CTD
RGD		 PMID:24314293 PMID:9389741 RGD:8142400 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il5 interleukin 5 ISO protein: increased expression RGD PMID:22018693 RGD:5687148 NCBI chr10:38,375,132...38,378,003
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22410118 PMID:24548422 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Itgb2 integrin subunit beta 2 ISO associated with Spirochaetales infections RGD PMID:11031123 RGD:6482227 NCBI chr20:11,061,009...11,097,242
Ensembl chr20:11,061,430...11,097,600 		JBrowse link
G Kdr kinase insert domain receptor IEP protein:increased expression:colon: RGD PMID:22261574 RGD:7207796 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Lct lactase IEP protein:decreased expression, increased expression:jejunum RGD PMID:17218984 RGD:1600240 NCBI chr13:42,334,347...42,376,872
Ensembl chr13:39,781,929...39,824,456 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 ISO RGD PMID:21983832 RGD:5508401 NCBI chr 7:124,706,246...124,867,234
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Madcam1 mucosal vascular addressin cell adhesion molecule 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16917232 NCBI chr 7:10,686,920...10,690,322
Ensembl chr 7:10,036,301...10,039,703 		JBrowse link
G Mc1r melanocortin 1 receptor ISO RGD PMID:16543288 RGD:5687320 NCBI chr19:68,360,950...68,363,877
Ensembl chr19:51,453,239...51,454,192 		JBrowse link
G Mif macrophage migration inhibitory factor IDA
ISO		 CTD Direct Evidence: therapeutic CTD
RGD		 PMID:12105854 PMID:17324399 RGD:1641979 NCBI chr20:12,767,138...12,791,222
Ensembl chr20:12,790,902...12,799,504
Ensembl chr 4:12,790,902...12,799,504 		JBrowse link
G Mir150 microRNA 150 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26937033 NCBI chr 1:104,741,487...104,741,571
Ensembl chr 1:95,605,024...95,605,108 		JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23810507 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Msh2 mutS homolog 2 IEP RGD PMID:23883737 RGD:10412318 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Muc17 mucin 17, cell surface associated treatment IEP
IDA		 mRNA:increased expression:ileum, colon RGD PMID:16964428 PMID:23395625 RGD:1625545, RGD:7349360 NCBI chr12:25,139,076...25,175,249
Ensembl chr12:19,527,321...19,538,522 		JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming treatment IEP
IDA
ISO		 mRNA:decreased expression:colon
protein:decreased sulfation:descending colon		 RGD PMID:19220658 PMID:21949848 PMID:23395625 PMID:12395902 RGD:2324675, RGD:7349385, RGD:7349360, RGD:7349356 NCBI chr 1:206,225,775...206,261,280
Ensembl chr 1:196,799,517...196,831,756 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23810507 NCBI chr 6:55,152,756...55,189,547
Ensembl chr 6:49,424,332...49,462,100 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 treatment ISO RGD PMID:30142311 RGD:42724458 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 ISO RGD PMID:20921147 RGD:5508755 NCBI chr 4:85,391,142...85,442,281
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 IEP
ISO		 mRNA:increased expression:colon RGD PMID:16891783 PMID:20921147 PMID:21471573 RGD:1600781, RGD:5508755, RGD:5508727 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Nos2 nitric oxide synthase 2 IEP
ISO		 mRNA:increased expression:colon
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:colon (mouse)		 CTD
RGD		 PMID:8698225 PMID:17449036 PMID:16866779 PMID:21930116 RGD:4891411, RGD:5509045 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nos3 nitric oxide synthase 3 IEP mRNA:increased expression:colon RGD PMID:17947450 RGD:2292124 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 IEP mRNA, protein:increased expression:neuron RGD PMID:20638179 RGD:5684542 NCBI chr 2:175,534,844...175,551,664
Ensembl chr 2:173,236,963...173,253,770 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 IEP mRNA, protein:increased expression:dorsal root ganglion RGD PMID:20638179 RGD:5684542 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Pgf placental growth factor ISO RGD PMID:20142801 RGD:6483587 NCBI chr 6:110,547,165...110,557,747
Ensembl chr 6:104,816,104...104,826,685 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma ISO RGD PMID:21244371 RGD:6482682 NCBI chr 6:54,494,247...54,529,563
Ensembl chr 6:48,766,864...48,802,043 		JBrowse link
G Pla2g2a phospholipase A2 group IIA ISO RGD PMID:17982090 RGD:6482729 NCBI chr 5:156,359,725...156,362,302
Ensembl chr 5:151,076,442...151,079,014 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha susceptibility ISO RGD PMID:20650341 RGD:5509936 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IDA RGD PMID:22126533 RGD:6484264 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Ptger4 prostaglandin E receptor 4 ISO RGD PMID:20833794 RGD:6483551 NCBI chr 2:56,061,699...56,074,594
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 treatment IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:11820457 PMID:17543437 RGD:2298659 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IEP
ISO		 protein:increased expression:nucleus
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:23810507 PMID:18623154 RGD:2298776 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Ren renin treatment ISO RGD PMID:24858618 RGD:125097500 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:44,796,091...44,807,489 		JBrowse link
G Retn resistin treatment IDA RGD PMID:22630819 RGD:7207222 NCBI chr12:6,508,653...6,511,115
Ensembl chr12:1,710,881...1,712,620 		JBrowse link
G RT1-CE13 RT1 class I, locus CE13 ISO human gene in rat model; DNA:polymorphisms:cds:HLA-B27 (human) RGD PMID:2257626 RGD:7387221 NCBI chr20:3,314,491...3,322,815 JBrowse link
G Sell selectin L IMP RGD PMID:18054560 RGD:5685703 NCBI chr13:78,950,100...78,969,604
Ensembl chr13:76,416,915...76,436,456 		JBrowse link
G Selp selectin P IEP protein:increased expression:colon RGD PMID:19147805 RGD:2312310 NCBI chr13:79,009,379...79,044,994
Ensembl chr13:76,476,295...76,511,845 		JBrowse link
G Selplg selectin P ligand ISO RGD PMID:22009715 RGD:6218987 NCBI chr12:48,457,102...48,470,444
Ensembl chr12:42,796,580...42,812,585 		JBrowse link
G Si sucrase-isomaltase IEP mRNA, protein:decreased expression:ileum RGD PMID:16964428 RGD:1625545 NCBI chr 2:159,804,568...159,884,902
Ensembl chr 2:157,506,342...157,585,260 		JBrowse link
G Sirt1 sirtuin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19940103 PMID:24548422 PMID:24782617 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Slc11a1 solute carrier family 11 member 1 ISO RGD PMID:19016783 RGD:5684975 NCBI chr 9:83,406,327...83,417,252
Ensembl chr 9:75,957,316...75,968,101 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 ISO RGD PMID:16717119 RGD:150573704 NCBI chr10:5,389,574...5,391,265
Ensembl chr10:4,882,560...4,884,383 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17551092 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Syk spleen associated tyrosine kinase ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Colitis		 CTD
ClinVar		 PMID:25741868 PMID:28492532 PMID:33782605 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Tac1 tachykinin, precursor 1 IEP RGD PMID:18715640 RGD:2304260 NCBI chr 4:36,645,344...36,653,548
Ensembl chr 4:35,679,704...35,687,178 		JBrowse link
G Tacr1 tachykinin receptor 1 IEP RGD PMID:18715640 RGD:2304260 NCBI chr 4:116,478,617...116,647,492
Ensembl chr 4:114,920,844...115,089,733 		JBrowse link
G Tacr2 tachykinin receptor 2 IEP
IMP		 RGD PMID:18715640 PMID:12490601 RGD:2304260, RGD:5147478 NCBI chr20:30,751,645...30,766,181
Ensembl chr20:30,208,907...30,223,446 		JBrowse link
G Tes testin LIM domain protein ISO CTD Direct Evidence: therapeutic CTD PMID:39237074 NCBI chr 4:46,331,257...46,369,782
Ensembl chr 4:45,365,285...45,403,829 		JBrowse link
G Tff1 trefoil factor 1 IEP RGD PMID:8836141 RGD:625375 NCBI chr20:9,237,095...9,240,956
Ensembl chr20:9,235,736...9,239,597 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24548422 NCBI chr 7:19,408,539...19,459,558
Ensembl chr 7:17,521,919...17,571,839 		JBrowse link
G Tlr3 toll-like receptor 3 IEP mRNA:increased expression:large intestine mucosa (rat) RGD PMID:20011045 RGD:5128708 NCBI chr16:53,554,916...53,572,321
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr4 toll-like receptor 4 IEP
ISO		 protein:increased expression:colon RGD PMID:19002562 PMID:19924809 RGD:2312573, RGD:7794773 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23810507 PMID:24548422 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 severity ISO RGD PMID:24453980 RGD:126925972 NCBI chr 9:20,259,227...20,276,879
Ensembl chr 9:12,763,819...12,779,203 		JBrowse link
G Tst thiosulfate sulfurtransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19647029 NCBI chr 7:111,828,557...111,836,980
Ensembl chr 7:109,948,062...109,957,216 		JBrowse link
G Ucn urocortin IEP mRNA:altered expression:distal colon (rat) RGD PMID:21330446 RGD:5490987 NCBI chr 6:30,958,086...30,958,916
Ensembl chr 6:25,238,120...25,238,950 		JBrowse link
G Ucn2 urocortin 2 IEP mRNA:increased expression:colon (rat) RGD PMID:17586086 RGD:5131259 NCBI chr 8:118,516,111...118,517,660
Ensembl chr 8:109,638,285...109,639,172 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 IEP protein:increased expression:colon: RGD PMID:22261574 RGD:7207796 NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
G Vip vasoactive intestinal peptide ISO associated with Gram-Negative Bacterial Infections RGD PMID:19661153 RGD:5685605 NCBI chr 1:44,470,232...44,478,561
Ensembl chr 1:42,065,120...42,073,216 		JBrowse link
G Vipr2 vasoactive intestinal peptide receptor 2 ISO RGD PMID:21295288 RGD:5685384 NCBI chr 6:143,139,672...143,213,609
Ensembl chr 6:137,001,511...137,070,597 		JBrowse link
chemical colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO protein:increased expression:small intestine, large intestine:extracellular space (mouse) RGD PMID:26401072 RGD:11555935 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Ace2 angiotensin converting enzyme 2 severity ISO Ace2 knockout
Ace2 inhibitor		 RGD PMID:22837003 PMID:19517214 RGD:40818307, RGD:40818410 NCBI chr  X:33,925,458...33,972,851
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Casp3 caspase 3 treatment ISO RGD PMID:28740344 RGD:13782278 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 treatment ISO RGD PMID:28740344 RGD:13782278 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Serpina1 serpin family A member 1 treatment ISO RGD PMID:23835442 RGD:14695050 NCBI chr 6:128,631,101...128,653,125
Ensembl chr 6:122,866,312...122,888,339 		JBrowse link
Clostridium difficile colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il23a interleukin 23 subunit alpha severity ISO RGD PMID:26455347 RGD:11097134 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:721,809...723,923 		JBrowse link
G Il33 interleukin 33 treatment
severity		 ISO RGD PMID:32156806 PMID:32156806 RGD:40400894, RGD:40400894 NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
Experimental Colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme treatment ISO RGD PMID:24239644 PMID:17342403 RGD:40400720, RGD:40400748 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Acer3 alkaline ceramidase 3 severity ISO mRNA,protein:decreased expression, decreased activity:colon: RGD PMID:26938296 PMID:26938296 RGD:35673322, RGD:35673322 NCBI chr 1:161,915,397...162,017,802
Ensembl chr 1:152,504,186...152,606,591 		JBrowse link
G Adam17 ADAM metallopeptidase domain 17 treatment IEP RGD PMID:11884025 RGD:632022 NCBI chr 6:46,601,583...46,663,690
Ensembl chr 6:40,872,856...40,920,639 		JBrowse link
G Adrb3 adrenoceptor beta 3 no_association IEP mRNA:unaltered expression:colon (rat) RGD PMID:11803250 RGD:5684894 NCBI chr16:71,544,603...71,547,410
Ensembl chr16:64,841,788...64,844,552 		JBrowse link
G Ager advanced glycosylation end product-specific receptor treatment IEP RGD PMID:29572553 RGD:152995414 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 treatment IEP RGD PMID:29572553 RGD:152995414 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Atm ATM serine/threonine kinase exacerbates ISO RGD PMID:20179206 RGD:126781749 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha treatment IEP RGD PMID:25689466 RGD:13703055 NCBI chr18:73,567,537...73,575,473
Ensembl chr18:71,292,374...71,300,794 		JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP RGD PMID:29572553 RGD:152995414 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 exacerbates ISO RGD PMID:26037070 RGD:11537970 NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Cd68 Cd68 molecule treatment ISO RGD PMID:25004394 RGD:40925931 NCBI chr10:54,880,562...54,882,441
Ensembl chr10:54,381,815...54,383,697 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit treatment IMP RGD PMID:29572553 RGD:152995414 NCBI chr 1:126,123,425...126,249,181
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Csf1r colony stimulating factor 1 receptor ameliorates ISO RGD PMID:23451116 RGD:150524300 NCBI chr18:56,834,152...56,860,804
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Csf3 colony stimulating factor 3 treatment ISO RGD PMID:16689657 RGD:11039462 NCBI chr10:84,157,485...84,159,860
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Ereg epiregulin ISO protein:increased expression:colonic mucosa (mouse) RGD PMID:20498653 RGD:39457688 NCBI chr14:17,311,485...17,325,260
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit treatment ISO RGD PMID:31160593 RGD:126779602 NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G Fas Fas cell surface death receptor treatment IDA RGD PMID:22368862 RGD:10054108 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fgf10 fibroblast growth factor 10 treatment ISO
IDA		 human protein in mouse model
human gene product in mouse model
human protein in mouse model with bacterial delivery system		 RGD PMID:10381813 PMID:11952999 PMID:23676805 PMID:19736360 RGD:126928132, RGD:127284874, RGD:127284855, RGD:126928133 NCBI chr 2:52,533,939...52,610,980
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Fgf7 fibroblast growth factor 7 treatment ISO human protein in mouse model RGD PMID:10219846 RGD:126928136 NCBI chr 3:133,734,557...133,786,678
Ensembl chr 3:113,281,283...113,332,929 		JBrowse link
G Foxp3 forkhead box P3 treatment ISO
IDA		 mRNA:increased expression:mucosa:
protein:increased expression:colon:		 RGD PMID:26925602 PMID:28733028 PMID:27498708 PMID:17229795 RGD:38455994, RGD:38549362, RGD:14975101, RGD:38455995 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Hamp hepcidin antimicrobial peptide IEP protein:increased expression:colon RGD PMID:24764672 RGD:11041628 NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Hmgb1 high mobility group box 1 treatment IEP RGD PMID:29572553 RGD:152995414 NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hsf1 heat shock transcription factor 1 IEP protein:increased acetylation:colon (rat) RGD PMID:25608526 RGD:10402402 NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment IMP
IEP		 RGD PMID:10092309 PMID:29572553 RGD:11522714, RGD:152995414 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ifng interferon gamma IEP
ISO		 protein:increased expression:plasma: RGD PMID:15030379 PMID:27498708 RGD:10755756, RGD:14975101 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Ifngr1 interferon gamma receptor 1 ameliorates ISO RGD PMID:25918247 RGD:124715468 NCBI chr 1:16,152,811...16,171,439
Ensembl chr 1:14,333,187...14,351,785 		JBrowse link
G Il10 interleukin 10 treatment ISO
IEP		 associated with Helicobacter Infections RGD PMID:16982822 PMID:29572553 PMID:27815529 PMID:25727887 RGD:11049170, RGD:152995414, RGD:14975260, RGD:11049485 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il1b interleukin 1 beta treatment ISO RGD PMID:31175857 RGD:14975282 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO human protein in a rat model RGD PMID:8978354 RGD:8551835 NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il2 interleukin 2 IEP RGD PMID:16630696 RGD:8662978 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il23a interleukin 23 subunit alpha severity ISO mRNA:increased expression:colon (mouse) RGD PMID:24028683 RGD:39458035 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:721,809...723,923 		JBrowse link
G Il25 interleukin 25 treatment ISO RGD PMID:19118508 RGD:39456129 NCBI chr15:32,378,750...32,382,141
Ensembl chr15:28,408,842...28,411,893 		JBrowse link
G Il33 interleukin 33 severity
treatment		 ISO RGD PMID:25112700 PMID:28423665 RGD:39938951, RGD:39939041 NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Il6 interleukin 6 treatment IEP
ISO
IDA		 RGD PMID:16630696 PMID:27096537 PMID:16133010 RGD:8662978, RGD:11062146, RGD:11062139 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Irf9 interferon regulatory factor 9 ameliorates ISO RGD PMID:25918247 RGD:124715468 NCBI chr15:33,065,422...33,071,881
Ensembl chr15:29,095,789...29,101,236 		JBrowse link
G Itga2 integrin subunit alpha 2 treatment ISO RGD PMID:16534417 RGD:11530069 NCBI chr 2:48,253,412...48,354,509
Ensembl chr 2:46,523,948...46,621,481 		JBrowse link
G Itga4 integrin subunit alpha 4 IEP protein:increased expression:colon (rat) RGD PMID:12183646 RGD:729408 NCBI chr 3:84,569,487...84,646,276
Ensembl chr 3:64,163,085...64,233,715 		JBrowse link
G Jak2 Janus kinase 2 treatment IEP RGD PMID:29572553 RGD:152995414 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 IEP mRNA, protein:increased expression:colon RGD PMID:23986198 RGD:10412026 NCBI chr15:351,065...1,057,117
Ensembl chr15:302,214...1,001,198 		JBrowse link
G Kdr kinase insert domain receptor ISO protein:increased expression:colon RGD PMID:19013462 RGD:5684406 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Kl Klotho ISO mRNA:decreased expression:kidney: RGD PMID:20004202 RGD:10403055 NCBI chr12:5,326,003...5,367,016
Ensembl chr12:490,399...530,080 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 treatment IEP RGD PMID:27028006 RGD:13800882 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 treatment IDA RGD PMID:29037916 RGD:13800567 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mif macrophage migration inhibitory factor severity ISO RGD PMID:15807847 RGD:36947390 NCBI chr20:12,767,138...12,791,222
Ensembl chr20:12,790,902...12,799,504
Ensembl chr 4:12,790,902...12,799,504 		JBrowse link
G Mir146a microRNA 146a ISO miRNA:increased expression:colon, small intestine (mouse) RGD PMID:24092752 RGD:126925183 NCBI chr10:28,349,996...28,350,090
Ensembl chr10:27,848,516...27,848,610 		JBrowse link
G Mir155 microRNA 155 treatment ISO
IMP		 associated with Helicobacter Infections RGD PMID:30927737 PMID:28461115 PMID:28752563 PMID:30253332 PMID:21880981 More... RGD:21079443, RGD:25314295, RGD:24922208, RGD:21081536, RGD:21079473, RGD:21079463 NCBI chr11:37,261,114...37,261,178
Ensembl chr11:23,774,654...23,774,718 		JBrowse link
G Mir21 microRNA 21 ameliorates ISO RGD PMID:23826144 RGD:41404691 NCBI chr10:71,902,600...71,902,691
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mmp2 matrix metallopeptidase 2 treatment IEP RGD PMID:23323009 RGD:13207328 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment IEP RGD PMID:23323009 RGD:13207328 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mpo myeloperoxidase treatment IEP RGD PMID:29572553 RGD:152995414 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Msc musculin exacerbates
no_association		 ISO RGD PMID:33448336 PMID:36848960 RGD:596936211, RGD:596936221 NCBI chr 5:9,330,522...9,336,391
Ensembl chr 5:4,547,405...4,553,203 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor exacerbates ISO RGD PMID:25362351 RGD:150521530 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 treatment IEP RGD PMID:22350949 RGD:10412739 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkbia NFKB inhibitor alpha treatment IDA RGD PMID:21642017 RGD:10413866 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 IEP protein:increased expression:colonic mucosa: RGD PMID:22997830 RGD:13204727 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Npy neuropeptide Y treatment IMP RGD PMID:20533056 RGD:10448943 NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha treatment IEP RGD PMID:24115822 RGD:11080973 NCBI chr14:33,360,027...33,408,604
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta treatment IEP RGD PMID:24115822 RGD:11080973 NCBI chr18:56,770,348...56,809,228
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Phex phosphate regulating endopeptidase X-linked ISO mRNA:decreased expression:bone: RGD PMID:16890604 RGD:11556253 NCBI chr  X:41,422,561...41,671,226
Ensembl chr  X:37,610,760...37,854,469 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma susceptibility ISO RGD PMID:20347874 RGD:38599183 NCBI chr 6:54,494,247...54,529,563
Ensembl chr 6:48,766,864...48,802,043 		JBrowse link
G Ptger4 prostaglandin E receptor 4 treatment IMP RGD PMID:12100473 RGD:727388 NCBI chr 2:56,061,699...56,074,594
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit treatment IEP RGD PMID:29572553 RGD:152995414 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rnasel ribonuclease L severity ISO RGD PMID:23567782 RGD:40902808 NCBI chr13:68,446,641...68,460,804
Ensembl chr13:65,901,459...65,908,704 		JBrowse link
G Slc11a1 solute carrier family 11 member 1 ISO RGD PMID:19116231 RGD:5684934 NCBI chr 9:83,406,327...83,417,252
Ensembl chr 9:75,957,316...75,968,101 		JBrowse link
G Smad3 SMAD family member 3 ISO protein:increased expression:colon RGD PMID:30064196 RGD:597830080 NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smad4 SMAD family member 4 susceptibility ISO RGD PMID:23090737 RGD:12880038 NCBI chr18:69,518,988...69,549,684
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 treatment IEP RGD PMID:29572553 RGD:152995414 NCBI chr10:103,692,579...103,695,975
Ensembl chr10:103,193,537...103,197,787 		JBrowse link
G Tnf tumor necrosis factor treatment IMP
IEP		 RGD PMID:21296062 PMID:29572553 RGD:8661763, RGD:152995414 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A treatment IMP RGD PMID:21296062 RGD:8661763 NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO protein:increased expression:colon RGD PMID:19013462 RGD:5684406 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
ischemic colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Serpine1 serpin family E member 1 susceptibility ISO DNA:polymorphism:promoter:rs1799768 (human) RGD PMID:25656775 RGD:13208543 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO RGD PMID:15770733 RGD:1580570 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
Proctocolitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1rn interleukin 1 receptor antagonist ISO protein:increased concentration:serum (human) RGD PMID:9802632 RGD:6909134 NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
ulcerative colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A susceptibility ISO RGD PMID:15505619 RGD:1598568 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 ISO mRNA:decreased expression:colonic mucosa RGD PMID:21987487 RGD:7241281 NCBI chr 1:183,564,652...183,591,328
Ensembl chr 1:174,133,288...174,160,184 		JBrowse link
G Adcy7 adenylate cyclase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067910 NCBI chr19:34,913,154...34,972,366
Ensembl chr19:18,740,875...18,776,311 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:increased expression:serum RGD PMID:16432373 RGD:5686726 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Adrb2 adrenoceptor beta 2 IEP protein:decreased expression:large intestine mucosa,spleen RGD PMID:22772914 RGD:7175063 NCBI chr18:57,912,760...57,914,802
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:35999755 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type ISO protein:increased expression:large intestine epithelium RGD PMID:7679252 RGD:5509621 NCBI chr10:55,456,923...55,469,239
Ensembl chr10:54,958,271...54,970,542 		JBrowse link
G Alpi alkaline phosphatase, intestinal ISO protein:decreased expression:colonic mucosa RGD PMID:22783049 RGD:14367879 NCBI chr 9:95,221,314...95,224,780
Ensembl chr 9:87,773,411...87,776,877 		JBrowse link
G Apln apelin ISO protein:increased expression:intestine RGD PMID:17391779 RGD:1626177 NCBI chr  X:132,058,739...132,091,518
Ensembl chr  X:127,203,823...127,213,391 		JBrowse link
G Apoa4 apolipoprotein A4 severity ISO DNA:missense mutation:cds:p.Q360H (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:35999755 PMID:17206692 RGD:5685660 NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:46,539,082...46,541,469 		JBrowse link
G Aqp7 aquaporin 7 severity ISO mRNA, protein:decreased expression:colon RGD PMID:15338270 RGD:1626292 NCBI chr 5:60,968,495...60,982,618
Ensembl chr 5:56,172,519...56,186,642 		JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18836448 NCBI chr 9:83,269,884...83,300,610
Ensembl chr 9:75,820,770...75,851,471 		JBrowse link
G Bcl6 BCL6, transcription repressor ISO CTD Direct Evidence: therapeutic CTD PMID:38164749 NCBI chr11:90,358,753...90,382,049
Ensembl chr11:76,854,090...76,877,389 		JBrowse link
G Brinp3 BMP/retinoic acid inducible neural specific 3 ISO mRNA,protein:decreased expression:intestine RGD PMID:25171508 RGD:14398484 NCBI chr13:60,964,127...61,397,044
Ensembl chr13:58,413,883...58,846,770 		JBrowse link
G Btnl2 butyrophilin-like 2 susceptibility ISO DNA:SNPs: : rs2294881,rs9268480,rs2076523(human) RGD PMID:19659809 RGD:9685032 NCBI chr20:4,492,100...4,505,932
Ensembl chr20:4,489,517...4,503,341 		JBrowse link
G C3 complement C3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35999755 NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Card9 caspase recruitment domain family, member 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr 3:29,569,907...29,578,402
Ensembl chr 3:9,171,815...9,180,237 		JBrowse link
G Casp3 caspase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24055189 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 treatment IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16306769 PMID:21887805 RGD:7488892 NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 ISO protein:increased expression:colon RGD PMID:10433925 RGD:6483784 NCBI chr10:67,514,095...67,515,945
Ensembl chr10:67,016,446...67,018,303 		JBrowse link
G Ccny cyclin Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 NCBI chr17:62,079,925...62,207,780
Ensembl chr17:57,384,176...57,522,378 		JBrowse link
G Ccr3 C-C motif chemokine receptor 3 ISO RGD PMID:21077277 RGD:6892920 NCBI chr 8:132,463,533...132,511,601
Ensembl chr 8:123,616,236...123,634,990 		JBrowse link
G Ccr6 C-C motif chemokine receptor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16306769 NCBI chr 1:55,022,037...55,055,857
Ensembl chr 1:52,474,168...52,498,603 		JBrowse link
G Cd40 CD40 molecule ISO protein:increased expression:intestine, epithelial cell RGD PMID:20133813 RGD:5490590 NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Cdh1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chr19:51,402,178...51,471,572
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdh3 cadherin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chr19:51,303,414...51,353,900
Ensembl chr19:34,393,727...34,444,084 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A disease_progression ISO RGD PMID:15743319 RGD:8662406 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cfb complement factor B ISO CTD Direct Evidence: marker/mechanism CTD PMID:35999755 NCBI chr20:3,975,271...3,981,138
Ensembl chr20:3,951,474...3,976,505 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit ISO mRNA:increased expression:intestine: RGD PMID:27051591 RGD:151667910 NCBI chr 1:126,123,425...126,249,181
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain IEP Protein:increased expression:large intestine mucosa RGD PMID:17011522 RGD:1600887 NCBI chr20:11,473,645...11,582,111
Ensembl chr20:11,474,104...11,582,593 		JBrowse link
G Col1a1 collagen type I alpha 1 chain ISO RGD PMID:17939044 RGD:5688304 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col6a3 collagen type VI alpha 3 chain ISO protein:increased expression:serum (human) RGD PMID:32245981 RGD:401900121 NCBI chr 9:98,809,171...98,887,060
Ensembl chr 9:91,361,583...91,439,471 		JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 9:83,216,040...83,220,225
Ensembl chr 9:75,766,770...75,771,084 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 9:83,178,645...83,185,017
Ensembl chr 9:75,729,115...75,739,425 		JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 ISO mRNA:increased expression:peripheral blood immature plasma cells (human) RGD PMID:21087446 RGD:6480657 NCBI chr  X:70,884,293...70,886,944
Ensembl chr  X:66,844,318...66,846,969 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ISO mRNA:increased expression:peripheral blood immature plasma cells (human) RGD PMID:21087446 RGD:6480657 NCBI chr13:42,630,383...42,634,288
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 susceptibility ISO DNA:SNPs:multiple (human) RGD PMID:28811712 RGD:151665177 NCBI chr 3:179,694,647...179,709,083
Ensembl chr 3:159,275,947...159,290,383 		JBrowse link
G Dap death-associated protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 2:83,910,113...83,962,673
Ensembl chr 2:82,199,280...82,251,752 		JBrowse link
G Defa5 defensin alpha 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20452301 NCBI chr16:77,044,994...77,047,318
Ensembl chr16:70,342,530...70,344,836 		JBrowse link
G Dpep1 dipeptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35999755 NCBI chr19:68,118,270...68,143,781
Ensembl chr19:51,219,660...51,235,257 		JBrowse link
G Duox2 dual oxidase 2 ISO mRNA:increased expression:colon (human) RGD PMID:19759286 RGD:40924645 NCBI chr 3:129,680,543...129,698,886
Ensembl chr 3:109,226,924...109,245,902 		JBrowse link
G Ecm1 extracellular matrix protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406 NCBI chr 2:185,976,439...185,981,656
Ensembl chr 2:183,287,322...183,292,671 		JBrowse link
G Ephb2 Eph receptor B2 ameliorates IDA RGD PMID:33722292 RGD:127285641 NCBI chr 5:154,179,065...154,360,459
Ensembl chr 5:148,897,246...149,077,059 		JBrowse link
G Esr2 estrogen receptor 2 ISO mRNA:decreased expression:colon RGD PMID:21252046 RGD:5508810 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G F2 coagulation factor II, thrombin ISO RGD PMID:21593018 RGD:5147754 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G Fas Fas cell surface death receptor treatment IEP RGD PMID:30122878 RGD:13792562 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand treatment IEP RGD PMID:30122878 RGD:13792562 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fcgr2a Fc gamma receptor 2A susceptibility ISO DNA:polymorphism: :p.A519G (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs1801274 (human)		 CTD
RGD		 PMID:19915573 PMID:20228799 PMID:20848524 PMID:19915573 RGD:5147918, RGD:5147922 NCBI chr13:85,813,516...85,830,269
Ensembl chr13:83,280,784...83,295,967 		JBrowse link
G Fgf7 fibroblast growth factor 7 ISO mRNA:increased expression:colon, lamina propria, myofibroblasts (human) RGD PMID:9358773 RGD:126928145 NCBI chr 3:133,734,557...133,786,678
Ensembl chr 3:113,281,283...113,332,929 		JBrowse link
G Gc GC, vitamin D binding protein susceptibility ISO DNA:polymorphism:cds:p.T420K(human) RGD PMID:21832969 RGD:5509866 NCBI chr14:18,916,255...18,951,670
Ensembl chr14:18,632,135...18,667,567 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:19617644 NCBI chr 4:148,421,315...148,431,128
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Gna12 G protein subunit alpha 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr12:18,919,629...19,000,185
Ensembl chr12:13,805,698...13,886,255 		JBrowse link
G Gpr65 G-protein coupled receptor 65 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30616622 NCBI chr 6:123,245,534...123,262,758
Ensembl chr 6:117,515,648...117,536,512 		JBrowse link
G Gpx1 glutathione peroxidase 1 ISO protein:decreased expression:erythrocyte RGD PMID:20186929 RGD:11352754 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gpx2 glutathione peroxidase 2 disease_progression ISO protein:increased expression:large intestine (human) RGD PMID:18479189 RGD:152998902 NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:95,493,589...95,496,877 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 susceptibility ISO DNA:deletion: : RGD PMID:17565649 PMID:28626742 PMID:26604430 RGD:5490554, RGD:14700999, RGD:11538341 NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 susceptibility ISO DNA:deletion: : RGD PMID:17565649 PMID:26604430 RGD:5490554, RGD:11538341 NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G Herc2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 NCBI chr 1:116,009,681...116,243,888
Ensembl chr 1:106,880,084...107,108,134 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chr 3:172,606,220...172,667,758
Ensembl chr 3:152,186,787...152,248,320 		JBrowse link
G Hnmt histamine N-methyltransferase ISO RGD PMID:18340362 RGD:5509777 NCBI chr 3:26,978,274...27,010,291
Ensembl chr 3:6,591,463...6,624,012 		JBrowse link
G Hp haptoglobin ISO CTD Direct Evidence: marker/mechanism CTD PMID:35999755 NCBI chr19:54,449,151...54,453,701
Ensembl chr19:37,539,627...37,544,523 		JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 ISO protein:increased expression:colon mucosa, epithelium (human) RGD PMID:22297444 RGD:5688753 NCBI chr10:37,908,866...37,951,994
Ensembl chr10:37,408,025...37,449,001 		JBrowse link
G Htra1 HtrA serine peptidase 1 ISO protein:decreased expression:colonic epithelium,colonic mucosa (human) RGD PMID:28586045 RGD:152985530 NCBI chr 1:194,928,069...194,977,619
Ensembl chr 1:185,497,735...185,547,379 		JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP
ISO		 mRNA:increased expression:substantia nigra (rat)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:15553846 PMID:20584104 RGD:4145388 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Icoslg inducible T-cell co-stimulator ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr20:10,600,078...10,610,385
Ensembl chr20:10,600,420...10,610,703 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor ISO protein:altered expression:colon RGD PMID:18938767 RGD:5686432 NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Igf2 insulin-like growth factor 2 disease_progression ISO RGD PMID:16088202 RGD:5509966 NCBI chr 1:207,243,873...207,261,263
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Ikzf1 IKAROS family zinc finger 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr14:90,468,696...90,556,522
Ensembl chr14:86,255,065...86,342,416 		JBrowse link
G Il10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:18836448 PMID:20228799 PMID:26660358 PMID:28120341 RGD:14975255, RGD:14975153 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il12b interleukin 12B ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406 PMID:20228799 PMID:21297633 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il18rap interleukin 18 receptor accessory protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr 9:50,263,723...50,296,583
Ensembl chr 9:42,768,220...42,800,959 		JBrowse link
G Il1b interleukin 1 beta IEP
ISO		 protein:increased expression:lung
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:12133438 PMID:15955209 PMID:20452301 PMID:22119283 PMID:24812904 RGD:10450593 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1r2 interleukin 1 receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 9:49,879,928...49,920,374
Ensembl chr 9:42,384,433...42,424,725 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO DNA:repeats:intron:IVS2+914_1000dup IL1RN*2 (human) RGD PMID:8119534 RGD:6909136 NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il23r interleukin 23 receptor ISO DNA:SNP,Haplotype: :rs1884444(human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:18438406 PMID:19122664 PMID:20228799 PMID:23093364 RGD:8549574 NCBI chr 4:97,910,230...98,003,759
Ensembl chr 4:96,580,714...96,674,021 		JBrowse link
G Il33 interleukin 33 severity
treatment		 ISO mRNA:increased expression:sigmoid colon RGD PMID:25112700 PMID:21037074 PMID:28802904 RGD:39938951, RGD:40813742, RGD:39938966 NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Il7r interleukin 7 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 2:60,179,561...60,204,937
Ensembl chr 2:58,454,217...58,477,757 		JBrowse link
G Irf4 interferon regulatory factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:38164749 NCBI chr17:33,930,460...33,948,842
Ensembl chr17:33,721,811...33,740,070 		JBrowse link
G Irf5 interferon regulatory factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 4:59,092,914...59,104,596
Ensembl chr 4:58,127,640...58,139,267 		JBrowse link
G Irgm immunity-related GTPase M ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr10:33,734,640...33,742,720
Ensembl chr10:33,233,455...33,241,578 		JBrowse link
G Jak2 Janus kinase 2 ISO DNA:SNP: :rs10758669 (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:20228799 PMID:21297633 PMID:22269120 RGD:6483020 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Kdr kinase insert domain receptor ISO protein:increased expression:colon RGD PMID:19013462 RGD:5684406 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Kif21b kinesin family member 21B ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr13:50,127,842...50,177,822
Ensembl chr13:47,576,160...47,626,127 		JBrowse link
G Lamb1 laminin subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chr 6:53,562,849...53,630,118
Ensembl chr 6:47,835,525...47,902,585 		JBrowse link
G Lsp1 lymphocyte-specific protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 1:207,044,157...207,077,891
Ensembl chr 1:197,614,687...197,648,416 		JBrowse link
G Ltf lactotransferrin ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:16640825 PMID:35999755 NCBI chr 8:119,878,344...119,901,189
Ensembl chr 8:110,999,948...111,022,795 		JBrowse link
G Masp2 MBL associated serine protease 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12904520 NCBI chr 5:164,319,017...164,332,686
Ensembl chr 5:159,035,911...159,049,580 		JBrowse link
G Mir155 microRNA 155 ISO miRNA:decreased expression:feces
miRNA:increased expression:colon		 RGD PMID:30927737 PMID:29668922 PMID:29325325 PMID:29438285 RGD:21079443, RGD:24922213, RGD:24922207, RGD:21403682 NCBI chr11:37,261,114...37,261,178
Ensembl chr11:23,774,654...23,774,718 		JBrowse link
G Mir31 microRNA 31 ISO miRNA:increased expression:colon RGD PMID:29438285 RGD:21403682 NCBI chr 5:108,714,849...108,714,954 JBrowse link
G Mmp1 matrix metallopeptidase 1 IDA RGD PMID:18837084 RGD:7207395 NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22119283 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20380826 PMID:22119283 PMID:24055189 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mst1 macrophage stimulating 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406 PMID:20228799 NCBI chr 8:117,646,485...117,652,016
Ensembl chr 8:108,768,839...108,773,416 		JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase susceptibility ISO DNA:polymorphism: :66A>G (human) RGD PMID:21947961 RGD:5508217 NCBI chr 1:36,695,376...36,727,341
Ensembl chr 1:34,867,089...34,899,425 		JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming IEP mRNA:altered expression: : RGD PMID:12870797 RGD:2324685 NCBI chr 1:206,225,775...206,261,280
Ensembl chr 1:196,799,517...196,831,756 		JBrowse link
G Nkx2-3 NK2 homeobox 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 PMID:18438406 PMID:20228799 NCBI chr 1:252,427,356...252,430,309
Ensembl chr 1:242,478,130...242,481,083 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20452301 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr10:84,086,317...84,092,673
Ensembl chr10:83,590,071...83,598,620 		JBrowse link
G Pon1 paraoxonase 1 ISO mRNA:decreased expression:colon (human) RGD PMID:17664137 RGD:5509924 NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:33,294,722...33,321,360 		JBrowse link
G Pon3 paraoxonase 3 ISO mRNA:decreased expression:colon (human) RGD PMID:17664137 RGD:5509924 NCBI chr 4:34,323,546...34,350,244
Ensembl chr 4:33,349,168...33,383,855 		JBrowse link
G Prdm1 PR/SET domain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr20:49,542,465...49,564,088
Ensembl chr20:47,959,858...47,981,488 		JBrowse link
G Psmg1 proteasome assembly chaperone 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr11:48,745,581...48,755,040
Ensembl chr11:35,276,011...35,285,622 		JBrowse link
G Ptger4 prostaglandin E receptor 4 ISO RGD PMID:21818367 RGD:6483532 NCBI chr 2:56,061,699...56,074,594
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 IMP RGD PMID:17429720 RGD:2300267 NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP RGD PMID:17429720 RGD:2300267 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 NCBI chr18:63,498,890...63,564,571
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:15955209 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20452301 NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G RT1-Bb RT1 class II, locus Bb ISO RGD PMID:31038770 RGD:14865009 NCBI chr20:4,598,475...4,604,118
Ensembl chr20:4,596,559...4,607,597 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25559196 NCBI chr20:4,550,594...4,560,182
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
G Sell selectin L ISO DNA:polymorphism: :p.F206L (human) RGD PMID:19212205 RGD:13464267 NCBI chr13:78,950,100...78,969,604
Ensembl chr13:76,416,915...76,436,456 		JBrowse link
G Selp selectin P ISO protein:increased expression:serum RGD PMID:21526498 RGD:6218993 NCBI chr13:79,009,379...79,044,994
Ensembl chr13:76,476,295...76,511,845 		JBrowse link
G Slc11a1 solute carrier family 11 member 1 ISO DNA:transition, repeat:promoter:-237C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter (human)		 CTD
RGD		 PMID:16059695 PMID:18340647 PMID:11929588 RGD:5684939, RGD:5684968 NCBI chr 9:83,406,327...83,417,252
Ensembl chr 9:75,957,316...75,968,101 		JBrowse link
G Slc26a3 solute carrier family 26 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915573 NCBI chr 6:53,751,415...53,792,300
Ensembl chr 6:48,023,892...48,064,772 		JBrowse link
G Sphk1 sphingosine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24055189 NCBI chr10:102,257,413...102,263,086
Ensembl chr10:101,758,711...101,764,240 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO DNA:SNP: :rs744166 (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:18438405 PMID:20228799 PMID:22269120 RGD:6483020 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Thbd thrombomodulin ISO protein:decreased expression:colon, blood vessel RGD PMID:17557119 RGD:5685011 NCBI chr 3:156,316,526...156,320,178
Ensembl chr 3:135,862,835...135,867,193 		JBrowse link
G Tnf tumor necrosis factor treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism
protein:increased expression:lung		 CTD
RGD		 PMID:19617644 PMID:20452301 PMID:22119283 PMID:25204186 PMID:28120341 More... RGD:10450577, RGD:14975153, RGD:10450593 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 severity ISO mRNA,protein:increased expression, decreased expression:colonic mucosa (human) RGD PMID:28842689 RGD:151347619 NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Tnfsf15 TNF superfamily member 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr 5:82,150,376...82,171,743
Ensembl chr 5:77,139,878...77,156,228 		JBrowse link
G Tp53 tumor protein p53 ISO GAD PMID:15118671 RGD:1331525 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15553846 NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO protein:increased expression:plasma, large intestine mucosa RGD PMID:19013462 RGD:5684406 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vip vasoactive intestinal peptide severity ISO mRNA:decreased expression:colon RGD PMID:22143367 RGD:5685619 NCBI chr 1:44,470,232...44,478,561
Ensembl chr 1:42,065,120...42,073,216 		JBrowse link
G Vipr1 vasoactive intestinal peptide receptor 1 ISO RGD PMID:17611633 RGD:5685618 NCBI chr 8:130,181,219...130,217,098
Ensembl chr 8:121,310,248...121,339,585 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19139
    disease of anatomical entity 18451
      gastrointestinal system disease 7197
        intestinal disease 3106
          inflammatory bowel disease 488
            colitis 259
              Clostridium difficile colitis 2
              Cutaneous Photosensitivity and Colitis, Lethal 0
              Experimental Colitis 70
              Leukoencephalopathy, Arthritis, Colitis, and Hypogammaglobulinemia 0
              Proctocolitis 1
              chemical colitis 5
              diversion colitis 0
              indeterminate colitis 0
              infectious colitis 0
              ischemic colitis 2
              microscopic colitis + 0
              pancolitis 0
              ulcerative colitis + 125
Path 2
Term Annotations click to browse term
  disease 19139
    Pathological Conditions, Signs and Symptoms 13625
      Pathologic Processes 8329
        Inflammation 2842
          gastroenteritis 571
            inflammatory bowel disease 488
              colitis 259
                Clostridium difficile colitis 2
                Cutaneous Photosensitivity and Colitis, Lethal 0
                Experimental Colitis 70
                Leukoencephalopathy, Arthritis, Colitis, and Hypogammaglobulinemia 0
                Proctocolitis 1
                chemical colitis 5
                diversion colitis 0
                indeterminate colitis 0
                infectious colitis 0
                ischemic colitis 2
                microscopic colitis + 0
                pancolitis 0
                ulcerative colitis + 125
paths to the root